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Flood Waters Rise: Hurricanes, Disaster Response, And Race Relations In Coastal Alabama, 1906 – 2006, Danielle Leonardi

Graduate Theses and Dissertations (2019 - present)

This thesis examines the changes in social relations after natural disasters, specifically hurricanes. The Hurricane of 1906 caused massive damage to Mobile due to the limited warnings. Tensions before the hurricane were already heightened from the Atlanta Race Riot and boiled over after the storm, resulting in a double lynching. Mobile received very little federal aid after the 1906 hurricane and relief heavily on their own communities and the Alabama National Guard. Hurricane Frederic in 1979 was much different because of its position in the Civil Rights Movement. The government relief was slow due to the overwhelming amount needed, and …

Sex And Age Differences In Near-Infrared Spectroscopy Responses And The Resulting Influences On Cognition, Miranda K. Traylor

Graduate Theses and Dissertations (2019 - present)

Vascular dysfunction is the earliest known marker of neurodegeneration. However, limited research has been conducted to determine if changes in peripheral vascular function track differences in brain health. Therefore, the purpose was to determine if previously reported sex differences in near-infrared spectroscopy (NIRS) vascular occlusion test (VOT) parameters persist across the lifespan and if these differences track age- and sex-related differences in a cognitive task. Ninety-nine healthy, cognitively intact adults (50 women, 49 men) across the adult lifespan (19-81 yrs) were used for analysis. The combination of NIRS-VOT was used to quantify microvascular function. Cognition was defined as the time …

Presence Of Nematodes In Gopherus Polyphemus In The Abacoa Greenway, Leighton Stack

Harriet L Wilkes Honors College Theses

Endo-parasitic nematodes infect the gastrointestinal tract of their reptile hosts including the Gopher polyphemus species. Gopher tortoises are a keystone species that are recognized as a threatened species in Florida. The health of the gopher tortoises is negatively affected by these parasites that cause a plethora of diseases and symptoms. Convenience sampling was used to collect fecal samples from tortoises of the Abacoa Greenway over the past two years. PCR amplified isolated DNA from the fecal samples for a consensus sequence of the nematode 18S rRNA gene. Visualization of the PCR reactions via gel electrophoresis revealed amplification of the appropriately …

Original Public Meaning And Pregnancy’S Ambiguities, Evan D. Bernick, Jill Wieber Lens

Michigan Law Review

Relying on 1868 abortion statutes, the 2022 Supreme Court held in Dobbs v. Jackson Women’s Health Organization that no federal constitutional right to abortion exists. Mere months later, a petition for certiorari asked the Court to determine that “person” in the Fourteenth Amendment includes prenatal existence, which would require criminalization of abortion in all states. The petitioners cited Dobbs and claimed the authority of legal history in 1868 and before. These arguments will be heard again, and they are increasingly framed in terms of the “original public meaning” of the Fourteenth Amendment.

This Article refutes these arguments on their own …

Endo/Exo, Delaney Rogers

Electronic Theses and Dissertations

The artist, Delaney Shae Rogers, discusses her Master of Fine Arts exhibition, Endo / Exo, held at the Tipton Gallery in downtown Johnson City, TN. The exhibition dates are from March 25th through April 5th, 2024, with a public reception held April 5th, 2024. The author provides insight into the concept behind the work in the exhibition and shares how the making process and specific materials impact the work. This body of work explores coping with grief, anxiety, and the state of the world through the process of making and communicating otherwise difficult topics through visually digestible symbolic language.

Early Life Cardiovascular Risk Factors And Midlife Epigenetic Aging: An Enduring Legacy, Paul S De Vries, Anthony S Zannas

Faculty, Staff and Student Publications

No abstract provided.

Disaster Plant Pathology: Smart Solutions For Threats To Global Plant Health From Natural And Human-Driven Disasters, Berea A. Etherton, Robin A. Choudhury, Ricardo I. Alcalá Briseño, Romaric A. Mouafo-Tchinda, Aaron I. Plex Sulá, Manoj Choudhury, Ashish Adhikari, Si Lin Lei, Nattapol Kraisitudomsook, Jacobo Robledo Buritica

School of Earth, Environmental, & Marine Sciences Faculty Publications

Disaster plant pathology addresses how natural and human-driven disasters impact plant diseases, and the requirements for smart management solutions. Local to global drivers of plant disease change in response to disasters, often creating environments more conducive to plant disease. Most disasters have indirect effects on plant health through factors such as disrupted supply chains and damaged infrastructure. There is also the potential for direct effects from disasters, such as pathogen or vector dispersal due to floods, hurricanes, and human migration driven by war. Pulse stressors such as hurricanes and war require rapid responses, while press stressors such as climate change …

Year-Round Co2 Emissions From The Drawdown Area Of A Tropical Reservoir: Strong Seasonal And Spatial Variation, Ícaro Barbosa, José R. Paranaíba, Sebastian Sobek, Sarian Kosten, Rafael M. Almeida, Vitor Duque, Natália Mendonça, Nathan Barros, Raquel Mendonça

School of Earth, Environmental, & Marine Sciences Faculty Publications

Highlights

• Drawdown areas emitted 80% of reservoir CO2 with just 1/5 area.

• Emissions from reservoir shorelines near forests were greater than from areas near grassland.

• CO2 emissions increase with the distance from the water.

• Estimates of reservoir drawdown CO2 flux vary by ∼ 300 % across the seasons examined here.

• There was no discernible difference in CO2 emissions between day and night-time.

• A significant increase in CO2 fluxes was observed 30 min after a rewetting event.

Abstract

A growing body of literature points to drawdown areas as important sources of atmospheric CO2 within reservoirs. Yet seasonal and temporal patterns of …

Cyanoacrylate Deposition Onto Sebum With Pretreatment Of Amine, Isaac Baltz

Chemistry & Biochemistry Undergraduate Honors Theses

Super glue, or ethyl cyanoacrylate, fuming is commonly used in forensic science to develop latent fingerprints on nonporous surfaces[7]. Fingerprints are primarily made up of the oily substance secreted by sebaceous glands better known as sebum. Previously it has been shown that exposure of fingerprints to diisopropylamine dramatically increases the deposition of cyanoacrylate polymers on the fingerprints[1]. However, the heterogeneity of any series of real fingerprints made it difficult to quantitatively assess this effect. This heterogeneity includes not just the amount of sebum but the presence of unknown amounts of proteins, amino acids, and other potential nucleophiles which catalyze the …

Utilizing Electrical Geophysical Methods To Map Mycorrhizal Mycelium Networks Non-Invasively, Donald Pesonen

Graduate Dissertations and Theses

Mycorrhizal mycelium networks are a key component to forest health. These networks act as a transportation system for nutrients, are major players in carbon and nitrogen cycling, and can provide some level of drought resistance to the surrounding flora. Due to the location and size of these network’s filaments, studying mycelium non-invasively has been difficult. The alternative method of laboratory grown samples, lacks the important environmental factors that play into the growth and development of mycelium. Mycelium’s inherent conductivity and moisture retention allows for these networks to be a viable target for electrical geophysical equipment. CMD-Tiny, a small shallow depth …

Project Foresight Annual Report, 2022-2023, Paul Speaker

Faculty & Staff Scholarship

Project FORESIGHT is a business-guided self-evaluation of forensic science laboratories across the globe. The participating laboratories represent local, regional, state, and national agencies. Economics, accounting, finance, and forensic faculty provide assistance, guidance, and analysis. Laboratories participating in Project FORESIGHT have developed standardized definitions for metrics to evaluate work processes, linking financial information to work tasks, and functions. Laboratory managers can then assess resource allocations, efficiencies, and value of services—the mission of Project FORESIGHT is to measure, preserve what works, and change what does not.

The benchmark data for the 2022-2023 performance period includes laboratory submissions for a variety of fiscal …

Modeling Sex-Specific Changes In Myocardial Fibrosis, Grace Martin

Chemical Engineering Undergraduate Honors Theses

Heart disease the leading cause of death for both men and women in the United States. Cardiac fibrosis, or accumulation of extracellular matrix proteins in the heart, can occur after a heart attack and increase the risk for further complications. Current treatments for heart disease do not include extracellular matrix regulators, partly due to the complicated signaling network responsible for the production of these proteins. By using a computational model of the signaling network in cardia fibroblasts, the relationship between particular molecules and downstream extracellular matrix production can be examined.

Biological sex is an important factor for cardiac health and …

Investigation Of K-2 Teachers' Self-Efficacy In One Rural School District, Crystal Schaefer

Curriculum and Instruction Undergraduate Honors Theses

In the past four years education has undergone many changes, whether it be shifting to distance learning in 2020 or changing student behaviors, and these changes have undeniable effects on teachers and their self-efficacy. The purpose of this study is to investigate teachers’ sense of self-efficacy. A 24-question Qualtrics survey was distributed through email for kindergarten through second grade teachers between two elementary schools in one rural Arkansas school district. These 24 questions were adapted from The Teachers’ Sense of Efficacy Scale. The survey collected 16 total responses. The survey results provided evidence that teacher efficacy in instructional strategies is …

An Examination Of Products That University Of Mississippi Students Consume For Managing Their Stress, Kiersten Rickard

Honors Theses

Students are notoriously one of the most stressed groups in our society. Stress is a complex topic; causes, mitigation methods, and manifestations of stress all vary in an individual. Being that stress is an universal experience, this research capitalizes on the importance of stress and the methods used to mitigate stress. This study looks at, among other ideas, stress on the University of Mississippi campus in regards to demographics and the products (caffeine, sleep aids, over the counter medicines, stress supplements, and CBD) that students use. Results demonstrate that, overall, higher stress levels correlate to higher product usage rates. The …

Fungi In Cancer, Jessica Galloway-Peña, Iliyan D Iliev, Florencia Mcallister

Faculty, Staff and Student Publications

Both the gut and the tumour microbiome are now established as crucial regulators of cancer phenotypes and have been implicated in cancer initiation, progression and therapy response. Although the role of bacteria in these processes is beginning to be unravelled, the relevance of fungi is only just emerging. In this Viewpoint, we asked experts to discuss the current knowledge on the mycobiome–cancer connection and share their opinion on how to best solve open questions.

Impact Of Revised International Staging System 2 Risk Stratification On Outcomes Of Patients With Multiple Myeloma Receiving Autologous Haematopoietic Stem Cell Transplantation, Kamal Alzahrani, Oren Pasvolsky, Zhongya Wang, Denái R Milton, Mark R Tanner, Qaiser Bashir, Samer Srour, Neeraj Saini, Paul Lin, Jeremy Ramdial, Yago Nieto, Hans C Lee, Krina K Patel, Elisabet E Manasanch, Partow Kebriaei, Sheeba K Thomas, Donna M Weber, Robert Z Orlowski, Elizabeth J Shpall, Richard Champlin, Muzaffar H Qazilbash

Faculty, Staff and Student Publications

The second revision of the International Staging System (R2-ISS) is a simple tool to risk-stratify newly diagnosed multiple myeloma (NDMM) patients. Here, we completed a retrospective analysis to evaluate the utility of R2-ISS in NDMM patients who underwent up-front autologous haematopoietic stem cell transplantation (auto-HCT). A total of 1291 patients were included, with a median age of 62 years (range 29-83). The distribution of R2-ISS stages was: 123 (10%) stage I, 471 (36%) stage II, 566 (44%) stage III and 131 (10%) stage IV. With a median follow-up of 42.2 months (range 0.3-181.0), the median PFS was 73.0, 65.2, 44.0 …

Impact Of Pretransplant Minimal Residual Disease In Patients With Multiple Myeloma And A Very Good Partial Response Or Better Receiving Autologous Hematopoietic Stem Cell Transplantation, Oren Pasvolsky, Sarah Pasyar, Roland L Bassett, Hina N Khan, Mark R Tanner, Qaiser Bashir, Samer Srour, Neeraj Saini, Paul Lin, Jeremy Ramdial, Yago Nieto, Hans C Lee, Krina K Patel, Partow Kebriaei, Sheeba K Thomas, Donna M Weber, Robert Z Orlowski, Elizabeth J Shpall, Richard E Champlin, Muzaffar H Qazilbash

Faculty, Staff and Student Publications

Background: The prognostic significance of minimal residual disease (MRD) status before autologous hematopoietic stem cell transplantation (autoHCT) in patients with multiple myeloma (MM) has not been clearly elucidated.

Methods: Retrospective single-center study of adult MM patients who achieved ≥very good partial response (VGPR) after induction therapy from 2015 to 2021 received upfront autoHCT and had available pretransplant MRD status by next-generation flow cytometry. The cohort was divided into pretransplant MRD-negative (MRDneg) and MRD-positive (MRDpos) groups.

Results: A total of 733 patients were included in our analysis; 425 were MRDneg and 308 MRDpos at autoHCT. In the MRDpos group, more patients …

Onc201 (Dordaviprone) In Recurrent H3 K27m-Mutant Diffuse Midline Glioma, Yazmin Odia, Minesh Mehta

All Publications

Purpose: Histone 3 (H3) K27M-mutant diffuse midline glioma (DMG) has a dismal prognosis with no established effective therapy beyond radiation. This integrated analysis evaluated single-agent ONC201 (dordaviprone), a first-in-class imipridone, in recurrent H3 K27M-mutant DMG.

Methods: Fifty patients (pediatric, n = 4; adult, n = 46) with recurrent H3 K27M-mutant DMG who received oral ONC201 monotherapy in four clinical trials or one expanded access protocol were included. Eligible patients had measurable disease by Response Assessment in Neuro-Oncology (RANO) high-grade glioma (HGG) criteria and performance score (PS) ≥60 and were ≥90 days from radiation; pontine and spinal tumors were ineligible. The …

Hierarchal Single-Cell Lineage Tracing Reveals Differential Fate Commitment Of Cd8 T-Cell Clones In Response To Acute Infection., Leena Abdullah

Dartmouth College Ph.D Dissertations

Generating balanced populations of CD8 effector and memory T cells is necessary for immediate and durable immunity to infections and cancer. Yet, a definitive understanding of CD8 differentiation remains unclear. Here we used CARLIN, a processive lineage recording mouse model with single-cell RNA-seq and TCR-seq to track endogenous antigen-specific CD8 T cells during acute viral infection.

Transcriptional profiling of antigen-specific T cells at the peak of the effector response to Vesicular stomatitis virus uncovered a diverse repertoire of expanded antigen-specific T-cell clones represented by seven transcriptional states. TCR enrichment analysis identified TCR clones with differential memory- or effector-fate biases during …

Thinking From The Home: Emanuele Coccia On Domesticity And Happiness, Evan Edwards

Open Access Publishing Support Funded Articles

This article traces the idea of domesticity through the work of Emanuele Coccia to explain his conception of happiness. Coccia argues that it is only by taking domestic concerns seriously that philosophy can begin to theorize the possibility of happiness today, claiming that rather than beginning with the polis, “philosophy must think the city from the home, and the home from the kitchen.” The article begins by situating Coccia's work in the tradition of Giorgio Agamben's critical project and then explores the idea of the home from his 2016’s The Life of Plants through 2020’s Metamorphoses to understand the reason …

Catchment-Scale Thawing And Greening Decreases Long-Term Nitrogen Export In Ne Greenland, Shannon L. Speir, Jennifer L. Tank, Ada Pastor, Marc F. Muller, Mikhail Mastepanov, Tenna Riis

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Climate change is expected to alter nitrogen (N) export from Arctic rivers, with potential implications for fragile coastal ecosystems and fisheries. Yet, the directionality of change is poorly understood, as increased mobilization of N in a 'thawing' Arctic is countered by higher rates of vegetative uptake in a 'greening' Arctic, particularly in the understudied region of Greenland. We use an unprecedented dataset of long-term (n = 18 years) river chemistry, streamflow, and catchment-scale changes in snow and vegetation to document changing riverine N loss in Greenland. We documented decreasing inorganic and organic N loads, linked to decreasing snow stores, …

Impact Of Perinatal Escitalopram Exposure On Adolescent Behavior, Jessica Bezenah - Bottorff

Electronic Theses, Projects, and Dissertations

Escitalopram (EST), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant frequently used during pregnancy, yet there is limited knowledge of its long-term effects on maternal use. Past studies suggest that maternal exposure may adversely affect the fetus, which may be due to the hyperserotonergic environment caused by the nature of SSRIs during early development. Modifications of the serotonergic system in offspring during certain critical periods of development may result in long-term behavioral and cognitive changes in adulthood. Further, recent human studies have demonstrated that prenatal exposure to SSRIs in humans may increase susceptibility to autism spectrum disorder (ASD) and …

Major Factors Of Sustaining Recovery After Relapse From A Substance Use Disorder, Amanda Tei Sandhurst

Electronic Theses, Projects, and Dissertations

Relapse is a common and often-expected occurrence among individuals with substance use disorders. Relapse can be defined as returning to a problematic behavior after abstaining for a period of time (Marlatt & Witkiewitz, 2005). It is the inability to maintain life in sobriety and is not an isolated event, but rather a process (Gorski & Kelley, 1996). The problem with relapse is that it can result in continued substance use and abuse, which can then lead to other major consequences. This study looks at ten individuals in recovery who experienced a past relapse after having a period of abstinence and …

Career Motivation As Mediator Between Cultural Self-Construal And Interest, Mengxuan Zhang

Electronic Theses, Projects, and Dissertations

Understanding the association between career motivations and interest-occupation congruence can help people with different cultural backgrounds make better career decisions. The goal of the study was to examine how cultural differences predicted interest congruence, and whether career motivation was a significant mediator in the prediction. I hypothesized that independent self-construal would be associated with internal career motivation most strongly (H1), while interdependent self-construal will be associated with interpersonal career motivation most strongly (H2). Additionally, internal career motivation would mediate the relationship between independent self-construal and interest congruence (H3), and whether internal career motivation mediated the relationship between interdependent self-construal and …

Child Maltreatment Primary Prevention Methods In The U.S.: A Systematic Review Of Recent Studies, Maria Godoy-Murillo

Electronic Theses, Projects, and Dissertations

Background: Child maltreatment remains a widespread issue in the United States of America, (U.S.). Identifying effective methods of preventing child maltreatment is key to reducing the prevalence of this issue. Objective: This systematic review provides an overview of contemporary primary child maltreatment prevention methods in the U.S. to investigate their effectiveness. Methods: Using the OneSearch database, the following keywords were included: (“prevention methods” and “child maltreatment”), (“parental leave” and “child maltreatment”), (“primary prevention” and “child maltreatment”), (WIC and “child maltreatment”), (“home visit” and “child maltreatment”), (“child abuse and neglect” and “primary prevention”), (“affordable housing” and prevention and “child maltreatment”), (“early …

Educational Outcomes For Youth That Participated In Extended Foster Care: A Systematic Review, Kassandra Mayorga, Roxana Sanchez

Electronic Theses, Projects, and Dissertations

Background: Transitioning to adulthood poses significant obstacles for foster youth adults, who encounter disproportionately elevated rates of homelessness, school underperformance, unemployment, and mental health concerns in comparison to their peers. Extended Foster Care (EFC) programs seek to tackle these difficulties by offering assistance in housing, employment, and education. However, there have been few systematic efforts to review the effectiveness of the EFC program. Objective: The purpose of this systematic review was to identify, evaluate, and synthesize the empirical evidence on the educational outcomes of foster youth who have participated in EFC. Methods: This review was conducted during …

Investigating The Level Of Evidence Of Adverse Childhood Experiences And Parenting Practices: A Systematic Review, Eloisa Deshazer

Electronic Theses, Projects, and Dissertations

Background: Adverse childhood experiences (ACEs) are associated with mental and physical health outcomes of children, but less is known about how ACEs impact parenting. Objective: This study systematically reviewed the evidence of the association between parental adverse childhood experiences and parenting behaviors. Methods: The study employed a rigorous methodology, including searching several electronic databases, such as the CSUSB search engine, EBSCOhost Academic Search Premiere, PsycINFO, PubMed, and ScienceDirect. The keywords used for the search process included Adverse Childhood Experiences, ACEs, Maltreatment, Adverse Experiences, Traumatic Experiences, and Parenting or Childrearing. Inclusion criteria were restricted to studies published between 2014 and …

Is A Social Support Based Model Better For Treating Alcoholism? A Systematic Review, Jordan Anthony Contreras

Electronic Theses, Projects, and Dissertations

Alcoholism continues to persist as a significant health issue in the United States and impacts individuals and families across race, gender, and age. While much work has been made in the field of substance abuse treatment, there remains a substantial need for additional research to formulate effective strategies for treating alcoholism and related unhealthy drinking behaviors. The existing literature suggests that mutual support groups such as Alcoholics Anonymous are the standard for achieving successful recovery among those seeking help. Simultaneously, there exists a growing amount of research proposing a range of other interventions that may prove effective in treating alcoholism. …

Factors That Impact Foster Youths’ High School Graduation, Esther Thomas

Electronic Theses, Projects, and Dissertations

This study examines the factors that influence foster youth high school graduation rates. Over 50% of foster youth do not graduate high school and even fewer enroll in higher education. The study analyzes social workers’ belief about foster youth high school graduation. Social workers have direct contact with and influence on foster youth, so understanding the extent to which there, beliefs and actions factor into foster youth graduation rates seems important.

This study utilized a quantitative, online survey designed by the researcher to collect exploratory data. The researcher posted invitations to participate in the study on social media sites used …

Resilience In Fatherhood: Exploring The Impact Of Absent Fathers On Black American Men's Parenting Narratives And Practices, Ericah Thomas

Electronic Theses, Projects, and Dissertations

This study explores the role of Black American fathers and how they parent in the absence of their fathers growing up. Though a common narrative frames Black fathers as largely absent in the lives of their children, recent literature has aimed to demystify societal factors that may lead to this judgment. Influences such as media representation, welfare policies, and child support laws may contribute to the preservation of this trope (Rambert, 2021). Considering this misconception, it is important to advance the knowledge regarding Black fatherhood through their lived experiences despite circumstances that may perpetuate this myth.

The primary goal of …