Digital Commons Network^™

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Relationship Between Functional Status And Fatigue After Covid-19 Infection: A Multicenter Study From Türkiye, İpek Candemi̇r, Pinar Ergün, Di̇cle Kaymaz, Mustafa Engi̇n Şahi̇n, İpek Özmen, Eli̇f Yildirim, Asli Görek Di̇lektaşli, Büşra Yi̇ği̇tli̇ler, Ayten Odabaş, Deni̇z Kizilirmak, Seçi̇l Sari, Celaletti̇n Korkmaz, Cantürk Taşçi, Yakup Arslan, Sema Savci, Buse Kahraman, Ayli̇n Tanriverdi̇, Can Sevi̇nç, Melda Sağlam, Deni̇z İnal İnce, Naci̇ye Vardar Yağli, Ebru Kütükçü, Di̇lber Durmaz, Nesli̇han Durutürk, Gaye Ulubay, Lütfi̇ye Kiliç, Benan Çağlayan, Ayli̇n Moray, Sabri̇ Serhan Olcay, Güven Özkaya

Turkish Journal of Medical Sciences

Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence …

Turkish Adaptation Of The Neonatal Eating Assessment Tool–Bottle-Feeding In Preterm Infants Discharged To Home, Burcu Aykanat Gi̇rgi̇n, Duygu Gözen, Sabi̇ha Çağlayan, Bri̇tt Pados

Turkish Journal of Medical Sciences

Background/aim: Preterm infants often continue to have feeding difficulties after hospital discharge. Parental use of assessment tools and collaboration with health professionals are important for the early diagnosis of post-discharge feeding difficulties. This methodological study examined the validity and reliability of the Turkish version of the Neonatal Eating Assessment Tool (NeoEAT)–Bottle-feeding in post-discharge preterm infants in Turkey.Materials and methods: A Turkish version of the NeoEAT–Bottle-feeding was developed and applied to 321 mothers of preterm infants younger than seven months of corrected age between August 2021 and December 2022. Cronbach’s α, exploratory factor, confirmatory factor, item-total correlation, test-retest, and known-groups validity …

Correlation Between Plasma Ccfdna, Mtdna Changes, Ctcs, And Epithelial-Mesenchymal Transition In Breast Cancer Patients Undergoing Nact, Betül Çeli̇k, İrem Peker Eyüboğlu, Si̇nan Koca, Mustafa Ümi̇t Uğurlu, Özkan Alan, Gökçe Güllü Amuran, Tuğba Akin Telli̇, Fulden Yumuk, Mustafa Akki̇pri̇k

Turkish Journal of Medical Sciences

Background/aim: Breast cancer is the most prevalent cancer in women, emphasizing need for noninvasive blood biomarkers to aid in treatment selection. Previous studies have demonstrated elevated levels of plasma circulating cell-free DNA (ccfDNA) in breast cancer patients. Both ccfDNA and mitochondrial DNA (mtDNA) are fragments released into the bloodstream. In this study, we investigated effectiveness of ccfDNA and mtDNA as indicators of treatment response and explored their potential as monitoring biomarkers. Additionally, we compared these markers with circulating tumor cell (CTC) data and assessed their relationship with epithelial-mesenchymal transition (EMT).Materials and methods: Thirty-six female breast cancer patients and 21 healthy …

Investigation Of The Status Of Immune Checkpoint Molecules (Pd-L1 And Pd-1) In Meningiomas By Immunohistochemistry, İsmai̇l Saygin, Emel Çakir, Seher Nazli Kazaz, Ali̇ Riza Güverci̇n, İlker Eyüpoğlu, Müşerref Müge Ustaoğlu

Turkish Journal of Medical Sciences

Background/aim : Meningiomas are the most common primary brain tumors of the central nervous system. Immunotherapy is a promising treatment method applied in many types of cancer. There is no standard and effective medical treatment to reduce recurrence and mortality in cases of incomplete resection of meningiomas and in high-grade cases. In order to investigate medical treatments in addition to surgery and radiotherapy, in this study, the status of immune checkpoint molecules (PD-L1/PD-1), which are the target of immunotherapy, in meningiomas was investigated.Materials and Methods: Four hundred two cases of meningioma diagnosed between 2007 and 2020 in our institution were …

The Sharp Edge Of Immunosuppressive Treatments: Infections, Aybegüm Özşahi̇n, Tuba İlgar, Sudem Mahmutoğlu Çolak, Kübra Akyüz, Meli̇h Gaffar Gözükara, Uğur Kostakoğlu, İlknur Esen Yildiz, Ayşe Ertürk

Turkish Journal of Medical Sciences

Background and aim: Different side effects, including infections, are encountered in patients receiving anticytokines used for the treatment of severe coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the infections and the effects of these infections that develop in this patient group. Materials and Methods: This study included 208 patients who were followed-up with the diagnosis of severe COVID-19 in two different hospitals. Patient data were obtained retrospectively from the hospital information system. Results: Of the 208 patients included, 54 were in the anakinra group, and 154 were in the tocilizumab group. Of these patients, 73 …

Distal Interphalangeal Joint Involvement In Patients With Rheumatoid Arthritis: Where Are We?, Mete Pekdi̇ker, Sertaç Ketenci̇, Gökhan Sargin

Turkish Journal of Medical Sciences

Background/aim: Rheumatoid arthritis (RA) usually affects the wrist, metacarpophalangeal joint, and proximal interphalangeal joint of the hands. However, the distal interphalangeal (DIP) joints may also be involved in RA patients. In this study, we aimed to evaluate the frequency and associated factors of DIP joint erosion in patients with RA.Materials and methods: Medical records of patients with RA were reviewed retrospectively. Patients with major trauma affecting DIP joints, osteoarthritis, erosive osteoarthritis, psoriatic arthritis, systemic sclerosis, calcium pyrophosphate dihydrate disease, and gout were excluded. Anteroposterior hand X-rays were evaluated and patients were divided into groups according to autoantibody profile.Results: We reviewed …

Effect Of Vascularized Jejunal Conduit Flap On Peripheral Nerve Regeneration In Rats, Maji̇d Ismayilzade, Bi̇lsev Ince, Pembe Oltulu, Zi̇krullah Baycar, Münür Selçuk Kendi̇r, Mehmet Dadaci

Turkish Journal of Medical Sciences

Background/ Aim: In the literature, almost all of the propounded nerve conduits for obtaining better nerve recovery were applied as graft materials. In this study, we aimed to define a new nerve conduit model in a flap pattern and evaluate the effect of pedicled vascularized jejunal flap on nerve regeneration after wrapping around a sciatic nerve.Materials and Methods: A total of 90 Wistar albino rats were randomly divided into nine groups each with 10 rats. The first three groups constituted the control groups, whereas groups 4-6 were the jejunum conduit (JC) - applied groups. A mucosa resected JC (MRJC) was …

Nnmt Overexpression Is An Adverse Prognostic Factor In Uterine Leiomyosarcoma, Osman Türkmen, Kami̇l Hakan Müftüoğlu, Nazmi̇ye Di̇nçer, Zeli̇ha Esi̇n Çeli̇k, Serra Akar İnan

Turkish Journal of Medical Sciences

Background/Aim: Uterine leiomyosarcomas (uLMS) are extremely rare high-grade tumors with a poor prognosis. Their etiopathogenesis remains largely unknown. The uterus is the most frequent site for LMS. uLMS and uterine leiomyoma (uLM) must frequently be differentiated in patients with a uterine mass. Nicotinamide N-methyltransferase (NNMT), a cytoplasmic protein, is involved in the progression and spread of a variety of cancer types. The expression of NNMT in a mesenchymal malignancy was not examined previously. This study represents the first investigation into NNMT expression in uLMS, uLM and benign uterine myometrium and correlates NNMT overexpression with worse prognosis in uLMS. Materials/Methods: The …

Chlorogenic Acid Ameliorates Memory Dysfunction Via Attenuating Frontal Lobe Oxidative Stress And Apoptosis In Diabetic Rat Model, Ramedhea Laila Afifa An Nur Willya Saputri, Nur Arfian, Junaedy Yunus, Fauziyatul Munawaroh, Sagita Mega Sekar Kencana, Dwi Cayhani Ratna Sari

Turkish Journal of Medical Sciences

Background/aim: Diabetes mellitus, characterized by hyperglycemia, causes various complications, one of which is memory dysfunction. The frontal lobe is known to be responsible for impaired memory function due to hyperglycemia and is associated with oxidative stressmediated neuronal cell apoptosis. Chlorogenic acid (CGA) is reported to have neuroprotective effects. However, its effect on the frontal lobe in diabetes mellitus (DM) rats is not widely known. This research aimed to elucidate the effect of CGA on the mRNA expressions of SOD1, SOD2, p53, and Bcl-2 in the frontal lobe of DM rats. Materials and methods: Thirty male Wistar rats (2-month-old, 150–200 gBW) …

Muscle Damage And Immune-Endocrine Responses In 20km Walking Race, Bruno Marques Fidelis, Julio C. Molina Correa, Martim G. Weber, Matheus G. Gois, Solange De Paula Ramos, Eduardo C F Tonani

International Journal of Exercise Science

International Journal of Exercise Science 17(7): 1167-1182, 2024. The objective of the study was to monitor exercise-induced muscle damage (EIMD), inflammatory responses (IL-6, TNFα, and IL-10), and immune-endocrine balance (testosterone, cortisol, and salivary SIgA) in official 20 km walking race competitions. Eight 20 km professional walking racers (n = 6 women), 27 ± 9 years, underwent blood and saliva sampling, evaluation of delayed-onset muscle soreness (DOMS), and squat (SJ) and countermovement (CMJ) jump tests 2 h before (Pre), immediately after (Post), and 24 and 48 h after the competition. The rate of perceived exertion (RPE) was recorded 20 minutes …

Finding Common (Moral) Ground In Critical Service Learning: Promoting Balance And Civil Discourse Through Moral Foundations Theory, James Morgan Lewing

Journal of Community Engagement and Higher Education

Critical approaches to service learning courses may not innately maximize student engagement, civil discourse, and the confrontation of stereotypes. The purpose of this article is to propose the utilization of Moral Foundations Theory as a complimentary framework for service learning courses seeking to critically analyze systems and policies. Recommendations for practice and future research are included.

Graduate And Undergraduate Student Development As A Result Of Participation In A Grief Education Service Learning Course, Laura S. Wheat, Arden Szepe, Nathan B. West, Melinda M. Gibbons

Journal of Community Engagement and Higher Education

Limited research exists on the role service learning can play in helping students understand loss and grief. Through semi-structured interviews with students and instructors, online surveys, and course feedback, this qualitative case study examined the experiences of 15 university students in an outreach course working with grieving K-12 students. Students self-reported gaining greater intra- and interpersonal understanding and grief processing self-efficacy. Instructors emphasized intentionality and the intertwined nature of course experiences influencing meaning making.

Pursuing Reciprocity In Engaged Scholarship Partnerships Using Community Sustainability Certification Programs, Elyzabeth W. Engle, Michele W. Halsell

Journal of Community Engagement and Higher Education

In recent years, there has been a proliferation of sustainability certification programs at the local, state, and national level to highlight the use of policies, programs, and infrastructure to achieve sustainable development outcomes within communities. In this paper, we use examples from Penn State’s Sustainable Communities Collaborative to demonstrate how institutions with community-engaged scholarship programs can use these certification programs to enhance program operation and reciprocity by identifying projects, engaging new disciplines, and improving relevance.

Social And Cognitive Outcomes Of Service Learning: Results From A Pre-Post And Control Group Comparison, Rebecca G. Ryan

Journal of Community Engagement and Higher Education

Students in an undergraduate course opted to either complete a service-learning project or write article summary papers over the course of a semester. Analyses revealed a significant increase in aspects of empathy, social responsibility, and community and personal involvement in the service-learning group, but not in the control group. The findings are discussed in terms of the social and cognitive benefits of service learning and considerations for incorporating service learning into a gerontology-related course.

Service Learning For The Port Jefferson History And Nature Center: Senior Capstone Forestry Course, David L. Kulhavy, Daniel Unger, Ryan Grisham, Gary Endlsey

Journal of Community Engagement and Higher Education

A community partnership between the Collins Academy, Jefferson, Texas, and the Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, Texas, developed a plan to manage the 38-acre Port Jefferson History and Nature Center, located on Big Cypress Bayou. Students used knowledge of the resources, GPS (global positioning systems), ArcGIS 10.4, presentations, and posters to complete the project. The reflection and feedback with the community partners continued throughout the project and as guidance for future work. This partnership instilled in participating students the value of incorporating service learning into development of professional relationships for continued cooperation …

Enhancing Learning, Changing The World: How Service-Learning Influences The Brain, Tracey Honeycutt Sigler, Kristi Lewis Tyran

Journal of Community Engagement and Higher Education

Service-learning helps students learn about course concepts through applying them in a setting outside the classroom. The experiences provided by service-learning create conditions that can lead to changes in the learner’s brain. In this paper, we provide support for this assertion from research in brain-based learning with suggestions of how to explicitly apply concepts from these areas of study to service-learning pedagogy so that we might increase learning.

Maintaining Engaged Scholarship In Challenging Times: Experiences Working With Veteran Medical Providers In Greater Los Angeles, Angela Chalé, Elizabeth Avila, Yvette Avila, Christina Chalé

Journal of Community Engagement and Higher Education

This paper describes the challenges experienced in a study premised on scholarly engagement that consisted of a partnership between the nutritional science program and medical providers at the Veterans Administration, Greater Los Angeles, following allegations of systemic misconduct in the delivery of health care by the Veterans Health Administration (VHA). Since the VHA is a primary provider of medical training in the United States, we were interested in obtaining their opinion about and knowledge of vitamin D nutriture in relation to cognitive and physical functioning. We were unable to overcome challenges that undermined collaboration and propose incentivization, partnering with grounded …

Faculty Feel It Too: The Emotions Of Teaching Through Service‐Learning, Carrie W. Lecrom, Lynn Pelco, Jill W. Lassiter

Journal of Community Engagement and Higher Education

The authors used Coles’ (1993) framework of emotional satisfactions and hazards to examine the experiences of faculty members teaching service-learning classes for the first time. Seven faculty from two institutions completed monthly reflections and focus groups for one year. Qualitative analysis indicated that faculty experienced several of Coles’ emotional satisfactions and hazards, were prone to emotional contagion, and depended on colleague mentoring to navigate the experiences of using service-learning pedagogy for the first time.

Review Of The Interlinked Environmental, Economic, And Social Realms Of Sustainability, Tony Kealy

Books/Book chapters

Sustainable development (sustainability) objectives are achieved when environmental, economic, and social/human aspects are respectfully considered in organisational public and private decision-making. This study reviews and critiques these three main components as attempts are made to achieve sustainable business development. The results allow decision-makers to identify issues that need to be considered when making decisions regarding environmental, economic, and human resources. A literature review methodology is utilized. The findings highlighted flaws in all three main sustainability components. Renewable energy generators are benefiting the environmental component of sustainability, but at a slower pace than anticipated. Global indicators of environmental degradation are on …

High-Throughput Analysis Of Topographical Cues For The Expansion Of Murine Pluripotent Stem Cells, Abigail Anne Conner, Yuan Yao, Sarah W. Chan, Deepak Jain, Suzanne M. Wong, Evelyn K. Yim, Muhammad Rizwan

Michigan Tech Publications

The expansion of pluripotent stem cells (PSCs) in vitro remains a critical barrier to their use in tissue engineering and regenerative medicine. Biochemical methods for PSC expansion are known to produce heterogeneous cell populations with varying states of pluripotency and are cost-intensive, hindering their clinical translation. Engineering biomaterials to physically control PSC fate offers an alternative approach. Surface or substrate topography is a promising design parameter for engineering biomaterials. Topographical cues have been shown to elicit profound effects on stem cell differentiation and proliferation. Previous reports have shown isotropic substrate topographies to be promising in expanding PSCs. However, the optimal …

Finance Committee Meeting - Open Session Book (2) 08/22/2024, Uc Law Sf

2024 Board of Directors Agenda and Materials

No abstract provided.

In Memoriam: Albert Burky, Professor Emeritus Of Biology, Dave Larsen

College of Arts and Sciences Newsroom

Albert Burky, a biology professor who taught for nearly 50 years at UD, where he researched ecology and evolution, died Aug. 9.

Summer Fellow Reese Jones Analyzes Metal Contaminates In Old Books, Office Of University Communications

Gardner-Webb NewsCenter Archive

For her Summer Scholar Fellowship, Gardner-Webb University senior Reese Jones learned how to use the new X-Ray Fluorescent (XRF) Spectrometer in the Department of Natural Sciences. The instrument was purchased recently with a grant from the Cannon Foundation. Working with her mentor, Professor of Chemistry Dr. Venita Totten, Jones gained valuable experience for the next steps in her educational journey to become a pediatrician.

The Myth Of The Alpha Wolf, Prairie Kidd

Affirmation/Transformation: Fandom Created

Prairie Kidd
The Myth of the Alpha Wolf, 2024
Fandom: Omegaverse
Audio Essay
N/A
Collection of the creator

Rating: Mature
Tags: omegaverse, alpha male, beta male, omega, knotting, breeding, mlm, gay stuff, academic gay stuff, a/b/o

Creator's Notes: The understanding of human sexuality can often be understood through other animals. In the 70s, a researcher concluded that wolves work in packs, naming one as the Alpha, or top dog. The other wolves were given, thus, a classification under the Greek alphabet to represent their rank, and sexual status. This idea was so pronounced that it made its way into …

Epidemiologic Trends In Cutaneous Squamous Cell Carcinoma From 2011 To 2021 At All Africa Leprosy, Tuberculosis, And Rehabilitation Training Center (Alert) In Addis Ababa, Ethiopia, Tizita Yosef, Wondwossen Ergete, Rishab R Revankar, Heli A. Patel, Tsegaye Hailu Kumsa, Vishal A Patel, Selfu Girma, Benjamin K Stoff

SKMC Student Presentations and Publications

BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is the most common keratinocyte carcinoma in dark-skinned ethnic groups. Available studies are primarily focused on white populations, with fewer data available for black Africans, including Ethiopians. Therefore, less priority may be given to treatment and prevention in this population.

OBJECTIVE: To determine the prevalence and risk factors of cSCC among patients presenting to All Africa Leprosy, Tuberculosis, and Rehabilitation Training Center , Addis Ababa, Ethiopia.

METHODS: A literature review was performed to determine existing knowledge. A retrospective descriptive cross-sectional study was then conducted based on stored data of confirmed cases of cSCC from …

Factors That Predict Immune Function Resilience Among Adult Survivors Of Childhood Sexual Abuse, Samantha Dewey Colombo

Walden Dissertations and Doctoral Studies

Not long ago, researchers and providers learned about the negative impacts that adverse childhood experiences have on not only the psychological health of the survivor but also the physical. Adverse physical health outcomes such as cardiovascular disease, cancer, diabetes mellitus, autoimmune diseases, and more were identified as a risk for this population. These adverse outcomes occur largely due to immune dysfunction through systemic inflammation. One group within those who have adverse childhood experiences is those who have survived childhood sexual abuse. This group has experienced profound trauma that can impact them many years later psychologically, physically, and spiritually. Resilience factors …

Active Learning Pipeline To Identify Candidate Terms For A Cdss Ontology, Xia Jing, Rohan Goli, Keerthana Komatineni, Shailesh Alluri, Nina Hubig, Hua Min, Yang Gong, Dean F Sittig, Paul Biondich, David Robinson, Christian Nøhr, Arild Faxvaag, Adam Wright, Timothy Law, Lior Rennert, Ronald Gimbel

Faculty, Staff and Student Publications

Ontology is essential for achieving health information and information technology application interoperability in the biomedical fields and beyond. Traditionally, ontology construction is carried out manually by human domain experts (HDE). Here, we explore an active learning approach to automatically identify candidate terms from publications, with manual verification later as a part of a deep learning model training and learning process. We introduce the overall architecture of the active learning pipeline and present some preliminary results. This work is a critical and complementary component in addition to manually building the ontology, especially during the long-term maintenance stage.

Soft Sets Extensions: Innovating Healthcare Claims Analysis, Daniela Gifu, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In the dynamic arena of healthcare research, where the complexities of data often rival the intricacies of biological systems, the ability to model and analyze such multifaceted datasets is crucial. This comprehensive review delves into the evolution and application of Soft Sets and their extensions, including HyperSoft Sets, SuperHyperSoft Sets, IndetermSoft Sets, IndetermHyperSoft Sets, and TreeSoft Sets, in healthcare claims data analysis.

Sexannodb, A Knowledgebase Of Sex-Specific Regulations From Multi-Omics Data Of Human Cancers, Mengyuan Yang, Yuzhou Feng, Jiajia Liu, Hong Wang, Sijia Wu, Weiling Zhao, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

Background

Sexual differences across molecular levels profoundly impact cancer biology and outcomes. Patient gender significantly influences drug responses, with divergent reactions between men and women to the same drugs. Despite databases on sex differences in human tissues, understanding regulations of sex disparities in cancer is limited. These resources lack detailed mechanistic studies on sex-biased molecules.

Methods

In this study, we conducted a comprehensive examination of molecular distinctions and regulatory networks across 27 cancer types, delving into sex-biased effects. Our analyses encompassed sex-biased competitive endogenous RNA networks, regulatory networks involving sex-biased RNA binding protein-exon skipping events, sex-biased transcription factor-gene regulatory networks, …