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Ioc Consensus Statement: Interpersonal Violence And Safeguarding In Sport, Yetsa A. Tuakli-Wosornu, Kirsty Burrows, Kari Fasting, Mike Hartill, Ken Hodge, Keith Kaufman, Emma Kavanagh, Sandra L. Kirby, Jelena G. Macleod, Margo Mountjoy, Sylvie Parent, Minhyeok Tak, Tine Vertommen, Daniel J. A. Rhind Nov 2024

Ioc Consensus Statement: Interpersonal Violence And Safeguarding In Sport, Yetsa A. Tuakli-Wosornu, Kirsty Burrows, Kari Fasting, Mike Hartill, Ken Hodge, Keith Kaufman, Emma Kavanagh, Sandra L. Kirby, Jelena G. Macleod, Margo Mountjoy, Sylvie Parent, Minhyeok Tak, Tine Vertommen, Daniel J. A. Rhind

Psychology Faculty Publications and Presentations

Interpersonal violence (IV) in sport is challenging to define, prevent and remedy due to its subjectivity and complexity. The 2024 International Olympic Committee Consensus on Interpersonal Violence and Safeguarding aimed to synthesise evidence on IV and safeguarding in sport, introduce a new conceptual model of IV in sport and offer more accessible safeguarding guidance to all within the sports ecosystem by merging evidence with insights from Olympic athletes.


“It’S Essential We Learn How To Grow For Ourselves”: The Legacies Of Black Gardening In Racialized Food Systems., Funmi Odumosu Nov 2024

“It’S Essential We Learn How To Grow For Ourselves”: The Legacies Of Black Gardening In Racialized Food Systems., Funmi Odumosu

USF Tampa Graduate Theses and Dissertations

In this thesis, I aim to investigate the impact of food racism on Black communities, with a specific focus on the importance of gardening in combatting food apartheid and fostering holistic connections to nature and community in school-aged children. Inequitable access to major retail supermarkets and unequal distribution of healthy food options are intentionally occurring patterns in the food spaces of predominately Black communities. These food system inequities exacerbate a lack of consumption and potential consequences on the health and well-being of children of color particularly during critical physical and cognitive developmental periods.

Many solutions to these inequities entail implementing …


Assessing Fish Species Richness Using Edna And Seine Nets In A Restored Estuary In Tampa Bay, Florida, Us, Alex Seigel Nov 2024

Assessing Fish Species Richness Using Edna And Seine Nets In A Restored Estuary In Tampa Bay, Florida, Us, Alex Seigel

USF Tampa Graduate Theses and Dissertations

Coastal estuarine systems associated with the Tampa Bay region along the Gulf of Mexico, Florida, US, are critical to the region’s fishing industry, which contributes significantly to Florida’s economy. Restoring estuaries along the Gulf Coast of Florida is an investment in Florida’s environmental health and economic stability. Estuaries serve as nurseries for many marine species, including commercially important organisms like finfish. Restoring these areas can enhance fish stocks and, by extension, boost the economic returns from commercial and recreational fishing. In this study, differences in fish species richness were compared among a seven-month period in 2022, seine nets (once in …


Ecological Epidemiology Of The Fungal Pathogen Ophidiomyces Ophiodiicola In Southeastern U.S. Snake Populations: Distribution, Drivers, And Anthropogenic Risk Factors, Shivam Shukla Nov 2024

Ecological Epidemiology Of The Fungal Pathogen Ophidiomyces Ophiodiicola In Southeastern U.S. Snake Populations: Distribution, Drivers, And Anthropogenic Risk Factors, Shivam Shukla

USF Tampa Graduate Theses and Dissertations

Studying wildlife diseases is an important conservation measure, as many pathogens are a critical threat to biodiversity worldwide. Ophidiomycosis is an emerging infectious disease caused by the invasive fungal pathogen Ophidiomyces ophiodiicola that affects a wide variety of snake species, often causing mortality. There has been limited surveillance for ophidiomycosis in the southeastern United States’ (US) snake populations and research into the effects of anthropogenic disturbance on disease spread is also lacking. Thus, this project aimed to quantify the distribution and drivers (taxonomic, anthropogenic, and morphological) of ophidiomycosis in Florida, Louisiana, and Mississippi’s free ranging snakes as well as study …


Species Distribution Modeling With Environmental Time Series Data And Deep Learning, Austin M. Smith Nov 2024

Species Distribution Modeling With Environmental Time Series Data And Deep Learning, Austin M. Smith

USF Tampa Graduate Theses and Dissertations

Species distribution models (SDM) are frequently used to gain ecological understanding and guide conservation decisions. These models are developed with a wide variety of procedures - from regression-based approaches to more modern machine learning algorithms - but a requirement almost all share is the use of predictor variables that strongly simplify the temporal variability of driving factors. These static features are chosen by the user, which can incorporate unnecessary bias into a study. Additionally, current data preparation techniques often remove variables from the process entirely, which inherently removes information that may still be of importance. Conversely, novel architectures of deep …


A Circular Engineered Sortase For Interrogating Histone H3 In Chromatin, Samuel D Whedon, Emily Zahn, Benjamin A Garcia, Et Al. Nov 2024

A Circular Engineered Sortase For Interrogating Histone H3 In Chromatin, Samuel D Whedon, Emily Zahn, Benjamin A Garcia, Et Al.

2020-Current year OA Pubs

Reversible modification of the histone H3 N-terminal tail is critical in regulating chromatin structure, gene expression, and cell states, while its dysregulation contributes to disease pathogenesis. Understanding the crosstalk between H3 tail modifications in nucleosomes constitutes a central challenge in epigenetics. Here we describe an engineered sortase transpeptidase, cW11, that displays highly favorable properties for introducing scarless H3 tails onto nucleosomes. This approach significantly accelerates the production of both symmetrically and asymmetrically modified nucleosomes. We demonstrate the utility of asymmetrically modified nucleosomes produced in this way in dissecting the impact of multiple modifications on eraser enzyme processing and molecular recognition …


Study On The Seasonal Endobacterial Profile Of Avicennia Officinalis, Focusing On Core Bacterial Consortia Within Mangrove Pneumatophores, Devi R R, Vinod Prabhakar Nov 2024

Study On The Seasonal Endobacterial Profile Of Avicennia Officinalis, Focusing On Core Bacterial Consortia Within Mangrove Pneumatophores, Devi R R, Vinod Prabhakar

Karbala International Journal of Modern Science

Microhabitats are smaller pockets of ecosystems with unique conditions and they serve as major contributors of species richness. Mangrove plants offer a diverse array of such microhabitats (rhizosphere, phyllosphere, endosphereetc), and the inhabitant bacteria benefit the host by providing better salinity tolerance, faster and better nutrient mobilization, protection from phytopathogens and assistance in seed germination. Identification of such beneficial bacteria,their growth requirementsandmetabolism, willhave direct application in the field of agriculture and ecosystem restoration. Hence in this study, effort has been made to elucidate the seasonal numerical and compositional profile of pneumatophore bacterial consortia of Avicennia officinalis, from the mangrove …


Rethinking Human-Autonomy Teamwork In The Context Of Design And Robotic Fabrication, Iremnur Tokac Celikyay, Caja Thimm, Sigrid Brell-Cokcan Nov 2024

Rethinking Human-Autonomy Teamwork In The Context Of Design And Robotic Fabrication, Iremnur Tokac Celikyay, Caja Thimm, Sigrid Brell-Cokcan

Human-Machine Communication

The integration of autonomous agents in design is challenging due to its unstructured nature. The increasing focus on human-robot interaction (HRI) is driven by its potential to address this issue, enabling human-robot teams to effectively manage creative design tasks. This paper aims to identify interactive processes among the agencies of humans, robots, and materials. We explore how HRI can shift robotic fabrication from a linear deterministic process to an iterative co-creation one. Through reflective analysis of robotic fabrication studies, we illustrated how interaction interfaces can distribute agency among humans, robots, and materials while negotiating the design intent with material and …


Silent Drift, Nikolas Cox Nov 2024

Silent Drift, Nikolas Cox

Night Flight: Online Literary Journal

No abstract provided.


It's So Meta: Cjrt On Jrrt On Jrrt In Cjrt Within The 'Athrabeth Finrod Ah Andreth', Kristine Larsen Nov 2024

It's So Meta: Cjrt On Jrrt On Jrrt In Cjrt Within The 'Athrabeth Finrod Ah Andreth', Kristine Larsen

Journal of Tolkien Research

The nested doll structure of the various notes, commentary, drafts, and ancillary texts published alongside the main text of the "Athrabeth Finrod ah Andreth" demonstrate both the depth (and challenges) of Christopher Tolkien's 'History of Middle-earth' collection, especially as they connect with the "Tale of Adanel."


Giorgio Agamben's Analysis Of The Mechanism Of Exclusion Or The Logic Of Sovereign Power, Georges De Schrijver Nov 2024

Giorgio Agamben's Analysis Of The Mechanism Of Exclusion Or The Logic Of Sovereign Power, Georges De Schrijver

Budhi: A Journal of Ideas and Culture

In Homo sacer: Sovereign Power and Bare Life, Giorgio Agamben extends Michel Foucault’s notion of biopolitics to include life, stripped bare, that is placed completely at the mercy of the powers that be. For him, the biopolitical paradigm is no longer the asylum but the concentration camp. Agamben drew the inspiration for this shift from Walter Benjamin, who decades ago had observed that the state of exception favored by the Nazi jurist Carl Schmitt had become the rule. Certain strata of the population, in this case the Jewish citizens in Germany, were abandoned by the law while continuing to fall …


Philosophy And Transformative Learning: Lessons In Natural Resource Management From Cordillera Communities, Julius D. Mendoza Nov 2024

Philosophy And Transformative Learning: Lessons In Natural Resource Management From Cordillera Communities, Julius D. Mendoza

Budhi: A Journal of Ideas and Culture

In this paper, the objects of philosophical reflection are the important lessons learned from a participatory action research program conducted by the Cordillera Studies Center of UP Baguio in Sagada, Mountain Province, in Northern Luzon, Philippines, which ran from March 1997 to February 2001. This research program used the Community Based Natural Resource Management (CBNRM) approach. Concepts of philosophy are made to re-describe “second order” concepts of theory, as well as “first order” concepts of community-based natural resource management research, planning, testing, implementation, and monitoring. Concepts used in the context of field work are given philosophical re-descriptions in the form …


Conformational Flexibility Of The C-Terminal Region Influences Distal Active Site Residues Across The Tautomerase Superfamily, Christopher Argueta, Andrew Parkins, Georgios Pantouris Nov 2024

Conformational Flexibility Of The C-Terminal Region Influences Distal Active Site Residues Across The Tautomerase Superfamily, Christopher Argueta, Andrew Parkins, Georgios Pantouris

Pacific Faculty Work

Consisting of more than 11,000 members distributed over five families, the tautomerase superfamily (TSF) is a large collection of proteins with diverse biological functions. While much attention has been given to individual TSF enzymes, a majority remain structurally and functionally uncharacterized. Given its large size, studying a representative member of each family offers a viable approach for extracting mechanistic insights applicable to the entire superfamily. In this study, cis-3-chloroacrylic acid dehalogenase (cis-CaaD), 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI), malonate semialdehyde decarboxylase (MSAD), and 4-oxalocrotonate tautomerase (4-OT) were referenced against the well-studied macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) using triplicate 1 …


Conquer And Prevail Issue 176 November 21 2024, Wofford College. Office Of Marketing And Communications Nov 2024

Conquer And Prevail Issue 176 November 21 2024, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.


Micro And Nano Plastics: Contaminants In Beverages And Prevention Strategies, Chang Ma, Karna Ramachandraiah, Guihun Jiang Nov 2024

Micro And Nano Plastics: Contaminants In Beverages And Prevention Strategies, Chang Ma, Karna Ramachandraiah, Guihun Jiang

School of Public Health Faculty Publications

The widespread use of plastics in beverage packaging has led to the accumulation of microplastics (MPs) and nanoplastics (NPs) in beverages, which poses significant environmental and health hazards. This review explores the sources, entry pathways, and risk factors for MPs and NPs in beverages, emphasizing their toxicological profiles and harmful effects on human health and the environment. Methods for detecting MPs and NPs in beverages are discussed, highlighting the need for standardized testing protocols. Furthermore, future solution strategies, challenges, and preventive measures for mitigating MP and NP contamination in beverages are proposed, including advanced filtration systems, the development of alternative …


Queering The Relationship Between Research, Researcher And Research Participant: Procedural Ethics, Relational Ethics, And Inverted Hierarchies, Val Meneau Nov 2024

Queering The Relationship Between Research, Researcher And Research Participant: Procedural Ethics, Relational Ethics, And Inverted Hierarchies, Val Meneau

The Qualitative Report

Ethics committees (ECs) typically base their decisions on established assumptions about the impact of the research process, the researcher and the participant on each other, which my doctoral research project failed to meet. This paper discusses the challenging clash between my experiences as a queer scholar doing fieldwork and the expectations of my EC. I argue that queer feminist ethnography complicates the established assumptions concerning the impact of the research process, researcher, and participant on each other. In doing so, I argue that we need models of this relationship that allow us to capture its complexity, for example in the …


Population Increases Of The Threatened American Burying Beetle (Nicrophorus Americanus) Linked To Large-Scale Collaborations In A Working Lands Ecoregion, Caleb P. Roberts, Alison K. Ludwig, Dillon T. Fogarty, Erica F. Stuber, Daniel R. Uden, Thomas L. Walker Jr, Dirac Twidwell Nov 2024

Population Increases Of The Threatened American Burying Beetle (Nicrophorus Americanus) Linked To Large-Scale Collaborations In A Working Lands Ecoregion, Caleb P. Roberts, Alison K. Ludwig, Dillon T. Fogarty, Erica F. Stuber, Daniel R. Uden, Thomas L. Walker Jr, Dirac Twidwell

Wildland Resources Faculty Publications

Woody plant encroachment and row-crop agricultural land conversion are existential threats to species that rely on grassland ecosystems. The American Burying Beetle (Nicrophorus americanus) is a threatened species whose largest remnant populations are predominantly located in grassland ecoregions comprised of privately-owned ranching lands. Here, we seek to determine functional scaling patterns and population trends of the American Burying Beetle in the face of conservation threats and grassland restoration. We used 13 years (2007–2019) of American Burying Beetle abundance data collected from permanent sampling locations across the Loess Canyons ecoregion (Nebraska, USA), where a network of ranchers have been …


Γ -Aapeptides Targeting Amyloid-Β Pathway And Neural Repair For Alzheimer’S Disease Treatment, Ning Shen Nov 2024

Γ -Aapeptides Targeting Amyloid-Β Pathway And Neural Repair For Alzheimer’S Disease Treatment, Ning Shen

USF Tampa Graduate Theses and Dissertations

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques and progressive neuronal degeneration. Despite extensive research, no treatments have been able to effectively halt or reverse the progression of the disease. This study aimed to evaluate the therapeutic potential of two novel γ-AApeptides, HW-C9 and 125-6b, in AD treatment, assessing both their individual and combined effects. HW-C9 was designed to inhibit Aβ aggregation, while 125-6b was developed to promote neuronal growth and repair. Initially, the therapeutic effects of HW-C9 and 125-6b were assessed both in vitro and in vivo. The results showed that HW-C9 …


Acoustic Energy For Use In Mass Spectrometry, Ashton N. Taylor Nov 2024

Acoustic Energy For Use In Mass Spectrometry, Ashton N. Taylor

USF Tampa Graduate Theses and Dissertations

Analyzing lipid assemblies, including synthetically produced liposomes and naturally produced extracellular vesicles (EVs), is challenging due to their size, diverse composition, and tendency to aggregate. EVs contain a complex variety of lipids, proteins, and other metabolites. EVs composition can provide us insight into what is happening inside the body and a subcellular level and have potential for noninvasive biomarkers. Liposomes are vesicles that form with a simple phospholipid bilayer membrane and play important roles in drug delivery systems. The use of mass spectrometry (MS) allows for broad analysis of lipids from different classes but their release from the higher order …


Safeguarding Ecological Knowledge From The Effects Of Climate Change: An Archival Approach, Daena Jean Carrillo Nov 2024

Safeguarding Ecological Knowledge From The Effects Of Climate Change: An Archival Approach, Daena Jean Carrillo

LSU Doctoral Dissertations

Creating resources that facilitate the preservation of community-based archives and ecological knowledge in the Louisiana coastal region is integral to its survival amongst the effects of climate change. Research and records created and stored within the Louisiana coastal region have a higher predisposition to the drastic and pervasive effects of climate change and natural disasters. Modern archivists can insert themselves into the work of climate change action through their advocacy of safeguarding collections that have been created by communities and individuals through raw scientific and observational data and unpublished research. Just as archivists continue to frame their professional work around …


Characterizing West Florida Shelf Reef Fish Communities Using A Scientific Echosounder, Edmund A. Hughes Nov 2024

Characterizing West Florida Shelf Reef Fish Communities Using A Scientific Echosounder, Edmund A. Hughes

USF Tampa Graduate Theses and Dissertations

The advancement and application of non-invasive fisheries survey technologies, such as the scientific echosounder, have significantly enhanced our understanding of fish populations and their habitats, more recently in regions where traditional sampling methods are limited, such as complex reef habitats. This research, conducted as part of the Continental Shelf Characterization, Assessment, and Mapping Project (C-SCAMP) on the West Florida Shelf, leverages acoustic and visual technologies to investigate the distribution of fish densities, fish target strength and length relationships, and the relationship between seafloor topography and fish biomass distribution.

The first study compared reef fish densities estimated from near-concurrent acoustic (Simrad …


Why Is Fish Welfare Still So Neglected?, Caroline M. Maia Nov 2024

Why Is Fish Welfare Still So Neglected?, Caroline M. Maia

Animal Sentience

Oldfield & Bonano (O&B) address an important problem in the field of fish welfare, one that calls for greater attention from scientists and practitioners. O&B show that fish welfare, particularly at the psychological level, is under-investigated. They focus mainly on zoos and aquaria, but their concerns extend also to other domains, including fish farming. Fish are sentient animals; priority should be given to their welfare in all environments where they are under human care.


Isolation And Characterization Of Lignin From Oil Palm Shells Using A Precipitation Method With Sulfuric Acid And Polyaluminum Chloride As Coagulant, Eny Kusrini, Ria Yolanda Arundina, Anwar Usman, Resti Marlina, Bambang Subiyanto, Volkan Degirmenci, Nofrijon Sofyan, Yudan Whulanza Nov 2024

Isolation And Characterization Of Lignin From Oil Palm Shells Using A Precipitation Method With Sulfuric Acid And Polyaluminum Chloride As Coagulant, Eny Kusrini, Ria Yolanda Arundina, Anwar Usman, Resti Marlina, Bambang Subiyanto, Volkan Degirmenci, Nofrijon Sofyan, Yudan Whulanza

AUIQ Complementary Biological System

Lignin has useful and significant properties such as stiffness, resistance to UV radiation, antioxidant, antimicrobial, high thermal stability, and high carbon content. Due to these properties, lignin can be used for several applications including wood adhesive, carbon-based material, and can be developed as a functional material composite. Isolation and utilization of lignin from lignocellulosic biomass offers significant opportunities in various now and future industrial applications mainly for development advanced materials. In this study, isolation and characterization of lignin from oil palm shells (OPS) was conducted. Lignin was isolated from OPS using the precipitation method with sulfuric acid and coagulation using …


Pedagogy: Teaching Practices Of American Colonial Educators In The Philippines, Isabel Pefianco Martin Nov 2024

Pedagogy: Teaching Practices Of American Colonial Educators In The Philippines, Isabel Pefianco Martin

Kritika Kultura

Filipino historian and essayist Renato Constantino wrote: “With American education, the Filipinos were not only learning a new language; they were not only forgetting their own language; they were starting to become a new type of American.” What specific strategies did the American colonizers use to create this new type of American? How did they use the public schools to produce their cultural clones? The answer may be found in the language and literature teaching practices of American colonial educators in the Philippines. This paper argues that the Anglo American canon of literature imposed on the Filipinos would not have …


Best Practice Toolkit For Increasing Colorectal Cancer Screenings In At-Risk Adults, Zoe Windfelder Nov 2024

Best Practice Toolkit For Increasing Colorectal Cancer Screenings In At-Risk Adults, Zoe Windfelder

Student Scholarly Projects

Adult individuals at risk for colorectal cancer (CRC) do not have a direct, accessible best-practice toolkit to follow for screening measures. Research showed that at least three guidelines (i.e., American Cancer Society [ACS], American College of Gastroenterology [ACG], and U.S. Preventive Services Task Forces [USPSTF]) are used interchangeably daily by interprofessional staff for individuals with average to high-risk variables. The project was guided by the following PICOT question: For interprofessional staff supporting the at-risk adult population for colorectal cancer (P), how does the development of a best practice for coordination of care toolkit (I) compared to no structured program strategy …


Cabotegravir Maintains Protective Efficacy In The Setting Of Bacterial Stis: A Secondary Analysis Of Hptn 083, Meredith E. Clement, Brett Hanscom, Daniel Haines, Jose A. Bazan, Nuntisa Chotirosniramit, Ryan Kofron, Sharon Mannheimer, Kenneth H. Mayer, Mayara Secco Torres Silva, Lydia Soto-Torres, Alex R. Rinehart, James F. Rooney, A Jennings, K Gomez-Feliciano, Marybeth Mccauley, Beatriz Grinsztejn, Raphael J. Landovitz, Et Al. Nov 2024

Cabotegravir Maintains Protective Efficacy In The Setting Of Bacterial Stis: A Secondary Analysis Of Hptn 083, Meredith E. Clement, Brett Hanscom, Daniel Haines, Jose A. Bazan, Nuntisa Chotirosniramit, Ryan Kofron, Sharon Mannheimer, Kenneth H. Mayer, Mayara Secco Torres Silva, Lydia Soto-Torres, Alex R. Rinehart, James F. Rooney, A Jennings, K Gomez-Feliciano, Marybeth Mccauley, Beatriz Grinsztejn, Raphael J. Landovitz, Et Al.

School of Medicine Faculty Publications

BACKGROUND: Sexually transmitted infections (STIs) have been shown to facilitate HIV transmission and acquisition. HPTN 083, a global clinical trial, demonstrated superiority of long-acting cabotegravir (CAB-LA) versus daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for HIV prevention among transgender women and cisgender men who have sex with men. This analysis assessed whether CAB-LA maintained protective efficacy when bacterial STIs (syphilis, rectal/urethral gonorrhea and chlamydia) were present. METHODS: STI events per 100 person-years (PY) were calculated, including by subgroups (age, race/ethnicity, gender, education, treatment arm, drug use, alcohol use, region/country, condom usage, partner number, marital status, baseline STI). Association between baseline factors …


Evaluating How Malaria Transmission Season, Residency, And Travel History Modify The Association Between Vector Control Method Use And P. Falciparum Infection In Accra, Ghana., Anna Beltrame Nov 2024

Evaluating How Malaria Transmission Season, Residency, And Travel History Modify The Association Between Vector Control Method Use And P. Falciparum Infection In Accra, Ghana., Anna Beltrame

USF Tampa Graduate Theses and Dissertations

Background. Urbanization and population movements increase urban malaria risk, necessitating adjustments to traditional control strategies. Data on vector control methods in urban African settings and their association with malaria risk remain limited.

Objectives. To evaluate the association between vector control methods and Plasmodium falciparum infection in Accra, Ghana, and how this association varies by malaria transmission season, residency, and travel history.

Methods. This observation study utilized data from two cross-sectional household surveys conducted in March-April and June-July 2024 as part of the MUSE study. Participants were household members over six months old who gave consent, randomly selected from 13 health …


A Retrospective Analysis Of Thrombosis And Covid-19 Mortality In Rural Midwestern Population, John Dunton, Kaitlin Bierman-Macke, Taylor Little, Nicholas Zuk, Nova Beyersdorfer, Scott Goade, Kerry Johnson, Greg Stahl, Robert Arnce Nov 2024

A Retrospective Analysis Of Thrombosis And Covid-19 Mortality In Rural Midwestern Population, John Dunton, Kaitlin Bierman-Macke, Taylor Little, Nicholas Zuk, Nova Beyersdorfer, Scott Goade, Kerry Johnson, Greg Stahl, Robert Arnce

Student Publications

Background

COVID-19 disease has caused a major global impact on health and mortality. This infection may predispose patients to thrombotic disease, caused by excessive inflammation, endothelial dysfunction, platelet activation, and stasis. In this study, we compared mortality rates in patients admitted to the hospital with the diagnosis of COVID-19, who also had the additional diagnosis of thrombosis with those who did not have thrombosis as an additional diagnosis.

Methods

This retrospective observational study compared mortality rates in patients admitted to the hospital with the diagnosis of COVID-19, with and without thrombosis, as well as those patients admitted to the hospital …


Evaluating The Safety Of Immune Checkpoint Inhibitors And Combination Therapies In The Management Of Brain Metastases: A Comprehensive Review, Vivek Mishra, Tulika Ranjan, Arun Maharaj, Manmeet Ahluwalia Nov 2024

Evaluating The Safety Of Immune Checkpoint Inhibitors And Combination Therapies In The Management Of Brain Metastases: A Comprehensive Review, Vivek Mishra, Tulika Ranjan, Arun Maharaj, Manmeet Ahluwalia

All Publications

No abstract provided.


Space: An Open-Source, Single-Cell Analysis Of Cell Painting Data, Fabio Stossi, Pankaj K Singh, Michela Marini, Kazem Safari, Adam T Szafran, Alejandra Rivera Tostado, Christopher D Candler, Maureen G Mancini, Elina A Mosa, Michael J Bolt, Demetrio Labate, Michael A Mancini Nov 2024

Space: An Open-Source, Single-Cell Analysis Of Cell Painting Data, Fabio Stossi, Pankaj K Singh, Michela Marini, Kazem Safari, Adam T Szafran, Alejandra Rivera Tostado, Christopher D Candler, Maureen G Mancini, Elina A Mosa, Michael J Bolt, Demetrio Labate, Michael A Mancini

Faculty, Staff and Students Publications

Phenotypic profiling by high throughput microscopy, including Cell Painting, has become a leading tool for screening large sets of perturbations in cellular models. To efficiently analyze this big data, available open-source software requires computational resources usually not available to most laboratories. In addition, the cell-to-cell variation of responses within a population, while collected and analyzed, is usually averaged and unused. We introduce SPACe (Swift Phenotypic Analysis of Cells), an open-source platform for analysis of single-cell image-based morphological profiles produced by Cell Painting. We highlight several advantages of SPACe, including processing speed, accuracy in mechanism of action recognition, reproducibility across biological …