Digital Commons Network^™

Preventing Spinal Muscular Atrophy Through The National Premarital Screening Program In Türkiye: An Economic Comparison With Treatment Costs, Gamze Dur, Gülcan Teci̇rli̇, Nurullah Okumuş

Turkish Journal of Medical Sciences

Background/aim: Spinal muscular atrophy (SMA) is a severe neuromuscular disorder with high treatment costs and significant psychosocial burden. In 2021, Türkiye launched a national premarital SMA carrier screening program integrated with in vitro fertilization (IVF) with preimplantation genetic testing (PGT) services for couples identified as carriers. This study aimed to compare the costs associated with the carrier screening and prevention program versus a no-screening (treatment-only) scenario.

Materials and methods: A cost comparison model was developed using data from the Turkish Statistical Institute, the Ministry of Health, and the Social Security Institution. The annual costs of SMA treatment (with nusinersen and …

A Study Of The Intellectual Property Rights Of Farmers With Special Reference To The Protection Of Plant Variety And The Farmers' Rights Act, 2001, Gomathi R Ms

Theses and Dissertations

Intellectual Property Rights (IPR) confer exclusive rights on individuals over the creations of their minds. Intellectual property is protected through patents, trademarks, copyrights, industrial designs, geographical indications, and other legal rights, enabling inventors to obtain economic benefits and legal recognition from their innovations. These rights provide exclusive usage for a prescribed period and have evolved significantly over the years, sharing similarities with ownership rights over tangible property. As intangible rights, IPR primarily consist of the property element and the object to which that property relates. Among the various forms of IPR, Plant Variety Protection (PVP) rights recognize the creativity and …

Defense Distributed V. Attorney General New Jersey

2026 Decisions

USDC for the District of New Jersey

Work-Life Balance And Occupational Stress: Moderating Factors Among African American Telecommunication Workers, Robert Charity

Walden Dissertations and Doctoral Studies

After the COVID-19 pandemic, remote call center employees faced intensified challenges in maintaining work-life balance (WLB) while experiencing elevated occupational stress (OS) levels. The purpose of this quantitative correlational study was to investigate the relationship between WLB and OS among African American (AA) call center professionals employed in the telecommunications industry, moderated by resilience (RS), gender, and generational age (GenAge). The theoretical framework included boundary theory, the job demands-control model, and resilience theory. The participants comprised 103 AA telecommunications call center professionals aged 28 to 65 in the southwestern United States. They completed the work-life balance scale, perceived occupational stress …

Francisco Merino-Angel V. Attorney General United States Of America

2026 Decisions

Agency

Clinical Outcome Of Extremity Arterial Injuries In The Modern Era, Ali̇ Kuşsan, Selçuk Coşkun, Alp Şener, Ferhat İçme, Pinar Köksal Coşkun, Gülhan Kurtoğlu Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Extremity arterial injuries (EAIs) present a significant clinical challenge due to the risk of limb ischemia, amputation, and mortality. This retrospective cohort study aimed to delineate the clinical course, treatment strategies, and patient outcomes following trauma-induced EAIs, and to identify independent predictors of adverse outcomes.

Materials and methods: Retrospectively analyzed were data from 168 consecutive patients with traumatic EAIs who underwent computed tomography angiography at a tertiary care center between 2019 and 2025. Data extracted from electronic medical records included demographics, injury mechanisms, clinical presentation, laboratory findings, imaging results, treatment modalities (primary repair, grafting, endovascular intervention, conservative management), and …

The Perk Signaling Pathway As A Marker Of The Unfolded Protein Response In Patients With Acute Myeloid Leukemia, Nergi̇z Erkut, Turhan Köksal, Seli̇m Demi̇r, Ahmet Menteşe, Özlen Balta, Mehmet Sönmez

Turkish Journal of Medical Sciences

Background/aim: The protein kinase RNA-like endoplasmic reticulum kinase (PERK) pathway plays a critical role in preventing the accumulation of misfolded or unfolded proteins within the endoplasmic reticulum. In this study, the role of the PERK signaling pathway was evaluated in newly diagnosed, treatment-naïve patients with acute myeloid leukemia (AML).

Materials and methods: Plasma levels of eukaryotic translation initiation factor 2-alpha kinase 3 (eIF2AK3), glucose-regulated protein 78 (GRP78), activating transcription factor 6 (ATF6), CCAAT/enhancer-binding protein homologous protein (CHOP), hypoxia-inducible factor-1 alpha (HIF-1α), and caspase 3 were measured by enzyme-linked immunosorbent assay in peripheral blood samples obtained from AML patients and healthy …

Defense Distributed V. Attorney General New Jersey

2026 Decisions

USDC for the District of New Jersey

Systematic Synthesis Of Crispr/Cas Applications For Enhancing Salt Tolerance In Crops: A Decade Of Progress And Challenges, Xindi Sun, Fusheng Wu, Zhuanzhuan Ma, Guohao Liang, Shumei Chen, Xutong Hu, Shugao Fan, Ying Zhao

School of Mathematical & Statistical Sciences Faculty Publications

Soil salinity is a major constraint on global crop productivity, driving the need for salt-tolerant varieties. While CRISPR-Cas genome editing offers targeted solutions for trait improvement, significant biological and technical bottlenecks limit its application in conferring salt stress resilience. This systematic summarizes findings from 83 peer-reviewed studies (2015–2024) employing CRISPR/Cas technologies to improve salt tolerance in five major crops (rice, wheat, maize, sorghum, barley). Our systematic review reveals that early single-gene edits achieved modest gains (30–50% Na⁺ exclusion) but often showed limited yield gains in field settings, potentially due to compensatory regulation and environmental variation. The literature suggests that multiplex …

No. 112 An Order Amending Executive Order 87 Regarding The Governor's Council For Judicial Appointments, Bill Lee

Executive Orders

No abstract provided.

No. 112 An Order Amending Executive Order 87 Regarding The Governor's Council For Judicial Appointments, Bill Lee

Executive Orders

No abstract provided.

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

Francisco Merino-Angel V. Attorney General United States Of America

2026 Decisions

Agency

Spartan Daily, February 12, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 10

Colonisation, Globalisation And A Pandemic: Developing Understandings Of Inclusive Education In Malaysia, Vicky Bamsey, Yee Ling Lee, Moses Samuel

School of Law, Humanities and Social Sciences

This is a theoretical paper that examines how colonisation, globalisation and a crisis such as the Covid-19 pandemic have had a significant influence on the development of inclusive education policy and practice in Malaysia. Drawing on the ideas of dependency from Farid Alatas, and Carol Bacchi’s focus on the identification of the underlying problem within policies, as well as Stephen Ball’s policy cycle, we highlight how global events have repercussions at a policy level now and into the future. This paper contributes to the wider inclusive education debate through the innovative use of these three different theoretical lenses, informed by …

Front Matter

Creative Nonfiction Magazine

No abstract provided.

The Writers In The Silos, Heidi Julavits

Creative Nonfiction Magazine

No abstract provided.

Netting The Future, Donna Seaman

Creative Nonfiction Magazine

No abstract provided.

The Death Of The Book, David Henry Sterry

Creative Nonfiction Magazine

No abstract provided.

Selling The House, Marianna De Marco Torgovnick

Creative Nonfiction Magazine

No abstract provided.

Insurance

Warren C. Cowen Papers

No abstract provided.

Contract

Warren C. Cowen Papers

No abstract provided.

Insurance

Warren C. Cowen Papers

No abstract provided.

Warranty Deed

Warren C. Cowen Papers

No abstract provided.

Then You’Ll Be Straight, Margaret Price

Creative Nonfiction Magazine

No abstract provided.

From “A Writer’S Life”, Gay Talese

Creative Nonfiction Magazine

No abstract provided.

Style-Preserved Inference Flow (Spif): Real-Time Style-Locked Image Generation Through Model Pruning And Latent Space Optimization, Douglass W. Sharp

Defensive Publications Series

This publication discloses Style-Preserved Inference Flow (SPIF), a system for real-time style-locked image generation that maintains consistent artistic style across frames at interactive rates. The core innovation is structural model pruning guided by style-consistency metrics rather than general image quality, producing compact single-purpose models that generate images in a specific artistic style at 60+ frames per second. Additional disclosed techniques include latent-space frame coherence (bootstrapping sequential frames from previous latent states, analogous to dirty-rectangle optimization in game rendering), composable latent object descriptors for real-time scene manipulation, and voice-driven continuous generation loops. Working prototypes demonstrate 3.35 FPS full-pipeline generation at 1024×1024 …

New Government Policies

Warren C. Cowen Papers

Summary of Veterans' Affairs Committee action.

New Law Passed

Warren C. Cowen Papers

Law passed by the House of Representatives to increase the compensation payable to service-connected disabled veterans.