Digital Commons Network^™

Facial Recognition Ai: Alaska Is An Ideal Forum For Introducing Regulation, Sarah Edwards

Alaska Law Review

As artificial intelligence becomes increasingly commonplace, we are all exposed to shockingly dystopian forms of surveillance. This Note details the unique danger of facial recognition technologies powered by artificial intelligence. First, this Note examines the rise of facial recognition technologies in both the public and the private sector. It illustrates this phenomenon by highlighting a few key players in both the development and implementation of facial recognition. Second, it proceeds by examining the current privacy landscape in Alaska. Alaska's unique focus on privacy rights makes the State a promising forum for regulation. Finally, it provides possible statutory and judicial solutions …

Travel-Time Disparities In Access To Proton Beam Therapy For Cancer Treatment, Todd Burus, Alexander D. Vanhelene, Michael K. Rooney, Krystle A. Lang Kuhs, W. Jay Christian, Christopher Mcnair, Sanjay Mishra, Arnold C. Paulino, Grace L. Smith, Steven J. Frank, Jeremy L. Warner

Markey Cancer Center Faculty Publications

IMPORTANCE Proton beam therapy is an emerging radiotherapy treatment for patients with cancer that may produce similar outcomes as traditional photon-based therapy for many cancers while delivering lower amounts of toxic radiation to surrounding tissue. Geographic proximity to a proton facility is a critical component of ensuring equitable access both for indicated diagnoses and ongoing clinical trials.

OBJECTIVE To characterize the distribution of proton facilities in the US, quantify drive-time access for the population, and investigate the likelihood of long commutes for certain population subgroups.

DESIGN, SETTING, AND PARTICIPANTS This population-based cross-sectional study analyzed travel times to proton facilities in …

Adaptive Parameter Tuning For Robust Event-Based Slam In Diverse Scenarios, Saber Muawiyah Sakhrieh

Theses

In the ever-changing field of contemporary robotics, Visual Simultaneous Localization and Mapping (V-SLAM) stands as a crucial technology, facilitating navigation and mapping in various environments. While traditional V-SLAM approaches excel in static environments, the need for their adaptation to handle dynamic and realistic scenes is becoming increasingly apparent. This thesis delves into the advancements within the V-SLAM field, with a focus on enhancing its adaptability and performance in dynamic and challenging conditions. Initially, a comprehensive review of V-SLAM methods in the literature is presented in this thesis, offering an in-depth examination of current cutting-edge techniques, their strengths, weaknesses, and prospects …

Pro-Resolving Lipid Mediator Reduces Amyloid-Β42-Induced Gene Expression In Human Monocyte-Derived Microglia, Ying Wang, Xiang Zhang, Henrik Biverstål, Nicolas G. Bazan, Shuai Tan, Nailin Li, Makiko Ohshima, Marianne Schultzberg, Xiaofei Li

School of Medicine Faculty Publications

JOURNAL/nrgr/04.03/01300535-202503000-00031/figure1/v/2024-06-17T092413Z/r/image-tiff Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte-derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42-induced Alzheimer's disease-like inflammation. Analysis of …

Design, Synthesis And Anticolorectal Cancer Activity Of 2- Bromoalkoxyanthraquinones, Yean Kee Lee, Wati Mekzali Nurhaliza, Wui Chee Cheok, Abdullah Iskandar, Nor Rashid Nurshamimi, Sanghiran Lee Vannajan, Othman Rozana, Mohd Hashim Najihah, Fei Chee Chin

Research Publications (2021 to 2025)

The impact of alkoxy chain length and the presence of a 1-hydroxy group in synthesised 2-bromoalkoxyanthraquinones was evaluated against HCT116, HT29, and CCD841 CoN cell lines. Molecular docking was employed to elucidate the interactions between these compounds and potential p53 and KRAS targets. Results indicated that 2-bromoalkoxyanthraquinones with the 1-hydroxy group exhibited greater anticancer activity compared to their counterparts. Specifically, compound 6b bearing C3 alkoxy chain displayed the most promising antiproliferation activity against HCT116 cells (IC50 = 3.83 ± 0.05 μM) and demonstrated high selectivity for HCT116 over CCD841 CoN cells (SI = 45.47). Molecular docking analysis revealed additional hydrogen …

The Role Of Aptes As A Primer For Polystyrene Coated Aa2024-T3, John H. Halford

Engineering

(3-Aminopropyl)triethoxysilane (APTES) silane possesses one terminal amine group and three ethoxy groups extending from each silicon atom, acting as a crucial interface between organic and inorganic materials. In this study, after APTES was deposited on the aluminum alloy AA2024-T3 as a primer for an optional top coating with polystyrene (PS), its role with regard to stability as a protection layer and interaction with the topcoat were studied via combinatorial experimentation. The aluminum alloy samples primed with APTES under various durations of concentrated vapor deposition (20, 40, or 60 min) with an optional post heat treatment and/or PS topcoat were comparatively …

Implications Of Detachment Promoting Agents, Disinfectants And Flow Hydraulics On Growth And Dispersion Of Bacterial Biofilms In Drinking Water Distribution Systems, Fayzul Kabir

Engineering

Biofilms in water distribution systems (WDS) can adversely affect the effluent water quality and structural integrity of pipes. Current disinfectants and flushing strategies often prove insufficient to mitigate biofilm growth. Long-term monitoring of biofilm growth under varied WDS flow and disinfection conditions is needed (and often overlooked) for improving biofilm management in the WDS. An alternative approach to counter biofilms in the WDS over the traditional approach of using antimicrobials is to target and weaken the extracellular polymeric substances (EPS) instead of just the microorganisms in the biofilms - via the use of 'detachment promoting agents' (DPAs) to weaken the …

Rabies Management In The North, A One Health Problem In A Systems Theory Framework, Karsten Hueffer

Arctic and Northern Studies

Rabies is a significant public health concern and is often described as the quintessential One Health problem, linking especially animal health to human health. I examine how rabies is managed in the circumpolar North with three cases: Alaska, Northwest Territories, and Svalbard. In this thesis, I describe rabies management in the North using a systems theory framework and explore challenges in this limited application of the One Health paradigm, focusing on animal and human health agencies and their interaction in rabies management in a northern environment. I conducted semi-structured interviews with fifteen key informants. My results indicate that most respondents …

Changes In Walking Function And Neural Control Following Pelvic Cancer Surgery With Reconstruction, Geng Li, Di Ao, Marleny M Vega, Payam Zandiyeh, Shuo-Hsiu Chang, Alexander N Penny, Valerae O Lewis, Benjamin J Fregly

Faculty, Staff and Student Publications

Introduction: Surgical planning and custom prosthesis design for pelvic cancer patients are challenging due to the unique clinical characteristics of each patient and the significant amount of pelvic bone and hip musculature often removed. Limb-sparing internal hemipelvectomy surgery with custom prosthesis reconstruction has become a viable option for this patient population. However, little is known about how post-surgery walking function and neural control change from pre-surgery conditions.

Methods: This case study combined comprehensive walking data (video motion capture, ground reaction, and electromyography) with personalized neuromusculoskeletal computer models to provide a thorough assessment of pre- to post-surgery changes in walking function …

Technical Pitfalls And Proposed Modifications Of Instructions For Use For Endovascular Aortic Aneurysm Repair Using The Gore Excluder Conformable Device In Angulated And Short Landing Zones, Zhengkai Yang, Jiaojiao Qu, Lu Qiao, Meiling Jiang, Xiao Zou, Wei Cao

Faculty, Staff and Student Publications

Intercropping with Pleurotus ostreatus has been demonstrated to increase the tea yield and alleviate soil acidification in tea gardens. However, the underlying mechanisms remain elusive. Here, high-throughput sequencing and Biolog Eco analysis were performed to identify changes in the community structure and abundance of soil microorganisms in the P. ostreatus intercropped tea garden at different seasons (April and September). The results showed that the soil microbial diversity of rhizosphere decreased in April, while rhizosphere and non-rhizosphere soil microbial diversity increased in September in the P. ostreatus intercropped tea garden. The diversity of tea tree root microorganisms increased in both periods. …

Phase 1b Study Of Batiraxcept In Combination With Durvalumab In Patients With Platinum-Resistant Ovarian Cancer, Anne Knisely, Emily M Hinchcliff, Elisabeth Gardiner, Reshma Rangwala, Kathryn Lito, Bryan Fellman, Ying Yuan, Anil K Sood, Shannon N Westin, Karen H Lu, Amir A Jazaeri

Faculty, Staff and Student Publications

Combining an immune checkpoint inhibitor with batiraxcept (AVB-S6-500), an AXL inhibitor that acts via selective binding to growth arrest-specific protein 6 (GAS6), may improve anti-tumor immunity in platinum-resistant ovarian cancer (PROC). This phase 1b trial of durvalumab in combination with escalating doses of batiraxcept enrolled patients with recurrent PROC (NCT04019288). The primary objective was to determine the toxicity profile of the combination. Eleven patients were enrolled on the trial. No dose-limiting toxicities were observed, and no objective responses were noted. Median progression free survival (PFS) was 1.81 months (95% confidence interval (CI) 1.71–2.40), and median overall survival (OS) was 4.53 …

Dynamic Visual Acuity, Vestibulo-Ocular Reflex, And Visual Field In National Football League (Nfl) Officiating: Physiology And Visualization Engineering For 3d Virtual On-Field Training, Joshua Ong, Nicole V Carrabba, Ethan Waisberg, Nasif Zaman, Hamza Memon, Nicholas Panzo, Virginia A Lee, Prithul Sarker, Ashtyn Z Vogt, Noor Laylani, Alireza Tavakkoli, Andrew G Lee

Faculty, Staff and Student Publications

The ability to make on-field, split-second decisions is critical for National Football League (NFL) game officials. Multiple principles in visual function are critical for accuracy and precision of these play calls, including foveation time and unobstructed line of sight, static visual acuity, dynamic visual acuity, vestibulo-ocular reflex, and sufficient visual field. Prior research has shown that a standardized curriculum in these neuro-ophthalmic principles have demonstrated validity and self-rated improvements in understanding, confidence, and likelihood of future utilization by NFL game officials to maximize visual performance during officiating. Virtual reality technology may also be able to help optimize understandings of specific …

Low Hunting Costs In An Expensive Marine Mammal Predator, Laia Rojano-Doñate, Jonas Teilmann, Danuta M. Wisniewska, Frants H. Jensen, Ursula Siebert, Birgitte I. Mcdonald, Siri L. Elmegaard, Signe Sveegaard, Rune Dietz, Mark Johnson, Peter T. Madsen

Faculty Research, Scholarly, and Creative Activity

Many large terrestrial mammalian predators use energy-intensive, high-risk, high-gain strategies to pursue large, high-quality prey. However, similar-sized marine mammal predators with even higher field metabolic rates (FMRs) consistently target prey three to six orders of magnitude smaller than themselves. Here, we address the question of how these active and expensive marine mammal predators can gain sufficient energy from consistently targeting small prey during breath-hold dives. Using harbor porpoises as model organisms, we show that hunting small aquatic prey is energetically cheap (<20% increase in FMR) for these marine predators, but it requires them to spend a large proportion (>60%) of time foraging. We conclude that this grazing foraging strategy on small prey is viable for marine …

The Avialan Fauna Of The Late Cretaceous Prince Creek Formation, Alaska, Lauren N. Wilson

Geosciences

Modern polar regions are critical breeding grounds for over 250 species of birds. Some migrate to high latitudes for access to seasonally abundant resources during reproductive periods, whereas others are year-round residents. Despite the major role these birds play in polar ecosystems, we know very little of the origins of the utilization of polar ecosystems for nesting due to the rarity of avialan fossils from high latitudes. The avialan fossil record spans 150 million years, yet evidence for high-latitude bird reproduction extends only to the Eocene La Meseta Formation of Antarctica (56-33.6 Ma). Here, we report a remarkable polar avifauna …

The Impact Of Behavior Change Counseling Delivered Via A Digital Health Tool Versus Routine Care Among Adolescents With Obesity: Pilot Randomized Feasibility Study, Maura Kepper, Callie Walsh-Bailey, Zoe M Miller, Min Zhao, Kianna Zucker, Angeline Gacad, Cynthia Herrick, Neil H White, Ross C Brownson, Randi E Foraker

2020-Current year OA Pubs

BACKGROUND: Youth overweight and obesity is a public health crisis and increases the risk of poor cardiovascular health (CVH) and chronic disease. Health care providers play a key role in weight management, yet few tools exist to support providers in delivering tailored evidence-based behavior change interventions to patients.

OBJECTIVE: The goal of this pilot randomized feasibility study was to determine the feasibility of implementing the Patient-Centered Real-Time Intervention (PREVENT) tool in clinical settings, generate implementation data to inform scale-up, and gather preliminary effectiveness data.

METHODS: A pilot randomized clinical trial was conducted to examine the feasibility, implementation, and preliminary impact …

Liver Acox1 Regulates Levels Of Circulating Lipids That Promote Metabolic Health Through Adipose Remodeling, Dongliang Lu, Anyuan He, Min Tan, Marguerite Mrad, Amal El Daibani, Donghua Hu, Xuejing Liu, Brian Kleiboeker, Tao Che, Fong-Fu Hsu, Monika Bambouskova, Clay F. Semenkovich, Irfan J. Lodhi

2020-Current year OA Pubs

No abstract provided.

Missing Wedge Completion Via Unsupervised Learning With Coordinate Networks, Dave Van Veen, Jesús G Galaz-Montoya, Liyue Shen, Philip Baldwin, Akshay S Chaudhari, Dmitry Lyumkis, Michael F Schmid, Wah Chiu, John Pauly

Faculty, Staff and Students Publications

Cryogenic electron tomography (cryoET) is a powerful tool in structural biology, enabling detailed 3D imaging of biological specimens at a resolution of nanometers. Despite its potential, cryoET faces challenges such as the missing wedge problem, which limits reconstruction quality due to incomplete data collection angles. Recently, supervised deep learning methods leveraging convolutional neural networks (CNNs) have considerably addressed this issue; however, their pretraining requirements render them susceptible to inaccuracies and artifacts, particularly when representative training data is scarce. To overcome these limitations, we introduce a proof-of-concept unsupervised learning approach using coordinate networks (CNs) that optimizes network weights directly against input …

Using An Interrupted Case Study To Engage Undergraduates’ Critical Thinking Style And Enhance Content Knowledge, Kelsey Hall, Katherine Starzec

Journal on Empowering Teaching Excellence

Access the online Pressbooks version of this article here.

The interrupted case study is a structured way to engage students in active learning. Interruptions, or pauses for reflection and discussion scheduled within the case-study presentation, provide students with a chance to collaborate and engage in critical thinking. Critical thinking style, which is a measure of how one tends to think critically, provides insight into how one tackles problem solving. This article describes a pilot project that combined critical-thinking style and an interrupted case study, delivered over a two-class-period time frame, to four college courses. The project’s goals were to assess …

Jrw Spring 2024 Volume 10 Issue 1

Journal of Response to Writing

No abstract provided.

Generous Audience, Activist, Evaluator: Tutor-Teachers’ Knowledge, Practices, And Values For Response To Writing, Carolyn Wisniewski

Journal of Response to Writing

The relationship between tutoring and teaching has been a recurrent topic of interest among writing center directors and writing program administrators. While scholarship agrees tutoring experience aids composition teachers with implementing process pedagogy and fostering a collaborative classroom, the relationship between tutoring and assessment of student writing is less clear. This qualitative study uses interviews with eight graduate teaching assistants with tutoring experience to examine how they transfer and juxtapose knowledge, practices, and values for response between the writing center and classroom. Like previous scholarship, this research finds writing center tutoring contributes to teachers’ enactment of constructivist, student-centered pedagogy and …

Exploring The Evolution Of Altruistic Punishment Using A Pde Model For Multilevel Selection, Daniel Cooney

Biology and Medicine Through Mathematics Conference

No abstract provided.

Identifiability Analysis And Model Reduction For Soft Tissue Models, Mansoor A. Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Perceptual Grouping With Latent Noise, Ben Lonnqvist, Zhengqing Wu, Michael H. Herzog

MODVIS Workshop

Humans effortlessly group elements into objects and segment them from the background and other objects without supervision. For example, the black and white stripes of a zebra are grouped together despite vastly different colors. A thorough theoretical and empirical account of perceptual grouping is still missing – Deep Neural Networks (DNNs), which are considered leading models of the visual system still regularly fail at simplistic perceptual grouping tasks. Here, we propose a counterintuitive unsupervised computational approach to perceptual grouping and segmentation: that they arise because of neural noise, rather than in spite of it. We show that adding noise in …

Anisotropy In Non-Rigidity Perception: The Role Of Anisotropies In Neural Populations, Akihito Maruya, Qasim Zaidi

MODVIS Workshop

No abstract provided.

Tracking Food Quality In Algae-Daphnia Ecosystems Through Stage Structured Models And Colimitation, Tomas Ascoli

Biology and Medicine Through Mathematics Conference

No abstract provided.

Identifiability For Pde Models Of Fluorescence Microscopy Experiments, Veronica Ciocanel

Biology and Medicine Through Mathematics Conference

No abstract provided.

Land Use Intensification And Bio-Resource Utilisation In The South Pacific Islands, David Lopez Cornelio

International Journal of Islands Research

The long and gradual colonisation of the Pacific islands created settlements of cohesive social networks that fused or were displaced by western ways of life, trade and governance through the centuries. In this paper, a historical review of the processes of island discovery, plants domestication, and of land use practices are discussed alongside the main socioeconomic drivers of land cover change. The native trees of the South Pacific constitute an invaluable resource for sustainable development; they were used and domesticated for thousands of years but logging, commercial agriculture, mining, the introduction of exotic species and urban expansion are threatening them …

Analysis Of Poroelastic Systems Describing Biological Tissues, Ellie Gurvich

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Genomics Driven Induced Pluripotent Stem Cell Model Of Infant Acute Lymphoblastic Leukemia - Early Results, Meagan Vacek, Jacqelyn Nemechek, Irina Pushel, Bradley Thornton, Molly Leyda, Priyanka Prem Kumar, Midhat Farooqi, Jay L. Vivian, Erin M. Guest, John M. Perry

Research Days

While the cure rates for pediatric ALL have improved over the decades, infants with ALL (iALL) have not benefitted from these advances and continue to have a devastating prognosis. Unfortunately progress in treatment has also been slowed by inadequate research models. With this project, we address this unmet need by investigating a novel model to understand the cellular and molecular changes that occur during iALL onset and progression.

Multiscale Modeling Of Microtubule Polarity Mechanisms Following Neuronal Axotomy, Hannah Scanlon

Biology and Medicine Through Mathematics Conference

No abstract provided.