Digital Commons Network^™

Kenyon Collegian - February 15, 2024

The Kenyon Collegian

No abstract provided.

Illinois State University Founding Celebration Program, February 15, 2024, Illinois State University

Founding Celebration Programs

Program for annual event celebrating the founding of Illinois State Normal University on February 18, 1857.

Editorial: Pharmacology Of Endocrine Related Gpcrs, Francesco De Pascali, Aylin Hanyaloglu, Frederic Jean-Alphonse, Francesco Potì, Eric Reiter

Department of Biochemistry and Molecular Biology Faculty Papers

No abstract provided.

Small Airways In Non-Cystic Fibrosis Bronchiectasis, John D Dickinson, Christopher M Evans, Burton F Dickey

Faculty, Staff and Student Publications

No abstract provided.

A Mutation In F-Actin Polymerization Factor Suppresses The Distal Arthrogryposis Type 5 Piezo2 Pathogenic Variant In Caenorhabditis Elegans, Xiaofei Bai, Harold E Smith, Luis O Romero, Briar Bell, Valeria Vásquez, Andy Golden

Faculty, Staff and Student Publications

The mechanosensitive PIEZO channel family has been linked to over 26 disorders and diseases. Although progress has been made in understanding these channels at the structural and functional levels, the underlying mechanisms of PIEZO-associated diseases remain elusive. In this study, we engineered four PIEZO-based disease models using CRISPR/Cas9 gene editing. We performed an unbiased chemical mutagen-based genetic suppressor screen to identify putative suppressors of a conserved gain-of-function variant pezo-1[R2405P] that in human PIEZO2 causes distal arthrogryposis type 5 (DA5; p. R2718P). Electrophysiological analyses indicate that pezo-1(R2405P) is a gain-of-function allele. Using genomic mapping and whole-genome sequencing approaches, we identified a …

February 15, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Can Mirna Be The Missing Link Between Parkinson’S Disease And Pesticides?, Fatma Gobba

Theses and Dissertations

Parkinson’s disease (PD) is a common neurodegenerative condition that leads to significant morbidity and a decline in the quality of life. It develops as a consequence of the loss of dopaminergic neurons in the substantia nigra pars compacta. Nevertheless, the development of PD is influenced by environmental factors, and the intricate nature of these relationships is further complicated by a multitude of factors, including the genetic backgrounds that are specific to populations and variations in environmental exposures, such as pesticides. Pesticides, consisting of a diverse family of chemicals commonly used in both agricultural and household settings to protect crops against …

The Role Of Endowments In Achieving The Goals Of Security And Freedom, Eiman Alhashmi

All Works

This research explores the expansive concept of freedom within Islamic endowments, or Waqf, emphasizing liberation from societal constraints like poverty and disability. It asserts that moral constraints restrict human freedom, necessitating a call to Allah for liberation. Historical examples, such as Al-Azhar University, highlight endowments' pivotal role in fostering independence from state pressures, particularly in the realms of thought and education. Endowments are depicted as vital in sustaining and liberating society, offering financial autonomy to scholars and educational institutions. The text also delves into the economic impacts of endowments, detailing their role in employment, income redistribution, and fostering various industries. …

Swimmer’S Itch Control: Timely Waterfowl Brood Relocation Significantly Reduces An Avian Schistosome Population And Human Cases On Recreational Lakes., Randall Dejong, Harvey D. Blankespoor, Curtis L. Blankespoor

University Faculty Publications and Creative Works

Swimmer’s itch (SI) is a dermatitis in humans caused by cercariae of avian and mammalian schistosomes which emerge from infected snails on a daily basis. Mitigation methods for SI have long been sought with little success. Copper sulfate application to the water to kill the snail hosts is the historically employed method, but is localized, temporary, and harmful to many aquatic species. Here, we test an alternative method to control Trichobilharzia stagnicolae, a species well-known to cause SI in northern Michigan and elsewhere in North America. Summer relocation of broods of the only known vertebrate host, common merganser (Mergus merganser), …

An Underwater Clash Of Spears: Public Engagement In Mediterranean Lionfish Control Efforts, Ioannis Savva, Leda L. Cai, Periklis Kleitou, Louis Hadjioannou, Carlos Jimenez, Anastasis Karonias, Erato Nicolaou, Niki Chartosia, Jason M. Hall-Spencer, Demetris Kletou

School of Biological and Marine Sciences

Invasive alien species pose a great challenge in conservation ecology. Rapid establishment of common lionfish (Pterois miles) in the eastern Mediterranean Sea and its ongoing westward expansion raises many questions about how to sustainably combat this invasion in the long term. Drawing on experiences from the western Atlantic invasion, citizen scientists were engaged and demonstrated the efficiency of long-term coordinated removals for the first time in the Mediterranean Sea. Findings reveal a sustained participation and interest throughout the coordinated removal events that encourage the organization of future events. Removal Action Teams were found effective at reducing lionfish numbers in small …

Genetic And Environmental Influence On Alcohol Intent And Alcohol Sips Among U.S. Children-Effects Across Sex, Race, And Ethnicity, Troy B. Puga, Yadi Liu, Peng Xiao, Ran Dai, Hongying Daisy Dai

Student Publications

Introduction: Alcohol intent (the susceptibility to initiating alcohol use) and alcohol sips (the initiation of alcohol) in youth are a multifactorial puzzle with many components. This research aims to examine the connection between genetic and environmental factors across sex, race and ethnicity.

Methods: Data was obtained from the twin hub of the Adolescent Brain Cognitive Development (ABCD) study at baseline (2016-2018). Variance component models were conducted to dissect the additive genetic (A), common (C) and unique environmental (E) effects on alcohol traits. The proportion of the total alcohol phenotypic variation attributable to additive genetic factors is reported as heritability (h2). …

International Consensus Statement On The Radiological Evaluation Of Dysraphic Malformations Of The Spine And Spinal Cord, Ankit Balani, Jai Sidpra, Sniya Sudhakar, Asthik Biswas, Özgür Öztekin, Valeria Capra, Martin Catala, Andrew J Copp, Neetu Kumar, Navroop Johal, M Zubair Tahir, Dominic Thompson, Dachling Pang, David M Mirsky, Mai-Lan Ho, Thierry A G M Huisman, Andrea Rossi, Kshitij Mankad

Children’s Nutrition Research Center Staff Publications

Dysraphic malformations of the spine and spinal cord (DMSSC) represent a spectrum of common congenital anomalies typically (though not exclusively) affecting the lower spinal segments. These may be responsible for varying degrees of neurologic, orthopedic, and urologic morbidity. With advances in neuroimaging, it is now possible to better diagnose and evaluate these disorders both prenatally and postnatally. Neuroimaging, performed at the right time and with technique optimization, is integral in guiding clinical management. However, the terminology used to describe these lesions has become increasingly confusing, and there is a lack of consensus regarding the essential radiologic features and their clinical …

High Resolution Spatial Profiling Of Kidney Injury And Repair Using Rna Hybridization-Based In Situ Sequencing, Haojia Wu, Eryn E Dixon, Qiao Xuanyuan, Juanru Guo, Yasuhiro Yoshimura, Chitnis Debashish, Anezka Niesnerova, Hao Xu, Morgane Rouault, Benjamin D Humphreys

2020-Current year OA Pubs

Emerging spatially resolved transcriptomics technologies allow for the measurement of gene expression in situ at cellular resolution. We apply direct RNA hybridization-based in situ sequencing (dRNA HybISS, Cartana part of 10xGenomics) to compare male and female healthy mouse kidneys and the male kidney injury and repair timecourse. A pre-selected panel of 200 genes is used to identify cell state dynamics patterns during injury and repair. We develop a new computational pipeline, CellScopes, for the rapid analysis, multi-omic integration and visualization of spatially resolved transcriptomic datasets. The resulting dataset allows us to resolve 13 kidney cell types within distinct kidney niches, …

Pulmonary Fibrosis Stakeholder Summit: A Joint Nhlbi, Three Lakes Foundation, And Pulmonary Fibrosis Foundation Workshop Report, Sydney B Montesi, Christian R Gomez, Michael Beers, Robert Brown, Ishanu Chattopadhyay, Kevin R Flaherty, Christine Kim Garcia, Brigitte Gomperts, Lida P Hariri, Cory M Hogaboam, R Gisli Jenkins, Naftali Kaminski, Grace Hyun J Kim, Melanie Königshoff, Martin Kolb, Darrell N Kotton, Jonathan A Kropski, Joseph Lasky, Chelsea M Magin, Toby M Maher, Mark Mccormick, Bethany B Moore, Cheryl Nickerson-Nutter, Justin Oldham, Anna J Podolanczuk, Ganesh Raghu, Ivan Rosas, Steven M Rowe, William T Schmidt, David Schwartz, Jessica E Shore, Cathie Spino, J Matthew Craig, Fernando J Martinez

Faculty, Staff and Students Publications

Despite progress in elucidation of disease mechanisms, identification of risk factors, biomarker discovery, and the approval of two medications to slow lung function decline in idiopathic pulmonary fibrosis and one medication to slow lung function decline in progressive pulmonary fibrosis, pulmonary fibrosis remains a disease with a high morbidity and mortality. In recognition of the need to catalyze ongoing advances and collaboration in the field of pulmonary fibrosis, the NHLBI, the Three Lakes Foundation, and the Pulmonary Fibrosis Foundation hosted the Pulmonary Fibrosis Stakeholder Summit on November 8–9, 2022. This workshop was held virtually and was organized into three topic …

Challenges Of Stray Cattle On Integrated Crop-Forage Resources In India, Pal Mahendra Singh

IGC Proceedings (1977-2023)

Field survey was conducted covering 1000 residents of district Udham Singh Nagar, Uttarakhand states of India in January 2022 including farmers, school teachers, students and residents of town and cities to study the ‘challenges and threats of stray animals on crop-forage resources in India. The survey indicated that 97.5, 75.6, 60.0, 77.8%, and 68.9 respondents had strong opinion that stray cattle were the serious threat to crops-forage resources, biodiversity, road accidents, transmitting harmful diseases and human-wildlife conflict, respectively, while 85.5, 67.7, 62.7,76.2 and 70.5% respondents gave their consent to solve stray cattle by opening of cowsheds, strict government policies, mass …

Optimizing Production Technology For Sustainable Organic Fodder Production And Soil Health In Indo-Gangetic Plains Of India, Pal Mahendra Singh

IGC Proceedings (1977-2023)

Field experiment was carried at Instructional Dairy Farm, G B Pant University of Agriculture & Technology, Pantnagar (India) during 2020-21 and 2021-22 to optimize the production technology for sustainable organic fodder production and soil health in Indo-Gangetic plains of India. Among the organic production systems, application of vermicompost @ 5 t/ha gave the highest fodder yield, gross return and net return but the B:C ratio was derived highest from zero budget natural farming. Among the Kharif crops grown in different cropping systems, BN hybrid intercropped with cowpea gave the significant higher green and dry fodder yield, gross return, net return …

The Combined Role Of Microbes And Forages In Animal Productivity, K. Panke-Buisse

IGC Proceedings (1977-2023)

Agricultural systems, particularly ruminant systems, are underpinned by diverse, functional microbial communities—in the soil, forage, silo, and rumen. We have relied on the jobs they perform on our behalf, but only recently have we been able to look “under the hood” at the membership and mechanisms within these microbiomes and begin to think about optimization. Ensiling is a common method of forage preservation globally and represents a highly intensive intersection between forage and microbiology, which has been shown to have beneficial effects on forage quality and dairy animal performance. However, observations of enhanced productivity, especially in the context of inoculated …

Determining ‘Wether’ Social Behaviour Or Pasture Quality Drives Sheep Grazing Patterns Using Random Forest Modelling, D. J. Parnell, L. Ingram, J. Edwards

IGC Proceedings (1977-2023)

Monitoring livestock provides valuable insights into the spatial distribution, foraging patterns, and animal behaviour, which may lead to the improved management of livestock. This objective of study was to understand what variables were significant in determining where sheep spent the most time in paddocks of native (dominated by Poa spp., Stipa spp., and Hordeum leporinum), and improved (Phalaris aquatica, Festuca spp., and Trifolium subterraneum) pastures (~24 ha-1 in size). Castrated male sheep, wethers, were tracked using GPS collars on a property located in the Monaro region of Southern New South Wales, Australia. Trials were performed over …

Ruminant Agriculture: A Tool For Climate Change Mitigation, B. L. Peterson Munks, M. Rellaford, J. Shanahan, S. Urbanowitz, F. Wang, S. Wang, Y. Zhao, E. Bender

IGC Proceedings (1977-2023)

The quest to address and mitigate climate change has been dubbed a “wicked problem” as it involves many interconnected processes requiring a multifaceted, comprehensive approach. Animal agriculture contributes roughly 15% to CO2 equivalent (CO2e) emissions; as a result, a concerted effort is being made to develop and promote more climate-friendly production practices. These practices include species diversification in grasslands, improving grazing rotation, adding nitrogen amendments, and the use of feed additives to reduce enteric fermentation. Successful inter-seeding of legumes and deep-rooted native grasses increases soil organic carbon (SOC) pools in many systems by increasing the biological carbon inputs to the …

Economics And Other Factors Affecting The Adoption Of Novel Endophyte Technology, M. H. Poore, J. Horner

IGC Proceedings (1977-2023)

Endophyte infected tall fescue impacts cattle and other livestock across vast regions of the world. Toxicosis from wild type endophyte is widespread in regions where toxic tall fescue is the base perennial forage. The Alliance for Grassland Renewal was founded to address this complex issue and to facilitate appropriate adoption of Novel Endophyte Tall Fescue, the only potentially 100% effective remedy for fescue toxicosis. A poor understanding of the Cost/Benefit ratio of renovating pasture is one of the main reason farmers give for not renovating tall fescue pastures. An Excel-based spreadsheet tool was developed by University of Missouri Extension to …

Physiological And Behavioral Responses Of Heifers That Graze Tall Fescue Infected By Wild-Type Or Novel Endophytes, S. Poudel, A. Halili, L. Wright, G. Pent, J. Fike

IGC Proceedings (1977-2023)

Fescue toxicosis presents serious challenges and huge economic losses to the beef industry in the U.S. Replacing tall fescue (TF) infected by wild-type endophyte (WE) with TF infected by novel endophyte can eliminate this problem but adoption of this technology has been limited. We aimed at demonstrating the physiological and behavioral responses of heifers that grazed either WE or NE TF using relatively non-invasive techniques. Angus or Angus cross heifers (n = 24) were assigned to either WE or NE pastures for a 56-d grazing period during the summers of 2020 and 2021. Heifer ADG and hair retention scores were …

Smallholder Zebu And Forage Production Development In Central Madagascar, L. Randriamanalina, M. S. Vorontsova, M. T. Rajaonah, O. P. Nanjarisoa, C. E. R. Lehmann, D. Miharinjanahary, H. N. S. Ratovoarinjaka, A. Bendrainy, C. Rijaniaina, A. M. Rabendrina, D. Rabeharison, B. F. Rakotozafy, F. Rakotoarison, D. Tahirinirainy, T. Randriamboavonjy, H. Ralimanana, J. Raharimampionona, C. Birkinshaw, W. Truter

IGC Proceedings (1977-2023)

Poverty in the Central Highlands of Madagascar is partly driven by inefficient exploitation of native forages and poor livestock nutrition. Zebus are of importance as cultural symbols, but this tradition has grown disconnected from agricultural policy. This project is working with three central highland communities near the protected areas of Itremo, Ibity and Ankafobe, to boost rangeland productivity and trial management methods which will support key forage grasses and improve livestock nutrition. A severe nitrogen deficiency compounded by extremely acidic soil conditions and low phosphorus is observed across the three sites. The lowest grazing capacity of an estimated 0.7 livestock …

Dry Season Feeding Strategies And Winter Forage Production By Communal Area Sheep Farmers Of The Eastern Cape Province In South Africa, B. Moyo, K. E. Ravhuhali

IGC Proceedings (1977-2023)

Experimental research into the possibility of employing winter forages as a low-cost, high-quality winter supplement has produced promising outcomes. The extent, challenges, and mitigation strategies of communal farmers involved in winter fodder production in the Eastern Cape are unknown. This study examines farmers' knowledge, attitudes, and perceptions of winter fodder production, its difficulties, and perceived advantages for communal sheep farmers. The study was carried out in the Swartwater communal area of the Eastern Cape province of South Africa. Thirty-two sheep farmers who cultivate winter forage were interviewed using a structured questionnaire. Using SPSS 17, descriptive statistics were produced for the …

Harvesting Site Influenced The Concentration Level Of Nitrogen And Mineral Status Of Woody Species In Semi-Arid Areas Of South Africa, K. E. Ravhuhali, H. S. Mudau, H. K. Mokoboki, B. Moyo, L. E. Motsei

IGC Proceedings (1977-2023)

Feed shortages in semi-arid areas cause a major set-back for livestock production. An understanding of the nutritive value of woody species in most parts of savanna regions can be vital to predicting what these species can offer for livestock productivity. The study assessed the variation in nitrogen and mineral concentration of leaves of woody species as influenced by harvesting site in South Africa. The study sites were communal areas in Limpopo and North West provinces. A total of 52 browse species were selected and used for this study. All statistical tests showed that there was a significant effect of species …

Winter Herbage Mass Accumulation And Animals Grazing Days Of Set Stocking Or Cell Grazing Dairy X Beef Systems In Southwest England, M. J. Rivero, Sarah Morgan, Maite Fajardo, G. Irisarri, P. Chilibroste

IGC Proceedings (1977-2023)

Cell grazing (CG) has shown to increase the production per hectare by allowing higher stocking rates, greater grass production and higher herbage utilisation throughout the grazing season compared to set stocking (SS). Our objective was to compare the herbage growth rate during winter resting (WHGR, October/November to April) and the animals grazing days per ha (AGD-ha) of CG and SS systems grazed by dairy x beef steers. Three 1.75ha (1.5ha in 2018) plots and three 1.0ha were used for the SS and CG, respectively. Forty-two and 48 autumn born dairy x beef steer calves were split into six equal groups …

Operational Model Of The Alliance For Grassland Renewal, C. A. Roberts, J. G. Andrae

IGC Proceedings (1977-2023)

Novel endophyte tall fescue was developed over 20 years ago, and novel endophyte cultivars are among the most innovative cultivars developed in recent decades. Yet adoption of novel endophyte technology is slow. In order to expedite adoption, a diverse group of stakeholders self assembled as the Alliance for Grassland Renewal, a nonprofit organization that includes colleagues from the sectors of industry, university, government, and production. Since 2012, the Alliance has held workshops for producers, educators, and industry across the southeastern US, where tall fescue is the predominant pasture grass. Also since 2012, the Alliance has monitored and reported endophyte purity …

Economic Value Of Improving Feed Efficiency Of Beef Cows On Pasture, J. T. Biermacher, J. K. Rogers, D. Lalman, A. Holder, R. S. Walker

IGC Proceedings (1977-2023)

Dry matter intake of beef cows is based on a percentage of body weight, so as mature cow size increases, intake increases. Feed efficiency, or the amount of feed required to produce gain or maintain production, has a direct impact to the producer. That is, as mature cow weight increases, yearly maintenance costs increases due to higher feed costs. However, variation in feed efficiency exists within population. Some large cows consume the same or less dry matter as a smaller cow, but produce a larger calf. Conversly, some smaller cows consume the same or more as a large cow but …

Effects Of Concentrate Supplementation During Summer On Animal Performance And Heat Stress Of Angus Steers Grazing Native Grasslands In Uruguay, P. Rovira, P. Lorenzo

IGC Proceedings (1977-2023)

Research in temperate grasslands has addressed livestock supplementation (SUPL) mainly during winter, but more studies are needed on the impact of SUPL during summer where heat stress (HS) conditions may occur. The objective of this study was to evaluate the effects of summer SUPL on average daily gain (ADG), respiratory rate (RR), and body temperature (BT) of steers grazing native grasslands (60% TDN, 7.3% CP) in Uruguay (33°14'S, 54°15'W). Eighteen 15-month-old Angus steers (285±11 kg) were randomly assigned to 6 groups (2 treatments x 3 replicates) with free access to shade and water on a continuous stocking system (1.5 steer/ha) …

Bale Grazing To Improve Soil Fertility In Kentucky Pastures, N. Roy, J. W. Lehmkuhler

IGC Proceedings (1977-2023)

A long-term project on a small Kentucky beef farm has demonstrated that bale grazing is an effective means of improving soil fertility. With the cooperation of a beef cattle producer, Extension personnel have been able to measure improvements in soil fertility using both high density and moderate density bale grazing practices. Initial efforts demonstrate that high density bale grazing improved soil fertility quickly by increasing soil test phosphorus from 15 to 45 ppm and potassium from 52 to 175 ppm on Melich III soil test extraction method. High density bale grazing was also shown to serve as a strategy to …

The Effects Of Grazing Cover Crops On Animal Performance And Soybean Production, J. Brett Rushing, Rocky Lemus, J. G. Maples, J. C. Lyles

IGC Proceedings (1977-2023)

Grazing cover crops has the potential to offset costs incurred with cover crop establishment, thus incentivizing management adoption. Information regarding cover crop species in combination with grazing and their subsequent effects on soybean production is limited. A field trial was conducted in Newton, MS from 2019 to 2021 to assess these effects. Cover crop treatments included oats (O), O + crimson clover (OC), and OC + radish (OCR) were applied in a randomized complete block design with three replications. Cover crops differed in nutritive analysis; O had significantly lower mean CP, but greater total daily nutrients (TDN). Weaned beef steers …