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Articles 8701 - 8730 of 818072
Full-Text Articles in Entire DC Network
Functional Characterization Of Stmtpsl Terpene Synthase-Like Genes And Their Role In Pathogen Resistance In Selaginella Tamariscina, Zhijie He, Bo Bi
Functional Characterization Of Stmtpsl Terpene Synthase-Like Genes And Their Role In Pathogen Resistance In Selaginella Tamariscina, Zhijie He, Bo Bi
Turkish Journal of Agriculture and Forestry
The biological activity and function of microbial terpene synthase-like genes from Selaginella tamariscina (StMTPSL) were investigated using molecular and biochemical approaches. After isolating and amplifying StMTPSL genes (StMTPSL1-StMTPSL6), both native and site-directed mutant forms were expressed in tobacco via Agrobacterium-mediated transformation. The resulting transgenic plants had increased expression of StMTPSL genes, enhanced monoterpene production (as confirmed by GC-MS), and significantly improved resistance to Pseudomonas syringae infection compared to nontransgenic controls. These results show that StMTPSL genes are functionally active in plants and contribute to pathogen resistance through elevated terpene biosynthesis. This study provides new insights into the role of MTPSL …
Effect Of Some Organic Fertilizers On Yield And Quality Of Olive Oil In Semiarid Conditions, İshak Bayyi̇ği̇t, Ebru Sakar
Effect Of Some Organic Fertilizers On Yield And Quality Of Olive Oil In Semiarid Conditions, İshak Bayyi̇ği̇t, Ebru Sakar
Turkish Journal of Agriculture and Forestry
This two-year field experiment evaluated the effects of different organic fertilizers on olive oil quality of the Gemlik cultivar grown under semiarid conditions in Mardin, Türkiye. Treatments of olive pomace (P1: 4, P2: 8, P3: 12 kg tree⁻¹), leonardite (L1: 1.5, L2: 3.0, L3: 4.5 kg tree⁻¹), and vermicompost (SG1: 3, SG2: 6, SG3: 9 kg tree⁻¹) were applied in a randomized complete block design with three replicates. Oils were analyzed for free acidity (FA), peroxide value, and phenolic profile using high-pressure liquid chromatography. FA ranged from 0.27% to 0.42% (as oleic acid), remaining well below the International Olive Council …
Analysis Of Agricultural Remote Sensing Data Driven By Artificial Intelligence On Crop Growth Patterns And Economic Benefits Of Grain, Yang Wang
Turkish Journal of Agriculture and Forestry
To address the shortcomings of conventional agricultural statistical and monitoring methods on a regional scale, this paper proposes the use of artificial intelligence-driven remote sensing data for analysing crop growth patterns and the economic benefits of grain. Winter wheat data from three stations in a single province from 2011 to 2020 was used, with the leaf area index (LAI) used as the key crop growth indicator value. The simulated annealing algorithm was used to assimilate the LAI and remote sensing leaf area index (MODIS-LAI), simulated by the World Food Study (WOFOST) simulation model, to carry out simulation analysis of winter …
Spectrophotometric Detection Of Food Additives And Pesticides By Magnetite Cross-Linked Tyrosinase Aggregates (Mcltas), İlker Polatoğlu
Spectrophotometric Detection Of Food Additives And Pesticides By Magnetite Cross-Linked Tyrosinase Aggregates (Mcltas), İlker Polatoğlu
Turkish Journal of Agriculture and Forestry
In this study, tyrosinase enzyme was cross-linked with glutaraldehyde to form aggregates on the surface of activated magnetite nanoparticles, without the need for a separate support matrix. For the first time, this novel aggregate was employed for the spectroscopic detection of ascorbic acid (AA) and diazinon, as model food additives and pesticides, respectively. This technique, developed as an alternative to optical sensors, not only eliminates their drawbacks but also facilitates the recovery of cross-linked enzyme aggregates (CLEA) from the reaction medium using the incorporated magnetite nanoparticles. A spectrophotometric technique was used to measure the enzyme activity of the aggregates to …
Nitrogen Transport Patterns And Vegetation Community Optimization In Urban Green Space Soils Using Multifactor Coupling Analysis, Shujian Yang, Baoxi Yu, Zheng He, Baochang Liu, Chang Liu
Nitrogen Transport Patterns And Vegetation Community Optimization In Urban Green Space Soils Using Multifactor Coupling Analysis, Shujian Yang, Baoxi Yu, Zheng He, Baochang Liu, Chang Liu
Turkish Journal of Agriculture and Forestry
As vital components of urban ecosystems, urban green spaces directly affect soil fertility and plant growth through nitrogen transport dynamics. This study addresses the existing methodological gaps in understanding nitrogen cycling within urban green spaces, particularly the unclear interaction mechanisms between vegetation structure and soil physicochemical characteristics. The study was conducted in the Green Expo Park located in Nanjing, China. Using a stratified sampling approach, physicochemical indicators of soil layers were measured and combined with community parameters—including leaf area index, vegetation coverage, and plant density—to identify key drivers through correlation and multiple regression analyses. The regulatory mechanisms of soil physicochemical …
Long-Term Tillage And Straw Returning Practices Enhance Soil Humus Composition, Carbon Sequestration, And Ecological–Economic Benefits, Kai Wang
Turkish Journal of Agriculture and Forestry
While straw return is widely promoted, its specific effects on soil humus composition, structure, and ecological functions are not fully understood. This study investigates the long-term impacts of different straw types and farming practices on humus composition, carbon sequestration, and ecological–economic benefits. In Hunan Province’s paddy fields, six soils with 5–30-year farming histories were selected. Treatments included a blank control, corn straw return, and rice straw return, each replicated three times. Humus structure was analyzed via infrared spectroscopy, component contents were determined by alkali extraction, and a carbon footprint model assessed emissions. Ecological economic analysis integrated soil carbon pool dynamics, …
Vanadium’S Journey From Essential Trace Metal To Emerging Environmental Pollutant In The Anthropocene Era, Tanu Arora, Nivedita Agnihotri, Mohammad Azam
Vanadium’S Journey From Essential Trace Metal To Emerging Environmental Pollutant In The Anthropocene Era, Tanu Arora, Nivedita Agnihotri, Mohammad Azam
Turkish Journal of Chemistry
Vanadium, previously considered a minor trace element, is gaining global environmental attention due to its expanding applications in metallurgy, energy storage, catalysis, and agriculture. With this rise in its industrial and technological uses, however, anthropogenic emissions of vanadium into the atmosphere, soils, and water bodies have also escalated. Unlike many heavy metals, vanadium exhibits complex redox behavior, primarily existing as V(IV) and V(V) species, which significantly impacts its environmental mobility, bioavailability, and toxicity. Vanadium exhibits complex behavior that necessitates an integrated research approach to better understand its various roles in scientific fields. This review summarizes the current knowledge on vanadium’s …
Computational And Experimental Analysis Of Oleanolic Acid As An Allosteric Activator Of Sirt1, Emrah Sariyer, Eda Dokumacioğlu, Hati̇ce İskender
Computational And Experimental Analysis Of Oleanolic Acid As An Allosteric Activator Of Sirt1, Emrah Sariyer, Eda Dokumacioğlu, Hati̇ce İskender
Turkish Journal of Chemistry
Sirtuin 1 (SIRT1) is a member of the sirtuin protein family and the biological effects of SIRT1 encompass various areas such as the ageing process, metabolism regulation, and cellular stress response. SIRT1 activators are compounds that enhance the activity of SIRT1 enzyme. These activators can be natural or synthetic compounds and have the potential to provide health benefits by augmenting the biological effects of SIRT1. Oleanolic acid (OA) is a triterpenoid compound that has antiinflammatory, antioxidant, and glucose and lipid metabolism-regulating properties naturally found in many plants. The aim of the present study was to investigate the effect of OA …
Holding The Line: The Existential Threat To Dei Language And Values, Terrance Fitzsimmons, Larry Martinez, Jennifer Bishop, Darryl Rice, Florence Villesèche
Holding The Line: The Existential Threat To Dei Language And Values, Terrance Fitzsimmons, Larry Martinez, Jennifer Bishop, Darryl Rice, Florence Villesèche
Psychology Faculty Publications and Presentations
Purpose – This article critically analyses and critiques the operationalisation of the Trump administration’s anti- DEI policies on Diversity, Equity and Inclusion (DEI) initiatives in the United States of America and beyond. It specifically examines the attempt to silence DEI scholarship and practice, assessing the broader implications for social justice and global progress towards equity. The article also positions these attacks as an existential threat to DEI scholarship, scholars and practitioners, with the potential to reverse progress made since the adoption of the Universal Declaration of Human Rights in 1948. The article serves as a call to action, urging the …
Relationships Between Adolescents With Substance Use Disorders, Their Guardians, And Expressive Arts Therapy: A Literature Review, Sarah K. Unkefer
Relationships Between Adolescents With Substance Use Disorders, Their Guardians, And Expressive Arts Therapy: A Literature Review, Sarah K. Unkefer
Expressive Therapies Theses
This literature review collects the comprehensive, current research around effective treatment of adolescents with substance use disorder (SUD) and explores ways to provide psychoeducation for the adolescent and their guardians to foster healthy relationships and open communication. This author explores the ways that expressive arts therapy influences treatment and long-term recovery of adolescents with substance use disorders (SUDs) by addressing familial communication and internalized stigma. Previous studies have shown that the current primary reaction from guardians is forcing abstinence, which often damages the adolescent-guardian relationship. Since this is one of the most important relationships in an adolescent’s projected recovery journey, …
The Right Of Nature: Lessons From Panama For Mangrove Protection In Miami, Jayson Fry
The Right Of Nature: Lessons From Panama For Mangrove Protection In Miami, Jayson Fry
University of Miami Inter-American Law Review
Mangrove ecosystems are indispensable to climate resilience, yet traditional environmental governance has repeatedly failed to prevent their decline. This Note employs a comparative framework to examine Panama and Miami, two rapidly developing coastal regions facing parallel pressures of urbanization and sea-level rise, to demonstrate that mangrove loss persists not because law is absent, but because existing frameworks structurally authorize regulated degradation. Panama’s 2022 Rights of Nature Law, which grants ecosystems legal personhood and enforceable rights, represents a departure from anthropocentric environmental regulation. Its early judicial application in the Cobré Panamá mine case shows how rights-based protections can override extractive economic …
Analyzing Proposed Unmanned Aerial System Regulations And Their Impact On Manned Aircraft Operations, Kordell Irish
Analyzing Proposed Unmanned Aerial System Regulations And Their Impact On Manned Aircraft Operations, Kordell Irish
Honors Theses
The purpose of the thesis is to investigate the current state of the proposed Part 108 regulations and to find possible solutions to the problems faced by Part 108 implementation, with a focus on the interactions between manned and unmanned aircraft. The thesis covers upcoming changes to federal aviation regulations by the Federal Aviation Administration (FAA) regarding unmanned aircraft systems and their integration into the national airspace system. Currently, most unmanned aircraft systems (UAS) are regulated under Part 107 of the federal aviation regulation. A brief literature review will provide a background and timeline in the lead-up to the Part …
Erk Builds A Population Of Short-Lived Nascent Adhesions That Produce Persistent Edge Protrusion And Cell Migration, Andrew P. Shepherd, Keith R. Carney, Majid Rostami, Jakaria Shawon, Andrew Elliott, Shiela C. Samson, Sangyoon J. Han, Michelle C. Mendoza
Erk Builds A Population Of Short-Lived Nascent Adhesions That Produce Persistent Edge Protrusion And Cell Migration, Andrew P. Shepherd, Keith R. Carney, Majid Rostami, Jakaria Shawon, Andrew Elliott, Shiela C. Samson, Sangyoon J. Han, Michelle C. Mendoza
Michigan Tech Publications
Cell migration is realized through the fast and persistent protrusion of a leading edge in the direction of movement. The actin and adhesion structures that build edge protrusions are integrated such that pro-migration signaling pathways must control both assemblies to induce protrusion. Understanding the contribution of adhesion regulation has been complicated by the inability to selectively assay the nascent adhesions that promote edge protrusion. Here, we dissect how the core RAS → RAF → MEK → ERK pathway’s control of nascent adhesions contributes to edge protrusion and cell migration by targeting an ERK FRET biosensor to adhesions and quantifying ERK’s …
Mitigation Of Salinity Stress In Carnation Plants Through Zinc Oxide Nanoparticles: Growth, Physiological, And Biochemical Responses, Adel A. Rezk, Ishtiaq Ahmad, Maryam, Muhammad Saleem, Othman Al-Dossary, Hossam S. El-Beltagi, Mohammed Aldaej, Bader Y. Alsubaie, Hati̇ce Gülen, Tarek Shalaby, Riaz Ahmad
Mitigation Of Salinity Stress In Carnation Plants Through Zinc Oxide Nanoparticles: Growth, Physiological, And Biochemical Responses, Adel A. Rezk, Ishtiaq Ahmad, Maryam, Muhammad Saleem, Othman Al-Dossary, Hossam S. El-Beltagi, Mohammed Aldaej, Bader Y. Alsubaie, Hati̇ce Gülen, Tarek Shalaby, Riaz Ahmad
Turkish Journal of Agriculture and Forestry
Carnation (Dianthus caryophyllus L.) growth and floral yield are severely reduced when grown in soils with excessive salinity. Mitigation of adverse effects from salinity-induced stress is necessary for sustainable carnation cultivation. Although various approaches have been developed, the use of zinc oxide nanoparticles (ZnO-NPs) to ameliorate these effects remains scarcely explored. The current study explored the potential of ZnO-NPs to alleviate salinity-induced stress by examining their effects on morphophysiological and biochemical traits. A controlled pot experiment was conducted using a factorial design with three concentrations of sodium chloride (0, 50, and 100 mM) and three of ZnO-NPs (0, 50, and …
Silicon-Mediated Enhancement Of Wheat Tolerance To Drought Stress: A Comparative Study Of Antioxidant Activity, Photosynthesis, Secondary Metabolites, And Yield, Abida Kausar, Rida Yasmeen, Shahid Iqbal, Muhammad Bilal Hafeez, Asif Mukhtiar, Sadia Azeem, Ali Raza, Samreen Nazeer, Muhammad Zubair Akram, Muhammad Kamran, Fahd Rasul, Noreen Zahra
Silicon-Mediated Enhancement Of Wheat Tolerance To Drought Stress: A Comparative Study Of Antioxidant Activity, Photosynthesis, Secondary Metabolites, And Yield, Abida Kausar, Rida Yasmeen, Shahid Iqbal, Muhammad Bilal Hafeez, Asif Mukhtiar, Sadia Azeem, Ali Raza, Samreen Nazeer, Muhammad Zubair Akram, Muhammad Kamran, Fahd Rasul, Noreen Zahra
Turkish Journal of Agriculture and Forestry
Drought stress (DS) is a major constraint on optimal plant growth and yield. Agricultural researchers have been actively exploring fertilizers that can enhance crop production under DS conditions. Silicon (Si) application has emerged as a promising strategy for managing DS in various crops. This study investigated the potential of Si soil drenching to mitigate the adverse effects of varying levels of DS (at 100%, 70%, and 40% field capacity) in wheat. Two varieties (Ujala-2016 and FSD-2008) were used to evaluate the influence of Si (2.5 mM) on antioxidant activity, oxidative burst, secondary metabolites, growth, and yield. The results indicated that …
Ultrasound-Assisted Enzymatic Extraction Improves The Antiinflammatory Activity Of Red Dragon Fruit Peel Pectin, Bao Le, Seung Hwan Yang, Hoang Dang Khoa Ta
Ultrasound-Assisted Enzymatic Extraction Improves The Antiinflammatory Activity Of Red Dragon Fruit Peel Pectin, Bao Le, Seung Hwan Yang, Hoang Dang Khoa Ta
Turkish Journal of Biology
Background/aim: Inflammatory bowel disease is a chronic inflammatory disorder characterized by excessive immune activation, primarily mediated by nitric oxide and proinflammatory cytokines. This condition encompasses ulcerative colitis and Crohn’s disease, both of which significantly impair patients’ quality of life and pose persistent challenges in clinical management. Pectin, a complex carbohydrate found in plant cell walls, has shown promise in reducing inflammation. Materials and methods: In this study, pectin was extracted from red dragon fruit peel using two methods: ultrasound-assisted extraction and ultrasound-assisted enzymatic extraction. The structural characteristics and antiinflammatory effects of the extracted pectin were evaluated in lipopolysaccharide-stimulated RAW 264.7 …
Single-Walled Carbon Nanotube-Mediated Plasmid Dna Delivery In The Model Monocot Brachypodium Distachyon, Kaya İşleyen Bi̇lge, Bahar Soğutmaz Özdemi̇r
Single-Walled Carbon Nanotube-Mediated Plasmid Dna Delivery In The Model Monocot Brachypodium Distachyon, Kaya İşleyen Bi̇lge, Bahar Soğutmaz Özdemi̇r
Turkish Journal of Biology
Background/aim: Plant genetic engineering is a valuable approach for improving stress tolerance, crop productivity, and quality traits. However, its progress is limited by the drawbacks of traditional transformation methods. Commonly used techniques, such as Agrobacterium-mediated transformation and biolistics, are restricted by genotype dependency, lengthy tissue culture steps, and low efficiency, particularly in monocot species. Therefore, the development of alternative gene delivery strategies remains an ongoing research focus in plant biotechnology. Nanoparticle-based delivery systems have recently gained attention due to their physiochemical properties, biocompatibility, and potential for alternative gene delivery approaches in plant systems.Materials and methods: We investigated the use of …
Combinatorial Effect Of Epirubicin And 5-Fluorouracil In The Treatment Of Temozolomide-Resistant Glioblastoma Cells, Mehrsa Bayat, Muhli̇s Akman, Türker Kiliç, Ti̇muçi̇n Avşar
Combinatorial Effect Of Epirubicin And 5-Fluorouracil In The Treatment Of Temozolomide-Resistant Glioblastoma Cells, Mehrsa Bayat, Muhli̇s Akman, Türker Kiliç, Ti̇muçi̇n Avşar
Turkish Journal of Biology
Background: Glioblastoma (GBM) is a highly aggressive form of brain tumor characterized by rapid proliferation and invasiveness. It is associated with a poor prognosis due to acquired resistance to temozolomide (TMZ). In this study, we investigated whether a combination of epirubicin, 5-fluorouracil (5-FU), and TMZ could improve TMZ sensitivity in resistant GBM cells and help overcome resistance.Materials and methods: TMZ resistance was established in the U87MG cell line. The MTT assay was used to measure cell viability. Reactive oxygen species (ROS) and apoptosis were measured using flow cytometry. RNA-seq was used to evaluate genomic changes based on treatment with drugs …
Modulating Microtubule Stability Via Α-Tubulin Acetylation Partially Restores Golgi Fragmentation In Spinal Muscular Atrophy, Peli̇n Zobaroğlu Özer, Memet Gözüböyük, Özge Çeti̇n, Niko Hensel, Güzi̇n Emecen, Adam Malik, Melissa Bowerman, Peter Claus, Hayat Erdem Yurter, Gamze Bora Akoğlu
Modulating Microtubule Stability Via Α-Tubulin Acetylation Partially Restores Golgi Fragmentation In Spinal Muscular Atrophy, Peli̇n Zobaroğlu Özer, Memet Gözüböyük, Özge Çeti̇n, Niko Hensel, Güzi̇n Emecen, Adam Malik, Melissa Bowerman, Peter Claus, Hayat Erdem Yurter, Gamze Bora Akoğlu
Turkish Journal of Biology
Background/aim: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by the loss of survival of motor neuron (SMN) protein. SMN deficiency leads to perturbations of the cytoskeleton, including microtubules, which are mainly involved in motilityrelated cellular processes. However, the molecular mechanisms of microtubule dysregulation in SMA remain elusive. Alpha (α)-tubulin is a structural component of microtubules, and its posttranslational modifications affect microtubule dynamics. Here, we aimed to investigate α-tubulin acetylation and related molecular mechanisms in SMA. Materials and methods: Two different SMA mouse models, the Drosophila melanogaster model and patient-derived fibroblasts, were used in the study. Western blot and …
Volume 104, Number 1 - Spring 2026, The Alembic
Volume 104, Number 1 - Spring 2026, The Alembic
The Alembic
Cover "The Stars are Screaming in the Field Outside my Apartment" by Hale Mueller
The Truth, Owen R. Kruger
Contributors’ Notes, The Alembic
2026 Undergraduate Research Symposium Program, Coastal Carolina University
2026 Undergraduate Research Symposium Program, Coastal Carolina University
Undergraduate Research Symposium Programs
17th Annual Undergraduate Research Symposium, April 21-22, 2026.
The 2026 CCU Undergraduate Research Symposium included 72 oral presentations, 127 poster presentations, and 22 team pitch presentations comprising 50 students who participated in the Wall College’s Chant’s Tank Pitch Competition.
Presentations at the Undergraduate Research Symposium were judged by almost 90 faculty and staff, and prizes were awarded in three categories: Best Oral Presentation, Best Poster Presentation, and Best Chant’s Tank Pitch Presentation. Here are the following award winners and their mentors in their respective categories:
Best Oral Presentation:
- 1st Place: Ryan Ryan Avallone, Applied Mathematics. Faculty Mentor: Bong Jeong (Management …
Increasing New Hampshire’S Winter Oyster Survival, Mark Wanner
Increasing New Hampshire’S Winter Oyster Survival, Mark Wanner
UNH Today Archive
No abstract provided.
Construction And Characterization Of Novel Mycobacterium Tuberculosis-Derived Triple And Quadruple Knockout Vaccines Against Tuberculosis, Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Shrikanth S. Gadad, Subramanian Dhandayuthapani
Construction And Characterization Of Novel Mycobacterium Tuberculosis-Derived Triple And Quadruple Knockout Vaccines Against Tuberculosis, Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Shrikanth S. Gadad, Subramanian Dhandayuthapani
School of Medicine Publications
Tuberculosis (TB) is a deadly disease that claims the lives of over a million people each year worldwide. The Bacille Calmette-Guérin vaccine has long been used to protect against TB, but it produces variable effects across different populations and fails to protect against adult pulmonary TB. Therefore, there is an urgent need for alternative vaccines that can offer better protection. We have developed a strategy for the rational deletion of virulence-related genes in Mycobacterium tuberculosis (Mtb) to create hyperattenuation that also enhances immunogenicity. Previously, we generated both single (∆fbpA) and double knockout (DKO) (∆fbpA-∆sapM) mutants of …
Integration Of Bayesian Networks And Neural Networks For High-Dimensional Data Analysis, Cooper Schmer
Integration Of Bayesian Networks And Neural Networks For High-Dimensional Data Analysis, Cooper Schmer
Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research
High-dimensional biomedical datasets, such as omics data, present significant challenges for predictive modeling due to noise, redundancy, and computational complexity. This thesis proposes a hybrid framework that integrates Bayesian Networks (BNs) and Artificial Neural Networks (NNs) to improve classification performance of such data sets while reducing input dimensionality. Central to this work is a novel feature selection method based on d-separation, a structural property of Bayesian networks that encodes conditional independence relationships.
The proposed approach introduces a count-based d-separation metric to quantify the relevance of variables to a target outcome, along with a thresholding scheme to balance feature selection robustness …
Sensitive Stripping Voltammetric Determination Of An Anthracene–Isatin Schiff Base In Biological Samples, Gökçe Öztürk, İrem Gökgöz, Emi̇ne Arslan, Eli̇f Şi̇şman, İnci̇ Seli̇n Doğan, Di̇lek Kul, Fatma Ağin
Sensitive Stripping Voltammetric Determination Of An Anthracene–Isatin Schiff Base In Biological Samples, Gökçe Öztürk, İrem Gökgöz, Emi̇ne Arslan, Eli̇f Şi̇şman, İnci̇ Seli̇n Doğan, Di̇lek Kul, Fatma Ağin
Turkish Journal of Chemistry
In the present study, the electrochemical behavior and quantitative determination of the Schiff base 3-[(anthracen-2-yl)imino]-5-nitro-1,3-dihydro-2H-indol-2-one (ANT) were investigated for the first time using voltammetric techniques at a glassy carbon electrode. The effects of solvent composition, pH, and scan rate on the redox behavior of ANT were systematically evaluated. The compound exhibited an irreversible oxidation process governed by adsorption-controlled kinetics. Quantitative analysis was conducted using differential pulse stripping voltammetry (AdS-DPV) and square-wave stripping voltammetry (AdS-SWV) under optimized conditions. Both methods exhibited linear responses over the concentration range of 0.2–8.0 μM, with limits of detection of 0.0366 μM and 0.0433 μM for …
Investigation Of The Enzyme-Inhibitory, Antibacterial, And Anticancer Properties Of Metal Phthalocyanines, Meryem Topal, Fevzi̇ Topal, Firat Yilmaz, Esra Bulut Atalay, Ümi̇t Muhammet Koçyi̇ği̇t, Emre Güzel
Investigation Of The Enzyme-Inhibitory, Antibacterial, And Anticancer Properties Of Metal Phthalocyanines, Meryem Topal, Fevzi̇ Topal, Firat Yilmaz, Esra Bulut Atalay, Ümi̇t Muhammet Koçyi̇ği̇t, Emre Güzel
Turkish Journal of Chemistry
In this study, the enzyme inhibitory, antibacterial, and anticancer activities of a phthalonitrile derivative and its metal phthalocyanines (Pcs; indium, zinc, copper, cobalt, and manganese; 1–6) were investigated. The cobalt and manganese Pcs were synthesized for the first time in this study. The inhibitory activities of the symmetric Pcs, which were expected to interact with acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) via their 4-(isopropylbenzyl)oxy substituents through host–guest interactions, were investigated. More selective inhibition of AChE than BChE was observed for these compounds. For AChE, CoPc was identified as the most potent inhibitor (IC50 = 14.81 nM), whereas for BChE, InPc was …
Templating Effect Of Neutral Dithiane Ligands On The Self-Assembly Of Cationic Au(I)-Phosphine Units, Farzane Osanlou, Abdollah Neshat, Mohammad Reza Yousefshahi, Vaclav Eigner, Michal Dusek, Shahram Seidi
Templating Effect Of Neutral Dithiane Ligands On The Self-Assembly Of Cationic Au(I)-Phosphine Units, Farzane Osanlou, Abdollah Neshat, Mohammad Reza Yousefshahi, Vaclav Eigner, Michal Dusek, Shahram Seidi
Turkish Journal of Chemistry
The interactions between the dinuclear Au(I) precursor (dppm)Au2Cl2 and neutral sulfur-containing dithianes (specifically 1,3- and 1,4-dithiane) were examined in the presence of NH₄PF₆. Although these sulfur-based ligands were initially employed to facilitate the formation of mixed phosphine/sulfur Au(I) complexes, single-crystal X-ray diffraction analysis revealed the unexpected generation of multinuclear Au(I) assemblies exclusively coordinated by phosphine ligands. When 1,3-dithiane was present, a trinuclear Au(I) complex was isolated, characterized by a central four-coordinate Au(I) center exhibiting a distorted see-saw geometry, flanked by two terminal Au(I) centers with T-shaped coordination environments. Importantly, the dithiane ligand did not coordinate directly to the gold centers …