Digital Commons Network^™

Coping Strategies And Stress Of The Undergraduate Nursing Student In The Clinical Setting: An Evidence Based Practice Quantitative Study, Ashley Calverley

Electronic Theses and Dissertations

The assessment of perceived stress and coping behaviors related to first-semester clinical might benefit students in nursing education. The assessment of most common coping behaviors and perceived stress related to the clinical setting is essential due to difference in personalities, learning abilities, and coping behaviors among nursing students today. Previous research has suggested the initial clinical period results in adverse outcomes, such as poor academic performance, elevated burnout levels, and diminished personal well-being. These factors are detrimental to academic success in nursing programs. Evidence supports that helping students develop positive stress/coping abilities will aid in adapting in both the academic …

Extramedullary Hematopoiesis In Cancer, Derek A G Barisas, Kyunghee Choi

2020-Current year OA Pubs

Hematopoiesis can occur outside of the bone marrow during inflammatory stress to increase the production of primarily myeloid cells at extramedullary sites; this process is known as extramedullary hematopoiesis (EMH). As observed in a broad range of hematologic and nonhematologic diseases, EMH is now recognized for its important contributions to solid tumor pathology and prognosis. To initiate EMH, hematopoietic stem cells (HSCs) are mobilized from the bone marrow into the circulation and to extramedullary sites such as the spleen and liver. At these sites, HSCs primarily produce a pathological subset of myeloid cells that contributes to tumor pathology. The EMH …

Engineered Tissue Geometry And Plakophilin-2 Regulate Electrophysiology Of Human Ipsc-Derived Cardiomyocytes, Daniel W Simmons, Ganesh Malayath, David R Schuftan, Jingxuan Guo, Kasoorelope Oguntuyo, Ghiska Ramahdita, Yuwen Sun, Samuel D Jordan, Mary K Munsell, Brennan Kandalaft, Missy Pear, Stacey L Rentschler, Nathaniel Huebsch

2020-Current year OA Pubs

Engineered heart tissues have been created to study cardiac biology and disease in a setting that more closely mimics

Collaborative Fisheries Research Reveals Reserve Size And Age Determine Efficacy Across A Network Of Marine Protected Areas, Shelby L. Ziegler, Rachel O. Brooks, Lyall F. Bellquist, Jennifer E. Caselle, Steven G. Morgan, Timothy J. Mulligan, Benjamin I. Ruttenberg, Brice X. Semmens, Richard M. Starr, Joe Tyburczy, Dean E. Wendt, Andre Buchheister, Jose R.Marin Jarrin, Christina Pasparakis, Salvador J. Jorgensen, Jennifer A. Chiu, Jordan Colby, Connor L. Coscino, Leon Davis

Faculty Research, Scholarly, and Creative Activity

A variety of criteria may influence the efficacy of networks of marine protected areas (MPA) designed to enhance biodiversity conservation and provide fisheries benefits. Meta-analyses have evaluated the influence of MPA attributes on abundance, biomass, and size structure of harvested species, reporting that MPA size, age, depth, and connectivity influence the strength of MPA responses. However, few empirical MPA evaluation studies have used consistent sampling methodology across multiple MPAs and years. Our collaborative fisheries research program systematically sampled 12 no-take or highly protective limited-take MPAs and paired fished reference areas across a network spanning 1100 km of coastline to evaluate …

Protect The Children, Body And Soul, Kenjus T. Watson, Tiffani Marie, Ersie Anastasia Gentzis, Dante Dixson

Faculty Research, Scholarly, and Creative Activity

This paper critically examines American schooling systems, challenges their subtractive nature, and juxtaposes it with the culturally sustaining potential of education. We problematize the current tools for evaluating trauma and stress in young people of color and emphasize the need for a comprehensive understanding of indigenous medicines as a remedy. Drawing on interdisciplinary theories, we elucidate the pervasive and evolving nature of anti-blackness, reinforcing the sociohistorical structure of inequity within schools. As a response, this study presents a unique wellness survey (comprising two newly validated wellness scales) developed from a previous four-year longitudinal study investigating the relationship between culturally relevant …

Meta-Interpretive Learning With Reuse, Rong Wang, Jun Sun, Cong Tian, Zhenhua Duan

Research Collection School Of Computing and Information Systems

Inductive Logic Programming (ILP) is a research field at the intersection between machine learning and logic programming, focusing on developing a formal framework for inductively learning relational descriptions in the form of logic programs from examples and background knowledge. As an emerging method of ILP, Meta-Interpretive Learning (MIL) leverages the specialization of a set of higher-order metarules to learn logic programs. In MIL, the input includes a set of examples, background knowledge, and a set of metarules, while the output is a logic program. MIL executes a depth-first traversal search, where its program search space expands polynomially with the number …

Heterozygous Loss-Of-Function Variants In Dock4 Cause Neurodevelopmental Delay And Microcephaly., Charlotte Herbst, Viktoria Bothe, Meret Wegler, Susanne Axer-Schaefer, Séverine Audebert-Bellanger, Jozef Gecz, Benjamin Cogne, Hagit Baris Feldman, Anselm H C Horn, Anna C E Hurst, Melissa A. Kelly, Michael C. Kruer, Alina Kurolap, Annie Laquerriere, Megan Li, Paul R. Mark, Markus Morawski, Mathilde Nizon, Tomi Pastinen, Tilman Polster, Pascale Saugier-Veber, Jang Sesong, Heinrich Sticht, Jens T. Stieler, Isabelle Thiffault, Clare L. Van Eyk, Pascale Marcorelles, Myriam Vezain-Mouchard, Rami Abou Jamra, Henry Oppermann

Manuscripts, Articles, Book Chapters and Other Papers

Neurons form the basic anatomical and functional structure of the nervous system, and defects in neuronal differentiation or formation of neurites are associated with various psychiatric and neurodevelopmental disorders. Dynamic changes in the cytoskeleton are essential for this process, which is, inter alia, controlled by the dedicator of cytokinesis 4 (DOCK4) through the activation of RAC1. Here, we clinically describe 7 individuals (6 males and one female) with variants in DOCK4 and overlapping phenotype of mild to severe global developmental delay. Additional symptoms include coordination or gait abnormalities, microcephaly, nonspecific brain malformations, hypotonia and seizures. Four individuals carry missense variants …

People With Degenerative Cervical Myelopathy Have Impaired Reactive Balance During Walking, Timothy F. Boerger, Learon Mcginn, Megan Bellman, Marjorie C. Wang, Brian D. Schmit, Allison S. Hyngstrom

Physical Therapy Faculty Research and Publications

Background

People with degenerative cervical myelopathy are known to have impaired standing balance and walking abilities, but less is known about balance responses during walking.

Research question

The aim of this project was to assess reactive balance impairments during walking in people with degenerative cervical myelopothy (PwDCM). We hypothesized that center of mass motion following perturbations would be larger in PwDCM and gluteus medius electromyographic amplitude responses would be decreased in PwDCM.

Methods

Reactive balance responses were quantified during unanticipated lateral pulls to the waist while treadmill walking. Walking biomechanics data were collected from 10 PwDCM (F=6) and 10 non-myelopathic …

Evaluation Of Fall And Winter Trinexapac-Ethyl Applications On Ultradwarf Bermudagrass Putting Green Color, Quality, And Green Cover, J. C. Booth, W. J. Hutchens, S. D. Askew, J. M. Goatley, X. Zhang, D. S. Mccall

Horticulture Faculty Publications and Presentations

Ultradwarf bermudagrass (UDB) putting greens grown in subtropical and temperate climates can face elevated risk of winter injury from cold temperatures. Trinexapac-ethyl (TE) inhibits UDB growth potentially reducing spring green-up and overexertion of carbohydrate reserves for UDB during the cold de-acclimation period. A field study was conducted to determine the effect of fall and winter TE applications on the visual quality and color of UDB putting greens in Virginia from the cold acclimation phase through the cold de-acclimation phase. A second controlled-environment study was conducted to determine how TE applications to UDB during cold acclimation affected UDB cold tolerance. In …

The Relevance Of Arterial Blood Pressure In The Management Of Glaucoma Progression: A Systematic Review, Jan Van Eijgen, Jesus D. Melgarejo, Jana Van Laeken, Claire Van Der Pluijm, Hanne Matheussen, Micheline Verhaegen, Karel Van Keer, Gladys E. Maestre, Lama A Al Aswad, Ingeborg Stalmans

School of Medicine Publications

Background: Glaucoma is one of the leading causes of global blindness and is expected to co-occur more frequently with vascular morbidities in the upcoming years, as both are aging-related diseases. Yet, the pathogenesis of glaucoma is not entirely elucidated and the interplay between intraocular pressure, arterial blood pressure (BP) and ocular perfusion pressure is poorly understood.

Objectives: This systematic review aims to provide clinicians with the latest literature regarding the management of arterial BP in glaucoma patients.

Methods: A systematic search was performed in Medline, Embase, Web of Science and Cochrane Library. Articles written in English assessing the influence of …

Widespread, Depth-Dependent Cortical Microstructure Alterations In Paediatric Focal Epilepsy, Chiara Casella, Katy Vecchiato, Daniel Cromb, Yourong Guo, Anderson M. Winkler, Emer Hughes, Louise Dillon, Elaine Green, Kathleen Colford, Alexia Egloff

School of Medicine Publications

Objective

Tissue abnormalities in focal epilepsy may extend beyond the presumed focus. The underlying pathophysiology of these broader changes is unclear, and it is not known whether they result from ongoing disease processes, treatment-related side-effects, or whether they emerge earlier. Few studies have focused on the period of onset for most focal epilepsies, childhood. Fewer still have utilised quantitative MRI, which may provide a more sensitive and interpretable measure of tissue microstructural change. Here, we aimed to determine common spatial modes of changes in cortical architecture in children with heterogeneous drug-resistant focal epilepsy and, secondarily, whether changes were related to …

Current And Future Approaches To Pediatric Anxiety Disorder Treatment, André Zugman, Anderson M. Winkler, Purnima Qamar, Daniel Samuel Pine

School of Medicine Publications

This overview critically appraises the literature on the treatment of pediatric anxiety disorders. The two established treatments for these conditions comprise cognitive-behavioral therapy (CBT) and antidepressant medications. Many youths receiving these treatments fail to achieve remission, which creates a need for new treatments. After summarizing the literature on CBT and currently available medications, the authors describe research that lays a foundation for improvements in the treatment of pediatric anxiety disorders. This foundation leverages neuroscientific investigations, also described in the overview, which provide insights on mechanisms of successful treatment.

Contemplating On The End Of Integrated Care-Part Ii: Living The Questions To Foster Adaptability, Deepu George, Parinda Khatri

School of Medicine Publications

This article extends the use of the ecocycle planning framework to describe challenges ahead for the integrated care and Collaborative Family Healthcare Association (CFHA). The authors make the case that to remain agile and adaptable, there are contextual, ecological, and moral challenges that integrated care and CFHA should keep in the forefront as they navigate the future of an inequitable health care system that is morphing at a rapid pace. These influences include but are not limited to challenges of social determinants of health, artificial intelligence, generational differences in technology among older and younger populations, the moral issue of poverty, …

Evaluation Of Exploratory Fluid Biomarker Results From A Phase 1 Senolytic Trial In Mild Alzheimer's Disease, Miranda E. Orr, Valentina R. Garbarino, Juan Pablo Palavicini, Justin Melendez, Nicolas Barthelemy, Yingxin He, Tiffany F. Kautz, Marisa Lopez-Cruzan, Julia Mathews, Peng Xu, Bin Zhan

School of Medicine Publications

Senescent cell accumulation contributes to the progression of age-related disorders including Alzheimer's disease (AD). Clinical trials evaluating senolytics, drugs that clear senescent cells, are underway, but lack standardized outcome measures. Our team recently published data from the first open-label trial to evaluate senolytics (dasatinib plus quercetin) in AD. After 12-weeks of intermittent treatment, we reported brain exposure to dasatinib, favorable safety and tolerability, and modest post-treatment changes in cerebrospinal fluid (CSF) inflammatory and AD biomarkers using commercially available assays. Herein, we present more comprehensive exploratory analyses of senolytic associated changes in AD relevant proteins, metabolites, lipids, and transcripts measured across …

Microplastics In Atlantic Ribbed Mussels (Geukensia Demissa) From The Delaware Inland Bays, Usa, Jeffrey Ashley, Amanda Pilat, Ariana Ohlweiler, Connor Ogden, Priya Modi, Spencer Talbot, Caya Smith, Justin O'Pella, Gulnihal Ozbay

Student Papers, Posters & Projects

Due to the prevalence of plastic pollution in coastal ecosystems, aquatic organisms are at high risk for accumulating microplastics (MPs). Filter-feeding bivalves, such as mussels and oysters, may be exposed to, and subsequently accumulate, MPs due to the high volume of water they pass through their bodies. This study assessed the levels of MPs within Atlantic ribbed mussels (Geukensia demissa), a common filter feeder found along the United States Atlantic Coast, from 12 sites within Rehoboth Bay, Indian River Bay, and Little Assawoman Bay, collectively known as the Delaware Inland Bays. Composited mussels from each site were digested using potassium …

Predictive Understanding Of Lake Water Temperature And Dissolved Oxygen Profiles Across The Red River Basin Through Interpretable Machine Learning, Isabela Suaza Sierra

Open Access Theses & Dissertations

Accurately predicting lake water temperature (LWT) and dissolved oxygen (DO) is crucial for determining threshold values of fish survivability under warmer global conditions, with recreational fishing in reservoirs significantly contributing to regional economies, such as $779 million and $1,891 million annually to the economies of Oklahoma and Texas, respectively. Current mathematical models for temperature and oxygen profiles, which incorporate multi-layer and turbulent mixing equations, are complex and challenging to parameterize, particularly due to uncertainties in acquiring sufficient data for training and validation. Leveraging the flexibility and information extraction power of machine learning (ML) methods, this master thesis aimed to set …

Antioxidant Properties Of Kombucha Beverage Infused With Ganoderma Lucidum And Green Tea From Camellia Sinensis (L.) Kuntze With Several Fermentation Times, Rizki Rabeca Elfirta, Pamungkas Rizki Ferdian, Iwan Saskiawan, Tri Hadi Handayani, Kayla Faza Gustafri Mandalika, Rini Riffiani, Kasirah Kasirah, Ukhradiya Magharaniq Safira Purwanto

Karbala International Journal of Modern Science

Kombucha is a functional beverage produced through the fermentation of infused tea or Camelia sinensis (L.) Kuntze (CS) by a symbiotic culture of bacteria and yeast. Apparently, the substrate of kombucha can be substituted to enhance its functional properties. Ganoderma lucidum (GL) is a potential substrate reported to have health benefits. This study aims to evaluate antioxidant properties by comparing different formulations and fermentation times. The formulations prepared in the present study varied in the compositions of GL and CS substrates, namely F1 (100% GL), F2 (75% GL: 25% CS), F3 (50% GL: 50% CS), F4 (25% GL: 75% CS), …

Overview Of The Zoonotic Potential And Coinfection Of Sars-Cov-2 In Indonesia, Muhammad Khaliim Jati Kusala, Ni Luh Putu Indi Dharmayanti

Karbala International Journal of Modern Science

In the ASEAN region, Indonesia has the highest overall COVID-19 infection score. The SARS-CoV-2 pandemic first emerged in China and then transmitted sporadically throughout the world. Animals and humans can be infected with the corona virus, so this disease is classified as a zoonotic disease. This review aims to gather information regarding the potential of SARS-CoV-2 as a zoonotic disease and coinfections with several other pathogens in Indonesia. This study collected data demonstrating the potential for COVID-19 to be transmitted from humans to animals, as an evidenced by positive test results for the Bat Coronavirus Antigen in bats. Cats have …

Professional Identity Development Of Black Doctoral Students In Counselor Education: A Reflexive Model, Olivia T. Ngadjui Phd, Elizabeth A. Doughty Horn

Teaching and Supervision in Counseling

This grounded theory study comprised the perspectives of how past and current Black doctoral students formalized their professional identity in counselor education. Findings included reflexivity as a central theme within the internal process of Black doctoral students navigating counselor education programs and a model of professional identity development.

Wheat Landraces, Small Farmers And Urban Consumers: Revival Of Einkorn In Turkey, Nurcan Atalan Helicke

Journal of Critical Global Issues

Cultivated for more than 10,000 years, wheat (Triticum) is one of the world’s most widely grown and important crops. Wheat has sustained humans for thousands of years in a multitude of ways. In recent years, there has been a global movement to revive wheat landraces. Landraces are typically adapted to a local area and to traditional farming systems. This article examines the revival of wheat landrace, einkorn (Triticum monoccoccum L. subsp. monoccoccum) through a case study of Turkey. There is limited literature examining the interaction of actors in decision-making processes that balance subsistence and market motivations. …

Environmental Analysis Of Codfish Production And Consumption In Portugal, Ayla Frost, Joana Almeida, Joana Dionisio, Radu Godina, Cátia Magro

Journal of Critical Global Issues

Codfish, a typical dish consumed frequently in Portugal, is fished in the cold Northern Atlantic waters far from the Portuguese coast. Thus, regional tensions and the environmental impacts of Portuguese codfish importation and production are significant current issues. The present study uses a life cycle assessment methodology to evaluate the array of environmental impacts of the production of 1 kg of codfish, following a cradle to gate approach. The life cycle inventory was grouped into catch and preprocessing, transit, and curing stages. The data collection of products and processes in each stage was based on scientific peer reviewed documents, technical …

Extracellular Vesicle-Mediated Transfer Of Doc2b: Unveiling Tumor-Suppressive Mechanisms In Cervical Cancer, Sangavi Eswaran, Shama Prasada Kabekkodu

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Diagnosis And Treatment Of Ovarian Cancer Using Magnetic Nanoparticles, E John, T Anil

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Effect Of Altered Glucose Levels On Fatty Acid Synthase Enzyme And Downstream Fatty Acids In Extracellular Vesicles, Namita N Kashyap, Dinesh Upadhya

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Identification Of Nano-Peptides Affecting Tumorigenesis From Rna-Seq Data, Sandeep Mallya

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Homeopathy - Modern Medicine Interface: Nanofibrous Scaffolds Loaded With Homoeopathic Mother Tincture For Wound Healing Applications., Ankitha Suresh, Deiviga Murugan, Bhisham Narayan Singh

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanocellulose As Biopolymer And Its Applications In Biomedical Field, Vinay Pj, Pradeep H K, Tanuja N Rajaput, Shwetha S Marigoudar, Girish Bolakatti

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Insights Into Novel Biomaterials For Dura Mater Substitutes For Improved Dural Closure, Dolphee Khurana, Ankitha Suresh, Bhisham Narayan Singh

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Magnetic Nanoparticles: Recent Advancements For Biomedical Applications, Kajal Kumari, Venkatesh Kamath B

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Innovative Approaches To Nano-Endodontics, Supreet Kaur, Shashi Rashmi Acharya, Sandya Kini

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.