Digital Commons Network^™

Preliminary Investigation Of Differences In Host Mitochondria Membrane Potential During Toxoplasma Gondii Infection, Bryan L. Ortega

USF Tampa Graduate Theses and Dissertations

Toxoplasma gondii is an obligate intracellular protozoan with a broad host range of hosts, including various warm-blooded mammals, including humans. While infections can often be asymptomatic in immunocompetent individuals, they can pose significant risks to those who are immunocompromised, as well as pregnant women. Toxoplasmosis represents a significant burden on public health in the United States, with over 800,000 annual infections reported, often leading to severe complications such as symptomatic eye disease and congenital infections. Recent attention has developed regarding its potential association with human neuropathies such as Alzheimer's disease, dementia, and mood disorders. This project investigated differences in host …

Author Correction: Hypomorphic Brca2 And Rad51c Double Mutant Mice Display Fanconi Anemia, Cancer And Polygenic Replication Stress, Karl-Heinz Tomaszowski, Sunetra Roy, Carolina Guerrero, Poojan Shukla, Caezaan Keshvani, Yue Chen, Martina Ott, Xiaogang Wu, Jianhua Zhang, Courtney D Dinardo, Detlev Schindler, Katharina Schlacher

Faculty, Staff and Student Publications

No abstract provided.

A Biogeographical Appraisal Of The Threatened South East Africa Montane Archipelago Ecoregion, Julian Bayliss, Gabriela B Bittencourt-Silva, William R Branch, Carl Bruessow, Steve Collins, T Colin E Congdon, Werner Conradie, Michael Curran, Savel R Daniels, Iain Darbyshire, Harith Farooq, Lincoln Fishpool, Geoffrey Grantham, Zacharia Magombo, Hermenegildo Matimele, Ara Monadjem, Jose Monteiro, Jo Osborne, Justin Saunders, Paul Smith, Claire N Spottiswoode, Peter J Taylor, Jonathan Timberlake, Krystal A Tolley, Érica Tovela, Philip J Platts

Faculty, Staff and Student Publications

Recent biological surveys of ancient inselbergs in southern Malawi and northern Mozambique have led to the discovery and description of many species new to science, and overlapping centres of endemism across multiple taxa. Combining these endemic taxa with data on geology and climate, we propose the 'South East Africa Montane Archipelago' (SEAMA) as a distinct ecoregion of global biological importance. The ecoregion encompasses 30 granitic inselbergs reaching > 1000 m above sea level, hosting the largest (Mt Mabu) and smallest (Mt Lico) mid-elevation rainforests in southern Africa, as well as biologically unique montane grasslands. Endemic taxa include 127 plants, 45 vertebrates …

Evaluation Of Treatment Parameters For Focused-Extracorporeal Shock Wave Therapy In Knee Osteoarthritis Patients With Bone Marrow Lesions: A Pilot Study, Hani Al-Abbad, Jacqueline E Reznik, Erik Biros, Bruce Paulik, Rob Will, Samuel Gane, Penny Moss, Anthony Wright

Faculty, Staff and Student Publications

OBJECTIVES: To evaluate the effect of different dosage parameters of focused-extracorporeal shock wave therapy on pain and physical function in knee osteoarthritis patients with bone marrow lesions. In addition, to investigate pathophysiological changes based on imaging and biomarker measures.

METHODS: Using a single-case experimental design, a total of 12 participants were randomly allocated in 4 equal groups of 3 to receive different dosages of focused-extracorporeal shock wave therapy. Each group received either 4 or 6 sessions of 1500 or 3000 shocks over 4 or 6 weekly sessions. Participants underwent repeated measurements during the baseline, intervention, and post-intervention phases for Western …

Comparison Of Conventional And Adaptive Acoustic Beamforming Algorithms Using A Tetrahedral Microphone Array In Noisy Environments, Megan Brittany Ewers

Dissertations and Theses

In situ acoustic measurements are often plagued by interfering sound sources that occur within the measurement environment. Both adaptive and conventional beamforming algorithms, when applied to the outputs of a microphone array arranged in a tetrahedral geometry, are able to capture sound sources in desired directions and reject sound from unwanted directions. Adaptive algorithms may be able to measure a desired sound source with greater spatial precision, but require more calculations and, therefore, computational power. A conventional frequency-domain phase-shift algorithm and a modified adaptive frequency-domain Minimum Variance Distortionless Response (MVDR) algorithm were applied to simulated and recorded signals from a …

Synchrony In Networks Of Type 2 Interneurons Is More Robust To Noise With Hyperpolarizing Inhibition Compared To Shunting Inhibition In Both The Stochastic Population Oscillator And The Coupled Oscillator Regimes, Roman Baravalle, Carmen C. Canavier

School of Medicine Faculty Publications

Synchronization in the gamma band (25–150 Hz) is mediated by PV+ inhibitory interneurons, and evidence is accumulating for the essential role of gamma oscillations in cognition. Oscillations can arise in inhibitory networks via synaptic interactions between individual oscillatory neurons (mean-driven) or via strong recurrent inhibition that destabilizes the stationary background firing rate in the fluctuation-driven balanced state, causing an oscillation in the population firing rate. Previous theoretical work focused on model neurons with Hodgkin’s Type 1 excitability (integrators) connected by current-based synapses. Here we show that networks comprised of simple Type 2 oscillators (resonators) exhibit a supercritical Hopf bifurcation between …

Use Of Lcp-Tacrolimus (Lcpt) In Kidney Transplantation: A Delphi Consensus Survey Of Expert Clinicians, Alexander Wiseman, Tarek Alhamad, Rita R Alloway, Beatrice P Concepcion, Matthew Cooper, Richard Formica, Christina L Klein, Vineeta Kumar, Nicolae Leca, Fuad Shihab, David J Taber, Sarah Mulnick, Donald M Bushnell, Monica Hadi, Suphamai Bunnapradist

2020-Current year OA Pubs

BACKGROUND LCPT (Envarsus XR®) is a common once-daily, extended-release oral tacrolimus formulation used in kidney transplantation. However, there are minimal evidence-based recommendations regarding optimal dosing and treatment in the de novo and conversion settings. MATERIAL AND METHODS Using Delphi methodology, 12 kidney transplantation experts with LCPT experience reviewed available data to determine potential consensus topics. Key statements regarding LCPT use were generated and disseminated to the panel in an online Delphi survey. Statements were either accepted, revised, or rejected based on the level of consensus, perceived strength of evidence, and alignment with clinical practice. Consensus was defined a priori as …

Novel Lipid Mediator 7s,14r-Docosahexaenoic Acid: Biogenesis And Harnessing Mesenchymal Stem Cells To Ameliorate Diabetic Mellitus And Retinal Pericyte Loss, Yan Lu, Haibin Tian, Hongying Peng, Quansheng Wang, Bruce A. Bunnell, Nicolas G. Bazan, Song Hong

School of Medicine Faculty Publications

Introduction: Stem cells can be used to treat diabetic mellitus and complications. ω3-docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and protective. This study found novel DHA-derived 7S,14R-dihydroxy-4Z,8E,10Z,12E,16Z,19Z-docosahexaenoic acid (7S,14R-diHDHA), a maresin-1 stereoisomer biosynthesized by leukocytes and related enzymes. Moreover, 7S,14R-diHDHA can enhance mesenchymal stem cell (MSC) functions in the amelioration of diabetic mellitus and retinal pericyte loss in diabetic db/db mice. Methods: MSCs treated with 7S,14R-diHDHA were delivered into db/db mice i.v. every 5 days for 35 days. Results: Blood glucose levels in diabetic mice were lowered by 7S,14R-diHDHA-treated MSCs compared to control and untreated MSC groups, accompanied by …

Edna Study Of The Kellogg-Mt. Scott Watershed, Amy D. Van Riessen

Urban Ecosystem Research Consortium of Portland/Vancouver

The Kellogg Creek Restoration and Community Enhancement Project is an exciting effort occurring in the heart of downtown Milwaukie. The project encompasses many elements, including:

• providing fish passage to 15 miles of habitat by removing the barrier at Kellogg Dam
• restoring 17 acres of high-quality habitat behind the dam
• providing public access and viewing points to encourage nature-based recreation and outdoor education
• increasing flood storage capacity to reduce flooding in lower Kellogg Creek
• modernizing the existing Oregon State Highway 99E bridge with an alternative that increases seismic resiliency and establishes a safe bike/pedestrian undercrossing
• providing interactive learning, scientific research and …

I Love Coyotes, But I Love My Cat Too: Community-Reported Emotional Responses To Canis Latrans In The Portland Metropolitan Area, Zuriel A. Van Belle

Urban Ecosystem Research Consortium of Portland/Vancouver

In an urban setting, coyote (Canis latrans) observations elicit a variety of reported emotional responses—including complex combinations, such as concern for humans and pets with love for nature and wildlife. The Portland Urban Coyote Project is a community science project that collects reported observations of coyotes in the Portland metropolitan area and provides outreach materials to the community. Since 2013, the project has collected over 16,000 reported observations of coyotes.

In 2021, the report form was updated to include the question "How did you feel about this observation?" with a 5-point Likert scale from very negative to very …

Vaux’S Swifts In Portland – 15 Years Of Monitoring An Iconic Bird, Candace Larson, Joe Liebezeit, Mary Coolidge

Urban Ecosystem Research Consortium of Portland/Vancouver

For 15 year, Portland Audubon has counted migrating Vaux’s Swifts at Chapman Elementary School and other sites in the Portland region as part of a community science effort to monitor fall chimney roost site use, safeguard key roosting sites from disturbances, and educate the public on the protection of this species of concern. Data are contributed annually to a larger West Coast wide tracking effort. Vaux’s Swift population numbers have been declining for several decades, likely due primarily to habitat loss. This species historically utilized large hollowed out old-growth tree snags to roost. Now, many depend on large chimneys as …

Charting A Path Toward An Indigenous History Of Florida, Denise I. Bossy

Florida Historical Quarterly

In 1743, with the naive belief that the Calusas were finally interested in Catholic conversion, two Jesuit missionaries traveled to South Florida from Havana, Cuba. For decades Europeans described the region-in documents and on maps-as all but devoid of human life and, in particular, its Indigenous populations as being virtually extinct. Instead, the Jesuits discovered that South Florida was very much still under Indigenous control. A number of distinct Native confederacies-including one that consisted of Calusas, Bocarratons, and "Key" Indians and another of what one Spaniard called Maymies, Santaluzos, and Mayacas-exerted not only territorial control but also control over the …

Florida Historical Quarterly, Vol 100, No. 1, Florida Historical Society

Florida Historical Quarterly

No abstract provided.

Effects Of Urbanization On Dissolved Carbon And Nutrients In The Johnson Creek Watershed On Long-Term Temporal Scales, Jacob Rudolph, Jennifer L. Morse, Rebecca L. Hale

Urban Ecosystem Research Consortium of Portland/Vancouver

Dissolved organic carbon (DOC), the largest flux of carbon in streams, is a vital metric in urban stream ecology that is often overlooked, especially on seasonal scales. Microorganisms metabolize DOC, which can decrease dissolved oxygen and pH and harm other aquatic species. Johnson Creek watershed, located in the Portland metro area, provides an ideal location to study the effect of urbanization on DOC and water quality resulting from channelization and urban land. We hypothesize that DOC will increase downstream as impervious surface cover and urbanization increase. To quantify DOC concentration temporal changes, surface water samples were collected weekly from three …

Why Is The Oaks Bottom Reservoir So Dead And Brown? A Success Story Of Purple Loosestrife Control, Laura Guderyahn

Urban Ecosystem Research Consortium of Portland/Vancouver

Ever since the early 1990’s, when a water control structure was used to flood the 60acre ponded wetland at Oaks Bottom to increase waterfowl overwintering habitat, Purple Loosestrife (Lythrum salicaria) has thrived. Starting in 2008, Portland Parks and Recreation (PPR) and the Bureau of Environmental Services (BES) partnered with the Oregon Department of Agriculture (ODA) to annually release thousands of three different species of biocontrol beetles throughout the wetland. However, the unnatural flooding regime due to the water control structure and a greatly undersized culvert connecting the refuge to the Willamette River, resulted in annual reproductive and overwintering …

Proceedings Of The 22nd Annual Urban Ecology & Conservation Symposium (2024), Lori Hennings

Urban Ecosystem Research Consortium of Portland/Vancouver

These proceedings document the agenda and abstracts for presentations and posters from the 22nd annual conference (2024) organized by the Urban Ecosystem Research Consortium of Portland/Vancouver (UERC). The UERC is a consortium of people from various universities and colleges, state and federal agencies, local governments, non-profit organizations and independent professionals interested in supporting urban ecosystem research and creating an information-sharing network of people that collect and use ecological data in the Portland/Vancouver area. The annual conference has an open call for abstracts. The UERC organizing committee selects the final oral and poster presentations, along with 2 invited keynote presentations

Up-Regulation Of Non-Photochemical Quenching Improves Water Use Efficiency And Reduces Whole-Plant Water Consumption Under Drought In Nicotiana Tabacum, Benjamin Turc, Seema Sahay, Jared Haupt, Talles De Oliveira Santos, Geng Bai, Katarzyna Glowacka

Center for Plant Science Innovation: Faculty Publications

Water supply limitations will likely impose increasing restrictions on future crop production, underlining a need for crops that use less water per mass of yield. Water use efficiency (WUE) therefore becomes a key consideration in developing resilient and productive crops. In this study, we hypothesized that it is possible to improve WUE under drought conditions via modulation of chloroplast signals for stomatal opening by up-regulation of non-photochemical quenching (NPQ). Nicotiana tabacum plants with strong overexpression of the PsbS gene encoding PHOTOSYSTEM II SUBUNIT S, a key protein in NPQ, were grown under differing levels of drought. The PsbS-overexpressing lines lost …

Lanthorn, Vol. 58, No. 14, March 11, 2024, Grand Valley State University

Volume 58, August 7, 2023 - April 15, 2024

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

How To Identify Various Sparrow Species, Aidan Castricone '24, Alexis Larsen '24, Emma Barry '25

Biology Student Scholarship

A helpful infographic on how to differentiate between four little brown birds: the house sparrow, the song sparrow, the white-throated sparrow, and the swamp sparrow. Animal behavior (BIO 350/350L) final project

Seven Behaviors Exhibited In The Blue Jay, Gillian Chapleau '24, Jide Owoeye '23

Biology Student Scholarship

A quick guide to understanding common behaviors exhibited by blue jays. Animal behavior (BIO 350/350L) final project

Black Social Workers Use Of Racial Identity And Self Concept In The Workplace, Shielah Monique Deblanc

Walden Dissertations and Doctoral Studies

Navigating the Black professional identity in U.S. work environments poses challenges for social workers, with limited research addressing racial salience, power dynamics, and self-concept within their specific workplace contexts. Using self-concept theory, and the multidimensional model of racial identity as theoretical and conceptual frameworks, the purpose of this research was to examine Black social workers’ attitudes about self-concept using racial salience, power distance, and employee tenure as predictors. Using web-based surveys to collect data, a purposive sample of 77 participants were used to complete demographic information, a measure of centrality to gauge racial salience Multidimensional Inventory of Black Identity, a …

Blue Jays, Meriam Salo '25, Gabriela Guzman Reyes '24

Biology Student Scholarship

A guide to identifying blue jays, and understanding their common behaviors. Animal behavior (BIO 350/350L) final project

Exploring Practices Of Board-Certified Pediatric Clinical Specialst Physical Therapists In Addressing Needs Of Children Diagnosed With Autism Spectrum Disorder, Olga Chaikovsky

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

Background: Autism spectrum disorder (ASD) is a complex condition affecting multiple domains of development. Physical Therapists (PTs) are members of the interprofessional team addressing the needs of individuals with ASD. A lack of uniformity in evidence-based assessments and practices employed by therapists to address the needs of children with ASD exists in the literature. PTs often implement approaches that are not evidence-based but rather learned from more experienced professionals or discovered by trial and error.

Pediatric clinical specialist physical therapists (PCSPTs) are PTs who possess advanced education and clinical skills in Pediatrics. As pediatric experts, PCSPTs play a major …

Examining The Impact Of Stream Permanence On Headwater Stream Carbon Emissions, Hannah D. Conroy, Erin R. Hotchkiss, Kaelin M. Cawley, Keli Goodman, Jeremy B. Jones, Wilfred M. Wollheim, David Butman

Faculty Publications

Quantifying headwater stream carbon emissions is important for our understanding of the global carbon cycle because these emissions (an estimated 0.93-1.15 Pg C year) can be substantial compared to the terrestrial flux. Headwater stream networks can have high emissions due to their coupling with the terrestrial environment and high turbulence with some estimates predicting headwater stream networks can contribute 70% of the global riverine stream emissions. These carbon emissions are challenging to predict, especially with regards to headwater stream network spatiotemporal heterogeneity. The majority of headwater streams exhibit changes in stream network area on a seasonal basis, and these locations …

Mallards And Their Interesting Facts, Caitlin Mchugh '24, Jessica Slaton '24

Biology Student Scholarship

A guide on how to differentiate between male and female mallards, where to find these ducks, and their common behaviors. Animal behavior (BIO 350/350L) final project

Identifying The American Goldfinch, Margaret Low '24, Laura Mooney '24

Biology Student Scholarship

An infographic with tips on how to identify a common backyard visitor, the American goldfinch. Animal behavior (BIO 350/350L) final project

Messages From The Provost, Georgia Southern University

Messages from the Provost

Excellence in Action

Emerging Scholar

CPE: Free Community Programs

Good News

Congratulations Corner

Characterizing Multimorbidity Prevalence And Adverse Outcomes In Ethnically And Culturally Diverse Sub-Populations In India: Gaps, Opportunities, And Future Directions, Preeti Zanwar, Robyn Taylor, Tanisha Hill-Jarrett, Elena Tsoy, Jason Flatt, Zunera Mirza, Carl Hill, Arokiasamy Perianayagam

College of Population Health Faculty Papers

India is a large middle-income country and has surpassed China in overall population, comprising 20% of the global population (over 1.43 billion people). India is experiencing a major demographic shift in its aging population. Chronic diseases are common among older adults and can be persistent over the life course, lead to the onset of disability, and be costly. Among older adults in India, the existence of multiple comorbid chronic conditions (i.e., multimorbidity) is rapidly growing and represents a burgeoning public health burden. Prior research identified greater rates of multimorbidity (e.g., overweight/obesity diabetes, hypertension, cardiovascular disease, stroke, and malignancies) in minority …

Automating Data Analysis For Hydrogen/Deuterium Exchange Mass Spectrometry Using Data-Independent Acquisition Methodology, Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, Pauline Douglas, Stephen Coales, Rosa Viner, Aleem Syed, John A Tainer, Susan P Lees-Miller, David C Schriemer

Faculty, Staff and Student Publications

We present a hydrogen/deuterium exchange workflow coupled to tandem mass spectrometry (HX-MS2) that supports the acquisition of peptide fragment ions alongside their peptide precursors. The approach enables true auto-curation of HX data by mining a rich set of deuterated fragments, generated by collisional-induced dissociation (CID), to simultaneously confirm the peptide ID and authenticate MS1-based deuteration calculations. The high redundancy provided by the fragments supports a confidence assessment of deuterium calculations using a combinatorial strategy. The approach requires data-independent acquisition (DIA) methods that are available on most MS platforms, making the switch to HX-MS2 straightforward. Importantly, we find that HX-DIA enables …

Comparing Task Graph Scheduling Algorithms: An Adversarial Approach, Jared Coleman, Bhaskar Krishnamachari

Computer Science Faculty Works

Scheduling a task graph representing an application over a heterogeneous network of computers is a fundamental problem in distributed computing. It is known to be not only NP-hard but also not polynomial-time approximable within a constant factor. As a result, many heuristic algorithms have been proposed over the past few decades. Yet it remains largely unclear how these algorithms compare to each other in terms of the quality of schedules they produce. We identify gaps in the traditional benchmarking approach to comparing task scheduling algorithms and propose a simulated annealing-based adversarial analysis approach called PISA to help address them. We …