Digital Commons Network^™

Roles Of Mtor Complex 2 Signaling In The Sphingolipid Production Of Brain Cancer Cell Lines, Nuanwan Songcharoen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Gliomas, which include low- and high-grade types, represent a particularly aggressive form of primary brain tumor, especially glioblastoma (GBM). Metabolic reprogramming in lipid metabolism supports cell proliferation; alterations in the sphingolipid pathway, elevated glucosylceramide (GlcCer) levels through glucosylceramide synthase (GCS), promote the production of glycosphingolipids, which serve as building blocks for cancer cells. Furthermore, mTORC2, which is a kinase protein, contributes to lipid metabolism. Thus, the study aims to investigate the roles of mTORC2 signaling in lipid metabolism through lipid accumulation, which was reduced with AZD8055 treatment as the mTORC2 inhibitor. Additionally, p-AKT (S473), which is downstream of mTORC2, was …

Effect Of Task Constraints On Neurobiological Systems Involved In Postural Control In Individuals With And Without Chronic Ankle Instability, Yuki A. Sugimoto, Patrick O. Mckeon, Christopher K. Rhea, Carl G. Mattacola

Rehabilitation Sciences Faculty Publications

The purpose of this study is to investigate the effect of task constraints on the neurobiological systems while maintaining postural control under various sensory feedback manipulations in individuals with and without Chronic Ankle Instability (CAI). Forty-two physically active individuals, with and without CAI, were enrolled in a case-control study conducted at a biomechanics research laboratory. All participants underwent the Sensory Organization Test (SOT), which assesses individuals’ ability to integrate somatosensory, visual, and vestibular feedback to maintain postural control in double-, uninjured-, and injured-limb stances under six different conditions in which variations in the sway-referenced support surface (platform) and visual surroundings, …

Perception, Awareness, And Practices Toward The Pm2.5 During The Air Pollution Episode Among Chinese Students In Bangkok And Vicinity, Thailand: A Cross-Sectional Study, Jiali Chen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Air pollution poses a significant public health threat to urban populations worldwide. Mobile groups such as international students face unique vulnerabilities, but their risk adaptation capacity remains understudied. This study assessed awareness, perception, and protective measures of PM2.5 among Chinese international students in Bangkok and its vicinity. This study used a validated scale to conduct a cross-sectional survey of 393 participants. The results revealed that while students exhibited a high level of risk perception regarding air pollution (mean score: 48.0 ± 7.6), their awareness was relatively low (mean score: 6.3 ± 2.9), with only 3.8% of respondents demonstrating "high awareness". …

Effects Of Water Chemistry On Interaction Between Organic Contaminants And Microplastics And Their Passage In Microfiltration Membrane, Chutiporn Inchana

Chulalongkorn University Theses and Dissertations (Chula ETD)

The agricultural activity is a critical source of organic contaminants and microplastics (MPs). Typically, the agricultural soil is contaminated by an abundance of MPs, leaching chemicals during weathering process, and pesticides, which subsequently end up in surface water through agricultural runoff. Polymers that are most frequently used in crop production and detected in surface water are PE and PET MPs. Bisphenol (A) and atrazine are frequently detected in surface water. Nevertheless, the fate and distribution of organic pollutants in water treatment as a consequent on MP-aided transport is constrained by little knowledge on photoaged PE and PET MPs. In this …

การพัฒนารูปแบบการเรียนรู้โมไบล์เลิร์นนิงแบบสืบสอบโดยใช้ปัญญาประดิษฐ์แบบรู้สร้างในการจับกลุ่มร่วมคิดเพื่อส่งเสริมการคิดอย่างมีวิจารณญาณของนักเรียนมัธยมศึกษาตอนปลาย, ธรรมทัศน์ สิงห์กา

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1) ศึกษาสภาพความเป็นจริง สภาพที่คาดหวัง และความต้องการจำเป็นในการพัฒนารูปแบบการเรียนรู้โมไบล์เลิร์นนิงแบบสืบสอบโดยใช้ปัญญาประดิษฐ์แบบรู้สร้างในการ จับกลุ่มร่วมคิดเพื่อส่งเสริมการคิดอย่างมีวิจารณญาณของนักเรียนมัธยมศึกษาตอนปลาย จากครูผู้สอนในกลุ่มสาระวิทยาศาสตร์และเทคโนโลยี ระดับชั้นมัธยมศึกษาตอนปลาย จำนวน 390 คน 2) พัฒนารูปแบบการเรียนรู้ฯ โดยสัมภาษณ์ความคิดเห็นผู้เชี่ยวชาญ จำนวน 5 คน 3) ศึกษาผลการใช้รูปแบบการเรียนรู้ฯ กับนักเรียน ชั้นมัธยมศึกษาปีที่ 4 จำนวน 34 คน ผลการวิจัยพบว่า . 1) สภาพความเป็นจริงในการพัฒนารูปแบบการเรียนรู้ฯ อยู่ในระดับมาก ค่าเฉลี่ยสูงสุด คือ ผู้สอนมีการแสดงให้เห็นถึงการเอาใจใส่ ให้คำชมเชย และเสริมแรงให้กับผู้เรียน (x̄ = 4.17, SD = 0.72) สภาพที่คาดหวังอยู่ในระดับมากที่สุด ค่าเฉลี่ยสูงสุด คือ ผู้สอนนำอุปกรณ์ อิเล็กทรอนิกส์ เข้ามาใช้ในการจัดการเรียนการสอน และผู้สอนมอบหมายงานได้สอดคล้องกับเนื้อหาบทเรียน (x̄ = 4.67, SD = 0.54) และความต้องการจำเป็นในการพัฒนารูปแบบการเรียนรู้ฯ ลำดับที่ 1 คือ ด้านการจัดกิจกรรมการเรียนการสอน ผู้สอนมอบหมายให้ผู้เรียนศึกษาเนื้อหาผ่านสื่อวิดีโอนอกชั้นเรียนก่อนทำกิจกรรมการเรียนการสอนในชั้นเรียน (PNIModified = 0.23) 2) รูปแบบการเรียนรู้ฯ ประกอบไปด้วย 6 องค์ประกอบ คือ ระบบจัดการเรียนรู้ที่สนับสนุนการเรียนผ่านอุปกรณ์เคลื่อนที่ เทคโนโลยีสนับสนุน ผู้อำนวยการเรียนรู้ ผู้เรียน กิจกรรมการเรียนรู้สืบสอบร่วมด้วยปัญญาประดิษฐ์แบบรู้สร้าง และการประเมินผล โดยมี 5 ขั้นตอน คือ (1) กระตุ้นความสนใจร่วมกับกิจกรรมคิดเดี่ยว (2) สำรวจและค้นคว้าร่วมกับกิจกรรมคิดเป็นคู่ด้วยปัญญาประดิษฐ์แบบรู้สร้าง (3) อธิบายและลงข้อสรุปร่วมกับกิจกรรมคิดเป็นกลุ่มด้วยปัญญาประดิษฐ์แบบรู้สร้างและกิจกรรมแบ่งปัน (4) ขยายความรู้ร่วมกับปัญญาประดิษฐ์แบบรู้สร้าง (5) ประเมิน . 3) ผลการใช้รูปแบบการเรียนรู้โมไบล์เลิร์นนิงแบบสืบสอบโดยใช้ปัญญาประดิษฐ์แบบรู้สร้างในการจับกลุ่มร่วมคิดเพื่อส่งเสริมการคิดอย่างมีวิจารณญาณของนักเรียนมัธยมศึกษาตอนปลาย พบว่า คะแนนการคิดอย่างมีวิจารณญาณหลังเรียนสูงกว่าก่อนเรียนอย่างมีนัยสำคัญที่ระดับ .05. .

Interpreting Neural Operators: How Nonlinear Waves Propagate In Non-Reciprocal Solids, Jonathan Colen, Alexis Poncet, Denis Bartolo, Vincenzo Vitelli

Data Science Faculty Publications

We present a data-driven pipeline for model building that combines interpretable machine learning, hydrodynamic theories, and microscopic models. The goal is to uncover the underlying processes governing nonlinear dynamics experiments. We exemplify our method with data from microfluidic experiments where crystals of streaming droplets support the propagation of nonlinear waves absent in passive crystals. By combining physics-inspired neural networks, known as neural operators, with symbolic regression tools, we generate the solution, as well as the mathematical form, of a nonlinear dynamical system that accurately models the experimental data. Finally, we interpret this continuum model from fundamental physics principles. Informed by …

Deep Transfer Learning-Based Bird Species Classification Using Mel Spectrogram Images, Mrinal Kanti Baowaly, Bisnu Chandra Sarkar, Md.Abul Ala Walid, Md. Martuza Ahamad, Bikash Chandra Singh, Eduardo Silva Alvarado, Imran Ashraf, Md. Abdus Samad

School of Cybersecurity Faculty Publications

The classification of bird species is of significant importance in the field of ornithology, as it plays an important role in assessing and monitoring environmental dynamics, including habitat modifications, migratory behaviors, levels of pollution, and disease occurrences. Traditional methods of bird classification, such as visual identification, were time-intensive and required a high level of expertise. However, audio-based bird species classification is a promising approach that can be used to automate bird species identification. This study aims to establish an audio-based bird species classification system for 264 Eastern African bird species employing modified deep transfer learning. In particular, the pre-trained EfficientNet …

Effect Of Alkaline Water In Controlling Oral Ph, Duc M. Nguyen

Dental Hygiene ETDs

This study was motivated by the widespread prevalence of dental caries, acknowledged as a global concern and often deemed a pandemic, coupled with the realization of limitations in existing caries prevention methods. The surge in the popularity of alkaline water for daily use, recognized for its health benefits, prompted an exploration of its potential role in averting dental caries. The central hypothesis, focusing on the remineralization benefits of alkaline water as a preventive method for dental caries, formed the basis of investigation. Structured with two phases and five steps, the study aimed to evaluate the impact of alkaline water on …

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2024, Michael Haederle, Claire Hannon, Nicole San Roman, Jett Loe, Sara Mota, Sarah Head

Research Annual Reports

Annual research report from the University of New Mexico Health Sciences Center.

Enhancement Of Antitumor Effects Of Berberine Chloride With A Copper(Ii) Complex Against Human Triple Negative Breast Cancer: In Vitro Studies, Duaa R. Alajroush, Brittney F. Anderson, Janae A. Bruce, Christian I. Lartey, Dazonte A. Mathurin, Sean T. Washington, Tanaya S. Washington, Sidy Diawara, Sakariyau A. Waheed, Kaylin L. Thomas, Stephen J. Beebe, Alvin A. Holder

Chemistry & Biochemistry Faculty Publications

In this study, the copper(II) complex [Cu(chromoneTSC)Cl₂]•0.5H₂O•0.0625C₂H₅OH (where chromoneTSC = (E)-N-Ethyl-2-((4-oxo-4H-chromen-3-yl)methylene)-hydrazinecarbothioamide) was synthesized and characterized; then used to carry out in vitro studies in combination with berberine chloride (BBC). The ligand and complex were characterized by elemental analysis, FTIR and NMR (¹H and ¹³C) spectroscopy, and conductivity measurements. The cytotoxic effect was analyzed by using the CCK-8 viability assay in cancer MDA-MB-231 VIM RFP and non-cancer MCF-10A cell lines. The IC₅₀ values for the complex and BBC were 21.2 ± 1.6 and 48.3 ± 2.4 μM, respectively at 24 h incubation, while the IC₅₀ value of the combination treatment …

The Impact Of Iron Supplementation On The Preterm Neonatal Gut Microbiome: A Pilot Study, Matthew Van Ormer, Maranda Thompson, Melissa Thoene, Jean-Jack Riethoven, Sathish Kumar Natarajan, Corrine K. Hanson, Ann Anderson-Berry

Journal Articles: Pediatrics

OBJECTIVE: The gastrointestinal microbiome in preterm infants exhibits significant influence on optimal outcomes-with dysbiosis shown to substantially increase the risk of the life-threatening necrotizing enterocolitis. Iron is a vital nutrient especially during the perinatal window of rapid hemoglobin production, tissue growth, and foundational neurodevelopment. However, excess colonic iron exhibits potent oxidation capacity and alters the gut microbiome-potentially facilitating the proliferation of pathological bacterial strains. Breastfed preterm infants routinely receive iron supplementation starting 14 days after delivery and are highly vulnerable to morbidities associated with gastrointestinal dysbiosis. Therefore, we set out to determine if routine iron supplementation alters the preterm gut …

The Intersection Of Special Education And Family Law: Thoughts For Family Law Attorneys In Divorce And Custody Cases, Richard D. Marsico

Articles & Chapters

The Individuals with Disabilities Education Act (IDEA) requires participating states to provide a free appropriate public education (FAPE) to children with disabilities. The IDEA gives parents of children with disabilities significant rights and major responsibilities in developing and maintaining their child’s education. Getting the most out of the IDEA for their children requires parents to commit substantial time and financial resources that are difficult to provide in the best circumstances. When parents are having marital difficulties, separated, undergoing a divorce, or negotiating child custody, these difficulties can be exacerbated as parents navigate the intersection of the federal IDEA and state …

Sound Marks, Deborah R. Gerhardt, Jon J. Lee

Faculty Publications

A lion roars just before a film rolls. A doughboy giggles. A giant green man laughs a hearty, "Ho, Ho, Ho." These iconic sounds are all federally registered as trademarks. They identify specific brands and distinguish their products and services from the competition. Human brains treat sounds like these as categorization tools and cognitive shortcuts—ideal trademark symbols. But what about the sounds your favorite toys or electronic devices make? Or those made by a fictional character in the latest blockbuster?

This Article tackles these issues and others. We push back against the widely-held belief that all unconventional trademarks—product designs, colors, …

Legal Gender Recognition In Nepal And Comparative Context, Holning S. Lau, Mara Malagodi

Faculty Publications

The Supreme Court of Nepal was a groundbreaker when it ruled in Pant v. Nepal (2007) that people have the right to change their gender on identity documents based on “self-feelings” and “self-determination” rather than medical or other criteria; at the time, no other national apex court or government had so clearly prioritized self-determination for gender identity. Pant, however, centered “third gender” persons (neither male nor female), and now the Court is considering the case of a transgender woman, Ms. Kapali, who seeks to be identified as female on her documents and is challenging authorities that rejected her requests. …

Breathing Nietzsche’S Atmospheres, Gary Shapiro

Philosophy Faculty Publications

This essay contextualizes the themes of breath and atmosphere in Nietzsche’s thinking, reading them in relation to certain contemporary crises and theories. Climate change and airborne pandemic challenge the tendency to position breath and atmosphere as life’s unthought background. Luce Irigaray’s phenomenological-feminist claim that Western philosophy has forgotten breath and James Nestor’s comprehensive investigation of medical, scientific, and disciplinary respiratory research programs provide contrasting frameworks for clarifying Nietzsche’s emphasis on breath as crucial to embodied human life. Atmospheric surround – taken in a spectrum of interrelated senses, meteorological to affective – is breath’s correlative. Nietzsche’s insistence on life’s irreducible atmospheric …

Applying The Principles Of Periodisation To Supplementary Training For Dance To Reduce Risks Of Overtraining, Sophie Molony

Theses : Honours

This research investigated the necessity of individualised training adaptations in dance, informed by physiological and psychological factors to nurture dancer physical and emotional wellbeing. Periodisation is a well known framework used, by professional athletes, as a way of dividing the training plan into smaller training cycles to develop skills and biomotor abilities to allow the athlete to perform optimally (physically, technically and mentally) and ensure peak performance at a specific time (Wyon & Allard, 2023). However, it is not yet well studied and implemented in dance (Wyon, 2010). Preparing the dancer with a periodisation model could potentially assist in supporting …

Enhancing Xml-Based Compiler Construction With Large Language Models: A Novel Approach, Idrees A. Zahid, Shahad Sabbar Joudar

Mesopotamian Journal of Big Data

Considering the prevailing rule of Large Language Models (LLMs) applications and the benefits of XML in a compiler context. This manuscript explores the synergistic integration of Large Language Models with XML-based compiler tools and advanced computing technologies. Marking a significant stride toward redefining compiler construction and data representation paradigms. As computing power and internet proliferation advance, XML emerges as a pivotal technology for representing, exchanging, and transforming documents and data. This study builds on the foundational work of Chomsky's Context-Free Grammar (CFG). Recognized for their critical role in compiler construction, to address and mitigate the speed penalties associated with traditional …

Mlp And Rbf Algorithms In Finance: Predicting And Classifying Stock Prices Amidst Economic Policy Uncertainty, Bushra Ali, Khder Alakkari, Mostafa Abotaleb, Maad M. Mijwil, Klodian Dhoska

Mesopotamian Journal of Big Data

In the realm of stock market prediction and classification, the use of machine learning algorithms has gained significant attention. In this study, we explore the application of Multilayer Perceptron (MLP) and Radial Basis Function (RBF) algorithms in predicting and classifying stock prices, specifically amidst economic policy uncertainty. Stock market fluctuations are greatly influenced by economic policies implemented by governments and central banks. These policies can create uncertainty and volatility, which in turn makes accurate predictions and classifications of stock prices more challenging. By leveraging MLP and RBF algorithms, we aim to develop models that can effectively navigate these uncertainties and …

Generalized Time Domain Prediction Model For Motor Imagery-Based Wheelchair Movement Control, Z. T. Al-Qaysi, M. S. Suzani, Nazre Bin Abdul Rashid, Reem D. Ismail, M. A. Ahmed, Rasha A. Aljanabi, Veronica Gil-Costa

Mesopotamian Journal of Big Data

Brain-computer interface (BCI-MI)-based wheelchair control is, in principle, an appropriate method for completely paralyzed people with a healthy brain. In a BCI-based wheelchair control system, pattern recognition in terms of preprocessing, feature extraction, and classification plays a significant role in avoiding recognition errors, which can lead to the initiation of the wrong command that will put the user in unsafe condition. Therefore, this research's goal is to create a time-domain generic pattern recognition model (GPRM) of two-class EEG-MI signals for use in a wheelchair control system. This GPRM has the advantage of having a model that is applicable to unknown …

Harnessing The Potential Of Artificial Intelligence In Managing Viral Hepatitis, Guma Ali, Maad M. Mijwil, Ioannis Adamopoulos, Bosco Apparatus Buruga, Murat Gök, Malik Sallam

Mesopotamian Journal of Big Data

Viral hepatitis continues to be a serious global health concern, impacting millions of people, putting a strain on healthcare systems across the world, and causing significant morbidity and mortality. Traditional diagnostic, prognostic, and therapeutic procedures to address viral hepatitis are successful but have limits in accuracy, speed, and accessibility. Artificial intelligence (AI) advancement provides substantial opportunities to overcome these challenges. This study investigates the role of AI in revolutionizing viral hepatitis care, from early detection to therapy optimization and epidemiological surveillance. A comprehensive literature review was conducted using predefined keywords in the Nature, PLOS ONE, PubMed, Frontiers, Wiley Online Library, …

Hybrid Spotted Hyena Based Load Balancing Algorithm (Hshlb), Raed A. Hasan, Mustafa M. Akawee, Enas F. Aziz, Omar A. Hammood, Aws Saad Showket, Husniyah Jasim, Mohammed A. Alkhafaji, Omar K. Ahmed, Khalil Yasin

Mesopotamian Journal of Big Data

In this paper, we delve into the core of our proposed dynamic load balancing mechanism, the Hybrid Spotted Hyena based Load Balancing algorithm (HSHLB). We begin by presenting a comprehensive overview of the Spotted Hyena Optimization Algorithm (SHOA) and the fundamental behaviors it encompasses, namely migration and attacking. We then introduce the Load Balancing Algorithm (LB) and outline its principles, emphasizing its distinct characteristics. Recognizing the strengths and weaknesses of both SHOA and LB, we embark on a journey to hybridize these two optimization techniques, resulting in the potent HSHLB. We elucidate the intricate process of combining these algorithms, elucidating …

A Poison Like No Other: How Microplastics Corrupted Our Planet And Our Bodies By Matt Simon, Heath Skroch

Natural Resources Journal

No abstract provided.

Clinical Study Of Combined Arthroscopic Drilling And Platelet Rich Plasma Injection In Knee Osteochondral Lesions In Middle-Aged Patients, Mohamed Salah Labib Mohamed, Mohamed Abd Elmoneam Gafar

Journal of Medicine in Scientific Research

Background: Osteochondral lesions commonly occur in the knee joints and causes detrimental effects on the quality of life. Arthroscopic drilling is the treatment option for mild to moderate lesions. However, it is debatable whether regenerated cartilage from arthroscopic drilling surgery is durable. It is speculated that induction of chondrocyte differentiation from subchondral mesenchymal stem cells is facilitated by platelet-rich plasma (PRP), which is a rich source of diverse growth factors.

Aim of work: To evaluate the procedures of combined arthroscopic drilling and PRP injection intra-articularly for mild to moderate knee osteochondral lesions management.

Patients and Methods: This randomized prospective study …

Female Athletes Explicitly Gesture In Emotional Situations, Y. Adams, M. Augenstein, P. Furley, A. Krieg, P. Born, I. Helmich

Exercise and Sport Studies: Faculty Publications

Introduction: Both appraisal emotion approaches and self-regulation theory emphasize that appraising an event as conducive or detrimental to one’s current goals may trigger an affective response that can be observed nonverbally. Because there may be a female advantage in the inhibition and self-regulation of emotions, we hypothesized that female but not male athletes regulate emotions during sports through explicit nonverbal behaviors. Methods: All nonverbal hand movement behavior of right-handed female and male tennis athletes was recorded during competitive matches. All immediate nonverbal expressions after point losses and wins were coded by two independent blind raters applying the NEUROpsychological GESture (NEUROGES®) …

Human Rights, Poverty, And Care Of Girls And Women With The Prospect Of A Baby, Mccauliff, Catherine M.A.

Santa Clara Law Review

Human rights provide the lens used here to examine the treatment of women and girls at a time in their lives when they deserve the utmost respect, understanding and assistance, when they are early in a pregnancy, wanted or not, the result of violence or not, or a miscarriage of a wanted child. We live in a society where “[e]ssentially, people will have children if they feel they have job security, a stable economy, and feel supported in starting a family.” Some countries and cities provide assistance to a mother upon the birth of a child in the form of …

Introducing Comprehensive Sexuality Education And Hiv Prevention And Treatment Methods Through Pop-Up Clinics To Secondary School Girls In Kwazulu-Natal, South Africa, Eliza I. Tobin, Joaquin Carlos Pinga, Caitlyn Stanya

Capstone Showcase

Human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system leading to people living with HIV (PLHIV) immunodeficient and more susceptible to other infections or diseases (UNAIDS, 2023b). This can lead to acquired immunodeficiency syndrome (AIDS) within 8-10 years of infection (UNAIDS, 2023b). HIV does not always present symptoms, making it hard for people to identify their HIV status without proper screening. The lack of awareness around a person’s status has led HIV to spread worldwide. In addition to the worldwide spread of HIV, there is no cure for the disease, however, antiretroviral therapy (ART) is mainly used …

Power Dynamics And Oppression: Analyzing Structural Control In Suzanne Collins’S The Hunger Games, Hannah Micciolo

Capstone Showcase

The Hunger Games is a popular novel universe that describes a totalitarian dictatorship through the lens of the oppressed. Through the book, the viewer is given insight into how Panem operates the way it does even though the majority of its citizens are oppressed by the minority in a much more obvious manner. However, within modern society, the tactics used by the oppressors are much more ambiguous and distorted. This essay will explore the structures put in place by the Capitol in tandem with modern examples to mirror each other and increase awareness of the the tactics governments use both …

Developing Best Practices For Successful University Fundraising Events, Ravyn Ladenburger

MPA/MPP/MPFM Capstone Projects

This research study addresses the crucial role of fundraising in sustaining universities in the United States, particularly public institutions facing funding challenges. For this paper, fundraising refers to the seeking of financial support from individuals to support initiatives at a nonprofit entity, such as a public university. It identifies a gap in research and professionalization within higher education philanthropy, emphasizing the need for standardized training and empirical research. The focus is on studying the effectiveness of fundraising events, especially in public universities like the University of Kentucky, amidst declining government support and rising operational costs. The research problem to be …

The Fairness Model Of Legal Institutions, James M. Donovan

Law Faculty Books and Chapters

If any group is to endure over time, individual frustrations, while inevitable, must be usually experienced as acceptable, or at least tolerable. Failing that, little would prevent the losers in these conflicts from leaving or revolting, which would be cumulatively debilitating to the group. As opposed to holding law’s job to impose order and police infringers, the second approach suggests that finding the balance between group and individual desires is the ‘major difficulty of all law—the problem of really getting a fresh start in relations between litigants after disposition of a trouble-case. This is the problem not only of keeping …

Copper Resistance In Staphylococcus Epidermidis: Role Of The Multicopper Oxidase Gene, Caroline Sundal

Scripps Senior Theses

The ongoing struggle against antibiotic resistance and the lack of new antibiotic discoveries being made is a threat to global health. Alternate forms of antibacterial treatment are an important area of research to increase the treatment efficacy of clinical antimicrobial applications. In this research paper, we examine the model organism Staphylcoccus epidermidis, one of the leading causes of nosocomial infection. S. epidermidis normally resides on skin and mucus, however, can become an opportunistic pathogen if it invades the body, entering the bloodstream via the insertion of medical and prosthetic devices. Copper was a traditional therapy in ancient Egypt used for …