Digital Commons Network^™

Louis Dover V. Kyle Laskoskie

2022 Decisions

USDC for the Eastern District of Pennsylvania

Inhibition Of Mitochondrial Complex I Reverses Notch1-Driven Metabolic Reprogramming In T-Cell Acute Lymphoblastic Leukemia., Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan Collins, Shannon Sweeney, Renu Pandey, Anna Skwarska, Shraddha Patel, Mathieu Tremblay, Vinitha Mary Kuruvilla, Antonio Cavazos, Mecit Kaplan, Marc O Warmoes, Diogo Troggian Veiga, Ken Furudate, Shanti Rojas-Sutterin, Andre Haman, Yves Gareau, Anne Marinier, Helen Ma, Karine Harutyunyan, May Daher, Luciana Melo Garcia, Gheath Al-Atrash, Sujan Piya, Vivian Ruvolo, Wentao Yang, Sriram Saravanan Shanmugavelandy, Ningping Feng, Jason Gay, Di Du, Jun J Yang, Fieke W Hoff, Marcin Kaminski, Katarzyna Tomczak, R Eric Davis, Daniel Herranz, Adolfo Ferrando, Elias J Jabbour, M Emilia Di Francesco, David T Teachey, Terzah M Horton, Steven Kornblau, Katayoun Rezvani, Guy Sauvageau, Mihai Gagea, Michael Andreeff, Koichi Takahashi, Joseph R Marszalek, Philip L Lorenzi, Jiyang Yu, Stefano Tiziani, Trang Hoang, Marina Konopleva

Faculty Research 2022

T-cell acute lymphoblastic leukemia (T-ALL) is commonly driven by activating mutations in NOTCH1 that facilitate glutamine oxidation. Here we identify oxidative phosphorylation (OxPhos) as a critical pathway for leukemia cell survival and demonstrate a direct relationship between NOTCH1, elevated OxPhos gene expression, and acquired chemoresistance in pre-leukemic and leukemic models. Disrupting OxPhos with IACS-010759, an inhibitor of mitochondrial complex I, causes potent growth inhibition through induction of metabolic shut-down and redox imbalance in NOTCH1-mutated and less so in NOTCH1-wt T-ALL cells. Mechanistically, inhibition of OxPhos induces a metabolic reprogramming into glutaminolysis. We show that pharmacological blockade of OxPhos combined with …

Matrix Distributors Inc V. National Association Of Boards

2022 Decisions

USDC for the District of New Jersey

Tyrone Martin V. Secretary Pennsylvania Departm

2022 Decisions

USDC for the Middle District of Pennsylvania

Educational Policy Committee Meeting – Open Session Packet 05/19/2022, Uc Hastings Board Of Directors

2022 Board of Directors Agenda and Materials

No abstract provided.

Finance Committee Meeting - Open Session Packet 05/19/2022, Uc Hastings Board Of Directors

2022 Board of Directors Agenda and Materials

No abstract provided.

Effects Of Administration Of A Growth Promoting Implant During The Suckling Phase Or At Weaning On Growth, Reproduction, And Ovarian Development In Replacement Heifers Grazing Native Range, Shelby L. Rosasco, Emily A. Melchior-Tiffany, Cierrah J. Kassetas, Shad H. Cox, Richard L. Dunlap, Jennifer A. Hernandez Gifford, Eric J. Scholljegerdes, Robert A. Cushman, Adam F. Summers

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Management strategies utilized during pre-breeding development of replacement heifers can impact fertility and the ovarian reserve. Angus- Hereford crossbred heifers (n = 233) were utilized over a 3-yr period to determine the effects of administration of a growth promoting implant at either branding or weaning on growth, reproduction, and ovarian development. Heifer calves were randomly assigned to one of three treatments: 1) nonimplanted controls (CON; n = 79), 2) implanted at approximately 2 mo of age (average calf age = 58 d) with Synovex-C (BIMP, n = 82), or 3) implanted at approximately 7 mo of age (average calf …

In Re: Reinard Smith

2022 Decisions

USDC for the Eastern District of Pennsylvania

Conscription In South Korea, Jennifer Rhee

Symposium Of University Research and Creative Expression (SOURCE)

South Korea has had a mandatory military service requirement for male South Korean citizens from the ages 18-28 since the 1950's- the government's response to accelerate the establishment of a stronger defense force during post cold-war times. The disposition of conscription has been changed multiple times since it's implementation and continues to be reexamined as South Korea progresses, but it still faces scrutiny and controversies as forced labor conventions are challenged and many young men will try to find exemptions from the obligation to serve their country for several years. This presentation will observe the history, reasoning, and future of …

The Need To Belong: Interweaving State History In Adult Esl To Support Culturally Responsive Teaching, Sandra Watkins

Master's Projects and Capstones

As an increasing variety of cultures is represented in our adult ESL classrooms, and there is a growing need for instructors to employ culturally responsive teaching methods to bridge the gap between students’ cultural backgrounds and the current curriculum and instructional practices being used in our community college noncredit classrooms. The existing cultural dissonance between the mainstream culture and their own may cause learners to internalize negative individual and group identities resulting in low expectations for life changes. Without understanding the relationship between your home and your host country, the history of the new place, or a sense of connection …

Investing In Human Futures: How Big Tech And Social Media Giants Abuse Privacy And Manipulate Consumerism, Brett Dembrow

University of Miami Business Law Review

Social media companies such as Facebook, Twitter, and Instagram originated with one seemingly innocent goal: “to bring the world closer together.”1 Now, these Big Tech giants own and operate some of the most powerful platforms in the world simply because of their unethical yet effective strategies to maintain their users’ attention. Social media companies have monetized the amount of time their users spend on their platforms by honing in on the individual preferences of each user and selling that access to advertisers. This heightened access to potential consumers and their preferences has become the most valuable marketing tool for digital …

Louis Henkin Memorial Lecture, Juan E. Mendez

University of Miami International and Comparative Law Review

No abstract provided.

Sound Familiar? Digital Sampling Is Taking Center Stage, Logan Zucchino

University of Miami Business Law Review

In 2018, Kendrick Duckworth, better known by his stage-name Kendrick Lamar, became the first non-classical or jazz musician to win the Pulitzer Prize in Music. Equally as surprising, the album contained a magnitude of digital sampling. As digital sampling has become more prevalent since the 1980’s, courts have differed on how to handle the issue. By 2016, the Sixth and Ninth Circuit Courts of Appeals established a circuit split on the issue, with one holding that unlicensed digital sampling is per se unlawful, and the other holding that a more lenient test is needed. Courts have continued to struggle with …

Japanese Gender Trouble In Revolutionary France: Ikeda Riyoko's Shōjo Manga The Rose Of Versailles, Saki Hirozane

Dissertations and Theses

Although traditional gender norms are reinforced by pop-culture media in Japan, some comics aimed primarily at female readers fight against those same gender norms. Shōjo manga (Japanese girls' comics) are no exception and have done so since their "revolution" in the 1970s. In the 1970s, a new wave of young female shōjo manga artists pioneered a different kind of girls' manga because they created new perspectives for their young female readers.

Ikeda Riyoko's Rose of Versailles (Berusaiyu no bara, 1972-73), set in Revolutionary-Era France, changed how Japanese women could see themselves in the 1970s. In Rose of Versailles …

Ftc V. Qualcomm And The Need To Reboot Antitrust Goals, Beatriz Del Chiaro Da Rosa

University of Miami Business Law Review

The antitrust community is facing a demanding question: Is antitrust enforcement ultimately about protecting consumers, competition, or both? This question has sparked debates about the ultimate goals of antitrust law. On one side of the debate, supporters of the consumer welfare standard; and on the other side, supporters of the Neo-Brandeisian standard of enforcement. At this crucial time in the debate of overarching antitrust goals, the Ninth Circuit’s holding in Federal Trade Commission v. Qualcomm Incorporated, one of the most important antitrust cases in the twenty-first century, poses many issues for the consumer welfare standard and antitrust enforcement in the …

How To Pay Off Hard Work, Juliette Hernandez

University of Miami Business Law Review

No abstract provided.

Brief Of Amicus Curiae Notre Dame Law School Religious Liberty Initiative, Megan M. Wold, John A. Meiser

Court Briefs

No. 22-cv-000067
Columbus City School District v. State of Ohio

Judge Jaiza N. Page

From the Summary of Argument

Under Count 4 of their complaint, the plaintiffs ask this Court to do something that it unquestionably may not: invalidate Ohio's longstanding EdChoice Scholarship Program on the theory that it violates the "no-funding" provision of Article VI, § 2 of the Ohio Constitution, which bars any "religious or other sect" from receiving "any part of the school funds of this state." See Compl. ¶¶ 142-52. Under both state and federal law, this Court must dismiss that claim.

“Sorry,” But I Didn’T Release It: How The Court’S Analysis Of The Fair Use Doctrine In Chapman V. Maraj Protects Innovation And Creativity In The Music Industry, Samantha Ross

University of Miami Business Law Review

The fair use doctrine is an important affirmative defense to copyright infringement when a particular use does not interfere with copyright law’s primary goal of promoting creativity for the public good. Artists and songwriters frequently experiment with copyrighted music without permission before seeking licensing approval from the original rights holders to “sample” or “replay” the work. In Chapman v. Maraj—a copyright infringement suit brought by Tracy Chapman against Nicki Minaj—the United States District Court for the Central District of California held that experimenting with a copyrighted musical composition for the purpose of creating a new work with an intent to …

Wmu Board Of Trustees Formal Session May 19, 2022, Wmu Board Of Trustees

WMU Board of Trustees Meetings

• Acceptance of the Agenda
• Remarks by the Chair
• Remarks by the President
• Public Comments Regarding Action Item

Action Items

• IF-1 Dunbar Hall Renovation Resolution

Big Data, Both Friend And Foe: The Intersection Of Privacy And Trade On The Transatlantic Stage, Gabrielle C. Craft

University of Miami International and Comparative Law Review

This Note analyzes the data privacy protection initiatives implemented by the European Union and the United States and their effects on international trade. As technology develops, the feasibility of data collection increases, allowing for the collecting of inconceivable amounts of data information. Consequently, this data includes personal information, thus implicating privacy concerns and the need for data privacy protection regulations. Data privacy focuses on the use and governance of personal data and how the data is gathered, collected, and stored. In 2018, the European Union enacted the General Data Protection Regulation (GDPR), which sets out highly stringent standards for how …

Comparative Laws In Public Health Unmasked, Christine Chasse

University of Miami International and Comparative Law Review

The COVID-19 pandemic lay bare the vulnerabilities of some countries’ public health responses and praise for others. Comparative law review in public health responses may glean lessons for the United States. For example, the United States had not had a pandemic of this magnitude in over a century and was reluctant to institute early masking policies. Meanwhile, the world raced for a COVID-19 vaccine. This begs the question of who will take the vaccine. Will—or can—governments force their citizens to be inoculated? Global comparisons in personal liberty, freedom, bodily autonomy, and how to parent intersect at the right to (or …

International Law & Covid-19 Symposium, Joseph Candelaria, Gita Howard, Tamar Ezer

University of Miami International and Comparative Law Review

The COVID-19 pandemic has sent shock waves through the international community, exposing systemic failures and highlighting injustices. At the same time, it has provided an opening to consider new approaches, including lessons for international law.
On April 12 and 16, 2021, the University of Miami School of Law International and Graduate Law Programs and Human Rights Clinic, in collaboration with the Human Rights Society, Health Law Association, Environmental Law Program, and University of Miami International and Comparative Law Review hosted a symposium on the impact of COVID-19 on international law. The International Law and COVID-19 Symposium specifically focused on the …

Gambling On Video Games: The Global Esports Betting Market And The Dawn Of Legalized Esports Gambling In The United States, Jake Bland

University of Miami International and Comparative Law Review

This Note compares eSports gambling regulations in the United States with regulations implemented in various foreign countries. eSports is a rapidly growing form of sport competition centered around video games. Video games have been a widely popular form of entertainment spanning the globe for many years. However, treating video games as a professional sport and form of monetized competition is a very recent phenomenon in the global mainstream market. Like traditional sports such as football and basketball, eSports have garnered significant attention in the gambling market. Sports betting has long been prevalent in the underworld of the United States, but …

Tiktok, Cfius, And The Splinternet, Jake T. Seiler

University of Miami International and Comparative Law Review

This note will discuss the role that the Committee on Foreign Investment in the United States (“CFIUS” or “the Committee”) has played in foreign relations and how it contributes to the balkanization of the internet today. The Committee is an interagency body that reviews foreign investments for potential national security threats. Recently, CFIUS has been in the spotlight for its role in the sale of TikTok, a cellphone app owned by a popular Chinese corporation, ByteDance. While much of CFIUS’ review in the past has been focused on Chinese-owned corporations, there is much debate about whether or not countries should …

Immunization And Indemnification: Rethinking The Us Approach To Liability Protections For Vaccine Manufacturers During The Covid-19 Pandemic, Samantha Topper Berns

University of Miami International and Comparative Law Review

This note analyzes the legal mechanisms in the United States that provide compensation for vaccine injuries sustained as a result of inoculation against pandemic viruses when a public health emergency has been declared. While the United States has an every-day compensation scheme that deters litigation by providing just compensation yet upholds the right of injured parties to seek damages in court, it has a special compensation scheme applicable to vaccines developed to address public health emergencies that bars litigation by effectively providing vaccine manufactures with complete indemnification and severely restricts the ability of injured parties to receive compensation. Meanwhile, in …

Utilisation Of Library Information Resources By Undergraduates Of Public University In Ogun State, Rahman Olorunleke Arowolo, B.A. Ajiboye, Samuel Kolawole Adio

Library Philosophy and Practice (e-journal)

The library has the singular function of collecting, organising, preserving, conserving and making information accessible to potential users in different formats. This study examined the correlation between utilisation of print and electronic resources by Undergraduates of Olabisi Onabanjo University, Ago-Iwoye and Tai solarin University, Ijagun, Ogun State, Nigeria. Structured questionnaire was used to obtain data from 380 students from the total population 39,256 of the undergraduates in the institutions, while for the qualitative data the researcher interviewed the Heads of Automation and Readers’ Services Units of the three universities studied. Data collected were analysed using descriptive statistics, frequencies, percentage, mean, …

Resume Research Questions Through The Seven Philosophical Foundations Of Communication, Michael W. Major

Faculty & Staff Scholarship

While there is no lack of peer-reviewed publications that focus on resumes, there is a lack of theory-based research in the genre. Most studies on resumes report observations rather than test theories to predict screener behaviors, and recent calls to action have advocated for more theory-based resume research. This paper answers the call and offers ways in which scholars can introduce theory into the existing body of knowledge in the resume genre by exploring research questions guided by the various philosophical foundations of the communication discipline. Future resume research should reference Craig’s constitutive metamodel that offers more than 250 communication …

178 Broadway Realty Corp. V. Charles

All Decisions

ERAP Case.

Eight-17 Assoc. Lp V. Cameron

All Decisions

ERAP case.

88 Ave. Realty De Llc V. Castro

All Decisions

No abstract provided.