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A Journey From Univariate To Multivariate Functional Time Series: A Comprehensive Review, Hossein Haghbin, Mehdi Maadooliat

Mathematical and Statistical Science Faculty Research and Publications

Functional time series (FTS) analysis has emerged as a potent framework for modeling and forecasting time-dependent data with functional attributes. In this comprehensive review, we navigate through the intricate landscape of FTS methodologies, meticulously surveying the core principles of univariate FTS and delving into the nuances of multivariate FTS. The journey commences with an exploration of the foundational aspects of univariate FTS analysis. We delve into representation, estimation, and modeling, spotlighting the effectiveness of various parametric and nonparametric models at our disposal. The stage then transitions to multivariate FTS analysis, where we confront the intricacies posed by high-dimensional data. We …

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Human–Wildlife Interactions

This is the table of contents.

Pandemics Of Limitation Of Rights, Rinat Kitai-Sangero

Touro Law Review

This Article discusses the limitation of rights due to pandemics. It analyzes from a constitutional standpoint the holding of the German Federal Constitutional Court (Das BUNDESVERFASSUNGSGERICHT) from April 2022 as a symptom of moral panic disguised through an analytical process. Though it focuses on this case, it sheds light on the moral panic that characterized many countries’ approaches during the COVID-19 pandemic. On April 27, 2022, the German Federal Constitutional Court held that a provision to provide proof of vaccination against COVID-19, recovery from COVID-19, or a medical exemption to COVID-19 vaccination as a condition of employment in the health …

Table Of Contents

Touro Law Review

No abstract provided.

Durability, Flexibility And Plasticity In The U.N. Convention On The Law Of The Sea, Sean Murphy

GW Law Faculty Publications & Other Works

The overall resilience of the U.N. Convention on the Law of the Sea during the forty years since its adoption in 1982—its durability, its flexibility and its plasticity in the face of myriad challenges that have unfolded over time—is largely attributable to certain design features within the Convention, to a willingness to ‘bend’ the Convention toward practical outcomes when necessary, and to the foresight of the drafters in closely tying the Convention to other agreements and standards, as well as to the general field of international law, so that the Convention might evolve as the world evolves. There are risks …

The Battle Over Gender-Affirming Healthcare For Transgender Minors: Analyzing Anti-Transgender Healthcare Bills In Arkansas And Texas, Brandon Calton

Roger Williams University Law Review

No abstract provided.

Characterization Of Tonneau1 Recruiting Motif Proteins And Ton2 Signaling Functions, Tyler Falk

Theses and Dissertations

Plants cells are fixed in place. As a result they have to carefully divide in order to function properly. Plants use a number of complex microtubule arrays to ensure proper division and orientation including the preprophase band (PPB) and the phragmoplast. The PPB orients the cell prior to division and marks the cortical division site, which is where the phragmoplast is guided to. The phragmoplast is a dynamic microtubule array that builds the cell plate which later becomes the cell wall that divides daughter cells. Proteins involved with PPB formation include Tonneau1 (TON1) and Tonneau2 (TON2) which localize to and …

Food For Thought: Fabricating The Cannibal In Colonization, Hannah Dubrovich

Theses and Dissertations

Anthropophagy means people-eating, as does cannibal, but the terms are not synonymous. After Europeans landed in the Americas, Christopher Columbus coined the word cannibal. Despite the two terms having similar base definitions, there are additional connotations associated with cannibal. The way in which cannibalism has been thought about by Western cultures is not about the act of people-eating, but the constructed character of the cannibal as a “savage” Other created through colonization. In addition to the term's associated meaning being cemented during this time, colonizers used the term as a tool to Other Native peoples and aid in colonization. It …

Ergot Alkaloid Consumption Alters Serotonin Receptor-Induced Vasoactivity In Ovine Umbilical Vasculature, James L. Klotz, Jessica L. Britt, Maslyn A. Greene, Coral Kent-Dennis, Susan K. Duckett

Animal and Food Sciences Faculty Publications

Consumption of ergot alkaloids during the second half of gestation has been shown to decrease umbilical artery vasoactivity resulting in decreased birth weights. Negative vascular effects of ergot alkaloids are mediated predominantly through serotonergic and adrenergic receptors in other tissues. Vasoactivity of serotonin (5-HT) receptors 5-HT_2A and 5-HT_1B/1D in umbilical artery and vein from ewes receiving endophyte-infected seed (E + 1.77 mg ergovaline/hd/d) or a control total mixed ration (CON; 0 mg ergovaline/hd/d) tall fescue seed at d-110 and d-133 of gestation was evaluated. Gravid reproduction tracts were collected from ewes. Two-mm sections of umbilical artery and vein …

Essential Oil Supplementation Improves Insulin Sensitivity And Modulates The Plasma Metabolome Of Hyperinsulinemic Horses, Caroline M.M. Loos, Shuang Zhao, Liang Li, Janet Li, Wei Han, Eric S. Vanzant, Kyle R. Mcleod

Animal and Food Sciences Faculty Publications

The objective of this study was to investigate the effect of essential oil (EO) supplementation on insulin sensitivity (IS) and the plasma metabolome in insulin dysregulated (ID) horses. Horses were blocked by degree of IS and assigned randomly to treatment: oral daily bolus (50 mL) of either a plant derived EO supplement or carrier (CON). Mares were housed in dry lots with ad libitum access to grass hay and supplemented individually twice daily with a concentrate to meet nutrient requirements for mature horses. Before and after 6 wks of treatment, mares underwent a combined glucose-insulin tolerance test (CGIT) and an …

Ovotransferrin-Depleted Egg White Hydrolysate Reduces Blood Pressure In Spontaneously Hypertensive Rats, Fatemeh Ashkar, Hongbing Fan, Zihan Wang, Ilekuttige Priyan Shanura Fernando, Jianping Wu

Animal and Food Sciences Faculty Publications

Egg whites contain a variety of biologically active proteins and are a good source of bioactive peptides. Egg white hydrolysate prepared by thermoase (EWH) possesses antihypertensive effects. Our recent study showed that egg white proteins, after depleting ovotransferrin, also contained many angiotensin-converting enzyme (ACE)-inhibitory peptides after hydrolysis using thermoase. In the present study, we aimed to explore the antihypertensive effect of the ovotransferrin-depleted egg white hydrolysate prepared by thermoase (OD-EWH) in spontaneously hypertensive rats, using EWH as the reference. The animals were orally administered with either hydrolysate at a dose of 1 g/kg body weight/d over 9 d. OD-EWH treatment …

Effects Of A Second Iron-Dextran Injection Administered To Piglets During Lactation On Differential Gene Expression In Liver And Duodenum At Weaning, James L. Pierce, J. Wesley Lyons, Tyler B. Chevalier, Merlin D. Lindemann

Animal and Food Sciences Faculty Publications

Six female littermate piglets were used in an experiment to evaluate the mRNA expression in tissues from piglets given one or two 1 mL injections of iron dextran (200 mg Fe/mL). All piglets in the litter were administered the first 1 mL injection < 24 h after birth. On day 7, piglets were paired by weight (mean body weight = 1.72 ± 0.13 kg) and one piglet from each pair was randomly selected as control (CON) and the other received a second injection (+Fe). At weaning on day 22, each piglet was anesthetized, and samples of liver and duodenum were taken from the anesthetized piglets and preserved until mRNA extraction. differential gene expression data were analyzed with a fold change cutoff (FC) of |1.2| P < 0.05. Pathway analysis was conducted with Z-score cutoff of P < 0.05. In the duodenum 435 genes were significantly changed with a FC ≥ |1.2| P < 0.05. In the duodenum, Claudin 1 and Claudin 2 were inversely affected by + Fe. Claudin 1 (CLDN1) plays a key role in cell-to-cell adhesion in the epithelial cell sheets and was upregulated (FC = 4.48, P = 0.0423). Claudin 2 (CLDN2) is expressed in cation leaky epithelia, especially during disease or inflammation and was downregulated (FC = -1.41, P = 0.0097). In the liver, 362 genes were expressed with a FC ≥ |1.2| P < 0.05. The gene most affected by a second dose of 200 mg Fe was hepcidin antimicrobial peptide (HAMP) with a FC of 40.8. HAMP is a liver-produced hormone that is the main circulating regulator of Fe absorption and distribution across tissues. It also controls the major flows of Fe into plasma by promoting endocytosis and degradation of ferroportin (SLC4A1). This leads to the retention of Fe in Fe-exporting cells and decreased flow of Fe into plasma. Gene expression related to metabolic pathway changes in the duodenum and liver provides evidence for the improved feed conversion and growth rates in piglets given two iron injections preweaning with contemporary pigs in a companion study. In the duodenum, there is a downregulation of gene clusters associated with gluconeogenesis (P < 0.05). Concurrently, there was a decrease in the mRNA expression of genes for enzymes required for urea production in the liver (P < 0.05). These observations suggest that there may be less need for gluconeogenesis, and possibly less urea production from deaminated amino acids. The genomic and pathway analyses provided empirical evidence linking gene expression with phenotypic observations of piglet health and growth improvements.

Role Of Ε-Poly-Lysine In Mixed Surimi Gel, Zhaorui Li, Guangcan Liang, Yungang Cao, Fang Yuan, Miaomiao Liu, Zelong Liu, Youling L. Xiong

Animal and Food Sciences Faculty Publications

The effects of different concentrations of ε-Poly-lysine (ε-PL: 0.005%, 0.01%, 0.02%, 0.04%, and 0.06%) on the marine fish-egg white protein compound gels, treated with 0.4% TGase induced cross-linking were systematically investigated under low salt and phosphorus-free conditions (0.5% NaCl). The results showed the combination of ε-PL and TGase had a synergistic effect on improving sectional gel properties of composite surimi samples. Wherein the rheological, LF-NMR, and SEM results confirmed that the addition of ε-PL based on 0.4% TGase significantly improved the gel strength (to the highest value: 781.63 g·cm), apparent viscosity, and G 'value of the composite surimi sample, as …

The Impact Of Daylight Saving Time Transitions On Domestic Violence Call Volume, Quynh-Nhu Pham

Master's Projects

Daylight Saving Time (DST) is a longstanding practice in many countries, involving the seasonal adjustment of clocks by one hour forward in the spring, and one hour backward in the fall. Although DST was initially introduced to promote energy conservation and maximize daylight hours, it has become a subject of debate, given its impact on physical and mental health, cognitive performance, and criminal behavior (Kountouris & Remoundou, 2014).

In 2022, Colorado enacted a law adopting year-round DST, contingent upon a federal law enabling states to maintain DST throughout the year as opposed to ST, like Hawaii and Arizona (Chasan, 2024). …

How Are Mcps Doing On Achieving Assessed Calaim Requirements? A Comparative Analysis Of Selected Not-For-Profit, Publicly Governed Health Plans In California, Junell Chen

Master's Projects

At the heart of a larger societal movement, the imperative to foster diversity, equity, and inclusion (DEI) is a resounding call to action across all sectors. This pressing concern underscores the need for proactive and equity-centric solutions, including within the American healthcare system. The U.S. Department of Health and Human Services has been instrumental in shaping policies and initiatives, such as Healthy People, aimed at promoting health equity and reducing health disparities. Similarly, the Centers for Medicare and Medicaid Services (CMS) has instituted supplementary compliance requirements to hold healthcare stakeholders accountable for implementing equitable programs designed to eliminate health disparities …

The 1-Back Matching/Mismatching Paradigm With Pigeons (Columba Livia): Evidence For Explicit Learning?, Daniel Peng

Theses and Dissertations--Psychology

With humans, a distinction can be made between explicit and implicit learning. language can be used to describe rule-based learning commonly seen in explicit, but not implicit learning. Unfortunately, we cannot do so with animals. Therefore, a non-verbal paradigm is needed to differentiate the types of learning. One method to make such a distinction is by training animals under a conditional discrimination task such as matching-to-sample with reinforcement delayed until a choice is made on the next trial: otherwise known as a 1-back procedure. In this experiment an alternating matching/mismatching to sample task under a 1-back schedule of reinforcement was …

Neural Hyperactivity During Value-Based Decision-Making In People With Daily/Near Daily Cannabis Use, Miranda Ramirez

Theses and Dissertations--Psychology

Value-based decision-making involves the coordinated effort of multiple brain regions to guide future choices based on past experiences. These processes are disrupted in cannabis use disorder, where individuals continue to use cannabis despite negative consequences. Reinforcement learning (RL) paradigms can be used to capture changes in the value of available options and may inform how the brain is impacted by frequent cannabis use. This study combined fMRI with behavioral modeling of probabilistic choice task data to compare value-based choices between young adults reporting daily/near daily cannabis use (CAN) and controls (CTRL). Participants selected one of two options reinforced ($0.25) at …

Effect Of A Brief Coping Intervention On Activity Of Target Organs Of The Sympathetic And Parasympathetic Nervous Systems During Stress, Kyle P. Rawn

Theses and Dissertations--Psychology

Stress is a critical aspect of the human experience and how an individual responds to stress can shape future outcomes, such as physical and mental health, as well as shape the patterns of stress responding that persist throughout one’s lifespan. Coping is a central element of stress responding and can strongly influence the outcome of the stress process. Successful coping can alleviate stress, but ineffective coping may lead to less-than-optimal responding. For example, aspects of the biological stress response, such as activity of target organs for the sympathetic and parasympathetic nervous systems, have important implications for future susceptibility to health …

Influence Of Oral Contraceptives On Alcohol Use In Young Adult Women, Ashley Strzelecki

Theses and Dissertations--Psychology

Rates of heavy drinking and Alcohol Use Disorder are rising dramatically in young adult women, making it important to better understand female-specific risks for problematic drinking. Circulating levels of ovarian hormones are one potential mechanism influencing alcohol use in women. Many young adult women use oral contraceptives (OCs) that alter endogenous hormone levels, and little is known about how OCs and the synthetic hormones they contain may influence alcohol use. This dissertation consists of three studies that investigated alcohol consumption in women using OCs and explored potential mechanisms through which OCs may influence alcohol use. Study 1 compared self-reported alcohol …

It Takes A Village: Impact Of Lgbtq+ Community On The Relationship Between Parenting Stress, Parent Mental Health, And Child Adjustment, Kevin Mcaweeney

Theses and Dissertations--Psychology

While LGBTQ+ parented families are largely the same as their cis-het parent counterparts, they still experience unique factors exclusive to them. One such factor is access to the LGBTQ+ community. While research has emphasized the importance of community within the family system, the role the LGBTQ+ community can play for LGBTQ+ parented families is largely unexplored. Additionally, LGBTQ+ research examining parents of adolescents is similarly lacking. Utilizing a sample of LGBTQ+ parents with adolescent children, and informed by ecological systems theory, self-determination theory, and the parenting stress model, I examine the influence parent’s sense of LGBTQ+ community has on the …

Development Of The Trait Response To Emotion Dimensional Measure For Use In Minoritized Populations, Anita Adams

Theses and Dissertations--Psychology

Trait responses to emotion (TREs) are personality traits that develop from how one consistently responds to and copes with emotions. TRE development is influenced by demographic factors, such as age, gender, and early life adversity, and TREs can influence how one copes with a variety of stressors. TRE theory and measurement is relatively new, and although TREs have been validated in majority race samples, TRE theory and measurement have not been validated in minority race samples, particularly in African American populations. This dissertation is taking the first preliminary steps for the development of a cross-cultural trait response to emotion dimensional …

Hormonal Effects On Adhd Symptoms In Adolescents Across The Menstrual Cycle, Ashley G. Eng

Theses and Dissertations--Psychology

Background: Females with attention-deficit/hyperactivity disorder (ADHD) become particularly impaired during adolescence, experiencing increased rates of depression and anxiety, as well as important public and personal health outcomes like increased suicide attempts, risky sexual behavior, and substance use. However, female-specific risk factors for ADHD have been vastly understudied despite this increased impairment and comorbidity. One particularly understudied risk factor is the dramatically rising and fluctuating levels of ovarian hormones during late puberty that begin cycling monthly. In adult women, rapid decreases in estrogen levels increase risk for ADHD symptoms across the menstrual cycle, particularly for those with high trait impulsivity. Preliminary …

The Effect Of Cytomegalovirus Infection On Daily Stress Processes In Early Adulthood, Elana Gloger

Theses and Dissertations--Psychology

Chronic stress increases risk for disease, poor health, and early mortality. Cytomegalovirus (CMV), a common latent herpes virus, may promote neurological changes that increase vulnerability to chronic stress by way of self-regulatory deficits, though this has yet to be directly tested. Investigating CMV at younger ages is crucial to understand the effect of CMV across the lifespan and identify modifiable health-factors for future anti-aging interventions. The present study aimed to investigate how, and for whom, CMV associates with daily stress processes in early adulthood.

Participants (N = 108, M_age = 19.7, 83.3% female, 72% White) completed an in-person lab …

Fluctuations In Alcohol Impairment Of Working Memory Across The Menstrual Cycle, William Mcgarrigle

Theses and Dissertations--Psychology

Behavioral endocrinology studies in women suggest that higher circulating levels of the ovarian sex hormone estradiol (E2) may be linked to better working memory performance, especially under conditions of cognitive impairment (e.g., age-related cognitive decline). Phases of the menstrual cycle characterized by different levels of E2 may therefore influence the degree to which women are vulnerable to alcohol impairment of working memory. The current thesis used a within-subjects design to test the hypothesis that women are less sensitive to acute alcohol-induced impairment of working memory when E2 is elevated during the menstrual cycle. A sample of 75 premenopausal women completed …

Cognitive-Behavioral Effects And Sex Differences In Alcohol Use, Mia Radevski

Theses and Dissertations--Psychology

Addiction models (e.g., iRISA model) suggest that excessive substance use can result in behavioral consequences such as decreased response inhibition and increased salience attribution toward alcohol cues. The primary goal of this project was to explore potential sex differences in these characteristics of addiction. This dissertation is comprised of two separate but related studies. Study 1 investigated sex differences in inhibitory control and attentional bias. The central hypotheses are 1) women who reported heavy-drinking would display greater disruptions in behavioral inhibitory control following alcohol-related cues, 2) men who reported heavy-drinking would display greater attentional bias toward alcohol-related cues, and 3) …

Menstrual Cycle Phase And Hormonal Effects On Emotional Eating In Females With Attention-Deficit/Hyperactivity Disorder, Urveesha Nirjar

Theses and Dissertations--Psychology

Previous research has shown that cyclical fluctuations in ovarian hormones can predict changes in ADHD symptoms as well as eating behaviors, particularly emotional eating across the menstrual cycle. Previous studies have so far only examined the effects of estrogen (E2), progesterone (P4) and cycle phase in predicting individual symptoms or disorders such as ADHD or eating disorders or related behaviors separately. The aim of this study is to examine how emotional eating is influenced by naturally occurring hormonal and cycle changes in a sample overrecruited for ADHD. Seventy-eight individuals (assigned female at birth) with menstrual cycles overrecruited for ADHD provided …

Terror And Time: Analyzing Homegrown Terrorism In The United States, Kyser Daniels-Baessler

Theses and Dissertations

The events of September 11th, 2001, prompted a global reckoning with the threat of international terrorism, leading to intensified awareness and policy responses worldwide. However, amidst this heightened global focus, the United States has faced a concerning rise in politically motivated violence on its soil. Against this backdrop, this thesis delves into the phenomenon of homegrown terrorism within the United States from 2000 to 2020. By employing advanced geospatial techniques, this study seeks to pinpoint areas nationwide with elevated rates of homegrown terrorist incidents. Moreover, it endeavors to uncover potential temporal correlations between these acts of violence and significant events, …

Intimate Partner Violence And Parent Perceptions Of Their Emotional Bond To Their Children, Lia T. Mclanahan

Doctor of Psychology (PsyD)

As research on intimate partner violence (IPV) continues to grow and there are more ways of defining IPV and identifying its differing forms, a related topic of interest has become the impact IPV has on families (Fong et al., 2019). Similarly, research on IPV as a form of trauma and its implications is well-researched for both children and adults, as is the research on trauma and attachment (Cook et al., 2017). However, there seems to be a lack of research on how parent–child attachment is predicted by IPV. The present study aimed to assess how parent perceptions of their level …

An Empirical Predictive Model For Determining The Aqueous Solubility Of Bcs Class Iv Drugs In Amorphous Solid Dispersions, Sridivya Raparla

University of the Pacific Theses and Dissertations

Poor aqueous solubility persists as a significant challenge in the pharmaceutical industry.Ongoing research aims to enhance the solubility of drugs to deliver them more effectively. Amorphous solid dispersion (ASD) is a widely used solubility enhancement technique. The absence of a specific model to predict compound solubility from ASDs resulted in a trial-and- error approach to studying solubility enhancement and makes it a laborious and time-consuming process. Predictive models could streamline this process and accelerate the development of oral drugs with improved aqueous solubilities. This study aimed to develop a predictive model to estimate the solubility of a compound from the …

Understanding The Trafficking Of Children For The Purposes Of Labor In The United States, Amy Farrell, Meredith Dank, Katherine Kaufka Walts, Callie Hansson, Andrea Hughes, Chlece Neal

Center for the Human Rights of Children

No abstract provided.