Digital Commons Network^™

The Ecological Consequences Of Salty Fresh Waters, Bill Hintz

Sustainability Seminar Series

Freshwater ecosystems worldwide are getting saltier. This will change the ecology and functioning of freshwater ecosystems and threatens the services fresh waters provide us as humans, such as drinking water quality. In this presentation, Dr. Hintz will explain new research that investigates the ecological consequences of freshwater salinization and how current water quality guidelines need to be reevaluated to protect freshwater ecosystems.

Perovskite Cspbbr3 Solar Cells With Novel Hole-Transporting Layer Of Metal Complexes, Liqiu Zheng, Evynn S. Jackson, Ny'kesha S. Warren, Robert Owor, Zhongrui Li

Georgia Journal of Science

For the first time, the novel application of Schiff-base copper complexes in all-inorganic perovskite CsBrBr₃ solar cells has been explored and turns out they could be utilized as effective hole-transporting materials. Schiff-base copper complexes with halogen ligands (R=Cl and Br) are synthesized with an ease approach at a low cost, both of which exhibit decent power conversion efficiency of 4.55% and 5.71%, respectively, when being constructed into solar devices as hole transport layers. Thanks to high thermal/chemical stability of those Schiff-base metal complexes, the strengthened stability was achieved which is comparable to that of carbon-based CsBrBr₃ solar cells. …

Association Of Human Leukocyte Antigen (Hla) Alleles With Atopic Dermatitis In The Uae Population, Suhib Ziad Abu Jwayed

Thesis/ Dissertation Defenses

In the face of the increasing global prevalence of Atopic Dermatitis (AD), a chronic inflammatory skin condition, this thesis seeks to elucidate the genetic underpinnings of AD within the UAE population. Previous literature has underscored the ethnic-specific involvement of HLA genetic variations, especially within HLA-A and HLA-DRB1 genes, in the pathogenesis of various skin diseases, including AD. Leveraging this knowledge, our research specifically aimed to investigate the association between these HLA variants and AD in the UAE. Utilizing a comparative approach, the frequencies of HLA-A and HLA-DRB1 variants were assessed in AD patients vis-à-vis a control group. Our data, based …

Ecosystem Service Valuation Of Blue Carbon Habitats: A Review For Saltmarshes And Seagrasses, Geraldine Doolan, Stephen Hynes

Journal of Ocean and Coastal Economics

Oceans and coastal marine ecosystems, particularly vegetated coastal habitats such as mangroves, seagrass, and saltmarsh, play a significant role in the global carbon cycle as long-term carbon sinks. Ensuring that these habitats continue to function as sinks and do not become sources of emissions through habitat degradation is vital for climate and environmental policy goals. These blue carbon ecosystems also provide a number of other important ecosystem services to societies. Understanding the economic value of blue carbon ecosystems is necessary to make informed policy decisions that weigh the costs and benefits of ecosystem management plans. This paper reviews the current …

Nutritional And Health Benefits Of Singhara – A Review Article., Soma Basu, A.J. Hemamalini

International Journal of Health and Allied Sciences

Trapa Natans commonly known as Singhara or Paniphal in India. It grows throughout the East of India. Dried water chestnuts can be ground into flour to make a kind of porridge. Young nuts can be eaten raw with its greenish skin removed. The Singhara shell and core are rich in starch, dietary fiber, essential amino acids, certain types of phenols and minerals and have demonstrated various biological activities, including anticancer and antioxidant properties. Singhara contains several antioxidants that can reduce the risk of multiple chronic diseases and conditions.

The Therapeutic Potential Of Nelumbo Nucifera: A Comprehensive Review Of Its Phytochemistry And Medicinal Properties, Sparsh Bhat, Suresh Joghee, Meenakshi S. Iyer

International Journal of Health and Allied Sciences

Nelumbo nucifera generally known as ‘sacred lotus’ is a plant with high medicinal value in traditional medicine system especially in Chinese medicine system which is having a wide distribution worldwide in Asian, Western European, American and Australian continent. All the parts of the plant have different medicinal value, as their extract contains various valuable chemical constituents which yield desired remedial effects against many diseases. The plant is used traditionally more compared to its commercial usage. It has also been used for dental and skin care products in many herbal formulations. In this review, data about its general description, its distribution, …

“Cost-Effective Markers To Identify Metabolically Healthy/Unhealthy Individuals And Their Future Risk For Cardiovascular Disorders”, Shobha C Ramachandra, Akila Prashant, Akshitha Shivanna, Ananth Koushik Bhujanga, Syeda Meherunnisa, Prashant Vishwanath

International Journal of Health and Allied Sciences

Background: With the rising prevalence of metabolically healthy obese, it becomes essential to identify markers to differentiate them from metabolically unhealthy obese and their future risk for cardiovascular disorders (CVD). The study aims to identify suitable markers for risk stratification of metabolically healthy/unhealthy individuals and their risk for CVD. Method: Total 84 individuals aged 18-60 years of age without any comorbidities were enrolled. Their demographic details along with anthropometric measurements were noted. The biochemical parameters like fasting glucose, insulin, lipid profile, and serum adipokines were estimated. Insulin resistance (IR) markers and atherogenic indices were calculated. The data were analyzed on …

Effect Of Selective Serotonin Reuptake Inhibitors On Blood Glucose In Euglycemic And Streptozotocin-Induced Diabetic Albino Wistar Rats, Nagma Firdose, Ranjith Raj, Bhavya Somaplara Gangadharappa, Suresha R N, Gubbi Vani Ishika, Ramith Ramu

International Journal of Health and Allied Sciences

Background: Diabetes mellitus is one of the serious health concerns around the globe, characterized by hyperglycemia. It is also linked with several other disorders including neuropathy. One of the most typical diabetes-related comorbidities is depression. Objectives: In this investigation, euglycemic albino rats and streptozotocin-induced diabetic albino Wistar rats were used to assess the effects of fluoxetine, escitalopram, and fluvoxamine on blood glucose levels. Method: To measure euglycemic index, the three medications were given to several groups. After administering glucose, the blood glucose level was checked at 0, 60, and 150 minutes. Additionally, starting on the third day following the induction …

Descriptive And Multiple Linear Regression Analysis Of Water Quality Parameters Of Vidyaranyapuram Treatment Plant: A Case Study, Snehalatha Basavaraju, Sushma Pradeep, Sahana K S, Stavelin Abhinandithe, Jamuna Bai Aswathanarayan

International Journal of Health and Allied Sciences

The fundamental need of human beings is safe water, but urban development is generating more polluted water creating the scarcity for drinkable water. Wastewater plants are used reduce the pollutants to less than maximum permissible limits to prevent the threat to the environment and human health. Henceforth, maintaining the waste water plant’s water quality standards before permitting into the water cycle. Subsequently, statistical prediction and evaluation are critical for determining the performance and improvement of wastewater treatment plants. The impact of multiple intrinsic and extrinsic factors on the characteristics of the Vidyaranyapuram Wastewater Treatment Plant (WWTP) in Mysuru was investigated …

Shell Pnw, Victoria B. Martinez Bruno, Amy C. Hirons Dr.

Hirons Field Techniques

No abstract provided.

Ritualized Affective Performances: Syriac Etiquette Guides And Systems Intelligence In Early Christian-Muslim Encounters, Luis Josué Salés

Scripps Faculty Publications and Research

In 2009, Michael Penn published a transcription and English translation of two Syriac texts, To the Rulers of the World (ܠܘܬ ܪ''ܝܫܢܐ ܕܥܠܡܐ) and Concerning the Entrance before a New Emir (ܕܡܥܠܬܐ ܨܝܕ ܐܡܝܪܐ ܚܕܬܐ). This essay proposes a new historiographical approach to these texts based on the concepts and theoretical apparatus of systems intelligence theory and affect theory. I show how these texts use key Islamic theological and cultural ideas that would affectively resonate with the Muslim authorities while remaining non-objectionable to the orthodoxy of the Assyrian Church of the East. Specifically, I argue that Christians sometimes sought to …

Impacts Of Hydrophobic Mismatch On Antimicrobial Peptide Efficacy And Bilayer Permeabilization., Steven Meier, Zachary M Ridgway, Angela L Picciano, Gregory A. Caputo

College of Science & Mathematics Departmental Research

Antimicrobial resistance continues to be a major threat to world health, with the continued emergence of resistant bacterial strains. Antimicrobial peptides have emerged as an attractive option for the development of novel antimicrobial compounds in part due to their ubiquity in nature and the general lack of resistance development to this class of molecules. In this work, we analyzed the antimicrobial peptide C18G and several truncated forms for efficacy and the underlying mechanistic effects of the sequence truncation. The peptides were screened for antimicrobial efficacy against several standard laboratory strains, and further analyzed using fluorescence spectroscopy to evaluate binding to …

Compound Flooding In A Non-Stationary World: A Primer For Practice, Gerarda M. Shields, J. Rolf Olsen, Miguel Medina Jr., Jayantha Obeysekera, Poulomi Ganguli, Carlo Demichele, Gianfausto Salvadori, Mohammad Reza Najafi, Hamed Moftakhari, Ferdinand Diermanse, Amir Aghakouchak

Publications and Research

Compound flooding conditions present a significant challenge for civil engineers in their pursuit to design for and maintain the integrity of a structure’s entire life cycle. Coupled with non-stationary processes due to a changing climate and land use change, risk is a moving target. Through the support of ASCE’s Task Committee on Compound Flooding, the Hydroclimatology Engineering Adaptation (HYDEA) sub-committee is developing a Manual of Practice (MOP) to provide a synthesis of available tools and methods of best practice for civil engineers designing for compound flooding conditions. This paper presents a primer for practicing civil engineers on this work. Hydrodynamic …

The Relationship Between Spirituality, Religiosity, Attachment, And Substance Use/Substance Involvement Among Adult Attendees Of Houses Of Worship, Jessica Jeanette Hames

Walden Dissertations and Doctoral Studies

No abstract provided.

Pcbp1 Regulates Lifr Through Fam3c To Maintain Breast Cancer Stem Cell Self-Renewal And Invasiveness, William S. Streitfeld

MUSC Theses and Dissertations

The poly(rC) binding protein 1 gene (PCBP1) encodes the heterogenous nuclear ribonucleoprotein E1 (hnRNPE1), a nucleic acid-binding protein that plays a tumor-suppressive role in mammary epithelial cells by regulating phenotypic plasticity and cell fate. Following the loss of PCBP1 function, the FAM3C gene (encoding the Interleukin-like EMT inducer, or “ILEI” protein) and the leukemia inhibitory factor receptor (LIFR) gene are upregulated. Interaction between FAM3C and LIFR in the extracellular space induces phosphorylation of signal transducer and activator of transcription 3 (pSTAT3). Overexpression and/or hyperactivity of STAT3 has been detected in 40% of breast cancer cases and is associated with a …

Binding Interactions Of Biologically Relevant Molecules Studied Using Surface-Modified And Nanostructured Surfaces, Palak Sondhi

Dissertations

This research focuses on the field of surface nanobioscience, wherein different nanosurfaces that will be used as working electrodes in the electrochemical cell are manufactured and surface modified to understand the critical binding interactions between biologically significant molecules like proteins, carbohydrates, small drug molecules, and glycoproteins. This research is essential if we are to determine whether a synthetic molecule can serve as a therapeutic candidate or diagnose a disease in its early stages. In order to fully understand the binding interactions, the study begins with defining some of the fundamental concepts, principles, and analytical tools for biosensing.

Afterwards, we addressed …

Blue Runner (Caranx Crysos) Neurocranium, Delaney Deinlein, Gabriel Droz, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from approximately 30 cm total length (TL) Blue Runner (Caranx crysos), collected from Dania Pier in 2023 by Charles Klinger.

Mimicking Biofilms: Photosynthetic Assessments Of C. Reinhardtii In 3 Physical Forms, John Michael Roesgen

Biology ETDs

Oxygenic photosynthesis supports the majority of life on Earth through the capture of energy from sunlight and the assimilation of CO₂ into basic building blocks of cells. Microalgae are fast growing and account for about half of global photosynthesis. In addition, they can be cultivated and their metabolism can be redirected to generate additional useful products ranging from biofuels to pharmaceuticals. However, the efficiency of metabolite production is severely impacted by the slow diffusion of CO₂ through water and the high energetic costs of harvesting microalgae from liquid cultures. Microalgae grow in open water, but they also form …

Oregon State Rank Assesment For Johnson's Hairstreak (Callophrys Johnsoni), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Johnson's hairstreak (Callophrys johnsoni) using NatureServe methodology, 2023.

Circulating Tumor Dna Monitoring On Chemo-Immunotherapy For Risk Stratification In Advanced Non-Small Cell Lung Cancer, Bruna Pellini, Russell W Madison, Merrida A Childress, Shoshana T Miller, Ole Gjoerup, Jason Cheng, Richard S P Huang, Michael Krainock, Pratyush Gupta, Wei Zou, David S Shames, Solomon Moshkevich, Marcus Ballinger, Minetta C Liu, Amanda Young, Minu K Srivastava, Geoffrey R Oxnard, Mark A Socinski

Faculty, Staff and Student Publications

PURPOSE: Chemoimmunotherapy (chemoIO) is a prevalent first-line treatment for advanced driver-negative non-small cell lung cancer (NSCLC), with maintenance therapy given after induction. However, there is significant clinical variability in the duration, dosing, and timing of maintenance therapy after induction chemoIO. We used circulating tumor DNA (ctDNA) monitoring to inform outcomes in patients with advanced NSCLC receiving chemoIO.

EXPERIMENTAL DESIGN: This retrospective study included 221 patients from a phase III trial of atezolizumab+carboplatin+nab-paclitaxel versus carboplatin+nab-paclitaxel in squamous NSCLC (IMpower131). ctDNA monitoring used the FoundationOne Tracker involving comprehensive genomic profiling of pretreatment tumor tissue, variant selection using an algorithm to exclude nontumor …

Dietary L-Tryptophan Consumption Determines The Number Of Colonic Regulatory T Cells And Susceptibility To Colitis Via Gpr15, Nguyen Van, Karen Zhang, Rachel Wigmore, Anne Kennedy, Carolina Dasilva, Jialing Huang, Manju Ambelil, Jose Villagomez, Gerald O'Connor, Randy Longman, Miao Cao, Adam Snook, Michael Platten, Gerard Kasenty, Luis Sigal, George C Prendergast, Sangwon Kim

Department of Microbiology and Immunology Faculty Papers

Environmental factors are the major contributor to the onset of immunological disorders such as ulcerative colitis. However, their identities remain unclear. Here, we discover that the amount of consumed L-Tryptophan (L-Trp), a ubiquitous dietary component, determines the transcription level of the colonic T cell homing receptor, GPR15, hence affecting the number of colonic FOXP3⁺ regulatory T (Treg) cells and local immune homeostasis. Ingested L-Trp is converted by host IDO1/2 enzymes, but not by gut microbiota, to compounds that induce GPR15 transcription preferentially in Treg cells via the aryl hydrocarbon receptor. Consequently, two weeks of dietary L-Trp supplementation nearly double …

Functional Aggregation Of Cell-Free Proteins Enables Fungal Ice Nucleation, Ralph Schwidetzky, Ingrid De Almeida Ribeiro, Nadine Bothen, Anna T. Backes, Arthur L. Devries, Mischa Bonn, Janine Fröhlich-Nowoisky, Valeria Molinero, Konrad Meister

Chemistry and Biochemistry Faculty Publications and Presentations

Biological ice nucleation plays a key role in the survival of cold-adapted organisms. Several species of bacteria, fungi, and insects produce ice nucleators (INs) that enable ice formation at temperatures above −10 °C. Bacteria and fungi produce particularly potent INs that can promote water crystallization above −5 °C. Bacterial INs consist of extended protein units that aggregate to achieve superior functionality. Despite decades of research, the nature and identity of fungal INs remain elusive. Here, we combine ice nucleation measurements, physicochemical characterization, numerical modeling, and nucleation theory to shed light on the size and nature of the INs from the …

Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation, Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang

USF Patents

Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.

Novel Clinical Trial Designs With Dose Optimization To Improve Long-Term Outcomes, Peter F Thall, Yong Zang, Andrew G Chapple, Ying Yuan, Ruitao Lin, David Marin, Pavlos Msaouel

Faculty, Staff and Student Publications

Conventional designs for choosing a dose for a new therapy may select doses that are unsafe or ineffective and fail to optimize progression-free survival time, overall survival time, or response/remission duration. We explain and illustrate limitations of conventional dose-finding designs and make four recommendations to address these problems. When feasible, a dose-finding design should account for long-term outcomes, include screening rules that drop unsafe or ineffective doses, enroll an adequate sample size, and randomize patients among doses. As illustrations, we review three designs that include one or more of these features. The first illustration is a trial that randomized patients …

Post-Acute Sequelae Of Covid-19 (Pasc) In Pediatrics: Factors That Impact Symptom Severity And Referral To Treatment., Catherine Soprano, Ryan Ngo, Casey A Konys, Ashley Bazier, Katherine Salamon

Department of Medicine Faculty Papers

The post-acute sequelae of COVID-19 (PASC) is a complex condition. While there are emerging studies on its effects in adults, there is scarce research regarding the long-term effects of COVID-19 infection among youth. Several researchers have likened long-haul COVID-19 to chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and postural orthostatic tachycardia syndrome (POTS). In adults, the prognosis for these diagnoses is less promising than that in youth; however, there is currently very little information available on the presentation of youth with PASC. A better understanding of the specific symptom presentation for youth diagnosed with PASC is necessary. Retrospective chart reviews were conducted …

Novak, Jean Marie, San Jose State University

Emeritus and Retired Faculty Biographies

University of California, Berkeley & SFSU, Doctoral Program - Ph.D. - 1991

• Major - Special Education Emphasis in Neuro-Speech Pathology and Psychology

California State University, Fresno, M.A. - 1980

• Major - Speech Pathology

California State University, Fresno, B.A. - 1978

• Major - Communicative Disorders

University of San Francisco, San Francisco 1974-77

• Major – Pre-Medicine: Biological Sciences
• Minor – Theology and Philosophy

Colsa Grad Student Leads 'Day As A Scientist' Event For Manchester High Schoolers, Keith Testa

UNH Today Archive

No abstract provided.

Academic Senate - Agenda, 11/14/2023, Academic Senate

Academic Senate Agendas

No abstract provided.

A Dance Of Resistance: The Puerto Rican Bomba As A Means To Challenge Intersections Of Discrimination On The Island, Daniel Loving

LSU Master's Theses

This thesis examines the Puerto Rican Bomba as a multifaceted cultural and political phenomenon, focusing on its pivotal role in challenging and subverting the enduring issues of racial and gender discrimination on the Island. Drawing from an interdisciplinary framework that encompasses cultural studies, anthropology, history, performance and film studies, this research elucidates the complex interplay between Bomba's rhythmic and choreographic elements, its historical evolution, and its contemporary significance in the context of Puerto Rico's sociopolitical landscape. By analyzing Bomba's historical roots in African and indigenous traditions, its adaptation during colonial and post-colonial eras, and its ongoing relevance in the struggle …

Copyright 2023 Giarikos Et Al. Distributed Under Creative Commons Cc-By 4.0 Open Access Assessing The Ecological Risk Of Heavy Metal Sediment Contamination From Port Everglades Florida Usa, Dimitri Giarikos, Laura White, Andre M. Daniels, Radleigh Santos, Paul Baldauf, Amy Hirons

SECLER Data

Port sediments are often contaminated with metals and organic compounds from anthropogenic sources. Remobilization of sediment during a planned expansion of Port Everglades near Fort Lauderdale, Florida (USA) has the potential to harm adjacent benthic communities, including coral reefs. Twelve sediment cores were collected from four Port Everglades sites and a control site; surface sediment was collected at two nearby coral reef sites. Sediment cores, sampled every 5 cm, were analyzed for 14 heavy metals using inductively coupled plasma-mass spectrometry. Results for all three locations yielded concentration ranges (mg/g): As, Cd, Cr, Co, Cu, Pb, Mn, Hg, Mn, Ni, Se, …