Digital Commons Network^™

Interpretable Classification Of Myositis From Muscle Ultrasound Images, Bishwa Karki, Xin Zhong, Yu-Che Chen, Chun-Hua Tsai

Information Systems and Quantitative Analysis Faculty Publications

This study is dedicated to designing and advancing machine learning (ML) algorithms for classifying normal and abnormal muscular tissues, thereby aiding neurologists in diagnosing inclusion body myositis (IBM). Our work mainly aims to leverage machine learning and recent state-of-the-art (SOTA) algorithms to recognize and diagnose myositis from muscle ultrasound images in the preliminary stage and support the traditional diagnostic methodology. Initially, we used an open-source ultrasound image dataset to construct and refine initial models using VGG-16. We employed the Grad-CAM method to annotate muscle ultrasound images and delineate regions of interest (ROI). Subsequent experiments enhanced the VGG16 architecture through extensive …

Take Action To Implement Your Professional Learning, Amie Cieminski

CETL Blog

Amie Cieminski, associate professor and CETL advisory board member, wants to encourage all UNC faculty and staff to review the CETL learning opportunities and consider joining a learning community or attending a webinar. Then, she wants to challenge you to implement the new learning. Do you need some quick ideas to move from plans to action? In this previously published blog for The Teaching Professor, she highlights several ideas for moving to action: take a risk, get started, start small, learn in community, facilitate learning for others, or find a learning partner. These ideas come from her experiences with CETL …

Applying The 5ps Of Cultural Ecosystem Services For Urban Agricultural And Natural Resources Programming, Mayra I. Rodriguez Gonzalez

Journal of Extension

Beyond adapting extension programs for an urban audience, Urban Extension strives to reach an underserved audience that hugely overlaps with marginalized populations. This means that cultural competence is crucial for successful program implementation. The following article outlines the application of the 5P framework of Cultural Ecosystem Services as a tool for laying out the base to a culturally competent extension program. Although originally intended for urban planners, when applied widely for program development it allows accounting for place, past, people, practices, and purposes in a simple manner without overlooking importance context pertaining the target audience.

A Citizen Science Approach To Assess Management Of An Invasive Species, William Lester, Emily Kraus

Journal of Extension

Citizen science allows for broadening the scope of research by increasing data points and geographical scale. Here, Institute A and Institute B show that citizens utilized various outreach platforms to increase their knowledge of an invasive species the air potato vine, Dioscorea bulbifera, and its biological control agent the air potato beetle, Lilioceris cheni. Citizen scientists also contributed data on the distribution and establishment of the beetle, and reported on behavior change, and attitude toward the project. Valuable lessons were learned in designing surveys and training the citizens in order to increase the quality of their contributions.

Biology Department Publications: 2005, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2005. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2007, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2007. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2011, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2011. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2006, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2006. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2018, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2018. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2012, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2012. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2014, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2014. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2016, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2016. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2022, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2022. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2019, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2019. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2020, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2020. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2017, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2017. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Malat1 Mediates Tet2 Loss Of Function-Driven Oncogenic Inflammation Via Rna Shielding Of Nf- Kappa B P65, Nana Adjoa Ben-Crentsil

USF Tampa Graduate Theses and Dissertations

TET2 is a dioxygenase that regulates gene expression and hematopoiesis by oxidizing 5-methylcytosine residues on DNA to 5-hydroxymethylcytosine. TET2 mutations are common genetic events in hematological disorders. For example, TET2 is the most frequently mutated gene in Chronic Myelomonocytic Leukemia and occurs in about 33% of other myeloid malignancies. It is also the second commonest mutation in clonal hematopoiesis of indeterminate potential (CHIP), a common premalignant condition in the elderly. TET2 mutations arise in founding clones and are implicated in many non-hematological sequelae seen in CHIP like atherosclerotic disease, chronic liver disease, and severe microbial infections.

The development of TET2-deficient …

Biology Department Publications: 2023, Sam Lindgren

Biology Department Bibliographies

This document is a non-comprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2023. It indexes those publications available through PubMed and Scopus, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2015, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2015. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2010, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2010. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2009, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2009. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2013, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2013. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Biology Department Publications: 2008, Sam Lindgren

Biology Department Bibliographies

This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2008. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.

Synergistic Inhibition Of Hiv-1 Regulatory Function Using A Dual Expression Shrna Plasmid, Christine Sanderson, William H. Jackson

Journal of the South Carolina Academy of Science

HIV infection of CD4⁺ T Helper lymphocytes results in a gradual loss of immune competence, which ultimately leads to development of the acquired immune deficiency syndrome (AIDS). HIV-1 expresses two regulatory proteins, Tat and Rev, which act to upregulate viral transcription and facilitate mRNA transport enhancing the rate of translation. Inhibition of Tat and Rev have been shown to block virus replication. Therefore, Tat and Rev represent critical key points in the virus replication cycle. This study investigated the potential of RNA interference (RNAi) to inhibit these proteins using short hairpin RNAs (shRNAs). For this, plasmids expressing shRNAs targeting …

Cardiomyocyte-Derived Small Extracellular Vesicle: A New Mechanism Driving Diabetic Cardiac Fibrosis And Cardiomyopathy, Yu Li, Yunhui Du, Yang Liu, Xiuhuan Chen, Xinxin Li, Yanru Duan, Yanwen Qin, Huirong Liu, Xinliang Ma, Shaoping Nie, Huina Zhang

Department of Emergency Medicine Faculty Papers

Rationale: Diabetic cardiomyopathy is one of the major diabetic cardiovascular complications in which fibrosis plays a critical pathogenetic role. However, the precise mechanisms by which diabetes triggers cardiac fibrosis in the heart remain elusive. Small extracellular vesicles (sEVs) play an important role in the cellular communication. Nevertheless, whether and how diabetes may adversely alter sEVs-mediated cardiomyocyte-fibroblast communication, promoting diabetic cardiac fibrosis and contributing to diabetic cardiomyopathy, has not been previously investigated. Methods and results: High-fat diet (HFD)-induced and genetic (db/db) type 2 diabetic models were utilized. Cardiomyocyte sEVs (Myo-sEVs) were isolated by ultracentrifugation. Normal cardiomyocyte-derived Myo-sEVs attenuated diabetic cardiac fibrosis …

Peer Group Influence On The Antecedents Of Academic Coping Over The First Year Of Middle School, Daniel Lee Grimes

Dissertations and Theses

The motivational model of academic coping provides a framework for investigating the motivational antecedents and social contextual influences on ways of coping with academic adversity during the transition to middle school. Two studies were conducted to investigate the roles of three motivational antecedent variables of academic coping: perceived control, autonomous motivation, and catastrophizing. Study 1 investigated relationships between the motivational variables and academic coping across the first year of middle school. Study 2 investigated peer group influences on the motivational variables and on academic coping. Data from an entire cohort of 366 sixth students in the only middle school in …

Neighborhood Disadvantage, Parenting, And Dna Methylation During Childhood, Malcolm Barker-Kamps

All ETDs from UAB

Being raised in a disadvantaged neighborhood increases the risk of adult obesity, chronic inflammation, and epigenetic aging even when adjusting for family socioeconomic status (SES). Because little is understood regarding the timing of these outcomes through development and possible moderating effects of the family environment, this project investigated the relationship between neighborhood disadvantage and DNA methylation in children and whether this association varies across child age, parenting behaviors, or neighborhood cohesion. The study included 112 parents (Mage=27.5; SD=1.06) and 160 children, ages 0-14 (Mage =3.89, SD=3.29; 54% female; 90% African American; 10% White), from the Birmingham Youth Violence Study. Neighborhood …

Beyond Chronic Fatigue: Studying The Role Of Neuroinflammation, Glutamate, And Glutamine, Indonesia Alohn Jordan

All ETDs from UAB

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, multifaceted disease characterized by persistent, severe fatigue lasting six months or longer that is not relieved by rest. An estimated 20 million people worldwide suffer from ME/CFS. ME/CFS has long been suspected to be a post-viral illness, as viral infections can stimulate inflammatory cytokine production. Millions of coronavirus disease 2019 (COVID-19) patients are also predicted to develop persistent symptoms that mimic ME/CFS symptomology after the resolution of the acute infection, referred to as Post-Acute Sequelae of COVID-19 (PASC). Inflammatory mediators produced by sustained microglia activation have been shown to lead to illness …

Investigating The Role Of The Static And Hyperviscous Mucus Defect On The Development Of Bacterial Infection In The Cystic Fibrosis Rat, Mikayla Murphree-Terry

All ETDs from UAB

INVESTIGATING THE ROLE OF THE STATIC AND HYPERVISCOUS MUCUS DEFECT ON THE DEVELOPMENT OF BACTERIAL INFECTION IN THE CYSTIC FIBROSIS RAT MIKAYLA MURPHREE-TERRY GRADUATE BIOMEDICAL SCIENCES - MICROBIOLOGY ABSTRACT Cystic fibrosis (CF) is a genetic disease caused by mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, resulting in dysfunctional CFTR. In the lungs, CFTR dysfunction results in dehydrated mucus that is adherent to epithelia. In the gut, thick mucus can mix with feces to form an obstruction, known as distal intestinal obstruction syndrome (DIOS). Additionally, CF mucus has a higher percentage of solids. The main solid component of …

Ai Case Study Assignment, Jeffrey Anvari-Clark

AI Assignment Library

This assignment is intended to students develop digital literacy and social work skills by creating a social work case note using ChatGPT, Claude, or a similar AI software. By using the software, creating the note, and reflecting on the process, students will learn to: 1. appropriately integrate advanced AI technology into their work as helping professionals, 2. analyze the benefits and limits of AI usage (along with ethical considerations), 3. create a case note that is clear, concise, and comprehensive, and 4. evaluate the role of social demographics on individual well-being. The assignment is for a 200-level course, a prerequisite …