Digital Commons Network^™

The Stability Of Diazepam In Authentic Blood Samples From Thai Postmortem Cases, Peerayuht Phuangphung

Chulalongkorn Medical Journal

Background: Diazepam is a common drug detected in Thai postmortem cases. The stability of diazepam in blood was previously studied using spiked blood samples. However, there is no available data for stability in authentic postmortem blood samples.

Objectives: This study aims to determine the stability of diazepam in authentic postmortem blood samples.

Methods: Postmortem blood samples were obtained from the cadavers of Thai people who were sent for medico-legal autopsies at the Department of Forensic Medicine, Siriraj Hospital, Mahidol University. Blood samples were analyzed for diazepam and nordiazepam within one week after sample reception (initial concentrations: day_0). …

Investigating The Mass Mortality Induced Factors Of Pearl Oyster (Pinctada Radiata) At Abu Dhabi Pearls Farm, Uae, Hamad Ahmed Almansoori

Thesis/ Dissertation Defenses

The aquaculture of shellfish plays a crucial role in enhancing maritime environments by mitigating algal blooms and improving water quality through the filtration of organic matter, nutrients, and bacteria. This study investigated the environmental factors influencing oyster mortalities through a comprehensive analysis of water quality in Al Mirfa and Al Mughirah farming sites of Abu Dhabi (UAE), from February 2021 to February 2022. To reach such understanding of the main factors led to mass mortalities of cultivated oysters, different monthly sampling and both chemical and biological analyses of the farm water, sediments as well as for both living and dead …

Accuracy Of Nitrate Hysteresis And Flushing For Agricultural Watersheds In The Midwest, Noah Rudko, Sara K. W. Mcmillian, Jane Frankenberger, François Birgand

Graduate Industrial Research Symposium

Storm event-based metrics, such as hysteresis (HI) and flushing (FI), are used to differentiate nitrate pathways and sources, which is essential for watershed management. Estimations of these event-based metrics typically use high frequency (15-minute – hourly) measurements, but daily data are also used due to their greater availability. To date, there has been no study assessing how using lower frequency samples affect the accuracy of HI and FI, which could skew interpretation of potential nutrient pathways and sources. We used continuous measurements of nitrate collected at 9 watersheds throughout the Midwest spanning 448 storms. HI and FI were estimated from …

Measurement And Imaging Of Intra Matrix Igg Diffusion, Riya Debbarma, Antonio C. F. Dos Santos, Diana Milena Ramiez Gutierrez, Fernanda M. Da Cunha, Michael Ladisch

Graduate Industrial Research Symposium

Bovine IgG diffusion measurement by tracking the movement of the protein over time in an in-vitro matrix is motivated by the large number of protein/peptide therapeutics currently under various stages of development in the pharmaceutical industry. Many of these therapeutics are monoclonal antibodies (IgG type proteins) that are candidates for subcutaneous, intra-vitreous and intra-articular administration depending on the target of the therapeutic. Hyaluronic acid (HA) is a major constituent and determines the key attributes of the subcutaneous environment, vitreous humor of the eye and synovial fluid of the knee joint. HA exhibits varying molecular weight at these anatomic locations thereby …

Co-Crystallization Of Urea Granules For Slower Dissolution, Vidya Nagaraju, Carl Wassgren, Kingsly Ambrose

Graduate Industrial Research Symposium

Co-crystals are multicomponent crystals formed through hydrogen bond interactions. Co-crystallization, the process of developing cocrystals, serves as a versatile approach for discovering new solid forms of active ingredients (AIs) that can alter physical properties such as solubility, dissolution rates, and stability. These co-crystals can be produced through three main methods: solid-state methods, solution-based methods, and supercritical fluid methods. Recently, the solid-state (mechanochemical) method of developing cocrystals has gained more attention from researchers in the development of slow-release urea fertilizers. This technique can also be applied to the development of urease inhibitors. These multicomponent crystals present a potential solution to the …

Characterization Of Biological Particles Using An Integrated Hyperspectral Imaging And Machine Learning, Kaeul Lim, Arezoo Ardekani

Graduate Industrial Research Symposium

Hyperspectral imaging (HSI) is a promising modality in medicine with many potential applications. This study focuses on developing a label-free lipid nanoparticle characterization method using a convolutional neural network (CNN) analysis of HSI images. The HSI data, hypercube, consists of a series of images acquired at different wavelengths for the same field of view, providing continuous spectra information for each pixel. Three distinct liposome samples were collected for analysis. Advanced image preprocessing and classification methods for HSI data were developed to differentiate liposomes based on their material compositions. Our machine learning-based classification method was able to distinguish different liposome types …

Sustainable Water Treatment Systems In The La Vega Region Of The Dominican Republic, Hannah Fulton, Justina Thomae, Jorge Del Angel, Ramin Ansari, Karina Peate, Rylan Elliott, Adam Spieth, Thalia May, Morgan Jung, Ernest R. Blatchley Iii, Rebecca C. Johnson

Graduate Industrial Research Symposium

Purdue University's service-learning course, Water Supply in Developing Countries (WSDC) is dedicated to ensuring access to safe drinking water in the La Vega region of the Dominican Republic. The focus in the current academic year is to enhance the functionality, sustainability, and independence of community-based water treatment systems installed by previous WSDC students. Despite the construction of four water systems since 2012, operational challenges ensued, rendering them currently inoperable. Our objective is to learn from past mistakes, restore the systems and ensure their continuous functionality. During the fall semester, class members assessed repair needs in two communities with existing systems, …

Autonomous Roadside Mower Testing And Evaluation In Digital Twin Environments, Michael Mardikes, Ethan Brown, Timothy Wiegman, Nathan Sprague, Shreyas Supe, J. T. Evans

Graduate Industrial Research Symposium

Modern day roadside mowing operations in Indiana are performed by contractors operating tractors that pull flex-wing mowers. These mowing operations span over 11,000 miles of road across the state and create serious risk for human operators. Autonomous mowers can provide a safer alternative, but a replacement system must demonstrate an acceptable level of trust before large-scale deployment. A high-fidelity digital-twin environment can facilitate the capability to rapidly test and evaluate platforms in their desired application, while enabling zero real-world risk, a wide range of test variables, and repeatability of a test setup. The simulation environment must be at a level …

Mushrooom Production Without Solid Substrates, Alexander Baena, Marshall Porterfield

Graduate Industrial Research Symposium

Novel biotechnological approaches are needed to enhance renewable food production and waste recycling capabilities in resource-constrained environments. Edible mushrooms possess nutritious profiles and represent emerging opportunities to develop circular bioproduction by transforming waste organic materials into food and high-value products. However, traditional mushroom cultivation methods utilizing solid substrates have technical limitations like 1) uneven nutrient diffusion, 2) constant sterilization needs, 3) numerous intermediate steps that are energy and time-demanding, and 4) waste production from bags and jars. This work introduces an innovative hydroponic fungal cultivation system called Mycoponics™ using bioengineered ceramic materials. This liquid-nutrient-based technique optimizes fungal metabolism and facilitates …

A Machine Learning Model Of Perturb-Seq Data For Use In Space Flight Gene Expression Profile Analysis, Liam F. Johnson, James Casaletto, Lauren Sanders, Sylvain Costes

Graduate Industrial Research Symposium

The genetic perturbations caused by spaceflight on biological systems tend to have a system-wide effect which is often difficult to deconvolute it into individual signals with specific points of origin. Single cell multi-omic data can provide a profile of the perturbational effects, but does not necessarily indicate the initial point of interference within the network. The objective of this project is to take advantage of large scale and genome-wide perturbational datasets by using them to train a tuned machine learning model that is capable of predicting the effects of unseen perturbations in new data. Perturb-Seq datasets are large libraries of …

The Ethical Safeguards Within Servant Leadership, Jae Webb

Servant Leadership: Theory & Practice

Many of the prevailing strategies to address corporate misconduct are focused on an increase in regulation, greater oversight, and stricter punishments for offenders. Other strategies, often found in business schools, focus on developing cognitive moral reasoning skills. Both of these theories, by their nature, underestimate the power of context in ethical decision-making, as well as the importance of affirmative efforts to develop moral character. The following article explicates elements of servant-leadership theory that serve as ethical safeguards regarding a person’s ability to make ethical decisions, as well as aiding in the formation of contexts and cultures that facilitate ethical decision-making. …

Middle East, Kelly Blount, Howard L. Stovall, Mamoun Aidoud, Tania Tossa, Hassan Radhi, Noor Radhi, Nicolas Bremer, Joseph Busa Arop, Seyed Mohsen Rowhani, Jeremy Benjamin, Elad Sharabi, Sam Habbas, Ibrahim Sattout, Fouad Debs, Michela Cocchi, Ravinder Singh, Mansoor Malik, Khalid Rehman, Frank Lucente, Yessine Ferah, Anne Bodley

The Year in Review

No abstract provided.

International Animal Law, Frances Arricale, Daina Bray, Paula Cardoso, Matthew Collis, Giuliana D'Esopo, Erica Lyman, Jill Mariani, Omar Andrew Nimri, Megan O'Toole, Rajesh K. Reddy, Joan Schaffner, Fawn Schanz, Susan Schwartz, Malcolm Seheult

The Year in Review

No abstract provided.

Sexual Orientation And Gender Identity, Mark E. Wojcik

The Year in Review

No abstract provided.

Export Controls And Economic Sanctions, John Boscariol, Patrick Briscoe, Jamie Brown, Sylvia Costelloe, Abigail Cotterill, Geoffrey Goodale, Timothy O'Toole, Jason Prince, Christopher Stagg, Lawrence Ward

The Year in Review

No abstract provided.

Prevalence Of Small T Trauma In Depressed Adolescent And Early Adulthood Patient In King Chulalongkorn Memorial Hospital, Krittapast Thongrakyoo, Puchong Laurujisawat, Parichawan Chandarasiri

Chulalongkorn Medical Journal

Background: Trauma and depression are known to be related, especially in adolescents and early adulthood patients in which depression usually starts, then deteriorates, and causes decreased function and worse quality of life.

Objective: To study prevalence of small t trauma level in depressed adolescents and early adulthood patients and to study whether small t trauma level and severity of depression are related.

Methods: This cross-sectional descriptive study recruited depressive patients aged 15 – 25 years to complete a questionnaire consisted of 3 parts: demographic data and Big T trauma, BDI-IA scale Thai version, and the Small t trauma Level of …

Comparative Efficacy Of Topical Dimethicone And Permethrin For The Treatment Of Head Lice Infestation In Students, Behroz Davari, Somayeh Barik-Abi, Hassan Nasirian, Amir Hossein Zahirnia, Younes Mohammadi, Aref Salehzadeh

Chulalongkorn Medical Journal

Background: Despite improved living conditions, individual health and health indicators in human societies, head lice infestation continues to be a major health problem. Therefore, studying the efficacy of drugs and identifying treatment - resistant cases in the prevention and elimination of this disease is of particular importance.

Objective: The study aimed to determine the effectiveness of dimethicone and permethrin in infected pupils in elementary schools for girls.

Methods: This study was conducted on primary schoolgirls infected with head lice in Doroud County, Lorestan - Iran. The eighty infected girls were detected and randomized into two groups receiving any of the …

Depression, Smartphone Addiction And Association Factors Among Preclinical Medical Students, Aticha Wattanaudomchai

Chulalongkorn Medical Journal

Background: There were few studies of smartphone addiction behavior has been found in preclinical medical students.

Objective: To determine the prevalence and associated factors of depression of smartphone addiction behavior among preclinical medical students of Chulalongkorn University.

Methods: This is a cross-sectional descriptive study. The data were collected from preclinical medical students at Chulalongkorn University in 2020 academic year, prior to COVID-19 pandemic in Thailand. The instruments included the Smartphone Addiction Scale Thai version (SAS-SV-TH), Patient Health Questionnaire-9 Thai version (PHQ-9-T), Pittsburgh Sleep Quality Index Thai version (PSQI-T), and Thai Interpersonal questionnaire. The data were analyzed using SPSS version 25. …

Social Functioning And Associated Social Skills In Patients With Depressive Disorder In Psychiatric Outpatients, King Chulalongkorn Memorial Hospital, Peeraphon Lueboonthavatchai

Chulalongkorn Medical Journal

Background: Previous study have shown that 68.0% of patients with depressive disorder had social functioning impairment. The impaired social skills of these patients also affected the patients’ daily lives. However, there were limited studies concerning on social functioning, social skills and associated factors of patients with depressive disorder.

Objectives: This study aimed to investigate social functioning, social skills, and associated factors of patients with depressive disorder.

Methods: We recruited 150 patients from June to December 2019, aged above 18 years old, assessed: 1) Demographic data form; 2) Beck Depression Inventory-II (BDI-II) - Thai Version; 3) Social Skills Inventory; 4) Interpersonal …

Predictive Factors Of Success In The First Radioactive Iodine Treatment For Graves’ Disease, Pinyaporn On-Ekkasit

Chulalongkorn Medical Journal

Background: Initial treatment options for Graves’ disease are radioactive iodine (RAI) treatment, antithyroid drugs (ATDs), and surgery. RAI is effective and the definitive treatment for Graves’ disease.

Objective: To evaluate factors associated with success in the first RAI treatment for Graves’ disease.

Methods: A total of 89 patients who received the first RAI treatment for Graves’ disease between September 2016 and January 2021 were retrospectively reviewed. Thyroid function outcome was evaluated within one year after RAI treatment. Logistic regression analysis was performed to identify factors associated with success after RAI treatment.

Results: The success rate of the first RAI treatment …

درجة استخدام معلمي المرحلة الثانوية لاستراتيجيات التعليم الحديثة من وجهة نظر معلمي مدارس محافظة الكرك, Soumia Idmeithan Khalil Altarawneh

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدف المقال التعرف إلى درجة استخدام معلمي المرحلة الثانوية لاستراتيجيات التعليم الحديثة من وجهة نظر معلمي مدارس محافظة الكرك، وقد استخدمت الدراسة المنهج الوصفي التحليلي، وتم اختيار عينة الدراسة بالطريقة العشوائية، وبلغ قوامها (465) معلماً ومعلمة، تم توزيع استبانة الدراسة عليهم خلال الفصل الدراسي الأول من العام الدراسي 2022/2023. وتكونت الاستبانة من ثلاثة محاور (أهمية استراتيجيات التعليم الحديثة، استخدام استراتيجيات التعليم الحديثة، معوقات استخدام استراتيجيات التعليم الحديثة). وبعد إجراء اختبارات التحليل الإحصائي الملائمة لهذه الدراسة، توصلت الدراسة إلى أن وعي معلمي المرحلة الثانوية في مدارس محافظة الكرك بأهمية استراتيجيات التعليم الحديثة قد جاء بدرجة مرتفعة؛ بينما تطبيقهم لتلك الاستراتيجيات قد …

درجة امتلاك معلمات المرحلة الأساسية لعادات العقل في مدارس محافظة مادبا, Hanan Ahmad Mohammad Alhour

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدف المقال إلى معرفة درجة امتلاك معلمات المرحلة الأساسية لعادات العقل في مدارس محافظة مادبا، وقد تم استخدام الاستبانة كأداة للدراسة، ومجتمع الدراسة من معلمات المرحلة الأساسية في محافظة مأدبا، وبلغ عدد العينة (120) معلمة، وقد أظهرت نتائج الدراسة أن درجة امتلاك عادات العقل قد جاء بدرجة متوسطة، وقد أظهرت النتائج كذلك وجود فروق ذات دلالة إحصائية في درجة امتلاك معلمات المرحلة الأساسية لعادات العقل تعزى للمؤهل العلمي ولصالح من كانت مؤهلاتهم العلمية دراسات عليا، بينما أظهرت عدم وجود فروق ذات دلالة إحصائية تعزى لسنوات الخبرة، وقد أوصت الدراسة إلى ضرورة وضع البرامج التدريبية التي من شأنها تنمية عادات العقل …

Student Perspectives On Assignment Deadline Policies In Computer Science Courses, J. Kim, Christian Murphy

Computer Science Faculty Works

While the COVID-19 pandemic encouraged higher education to be more flexible, there is now growing uncertainty regarding the usefulness of flexibility as students return to in-person classes, particularly in fast-paced, rigorous fields such as Computer Science (CS). A big part of providing flexibility in education is through assignment deadlines. On one hand, flexible deadline policies may reduce student stress, help students face unexpected circumstances, and improve student learning; on the other, too much flexibility may lead to procrastination and poor time management. In order to help CS instructors make informed decisions when choosing an assignment deadline policy, we compared student …

Women's Reproductive Health: A Critical Appraisal Of Reproductive Justice And Magisterial Contributions To Responsible Family Planning, Kelly Olson

School of Theology and Seminary Graduate Papers/Theses

History reveals the degrading and traumatizing experiences of marginalized women harmed by unethical reproductive healthcare practices. Progress has been made; however divisive barriers still prohibit dialogue from resulting in a dignified approach to legislation that serves the diverse population of women in diverse situations of lived reality. Enhancing the theological dialogue with updated awareness of women’s reproductive healthcare needs and a renewed conversation of the benefit of expressed human sexuality in heterosexual marriage allows opportunity for the Magisterium to enhance teaching that aligns with Catholic tradition and grows with human understanding, in the spirit of aggiornamento. Improved clarity and wider …

Lsd To Galilee: Incarnation In The Psychedelic Subculture, Rob Zahn

Doctor of Ministry

This project is the result of a curiosity that there might be an opportunity (NPO) for the church, for everyone, to “learn how God is incarnate and works outside of the parameters of the church as evidenced by the birth of Contemporary Christian Music from the psychedelic hippie subculture of the late ’60s and early ’70s.” From a theological perspective, the answer might be obvious. Of course God is incarnate and works outside of any and all parameters humanity attempts to impose on the divine! However, what rises to the surface when such questions are engaged, is the extent to …

The Indiana Statesman, March 7, 2024, Indiana State University

Student Newspaper

Coby Clark wins national award; State DM raises over $15k to fight childhood cancer; Trump battles Supreme Court; Nikki Haley ends presidential campaign

Synthesis Of Current Evidence On Factors Influencing The Suitability Of Synthetic Biodegradable Mulches For Agricultural Applications: A Systematic Review, Michael Madin, Katherine Nelson, Kanji Fatema, Karina Schoengold, Abhilekha Dalal, Ikenna Onyekwelu, Rushrukh Rayan, Sanaz Saki Norouzi

Department of Agricultural Economics: Faculty Publications

Mulching practice offers farmers an opportunity to minimize the effects of drought, water loss, and soil erosion on crop production. Plastic film is widely used as a mulching material; however, contamination of arable lands by residual plastic has become a serious concern. Synthetic biodegradable mulch films and sprays may offer a more sustainable alternative to plastic films, however current evidence on the factors that influence the suitability of these products for agricultural applications is fragmented, making it unclear under what conditions these products meet agronomic, environmental, and societal needs. We address this gap by conducting a systematic review of studies …

From The Editor In Chief, Antulio J. Echevarria Ii

The US Army War College Quarterly: Parameters

Welcome to the Spring 2024 issue of Parameters. Readers will note a few differences in the formatting for this issue: we are now using endnotes instead of footnotes to facilitate switching from pdf to html via Adobe's Liquid App; also, readers will be able to click on each endnote number to view the full endnote and then switch back to the text to resume reading. Please drop us a note to let us know how you like the changes. More are coming!

Knowledge, Attitudes, And Beliefs Toward Third Hand Smoke, Gisele Tah

Walden Dissertations and Doctoral Studies

Third hand smoke (THS) is gaining significant interest in the environmental and public health fields as a new but dangerous phenomenon. THS is identified as a form of passive smoke consisting of residual nicotine and chemicals that settle on surfaces. THS is reported to be genotoxic in human cells, yet the public has limited or no knowledge of this new concept. The purpose of this qualitative, interpretive, descriptive study was to discover and describe the level of knowledge, attitudes, practices, and beliefs regarding THS among individuals in an eastern U.S. state. Social cognitive theory provided the theoretical framework for this …

Understanding Adherence To Prescribed Medical Regimen To Treat Hypertension Among African American Males, Yolanda Lucian George

Walden Dissertations and Doctoral Studies

Hypertension is referred to as the silent killer and has been for decades. African Americans have been affected disproportionately compared to Whites, leading to a significant medical and financial burden. The literature has demonstrated that even though African Americans have a similar or better awareness of hypertension, they are more likely to have poorer treatment outcomes and have their hypertension less controlled. In this study, the health belief model and the ecological social model were used as the guiding framework to understand this phenomenon. In this qualitative study, semistructured interviews were used to explore and understand the perception of adherence …