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Articles 99331 - 99360 of 819536
Full-Text Articles in Entire DC Network
Science Alive, Adam Sadik, Pranav Madadi, Mahalaxmi Some, Lohita Sunkara, Ashley Abad, Lickchina Jeanlis
Science Alive, Adam Sadik, Pranav Madadi, Mahalaxmi Some, Lohita Sunkara, Ashley Abad, Lickchina Jeanlis
Trick to the Treat of Internships and Research
Through the Science Alive outreach program, we work to bring the excitement of hands-on learning to grade-school children and the entire community. Science Alive promotes science education and interaction between the college and grade school community as “science buddies”. Group leaders can earn Science Alive internship credit and serve as volunteers with Broward County public schools. There are a variety of ways NSU students are involved in this internship program. We have a regular schedule of leading students once per week on Friday afternoons at Nova Blanche Elementary through NSU student-led activities to explore science. We also have been building …
Teaching Trauma Theory And Practice In Counselor Education: A Multiple Case Study, Charmayne R. Adams, Casey A. Barrio Minton, Jennifer Hightower
Teaching Trauma Theory And Practice In Counselor Education: A Multiple Case Study, Charmayne R. Adams, Casey A. Barrio Minton, Jennifer Hightower
Teaching and Supervision in Counseling
Teaching about trauma theory and practice is an integral part of counselor preparation. The purpose of this multiple case study was to understand how counselor educators (CEs) designed and facilitated significant learning experiences regarding trauma theory and practice. The researchers aimed to answer two research questions (1.) how do CEs choose which content to address in trauma courses and (2.) which teaching methods do CEs use to facilitate significant learning experiences in trauma courses? The study participants were three CEs teaching trauma courses in multiple formats (face-to-face, online, and hybrid) in CACREP programs. The results indicated that instructors faced unique …
Exploring The Relationship Between The Supervisory Alliance And The Development Of Reflexive Self-Awareness: A Mixed Methods Approach, Alexandre Brien, Réginald Savard, Cynthia Bilodeau, Patricia Dionne
Exploring The Relationship Between The Supervisory Alliance And The Development Of Reflexive Self-Awareness: A Mixed Methods Approach, Alexandre Brien, Réginald Savard, Cynthia Bilodeau, Patricia Dionne
Teaching and Supervision in Counseling
The study used embedded design to explore the relationship between alliance and perceived change in reflexive self-awareness in graduate trainees following counseling and psychotherapy programs (n = 48). Linear regression analyses were used to measure the predictive value of alliance on the development of supervisees' reflexive awareness. Qualitative reflexive thematic analysis was also conducted on critical incident reports of supervisees who perceived low vs strong alliances to gain greater in-depth understanding of the quantitative data. Results showed that the alliance does not directly predict observed changes in reflexive awareness. While alliance was found to create favorable conditions to support the …
Using The Five Ps: Conceptualizing Covid-19-Related Mental Health Concerns, Christine D. Gonzales-Wong, Scott Peters
Using The Five Ps: Conceptualizing Covid-19-Related Mental Health Concerns, Christine D. Gonzales-Wong, Scott Peters
Teaching and Supervision in Counseling
The COVID-19 pandemic has resulted in rising mental health concerns. As individuals experience loneliness, anxiety, and depression related to the pandemic, counselors-in-training navigate their treatment of clients while also living through the pandemic and its polarization. The authors present the Five Ps, a case conceptualization model that supervisors can use to help beginning counselors consider the history and context of the presenting concerns of clients, in addition to utilizing clients’ strengths in treatment. The authors provide a case illustration using the Five Ps in a supervision setting and discuss implications for supervision and future research.
Ciprofloxacin-Induced Peripheral Neuropathy: A Case Report, Alexander Refaeian, Eric L. Vest, Michael Schmidt, Jorge D. Guerra, Mohd N. Refaei, Michael Refaeian, Ryan A. Floresca, Manouchehr Refaeian
Ciprofloxacin-Induced Peripheral Neuropathy: A Case Report, Alexander Refaeian, Eric L. Vest, Michael Schmidt, Jorge D. Guerra, Mohd N. Refaei, Michael Refaeian, Ryan A. Floresca, Manouchehr Refaeian
HCA Healthcare Journal of Medicine
Introduction
Fluoroquinolones, a class of antibiotics, are commonly employed in the treatment of a wide array of bacterial infections. Recognized for their effectiveness against a broad spectrum of pathogens, fluoroquinolones have played a pivotal role in managing conditions like urinary tract infections and respiratory diseases. Nevertheless, their usage is not without contention due to their association with a variety of adverse effects, including tendon rupture and the less frequently reported issue of peripheral neuropathy.
Case Presentation
We present the case of a 42-year-old male who developed peripheral neuropathy several days after completing a 10-day course of ciprofloxacin for gastroenteritis. The …
A Retrospective Cohort Study Assessing The Impact Of Statin Therapy On Hospital Length Of Stay And Inpatient Mortality In Covid-19 Patients, Huy V. Ho, Hamish Patel, Mohammed Ahmed, Ahmed Eddib, Fagunkumar Modi, Domenick Sorresso, Rahul Mhaskar, David Phrathep, Olugbenga Oyesanmi
A Retrospective Cohort Study Assessing The Impact Of Statin Therapy On Hospital Length Of Stay And Inpatient Mortality In Covid-19 Patients, Huy V. Ho, Hamish Patel, Mohammed Ahmed, Ahmed Eddib, Fagunkumar Modi, Domenick Sorresso, Rahul Mhaskar, David Phrathep, Olugbenga Oyesanmi
HCA Healthcare Journal of Medicine
Background
Coronaviruses, known for their crown-like appearance, cause mild gastrointestinal and respiratory diseases. Some cause outbreaks of respiratory diseases, most recently, SARS-CoV-2, the coronavirus disease 2019 (COVID-19). Individuals with COVID-19 are reported to be in both arterial and venous prothrombotic states. In addition to a lipid-lowering effect, statin also has an anti-inflammatory effect, which addresses one of the underlying causes of thrombosis. An in-silico study revealed that statins could directly interact with the main protease enzyme of SARS-CoV-2 and prevent infectivity. Due to these pleiotropic properties, statins may positively impact the outcome of hospitalized patients with COVID-19 infections.
Methods
A …
Atrial Fibrillation: Rate Versus Rhythm Control, Carlos E. Vargas, Mina Bhatnagar, Haris Ahmed, Michael G. Flynn, Thomas Alexander
Atrial Fibrillation: Rate Versus Rhythm Control, Carlos E. Vargas, Mina Bhatnagar, Haris Ahmed, Michael G. Flynn, Thomas Alexander
HCA Healthcare Journal of Medicine
Atrial fibrillation (AF) remains the most common arrhythmia worldwide and is expected to affect approximately 12 million individuals in the United States alone by 2030. Thromboembolic events remain a feared complication of AF and should be treated and risk-stratified utilizing the CHA₂DS₂-VASc scoring system. Other complications of AF span a wide spectrum from impaired quality of life (QoL) to an increase in all-cause mortality. Rate control strategies consist of controlling the ventricular rate and have been shown to be a safe and effective strategy for asymptomatic AF patients. In patients who are plagued with symptoms leading to impaired QoL or …
Student's Interest In Penilik As Sustainable Development Extracurricular Program To Support Agricultural Awareness, Mely Yani, Syifa Qalbiyatul Layyinah, Ince Raudhiah Zahra, Annie Satriani Achwani, Riandi Riandi, Rini Sholihat, Amprasto Amprasto
Student's Interest In Penilik As Sustainable Development Extracurricular Program To Support Agricultural Awareness, Mely Yani, Syifa Qalbiyatul Layyinah, Ince Raudhiah Zahra, Annie Satriani Achwani, Riandi Riandi, Rini Sholihat, Amprasto Amprasto
Jurnal Inovasi Pendidikan IPA
This study is a descriptive study that aims to describe the implementation of the PENILIK (Pasukan Petani Cilik) Program and find out students' interest in the program to support the agricultural awareness of students. PENILIK is an extracurricular program in regenerative agriculture in a school environment that focuses on training in farming competencies, which has several stages, such as identification, analysis, implementation, and reflection. This program is an effort to implement the value of education sustainable development to increase students' interest and awareness in the agricultural area. Student's response was taken from a questionnaire given to 26 extracurricular members who …
Development Of Mangrove Ecosystem E-Encyclopedia As A Reference Source To Improve Information Literacy Skills And Environmental Care Attitudes Of Students, Ratminingsih Ratminingsih, Agung Wijaya Subiantoro
Development Of Mangrove Ecosystem E-Encyclopedia As A Reference Source To Improve Information Literacy Skills And Environmental Care Attitudes Of Students, Ratminingsih Ratminingsih, Agung Wijaya Subiantoro
Jurnal Inovasi Pendidikan IPA
This study aims to produce a development product that is feasible and effective to use for science learning in schools. The product developed is an e-encyclopedia of mangrove ecosystems. This study uses the Research and Development (R&D) model developed by Borg & Gall. The subjects of the limited trial consisted of 15 students of class VII. In comparison, the field trial consisted of 52 students from VII-G and VII-E of SMP IT Abu Bakar Yogyakarta. The data collection instruments included interviews, field observations, information literacy evaluation questions, and student environmental care attitude questionnaires. The field trial design used a pretest-posttest …
The Effect Of The Pjbl-Stem Model On Students' Critical Thinking Ability In Science Learning, Fintya Herlita, Sri Yamtinah, Icha Kurnia Wati
The Effect Of The Pjbl-Stem Model On Students' Critical Thinking Ability In Science Learning, Fintya Herlita, Sri Yamtinah, Icha Kurnia Wati
Jurnal Inovasi Pendidikan IPA
This study aims to prove the effectiveness of the PjBL-STEM model on students' critical thinking ability in science learning. This research is a quasi-experimental study with a pretest-posttest control group design. The experimental class in this research received the treatment of the PjBL-STEM model, and the control class received the treatment of the PjBL model. The research population was class VIII students of SMP Negeri 1 Dukun for the 2022/2023 academic year, which consisted of six classes. Meanwhile, the research sample was selected using a cluster random sampling technique, with class VIII E as the experimental class and class VIII …
Divulging Two Decades Of Multimedia Applications In Biology Education, Khairul Hafezad Abdullah
Divulging Two Decades Of Multimedia Applications In Biology Education, Khairul Hafezad Abdullah
Jurnal Inovasi Pendidikan IPA
Biology is an indispensable component of Science, Technology, Engineering, and Mathematics (STEM) education. Accordingly, effective biology teaching necessitates multimedia to assist students in fathoming complex scientific themes. This study aims to scrutinise the bibliometrics of preceding publications on multimedia applications in biology education from the Scopus and Web of Science databases. This study explores descriptive publishing patterns and the emergence of academic discourse about multimedia applications in biology education using ScientoPy and VOSviewer. The results reveal publications on this topic have been volatile, with less than ten publications in both databases. The United States has bested others as the most …
The Development Of Science E-Modules In Junior High Schools Integrated With Al-Qur'an Verses And Assisted By Virtual Simulations On The Subject Of Vibration, Waves And Sound, Niki Dian Permana, Cahaya Pitri Ramadan, Muhammad Ilham Syarif, Ira Mahartika, Rini Setyaningsih, Firmanul Catur Wibowo
The Development Of Science E-Modules In Junior High Schools Integrated With Al-Qur'an Verses And Assisted By Virtual Simulations On The Subject Of Vibration, Waves And Sound, Niki Dian Permana, Cahaya Pitri Ramadan, Muhammad Ilham Syarif, Ira Mahartika, Rini Setyaningsih, Firmanul Catur Wibowo
Jurnal Inovasi Pendidikan IPA
This research aims to produce junior high school science teaching materials in the form of e-modules that are integrated with verses from Al-Qur'an and assisted by virtual simulations on the subject of vibrations, waves and sound. The research method used is development research (R & D) which is adapted from the Borg and Gall development model. The stages of development research carried out are research and information collecting, planning, developing preliminary product, preliminary field testing, and main product revision. Data collection was carried out using questionnaires given to students, material experts, teaching materials experts, science-Al Qur'an integration experts and science …
Effects Of Mind Mapping And Visual Imagery Instruction Strategies On Senior Secondary Schools Students' Scientific Attitude To Mechanics In Ekiti State Of Nigeria, Edidiong E. Ukoh, Alaba Lawrence Aladejana
Effects Of Mind Mapping And Visual Imagery Instruction Strategies On Senior Secondary Schools Students' Scientific Attitude To Mechanics In Ekiti State Of Nigeria, Edidiong E. Ukoh, Alaba Lawrence Aladejana
Jurnal Inovasi Pendidikan IPA
The study examined the effects of visual imagery and mind mapping strategies on physics students' scientific attitude to mechanics in Ekiti state, Nigeria. The study adopted 3 X 1 pretest-posttest control group quasi experimental research design. Eight senior secondary schools were be purposively selected for the experimental groups, while four schools were purposively selected for the control group. This made a total of twelve schools that were selected from twelve local government areas across all the three senatorial districts of Ekiti state for the study. A total number of two hundred and forty six physics students from the selected schools …
The Effectiveness Of The Phet-Assisted Creative Problem Solving Model On Students' Creative Thinking Abilities And Cognitive Learning Outcomes, Liyana Putri Yani, Arif Widiyatmoko
The Effectiveness Of The Phet-Assisted Creative Problem Solving Model On Students' Creative Thinking Abilities And Cognitive Learning Outcomes, Liyana Putri Yani, Arif Widiyatmoko
Jurnal Inovasi Pendidikan IPA
This research aims to determine the effectiveness of the PhET-assisted creative problem solving model on creative thinking abilities and student learning outcomes in vibration, wave and sound materials. In this research, the samples taken were determined based on the characteristics of the two classes which were almost the same (homogeneous). The characteristics used are the average UAS scores of two classes which are close to the same and the science teacher who teaches in the same class. The sample chosen was class VIII with class A as the control class and class B as the experimental class with a total …
Development Of Augmented Reality (Ar) Learning Media To Increase Student Motivation And Learning Outcomes In Science, Ilham Widia Yusa, Ana Yuniasti Retno Wulandari, Badrud Tamam, Irsad Rosidi, Mochammad Yasir, Achmad Yusuf Bagus Setiawan
Development Of Augmented Reality (Ar) Learning Media To Increase Student Motivation And Learning Outcomes In Science, Ilham Widia Yusa, Ana Yuniasti Retno Wulandari, Badrud Tamam, Irsad Rosidi, Mochammad Yasir, Achmad Yusuf Bagus Setiawan
Jurnal Inovasi Pendidikan IPA
This research aims to 1) develop AR learning media regarding the interaction of living things and the environment, 2) determine the feasibility and response to AR media, and 3) determine differences in students' motivation and science learning outcomes before and after implementing AR media. AR-based mobile application. The study of AR media development uses the Waterfall development model which consists of 5 stages, namely analysis, design, code, testing, and maintenance. In-depth research data collection techniques use observation sheets, interview guides, media expert and material expert validation questionnaires, student response questionnaires as well as science learning motivation questionnaires and cognitive tests. …
Distance Learning Design: A Problem-Based Learning With Flipped Classroom Model Through Improving Student Learning Outcomes And Learning Motivation, Laswadi Laswadi, M Eval Setiawan, Yasni Efyanti, Jupeth Toriano Pentang, Sahar M. Taresh
Distance Learning Design: A Problem-Based Learning With Flipped Classroom Model Through Improving Student Learning Outcomes And Learning Motivation, Laswadi Laswadi, M Eval Setiawan, Yasni Efyanti, Jupeth Toriano Pentang, Sahar M. Taresh
Jurnal Inovasi Pendidikan IPA
The purpose of this study is to improve learning outcomes in the form of cognitive abilities and student learning motivation through the development of the learning design Problem-Based Learning within flipped classroom model. The study used quasi-experimental research with One Group Pretest-Post Test Design. In the research process, instruments are needed in the form of (1) multiple-choice tests as instructional cognitive measurements of students, and (2) observation sheets of learning motivation measurements in the form of motivational rubrics developed based on arcs rubrics. The increased motivation was analyzed based on the results of the questionnaire produced based on the ARCS …
Project-Based Learning E-Modules Based On Research Results On The Nutritional Content Of Sawi Asin (Fermented Mustard), Nisa Febriyanti, Hanum Mukti Rahayu, Anandita Eka Setiadi
Project-Based Learning E-Modules Based On Research Results On The Nutritional Content Of Sawi Asin (Fermented Mustard), Nisa Febriyanti, Hanum Mukti Rahayu, Anandita Eka Setiadi
Jurnal Inovasi Pendidikan IPA
The project-based learning model focuses on directing students to be more active in learning. The learning model will be effective if combined with e-module media. Because e-modules provide facilities for students to learn independently. One of the materials in class XII Biology that is applied in e-modules is biotechnology related to local potential, namely Sawi Asin fermentation. The study aims to develop project-based learning e-modules based on research results on the nutritional content of Sawi Asin fermentation. The research method uses Research and Development which adapts the Alessi and Trolip development model. There are three stages carried out, namely, planning …
Implementation Of Imwr (Inspiring-Modeling-Writing-Reporting) Scaffolding On Students Cognitive Learning Outcome In The Stoichiometry Topic, Indah Langitasari, Ratna Sari Siti Aisyah, Siti Elis Sya'adah
Implementation Of Imwr (Inspiring-Modeling-Writing-Reporting) Scaffolding On Students Cognitive Learning Outcome In The Stoichiometry Topic, Indah Langitasari, Ratna Sari Siti Aisyah, Siti Elis Sya'adah
Jurnal Inovasi Pendidikan IPA
Stoichiometry is one of the essential chemistry topics that is an abstract concept, involves complex calculations, and is related to other chemical concepts. It can cause not a few students to have difficulty learning it. Scaffolding is needed in the learning process of stoichiometry concepts to help students understand concepts more easily and improve learning outcomes. This research aims to determine differences in students' cognitive learning outcomes on the stoichiometry topic after implementing the IMWR scaffolding model. This research used experimental research with the one-group pretest-postest design. Respondents were 32 high school students who were determined by purposive sampling. The …
The Exploration Of Biochemistry Laboratory Activity: Study On Higher Education In Mataram, Yunita Arian Sani Anwar, Muti’Ah Muti'ah
The Exploration Of Biochemistry Laboratory Activity: Study On Higher Education In Mataram, Yunita Arian Sani Anwar, Muti’Ah Muti'ah
Jurnal Inovasi Pendidikan IPA
As the core of science learning, laboratory work is inseparable from learning chemistry, including biochemistry. However, the implementation of laboratory work needs reconstruction, especially in higher education, so an initial study is needed to understand the problems in laboratory work at universities. This article was a study of the working conditions of the biochemistry laboratory at the University of Mataram. This study included quantitative research with students (N = 250), lab work assistants (N = 36), laboratorium staff (N = 4), and biochemistry lecturers (N = 4) as respondents. Techniques for obtaining data through participatory observation and questionnaires. Supporting data …
Science Process Skills Of Prospective Science Teachers' In Practicum Activity At The Laboratory, Brian Ricard Wola, Jovialine Albertine Rungkat, Gerry Michael Donad Harindah
Science Process Skills Of Prospective Science Teachers' In Practicum Activity At The Laboratory, Brian Ricard Wola, Jovialine Albertine Rungkat, Gerry Michael Donad Harindah
Jurnal Inovasi Pendidikan IPA
This research aims to determine the prospective science teachers' mastery level of science process skills (SPS), the mastery level of SPS indicators, and the prospective science teachers' mastery level of SPS based on gender. This study used a descriptive method with a quantitative approach. Purposive sampling techniques are used and obtain 23 prospective science teachers during the last two years at the Universitas Negeri Manado. The research instrument used interview guidelines and observation sheets. The results showed (1) the prospective science teachers' mastery level of SPS in practicum activity at the laboratory is 80% categorized as sufficient; (2) the mastery …
Develeopment E-Modules Based Android In Newton's Law Topic For Senior High School, Ira Lelita Eriyanti, Jumadi Jumadi, Yanarti Yanarti, Wiwin Rosiningtias
Develeopment E-Modules Based Android In Newton's Law Topic For Senior High School, Ira Lelita Eriyanti, Jumadi Jumadi, Yanarti Yanarti, Wiwin Rosiningtias
Jurnal Inovasi Pendidikan IPA
Developing android-based teaching materials is an initial step to follow the presence of the society 5.0 era in the learning system. This study aimed to know the feasibility and practicality of an Android-based e-module developed on Newton's law material. This study is research and development using the 4D model from Thiagarajan with four stages of development: define, design, develop, and dissemination. The research instrument used is an expert validation sheet, students' reliability questionnaire, interview guide sheet, and e-module prototype with research subjects consisting of 50 students. The research instruments used are expert validation sheets, student reliability questionnaires, interview guide sheets, …
Quizizz As An Evaluation Of Advanced Natural Science Learning To Increase Concentration In Post-Pandemic Learning, Anita Ekantini, Ika Damayanti
Quizizz As An Evaluation Of Advanced Natural Science Learning To Increase Concentration In Post-Pandemic Learning, Anita Ekantini, Ika Damayanti
Jurnal Inovasi Pendidikan IPA
Switching online learning to learning face-to-face (FTF) post-Covid-19 pandemic in the Advanced Natural Science learning course needs good adaptation from the lecturer and student. Students are not yet fully ready to follow learning FTF. When they follow learning, students are not yet entirely focused on learning. This show that the learning concentration of students is low. This research was conducted to evaluate Advanced Natural Science learning post-Covid-19 pandemic. This study aims to determine whether giving quizzes with the application Quiziz affects students' learning concentration. This study uses a quantitative approach with a quasi-experimental method of research. This research design used …
Utilizing Social Media In Socioscientific Issues Discussion To Improve Argumentative Skills And Microbial Literacy, Yanti Herlanti, Nuryani Rustaman, Any Fitriani, Ijang Rohman
Utilizing Social Media In Socioscientific Issues Discussion To Improve Argumentative Skills And Microbial Literacy, Yanti Herlanti, Nuryani Rustaman, Any Fitriani, Ijang Rohman
Jurnal Inovasi Pendidikan IPA
Microbial literacy plays an essential role in understanding microbiology issues. Discussion of socioscientific issues is one way to improve microbial literacy and argumentative skills. Socioscientific issues discussion takes a long time if applied in an inadequate classroom. Thus, social media is used as a tool to discuss socioscientific issues. This study aims to utilize social media Facebook' in discussing socioscientific issues. The research method used is quasi-experimental. The pre-post one group design was used to know the effect of socioscientific discussion on argumentation skills, and the pre and post-control group design was used to know the differences in microbiological literacy …
Stem-Pbl Integrative Electronic Module: Is That Effective In Improving Students' Critical Thinking Skills?, Intan Phandini, Fuad Jaya Miharja, Husamah Husamah, Ahmad Fauzi, Mohammad Mirza Nuryady
Stem-Pbl Integrative Electronic Module: Is That Effective In Improving Students' Critical Thinking Skills?, Intan Phandini, Fuad Jaya Miharja, Husamah Husamah, Ahmad Fauzi, Mohammad Mirza Nuryady
Jurnal Inovasi Pendidikan IPA
The aim of this research is to develop an electronic module that integrates STEM and PBL projects to improve students' critical thinking skills. Development research conducted using the ADDIE model. The research was conducted at Muhammadiyah 2 Junior High School (JHS) of Batu. Product trials were carried out involving 25 class VII students. The data collection instrument was carried out using a questionnaire given to media experts, material experts, teachers and students to test the feasibility and practicality of the media, as well as the pretest-posttest to measure students' critical thinking skills. The results of the study show four things: …
Review Of Bénédicte Boisseron's Afro-Dog: Blackness And The Animal Question, Thomas Aiello
Review Of Bénédicte Boisseron's Afro-Dog: Blackness And The Animal Question, Thomas Aiello
Between the Species
This review evaluates Bénédicte Boisseron's Afro-Dog: Blackness and the Animal Question. In the process, it tracks the development of the academic relation between Blackness and animality.
Skin Lipids Alone Enable Conspecific Tracking In An Invasive Reptile, The Argentine Black And White Tegu Lizard (Salvator Merianae), M. Rockwell Parker, Eric A. Tillman, Lauren A. Nazarian, Megan L. Barlowe, Julianna M. Lincoln, Bryan M. Kluever
Skin Lipids Alone Enable Conspecific Tracking In An Invasive Reptile, The Argentine Black And White Tegu Lizard (Salvator Merianae), M. Rockwell Parker, Eric A. Tillman, Lauren A. Nazarian, Megan L. Barlowe, Julianna M. Lincoln, Bryan M. Kluever
United States Department of Agriculture Wildlife Services: Staff Publications
Locating potential mates in non-native habitats is one of the most important challenges faced by invasive vertebrate species. The Argentine black and white tegu lizard (Salvator merianae) is a major invasive reptile species in the contiguous United States and is rapidly expanding its range across Florida and the Southeast, in part due to inadequate management strategies and tools. Because a wide array of reptiles, especially squamates (snakes and lizards), have been well-studied for their reliance on chemical cues to locate conspecifics, our project aimed to isolate chemical cues from tegus and assess the ability of adult males and …
Hla-Dqb1*06 And Select Neighboring Hla Variants Predict Chlamydia Reinfection Risk, Kanupriya Gupta, Howard W. Wiener, Hemant K. Tiwari, William M. Geisler
Hla-Dqb1*06 And Select Neighboring Hla Variants Predict Chlamydia Reinfection Risk, Kanupriya Gupta, Howard W. Wiener, Hemant K. Tiwari, William M. Geisler
APC Fund
Associations of HLA class II alleles with genital chlamydial infection outcomes have been reported, especially HLA DQB1*06. However, the potential role of DQB1*06 in influencing reinfection risk has still not been established. The purpose of this study was to determine whether the association of DQB1*06 with chlamydia reinfection was impacted by any other nearby HLA class II variants that were also associated with reinfection. We used next-generation sequencing to map HLA class II variants spanning the HLA-DQ and -DR loci. DQB1*06 as well as DQB1*04 were confirmed as significant predictors of chlamydia reinfection, when controlling for age and percent African …
Contaminant Metals And Cardiovascular Health, Karl Kristian Lundin, Yusuf Kamran Qadeer, Zhen Wang, Salim S. Virani, Roman Leischik, Carl J. Lavie, Markus Strauss, Chayakrit Krittanawong
Contaminant Metals And Cardiovascular Health, Karl Kristian Lundin, Yusuf Kamran Qadeer, Zhen Wang, Salim S. Virani, Roman Leischik, Carl J. Lavie, Markus Strauss, Chayakrit Krittanawong
Office of the Provost
A growing body of research has begun to link exposure to environmental contaminants, such as heavy metals, with a variety of negative health outcomes. In this paper, we sought to review the current research describing the impact of certain common contaminant metals on cardiovascular (CV) health. We reviewed ten metals: lead, barium, nickel, chromium, cadmium, arsenic, mercury, selenium, zinc, and copper. After a literature review, we briefly summarized the routes of environmental exposure, pathophysiological mechanisms, CV health impacts, and exposure prevention and/or mitigation strategies for each metal. The resulting article discloses a broad spectrum of pathological significance, from relatively benign …
Early Antibody Treatment, Inflammation, And Risk Of Post-Covid Conditions, Kelly A. Gebo, Sonya L. Heath, Yuriko Fukuta, Xianming Zhu, Sheriza Baksh, Allison G. Abraham, Feben Habtehyimer, David Shade, Jessica Ruff, Malathi Ram, Oliver Laeyendecker, Reinaldo E. Fernandez, Eshan U. Patel, Owen R. Baker, Shmuel Shoham, Edward R. Cachay, Judith S. Currier, Jonathan M. Gerber, Barry Meisenberg, Donald N. Forthal, Laura L. Hammitt, Moises A. Huaman, Adam Levine, Giselle S. Mosnaim, Bela Patel, James H. Paxton, Jay S. Raval, Catherine G. Sutcliffe, Shweta Anjan, Thomas Gniadek, Seble Kassaye, Janis E. Blair, Karen Lane, Nichol A. Mcbee, Amy L. Gawad, Piyali Das, Sabra L. Klein, Andrew Pekosz, Evan M. Bloch, Daniel Hanley, Arturo Casadevall, Aaron A R Tobian, David J. Sullivan
Early Antibody Treatment, Inflammation, And Risk Of Post-Covid Conditions, Kelly A. Gebo, Sonya L. Heath, Yuriko Fukuta, Xianming Zhu, Sheriza Baksh, Allison G. Abraham, Feben Habtehyimer, David Shade, Jessica Ruff, Malathi Ram, Oliver Laeyendecker, Reinaldo E. Fernandez, Eshan U. Patel, Owen R. Baker, Shmuel Shoham, Edward R. Cachay, Judith S. Currier, Jonathan M. Gerber, Barry Meisenberg, Donald N. Forthal, Laura L. Hammitt, Moises A. Huaman, Adam Levine, Giselle S. Mosnaim, Bela Patel, James H. Paxton, Jay S. Raval, Catherine G. Sutcliffe, Shweta Anjan, Thomas Gniadek, Seble Kassaye, Janis E. Blair, Karen Lane, Nichol A. Mcbee, Amy L. Gawad, Piyali Das, Sabra L. Klein, Andrew Pekosz, Evan M. Bloch, Daniel Hanley, Arturo Casadevall, Aaron A R Tobian, David J. Sullivan
Pathology Research and Scholarship
Approximately 20% of individuals infected with SARS-CoV-2 experienced long-term health effects, as defined PCC. However, it is unknown if there are any early biomarkers associated with PCC or whether early intervention treatments may decrease the risk of PCC. In a secondary analysis of a randomized clinical trial, this study demonstrates that among outpatients with SARS-CoV-2, increased IL-6 at time of infection is associated with increased odds of PCC. In addition, among individuals treated early, within 5 days of symptom onset, with COVID-19 convalescent plasma, there was a trend for decreased odds of PCC after adjusting for other demographic and clinical …
Homoprotocatechuate Dioxygenase Active Site: Imitating The Secondary Sphere Base Via Computational Design, Muhammed Buyuktemiz, Yavuz Dede
Homoprotocatechuate Dioxygenase Active Site: Imitating The Secondary Sphere Base Via Computational Design, Muhammed Buyuktemiz, Yavuz Dede
Turkish Journal of Chemistry
Oxidative ring cleavage reactions have attracted great interest and various studies on the catechol ring-cleaving enzyme homoprotocatechuate dioxygenase (HPCD) have been reported in the literature. The available data on how the proton transfer takes place led us to design a potential HPCD model structure. A secondary sphere effect of utmost importance, the assistance of His200, which is critical for the catechol proton to migrate to dioxygen, was cautiously included on the first coordination shell. This was done mainly by modifying the axial ligands in the first coordination shell of HPCD such that the dual basic/acidic role in the proton transfer …