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Articles 78511 - 78540 of 818004
Full-Text Articles in Entire DC Network
Preparation And Quality Evaluation Of Polygonati Rhizoma Modified Powder By Extrusion Cooking, Cao Yuxin, Zheng Tao, Luo Kun, Zheng Hui, Yang Yong
Preparation And Quality Evaluation Of Polygonati Rhizoma Modified Powder By Extrusion Cooking, Cao Yuxin, Zheng Tao, Luo Kun, Zheng Hui, Yang Yong
Food and Machinery
Objective: This study aimed to improve the functional characteristics of Polygonati rhizoma (PR). Methods: Using the freeze-dried fresh PR and nine-steam-nine-bask processing PR as control products, the study comprehensively compared and analyzed human sensory, electronic sensory, color, fluidity, dissolving ability, extract content, total polysaccharide content and total saponin content in PR powder modified by extrusion cooking. Results: Extrusion cooking effectively eliminated the bad taste and improved the color and fluidity of PR powder. Compared with the nine-steam-nine-bask processing, extrusion cooking significantly increased the total polysaccharide content and total saponin content, with increase rates of 49.27% and 69.10%, respectively. Conclusion: …
Optimization Of Pectin Extraction From Immature Fruits Of Guanxi Pomelo By Lactobacillus Plantarum Fermentation, Ding Hongxia, Yang Yuanfan, Huang Shuan, Ni Hui
Optimization Of Pectin Extraction From Immature Fruits Of Guanxi Pomelo By Lactobacillus Plantarum Fermentation, Ding Hongxia, Yang Yuanfan, Huang Shuan, Ni Hui
Food and Machinery
Objective: This study aimed to optimize the pectin extraction yield from immature fruits of Guanxi pomelo by L. plantarum fermentation and analysis of the properties of pectin extracted by L.s plantarum fermentation. Methods: Taking the extraction yield of pectin as the index, orthogonal test was used to optimize the process conditions of fermentation of immature fruits of Guanxi pomelo by L. plantarum, and the content of galacturonic acid, degree of esterification, protein, water-holding capacity, oil-holding capacity, emulsifying activity and emulsion stability of pectin were determined. Results: The optimal conditions for fermentation of immature fruits of Guanxi pomelo by L. …
Research Progress On Extraction, Structural, Functional Properties And Applications Of Tuber Polysaccharides, Li Pan, Zeng Xiangquan, Li Qianqian, Li Jian
Research Progress On Extraction, Structural, Functional Properties And Applications Of Tuber Polysaccharides, Li Pan, Zeng Xiangquan, Li Qianqian, Li Jian
Food and Machinery
Polysaccharides are the main active ingredients of edible fungi, which have been widely utilized in the food industry. As a member of the truffle family, Tuber are rich in polysaccharides. Previous studies mainly focused on solvent, ultrasound-assisted, microwave-assisted, enzyme-assisted and pressurized liquid extractions regarding the extraction methods of Tuber polysaccharides. The molecular weight, monosaccharide composition and content, configuration, and ligation mechanism of sugar residues, along with the polysaccharide types of Tuber polysaccharides, have all been studied in relation to the characterization of chemical structures. Additionally, the antioxidant, antitumor, hypoglycemia, anti-fatigue, and immunomodulatory activities have been evaluated as well. In food …
Applications Of Modified Dietary Fibers In Flour Products, Pei Lina, Luo Denglin, Li Peiyan, Yue Chonghui, Bai Zhouya
Applications Of Modified Dietary Fibers In Flour Products, Pei Lina, Luo Denglin, Li Peiyan, Yue Chonghui, Bai Zhouya
Food and Machinery
Flour loses a large amount of dietary fiber (DF) during precision processing, which is considered an important component of a healthy diet and has various physiological activities. This review introduces the common modification methods of DF and summarizes the change rules and reasons of physical and chemical properties and physiological activities of DF after modification. Additionally, the applications of DF in dough, biscuits, noodles, bread, steamed bread and cakes are discussed. The current issues and potential future development paths are also highlighted.
Research Progress Of Mung Bean Pre-Curing Technology And Quality, Qu Meilin, Hu Junjun, Cheng Zhe, Li Yunlong
Research Progress Of Mung Bean Pre-Curing Technology And Quality, Qu Meilin, Hu Junjun, Cheng Zhe, Li Yunlong
Food and Machinery
Mung beans are rich in nutrients, but their dense structure and dense cortex lead to long a maturation time and poor edible convenience. To provide an empirical basis and novel ideas for future research on the pre-ripening of mung beans, this review analyzes pre-ripening, specifically focusing on the pre-ripening process of mung beans and the effects of different processing methods on the edible quality and nutritional components of mung beans. Moreover, the development direction of preripening technology of mung beans is also prospected.
Species Abundance Modelling Of Arctic-Boreal Zone Ducks Informed By Satellite Remote Sensing, Michael Allan Merchant, Michael Battaglia, Nancy H. French, Kevin Smith, Howard V. Singer, Llwellyn Armstrong, Vanessa B. Harriman, Stuart Slattery
Species Abundance Modelling Of Arctic-Boreal Zone Ducks Informed By Satellite Remote Sensing, Michael Allan Merchant, Michael Battaglia, Nancy H. French, Kevin Smith, Howard V. Singer, Llwellyn Armstrong, Vanessa B. Harriman, Stuart Slattery
Michigan Tech Publications
The Arctic-Boreal zone (ABZ) covers over 26 million km2 and is home to numerous duck species; however, understanding the spatiotemporal distribution of their populations across this vast landscape is challenging, in part due to extent and data scarcity. Species abundance models for ducks in the ABZ commonly use static (time invariant) habitat covariates to inform predictions, such as wetland type and extent maps. For the first time in this region, we developed species abundance models using high-resolution, time-varying wetland inundation data produced using satellite remote sensing methods. This data captured metrics of surface water extent and inundated vegetation in the …
Transcendence, A.I. & Hybrid Humans, The Philosophical Discussion Group
Transcendence, A.I. & Hybrid Humans, The Philosophical Discussion Group
The Philosopher's Stone
No abstract provided.
Assessing Beef Producers' Interest In Cooperative Business Models In New Hampshire, Maine, And Vermont, E M. Enzien, Peter S. Erickson, Analena B. Bruce, C W. Knight, Andrew B. Conroy
Assessing Beef Producers' Interest In Cooperative Business Models In New Hampshire, Maine, And Vermont, E M. Enzien, Peter S. Erickson, Analena B. Bruce, C W. Knight, Andrew B. Conroy
Faculty Publications
This study assessed the characteristics of northern New England producers and their willingness to participate in cooperative marketing (CM) or cooperative processing (CoP) of beef cattle. A survey was conducted with producers in the region. Pearson correlation coeffi- cients were used to evaluate whether producers were will- ing to participate in CM or CoP. Two multiple regression models were created using variance inflation procedures and backward elimination to predict whether producers were likely to participate in CM and CoP. A total of 174 surveys were returned and 161 were usable for analysis. Producers in- terested in CoP were likely also …
Reassignment Of A Junior Synonym Of Lepisosteus Oculatus Winchell 1864 To L. Platostomus Rafinesque 1820, Daniel Sinopoli, Thomas J. Near, Solomon R. David, Prosanta Chakrabarty
Reassignment Of A Junior Synonym Of Lepisosteus Oculatus Winchell 1864 To L. Platostomus Rafinesque 1820, Daniel Sinopoli, Thomas J. Near, Solomon R. David, Prosanta Chakrabarty
Faculty Publications
The foundation for the current taxonomy of Lepisosteidae (gars) was laid by Suttkus (1963) and Wiley (1976); these authors recognized only two extant genera as valid, Lepisosteus and Atractosteus. These authors also only recognized seven living species of gars and assigned several previously recognized species as junior synonyms. One of these, Lepisosteus oculatus Winchell 1864 possesses five junior synonyms: Cylindrosteus latirostris Girard 1858, Cylindrosteus productus Cope 1865, Cylindrosteus agassizii Duméril 1870, Cylindrosteus zadockii Duméril 1870 and Cylindrosteus bartonii Duméril 1870. Cylindrosteus zadockii was described from two syntypes collected from the “Upper Mississippi River” (MHNH 5799, 5800; Figure 1), and was …
Eurasian Aspen (Populus Tremula L.): Central Europe's Keystone Species 'Hiding In Plain Sight', Antonín Kusbach, Jan Šebesta, Robert Hruban, Pavel Peška, Paul C. Rogers
Eurasian Aspen (Populus Tremula L.): Central Europe's Keystone Species 'Hiding In Plain Sight', Antonín Kusbach, Jan Šebesta, Robert Hruban, Pavel Peška, Paul C. Rogers
Aspen Bibliography
Knowledge of Eurasian aspen’s (Populus tremula L.) ecological and growth characteristics is of high importance to plant and wildlife community ecology, and noncommercial forest ecosystem services. This research assessed these characteristics, identified aspen’s habitat optimum, and examined causality of its current scarce distribution in central Europe. We analyzed a robust database of field measurements (4,656,130 stands) for forest management planning over 78,000 km2 of the Czech territory. Our analysis we used GIS techniques, with basic and multivariate statistics such as general linear models, ordination, and classification. Results describe a species of broad ecological amplitude that has heretofore attracted …
The Lumberjack, March 27, 2024
The Lumberjack, March 27, 2024
Cal Poly Humboldt's Student Newspaper
The student newspaper of Humboldt State University.
Phylogenomics Of Tetraopes Longhorn Beetles Unravels Their Evolutionary History And Biogeographic Origins, Nayeli Gutiérrez‑Trejo, Matthew H. Van Dam, Athena W. Lam, Gonzalo Martínez‑Herrera, Felipe A. Noguera, Thomas J. Weissling, Jessica L. Ware, Víctor H. Toledo‑Hernández, Frederick W. Skillman Jr., Brian D. Farrell, Oscar Pérez‑Flores, Lorenzo Prendini, James M. Carpenter
Phylogenomics Of Tetraopes Longhorn Beetles Unravels Their Evolutionary History And Biogeographic Origins, Nayeli Gutiérrez‑Trejo, Matthew H. Van Dam, Athena W. Lam, Gonzalo Martínez‑Herrera, Felipe A. Noguera, Thomas J. Weissling, Jessica L. Ware, Víctor H. Toledo‑Hernández, Frederick W. Skillman Jr., Brian D. Farrell, Oscar Pérez‑Flores, Lorenzo Prendini, James M. Carpenter
Department of Entomology: Faculty Publications
Tetraopes longhorn beetles are known for their resistance to milkweed plant toxins and their coevolutionary dynamics with milkweed plants (Asclepias). This association is considered a textbook example of coevolution, in which each species of Tetraopes is specialized to feed on one or a few species of Asclepias. A major challenge to investigating coevolutionary hypotheses and conducting molecular ecology studies lies in the limited understanding of the evolutionary history and biogeographical patterns of Tetraopes. By integrating genomic, morphological, paleontological, and geographical data, we present a robust phylogeny of Tetraopes and their relatives, using three inference methods with …
Hurricane Impacts On Water Resources: A Look At Nature-Based Solutions To Improve Long-Term Resilience, Fautemeh Sajadi Bami
Hurricane Impacts On Water Resources: A Look At Nature-Based Solutions To Improve Long-Term Resilience, Fautemeh Sajadi Bami
USF Tampa Graduate Theses and Dissertations
Severe storms are a common occurrence in the state of Florida. Hurricane events may cause hazards such as flooding, property damage, death, and many others. Such far-reaching impacts may potentially result in dangerous consequences where they occur. Of interest to this study were the impacts on water resources and water quality caused by storms. Hurricanes can bring about a deluge. An apparent excess of water may cause the notion of water scarcity to seem less significant. However, problems with potable water can be quite frequent due to storms.
This research sought to address the impacts of severe storms on water …
Prescribed Fire Effects On Microbial Communities And Functions In Managed Ecosystems, Viet Dao
Prescribed Fire Effects On Microbial Communities And Functions In Managed Ecosystems, Viet Dao
LSU Doctoral Dissertations
Microbes (both fungi and bacteria) serve important ecosystem functional roles in nutrient cycling and decomposition, which affect ecosystem response following disturbances such as prescribed fire. A multitude of abiotic and biotic factors influence microbial community compositions, which then drive microbial ecosystem functions. The factors driving microbial communities further change due to fire disturbances and progression with time. Although prescribed fire is commonly used as a technique for ecosystem management, the effects of fire on microbial communities or their functions are simply understudied. Ecosystem management decisions tend to focus on plant and ecosystem post-fire responses. Thus, incorporation of fire effects on …
The American View On Global Education In Curriculum And Its Necessity For Entering The Workforce, Alison Taylor
The American View On Global Education In Curriculum And Its Necessity For Entering The Workforce, Alison Taylor
Student Theses and Dissertations
The problem addressed in this study is the lack of globalization terminology and geography standards included in the United States’ public education system leading to a workforce that is missing key 21st century skill competency. According to social efficiency theory, it is important for education to teach the necessary employability skills in the school curriculum. Geography standards align with employability skills, but the subject is disappearing from United States classrooms. This quantitative regression study evaluates the predictive relationships between exposure to geography curriculum in the United States, American perception of the importance of geography, and recent high school graduate’s self-assessed …
The Effects Of Genetic And Modifiable Risk Factors On Brain Regions Vulnerable To Ageing And Disease, Jordi Manuello, Joosung Min, Paul Mccarthy, Fidel Alfaro-Almagro, Soojin Lee, Stephen Smith, Lloyd T. Elliott, Anderson M. Winkler, Gwenaëlle Douaud
The Effects Of Genetic And Modifiable Risk Factors On Brain Regions Vulnerable To Ageing And Disease, Jordi Manuello, Joosung Min, Paul Mccarthy, Fidel Alfaro-Almagro, Soojin Lee, Stephen Smith, Lloyd T. Elliott, Anderson M. Winkler, Gwenaëlle Douaud
School of Medicine Publications
We have previously identified a network of higher-order brain regions particularly vulnerable to the ageing process, schizophrenia and Alzheimer’s disease. However, it remains unknown what the genetic influences on this fragile brain network are, and whether it can be altered by the most common modifiable risk factors for dementia. Here, in ~40,000 UK Biobank participants, we first show significant genome-wide associations between this brain network and seven genetic clusters implicated in cardiovascular deaths, schizophrenia, Alzheimer’s and Parkinson’s disease, and with the two antigens of the XG blood group located in the pseudoautosomal region of the sex chromosomes. We further reveal …
S100a8/A9 As A Prognostic Biomarker With Causal Effects For Post-Acute Myocardial Infarction Heart Failure, Jie Ma, Yang Li, Ping Li, Xinying Yang, Shuolin Zhu, Ke Ma, Fei Gao, Hai Gao, Hui Zhang, Xin-Liang Ma, Jie Du, Yulin Li
S100a8/A9 As A Prognostic Biomarker With Causal Effects For Post-Acute Myocardial Infarction Heart Failure, Jie Ma, Yang Li, Ping Li, Xinying Yang, Shuolin Zhu, Ke Ma, Fei Gao, Hai Gao, Hui Zhang, Xin-Liang Ma, Jie Du, Yulin Li
Department of Emergency Medicine Faculty Papers
Heart failure is the prevalent complication of acute myocardial infarction. We aim to identify a biomarker for heart failure post-acute myocardial infarction. This observational study includes 1062 and 1043 patients with acute myocardial infarction in the discovery and validation cohorts, respectively. The outcomes are in-hospital and long-term heart failure events. S100A8/A9 is screened out through proteomic analysis, and elevated circulating S100A8/A9 is independently associated with heart failure in discovery and validation cohorts. Furthermore, the predictive value of S100A8/A9 is superior to the traditional biomarkers, and the addition of S100A8/A9 improves the risk estimation using traditional risk factors. We finally report …
Toxicity Of Three Species Of The Solanaceae Family Growing In Algeria Against Culiseta Longiareolata Mosquitos 4th Stage Larvae, Saliha Benhissen, Abdelmaddjid Yagoub Asloum, Nora Belkhiri, Zakaria Hedjouli, Siham Bounadji, Wafa Habbachi, Khellaf Rebbas
Toxicity Of Three Species Of The Solanaceae Family Growing In Algeria Against Culiseta Longiareolata Mosquitos 4th Stage Larvae, Saliha Benhissen, Abdelmaddjid Yagoub Asloum, Nora Belkhiri, Zakaria Hedjouli, Siham Bounadji, Wafa Habbachi, Khellaf Rebbas
Journal of Bioresource Management
Mosquitoes have always been considered a source of harm to humans and animals mainly because they can be vectors of disease. This work represents a study on the effect of aqueous extract of three plants (Hyoscyamus albus, Solanum elaeagnifolium, Solanum nigrum) of the Solanaceae family on the mortality of 4th stage larvae of Culiseta longiareolata larvae. Extract of the high impact is of S. nigrum followed by H. albus and S. elaeagnifolium, respectivley of C. longiareolata larvae.
Green Synthesis Of Zinc Oxide Nanoparticles From Althaea Officinalis Flower Extract Coated With Chitosan For Potential Healing Effects On Diabetic Wounds By Inhibiting Tnf-Α And Il-6/Il-1Β Signaling Pathways, Sammar F. Elhabal, Nashwa Abdelaal, Saeed A.K.S. Al-Zuhairy, Mohamed F. Mohamed Elrefai, Ahmed M.E. Hamdan, Mohamed M. Khalifa, Sandra Hababeh, Mohammad A. Khasawneh, Gehad M. Khamis, Jakline Nelson, Passant M. Mohie, Rania A. Gad, Amira Rizk, Soad L. Kabil, Mohamed K. El-Ashery, Bhaskara R. Jasti, Nahla A. Elzohairy, Tayseer Elnawawy, Fatma E. Hassan, Mohamed A. El-Nabarawi
Green Synthesis Of Zinc Oxide Nanoparticles From Althaea Officinalis Flower Extract Coated With Chitosan For Potential Healing Effects On Diabetic Wounds By Inhibiting Tnf-Α And Il-6/Il-1Β Signaling Pathways, Sammar F. Elhabal, Nashwa Abdelaal, Saeed A.K.S. Al-Zuhairy, Mohamed F. Mohamed Elrefai, Ahmed M.E. Hamdan, Mohamed M. Khalifa, Sandra Hababeh, Mohammad A. Khasawneh, Gehad M. Khamis, Jakline Nelson, Passant M. Mohie, Rania A. Gad, Amira Rizk, Soad L. Kabil, Mohamed K. El-Ashery, Bhaskara R. Jasti, Nahla A. Elzohairy, Tayseer Elnawawy, Fatma E. Hassan, Mohamed A. El-Nabarawi
Pacific Faculty Work
Background: Diabetes Mellitus is a multisystem chronic pandemic, wound inflammation, and healing are still major issues for diabetic patients who may suffer from ulcers, gangrene, and other wounds from uncontrolled chronic hyperglycemia. Marshmallows or Althaea officinalis (A.O.) contain bioactive compounds such as flavonoids and phenolics that support wound healing via antioxidant, anti-inflammatory, and antibacterial properties. Our study aimed to develop a combination of eco-friendly formulations of green synthesis of ZnO-NPs by Althaea officinalis extract and further incorporate them into 2% chitosan (CS) gel. Method and Results: First, develop eco-friendly green Zinc Oxide Nanoparticles (ZnO-NPs) and incorporate them into a 2% …
Effects Of Sodium Isoascorbate Treatment On Storage Quality Of Fresh-Cut Lanzhou Lily, Xiong Siguo, Tang Xiaolan, Song Longlong, Pan Xuan, Ge Junqiao, Jiang Aili
Effects Of Sodium Isoascorbate Treatment On Storage Quality Of Fresh-Cut Lanzhou Lily, Xiong Siguo, Tang Xiaolan, Song Longlong, Pan Xuan, Ge Junqiao, Jiang Aili
Food and Machinery
Objective: This study aimed to extend the storage period of fresh-cut Lanzhou lily. Methods: Fresh-cut Lanzhou lily was used as raw materials. Following fresh-cut processing, the raw materials were soaked with 0 (CK), 1, 5, and 10 g/L of SI solution to analyze the quality changes of fresh-cut Lanzhou lily during storage. Results: The soaking treatment with 10 g/L of SI could better maintain the brightness of freshly cut Lanzhou lily. At 21 days of storage, the concentrations of malondialdehyde, soluble sugar, and browning were, respectively, 45%, 8%, and 23% lower than those of the CK group. The SI-treated group …
Study On Process Optimization And Antioxidant Activity Of Fermentative Cynanchum Auriculatum Tablet, Bu Jing, Shi Yun, Lin Yan, Qin Yuanyuan, Hong Jian
Study On Process Optimization And Antioxidant Activity Of Fermentative Cynanchum Auriculatum Tablet, Bu Jing, Shi Yun, Lin Yan, Qin Yuanyuan, Hong Jian
Food and Machinery
Objective: This study aimed to optimize the process parameters of fermentative Cynanchum auriculatum (CA) tablets to develop a new type of fermented product of CA. Methods: Taking complete slices of CA as raw materials, the process parameters of fermentative CA tablets were optimized by response surface methodology based on single factor experiments with sensory score and total acid content as indicators, and the antioxidant activity and amino acid content of fermentative CA tablets were tested. Results: The optimal process parameters for fermentative CA tablets were material liquid at ratio 1∶1, fermentation at 31 ℃, inoculation amount 9.6% and fermenting for …
Fair Header Reference Genome: A Trustworthy Standard, Adam Wright, Mark D Wilkinson, Christopher Mungall, Scott Cain, Stephen Richards, Paul Sternberg, Ellen Provin, Jonathan L Jacobs, Scott Geib, Daniela Raciti, Karen Yook, Lincoln Stein, David C Molik
Fair Header Reference Genome: A Trustworthy Standard, Adam Wright, Mark D Wilkinson, Christopher Mungall, Scott Cain, Stephen Richards, Paul Sternberg, Ellen Provin, Jonathan L Jacobs, Scott Geib, Daniela Raciti, Karen Yook, Lincoln Stein, David C Molik
Faculty, Staff and Students Publications
The lack of interoperable data standards among reference genome data-sharing platforms inhibits cross-platform analysis while increasing the risk of data provenance loss. Here, we describe the FAIR bioHeaders Reference genome (FHR), a metadata standard guided by the principles of Findability, Accessibility, Interoperability and Reuse (FAIR) in addition to the principles of Transparency, Responsibility, User focus, Sustainability and Technology. The objective of FHR is to provide an extensive set of data serialisation methods and minimum data field requirements while still maintaining extensibility, flexibility and expressivity in an increasingly decentralised genomic data ecosystem. The effort needed to implement FHR is low; FHR's …
Affinity-Tagged Smad1 And Smad5 Mouse Lines Reveal Transcriptional Reprogramming Mechanisms During Early Pregnancy, Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin Matzuk
Affinity-Tagged Smad1 And Smad5 Mouse Lines Reveal Transcriptional Reprogramming Mechanisms During Early Pregnancy, Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin Matzuk
Faculty, Staff and Students Publications
Endometrial decidualization, a prerequisite for successful pregnancies, relies on transcriptional reprogramming driven by progesterone receptor (PR) and bone morphogenetic protein (BMP)-SMAD1/SMAD5 signaling pathways. Despite their critical roles in early pregnancy, how these pathways intersect in reprogramming the endometrium into a receptive state remains unclear. To define how SMAD1 and/or SMAD5 integrate BMP signaling in the uterus during early pregnancy, we generated two novel transgenic mouse lines with affinity tags inserted into the endogenous SMAD1 and SMAD5 loci (Smad1HA/HA and Smad5PA/PA). By profiling the genome-wide distribution of SMAD1, SMAD5, and PR in the mouse uterus, we demonstrated …
Advancing Access To Genome Sequencing For Rare Genetic Disorders: Recent Progress And Call To Action, Vaidehi Jobanputra, Brock Schroeder, Heidi L Rehm, Wei Shen, Elizabeth Spiteri, Ghunwa Nakouzi, Stacie Taylor, Christian R Marshall, Linyan Meng, Stephen F Kingsmore, Katarzyna Ellsworth, Euan Ashley, Ryan J Taft, Medical Genome Initiative
Advancing Access To Genome Sequencing For Rare Genetic Disorders: Recent Progress And Call To Action, Vaidehi Jobanputra, Brock Schroeder, Heidi L Rehm, Wei Shen, Elizabeth Spiteri, Ghunwa Nakouzi, Stacie Taylor, Christian R Marshall, Linyan Meng, Stephen F Kingsmore, Katarzyna Ellsworth, Euan Ashley, Ryan J Taft, Medical Genome Initiative
Faculty, Staff and Students Publications
No abstract provided.
Sex-Based Differences In Melanoma Survival Improvement From 2004 To 2018, Vikram R Shaw, Angela Hudock, Baoyi Zhang, Christopher Amos, Chao Cheng
Sex-Based Differences In Melanoma Survival Improvement From 2004 To 2018, Vikram R Shaw, Angela Hudock, Baoyi Zhang, Christopher Amos, Chao Cheng
Faculty, Staff and Students Publications
Simple Summary
Melanoma is the deadliest form of skin cancer and its incidence and mortality may vary by demographic factors, such as sex, age, race, and socioeconomic status. Few studies, however, have characterized disparities in survival improvement across these demographic groups in melanoma. In the present study, the authors highlight disparities in melanoma survival improvement, both in diagnosed melanoma and carcinoma in situ. While melanoma survival has improved overall, some patient subgroups have experienced a lower improvement in survival from 2004 to 2018.
Abstract
Background: Melanoma is the deadliest form of skin cancer and its incidence and mortality vary by …
Identification Of An Early Survival Prognostic Gene Signature For Localized Osteosarcoma Patients, Tajhal D Patel, Sandra L Grimm, Rupa S Kanchi, Tanmay Gandhi, Amrit Koirala, Jason T Yustein, Cristian Coarfa
Identification Of An Early Survival Prognostic Gene Signature For Localized Osteosarcoma Patients, Tajhal D Patel, Sandra L Grimm, Rupa S Kanchi, Tanmay Gandhi, Amrit Koirala, Jason T Yustein, Cristian Coarfa
Faculty, Staff and Students Publications
Osteosarcoma is the most prevalent bone tumor in pediatric patients. Neoadjuvant chemotherapy has improved osteosarcoma patient survival, however the 5-year survival rate for localized osteosarcoma is 75% with a 30-50% recurrence rate. We, therefore, sought to identify a prognostic gene signature which could predict poor prognosis in localized osteosarcoma patients. Using the TARGET osteosarcoma transcriptomic dataset, we identified a 13-hub gene signature associated with overall survival and time to death of localized osteosarcoma patients, with the high-risk group showing a 22% and the low-risk group showing 100% overall survival. Furthermore, network analysis identified five modules of co-expressed genes that significantly …
Dynamic Fibrillar Assembly Of Αb-Crystallin Induced By Perturbation Of The Conserved Nt-Ixi Motif Resolved By Cryo-Em, Russell Mcfarland, Steve Reichow
Dynamic Fibrillar Assembly Of Αb-Crystallin Induced By Perturbation Of The Conserved Nt-Ixi Motif Resolved By Cryo-Em, Russell Mcfarland, Steve Reichow
Chemistry Faculty Publications and Presentations
αB-crystallin is an archetypical member of the small heat-shock proteins (sHSPs) vital for cellular proteostasis and mitigating protein misfolding diseases. Gaining insights into the principles defining their molecular organization and chaperone function have been hindered by intrinsic dynamic properties and limited high-resolution structural analysis. To disentangle the mechanistic underpinnings of these dynamical properties, we mutated a conserved IXI-motif located within the N-terminal (NT) domain of human αB-crystallin. This resulted in a profound structural transformation, from highly polydispersed caged-like native assemblies into a comparatively well-ordered helical fibril state amenable to high-resolution cryo-EM analysis. The reversible nature of the induced fibrils facilitated …
Study Protocol: Identifying Transcriptional Regulatory Alterations Of Chronic Effects Of Blast And Disturbed Sleep In United States Veterans, Molly J. Sullan, Kelly A. Stearns-Yoder, Zhaoyu Wang, Andrew J. Hoisington, Adam D. Brenoweth, Walter Carr, Yongchao Ge, Hanga Galfalvy, Fatemah Haghighi, Lisa A. Brenner
Study Protocol: Identifying Transcriptional Regulatory Alterations Of Chronic Effects Of Blast And Disturbed Sleep In United States Veterans, Molly J. Sullan, Kelly A. Stearns-Yoder, Zhaoyu Wang, Andrew J. Hoisington, Adam D. Brenoweth, Walter Carr, Yongchao Ge, Hanga Galfalvy, Fatemah Haghighi, Lisa A. Brenner
Faculty Publications
Injury related to blast exposure dramatically rose during post-911 era military conflicts in Iraq and Afghanistan. Mild traumatic brain injury (mTBI) is among the most common injuries following blast, an exposure that may not result in a definitive physiologic marker (e.g., loss of consciousness). Recent research suggests that exposure to low level blasts and, more specifically repetitive blast exposure (RBE), which may be subconcussive in nature, may also impact long term physiologic and psychological outcomes, though findings have been mixed. For military personnel, blast-related injuries often occur in chaotic settings (e.g., combat), which create challenges in the immediate assessment of …
School Teachers' Perceptions Of Adolescent Human Papillomavirus (Hpv) Vaccination: A Systematic Review, Jihye Choi, Efrat K Gabay, Paula M Cuccaro
School Teachers' Perceptions Of Adolescent Human Papillomavirus (Hpv) Vaccination: A Systematic Review, Jihye Choi, Efrat K Gabay, Paula M Cuccaro
Faculty, Staff and Student Publications
School nurses are uniquely positioned to educate students about immunizations, including human papillomavirus (HPV) vaccination, but schools are often without a nurse for different reasons. In lieu of nurses, teachers who closely interact with students and are traditionally well-trusted by parents may be able to communicate about HPV vaccination, alleviating parental vaccine hesitancy. This systematic review explores school teachers' perspectives on adolescent HPV vaccination and factors influencing their willingness to make vaccine recommendations. We searched three databases with appropriate medical subject headings and keywords to identify relevant studies. We reviewed fifteen studies and provided an extensive summary and a comparison …