Digital Commons Network^™

Eleven Quick Tips For Properly Handling Tabular Data, Marla Hertz, Ashley Mcneill

Libraries Professional Work

Proper handling of tabular data, i.e., spreadsheets, is an essential skill for most researchers. Well-curated tabular data has built-in quality control, is machine readable by downstream analysis applications, and ultimately saves researchers’ time. The increased expectation of data sharing grounded by funder and publisher policies has made it even more crucial to format and describe tabular data properly to ensure that it is FAIR—findable, accessible, interoperable, and reusable [1]. However, many researchers are not formally trained in the data management skills necessary to build strong tabular datasets. They may also struggle to anticipate the future needs and potential applications of …

A B-Polynomial Approach To Approximate Solutions Of Pdes With Multiple Initial Conditions, Muhammad I. Bhatti, Md. Habibur Rahman

Physics & Astronomy Faculty Publications

In this article, we present a novel B-Polynomial Approach for approximating solutions to partial differential equations (PDEs), addressing the multiple initial conditions. Our method stands out by utilizing two-dimensional Bernstein polynomials (B-polynomials) in conjunction with their operational matrices to effectively manage the complexity associated with PDEs. This approach not only enhances the accuracy of solutions but also provides a structured framework for tackling various boundary conditions. The PDE is transformed into a system of algebraic equations, which are then solved to approximate the PDE solution. The process is divided into two main steps: First, the PDE is integrated to incorporate …

2024-11-27 Celebrating Seattle’S Salmon Run With Bert The Salmon!, Madden Armstrong

The Spectator Online

No abstract provided.

Discordance Between Balance Ability And Perception Is Associated With Falls In Parkinson’S Disease: A Coordinated Analysis, Jason K. Longhurst, Andrew Hooyman, Merrill R. Landers, Martina Mancini, Erika Franzén, Breiffni Leavy, Hanna Johansson, Daniel Peterson

Physical Therapy Faculty Articles and Research

Background: The congruence or discordance between actual and perceived balance ability has been proposed to be linked to functional outcomes such as falls. However, gaps remain in our ability to quantify discordance, and its relationship to relevant outcomes.

Objective: To investigate a novel quantification of concordance/discordance between balance performance and perception and determine the relationship to falls among people with Parkinson’s disease (PwPD).

Methods: Data from 244 PwPD were aggregated from 5 previously conducted studies. Variables extracted included age, sex, Activities-Specific Balance Confidence scale (ABC; perceived balance), Timed Up and Go (TUG; balance performance), Movement Disorder Society Unified Parkinson Disease …

Association Mapping For Water Use Efficiency In Soybean Identifies Previously Reported And Novel Loci And Permits Genomic Prediction, Siva K. Chamarthi, Larry C. Purcell, Felix B. Fritschi, Jeffrey D. Ray, James R. Smith, Avjinder S. Kaler, C. Andy King, Jason D. Gillman

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Soybean is a major legume crop cultivated globally due to the high quality and quantity of its seed protein and oil. However, drought stress is the most significant factor that decreases soybean yield, and more than 90% of US soybean acreage is dependent on rainfall. Water use efficiency (WUE) is positively correlated with the carbon isotopic ratio ¹³C/¹²C (C13 ratio) and selecting soybean varieties for high C13 ratio may enhance WUE and help improve tolerance to drought. Our study objective was to identify genetic loci associated with C13 ratio using a diverse set of 205 soybean maturity …

The Brain Initiative Data-Sharing Ecosystem: Characteristics, Challenges, Benefits, And Opportunities, Sudhanvan Iyer, Kathryn Maxson Jones, Jill O Robinson, Nicole R Provenza, Dominique Duncan, Gabriel Lázaro-Muñoz, Amy L Mcguire, Sameer A Sheth, Mary A Majumder

Faculty, Staff and Students Publications

In this paper, we provide an overview and analysis of the BRAIN Initiative data-sharing ecosystem. First, we compare and contrast the characteristics of the seven BRAIN Initiative data archives germane to data sharing and reuse, namely data submission and access procedures and aspects of interoperability. Second, we discuss challenges, benefits, and future opportunities, focusing on issues largely specific to sharing human data and drawing on N = 34 interviews with diverse stakeholders. The BRAIN Initiative-funded archive ecosystem faces interoperability and data stewardship challenges, such as achieving and maintaining interoperability of data and archives and harmonizing research participants’ informed consents for …

Pediatric Renal Cell Carcinoma (Prcc) Subpopulation Environmental Differentials In Survival Disadvantage Of Black/African American Children In The United States: Large-Cohort Evidence, Laurens Holmes, Phatismo Masire, Arieanna Eaton, Robert Mason, Mackenzie Holmes, Justin William, Maura Poleon, Michael Enwere

College of Population Health Faculty Papers

OBJECTIVE: Renal cell carcinoma (RCC) is a rare but severe and aggressive pediatric malignancy. While incidence is uncommon, survival is relatively low with respect to acute lymphocytic leukemia (ALL), AML, lymphoma, ependymoma, glioblastoma, and Wilms Tumor. The pediatric renal cell carcinoma (pRCC) incidence, cumulative incidence (period prevalence), and mortality vary by health disparities' indicators, namely sex, race, ethnicity, age at tumor diagnosis, and social determinants of health (SDHs) as well as Epigenomic Determinants of Health (EDHs). However, studies are unavailable on some pRCC risk determinants, such as area of residence and socio-economic status (SES). The current study aimed at assessing …

Reflections On Intolerance In A Modern, Shrinking, And Pluralistic World, Roger Haight

Budhi: A Journal of Ideas and Culture

Reflections on Intolerance in a Modern, Shrinking, and Pluralistic World

Who Counts As Filipino? Philosophical Issues Of Identity And The Chinese Filipino, Noelle Leslie Dela Cruz

Budhi: A Journal of Ideas and Culture

This article examines some recent philosophical attempts to make sense of “identity” in light of the intersecting categories of race, ethnicity, and culture. It addresses a perennial issue brought up recently with regard to Filipino Chinese: Who counts as “Filipino?” Behind this question are assumptions that I scrutinize philosophically: that there is a “Filipino” and it is possible to identify who counts as such and who does not. I begin with a survey of existing paradigms of identity which I then apply to a critical analysis of recent public discourse spawned by anti-Chinese statements made by a prominent Filipino novelist. …

Ai-Assisted Faculty, Dean A. Goon

AI Summit

Consider the abbreviated faculty and student prompts below to get started. To design even better prompts, use the RICCE, which is more extended and iterative to expand the use of Generative AI for teaching and learning.

Adult Learning And Teacher Inquiry: A Natural Match?, Stephen P. Gordon Dr., Jovita M. Ross-Gordon Dr.

i.e.: inquiry in education

This paper considers the potential benefits of integrating the knowledge base on adult learning with teacher inquiry. The first part of the paper provides an overview of key concepts discussed in the literature on adult learning, including the characteristics of adult learners, self-directed learning, experiential learning, transformative learning, and adult learning in groups. The next part of the paper is focused specifically on collaborative inquiry as adult learning, reviewing the purposes, principles, process, and facilitation of such inquiry found in the knowledge base on adult learning. The third part of the paper reviews literature on successful teacher inquiry and describes …

Kinetics, Thermodynamics, And Biological Characterizations Of Hydrolysates Enzymatically Produced From Proteins Extracted From Microalgae, Hebah Al Amodi

Thesis/ Dissertation Defenses

This thesis aims to explore the use of Zeolitic Imidazolate Framework-L (ZIF-L) as a support for immobilizing alcalase and its potency in producing protein hydrolysates. ZIF-L was synthesized at room temperature using an aqueous solution, and alcalase was immobilized through adsorption batch experiment. The successful immobilization of alcalase on ZIF-L was confirmed through Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The maximum adsorption capacity of alcalase on ZIF-L was determined to be 672.1 ± 5.5 mg g-1 at 40°C using an initial protein concentration of 5 mg mL-1. Adsorption equilibrium data suggested …

The Function Of Memory In Understanding And Addressing Cultures Of Impunity, Veronica Jereza

Budhi: A Journal of Ideas and Culture

Recent psychological studies show that systemic oppression may be understood as trauma, which is aggravated in the context of a culture of impunity. Cultures of impunity, then, are a problem not only of legal justice and collective trauma but also of personal memory and its fragmentation. Following developments in trauma studies and Paul Ricoeur’s Memory, History, Forgetting and Lectures on Ideology and Utopia, cultures of impunity may be understood as an institutionalized forced forgetfulness with destructive and self-reinforcing effects on personal and collective memory. This paper aims to present a generic account of the function of memory in understanding and …

A Vision Of Hell: Walter Benjamin's Angelus Novus And The Catastrophe Of Progress, Pregiosa Regina Ang De Joya

Budhi: A Journal of Ideas and Culture

Before his untimely death in 1940, the German philosopher Walter Benjamin wrote an essay, entitled “Theses on the Philosophy of History,” marking his recovery from the shock of the Hitler-Stalin non-aggression pact. This study reflects on the philosophical and historical significance of this essay, unraveling Benjamin’s critique of Marxism as a critique of progress. Progress, which the angel of history sees as a storm coming from paradise, has caused a growing pile of rubble of historical blunders and environmental disasters. This uncritical submission to progress, however, can be seen not only in the blind confidence of the communists and the …

Byzantine And Early Islamic Faunal Remains From Building 900 In The Southern Tyropoeon Valley, Nimrod Marom

'Atiqot

The excavation in the western part of the City of David uncovered small assemblages of animal remains from the Byzantine and Early Islamic periods, attesting to similar consumption patterns in both occupation phases. The basic suite of domesticates is characteristic of urban settlements in late antiquity, comprising caprines, pigs and cattle, as well as fowl, and possibly fish. This varied diet points to the high-status of the inhabitants of the building.The public and commercial production of pork in the Early Islamic period is noteworthy.

A Treasure From Nahal Shalva: Exquisite Jewelry And A Coin Hoard From The Days Of The Bar Kokhba Revolt, Yael Abadi-Reiss, Gabriela Bijovsky, Shua Amorai-Stark, Naama Sukenik, Shoshana Israeli, Emil Aladjem

'Atiqot

A female skeleton adorned with unique jewelry items, and accompanied by a sword and cosmetic tools, was discovered within a pit at the site of Naḥal Shalva. Near the skeleton was a hoard of silver and gold coins from the days of the Bar Kokhba Revolt, which were kept in at least two linen purses. The hoard and its owner are the focus of this article, discussed in relation to the nearby settlement and the possible circumstances that led to their deposition at the site in the Early Roman period.

Religious Attitudes And Fear Toward Traditional Biomedical And Psychological Services Among People Of The Christian Faith, Brennan Cackett

Walden Dissertations and Doctoral Studies

Adults who identify as Christian often seek help within their religious communities for mental health issues. Research suggested that religious counseling services may discourage members from reporting mental health issues to traditional biomedical and psychological providers. The purpose of this quantitative study was to examine the extent to which people who identify as Christian in Southern California seek help outside of the Church and whether their help seeking is influenced by their religious attitudes and perceived fear of traditional psychological services. Southern California was chosen as it is where the Christian Counseling movement was started and has a large population …

Metabolic Scaling, Energy Allocation Tradeoffs, And The Evolution Of Humans’ Unique Metabolism, Andrew K. Yegian, Steven B. Heymsfield, Eric R. Castillo, Manfred J. Müller, Leanne M. Redman, Daniel E. Lieberman

Clinical Research Faculty Publications

All organisms use limited energy to grow, survive, and reproduce, necessitating energy allocation tradeoffs, but there is debate over how selection impacted metabolic budgets and tradeoffs in primates, including humans. Here, we develop a method to compare metabolic rates as quotients of observed relative to expected values for mammals corrected for size, body composition, environmental temperature, and phylogenetic relatedness. Contrary to previous analyses, these quotients reveal that nonhuman primates have total metabolic rates expected for similar-sized mammals in similar environments. In addition, data from several small-scale societies show that humans evolved exceptionally high resting, activity, and total metabolic rates apparently …

Casey Gill Named Vice President For Student Development And Chief Student Experience Officer, University Of Dayton

News Releases

Casey Gill, vice president for student development and dean of students at Wittenberg University, will become vice president for student development and chief student experience officer at the University of Dayton Jan. 1.

Evaluating The Multi-Valued Bartlett Processor, Daniel Robert Frister

Dissertations and Theses

A variety of approaches exist to track targets in the ocean using acoustic sensors, and the complex mix of source characteristics, environmental effects, and sensor array limitations can make the selection of an appropriate algorithm challenging. This thesis models in simulation a recently proposed signal processing method that is intended for use with a large rectangular sensor array to track the bearings of multiple sources. The method, referred to as the Multi-Valued Bartlett (MVB) processor, is an eigenvector beamformer that leverages the capabilities of large arrays to locate in bearing multiple sources simultaneously. The analysis of this thesis details the …

Friends With Social Benefits: Queerplatonic Relationships And The Future Of Marriage

Tennessee Journal of Race, Gender, & Social Justice

No abstract provided.

Characterising The Anxiogenic Network From Functional Connectivity Analysis Of The Co2 Challenge Model, Daniel Graham, Santra Mathew, Jonathan Marsden, Alastair D Smith, Gary Smerdon, Stephen D Hall

School of Psychology

The CO2 challenge model (CCM) is a gas inhalation paradigm that provides precisely controlled anxiety induction in experimental settings. Despite its potential as an experimental model of anxiety, our understanding of the neural effects of the CCM is incomplete. This study employs resting-state functional magnetic resonance imaging (rs-fMRI) to explore functional connectivity (FC) changes underlying the CCM. Following a preliminary CO2 tolerance assessment, participants completed an MRI session that included three rs-fMRI scans: during inhalation of control air (pre and post), and during a 6% CCM exposure. Here, we confirm that 6% CCM is a tolerable anxiogenic model in the …

Multiple Factors Regulate The Expression Of Sufcdsub In Streptococcus Mutans, Kassapa Ellepola, Lauren C. Guillot, Bradley Comeaux, Yiran Han, Jessica K. Kajfasz, Jacob P. Bitoun, Grace Spatafora, Jose A. Lemos, Zezhang T. Wen

School of Dentistry Faculty Publications

Introduction: The sufCDSUB gene cluster, encoding the sole iron-sulfur (Fe-S) cluster assembly system in S. mutans, was recently shown to be up-regulated in response to oxidative stressors and Fe limitation. Methods: In this study, luciferase reporter fusion assays, electrophoretic gel mobility shift assays (EMSA) and in vitro transcription assays (IVT) were used to dissect the cis- and trans-acting factors that regulate the expression of sufCDSUB. Results and discussion: Results showed deletion of perR, for the only Fur-family transcriptional regulator in S. mutans, resulted in > 5-fold increases in luciferase activity under the control of the sufCDSUB promoter (P < 0.01), as compared to the parent strain, UA159 when the reporter strains were grown in medium with no supplemental iron. Site-directed mutagenesis of a PerR-box in the promoter region led to elevation of the reporter activity by >1.6-fold (P < 0.01). In an EMSA, recombinant PerR (rPerR) was shown to bind to the cognate sufCDSUB promoter leading to mobility retardation. On the other hand, the reporter activity was increased by > 84-fold …

Genetic Manipulation Of Caveolin-1 In A Transgenic Mouse Model Of Aortic Root Aneurysm: Sex-Dependent Effects On Endothelial And Smooth Muscle Function, Tala Curry-Koski, Brikena Gusek, Ross M. Potter, T. B. Jones, Raechel Dickman, Nathan Johnson, John N. Stallone, Roshanak Rahimian, Johana Vallejo-Elias, Mitra Esfandiarei

Pacific Faculty Work

Marfan syndrome (MFS) is a systemic connective tissue disorder stemming from mutations in the gene encoding Fibrillin-1 (Fbn1), a key extracellular matrix glycoprotein. This condition manifests with various clinical features, the most critical of which is the formation of aortic root aneurysms. Reduced nitric oxide (NO) production due to diminished endothelial nitric oxide synthase (eNOS) activity has been linked to MFS aortic aneurysm pathology. Caveolin-1 (Cav1), a structural protein of plasma membrane caveolae, is known to inhibit eNOS activity, suggesting its involvement in MFS aneurysm progression by modulating NO levels. In this study, we examined the role of Cav1 in …

Student Comprehension Of Biochemistry In A Flipped Classroom Format, Ed Harris, Evan A. Schroder, Teryn J. Berks

Department of Biochemistry: Faculty Publications

Concept-heavy courses such as Biochemistry in life and physical science curricula are challenging for many college-aged students. It is easy for students to disengage in a lecture and not learn the subject matter while in class. To improve student learning and participation, we employed a flipped format for the first half of the course and compared learning outcomes and attitudes with the traditional lecture in the second half of the course. The experimental course was an upper-level biochemistry course taken primarily by juniors (49%), seniors (40%), and some graduate students (10%) at the college level. Our results indicate that lower-performing …

Antithrombotic Efficacy And Bleeding Risks Of Vaccine-Induced Immune Thrombotic Thrombocytopenia Treatments, Halina H.L. Leung, Zohra Ahmadi, Brendan Lee, John Casey, Sumita Ratnasingam, Steven E. Mckenzie, Jose Perdomo, Beng H. Chong

Cardeza Foundation for Hematologic Research

Current guidelines for treating vaccine-induced immune thrombotic thrombocytopenia (VITT) recommend nonheparin anticoagulants and IV immunoglobulin (IVIg). However, the efficacy of these treatments remains uncertain due to case studies involving small patient numbers, confounding factors (eg, concurrent treatments), and a lack of animal studies. A recent study proposed danaparoid and heparin as potential VITT therapies because of their ability to disrupt VITT IgG-platelet factor 4 (PF4) binding. Here, we examined the effects of various anticoagulants (including unfractionated [UF] heparin, danaparoid, bivalirudin, fondaparinux, and argatroban), IVIg, and the FcγRIIa receptor-blocking antibody, IV.3. Our investigation focused on VITT IgG-PF4 binding, platelet activation, thrombocytopenia, …

Sustainable Environmental Technologies: Recent Development, Opportunities, And Key Challenges, Prafulla Kumar Sahoo, Rupali Datta, Mohammad Mahmudur Rahman, Dibyendu Sarkar

Michigan Tech Publications

No abstract provided.

Gut Microbiota Profiling In Injection Drug Users With And Without Hiv-1 Infection In Puerto Rico, Nirosh Aluthge, Seidu Adams, Carmen A. Davila, Nova R. Gocchi Carrasco, Kathy S. Chiou, Roberto Abadie, Sydney J. Bennett, Kirk Dombrowski, Angel M. Major, Aníbal Valentín-Acevedo, John T. West, Charles Wood, Samodha C. Fernando

School of Medicine Faculty Publications

INTRODUCTION: The full extent of interactions between human immunodeficiency virus (HIV) infection, injection drug use, and the human microbiome is unclear. In this study, we examined the microbiomes of HIV-positive and HIV-negative individuals, both drug-injecting and non-injecting, to identify bacterial community changes in response to HIV and drug use. We utilized a well-established cohort of people who inject drugs in Puerto Rico, a region with historically high levels of injection drug use and an HIV incidence rate disproportionately associated with drug use. METHODS: Using amplicon-based 16S rDNA sequencing, we identified amplicon sequence variants (ASVs) that demonstrated significant variations in the …

Comparing Neoantigen Cancer Vaccines And Immune Checkpoint Therapy Unveils An Effective Vaccine And Anti-Trem2 Macrophage-Targeting Dual Therapy, Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Tomoyuki Minowa, Martina Molgora, Charmelle D Williams, Mehdi Chaib, Anna M Highsmith, Josué E Pineda, Sayan Alekseev, Elise Alspach, Kenneth H Hu, Marco Colonna, Kristen E Pauken, Ken Chen, Matthew M Gubin

Faculty, Staff and Student Publications

The goal of therapeutic cancer vaccines and immune checkpoint therapy (ICT) is to promote T cells with anti-tumor capabilities. Here, we compared mutant neoantigen (neoAg) peptide-based vaccines with ICT in preclinical models. NeoAg vaccines induce the most robust expansion of proliferating and stem-like PD-1+TCF-1+ neoAg-specific CD8 T cells in tumors. Anti-CTLA-4 and/or anti-PD-1 ICT promotes intratumoral TCF-1- neoAg-specific CD8 T cells, although their phenotype depends in part on the specific ICT used. Anti-CTLA-4 also prompts substantial changes to CD4 T cells, including induction of ICOS+Bhlhe40+ T helper 1 (Th1)-like cells. Although neoAg vaccines or ICTs expand iNOS+ macrophages, neoAg vaccines …

Septal Wall Synthesis Is Sufficient To Change Ameba-Like Cells Into Uniform Oval-Shaped Cells In Escherichia Coli L-Forms, Masafumi Hayashi, Chigusa Takaoka, Koichi Higashi, Ken Kurokawa, William Margolin, Taku Oshima, Daisuke Shiomi

Faculty, Staff and Student Publications

A cell wall is required to control cell shape and size to maintain growth and division. However, some bacterial species maintain their morphology and size without a cell wall, calling into question the importance of the cell wall to maintain shape and size. It has been very difficult to examine the dispensability of cell wall synthesis in rod-shaped bacteria such as Escherichia coli for maintenance of their shape and size because they lyse without cell walls under normal culture conditions. Here, we show that wall-less E. coli L-form cells, which have a heterogeneous cell morphology, can be converted to a …