Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 94621 - 94650 of 818753

Full-Text Articles in Entire DC Network

Improving The Quality Of Micronutrient Food Composition Data In Sub-Saharan Africa Using Predictive Analytics, Junior Mbuyamba Muka Dec 2023

Improving The Quality Of Micronutrient Food Composition Data In Sub-Saharan Africa Using Predictive Analytics, Junior Mbuyamba Muka

Theses and Dissertations

High-quality food composition data are indispensable for decision making in several health, agricultural, and nutrition-related activities. Analytical data are the most accurate type of food composition data (FCD). Yet, most food composition databases (FCDBs) compiled in Sub-Saharan Africa only contain a small amount of analytical data collected from foods consumed in this region. Most of the data are either borrowed / copied from FCDBs collected in other parts of the world, calculated, imputed, or presumed data. Even with these alternative types, FCDBs in Sub-Saharan Africa have not reached a satisfactory level of completeness, as they still have missing data for …

Go to article

Apolipoprotein E Adopts An Antiparallel Dimer In Discoidal Lipoproteins, Michael Ray Strickland Dec 2023

Apolipoprotein E Adopts An Antiparallel Dimer In Discoidal Lipoproteins, Michael Ray Strickland

Arts & Sciences Graduate Student Theses and Dissertations

Apolipoprotein E (ApoE) is the major lipoprotein in the central nervous system and forms high density lipoprotein (HDL) like lipoprotein. ApoE is primarily secreted by astrocytes in the central nervous system and is thought to play an important role in cholesterol and lipid transport. The APOE gene has three major alleles, APOE2, APOE3, and APOE4. These alleles encode for 3 common APOE protein isoforms, ApoE2, ApoE3, and ApoE4. APOE3 is most common isoform of APOE with the other two isoforms differing by the loss (ApoE4, Cys112Arg) or gain (ApoE2, Arg158Cys) of a cysteine residue. APOE4 is the largest risk factor …

Go to article

Intragenic Egfr::Egfre1e8 Fusion (Egfrviii) In 4331 Solid Tumors, Lan Zheng, Rajyalakshmi Luthra, Hector A Alvarez, F Anthony San Lucas, Dzifa Y Duose, Ignacio I Wistuba, Gregory N Fuller, Leomar Y Ballester, Sinchita Roy-Chowdhuri, Keith J Sweeney, Asif Rashid, Richard K Yang, Wei Chen, Audrey Liu, Yun Wu, Constance Albarracin, Keyur P Patel, Mark J Routbort, Aysegul A Sahin, Qingqing Ding, Hui Chen Dec 2023

Intragenic Egfr::Egfre1e8 Fusion (Egfrviii) In 4331 Solid Tumors, Lan Zheng, Rajyalakshmi Luthra, Hector A Alvarez, F Anthony San Lucas, Dzifa Y Duose, Ignacio I Wistuba, Gregory N Fuller, Leomar Y Ballester, Sinchita Roy-Chowdhuri, Keith J Sweeney, Asif Rashid, Richard K Yang, Wei Chen, Audrey Liu, Yun Wu, Constance Albarracin, Keyur P Patel, Mark J Routbort, Aysegul A Sahin, Qingqing Ding, Hui Chen

Faculty, Staff and Student Publications

Epidermal growth factor receptor variant III (EGFRvIII, the deletion of exons 2-7) is a recurrent intragenic EGFR::EGFR.E1E8 fusion that occurs in high-grade gliomas. The presence of EGFRvIII in other solid tumors has not been well characterized. We retrospectively reviewed advanced malignant solid tumor cases tested by a custom hybrid capture 610-gene next-generation sequencing platform from 2021 to 2022. EGFRvIII was identified in 17 of 4331 (0.4%) cases, including 16 of 238 (7%) brain tumors and 1/301 (0.3%) breast tumors. EGFRvIII-positive brain tumors were all glioblastoma IDH-wildtype, most with concurrent TERT promoter mutation (14 of 16), EGFR amplification (13 of …

Go to article

Blue-Shift Photoconversion Of Near-Infrared Fluorescent Proteins For Labeling And Tracking In Living Cells And Organisms, Francesca Pennacchietti, Jonatan Alvelid, Rodrigo A Morales, Martina Damenti, Dirk Ollech, Olena S Oliinyk, Daria M Shcherbakova, Eduardo J Villablanca, Vladislav V Verkhusha, Ilaria Testa Dec 2023

Blue-Shift Photoconversion Of Near-Infrared Fluorescent Proteins For Labeling And Tracking In Living Cells And Organisms, Francesca Pennacchietti, Jonatan Alvelid, Rodrigo A Morales, Martina Damenti, Dirk Ollech, Olena S Oliinyk, Daria M Shcherbakova, Eduardo J Villablanca, Vladislav V Verkhusha, Ilaria Testa

Faculty, Staff and Student Publications

Photolabeling of intracellular molecules is an invaluable approach to studying various dynamic processes in living cells with high spatiotemporal precision. Among fluorescent proteins, photoconvertible mechanisms and their products are in the visible spectrum (400-650 nm), limiting their in vivo and multiplexed applications. Here we report the phenomenon of near-infrared to far-red photoconversion in the miRFP family of near infrared fluorescent proteins engineered from bacterial phytochromes. This photoconversion is induced by near-infrared light through a non-linear process, further allowing optical sectioning. Photoconverted miRFP species emit fluorescence at 650 nm enabling photolabeling entirely performed in the near-infrared range. We use miRFPs as …

Go to article

Extended-Synaptotagmin-1 And -2 Control T Cell Signaling And Function, Nathalia Benavides, Claudio G. Giraudo Dec 2023

Extended-Synaptotagmin-1 And -2 Control T Cell Signaling And Function, Nathalia Benavides, Claudio G. Giraudo

Department of Microbiology and Immunology Faculty Papers

Upon T-cell activation, the levels of the secondary messenger diacylglycerol (DAG) at the plasma membrane need to be controlled to ensure appropriate T-cell receptor signaling and T-cell functions. Extended-Synaptotagmins (E-Syts) are a family of inter-organelle lipid transport proteins that bridge the endoplasmic reticulum and the plasma membrane. In this study, we identify a novel regulatory mechanism of DAG-mediated signaling for T-cell effector functions based on E-Syt proteins. We demonstrate that E-Syts downmodulate T-cell receptor signaling, T-cell-mediated cytotoxicity, degranulation, and cytokine production by reducing plasma membrane levels of DAG. Mechanistically, E-Syt2 predominantly modulates DAG levels at the plasma membrane in resting-state …

Go to article

Power And Knowledge In Policy Evaluation: From Managing Budgets To Analyzing Scenarios, Frank Pasquale Dec 2023

Power And Knowledge In Policy Evaluation: From Managing Budgets To Analyzing Scenarios, Frank Pasquale

Law and Contemporary Problems

No abstract provided.

Go to article

Needle Biopsy Accelerates Pro-Metastatic Changes And Systemic Dissemination In Breast Cancer: Implications For Mortality By Surgery Delay, Hiroyasu Kameyama, Priya Dondapati, Reese Simmons, Macall Leslie, John Langenheim, Yunguang Sun, Misung Yi, Aubrey Rottschaefer, Rashmi Pathak, Shreya Nuguri, Kar-Ming Fung, Shirng-Wern Tsaih, Inna Chervoneva, Hallgeir Rui, Takemi Tanaka Dec 2023

Needle Biopsy Accelerates Pro-Metastatic Changes And Systemic Dissemination In Breast Cancer: Implications For Mortality By Surgery Delay, Hiroyasu Kameyama, Priya Dondapati, Reese Simmons, Macall Leslie, John Langenheim, Yunguang Sun, Misung Yi, Aubrey Rottschaefer, Rashmi Pathak, Shreya Nuguri, Kar-Ming Fung, Shirng-Wern Tsaih, Inna Chervoneva, Hallgeir Rui, Takemi Tanaka

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

ncreased breast cancer (BC) mortality risk posed by delayed surgical resection of tumor after diagnosis is a growing concern, yet the underlying mechanisms remain unknown. Our cohort analyses of early-stage BC patients reveal the emergence of a significantly rising mortality risk when the biopsy-to-surgery interval was extended beyond 53 days. Additionally, histology of post-biopsy tumors shows prolonged retention of a metastasis-permissive wound stroma dominated by M2-like macrophages capable of promoting cancer cell epithelial-to-mesenchymal transition and angiogenesis. We show that needle biopsy promotes systemic dissemination of cancer cells through a mechanism of sustained activation of the COX-2/PGE2/EP2 feedforward loop, …

Go to article

Sustainable Solution For Plastic Waste Management And Education Campaigns To Mitigate Plastic Consumption And Foster Behavior Change, Mayowa Akande Dec 2023

Sustainable Solution For Plastic Waste Management And Education Campaigns To Mitigate Plastic Consumption And Foster Behavior Change, Mayowa Akande

Masters Theses

The issue of plastic waste has become a significant environmental concern in contemporary times. Given the escalating rates of plastic production and consumption worldwide, an urgent need is to implement effective strategies to manage plastic waste. This article aims to investigate sustainable strategies for managing plastic waste through an analysis of existing research and exemplary approaches in the domain. This research assesses diverse methodologies, such as recycling, waste minimization, biodegradable substitutes, and policy interventions, and appraises their efficacy, obstacles, and prospects for enduring sustainability. The results of this research emphasize the significance of inclusive and cohesive approaches that engage various …

Go to article

Visualizing The Risks: The Significance Of Graphic Design In Educating Women About The Risks Of Prescription Opioids & Pre-Existing Mental Health Conditions, Natascha Foret Truong Dec 2023

Visualizing The Risks: The Significance Of Graphic Design In Educating Women About The Risks Of Prescription Opioids & Pre-Existing Mental Health Conditions, Natascha Foret Truong

Masters Theses

This thesis explores the critical issue of educating women about the increased risks of prescription opioid use and misuse relating to a co-occurring mental health illness. The research-based graphic design solutions proposed in the thesis aim to create awareness and provide knowledge to women on this matter. It is imperative to address this issue as it has severe consequences for women, their families, and society. This thesis utilizes research and best practices from scholarly articles, case studies, visual analysis, personas, and mind mapping to present graphic design solutions based on evidence. These solutions aim to educate women about the gender-specific …

Go to article

Biodegradable Magnesium Alloys For Biomedical Implants: Properties, Challenges, And Surface Modifications With A Focus On Orthopedic Fixation Repair, Kevin Koshy Thomas, Mah Noor Zafar, William G. Pitt, Ghaleb A. Husseini Dec 2023

Biodegradable Magnesium Alloys For Biomedical Implants: Properties, Challenges, And Surface Modifications With A Focus On Orthopedic Fixation Repair, Kevin Koshy Thomas, Mah Noor Zafar, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Biomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for people with bone-related ailments. While these materials have been successfully used in orthopedic applications, concerns including stress-shielding have necessitated the exploration of alternative solutions. An ideal biomedical implant requires a delicate balance of mechanical performance, corrosion resistance, tissue biocompatibility, and other properties such as tribological performance and osseointegration. This review explores the suitability of biodegradable magnesium (Mg) alloys as a promising material for biomedical implants. It delves into the essential properties of biomedical implants, emphasizing the importance of matching mechanical characteristics …

Go to article

With Or Without The Table, We Gather: Reinforcing Innate Resiliencies In The African American Family, Jessica L. Stevens-Eddy Dec 2023

With Or Without The Table, We Gather: Reinforcing Innate Resiliencies In The African American Family, Jessica L. Stevens-Eddy

Doctoral Dissertations and Projects

This quantitative study aims to determine whether food-sharing (gathering to eat) can be considered a suitable medium to facilitate increased cohesion within African American families. This study focuses on informal food-sharing as an extension of formal meal-sharing. Previous research links consistent formal meal-sharing to positive and secure identity development, better familial attachment, and improved family cohesion. These practices leave a lasting, detrimental impact on the African American family model. Additional barriers to some African American family meal-sharing practices include working extended and atypical work hours, food insecurity, and poor familial communication. There is a lack of research concerning the impact …

Go to article

Mindfulness For The Reduction Of Anxiety, Stress, And Depression In The Preservice Teacher Community, Shelley R. Crampton Dec 2023

Mindfulness For The Reduction Of Anxiety, Stress, And Depression In The Preservice Teacher Community, Shelley R. Crampton

Doctoral Dissertations and Projects

Teachers and students alike suffer from anxiety, stress, and depression. Mindfulness-based strategies have been indicated to help teachers and students deal with stress, anxiety, and depression. Teachers often report not wishing to add more learning strategies to their packed schedules and workload. Education in mindfulness is not easily accessible due to the time constraints of this overworked population. The criteria for participation in the study required the college students in preservice education classes to be over 18 years old, enrolled in the teacher education program, and not have participated in any mindfulness in the last six months. The study is …

Go to article

The Impact Of Moral Injury On Character Identity For Divorced Catholics: A Character Domain Perspective, Mary Susan Mcauliff Dec 2023

The Impact Of Moral Injury On Character Identity For Divorced Catholics: A Character Domain Perspective, Mary Susan Mcauliff

Doctoral Dissertations and Projects

Catholics who are faithful to the teachings of the Catholic Church on the indissolubility of marriage and who experience a civil divorce are at high risk for moral injury. This study was anchored on a character domain theoretical framework, and it investigated the impact of moral injury on character identity (measured by self-discrepancy) through the mediation of the perception of suffering. Religiosity was explored as a moderator for the relationships of moral injury to perception of suffering, perception of suffering to character identity, and moral injury to character identity. Participants (N = 251) were recruited from social media groups, various …

Go to article

A Phenomenological Study Of African-American Clergys’ Experiences With Mental Health, Rosalind R. Smith Dec 2023

A Phenomenological Study Of African-American Clergys’ Experiences With Mental Health, Rosalind R. Smith

Doctoral Dissertations and Projects

The purpose of this hermeneutical phenomenological qualitative study was to describe African-American clergy’s lived experiences with mental health and mental health’s influence on the construction of their teachings, sermons, and church practice. The goal was to use interpretation to bring to light to an underlying coherence of actions of a group of people. This study reduced individual African-American clergy beliefs regarding mental health to a universal understanding. There were four philosophical assumptions in this study: 1) a search for wisdom to understand the phenomenon of African-American clergy’s lived experiences with mental health influence their teachings, sermons, and church practice, 2) …

Go to article

Beyond Acculturation And Resilience: International Students Navigating Shame And Self-Concept, Shauna Thompson Dec 2023

Beyond Acculturation And Resilience: International Students Navigating Shame And Self-Concept, Shauna Thompson

Doctoral Dissertations and Projects

This study highlights the unique experiences of international students while they pursue higher education, manage adjustment issues, and navigate internal struggles. To explore whether English proficiency and family expectations correlate with self-concept and acculturation resilience, this study focused on the acculturation process, incorporating aspects of shame and self-concept that contribute to a student’s motivation and resilience. International students commonly face academic and personal challenges while adjusting to an environment that requires fluency in English. Additionally, many experience the pressure of high expectations from their families in their countries of origin. This study used a sociocultural approach to explore how international …

Go to article

How Does Nurse-To-Patient Ratio Impact Patient Outcomes In Adults, 18 Years And Older, That Are Admitted To Hospitals Around The World: An Integrative Review, Bre' Bryant Dec 2023

How Does Nurse-To-Patient Ratio Impact Patient Outcomes In Adults, 18 Years And Older, That Are Admitted To Hospitals Around The World: An Integrative Review, Bre' Bryant

Doctoral Dissertations and Projects

The field of nursing, known as the heart of health care, impacts individuals throughout every season of life: from the first cry to the last breath. It matters not how advanced the world might become; the calming presence of a nurse is irreplaceable. Considering the value of nurses, adequate work settings and staffing ratios is essential for care provision. Current practice is lacking, focusing heavily on patient satisfaction while staff contentment is not always addressed. Ratios are being increased, changing the way nurses provide care. The industry calls nurses into action to provide care that is efficient, effective, and safe. …

Go to article

Exploring The Need For Additional Title Ix Education And Training, Maria K. Lamiotte Dec 2023

Exploring The Need For Additional Title Ix Education And Training, Maria K. Lamiotte

Doctoral Dissertations and Projects

This quantitative study explores the differences between students, faculty, and staff about the need for additional Title IX education and training at a community college in Southeastern Connecticut from the four-level construct of the Social-Ecological Model of sexual misconduct prevention. This paper analyzed the existing literature on sexual misconduct education and training across higher education institutions, specifically related to community colleges nationwide. The literature was limited, related to community colleges. The data analysis explored the differences between students, faculty, and staff’s gender, sexual orientation, and college status about the need for additional Title IX education and training using archival data …

Go to article

Apologetic Knowledge: The Modern Church Planter, Matthew Dilley Dec 2023

Apologetic Knowledge: The Modern Church Planter, Matthew Dilley

Doctoral Dissertations and Projects

This project addresses a critical need within the ministry field, focusing on pastors affiliated with the church planting networks Excel Leadership Network and Transformation Ministries. The context is shaped by the COVID-19 pandemic's impact on church planting, with a shift to online services and emerging challenges in ministry. The problem is the significant lack of knowledge of apologetics among church planters, hindering their ability to effectively articulate and defend the Christian faith in today's postmodern world, particularly when engaging with non-believers. This DMIN action research project aims to create a concise video curriculum that equips pastors with fundamental apologetics knowledge. …

Go to article

Intimate Partner Violence And Spirituality: A Healing Process, Sheila Diane Lundquist Dec 2023

Intimate Partner Violence And Spirituality: A Healing Process, Sheila Diane Lundquist

Doctoral Dissertations and Projects

The purpose of this qualitative phenomenological study is to understand how intimate partner violence (IPV) survivors, from the Atlanta area, use spirituality to heal from the abuse. The theory guiding this study is Maslow’s (1954) Hierarchy of Needs as it shows how spirituality helped these women meet the needs on the hierarchy after having many of the needs ripped from them by the perpetrator(s). Intimate partner violence is a fundamental problem in the United States, especially during these times of COVID-19 and the stay-at home orders. Intimate partner violence takes a toll on the family unit, the community, and the …

Go to article

The Impact Of Shame On Medication-Assisted Therapy Treatment Outcomes For Individuals With A Severe Opiate Use Disorder, Cameron Davis Mcclure Dec 2023

The Impact Of Shame On Medication-Assisted Therapy Treatment Outcomes For Individuals With A Severe Opiate Use Disorder, Cameron Davis Mcclure

Doctoral Dissertations and Projects

Shame has a significant impact on various psychopathologies including depression (Pinto et al., 2012), anxiety, and posttraumatic stress disorder (Bryan et al., 2013). The gap in this research is the quantitative impact of shame on the relapse cycle in individuals with a severe opioid use disorder. This research study will demonstrate the impact of shame on the expression of addictive behavior in patients that have a diagnosed opiate use disorder and are currently actively enrolled in a medication-assisted therapy treatment program. This research study will illustrate how the presence of increased therapeutic alliance strength can result in the reduction of …

Go to article

The Necessity Of Spiritual Preparation In Short-Term Missions As It Correlates To Ministry Effectiveness, Brent Edward Allen Dec 2023

The Necessity Of Spiritual Preparation In Short-Term Missions As It Correlates To Ministry Effectiveness, Brent Edward Allen

Doctoral Dissertations and Projects

There is a lack of resources available providing spiritual preparation training specifically for teams preparing for a STM with M4 Institute. The purpose of this action research project is two-fold. First, to develop a spiritual preparation resource for STM work in the Western Highlands of Guatemala. Second, to determine if providing spiritual preparation training for a team preparing for said STM work will improve the ministry effectiveness of the trip. An eight-week, five-phase intervention guide was created to implement with the focus group. This consisted of two in-person, on-site team trainings, three pre-trip Zoom team meetings, mid-trip communications with participants …

Go to article

An Integrated Approach To Developing Pastoral Efficacy For Addiction Crisis Ministry, Matthias Ponce-De-Leon Dec 2023

An Integrated Approach To Developing Pastoral Efficacy For Addiction Crisis Ministry, Matthias Ponce-De-Leon

Doctoral Dissertations and Projects

The current addiction epidemic has heightened human suffering in many ways globally. This action research project built and implemented a training system to prepare pastors for encounters with individuals and families in substance addiction crises. The primary focus of the training system was to integrate existing approaches to pastoral equipping while advancing the theological framing of addiction models. In doing so, pastors developed understanding and confidence for facing the logistical, personal, and theological challenges in ministry to addicts and their families. Twelve pastors participated in the designed intervention, a 3-hour training workshop, and their shifts in perspectives and strategies for …

Go to article

Perceived Problems And Advantages Associated With Teaching Band In Rural Northern New York, Joseph Charles Ianaconi Dec 2023

Perceived Problems And Advantages Associated With Teaching Band In Rural Northern New York, Joseph Charles Ianaconi

Doctoral Dissertations and Projects

Teaching instrumental music in rural northern New York presents unique advantages and problems for music educators. While most research highlights obstacles to teaching in a rural area, this study identifies the unique positive aspects of working in this environment. Educators often overlook the opportunities and benefits within small, rural schools. Directors and students can define and find success in multiple ways within these rural band programs. This qualitative study examines the opinions, feelings, and experiences of those who teach band in rural northern New York. The research focuses on the perceived advantages of directing an instrumental ensemble in a rural …

Go to article

A Phenomenological Approach Of Foster Parent Factors That Predict Placement Disruption Of Children In Foster Care, Latoya Ebony Moore Dec 2023

A Phenomenological Approach Of Foster Parent Factors That Predict Placement Disruption Of Children In Foster Care, Latoya Ebony Moore

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to discover foster parent factors contributing to foster care disruptions. Disruptions of foster care children are detrimental to the safety and well-being of the children. There are implications of foster care disruptions producing short- and long-term negative outcomes for children and families. Research indicates the emotional trauma effects of placement instability negatively impact the child’s relationships, ability to form attachments, educational outcomes, and mental and developmental stability. Foster parent factors have been identified that predict the likelihood of the parents disrupting the child’s placement and strategies for increasing placement stability in various studies. …

Go to article

Synthesis, Characterization, And Bslt Test Of Pyrazoline And Pyrazole Compounds From Chalcone Using Microwave Irradiation, Siska Elisahbet Sinaga, Matius Paundanan, Yum Eryanti Dec 2023

Synthesis, Characterization, And Bslt Test Of Pyrazoline And Pyrazole Compounds From Chalcone Using Microwave Irradiation, Siska Elisahbet Sinaga, Matius Paundanan, Yum Eryanti

Chimica et Natura Acta

Pyrazole is an organic compound, classified as an alkaloid, featuring a heterocyclic five-membered ring structure composed of three carbon atoms and two adjacent nitrogen atoms, forming an endocyclic double bond. Pyrazole has various biological activities, such as antibacterial, anticanc er, antiinflammatory, antidepressantion, and antioxidant. Pyrazole 2-(5-(4-chlorophenil)-1-phenil-1H-pyrazole-3il)phenol (TFP-2OH-4Cl) was synthesized via oxidative aromatization reaction of pyrazoline 2-(5-(4-chlorophenil)-1-phenil-4,5-dihydro-1H-pyrazole-3-il)phenol (PF-2OH-4Cl) with glacial acetic acid. Chalcone, pyrazoline, and pyrazole were synthesized using the microwave at 180 W at 85oC. The purity of the compounds was monitored on TLC plates, melting point, and HPLC analysis. The structure of synthesized compounds was confirmed by UV, FTIR, …

Go to article

Tempe Kedelai Hitam (Glycine Soja) Dan Kacang Buncis Putih (Phaseolus Vulgaris L.) Sebagai Pangan Fungsional Antioksidan, Sri Yadial Chalid, Anna Muawanah, Nani Radiastuti, Sofia Ade Putri, Fitriah Hartiningsih, Tarso Rudiana Dec 2023

Tempe Kedelai Hitam (Glycine Soja) Dan Kacang Buncis Putih (Phaseolus Vulgaris L.) Sebagai Pangan Fungsional Antioksidan, Sri Yadial Chalid, Anna Muawanah, Nani Radiastuti, Sofia Ade Putri, Fitriah Hartiningsih, Tarso Rudiana

Chimica et Natura Acta

Kedelai hitam dan biji kacang buncis mengandung senyawa flavonoid dan fenolik yang berpotensi dikembangkan sebagai pangan fungsional antioksidan. Campuran kedelai hitam dan biji kacang buncis putih 1:1 difermentasi dengan ragi tempe 0,2% (b/b) dan angkak divariasikan sebesar 1; 1,5; 2% (b/b) dengan waktu fermentasi 0, 12, dan 24 jam. Jumlah angkak dan waktu fermentasi optimum ditentukan berdasarkan karakteristik tempe dari uji organoleptik meliputi warna, bau, dan tekstur tempe oleh 25 orang panelis. Tempe diekstrak menggunakan aseton 80% (v/v) dan diukur aktivitas antioksidan dengan metode 2,2-diphenyl-1-picryhydrazyl (DPPH) serta total fenolik dan total flavonoid. Hasil uji organoleptik menunjukkan bahwa fermentasi selama 24 …

Go to article

Perbandingan Kadar Magnesium Pada Air Minum Dalam Kemasan (Amdk) Menggunakan Metode Spektrofotometri Dan Kompleksometri, Edy Agustian Yazid, Abdul Wafi, Roihatul Zahroh, Nurul Azizah Dec 2023

Perbandingan Kadar Magnesium Pada Air Minum Dalam Kemasan (Amdk) Menggunakan Metode Spektrofotometri Dan Kompleksometri, Edy Agustian Yazid, Abdul Wafi, Roihatul Zahroh, Nurul Azizah

Chimica et Natura Acta

Magnesium (Mg) merupakan salah satu mineral penting dalam tubuh yang memiliki fungsi memelihara kesehatan jantung, tulang, mengatur kadar gula darah hingga membantu mengatasi stres. Kebutuhan magnesium diantaranya dapat dipenuhi melalui Air Minum Dalam Kemasan (AMDK). Tujuan penelitian ini adalah untuk mengetahui perbedaaan kadar magnesium pada AMDK menggunakan metode spektrofotometri dan kompleksometri. Melalui perbandingan kedua metode tersebut dapat diketahui aplikasi metode yang lebih praktis dan efisien. Penentuan magnesium secara spektrofotometri dilakukan dengan mengukur terbentuknya senyawa kompleks Mg-EBT menggunakan spektrofotometer visibel pada panjang gelombang maksimum 530 nm. Hasil penelitian kadar magnesium pada AMDK metode spektrofotometri didapatkan kadar antara 1,5-19,45 mg/L, sedangkan dengan …

Go to article

The Impact Of Blood Cupping (Al-Hijama) On Serum Creatinine And Uric Acid Levels In Patients From Hadhramout, Yemen, Saleh Bin Sumaidea, Hassan Pyar Ali Hassan, Adnan Ali Bakaduem, Abdulrahman Omar Almashjari, Abdullah Shamlan Bashumail, Mohammed Saeed Blhamed Dec 2023

The Impact Of Blood Cupping (Al-Hijama) On Serum Creatinine And Uric Acid Levels In Patients From Hadhramout, Yemen, Saleh Bin Sumaidea, Hassan Pyar Ali Hassan, Adnan Ali Bakaduem, Abdulrahman Omar Almashjari, Abdullah Shamlan Bashumail, Mohammed Saeed Blhamed

Chimica et Natura Acta

Cupping is a wonderful healing tool that has been employed for hundreds of years by numerous traditional folklore practitioners. Cupping treats many diseases including eliminating blood pollutants like uric acid and creatinine. The aim of this study to evaluate the impact of cupping on blood pressure, uric acid concentration, and creatinine levels. Sixty (60) random patient between the ages of (20 -70) years were selected, the blood samples were collected before cupping and after cupping for the evaluation. The result showed that the levels of creatinine and uric acid decreased significantly (p < 0.05) after cupping for both creatinine and uric acid. Moreover, the study showed that blood pressure decreased significantly (p < 0.05) after cupping. The result concluded that cupping has positive impact on health by modulating creatinine, uric acid blood levels and decreasing blood pressure.

Go to article

A Quantum Physics-Based Force Field For Biomolecular Simulation, Roseane Dos Reis Silva Dec 2023

A Quantum Physics-Based Force Field For Biomolecular Simulation, Roseane Dos Reis Silva

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation explores the development of a physics-based force field meticulously tailored to guide molecular dynamics simulations of biomolecules. At its core, the Hydrogen-like Intermolecular Polarizable Potential (HIPPO) force field emerges as an apex of achievement, devised to refine the precision of short-range intermolecular interactions. HIPPO's inception marks a profound stride towards heightened realism in molecular simulations, anchored in Quantum Physics theory and fortified by state-of-the-art Quantum Chemistry calculations. This force field's efficacy is attested by its systematic application in constructing models featuring diverse organic molecules, from water to benzene, and those with motifs resembling proteins and nucleic acids. HIPPO …

Go to article

Biomarkers Of Affective Dysregulation Associated With In Utero Exposure To Etoh, Nune Darbinian, Nana Merabova, Gabriel Tatevosian, Mary Morrison, Armine Darbinyan, Huaqing Zhao, Laura Goetzl, Michael Edgar Selzer Dec 2023

Biomarkers Of Affective Dysregulation Associated With In Utero Exposure To Etoh, Nune Darbinian, Nana Merabova, Gabriel Tatevosian, Mary Morrison, Armine Darbinyan, Huaqing Zhao, Laura Goetzl, Michael Edgar Selzer

Faculty, Staff and Student Publications

INTRODUCTION: Children with fetal alcohol spectrum disorders (FASD) exhibit behavioral and affective dysregulation, including hyperactivity and depression. The mechanisms are not known, but they could conceivably be due to postnatal social or environmental factors. However, we postulate that, more likely, the affective dysregulation is associated with the effects of EtOH exposure on the development of fetal serotonergic (5-HT) and/or dopaminergic (DA) pathways, i.e., pathways that in postnatal life are believed to regulate mood. Many women who use alcohol (ethanol, EtOH) during pregnancy suffer from depression and take selective serotonin reuptake inhibitors (SSRIs), which might influence these monoaminergic pathways in the …

Go to article

First Prev Next Last