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Mapping Per- And Polyfluoroalkyl Substances (Pfas) In South Carolina Surface Waters: Are There Hotspots?, Thomas C. Geiger Apr 2023

Mapping Per- And Polyfluoroalkyl Substances (Pfas) In South Carolina Surface Waters: Are There Hotspots?, Thomas C. Geiger

Senior Theses

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in consumer products for their unique chemical properties. PFAS compounds are resistant to water, oil, heat, and grease, making them useful for a wide variety of everyday items such as non-stick cooking pans, food packaging, electronics, carpets, upholstery, paints, adhesives, and personal care products.1 The resilient nature of PFAS has made these compounds immensely popular with consumers but has since been considered a potential environmental and public health hazard for their ability to bioaccumulate and for their stability in the environment. More than 6000 PFAS have been discovered in the …


Immunohistochemical Investigation Of Wwp1 Expression During Embryonic Heart Development And Its Implications For Cardiac Aging, Savannah L. Bowers Apr 2023

Immunohistochemical Investigation Of Wwp1 Expression During Embryonic Heart Development And Its Implications For Cardiac Aging, Savannah L. Bowers

Senior Theses

Cardiovascular disease is the leading cause of mortality globally, with the aging population being most vulnerable. Cardiomyocytes and cardiac fibroblasts mediate pathophysiological changes of cardiac aging including interstitial fibrosis, left ventricular hypertrophy, lethal arrhythmias, and eventual culmination in heart failure. Interestingly, subclinical congenital heart disease and hypertrophic cardiomyopathy, originating in embryonic development, induce accelerated cardiac aging. The diverse developmental origins of cardiac fibroblasts suggest that perturbations in gene expression within this heterogeneous cell population during embryonic heart development have significant consequences for cardiac aging. Previous studies implicate the E3 ubiquitin ligase WWP1, a post-translational regulatory protein, in accelerated cardiac aging. …


Fixing The System: A Comparative Review Of The United Kingdom, Germany, And United States’ Healthcare Systems And Lessons Learned For Potential Improvements In The United States, Jessica Goddard Apr 2023

Fixing The System: A Comparative Review Of The United Kingdom, Germany, And United States’ Healthcare Systems And Lessons Learned For Potential Improvements In The United States, Jessica Goddard

Senior Theses

In an effort to provide recommendations to the United States’ considerations of a universal healthcare system, this thesis analyzes the United States healthcare system alongside the sophisticated systems of the United Kingdom and Germany. Literature review and an analysis of 10 health outcomes and indicators guided the framework for a set of interview questions to be asked of healthcare professionals in all three countries. The interview response data was then organized and used to guide the suggested recommendations to the United States in its path towards universal healthcare. While a limited number of solutions could be provided given the time …


"Yes Mom, I'M Eating": Foodways Among An International Cohort, Tessa Sergile Apr 2023

"Yes Mom, I'M Eating": Foodways Among An International Cohort, Tessa Sergile

Senior Theses

This research demonstrates different ways an individual’s habits around food change when exposed to new environments. It uses a combination of first-person sources and existing literature to draw conclusions surrounding the patterns of change in food preparation and consumption. A series of interviews were conducted and recorded to collect the information used in the thesis. The interview participants were college-aged students who had spent 6 < months in a foreign country. Most were participants of the IBEA cohort of South Carolina, a program where students around the world came together as a group to study at multiple universities over two years. Interviews were based on an interview guide that was refined throughout the process. There were a total of 33 interviews, with participants hailing from six different countries. The results of the interviews demonstrated that individuals exhibited varying types of behavior based on their own viewpoints towards cooking and meals, as well as the environment they were exposed to during meal preparation. This information was used to create a matrix to classify individuals based on their inspirations in cooking, and their use of home habits. The results lead to an additional category of “Unconscious Preparation” being proposed to the existing subcategories of food preparation. Further analysis of the data collected is also encouraged. This research adds depth to the present literature since it deals with individuals who are in foreign environments for the short-term, before moving away. Current literature mainly focuses on immigrants who move away from their homeland permanently (Brown and Mussell, 1984; Goode, Theophano and Curtis, 1984; Kalčik, 1984; Singer, 1984). It adds a new consideration to how we approach mealtimes when we are in a foreign environment and helps define different approaches that people may take when preparing food away from where they grew up. These findings could be used for other students studying abroad to better determine how their mealtime habits may change. There is also literature in Gottlieb and Rossi (1961), which describes similar effects in the military, whose style of travel and living is similar to that of an international student, meaning the results could also be interesting to the government when trying to plan for meals served to active-duty personnel abroad.


Counting Elliptic Curves With A Cyclic M-Isogeny Over Q, Grant S. Molnar Apr 2023

Counting Elliptic Curves With A Cyclic M-Isogeny Over Q, Grant S. Molnar

Dartmouth College Ph.D Dissertations

Using methods from analytic number theory, for m > 5 and for m = 4, we obtain asymptotics with power-saving error terms for counts of elliptic curves with a cyclic m-isogeny up to quadratic twist over the rational numbers. For m > 5, we then apply a Tauberian theorem to achieve asymptotics with power saving error for counts of elliptic curves with a cyclic m-isogeny up to isomorphism over the rational numbers.


The Bridwell Quarterly. Issue 19, Spring 2023, Michelle Ried Apr 2023

The Bridwell Quarterly. Issue 19, Spring 2023, Michelle Ried

Bridwell Library Publications

No abstract provided.


A Gravity Model Integrating Land-Use And Transportation Policies For Sustainable Development: Case Study Of Fresno, California, Chih-Hao Wang, Na Chen Apr 2023

A Gravity Model Integrating Land-Use And Transportation Policies For Sustainable Development: Case Study Of Fresno, California, Chih-Hao Wang, Na Chen

Mineta Transportation Institute

The idea of urban compaction has been long proposed and promoted to address the problem of urban sprawl in many American cities. However, there are still rare successful cases of such implementation in the United States. This study uses a classic gravity model, TELEM (Transpiration, Economic, and Land-Use Model) to examine to what extent a land-use or transportation policy must be regulated to make the urban compaction occur in a typical auto-dependent city—Fresno, California. Five scenarios are considered (BL, L1, L2, T1, and T2), in which the baseline (BL) is a natural growth scenario. Without any policy interventions, the city …


Using Thermal Remote Sensing To Quantify Impact Of Traffic On Urban Heat Islands During Covid, My-Thu Tran, Bo Yang Apr 2023

Using Thermal Remote Sensing To Quantify Impact Of Traffic On Urban Heat Islands During Covid, My-Thu Tran, Bo Yang

Mineta Transportation Institute

A three-month lockdown in the U.S. at the beginning of the COVID-19 outbreak in 2020 greatly reduced the traffic volume in many cities, especially large metropolitan areas such as the San Francisco Bay Area. This research explores the impact of transportation on climate change by using remote sensing technology and statistical analysis during the COVID-19 lockdown. Using thermal satellite data, this research measures the intensity of the urban heat island, the main driver for climate change during the urbanization process. The research team acquired morning and afternoon MODIS data in the same periods in 2019 before the pandemic and 2020 …


The Future Of Water In Mena Is At Stake, Malak Altaeb Apr 2023

The Future Of Water In Mena Is At Stake, Malak Altaeb

Faculty Journal Articles

The MENA region, one of the driest in the world, is facing unprecedented water management challenges due to the effects of climate change.


An Improvement Method For Massive Multiple-Input Multiple-Output Mimo System Deployment, Lijun Han, Ling Weay Ang, Sellappan Palaniappan Apr 2023

An Improvement Method For Massive Multiple-Input Multiple-Output Mimo System Deployment, Lijun Han, Ling Weay Ang, Sellappan Palaniappan

Malaysian Journal of Computing (MJoC)

This paper proposes a novel method for deploying massive multiple-input multiple-output (MIMO) systems, an essential component of next-generation wireless networks. The proposed method is designed to address the challenges of deploying MIMO systems in practical scenarios, including the selection of optimal antenna configurations and the need for efficient use of available resources. The method uses advanced machine learning techniques to optimize the deployment of MIMO systems, considering a variety of factors such as channel characteristics, interference, and network topology. The results of the systematic review show that the combination of channel coding technology and antenna diversity technology can significantly increase …


A Candidate Runaway Supermassive Black Hole Identified By Shocks And Star Formation In Its Wake, Pieter Van Dokkum, Imad Pasha, Maria Luisa Buzzo, Stephanie Lamassa, Zili Shen, Michael A. Keim, Roberto Abraham, Charlie Conroy, Shany Danieli, Kaustav Mitra, Daisuke Nagai, Priyamvada Natarajan, Aaron J. Romanowsky, Grant Tremblay, C. Megan Urry, Frank C. Van Den Bosch Apr 2023

A Candidate Runaway Supermassive Black Hole Identified By Shocks And Star Formation In Its Wake, Pieter Van Dokkum, Imad Pasha, Maria Luisa Buzzo, Stephanie Lamassa, Zili Shen, Michael A. Keim, Roberto Abraham, Charlie Conroy, Shany Danieli, Kaustav Mitra, Daisuke Nagai, Priyamvada Natarajan, Aaron J. Romanowsky, Grant Tremblay, C. Megan Urry, Frank C. Van Den Bosch

Faculty Research, Scholarly, and Creative Activity

The interaction of a runaway supermassive black hole (SMBH) with the circumgalactic medium (CGM) can lead to the formation of a wake of shocked gas and young stars behind it. Here we report the serendipitous discovery of an extremely narrow linear feature in Hubble Space Telescope (HST) Advanced Camera for Surveys images that may be an example of such a wake. The feature extends 62 kpc from the nucleus of a compact star-forming galaxy at z = 0.964. Keck Low-resolution Imaging Spectrometer spectra show that the [O iii]/Hβ ratio varies from ∼1 to ∼10 along the feature, indicating a mixture …


Incorporating Crash Severity And Continuous Improvement Of Shift, Reginald Souleyrette, Riana Tanzen, Teng Wang Apr 2023

Incorporating Crash Severity And Continuous Improvement Of Shift, Reginald Souleyrette, Riana Tanzen, Teng Wang

Kentucky Transportation Center Research Report

The Strategic Highway Investment Formula for Tomorrow (SHIFT) is the Kentucky Transportation Cabinet's data-informed approach for comparing capital improvement projects and prioritizing limited transportation funds. SHIFT 2022 incorporates advancements in methods and flexibility. This project revises the SHIFT crash data safety metric. The crash data safety metric from the previous version of SHIFT was excess expected crashes (EECs). It is computed using the total number of crashes of all severities. Locations with a higher proportion of severe (fatal and injury) crashes received the same weight as locations with an equal number of property damage only crashes. This project redefines the …


Incorporating Variability In Kytc Planning And Project Development, Reginald Souleyrette, Teng Wang, Riana Tanzen, Arnold Stromberg Apr 2023

Incorporating Variability In Kytc Planning And Project Development, Reginald Souleyrette, Teng Wang, Riana Tanzen, Arnold Stromberg

Kentucky Transportation Center Research Report

Transportation planning and design decisions are typically made using point estimates of traffic and safety measures. This report addresses the uncertainty of data used to make these decisions. It focuses on two data elements — project safety ratings and volume estimates from traffic counts. For safety ratings, the Kentucky Transportation Cabinet’s Strategic Highway Investment Formula for Tomorrow (SHIFT) crash history score is used as a case study. Confidence intervals are developed for the Cabinet’s new safety metric, which incorporates estimates of future crashes by severity as well as excess expected crashes above safety goals. For traffic counts, the report develops …


The Exigency And How To Improve And Implement International Humanitarian Legislations More Advantageously In Times Of Both Cyber-Warfare And Cyberspace, Shawn J. Lalman Apr 2023

The Exigency And How To Improve And Implement International Humanitarian Legislations More Advantageously In Times Of Both Cyber-Warfare And Cyberspace, Shawn J. Lalman

Doctoral Dissertations and Master's Theses

This study provides a synopsis of the following topics: the prospective limiters levied on cyber-warfare by present–day international legislation; significant complexities and contentions brought up in the rendering & utilization of International Humanitarian Legislation against cyber-warfare; feasible repercussions of cyber-warfare on humanitarian causes. It is also to be contended and outlined in this research study that non–state actors can be held accountable for breaches of international humanitarian legislation committed using cyber–ordnance if sufficient resources and skill are made available. It details the factors that prosecutors and investigators must take into account when organizing investigations into major breaches of humanitarian legislation …


Social And Linguistic Marginalization, And The Question Of ‘Standard’: An Analysis And Translation Of Giulio Cesare Cortese’S La Vaiasseide, Lina R. Marsella , '23 Apr 2023

Social And Linguistic Marginalization, And The Question Of ‘Standard’: An Analysis And Translation Of Giulio Cesare Cortese’S La Vaiasseide, Lina R. Marsella , '23

Senior Theses, Projects, and Awards

No abstract provided.


Exploring Media Representations Of Covid-19 Vaccine Hesitancy In South Africa, Elizabeth Gallagher , '23 Apr 2023

Exploring Media Representations Of Covid-19 Vaccine Hesitancy In South Africa, Elizabeth Gallagher , '23

Senior Theses, Projects, and Awards

No abstract provided.


“Vulnerable” And “At Risk”?: Confronting Lgbtq+ Youth Mental Health Through A Digital Ethnography Of Queertok, Nicole Daly , '23 Apr 2023

“Vulnerable” And “At Risk”?: Confronting Lgbtq+ Youth Mental Health Through A Digital Ethnography Of Queertok, Nicole Daly , '23

Senior Theses, Projects, and Awards

No abstract provided.


Vulnerability During The Pandemic And The Disruption Of The Medical Gaze, Yeh Seo Jung , '23 Apr 2023

Vulnerability During The Pandemic And The Disruption Of The Medical Gaze, Yeh Seo Jung , '23

Senior Theses, Projects, and Awards

No abstract provided.


Care For The Land: Restoration As Interspecies Care Labor And Emergent Activism At The Hawaiian Fishpond-Scape, Cynthia Ruimin Shi , '23 Apr 2023

Care For The Land: Restoration As Interspecies Care Labor And Emergent Activism At The Hawaiian Fishpond-Scape, Cynthia Ruimin Shi , '23

Senior Theses, Projects, and Awards

In the last two decades, environmental NGOs on the islands of Hawai’I have been leading efforts to restore traditional land practices and foodways, among them fishpond, or loko i’a, which are traditional aquaculture infrastructures that ensure a stable production of fish protein. This ethnographic study of loko i’a restoration projects is informed by four months of fieldwork grounded in participant observation at Paepae O He’eia, a non-profit organization on the windward side of O’ahu heading the restorative effort at He’eia fishpond.

My thesis addresses the ethics of care, labor, and Indigenous worldmaking emerging from ecological and cultural restoration of fishponds …


“Dancing With [Philly’S] Ghosts”: Recycled Materials And Meanings At An Artists’ Residency, Gabriel D. Straus , '23 Apr 2023

“Dancing With [Philly’S] Ghosts”: Recycled Materials And Meanings At An Artists’ Residency, Gabriel D. Straus , '23

Senior Theses, Projects, and Awards

What’s at stake in people’s relationships with objects? I examine this question based on two months of in-depth participant observation and twelve semi-structured interviews with artists from RAIR, an artist residency at a Philadelphia dump, where artists make work out of the discarded material fabric of a gentrifying, deindustrializing city (read: demolished buildings/dead peoples’ stuff). Building on the work of Karen Barad, a physicist-turned-philosopher who outlines an “onto epistemology” based on quantum mechanics, I explore how objects and people “intra-act” at RAIR to refigure time, reshape the city, and redefine the human. I demonstrate how a Baradian agential realist reading …


Assessing The Total Economic Value Of Parks In Kalamazoo County, Samuel Herman Ayivi Apr 2023

Assessing The Total Economic Value Of Parks In Kalamazoo County, Samuel Herman Ayivi

Masters Theses

Urban parks and green spaces have become an important part of the urban ecosystems in recent years, and there is growing evidence on the positive relationship between having green spaces and good health. Indeed, access to urban parks is part of the United Nation’s Sustainable Development goals (Goal 11 target 7). In recent years, these parks and green spaces have become a subject of development pressures because of the inability of planners and researchers to clearly articulate the value of these parks. The Total Economic Value Framework (TEVF) situates resources (Parks and green spaces in this case) in the minds …


Human Frailty, Unbreakable Victims And Asylum, Rebecca Sharpless, Kristi E. Wintermeyer Apr 2023

Human Frailty, Unbreakable Victims And Asylum, Rebecca Sharpless, Kristi E. Wintermeyer

Articles

This article analyzes the asylum decisions of immigration agencies and federal appellate courts and demonstrates that the case law driven standard for persecution is out of step with the original meaning of the term, international law standards, and contemporary understanding of how human beings experience physical and mental harm. Medical and psychological evidence establishes that even trauma at the lower end of the spectrum of severity can inflict lasting and debilitating effects on people's health. Yet over the last three decades, virtually no court decisions have decreased the showing of harm needed to establish persecution. To the contrary, courts have …


How Law Schools Can Fight For Fearless Speech, Mary Anne Franks Apr 2023

How Law Schools Can Fight For Fearless Speech, Mary Anne Franks

Articles

No abstract provided.


Gender And Sexuality In Desperate Housewives, Berkley Smith Apr 2023

Gender And Sexuality In Desperate Housewives, Berkley Smith

Honors Theses

No abstract provided.


Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb Apr 2023

Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb

Saudi Medical Journal

Objectives: To determine the distinctive clinical and pathological characteristics and outcomes of MF in a Saudi population. Methods: We conducted a retrospective analysis of all MF cases diagnosed clinically with pathological confirmation at King Abdulaziz Medical City in Riyadh from January 2016 to July 2022. Variables include demographical, clinical, and pathological MF traits and disease outcomes. Results: A sum of 73 patients were enrolled. The mean age was 44 years. The female-to-male ratio was 1.3:1. The mean duration between cutaneous manifestations and MF diagnosis was 33 months (2.7 years). Classic MF was the most common variant (60.3%), followed by hypopigmented …


Differentiating Strict Products Liability’S Cost-Benefit Analysis From Negligence, Paul F. Rothstein, Ronald J. Coleman Apr 2023

Differentiating Strict Products Liability’S Cost-Benefit Analysis From Negligence, Paul F. Rothstein, Ronald J. Coleman

Georgetown Law Faculty Publications and Other Works

Dangerous products may give rise to colossal liability for commercial actors. Indeed, in 2021, the U.S. Supreme Court denied certiorari in Johnson & Johnson v. Ingham, permitting a more than two billion dollar products liability damages award to stand. In his dissenting opinion in another recent products liability case, Air and Liquid Systems Corp. v. DeVries, Justice Gorsuch declared that “[t]ort law is supposed to be about aligning liability with responsibility.” However, in the products liability context, there have been ongoing debates concerning how best to set legal rules and standards on tort liability. Are general principles of …


The Global Health Architecture: Governance And International Institutions To Advance Population Health Worldwide, Lawrence O. Gostin, Eric A. Friedman, Alexandra Finch Apr 2023

The Global Health Architecture: Governance And International Institutions To Advance Population Health Worldwide, Lawrence O. Gostin, Eric A. Friedman, Alexandra Finch

Georgetown Law Faculty Publications and Other Works

Policy Points Global health institutions and instruments should be reformed to fully incorporate the principles of good health governance: the right to health, equity, inclusive participation, transparency, accountability, and global solidarity. New legal instruments, like International Health Regulations amendments and the pandemic treaty, should be grounded in these principles of sound governance. Equity should be embedded into the prevention of, preparedness for, response to, and recovery from catastrophic health threats, within and across nations and sectors. This includes the extant model of charitable contributions for access to medical resources giving way to a new model that empowers low- and middle-income …


Revisiting Tocqueville's American Woman, Christine Dunn Henderson Apr 2023

Revisiting Tocqueville's American Woman, Christine Dunn Henderson

Research Collection College of Integrative Studies

This paper revisits Tocqueville’s famous portrait of the American female, which begins with assertions of her equality to males but ends with her self-cloistering in the domestic sphere. Taking a cue from Tocqueville’s extended sketch of the “faded” pioneer wife in “A Fortnight in the Wilderness” and drawing connections to Tocqueville’s criticisms of the division of industrial labor, I argue that the American girl’s ostensibly free choice to remove herself from public life is not an act of freedom. Rather, it is a manifestation of a particular type of unfreedom that reveals underappreciated connections between the two great dangers about …


Rage Inhibitors In Neurodegenerative Diseases, V. Prakash Reddy, Puspa Aryal, Pallavi Soni Apr 2023

Rage Inhibitors In Neurodegenerative Diseases, V. Prakash Reddy, Puspa Aryal, Pallavi Soni

Chemistry Faculty Research & Creative Works

Nonenzymatic Reactions of Reducing Sugars with Primary Amino Groups of Amino Acids, Proteins, and Nucleic Acids, Followed by Oxidative Degradations Would Lead to the Formation of Advanced Glycation Endproducts (AGEs). the AGEs Exert Multifactorial Effects on Cell Damage Leading to the Onset of Neurological Disorders. the Interaction of AGEs with the Receptors for Advanced Glycation Endproducts (RAGE) Contribute to the Activation of Intracellular Signaling and the Expression of the Pro-Inflammatory Transcription Factors and Various Inflammatory Cytokines. This Inflammatory Signaling Cascade is Associated with Various Neurological Diseases, Including Alzheimer's Disease (AD), Secondary Effects of Traumatic Brain Injury (TBI), Amyotrophic Lateral Sclerosis …


Due Process Discontents In Mass-Tort Bankruptcy, J. Maria Glover Apr 2023

Due Process Discontents In Mass-Tort Bankruptcy, J. Maria Glover

Georgetown Law Faculty Publications and Other Works

No abstract provided.