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Breaking The Silence: Autoethnographic Account Of Communication In The Aftermath Of Parental Suicide, Marissa L. Lucero

Communication ETDs

The silence that surrounds the suicide of a parent often masks unresolved feelings of guilt, shame, and powerlessness in families grieving their loss. For children, the long-lasting impact of suppressing communication about parental suicide can endure throughout adulthood. In this autoethnography, I un-salience my voice to reflect on my father’s suicide in the context of my Nuevo Mexicana identity. I assert my Chicana feminist voice through an extraction of gendered and culturally grounded memories, personal journal entries from my childhood, and a review of academic sources on suicide. This thesis is a personal and intellectual engagement with Chicana/o critical theory, …

Cardiovascular Disease In Adults With A History Of Out-Of-Home Care During Childhood: A Systematic Review And Meta-Analysis Of Prospective Cohort Studies, G. David Batty, Mika Kivimäki, Ylva B. Almquist, Johan G. Eriksson, Mika Gissler, Emmanuel S. Gnanamanickam, Mark Hamer, Josephine Jackisch, Hee-Soon Juon, Markus Keski-Säntti, Chaiquan Li, Tuija M. Mikkola, Emily Murray, Amanda Sacker, Leonie Segal, Philipp Frank

Department of Medical Oncology Faculty Papers

Background

While individuals who were separated from their biological family and placed into the care of the state during childhood (out-of-home care) are more prone to developing selected adverse health problems in adulthood, their risk of cardiovascular disease is uncertain. Our aim was to explore this association by pooling published and unpublished results from prospective cohort studies.

Methods

We used two approaches to identifying relevant data on childhood care and adult cardiovascular disease (PROSPERO registration CRD42021254665). First, to locate published studies, we searched PubMed (Medline) until November 2023. Second, with the objective of identifying unpublished studies with the potential to …

A Fungal Metabolic Regulator Underlies Infectious Synergism During Candida Albicans-Staphylococcus Aureus Intra-Abdominal Co-Infection, Saikat Paul, Olivia A. Todd, Kara R. Eichelberger, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, James E. Cassat, Paul L. Fidel, Brian M. Peters

School of Dentistry Faculty Publications

Candida albicans and Staphylococcus aureus are two commonly associated pathogens that cause nosocomial infections with high morbidity and mortality. Our prior and current work using a murine model of polymicrobial intra-abdominal infection (IAI) demonstrates that synergistic lethality is driven by Candida-induced upregulation of functional S. aureus α-toxin leading to polymicrobial sepsis and organ damage. In order to determine the candidal effector(s) mediating enhanced virulence, an unbiased screen of C. albicans transcription factor mutants was undertaken revealing that zcf13Δ/Δ fails to drive augmented α-toxin or lethal synergism during co-infection. A combination of transcriptional and phenotypic profiling approaches shows that ZCF13 regulates …

Revealing Structural Evolution Of Nickel Phosphide-Iron Oxide Core–Shell Nanocatalysts In Alkaline Medium For The Oxygen Evolution Reaction, Ryan H. Manso, Jiyun Hong, Wei Wang, Prashant Acharya, Adam S. Hoffman, Xiao Tong, Feng Wang, Lauren F. Greenlee, Yimei Zhu, Simon R. Bare, Jingyi Chen

Chemistry & Biochemistry Faculty Publications and Presentations

Metal phosphide-containing materials have emerged as a potential candidate of nonprecious metal-based catalysts for alkaline oxygen evolution reaction (OER). While it is known that metal phosphide undergoes structural evolution, considerable debate persists regarding the effects of dynamics on the surface activation and morphological stability of the catalysts. In this study, we synthesize NiP_x-FeO_x core–shell nanocatalysts with an amorphous NiP_x core designed for enhanced OER activity. Using ex situ X-ray absorption spectroscopy, we elucidate the local structural changes as a function of the cyclic voltammetry cycles. Our studies suggest that the presence of corner-sharing octahedra in the …

Agenda De Investigación Para El Manejo Sustentable Del Manglar En Tamaulipas, México [Research Agenda For The Sustainable Management Of Mangroves In Tamaulipas, Mexico], Carlos Zamora-Tovar, Alejandro Fierro-Cabo, Glenda Nelly Requena-Lara

School of Earth, Environmental, & Marine Sciences Faculty Publications

Se presenta un análisis de la información ecológica disponible sobre los manglares de Tamaulipas, México. El objetivo fue establecer una línea base de conocimiento que defina el estado del arte a partir de la información publicada; actualizar la estructura forestal con datos propios observados en el año 2018; y determinar una agenda de investigación prioritaria para el manejo sostenible del ecosistema de man-glar, ecosistema de vital importancia por la gran variedad de recursos y servicios ambientales que aporta a la sociedad. La investigación bibliográfica recopiló 32 trabajos relevantes: 16 publicaciones formales, siete ediciones institucionales y nueve consideradas literaturas gris; recopilación …

Identification Of An H-Ras Nanocluster Disrupting Peptide, Candy Laura Steffen, Ganesh Babu Manoharan, Karolina Pavic, Alejandro Yeste-Vázquez, Matias Knuuttila, Neha Arora, Yong Zhou, Harri Härmä, Anthoula Gaigneaux, Tom N Grossmann, Daniel Kwaku Abankwa

Faculty, Staff and Student Publications

Hyperactive Ras signalling is found in most cancers. Ras proteins are only active in membrane nanoclusters, which are therefore potential drug targets. We previously showed that the nanocluster scaffold galectin-1 (Gal1) enhances H-Ras nanoclustering via direct interaction with the Ras binding domain (RBD) of Raf. Here, we establish that the B-Raf preference of Gal1 emerges from the divergence of the Raf RBDs at their proposed Gal1-binding interface. We then identify the L5UR peptide, which disrupts this interaction by binding with low micromolar affinity to the B- and C-Raf-RBDs. Its 23-mer core fragment is sufficient to interfere with H-Ras nanoclustering, modulate …

Leukocyte Immunoglobulin-Like Receptor B1 (Lilrb1) Protects Human Multiple Myeloma Cells From Ferroptosis By Maintaining Cholesterol Homeostasis, Miao Xian, Qiang Wang, Liuling Xiao, Ling Zhong, Wei Xiong, Lingqun Ye, Pan Su, Chuanchao Zhang, Yabo Li, Robert Z Orlowski, Fenghuang Zhan, Siddhartha Ganguly, Youli Zu, Jianfei Qian, Qing Yi

Faculty, Staff and Student Publications

Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled proliferation of plasma cells in the bone marrow. MM patients with aggressive progression have poor survival, emphasizing the urgent need for identifying new therapeutic targets. Here, we show that the leukocyte immunoglobulin-like receptor B1 (LILRB1), a transmembrane receptor conducting negative immune response, is a top-ranked gene associated with poor prognosis in MM patients. LILRB1 deficiency inhibits MM progression in vivo by enhancing the ferroptosis of MM cells. Mechanistic studies reveal that LILRB1 forms a complex with the low-density lipoprotein receptor (LDLR) and LDLR adapter protein 1 (LDLRAP1) to facilitate LDL/cholesterol …

The History Of Diapers And Their Environmental Impact, Cansu Tokat, Nicholas C. Rickman, Cynthia F. Bearer

Faculty Scholarship

Impact: This article examines diaper practices around the world throughout history. This article reviews the innovation of the modern diaper and the environmental effects of disposable diapers.

Attenuating Midline Thalamus Bursting To Mitigate Absence Epilepsy, Ping Dong, Konstantin Bakhurin, Yuhui Li, Mohamad A Mikati, Jianmin Cui, Warren M Grill, Henry H Yin, Huanghe Yang

2020-Current year OA Pubs

Advancing the mechanistic understanding of absence epilepsy is crucial for developing new therapeutics, especially for patients unresponsive to current treatments. Utilizing a recently developed mouse model of absence epilepsy carrying the BK gain-of-function channelopathy D434G, here we report that attenuating the burst firing of midline thalamus (MLT) neurons effectively prevents absence seizures. We found that enhanced BK channel activity in the BK-D434G MLT neurons promotes synchronized bursting during the ictal phase of absence seizures. Modulating MLT neurons through pharmacological reagents, optogenetic stimulation, or deep brain stimulation effectively attenuates burst firing, leading to reduced absence seizure frequency and increased vigilance. Additionally, …

Utilizing Biosimilars To Help Increase Patients Access And Minimize The Financial Burden Of Health Care System In Egypt, Doaa M. Abd-El-Rady, Iman A. El-Baraky, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Background: Biologics have provided enhanced clinical advantages, but at expense of enormous expenditures. The exorbitant expense of biologics was somewhat mitigated by the development of biosimilars. But biosimilars market access is still recessed in many countries including Egypt. To achieve biosimilars market sustainability, countries need to evaluate the health economic barriers that biosimilars face in gaining market access.

Methods: A retrospective budget impact analysis was conducted to compare the cost of biosimilars to that of their reference biologics from Egyptian regulatory perspective over a five-year period (2018-2022). Time series forecasting analysis was conducted to predict the cost savings …

Removal Of Textile Dyes By Ecofriendly Aquatic Plants From Wastewater: A Review On Plants Species, Mechanisms, And Perspectives, Manal M. El-Sadaawy, Nancy S. Agib

Blue Economy

Water, an essential resource for sustaining life on our planet, is crucial for both human beings and the overall ecosystem. However, in recent decades, several factors, including population growth, rapid industrialization, urbanization, and unsustainable utilization of natural resources, have significantly impacted the quality of water. Industries such as textiles, leather tanning, cosmetics, and pigmentation extensively employ colored compounds called dyes for various purposes. Synthetic dyes have largely replaced natural dyes due to their superior durability against washing, heat, light, pH, and exposure to biological agents. Azo dyes, sulfur dyes, and pigment dyes are some examples of dyes used in industrial …

Live-Weight Gain Of Steers Grazing African Star Grass Four Herbage Allowances, J Perez-Perez, J O. Hernandez-Velez, J G. Herrera-Haro, R Barcena-Gama

IGC Proceedings (1977-2023)

The objective was to determine weight changes of steers grazing African star grass (Cynodon plectostachyus) at four herbage allowances (2.0, 2.5, 3.0 and 3.5 kg of dry matter/100 kg of live weight day-1). A rotational grazing system with 10 grazing days and 30 days rest was followed. A Split Plot Design with four replications was used. Response variables were: daily gain per steer (DGS) and per hectare (DGH), dry matter forage yield (FY), % of utilization (% U) and in vitro dry matter digestibility (DMIVD). DGS and DGH were not different (P >0.05) among allowances and grazing periods. …

Strategic Use Of Brachiaria Decumbens Pasture To Beef Heifers During Dry Season, E G. Cardoso, N F. Seiffert, J Marques Da Silva, V.P. B. Euclides, J M. Vieira

IGC Proceedings (1977-2023)

The main objective of this study was to evaluate a Brachiaria decumbens pasture, instead of a common rangeland, for zebu beef heifers during the dry season of the year as a means of anticipating the first calving age from four to three years of age, and so improve the production rate of the herd. Daily liveweight gains (DLWG) were analyzed for the effects of year and three stocking rates during the dry season (SR1=1.5; SR2=2.0 and SR3=2.5 head/ha). The main effect on heifers DLWG was the year (P<0.01), but SR was also important (P<0.05), mainly during the last half of the dry season when pastures are under severe constraints such as soil moisture deficit and low temperatures. The lowest SR presented the highest DLWG (0.204a, 0.174ab and 0.145b kg/head, respectively for SR1, SR2 and SR3), during the dry season. If climatic conditions are not exceptionally bad, heifer first calving occurs at 37 months of age when reared on B. decumbens.

Quality Grassland For Dairy Production In North-West Spain, A Gonzalez-Rodriguez

IGC Proceedings (1977-2023)

An experiment with two groups of 15 Friesian cows grazing independent areas, with no N and 240 kg N ha-1, was run during two years to see the levels of milk production based on a grass/white clover pasture, maintaining high levels of herbage quality. N application decrease clover content from 55% to 42%. The total DM response to N was low. Herbage utilization was maintained similar in both treatments. Moderate levels of milk production can be reached, more than 4000 litres cow-1 and 9000 litres ha-1, with low use of concentrates, only 400 kg cow-1. Crude protein levels were high …

Sward Height On The Performance Of Cow-Calf Units And Yearling Steers Grazing Cool Season Pasture, E C. Prigge, W B. Bryan, E L. Nestor

IGC Proceedings (1977-2023)

Performance and grazing time of cow-calf units and yearling steers were determined over four years on naturalized cool season pastures maintained at a sward height of 4-6, 6-8, 8-10, or 10-12 cm. Daily gains of cows and steers responded quadratically (P<0.05) to increasing sward heights, with gains maximized at 8-10 cm. Milk production of the cows and gain of the calves were not affected (P>0.10) by sward height. Grazing days (cow-calf unit/hectare) decreased linearly (P<0.01) with increasing sward height. The proportion of the day spent grazing for cows and steers decreased in a linear manner (P<0.05) as pasture height increased. Cows spent less time grazing than steers (P<0.05) at all but the low pasture height.

Buffer Grazing For A Twelve Month Cow-Calf Production System, W B. Bryan, E C. Prigge, D J. Flaherty, G E. D'Souza

IGC Proceedings (1977-2023)

Set stocking is a widely used grazing management for beef cow-calf production on Appalachian hill land pastures of the USA. A replicated study was conducted to compare a conventional (set stocking) and buffer grazing management. For the buffer system, grazing area was restricted in the spring and hay was harvested from the ungrazed area. In summer, a portion of this area (buffer) was grazed and a second cutting of hay removed from the remaining area. For the conventional treatment a fixed area was set stocked and hay was harvested on an area designated for hay only. Land areas and fertilizer …

Intensive Rotational Grazing Systems For Dairying In A Subtropical Environment: Animal, Plant, And Soil Responses, J H. Fike, C R. Staples, L E. Sollenberger, D A. Graetz

IGC Proceedings (1977-2023)

Forage species, stocking rate, and supplementation rate effects upon performance of lactating dairy cows were studied. Forage mass and nutritive value and nutrient concentration in shallow groundwater also were measured. Cows (n = 44) grazed bermudagrass (Cynodon dactylon) or rhizoma peanut (Arachis glabrata), stocked at 4.9 or 7.4 cows ha-1, and 2.5 or 4.9 cows ha-1, respectively. Pelleted concentrate:whole cottonseed (80:20) was offered twice daily post milking at 1 kg per 2 or 3 kg of daily milk production. Cows grazing rhizoma peanut produced more (P = .076) milk per day but had greater (P = …

High Moisture Corn Supplementation Of Different Dry Matter Content To Cows Grazing Temperate Pasture, D H. Rearte, H Alvarez, F Santini

IGC Proceedings (1977-2023)

The objective of this study was to evaluate grazing dairy cows performance supplemented with high moisture corn of different dry matter content. Cows grazed fresh forage oat day and night and received 5 kg DM high moisture corn daily. Treatments 1 and 2 were high moisture corn of 30% and 18% moisture content respectively. Twenty Holstein cows were used for milk production and composition studies and six rumen fistulated cows were used for rumen digestion studies. Milk production and composition and body weight gain were not affected by the dry matter content of the supplemented high moisture corn. Related to …

Intake Of High Producing Holstein Cows Grazing Pasture Or Fed A Total Mixed Ration, E S. Kolver, L D. Muller

IGC Proceedings (1977-2023)

The ability of a pasture diet to support a high dry matter intake without supplementary feed was determined using 16 high producing Holstein cows. Cows (n=8) were adapted to an all-pasture diet by incrementally reducing the amount of total mixed ration (TMR) fed over four weeks. A control group of cows (n=8) remained in confinement and were fed a TMR. Performance of grazing cows differed significantly (P < 0.001) from TMR fed cows by intake (19.0 vs. 23.4 kg DM/d), milk production (29.6 vs. 44.1 kg/d), milk protein content (2.61 vs. 2.80%), liveweight (562.1 vs. 597.3 kg), and condition score (2.02 vs. 2.50). Results indicate that intake of good quality pasture is higher than previously estimated for high producing Holstein cows in the USA, but that milk production is 15 kg/d less than when cows are fed a TMR.

Cattle Production And Botanical Composition In Continuously Stocked Grass-Clover Swards, A Elgersma, H Schlepers

IGC Proceedings (1977-2023)

The performance of grass-clover mixtures was evaluated under cattle grazing, and the relations between grass variety, clover content and animal production were studied during four years at three locations. The prostrate diploid perennial ryegrass variety formed a dense sward with less clover and less weeds than the tetraploid or the erect diploid ryegrass varieties, which contained about the same amount of clover in the mixture. The ryegrass tiller density was lowest in the tetraploid. These differences between mixtures were not reflected in differences in animal performance or net energy production.

Production Efficiency Benchmarks For Irrigated Dairying In South Eastern Australia, K E. Pritchard, O A. Gyles, D P. Armstrong, S L. Spiteri

IGC Proceedings (1977-2023)

Milk production from grazed irrigated pasture is an important industry in south eastern Australia. Irrigation water is essential for perennial pastures, but the efficiency with which the irrigation water is used to produce milk varies widely between farms. As irrigation water is a limiting resource, future productivity increases will depend on increasing the amount of milk produced per unit of water applied. This research project estimates metabolisable energy utilised from grazed pasture, using energy values for animal requirements, products and feedstuffs. Efficiency criteria, in terms of production per hectare of irrigated pasture, per megalitre of irrigation water, and per cow …

Grazing Management And Nitrogen Fertilizer Effects In Grazing Systems For Beef Cows, D G. Morrison, C C. Willis, D L. Castle, G J. Cuomo

IGC Proceedings (1977-2023)

Four 8-ha areas, primarily Cynodon dactylon forage, were overseeded in autumn with annual ryegrass (Lolium multiflorum) and clover (Trifolium incarnatum and Trifolium repens). Two areas received no nitrogen (N) fertilizer and two received 168 kg N/ha annually. Within N level (2 x 2 factorial), one area was divided into 4 paddocks (pad) and the other into 16 pad for rotational grazing. Spring-calving beef cows were stocked (2.5/ha) year-round on each area with calves weaned in October. Annual dry matter forage accumulation was greater where N was applied (18.2 vs 14.2 Mg/ha, P=.02) but was unaffected by …

Sheep Production On An Annual And Perennial Pasture In Southwest Australia, P Sanford, J Gladman, L Cransberg

IGC Proceedings (1977-2023)

Sheep production on an annual and perennial pasture stocked at 11.5 dse/ha, was compared in a mediterranen environment at Manypeaks in Western Australia. The annual sward comprised of 48% subterranean clover (Trifolium subterraneum L.), 20 % annual grasses (Lolium rigidum Gaudin, Hordeum leporinum Link, Vulpia bromoides (L.) S.F. Gray) and 32% capeweed (Arctotheca calendula L.). The perennial sward was 19% kikuyu (Pennisetum clandestinum), 36% subterranean clover, 43% annual grasses (Lolium rigidum Gaudin, Hordeum leporinum Link, Vulpia bromoides (L.) S.F. Gray) and only 2% capeweed which was displaced by kikuyu. Both pasture types had similar growth …

Milk Production And Composition In Charolais And Polled Hereford Cows On Different Forage Systems, J M. Phillips, R B. Simpson, J D. Shockey, S C. Nickerson

IGC Proceedings (1977-2023)

The objective of this study was to study the effect of different winter and summer forage systems on milk production and composition in beef cows. Charolais and Polled Hereford cows were assigned to receive either grass hay and supplemental feed or ryegrass pasture during the late winter/early spring period, and then allowed to either graze warmseason grass pasture on a continuous or rotational basis during the summer period. Representative cows were machine-milked on day 48 (hay/feed vs ryegrass), on days 117 and 175 (continuous vs rotational grazing) postpartum. Milk weights were recorded and converted to 24- hour yields. Samples were …

Intensive Grazing Management For Dairy Heifers, J R. Rodgers

IGC Proceedings (1977-2023)

After grazing our milking herd on intensive rotational grazing for three years utilizing many paddocks and different types and configurations of fencing to control the wise use of the grass and legume species already on our farm, we moved to develop our second farm into a commercial heifer growing project. This paper will attempt to share our practical experience through three years of grazing upwards of 400 Ayrshire and Holstein heifers from six months of age until just prior to calving. Our ultimate objective is year end financial solvency.

Pasture Production And Weaned Heifer Performance From Tropical Grasses, P Mislevy, F M. Pate, F G. Martin, L M. Rutter

IGC Proceedings (1977-2023)

The purpose of this experiment is to determine the influence of energy supplement (molasses 80% and cottonseed meal 20% slurry) fed to heifers while grazing Florico and Florona stargrass (Cynodon nlemfuensis Vanderyst var nlemfuensis) and Florakirk bermudagrass (C. dactylon) pastures. Stocking rate of heifers was 5.9 animals ha- 1 averaging 230 kg. Heifers were rotated weekly and were on a 4 pasture rotation. Grasses were allowed a 3-wk regrowth period. Mean forage growth rate cycle-1 day-1 was not different (P>0.05) between grasses; however Florico and Florona yielded 8 and 21% more cycle- 1 than Florakirk. Mean herbage …

Seasonal Distribution Of Forage Yield From A "Natural" Pasture Under Rotational Grazing, W R. Kanneganti, T R. Dhiman, R P. Walgenbach, L Massingill, M P. Russelle, L D. Satter

IGC Proceedings (1977-2023)

A 2-yr grazing study was conducted to quantify forage available daily for cattle intake from a natural pasture managed under rotational grazing. Grazing was initiated around 1 May, and was managed with a rotation length of about 17 d each for cycles 1 and 2, and 30 d each for the rest. In 1994, under adequate moisture conditions, forage availability during 5/1-6/1, 6/1-8/15, 8/15-9/15, and 9/15-10/ 15 was 77, 66, 38 and 14 kg DM ha-1 d-1, respectively, resulting in a total yield of 8580 kg ha-1 in 175 d. In 1995, a prolonged period of dry summer reduced the …

Production Response To Feed Supplementation Of Dairy Cows In A Seasonal Calving And Grazing System, T R. Dhiman, W R. Kanneganti, R P. Walgenbach, L J. Massingill, M C. Miltbank, M P. Russelle, L D. Satter

IGC Proceedings (1977-2023)

A study was conducted over a period of two years to determine the impact of supplemental feed on milk yield and reproductive performance of dairy cows in a spring calving and grazing system. Three groups of Holstein cows consumed either all pasture (P), 2/3 (2/3P), or 1/3 (1/3P) of their feed dry matter from a temperate pasture of mixed grasses and white clover (Trifolium repens L.). The balance of feed for the 2/3P and 1/3P groups was supplied by a supplement containing grain and some forage. Cows calved between March and June. During the grazing season cows consumed 0, 5.8 …

The Effect Of Turnout Date To Pasture In Spring And Grazing Strategy On The Performance Of Spring-Calving Dairy Cows In Wet Land Enviornment, J Maher, S Crosse, M Rath

IGC Proceedings (1977-2023)

The objective was to investigate the effect of earlier turnout to pasture in spring on animal performance in a wet land environment. Fiftysix spring-calving dairy cows were randomly allocated to four treatments and the stocking rate for each treatment was 2.47 cows/ ha. Cows in three of these treatments commenced grazing in mid- March. The cows on Treatment A grazed 100% of the farm and received 3 kg/day of concentrate. Cows on Treatment B and C grazed 50% of the farm (area designated for silage production), received silage at night, indoors, and 6 kg/day and 3 kg/day of concentrate respectively. …

Managing A Multi-Forage Rotational Stocking Unit Without Farming Equipment And With The Addition Of Economical Fringe Benefits, R L. Dalrymple, B C. Flatt, F W. Dobbs, J A. Barrick

IGC Proceedings (1977-2023)

A specialized introduced forage rotational stocking grazing unit was managed without usual grassland farming equipment and with various alternative management and production techniques as fringe benefits. The forage production techniques have been successful for many years. Livestock production and economic perimeters have been average to above average. The greatest sold beef yield has been 713 pounds of beef per acre. That is excellent considering the low-capital overhead management style of the unit.