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Navigating The Future: Advancing Fisheries Predictions With A Front-To-Fish Approach, D. M. Lal, Harisha, N. Nagaswetha, A. Samanta

Open Access archive

Oceans, vast reservoirs of abundant fish and marine life, exhibit varying exploitation and utilisation potential across space and time. A comprehensive understanding of the complex interaction between the environment, biology, and fish movements is crucial for accurately predicting fishing grounds, a key prerequisite for sustainable fisheries. The application of remote sensing technology has significantly enhanced the predictive capabilities on fisheries. It can portray environmental variables linked to productivity across the ocean, effectively identifying potential fishing grounds. Fishing grounds around the world are often found along current boundaries, upwelling zones, eddies, continental shelves, and reef banks. Oceanic fronts typically mark these …

A Cytoarchitectural Analysis Of The Rat Amygdala In Ultrathin Serial Sections, Katrina Schneider

Honors Scholar Theses

This study delves into the cellular composition and functional dynamics of the lateral amygdala (LA), a crucial brain region implicated in emotional and auditory processing/learning. Utilizing IHC, ultrathin serial sectioning (Ultraplex Method), and RNAscope, distinct cell types are characterized within the LA based on calcium-binding proteins (CBPs) and inhibitory markers such as GABA. Despite a modest sample size, a diverse array of cell types are identified, with calbindin-positive neurons prominently emerging in inhibitory cells. Notably, GABA intensity varies depending on cell identity and marker colocalization, hinting at complex regulatory mechanisms involving GABAergic signaling and CBPs. Analysis of vesicular glutamate transporter …

Cpeb3 Maintains Developmental Competence Of The Oocyte, Lucie Lamacova, Denisa Jansova, Zongliang Jiang, Michal Dvoran, Daria Aleshkina, Rajan Iyyappan, Anna Jindrova, Heng Yu Fan, Yuxuan Jiao, Andrej Susor

Faculty Publications

Mammalian oocyte development depends on the temporally controlled translation of maternal transcripts, particularly in the coordination of meiotic and early embryonic development when transcription has ceased. The translation of mRNA is regulated by various RNA-binding proteins. We show that the absence of cytoplasmic polyadenylation element-binding protein 3 (CPEB3) negatively affects female reproductive fitness. CPEB3-depleted oocytes undergo meiosis normally but experience early embryonic arrest due to a disrupted transcriptome, leading to aberrant protein expression and the subsequent failure of embryonic transcription initiation. We found that CPEB3 stabilizes a subset of mRNAs with a significantly longer 3’UTR that is enriched in its …

Effects Of Age And Gender On Perceptions On Victims Of Financial Exploitation, Kathleen Hillman

Honors Theses

A report by the Center for Victim Research shows that younger adults are more often victims of general and identity fraud (Irvin-Erickson & Ricks, 2019, p. 9); however, research conducted on financial exploitation focuses heavily on older adults. However, a recent study by Gunderson and colleagues (2021) found that older and younger adults are highly susceptible to financial exploitation. The purpose of the current study is to determine if perceptions of vulnerability to financial exploitation vary by the age of the victim. A sample of undergraduate participants will be recruited from the University of Tennessee at Chattanooga through an online …

Screening Full-Sib And Half-Sib Families Of Chestnut Seedlings For Resistance To Cryphonectria Parasitica Using A Small Stem Assay And A Leaf-Disc Assay, Uma Plambeck

Honors Theses

Cryphonectria parasitica is the ascomycete fungus species that causes chestnut blight disease. Symptoms of chestnut blight include bark cankers and eventually the death of American chestnut, Castanea dentata. However, not all Castanea species are equally affected by the disease, and some Asian species appear highly resistant. The OALDS and SSA in this study aim to assist in screening for resistance to C. parasitica within a year. We investigated the effect of C. parasitica on three North American species, one European species, four East Asian species of Castanea, and nine full-sib families of TACF backcross hybrids. Our study used both a …

Effects Of Attractiveness And Relationship Type Of Perceptions Of Adolescent Sexual Grooming, Alexandra Shappley

Honors Theses

Child sexual grooming is a prevalent issue within the United States, especially with the rise of the internet and social media (Shakeshaft, 2004; Finkelhor et al., 2000; Winters et al., 2017). There has been less research done on adolescent sexual grooming; however, researchers have found that perceptions of adolescent sexual grooming vary depending on the gender and age of the offender and victim (Russel & Gyrus, 2022; Sahl & Keene, 2012). Researchers have found that people perceive a sexual grooming relationship as inflicting more harm if the perpetrator is a man (Hernandez et al., 2019), particularly an older man (Russel …

Microfaunal Remains From The Ryan-Harley Site, Savanna Caylor

Honors Theses

The Ryan Harley site is located in the Wacissa River basin in northern Florida. It is one of the few sites in the southeastern United States to contain a Suwannee point artifact. Several excavations in 2015 and 2017 showed extinct and extant faunal remains within and around the Suwannee component. The geoarchaeological data showed that whether these remains were in situ or not is inconclusive. This paper will focus on the microfloral and faunal remains to draw conclusions about the environment encountered during the Younger Dryas (12,900-11,700 cal B.P). The relationship between floral and faunal species present will help to …

Understanding The Perspectives And Attitudes Of 12-Step Participants Towards Medication-Assisted Treatment, Christopher Scott

Electronic Theses, Projects, and Dissertations

Background: The effects of living with a substance use disorder (SUD) are vast. Medication-assisted treatment (MAT) has grown increasingly popular as a recovery tool among substance users but does not align with the popular 12-step model, which demands complete abstinence from narcotics and mind-altering substances. Objective: The primary aim of this phenomenology study was to explore the perspectives and attitudes towards MAT among 12-step participants. The secondary aim was to compare the responses of treatment and non-treatment professionals. Methods: This study used non-probability sampling methods to recruit participants who reported regular participation in a 12-step program. Semi-structured …

Recommendation System Using Machine Learning For Fertilizer Prediction, Durga Rajesh Bommireddy

Electronic Theses, Projects, and Dissertations

This project presents the development of a sophisticated machine-learning model aimed at enhancing agricultural productivity by predicting the optimal fertilizer suited to specific crop requirements. Leveraging a diverse set of features including soil color, pH levels, rainfall, temperature, and crop type, our model offers tailored recommendations to farmers. Three powerful algorithms, Support Vector Machines (SVM), Artificial Neural Networks (ANN), and XG-Boost, were implemented to facilitate the prediction process. Through comprehensive experimentation and evaluation, we assessed the performance of each algorithm in accurately predicting the best fertilizer for maximizing crop yield. The project not only contributes to the advancement of machine …

The Study Of Dmrt1 In Zebrafish And How It Impacts Sex Determination, Raymond Michael Poirier

Graduate Masters Theses

The dmrt1 gene is common amongst most animals and functions to determine or maintain male sex during development. Similarly, in zebrafish dmrt1 is important for male sex determination and maintaining proper testis morphology. This gene is expressed in two different cell types of the testis in zebrafish, germ cells and Sertoli cells. While we know where this gene is expressed and what its role is, it is not known if it is sufficient to drive male fate. If so, then in which cells is it sufficient to drive male fate in the testis? I aimed to answer this question by …

Imagined Intergroup Contact As A Mechanism To Change Beliefs About Gender, Samantha Oyler

Honors Theses

Gordon Allport first proposed the Intergroup Contact Theory in 1954. According to his theory, contact between ingroup and outgroup members, under certain conditions, would lead to positive effects, specifically the reduction of prejudice. Since then, this theory has been expanded to include members of other majority/minority groups. Research suggests intergroup contact has positive effects for reduction of anti-trans prejudice. To date, the focus has largely been on the mechanisms driving changes in attitudes and intentions towards trans individuals through intergroup contact interventions. It is unclear whether this intervention might also promote the acquisition of more nuanced sociocultural understanding about gender, …

Investigating Thin Filament Assembly In C. Elegans Muscles, Angela Russ

Honors Theses

All striated muscles are composed of small units called sarcomeres [1]. Within each sarcomere, there are thin filaments composed of actin and thick filaments composed of myosin. The thin filaments extend from either end of the thick filament towards the middle of the sarcomere. The lengths of thin filaments are correlated to muscle contraction and force production [1], but it is currently unknown what regulates their lengths. Prior hypotheses based on vertebrate models have focused on a nebulin ruler model [2]. However, nebulin is not present within invertebrate muscles, and this has led to a major gap in the field’s …

Civil Disobedience Of Social Workers In Hospice, Jamie Leigh Roper

Honors Theses

No abstract provided.

An Attentionless Account Of The Attentional Blink, Matthew Stephen Junker

Dissertations

Theories of the attentional blink (AB) – a deficit in responding to the second of two temporally proximal stimuli (within 500 ms; Raymond et al., 1992) – generally explain the deficit as resulting from either the dynamics in top-down and bottom-up attentional process, or limitations in the capacity of the hypothesized attentional process. Extensive basic research has been conducted on the neural correlates of top-down and bottom-up attention as well as on the capacity limitations of attention; however, rather than leading to a single definition, the variety and complexity of results has led several taxonomies which differ systematically with the …

“No One Likes A Mad Woman:” A Modern Reclamation Of Solitude In The Domestic Space Through Women With Invisible Disabilities In A Post-Lockdown World, Marley Ashton Bickley

All Theses

This project weaves together critical and creative writing to highlight personal narratives from women with mental illnesses and invisible disabilities. Through a historical recognition of the "madwoman" who is framed as hysterical to be a scapegoat for patriarchal control, I examine societal attempts to immobilize women’s rights to free will and agency from the nineteenth century until today. My analysis of "madwomen" in domestic space takes up fiction writing such as Charlotte Perkins Gilman’s The Yellow Wallpaper and Charlotte Brontë's Jane Eyre where women are forced into confinement against their will. In a flipped-script narrative, I reexamine how domestic space …

Transcriptomic Profile Of Armillaria Root Rot Fungi Affecting The U.S. Stone Fruit Industry, Jared Weaver

All Theses

Armillaria Root Rot (ARR) is a significant replant disease threatening the future of the United States stone fruit industry. Economic loss in South Carolina peach orchards is estimated to be $8M annually due to approximately 3-4% of annual tree deaths caused by ARR on replant sites. Management solutions are insufficient and can at best extend the life of the orchards on replant sites. The only solution to solving the ARR problem, apart from abandoning the replant site for peach production, is planting orchards on ARR-resistant rootstock. Significant progress has been made towards providing growers with genetically resistant rootstock, however, for …

Characterization Of Ato Family Transporters In The Fungal Pathogen Cryptococcus Neoformans, Will Betsill

All Theses

Fungal pathogens are a significant threat to public health as they are becoming increasingly common and more resistant to treatment. Cryptococcus neoformans contributes greatly to this threat annually by causing an estimated 278,000 cases of cryptococcal meningitis resulting in approximately 181,000 deaths globally according to the CDC. C. neoformans is ubiquitous across most of the globe and can be found in such places as in trees or soil. Exposure to this fungus is especially dangerous to individuals who are immunocompromised or immunosuppressed. In these cases, inhalation of spores can lead to infection in the lungs. Once in the lungs, C. …

Additive Manufacturing Of Porous Tungsten Carbide Structural Electrode Components Using Robocasting, James Bevis

All Theses

Thanks to ideal mechanical and electrochemical properties, Tungsten Carbide (WC) shows excellent potential as a structural electrode material for multifunctional devices. These devices have applications in electric vehicles, for example, structural fuel cells and massless batteries. In such a context, structural WC electrodes will also benefit from porosity to decrease their weight and increase their surface area and chemical reactivity. Porous WC is a useful material for this field because of its high strength-to-weight ratio and electrical properties. However, current manufacturing methods can be expensive, complex, and limited, so the intent is to provide a more simplistic and sustainable method …

Efficacy Of Virtual Reality-Based Simulations In Training Aviation Maintenance Technicians On Maintenance Procedures, Gayatri Anoop

All Theses

The COVID-19 pandemic forced institutions of higher education (IHEs) to halt in-person classes and transition to online platforms. Given the intricate process of adapting hands-on experiments to the online environment, this transition seemed particularly challenging for Science, Technology, Engineering, Mathematics, and Medicine (STEMM) labs. The abrupt nature of this transition added to the difficulties, given that the IHEs were inadequately prepared for seamless continuity during the pandemic. In the first phase of this project, a literature review was conducted to understand the impact of COVID-19 pandemic on education. Specifically, the review explored the challenges that institutions of higher education faced, …

Investigation Of Domain Formation During Phase Separation In A Mixture Of Flexible And Rigid Biopolymers, Steven Huntley

All Theses

Complex fluids and heterogenous mixtures composed of multiple types of polymers are found throughout industrial and biological fluid systems. For example, extrusion based additive manufacturing systems pass dense mixtures of polymers through the extrusion heads to deposit composite polymeric materials. In cells, active and complex mixtures of biopolymers self-organize into assemblies that perform critical physiological functions.

Polymers in dense solutions undergo phase separation as a result of differences in physiochemical properties. A few examples of these properties include charge, structure, rigidity, and hydrophobicity. We observe the formation of polymer domains composed of rigid and a flexible biopolymer species that phase …

Tri-Colored Bat Habitat Use And Selection In Northwestern South Carolina, Eduardo Rosales

All Theses

North American bat populations continue to be decimated by many factors, with the largest contributor being white-nose syndrome (WNS). In recent years researchers have noted the importance of fat reserves pre- and post-hibernation (fall and spring) and how they may influence WNS survival and recovery respectively. Tri-colored bats (Perimyotis subflavus) are one of the four species most impacted by WNS but have received the least research. Further, thus far all research on tri-colored bat resource selection has been gathered during summer and winter, highlighting the need for habitat selection studies during the fall and spring pre- and post-hibernation …

Advancements Of A Breast Tissue Marker And Localization System, Azrin Jamison

All Theses

Breast cancer has become the most prominent cancer worldwide in women. Annual mammograms are encouraged for women of high risk to increase early detection allowing for lumpectomies rather than mastectomies to occur. Prior to a lumpectomy, a biopsy must be taken to determine if the tissue is cancerous, and a breast cancer biopsy marker (BBM) is left in the region of possible cancerous tissue. Wire localization has been the gold standard for localizing these BBMs. However, due to the reported patient discomfort and logistical inefficiencies faced by healthcare providers (HCP), non-wire localization solutions have been recently developed. This study aims …

Yield And Nutritive Quality Of Fresh And Ensiled Reduced Lignin Alfalfa In Monoculture And Diculture With Novel Tall Fescue, Morgan Boss

All Theses

The objectives of this research were to: (1) evaluate the yield, nutritional value, and digestibility of fresh and ensiled reduced lignin alfalfa (RLA; Medicago sativa L.) in monoculture and when mixed with novel endophyte-infected tall fescue (F; Festuca arundinacea) in comparison to a conventional alfalfa (CA) cultivar; and (2) evaluate ensiled samples under varying DM concentrations; with or without inoculant. A trial was prepared as a randomized complete block design with 4 replicates per treatment. Treatments included reduced lignin alfalfa (RLA), conventional alfalfa (CA) and tall fescue (F) plots as well as RLA/F and CA/F plots. Plots were harvested on …

Online Political Participation Among Younger Generations: A Case Study Of The Nigerian Presidential Election, Bowale Odukale

All Theses

The 2023 presidential elections in Nigeria represented a significant milestone in the nation's democratic progression, capturing the interest of observers both within the country and abroad. This study identifies the key online opinion leaders who participated in the electoral discourse, their generational affiliation, and the role of social media in facilitating youth engagement throughout the political process. Using Sprinkl, an online monitoring tool to harvest publicly available tweets containing the hashtag #NigeriaDecides2023 from February 11 to March 15, coupled with interviews, the study identified the prominent opinion leaders with significant influence, their types of messages and the motives behind youth …

A Building Worth Its Salt: Residual Chloride Exposure From Frequent Inundation In 19th-Century Masonry Construction On The Battery Of Charleston, South Carolina, Sarah Gaston

All Theses

The growing frequency of intense storm events, minor coastal flooding, and salinity levels of the rising groundwater tables in Special Flood Hazard Areas, including those within Charleston, South Carolina, are affecting historic buildings and their masonry materials in a manner that is only beginning to be discussed in the field of Architectural Conservation. By determining the quantity and location of salt deposits within the mortar measured vertically along historic brick walls, this thesis contributes to the understanding of flooding impacts on historic buildings. This thesis analyzes the distribution of chloride vertically up brick or stucco-clad walls of 19th-century masonry buildings …

Improved Ballistic Impact Resistance Of Nanofibrillar Cellulose Films With Discontinuous Fibrous Bouligand Architecture, Colby Caviness

All Theses

Natural protective materials offer unparalleled solutions for impact-resistant material designs that are simultaneously lightweight, strong, and tough. Particularly, the dactyl club of mantis shrimp features chitin nanofibrils organized in a Bouligand structure, which has been shown to effectively dissipate high-impact energy during powerful strikes. The mollusk shells also achieve excellent mechanical strength, toughness, and impact resistance with a staggered, layer-by-layer structure. Previous studies have shown that hybrid designs, by combining different bioinspired microstructures, can lead to enhanced mechanical strength and energy dissipation capabilities. Nevertheless, it remains unknown whether combining Bouligand and staggered structures in nanofibrillar cellulose (NFC) films, forming a …

Low Absolute Risk Of Thrombotic And Cardiovascular Events In Outpatient Pregnant Women With Covid-19, Behnood Bikdeli, Darsiya Krishnathasan, Candrika Khairani, Antoine Bejjani, Julia Davies, Nicole Porio, Anthony Tristani, Andre Armero, Ali Assi, Victor Nauffal, Umberto Campia, Zaid Almarzooq, Eric Wei, Marcos Ortiz-Rios, Valeria Zuluaga-Sánchez, Aditya Achanta, Sirus Jesudasen, Bruce Tiu, Geno Merli, Orly Leiva, John Fanikos, Elvira Grandone, Aditya Sharma, Samantha Rizzo, Mariana Pfeferman, Ruth Morrison, Alec Vishnevsky, Judith Hsia, Mark Nehler, James Welker, Marc Bonaca, Brett Carroll, Samuel Goldhaber, Zhou Lan, Gregory Piazza

Division of Cardiology Faculty Papers

INTRODUCTION: Pregnancy may contribute to an excess risk of thrombotic or cardiovascular events. COVID-19 increases the risk of these events, although the risk is relatively limited among outpatients. We sought to determine whether outpatient pregnant women with COVID-19 are at a high risk for cardiovascular or thrombotic events.

MATERIALS & METHODS: We analyzed pregnant outpatients with COVID-19 from the multicenter CORONA-VTE-Network registry. The main study outcomes were a composite of adjudicated venous or arterial thrombotic events, and a composite of adjudicated cardiovascular events. Events were assessed 90 days after the COVID-19 diagnosis and reported for non-pregnant women ≤45 years, and …

Impact Of Socioeconomic Inequalities On Racial/Ethnic Disparities In Adrd Incidence Rate In South Carolina, Noor Nishan

All Theses

none

Environment And Response Of 3d-Encapsulated Mesenchymal Stem Cells To Mechanical Loading, Augustus Greenwood

McKelvey School of Engineering Graduate Student Theses & Dissertations

This thesis explores the micromechanical environment induced when cyclically compressing hydrogels via finite element modeling and experimentally on the impact of loading on mesenchymal stem cells (MSCs) when encapsulated withing 3D hydrogel matrices. Degenerative joint diseases, characterized by cartilage degradation, present significant challenges due to cartilage's limited self-repair capacity. Innovative approaches, including stem cell-based therapies and engineered biomaterials, have emerged as promising strategies for cartilage repair and regeneration. This work specifically investigates the calibration of a bioreactor, the uniformity of load response across the hydrogel constructs via finite element modeling (FEM), and the stress response of MSCs subjected to various …

Physiological And Morphological Plasticity In Response To Nitrogen Availability Of A Yeast Widely Distributed In The Open Ocean, Poppy Diver, Ben A. Ward, Michael Cunliffe

School of Biological and Marine Sciences

Yeasts are prevalent in the open ocean, yet we have limited understanding of their ecophysiological adaptations, including their response to nitrogen availability, which can have a major role in determining the ecological potential of other planktonic microbes. In this study, we characterized the nitrogen uptake capabilities and growth responses of marine-occurring yeasts. Yeast isolates from the North Atlantic Ocean were screened for growth on diverse nitrogen substrates, and across a concentration gradient of three environmentally relevant nitrogen substrates: nitrate, ammonium, and urea. Three strains grew with enriched nitrate while two did not, demonstrating that nitrate utilization is present but not …