Digital Commons Network^™

Evaluating An Institutional Repository: A Case Study Of Singapore Management University, Pin Pin Yeo

Research Collection Library

An institutional repository (IR) was launched in 2010 for a university in Singapore. The motivations of setting up an IR were to dissemination the research output through open access, to promote the university and researchers, and to help increase their research impact. Some quantitative and qualitative performance indicators were selected and used to measure the success of the IR. For the review and the performance indicators, the data used came from the IR at SMU, interviews with faculty members, and a study of a set of journal articles available in the IR to test a hypothesis. The results of the …

Molecular Mechanisms Of Action Of Metformin: Latest Advances And Therapeutic Implications, Hong Zhu, Zhenquan Jia, Y R. Li, Igor Danelisen

Osteopathic Medicine, Jerry M. Wallace School of

Metformin is among the most widely used antidiabetic drugs. Studies over the past few years have identified multiple novel molecular targets and pathways that metformin acts on to exert its beneficial effects in treating type 2 diabetes as well as other disorders involving dysregulated inflammation and redox homeostasis. In this mini-review, we discuss the latest cutting-edge research discoveries on novel molecular targets of metformin in glycemic control, cardiovascular protection, cancer intervention, anti-inflammation, antiaging, and weight control. Identification of these novel targets and pathways not only deepens our understanding of the molecular mechanisms by which metformin exerts diverse beneficial biological effects, …

The Honors Oracle, November 2023, Honors College

Honors Oracle

Marshall University’s Honors College newsletter.

Faculty University Service Roster - November 2023, Faculty Senate

Faculty Senate Documents

A list distributed in November 2023 by the Faculty Senate of members of the governance body and affiliated committees.

Novel Method Of The Quantification Of Turbulent Fluid Flow In Silicone Artery Phantoms Using Acoustic Analysis, Julia Wong

Master's Theses

Cardiovascular disease is the leading cause of death globally and is responsible for taking 17.9 million lives per year. Despite the use of clinical treatments and detection methods, there remains a large population of individuals that suffer from CVD whose symptoms are left undetected and untreated prior to a life-threatening cardiac event. This highlights a need for an early detection method that can prevent the manifestation and worsening of the disease as well as address limitations of current early detection methods. An area of interest for early detection of CVD is subclinical atherosclerosis, which is the long, early, asymptomatic stage …

Impulsive Nonlocal Neutral Integro-Differential Equations Controllability Results On Time Scales, Suliman Alsaeed

Applied Mathematics & Information Sciences

In this work, we studied the controllability results for neutral differential time-varying equation with impulses on time scales & extend these results into nonlocal controllability of neutral functional integro-differential time-varying equation with impulses on time scales. The solutions are obtained employing standard fixed point theorems.

Impact Of Covid-19 Third Wave Omicron In India, Manmohan Singh, Garima Agarwal, K. S. Nisar, Osama Moaaz, Hegagi M. Ali

Applied Mathematics & Information Sciences

The new Covid-19 variant omicron remains a cause of concern as India is seeing a sudden spike in the number of cases related to the highly transmissible coronavirus variant that has fuelled record outbreaks in various countries in the world.Day by day the cases increases reported by union Ministry of Health and family Welfare at the end of 2021. In this study we came to a approach that omicron variant is not severe and less harmful effect in comparison of second wave in India and there is no need for more hospitalization and lockdown for this with the fact knowing …

We Are ... Marshall, November 1, 2023, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Plm-Arg: Antibiotic Resistance Gene Identification Using A Pretrained Protein Language Model, Jun Wu, Jian Ouyang, Haipeng Qin, Jiajia Zhou

Faculty Journal Articles

No abstract provided.

Growth Performance, Feed Utilization, Hematological Parameters, And Histological Features Of Nile Tilapia (Oreochromis Niloticus) Fed Diets With Supplementary Herbal Extracts Under Prolonged Water Exchange, Mohamed F.A. Abdel-Aziz, Mohammed F. El Basuini, Islam I. Teiba, Mohamed M.M. Metwally

Faculty Journal Articles

No abstract provided.

Center For Grassland Studies, November 2023

Center for Grassland Studies: Newsletters

Contents

Experiential Learning for Grassland Conservation by David Wedin

Center for Grassland Studies Policy Advisory Committee

Director’s Column by David Wedin

New Woody Invasions Ecologist Brings Additional Capacity for Grassland Conservation by Dillon Fogarty

Twidwell Racks-up awards for his work in Grassland Conservation by Geitner Simmons

Platte Basin Timelapse premieres New Film on Nine-Mile Prairie by David Wedin

CRAWL: Update on the Network for Integrated Agricultural Resilience Research by Craig Allen

CGS Outreach by Jerry Volesky

Center for Grassland Studies Awards 19 Scholarships Totaling $17,500 for 2023-2024 by David Wedin

Award winners:

Joseph O. Young Fund = Makenna Anderson, Makennen …

Spartan Daily, November 1, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 161, Issue 31

Faculty At Work, Mercedes Rose

Linfield Magazine

The Science of Social Connections: Professor Yanna Weisberg unlocks the mysteries of personality

Development Of An Angiogenic Tissue-On-A-Chip Microenvironment, Eric Stuehr

Master's Theses

Preclinical testing is necessary to investigate the safety and efficacy of novel therapeutics before moving to clinical trials, yet approximately 90% of these therapies fail once tested in humans. This has led to increased interest in developing robust preclinical models that accurately mimic the complex human in vivo physiology. Microfluidic devices that can introduce dynamic conditions to 3D cell/organoid cultures, also known as tissue-on-a-chip, have emerged as physiologically relevant in vitro preclinical models that can achieve high throughput screening of therapeutics. The research presented here aimed to develop an angiogenic environment within a novel microfluidic device to stimulate formation of …

Effects Of Recreation In The Niobrara National Scenic River On Aquatic Macroinvertebrates, Jennifer Dailey

Biology Theses, Dissertations, and Student Creative Activity

The Niobrara River is a 914 km tributary of the Missouri River. The Niobrara has a 122 km section near Valentine, Nebraska, USA that was designated a National Scenic River in 1991. Despite its protected status, this section of the river still has many human influences including livestock grazing, row-crop agriculture, upriver impoundments, and, most directly, recreational activities like kayaking, canoeing, and tubing. The goal of my thesis was to document macroinvertebrate communities within the Niobrara National Scenic River and evaluate how community assemblages and diversity responded to recreational activities. I also used macroinvertebrate assemblages as indicators for the water …

Uni Impact: Faculty/Staff Scholarly Publications And Featured Awards Newsletter, V1i3-4, 2022, Rod Library. Research & Sponsored Programs. Uni Foundation. University Of Northern Iowa.

UNI Impact: Faculty/Staff Scholarly Publications and Featured Awards Newsletter

Highlights the scholarship, research, and other scholarly work produced by University of Northern Iowa faculty, students, and staff.

This issue covers the period of April - December 2022.

Men's Basketball Media Guide 2023-2024, Wofford College. Departmet Of Athletics

Media Guides

No abstract provided.

Women's Basketball Media Guide 2023-2024, Wofford College. Departmet Of Athletics

Media Guides

No abstract provided.

Interspecies Relations In The Midst Of The Russia–Ukraine War, Tanya Richardson

Anthropology Faculty Publications

No abstract provided.

Once On This Island

Theatre and Performance Studies Programs

This Tony Award-winning musical is the sweeping, universal tale of Ti Moune, a fearless peasant girl in search of her place in the world, and ready to risk it all for love. Guided by the mighty island gods, Ti Moune sets out on a remarkable journey to reunite with the man who has captured her heart. With a score that bursts with life through its Caribbean rhythms and instruments, Once on This Island: The Musical is a timeless testament to theatre’s unlimited possibilities and that a beautiful story simply told has the power to inspire and heal all. Read more …

Protecting Wa Crops Issue 35 - November 2023, Department Of Primary Industries And Regional Development, Western Australia

Protecting WA Crops

Protecting WA Crops Issue 35 - November 2023 contents:

• Modelling to increase understanding of Ascochyta blight aggressiveness in chickpea crops
• Meet Crop Protection team member – Dr Rodrigo Pires

Stop-Ad Portal: Selecting The Optimal Pharmaceutical For Preclinical Drug Testing In Alzheimer's Disease., Sara K Quinney, Kandasamy Murugesh, Adrian Oblak, Kristen D. Onos, Michael Sasner, Anna K Greenwood, Kara H Woo, Stacey J Sukoff Rizzo, Paul R Territo

Faculty Research 2023

We propose an unbiased methodology to rank compounds for advancement into comprehensive preclinical testing for Alzheimer's disease (AD). Translation of compounds to the clinic in AD has been hampered by poor predictive validity of models, compounds with limited pharmaceutical properties, and studies that lack rigor. To overcome this, MODEL-AD's Preclinical Testing Core developed a standardized pipeline for assessing efficacy in AD mouse models. We hypothesize that rank-ordering compounds based upon pharmacokinetic, efficacy, and toxicity properties in preclinical models will enhance successful translation to the clinic. Previously compound selection was based solely on physiochemical properties, with arbitrary cutoff limits, making ranking …

A Phase Ii Study Of Bevacizumab And Temsirolimus In Advanced Extra-Pancreatic Neuroendocrine Tumors., Sonia M Abuzakhm, Vineeth Sukrithan, Briant Fruth, Rui Qin, Jonathan Strosberg, Timothy J Hobday, Thomas Semrad, Diane Reidy-Lagunes, Hedy Lee Kindler, George P Kim, Jennifer J Knox, Andreas Kaubisch, Miguel Villalona-Calero, Helen Chen, Charles Erlichman, Manisha H Shah

Oncology Articles

We assessed the efficacy and safety of combining bevacizumab with temsirolimus in patients with advanced extra-pancreatic neuroendocrine tumors. This NCI-sponsored multicenter, open-label, phase II study (NCT01010126) enrolled patients with advanced, recurrent, or metastatic extra-pancreatic neuroendocrine tumors. All patients were treated with temsirolimus and bevacizumab until disease progression or unacceptable toxicity. Temsirolimus 25 mg was administered i.v. on days 1, 8, 15, and 22 and bevacizumab 10 mg/kg i.v. on days 1 and 15 of a 4-week cycle. Discontinuation of temsirolimus or bevacizumab did not require discontinuation of the other agent. The primary endpoints were objective response rate and 6-month progression-free …

Fisheries Science Update - Pilbara Demersal Scalefish Resource - November 2023, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Science Updates

Key points: 2023 stock assessment outcomes:

• The Pilbara Demersal Scalefish Resource (PDSR) spans from the North West Cape to 120ºE and comprises over 60 demersal scalefish species, including indicator species red emperor, rankin cod, and bluespotted emperor.
• The PDSR is accessed by recreational fishers, charter operators and three commercial fisheries: Pilbara Fish Trawl (Interim) Managed Fishery, Pilbara Trap Managed Fishery, and the Pilbara Line Fishery.
• The PDSR is a key ‘food bowl’ for Western Australia, supplying the local market with about 2,500 tonnes of demersal scalefish annually.
• The PDSR provides unique and valuable recreational fishing opportunities at locations such as …

Quantitative, Photocurrent Multidimensional Coherent Spectroscopy, Adam Halaoui

Electronic Theses and Dissertations

Multidimensional coherent spectroscopy (MDCS) is a quickly growing field that has a lot of advantages over more conventional forms of spectroscopy. These advantages all come from the fact that MDCS allows us to get time resolved correlated emission and absorption spectra using very precisely chosen interactions between the density matrix and the excitation laser. MDCS spectra gives the researcher a lot of information that can be extracted purely through qualitative analysis. This is possible because state couplings are entirely separated on the spectra, and once we know how to read the data, we can see how carriers transport in the …

Chromosome-Level Genome Assembly For The Angiosperm Silene Conica., Peter D Fields, Melody M Weber, Gus Waneka, Amanda K Broz, Daniel B Sloan

Faculty Research 2023

The angiosperm genus Silene has been the subject of extensive study in the field of ecology and evolution, but the availability of high-quality reference genome sequences has been limited for this group. Here, we report a chromosome-level assembly for the genome of Silene conica based on Pacific Bioscience HiFi, Hi-C, and Bionano technologies. The assembly produced 10 scaffolds (1 per chromosome) with a total length of 862 Mb and only ∼1% gap content. These results confirm previous observations that S. conica and its relatives have a reduced base chromosome number relative to the genus's ancestral state of 12. Silene conica …

Libertarianism And The Common Law, Allen Mendenhall

Belmont Law Review

What are the qualities and characteristics of the common law that feature or reflect libertarianism? The common law is both a historical phenomenon and an active process or a juridical mode of settling disputes. Therefore, a precise answer to questions about the compatibility between libertarianism and the common law is difficult to articulate. This Essay describes elements of the common law - both its manifestation in history and its theoretical approaches to judging - that illuminate its libertarian attributes and tendencies. It suggests that the common law has epistemological importance as a kind of bottom-up ordering based on traceable patterns …

Identification Of Significant Gene Expression Changes Incorporating Heterogeneity In Perturbation Experiments, Katharine Cross

Honors Projects in Biological and Biomedical Sciences

Machine learning methods have been widely applied to the field of genomics and bioinformatics. Specifically utilizing novel machine learning algorithms to study gene-drug interactions has the potential to make a major positive impact on new drug discovery. It is possible that heterogeneity may exist within Vorinostat drug perturbation experiments due to the effects of the perturbations on the gene expressions. Thus, the challenge is to identify the most important genes in a high-dimensional setting while first identifying subpopulations to address population heterogeneity. In this work, clustering techniques are applied to first identify group sub-population structures in the gene expression changes …

Pharmacy Matters - November 2023, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "School of Pharmacy Celebrates Gratitude Month," "Pharmacy Students Join in UM Effort to Combat Opioid Overdose," "Pharmacy Alumna Among University Distinguished Alumni Honorees," "Professor Awarded $1.2M NIH Grant," "UM Partners with PainVox to Pinpoint Origin Sites of Chronic Pain," "Pharmacy Researchers Secure STTR Grant," "Pharmaceutics Professor Wins Prestigious International Award"

College Of Graduate Programs And Honors Studies Newsletter - November 2023, College Of Graduate Programs And Honors Studies, Wright State University

College of Graduate Programs and Honors Studies Newsletter

A six page newsletter created by the College of Graduate Programs and Honors Studies at Wright State University. This newsletter includes a upcoming events, message from the dean, and more.