Digital Commons Network^™

Investigation Of Public Trust In Science In Connection With Views About Tentative Nature Of Science And Epistemological Beliefs, Asghar Pervaiz Gill

Dissertations

Trust in science is contested in everyday discourse and decision-making. Science education research and instruction must delve into and contribute to enhancing public trust in science. In this context, nature of science (NOS), and epistemological beliefs (EBs) emerge as closely related research areas highlighting the tentative NOS and uncertain aspects of knowledge, which can potentially influence trust in science. In a series of three interrelated studies, this research explores the public trust in science in relation to NOS views and EBs.

The first study emphasizes the role of science education in building trust among undergraduate chemistry students. It assesses the …

Measuring Multicultural Competence In Counseling, Martha Mae Golubski

Dissertations

Pedersen (1999) described multicultural counseling as the “fourth force” in psychology. The description is used to imply that multiculturalism is the next theory to understand human behavior, complementary to the other three forces: psychodynamic, behavioral, and humanistic explanations. Despite the attention being given to multiculturalism, professional organizations, training institutions, and service providers are still trying to understand what it means to have competency in multicultural counseling. Researchers have made decades of efforts to define and measure multicultural counseling competence; yet, there is still limited data about how multicultural training efforts influence these competencies and how counselor multicultural competency affects clients’ …

Oncolytic Tanapoxvirus Recombinants Expressing Mil-2, Flagellin-C, And Mccl2 Regress Human Cancer Xenografts In Immune Deficient Nude Mice And Immune Cell Reconstituted Balb/C Nude Mice., Michael Leonard Monaco

Dissertations

Tanapoxvirus (TPV) is a double stranded DNA virus from the genus Yatapoxvirus which has been engineered for the purpose of potentially treating a number of human cancers. Previous studies have shown TPV recombinants are capable of inducing tumor inhibition and even regression in athymic nude mice bearing human cancer xenografts of colorectal, melanoma and triple negative breast cancer (TNBC). However, TPV is host-restricted to humans and monkeys, including cancerous cells, which has provided a unique obstacle in its development as an oncolytic virus (OV). Namely, standard syngeneic mouse models cannot be used as test systems to evaluate TPV’s efficacy against …

Influence Of A Multicultural Counseling And Psychology Course On Counseling Psychology And Counselor Education Master’S Students Color-Blind Ideologies And Ethnic Identity, Rebecca Tuinstra

Dissertations

The primary purpose of this study was to examine whether ethnic identity awareness mediates the relationship between completion of a Multicultural Counseling and Psychology Course and color-blind ideology endorsement. The participants included 93 master’s level counseling psychology and counselor education trainees attending a predominantly White university in the Midwest region of the United States. The study used a quantitative, pre- and post-test descriptive research design. Using mediation analysis, this study estimated the influence of completing a Multicultural Counseling and Psychology Course on awareness of ethnic identity and use of color-blind ideology while controlling for social desirability among master’s level counseling …

The Effects Of Adolescent Trauma, Mental Health Treatment, And Demographic Variables On Educational Outcome, Christopher Postema

Dissertations

Poor educational performance in adolescence can occur due to trauma, substance use, or other stressors. This study used conflict theory as a foundation, suggesting differences in educational outcomes can be attributed to systems perpetuating the current power structures that cause inequality in academic opportunities and performance. Trauma in adolescence can have adverse effects on educational outcomes and emotional stability. Research suggests that mental health therapy as well as a reduction in trauma symptoms can improve educational outcomes. Race, gender, substance use, socioeconomic status, and employment are important variables that could influence educational outcomes. Interaction terms were found in the literature …

Antiracist School Counseling Pedagogy: A Quasi-Experimental Multiple Regression Analysis, Star L. Zetocha

Dissertations

America’s K-12 schools, which were initially created exclusively for White children, are racialized institutions (Spring, 2019). School counseling ethics now obligate school counselors to engage in antiracist praxis in schools, yet school counselors-in-training (SCITs) are not typically provided with explicit training in antiracism, which allows them to enter the field with colorblind racial attitudes that inhibit them from recognizing and confronting racism in schools (Gibson & Fripp, 2022). The purpose of this research was to examine the relationship between colorblind racial attitudes and antiracist behaviors of school counselors in-training who had and had not taken an antiracist school counseling course. …

The Pathway From Sensory Processing Sensitivity To Physical Health: Stress As A Mediator, Jordan Kenemore, Juliana Chavez, Grant Benham

Psychological Science Faculty Publications

Sensory processing sensitivity (SPS) has been proposed as an innate trait associated with differences in the processing and reactivity to internal and external stimuli. To date, there has been limited research on the association between SPS and physical health and only one study examining mediators of this relationship. The aim of this study was to examine psychological stress as a mediator of the SPS-health relationship in a predominately Hispanic sample of 923 adult undergraduates attending university between 2018 and 2020. We identified three SPS factors, each of which were associated with poorer physical health as assessed through two psychometrically validated …

Gaze And Avoidant Patterns Of Visual Attention To Aversive Stimuli During Fear Habituation Trial: A Pilot Eye Tracking Study, Minoru Takahashi, Manabu Kikuchi, Jun-Ichi Yamamoto, Michiyo Hirai

Psychological Science Faculty Publications

Previous studies have revealed that attentional bias toward aversive stimuli may play a causal role in the development and maintenance of anxiety disorders. This pilot study designed an experiment, using eye tracking, to capture gaze patterns individuals may display during a fear habituation trial. Three trials were conducted with twenty-eight subjects who reported aversion to insects. Pictures of cockroaches were used as aversive stimuli. The time proportion of the total visit duration and average visit duration toward aversive stimuli were analyzed using a mixed ANOVA, with three habituation trials and four self-report on fear level scores as within-participants factors. …

A Hybrid Cognitive Model For Machine Agents In Project And Action Teams, Joshua A. Lapso

Theses and Dissertations

High performing human teams transcend complex domain uncertainty by achieving an emergent state of shared cognition, in which knowledge is organized, represented, and distributed to team members for rapid execution. However, this requires that individuals emit perceivable qualities upon which other members can make inferences about intent. In pursuit of future human and machine team studies, this research presents a hybrid cognitive model for machine agents in fully cooperative and semi-cooperative action and project teams. The hybrid cognitive model unifies the characteristics of the shared mental model and transactive memory system. The resultant model facilitates anytime selection over the two …

Illinois State University, One Hundred And Sixty-Fourth Annual Commencement, December 2023, Illinois State University

Commencement Programs

Illinois State University
One Hundred and Sixty-Fourth Annual Commencement
December 2023

Shift Variant Image Deconvolution Using Deep Learning, Arnab Ghosh

Theses

Image Deconvolution is a well-studied problem that seeks to restore the original sharp image from a blurry image formed in the imaging system. The Point Spread function(PSF) of a particular system can be used to infer the original sharp image given the blurred image. However, such a problem is usually simplified by making the shift-invariant assumption over the Field of View (FOV). Realistic systems are shift-variant; the optical system’s point spread function depends on the position of the object point from the principal axis. For example, asymmetrical lenses can cause space variant aberration. In this paper, we first simulate our …

Mutation Of The Pebp-Like Domain Of The Mitoribosomal Mrpl35/Ml38 Protein Results In Production Of Nascent Chains With Impaired Capacity To Assemble Into Oxphos Complexes, Jodie M. Box, Jessica M. Anderson, Rosemary A. Stuart

Biological Sciences Faculty Research and Publications

Located in the central protuberance region of the mitoribosome and mitospecific mL38 proteins display homology to PEBP (Phosphatidylethanolamine Binding Protein) proteins, a diverse family of proteins reported to bind anionic substrates/ligands and implicated in cellular signaling and differentiation pathways. In this study, we have performed a mutational analysis of the yeast mitoribosomal protein MrpL35/mL38 and demonstrate that mutation of the PEBP-invariant ligand binding residues Asp(D)232 and Arg(R)288 impacted MrpL35/mL38’s ability to support OXPHOS-based growth of the cell. Furthermore, our data indicate these residues exist in a functionally important charged microenvironment, which also includes Asp(D)167 of MrpL35/mL38 and Arg(R)127 of the …

Algorithmic And Computational Approaches For Improving The Efficiency Of Mobile Genomic Element Discovery, A Bioinformatics Framework, Fatema Shormin

All Theses

Through this research, we are showcasing the application of computational approaches to the discoveries in the life sciences spectrum. Our current research not only focused on mobile genetic elements but also developed the computational methods that enabled these findings. We combined the biology sciences and computer science in our research, which is essentially multidisciplinary. To that end, this research intricately probed the role and implications of mobile genetic elements, emphasizing transposable elements. These dynamic components wielded substantial influence over genomic architecture's structure, function, and evolutionary adaptations. An integral component of our study is the innovative computational tool, Target/IGE Retriever (TIGER), …

Antibody Banding Patterns On The Enzyme-Linked Immunoelectrotransfer Blot (Eitb) Assay Clearly Discriminate Viable Cysticercosis In Naturally Infected Pigs, Gianfranco Arroyo, Andrés G. Lescano, Cesar M. Gavidia, Maria Teresa Lopez-Urbina, Miguel Ara-Gomez, Lucho Gomez-Puerta, Seth E. O’Neal, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Enzyme-linked immunoelectrotransfer blot (EITB) detects antibodies against seven Taenia solium larvae antigens in three protein families (GP50, T24/42, and 8-kDa) with different structures and functions. EITB banding patterns against these antigens in pigs provide information about the course of infection and may discriminate viable cysticercosis. We analyzed the banding patterns and infection outcomes (presence of viable cysts, degenerated cysts, and any cysts) of 512 rural pigs. Banding patterns were grouped into homogenous classes using latent class analysis, and relationships with infection outcomes were assessed. Four classes were identified: 1 (n = 308, EITB-negative or positive for the GP50 family), 2 …

Identifying Healthy Individuals With Alzheimer’S Disease Neuroimaging Phenotypes In The Uk Biobank, Tiago Azevedo, Richard A.I. Bethlehem, David J. Whiteside, Nol Swaddiwudhipong, James B. Rowe, Pietro Lió, Timothy Rittman, Gail Li, Eric C. Petrie, Elaine R. Peskind, Teresa Villena, Walter Martinez, Carl Sadowsky, Athena Lee, Lisa Ravdin, Michael Lin, Gloria Chiang, Norman Relkin, Robert B. Santulli, Mary L. Hynes, Marc Seltzer, Laura A. Flashman, Karen Anderson, Karen Blank, Godfrey D. Pearlson, Smita Kittur, Stephen Correia, Paul Malloy, Stephen Salloway, Steven Potkin, Paul Newhouse, Angelica Garcia, Jiong Shi, Joseph Masdeu

Clinical Research Faculty Publications

Spotting people with dementia early is challenging, but important to identify people for trials of treatment and prevention. We used brain scans of people with Alzheimer’s disease, the commonest type of dementia, and applied an artificial intelligence method to spot people with Alzheimer’s disease. We used this to find people in the Healthy UK Biobank study who might have early Alzheimer’s disease. The people we found had subtle changes in their memory and thinking to suggest they may have early disease, and we also found they had high blood pressure and smoked for longer. We have demonstrated an approach that …

Refining The Diagnosis Of Gestational Diabetes Mellitus: A Systematic Review And Meta-Analysis, Ellen C. Francis, Camille E. Powe, William L. Lowe, Sara L. White, Sara L. White, Denise M. Scholtens, Jiaxi Yang, Yeyi Zhu, Cuilin Zhang, Marie France Hivert, Marie France Hivert, Soo Heon Kwak, Arianne Sweeting, Paul W. Franks, Stephen S. Rich, Robert Wagner, Tina Vilsbøll, Kimberly K. Vesco, Miriam S. Udler, Tiinamaija Tuomi, Emily K. Sims, Jennifer L. Sherr, Robert K. Semple, Rebecca M. Reynolds, Maria J. Redondo, Leanne M. Redman, Richard E. Pratley, Rodica Pop-Busui, Toni I. Pollin, Wei Perng, Ewan R. Pearson, Susan E. Ozanne, Katharine R. Owen, Richard Oram

Clinical Research Faculty Publications

Background: Perinatal outcomes vary for women with gestational diabetes mellitus (GDM). The precise factors beyond glycemic status that may refine GDM diagnosis remain unclear. We conducted a systematic review and meta-analysis of potential precision markers for GDM. Methods: Systematic literature searches were performed in PubMed and EMBASE from inception to March 2022 for studies comparing perinatal outcomes among women with GDM. We searched for precision markers in the following categories: maternal anthropometrics, clinical/sociocultural factors, non-glycemic biochemical markers, genetics/genomics or other -omics, and fetal biometry. We conducted post-hoc meta-analyses of a subset of studies with data on the association of maternal …

Oregon State Rank Assessment For Oak Titmouse (Baeolophus Inornatus), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Oak Titmouse (Baeolophus inornatus) using NatureServe methodology, 2024.

Nanobubble Technology For The Removal Of Mib And Geosmin From Drinking Water, Meryem Soyluoglu

All Dissertations

The presence of taste and odor (T&O) compounds in drinking water has been historically a major challenge for water utilities. They are difficult to remove using conventional water treatment processes, a combination of coagulation, flocculation, sedimentation, filtration, and chlorination. However, activated carbon (AC) adsorption, advanced oxidation processes, and biofiltration can be effective. The seasonal nature of T&O events makes it difficult to justify installing dedicated treatment technologies. Additionally, incorporating these technologies into existing water treatment plants can be expensive and require significant upgrades. Therefore, water utilities are always interested in exploring new approaches to minimize the occurrence and removal of …

A History Of Complex Simple Lie Algebras, Avrila Frazier

Electronic Theses and Dissertations

In 1869, prompted by his work in differential equations, Sophus Lie wondered about categorizing what he called “closed systems of commutative transformations,” while around the same time, Wilhelm Killing’s work on non-Euclidean geometry encountered related topics. As mathematicians recognized this as a division of abstract algebra, the area became known as “continuous transformation groups," but we now refer to them as Lie groups.

Patterns and structures emerged from their work, such as describing Lie groups in connection with their associated Lie algebras, which can be categorized in many important ways. In this paper, we focus on Lie algebras over the …

The Influence Of Salinity And Vegetation Texture On The Ecological Roles Of Insects In Tidal Marshes In Louisiana, Benjamin G. Aker, Claudia Husseneder, Lane D. Foil

Faculty Publications

Tidal marsh insect communities are influenced by both salinity and aspects of vegetation texture (vegetation diversity, plant density, and architectural structure). These factors affect the abundances and intra- and interguild interactions of these insects and should result in broad-scale variation in the distribution and ecological functioning of tidal marsh insect communities along these gradients. However, this assumption has not been tested within Gulf Coast marshes, and the insect communities and their ecological roles are not well known. This study identifies how family-level insect biodiversity varies by salinity and which factors are most important in affecting the distribution of insect functional …

A Survey On Mosquito Control Knowledge And Insecticide Use In New Orleans, La, 2020–2021, Erin R. Cloherty, Janet C. Mcallister, James A. Ottea, Kristen Healy, Claudia Riegel

Faculty Publications

Mosquitoes are a known public nuisance and can vector various diseases. Historically, New Orleans, LA, has long been acquainted with the burden of mosquito-borne diseases, such as malaria and yellow fever in the 20th century and West Nile virus in the 21st century. Government mosquito control awareness campaigns have been around for decades as has the use of organophosphate and pyrethroid insecticides by mosquito abatement districts. However, few data are available on public perception of mosquito control and public usage of insecticides to kill mosquitoes in New Orleans. We conducted a survey from August 2020 to July 2021 to evaluate …

Droid: Dose-Ranging Approach To Optimizing Dose In Oncology Drug Development, Beibei Guo, Ying Yuan

Faculty Publications

In the era of targeted therapy, there has been increasing concern about the development of oncology drugs based on the “more is better” paradigm, developed decades ago for chemotherapy. Recently, the US Food and Drug Administration (FDA) initiated Project Optimus to reform the dose optimization and dose selection paradigm in oncology drug development. To accommodate this paradigm shifting, we propose a dose-ranging approach to optimizing dose (DROID) for oncology trials with targeted drugs. DROID leverages the well-established dose-ranging study framework, which has been routinely used to develop non-oncology drugs for decades, and bridges it with established oncology dose-finding designs to …

Building Resilience To Extreme Weather And Climate Events In The Rural Water And Wastewater Sectors, Nathan P. Kettle, Sarah F. Trainor, Renee Edwards, Donald Antrobus, Curt Baranowski, Tina Buxbaum, Kevin Berry, Michael Brubaker, Kristine L. De Long, Steve Fries, Davin Holen, Barry Keim, Danielle Meeker, Harry Penn, Cheryl Rosa, Rick Thoman, John Walsh, Jian Zhang

Faculty Publications

Extreme weather and climate events pose significant risks to rural water and wastewater systems. We examine the vulnerability of the water sector to weather and climate extremes in rural, predominantly Indigenous and underserved coastal areas and analyze how networks support resilience. Drawing on the analysis of 39 web-based questionnaire responses and 19 interviews with rural water and wastewater managers and service providers in southern Louisiana and western Alaska, this article reports a range of interrelated historical, environmental, and social factors that influence vulnerability to extreme weather events. Formal and informal social networks serve multiple roles in building resilience. These roles …

A Trait Dataset For Freshwater Mussels Of The United States Of America, Garrett W. Hopper, Jamie R. Bucholz, Traci P. Dubose, Kaelyn J. Fogelman, Sean M. Keogh, Megan E. Kubala, Matthew B. Lodato, David H. Nichols, Irene Sánchez González, John M. Pfeiffer, James A. Stoeckel, Jeffrey D. Lozier, Carla L. Atkinson

Faculty Publications

The United States of America has a diverse collection of freshwater mussels comprising 301 species distributed among 59 genera and two families (Margaritiferidae and Unionidae), each having a unique suite of traits. Mussels are among the most imperilled animals and are critical components of their ecosystems, and successful management, conservation and research requires a cohesive and widely accessible data source. Although trait-based analysis for mussels has increased, only a small proportion of traits reflecting mussel diversity in this region has been collated. Decentralized and non-standardized trait information impedes large-scale analysis. Assembling trait data in a synthetic dataset enables comparison across …

New Insights In The Mechanisms Of Weight-Loss Maintenance: Summary From A Pennington Symposium, Emily W. Flanagan, Redin Spann, Sarah E. Berry, Hans Rudolf Berthoud, Stephanie Broyles, Gary D. Foster, Jonathan Krakoff, Ruth J.F. Loos, Michael R. Lowe, Danielle M. Ostendorf, Tiffany M. Powell-Wiley, Leanne M. Redman, Michael Rosenbaum, Philip R. Schauer, Randy J. Seeley, Boyd A. Swinburn, Kevin Hall, Eric Ravussin

Division of Basic Science Faculty Publications

Obesity is a chronic disease that affects more than 650 million adults worldwide. Obesity not only is a significant health concern on its own, but predisposes to cardiometabolic comorbidities, including coronary heart disease, dyslipidemia, hypertension, type 2 diabetes, and some cancers. Lifestyle interventions effectively promote weight loss of 5% to 10%, and pharmacological and surgical interventions even more, with some novel approved drugs inducing up to an average of 25% weight loss. Yet, maintaining weight loss over the long-term remains extremely challenging, and subsequent weight gain is typical. The mechanisms underlying weight regain remain to be fully elucidated. The purpose …

Sensory Spinal Interoceptive Pathways And Energy Balance Regulation, Heike Münzberg, Hans Rudolf Berthoud, Winfried L. Neuhuber

Division of Basic Science Faculty Publications

Interoception plays an important role in homeostatic regulation of energy intake and metabolism. Major interoceptive pathways include gut-to-brain and adipose tissue-to brain signaling via vagal sensory nerves and hormones, such as leptin. However, signaling via spinal sensory neurons is rapidly emerging as an additional important signaling pathway. Here we provide an in-depth review of the known anatomy and functions of spinal sensory pathways and discuss potential mechanisms relevant for energy balance homeostasis in health and disease. Because sensory innervation by dorsal root ganglia (DRG) neurons goes far beyond vagally innervated viscera and includes adipose tissue, skeletal muscle, and skin, it …

Amazonian Mixed-Species Flocks Demonstrate Flexible Preferences For Vertical Forest Structure, Charles P.J. Coddington, W. Justin Cooper, Cameron L. Rutt, Karl Mokross, Bruna R. Amaral, Philip C. Stouffer, David A. Luther

Faculty Publications

How species interact with human-disturbed environments is a central focus of conservation biology. Within disturbed landscapes, regenerating forests have potential to provide habitat for forest species, especially as increasing amounts of primary forest are lost. As secondary forest regenerates beside primary forest, it increases habitat heterogeneity. However, relatively little is known about the influence of habitat heterogeneity on space use. In this study, we analyzed the topography and vertical vegetation structure of regenerating forest, small forest fragments, and undisturbed rainforest in the central Amazon to determine (1) how these structural characteristics influence understory mixed-species flock space use and (2) how …

Modeling Of Cryopreservation Pathway Operation At An Aquatic Biomedical Stock Center For Zebrafish, Sarah Bodenstein, Fidan Abdullayeva, Joy M. Murphy, Zoltan M. Varga, Terrence R. Tiersch

Faculty Publications

Aquatic biomedical model organisms play a substantial role in advancing our understanding of human health, however, comparably little work has been directed towards developing dependable, high-throughput storage programs for valuable genetic resources. The Zebrafish International Resource Center (ZIRC) has developed a standardized cryopreservation pathway and stored thousands of genetic lines in their repository for use by the biomedical research community. This has yet to be replicated in other facilities, and an overall repository-level pathway has never been analyzed for aquatic species. To encourage repository development for other biomedical models and to improve the ZIRC storage process and system, this study …

Leslie Paul Kozak, Phd (1940-2023), Eric Ravussin, Sven Enerback, Robert Koza

Clinical Research Faculty Publications

No abstract provided.

Effect Of An Acute Long-Duration Exercise Bout On Skeletal Muscle Lipid Droplet Morphology, Glut 4 Protein, And Perilipin Protein Expression, Sudip Bajpeyi, Jehu N. Apaflo, Victoria Rosas, Keisha Sepulveda-Rivera, Armando Varela-Ramirez, Jeffrey D. Covington, Jose E. Galgani, Eric Ravussin

Clinical Research Faculty Publications

Purpose: Smaller lipid droplet morphology and GLUT 4 protein expression have been associated with greater muscle oxidative capacity and glucose uptake, respectively. The main purpose of this study was to determine the effect of an acute long-duration exercise bout on skeletal muscle lipid droplet morphology, GLUT4, perilipin 3, and perilipin 5 expressions. Methods: Twenty healthy men (age 24.0 ± 1.0 years, BMI 23.6 ± 0.4 kg/m2) were recruited for the study. The participants were subjected to an acute bout of exercise on a cycle ergometer at 50% VO2max until they reached a total energy expenditure of 650 kcal. The study …