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Appalachia Winter/Spring 2006: Complete Issue

Appalachia

No abstract provided.

Evaluating The Effect Of Chemotherapy Notch1 Gene Expression In Patients With Prostate Cancer, Mustafa S. Khudhur, Ali Adil Majeed

Al-Ameed Journal for Medical Research and Health Sciences

This study was conducted on 50 cases of prostate cancer patients and 20 apparently healthy. The study analyzed the distribution of prostate cancer (PC) patients across various categories. Significant differences were observed in group grades, Gleason scores, cell grades, stages, and dose names. The mean age of the patient cohort was 67.84 years with a median diagnosis time of 7 years. Laboratory assays including measurements of red blood cells count, platelet count, white blood cells count, and prostate specific antigene levels. The mean total chemotherapy dose received by patients was 1708.28. Significant differences were found in the distribution of group …

Learning As A Child In Gopnik's The Philosophical Baby, Christopher Joseph An

Budhi: A Journal of Ideas and Culture

Learning as a Child in Gopnik's The Philosophical Baby

Gareth Matthews And The Philosophy Of Childhood, Marella Ada V. Mancenido-BolañOs

Budhi: A Journal of Ideas and Culture

Gareth Matthews and the Philosophy of Childhood

America: The Janus Nation, Peter Murphy

Budhi: A Journal of Ideas and Culture

America is a paradoxical society. That is one of its strengths. One of its weaknesses is its periodic inability to understand its own paradoxical nature. It is a Janus nation, one in which (in principle) incompatible things exist in a simultaneous state. When this paradoxical fusion works, it has great benefits. When it fails to work, American society loses its inner equilibrium. Pugnacious antagonisms arise in its place. The tension within the United States between the drive toward a union of opposites (most famously embodied in its Constitution) and the periodic centrifugal spinning out of American society into a state …

The Androgynous Baglan: Interruption, Withdrawal, And Reclaiming, Aurelio S. Agcaoili

Budhi: A Journal of Ideas and Culture

The pursuit of decolonization is a first act in the manifold acts of real, because substantive, liberation of a colonized country like the Philippines. The reason is clear: every colonizer not only colonizes a country but invades and occupies the mind of the people of that country, puts a claim to their bodies, and replaces their language and cultural practices with his own to complete his violent act of “discovering” the Other. Even with independence granted to a colonized people, the intellectual residues in a colonized consciousness that has coopted with the colonizer if only to survive continue to haunt, …

How To Love In Easy Steps: Heteronormativity, Queer Love, And Foucault's Counter-Conduct, Hannah Jane S. Carpiso, Ninotchka Mumtaj B. Albano

Budhi: A Journal of Ideas and Culture

Love is one of the most pervasive human experiences, yet its definition remains elusive to this day. Attempts to describe love have led to the institutionalization and privileging of heterosexual identities, relationships, and ways of loving. Michael Warner refers to this phenomenon as “heteronormativity,” which rigidifies subjectivities and relationalities into fixed, heterosexist structures. However, queer love unfolds in ways different from this relational structure. It invents and re-invents love, relationalities, and subjectivities by moving beyond the dichotomies of heteronormativity. The inventive characteristic of queer love is found in what is known as the “gay mode of life,” an instance of …

Book Review: The Mindset Of A Dyslexic Entrepreneur: The Scott Holman Story By Don Steele, Russell Magnaghi

Upper Country: A Journal of the Lake Superior Region

No abstract provided.

Ai: A New Lone-Wolf Terrorism In The Digital Era (Preliminary Analysis), Marthsian Yeksi Anakotta Mya

Journal of Terrorism Studies

This article addresses two fundamental inquiries: can AI engage in acts of terrorism? If so, how might such a phenomenon occur? My hypothesis posits that AI is capable of independently committing acts of terrorism, a classification derived from the study of terrorism known as lone-wolf terrorism. To address these dual issues, this article adopts a criminological approach, which is further elaborated through an examination of lone-wolf terrorism and the advancement of artificial intelligence. As is widely recognized, contemporary terrorist organizations have harnessed technological advancements in the realm of information and communication to perpetrate acts of terrorism within the digital sphere. …

Rai, Shaunna, Kylie Cloutier

Querying the Past: LGBTQ Maine Oral History Project Collection

Shaunna Rai, or Daniel Shackley, was born in Killeen, Texas in 1972 to a military family and moved near the Augusta, Maine area during their school years. They grew up as a cisgender man in Bridgeton, Maine and attended Lakes Region High School. Shaunna fathered a child as a teen in high school and is now a grandparent. Shaunna moved out to live independently at 16 and utilized the group Outright! In the Lewiston/Auburn area as a support group for LGBTQ+ youth. Shaunna discovered drag in their early 20’s because of roommates, friends, and the active gay bar scene in …

Finding Them Before They Find Us: Solving The Emerging Infectious Disease Crisis, Daniel R. Brooks

MANTER: Journal of Parasite Biodiversity

The human population grows daily, it’s on the move, and it’s carving a deep technological footprint on our planet. We alter landscapes and perturb ecosystems, inserting ourselves and other species into novel regions of the world, leading to potentially irreversible changes in the biosphere. This is not news. More than 75 years ago, Charles Elton, one of the founders of modern ecology, wrote, “We must make no mistake; we are seeing one of the greatest historical convulsions in the world’s fauna and flora.” We are also in the midst of a public health and epidemiological crisis. Climate change alters movements …

“Before, We Didn’T Eat Manioc Flour”: Historical And Social Transformations In Food Techniques Among Indigenous Peoples Of The Rio Negro Basin In The Brazilian Amazon, Lorena França

Tipití: Journal of the Society for the Anthropology of Lowland South America

Manioc flour is currently considered one of the main foods consumed by Indigenous peoples in the Northwest Amazon. It is fundamental both to the traditional diet and to adding an "Indigenous flavor" to urban dishes. This article presents an analysis of historical sources that position manioc flour as an important trading commodity since the 19th century and shows how its internal consumption seems to have grown in recent decades. This significance contrasts with the role of manioc flour in mythic narratives about the origin of foods, where it is either not mentioned among the Tukano peoples or referred to as …

“We Will Fight For Them”: The Defense Of The ´Isolated´ Piriti People By The Waimiri Atroari, Amazonas And Roraima, Brazil, Silvia Melo Futada, Walter Nicanor Fontoura Blos, Antônio Carlos Andrade Do Nascimento, Marcelo De Sousa Cavalcante, Glenn H. Shepard Jr, Waimiri Atroari Community Association (Acwa)

Tipití: Journal of the Society for the Anthropology of Lowland South America

The Pirititi are a little known ´isolated´ Indigenous group occupying a highly threatened territory on the border between Amazonas and Roraima states in Brazil who have rejected all previous attempts at contact and encounter. The Waimiri Atroari previously had conflicts with the Pirititi, who occupy a contiguous area, but over the past decade have taken it upon themselves to defend the Pirititi and their territory, relying mostly on their own resources. Given the slow pace of official Brazilian governmental responses to land invasions and other threats to the Pirititi, the Waimiri Atroari have become the main protagonists of protection and …

Uneven Burdens: The Intersection Of Brownfields, Pollution, And Socioeconomic Disparities In New Jersey, Usa, Shih-Chieh Chien, Charles Knoble

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Brownfields, abandoned or underutilized lands having the potential for contamination due to industrial activities, pose health risks to nearby residents and raise environmental justice (EJ) concerns. This study examines the relationship between brownfield distribution and socioeconomic factors in New Jersey, a state with over 700 brownfield sites, using correlation, spatial autoregression, and instrumental variable regression methods. Results show that brownfields are associated with higher combined EJ stressors, indicating compounding environmental pollution and health risks in affected areas. Brownfields are disproportionately correlated with lower household income, higher rates of uninsured individuals, lower educational attainment, and a greater percentage of people of …

Assessing Knowledge And Preventive Practices Regarding Infectious Diseases Among Healthcare Workers In Hail City, Saudi Arabia, Sandro Costanilla Villareal

Jurnal Keperawatan Indonesia

Studies suggest that there may be gaps in knowledge and compliance with infection control measures among healthcare workers in Saudi Arabia. This study aimed to determine the knowledge of, and preventive measures employed by the healthcare workers in Hail City, Saudi Arabia, regarding infectious diseases. A cross-sectional design was employed, and the study participants were 265 healthcare workers aged 18 or older who were currently employed at government hospitals, involved in patient care or essential healthcare services, and fluent in English. Healthcare workers on leave, with cognitive impairments, with language barriers, or who refused to participate in the study were …

Opa1 And Disease-Causing Mutants Perturb Mitochondrial Nucleoid Distribution, J. Macuada, I. Molina-Riquelme, G. Vidal, N. Pérez-Bravo, C. Vásquez-Trincado, G. Aedo, D. Lagos, P. Yu-Wai-Man, R. Horvath, T. J. Rudge, B. Cartes-Saavedra, V. Eisner

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Optic atrophy protein 1 (OPA1) mediates inner mitochondrial membrane (IMM) fusion and cristae organization. Mutations in OPA1 cause autosomal dominant optic atrophy (ADOA), a leading cause of blindness. Cells from ADOA patients show impaired mitochondrial fusion, cristae structure, bioenergetic function, and mitochondrial DNA (mtDNA) integrity. The mtDNA encodes electron transport chain subunits and is packaged into nucleoids spread within the mitochondrial population. Nucleoids interact with the IMM, and their distribution is tightly linked to mitochondrial fusion and cristae shaping. Yet, little is known about the physio-pathological relevance of nucleoid distribution. We studied the effect of OPA1 and ADOA-associated mutants on …

Accounting For Post-Release Mortality In Data-Limited, Length-Based Assessments For Four Demersal Fish Species With Varying Life Histories, Brett Crisafulli, Sybrand A. Hesp, Ebenezer Afrifa-Yamoah, Ute A. Mueller, Karina L. Ryan, David V. Fairclough, Norman G. Hall, Johnny Lo

Fisheries Research Articles

Released (or discarded) fish from recreational and commercial line fisheries can experience significant levels of post-release mortality (PRM), affecting sustainability. Although PRM effects are often considered in data-rich (integrated model) assessments, this is uncommon in data-limited assessments. This study investigates impacts of PRM when applying data-limited, length-based assessment methods for four reef-dwelling demersal fish species in temperate Western Australia (Glaucosoma hebraicum, Chrysophrys auratus, Choerodon rubescens and Epinephelides armatus). These species differ considerably in their biology and susceptibility to PRM. For each species simulations were undertaken to (1) evaluate the reliability of a length-based catch curve (LBCC) …

Terrorist Financing In The Digital Age: An Analysis Of Crypto Currencies And Online Crowd Funding, Eziho Promise Ogele

Journal of Terrorism Studies

This study examines the potential risks of emerging payment technologies and value transfer systems in facilitating terrorist activities. Through an analysis of publications, blogs, and websites associated with terrorist groups and their supporters, the research reveals a growing interest in leveraging cryptocurrencies like Bitcoin and online crowdfunding platform to support funding, planning, and implementation of terror attacks. While concrete evidence of large-scale cryptocurrency use by terrorist groups is limited, there are indications of links to several terror attacks globally. This study demonstrates the potential for cryptocurrencies to facilitate clandestine activities, utilizing a document published by ISIS that outlines instructions undetected. …

Characterization And Performance Nanofiltration Membranes In Water Quality For Goldfish (Carassius Auratus) Aquaculture, Inpita Casuarina Eqisetia Utari, Uun Yanuhar, Asus Maizar Suryanto Hertika, Heru Suryanto, Jibril Maulana, Nico Rahman Caesar, Mahrus Ismail, Leong-Seng Lim

Journal of Mechanical Engineering Science and Technology (JMEST)

Water quality is an important factor in aquaculture activities, including goldfish (Carassius auratus) farming. One approach to improving water quality is the use of nanofilters. This study aims to evaluate the performance of nanofilters made from Sargassum sp. with the addition of copper oxide nanoparticles. The method used involves the fermentation of bacterial cellulose from Acetobacter xylinum using Sargassum sp. extract as a medium, followed by homogenization and the addition of CuO-NPs at concentrations of 0.5%, 1%, and 1.5%, and subsequent oven drying. The nanofilter membrane will then be analyzed using SEM, XRD, and FTIR to characterize its properties. Performance …

Family Perceptions Of Palliative Care For Advanced-Stage Cancer Patients At Home, Mariam Dasat, Sigit Mulyono, Uswatul Khasanah, Stepanus Maman Hermawan

Jurnal Keperawatan Indonesia

Family assistance with palliative care for advanced cancer patients is very important in optimizing patients’ quality of life. The purpose of this study was to explore family perceptions of palliative service provision to advanced cancer patients at home. The study adopted a qualitative research design with a phenomenological approach based on in-depth interviews with six participants. The main theme that emerged was family perceptions of participation in palliative care programs for cancer patients at home. There were three subthemes: family administering additional treatment, the patient being resigned to and accepting their condition, and the patient being helped by treatment. The …

Waves Of Flickering Murmurs In Everyday Life: Playing Between Ages, Joanna Haynes, Jan Georgeson, Karen Wickett, Mandy Andrews, Dani Landau, Kathrin Paal, Emma Bush, Magda Costa Carvalho, Viktor Johansson, Tiago Almeida, Lois Peach, Giovanna Caetano-Silva, Rose-Anne Reynolds, Bakhtawar Khosa, Patricia Hannam, Arthur C Wolf, Claudia Blandon, Georgios Petropoulos, Hanna Oester-Barkey

School of Law, Humanities and Social Sciences

The article explores the rich and varied experiences of a collective writing project, unfolding through an anecdote involving Charlie, a young boy who creatively disrupted conventional pho-tography methods. This incident, during an evening promenade by the sea in Ericeira (Portugal), epitomizes the project's embrace of playfulness and exploration of diverse perspectives—materialized through Charlie's playful insistence on experimenting with different angles. The event embodied the group’s approach to writing, leading to a collective inquiry into the interplay of ages, angles, and other themes like waves, threads, shadows, and liminal spaces. The project, driven by the Between Ages Collective, began with informal …

Synthesis And In Vitro Testing Of Mg-6zn-Xhap Biocomposites From Beef Bone As Biodegradable Bone Implant Material, Jojor Lamsihar Manalu, Francisca Tjhay, Theodora Kristoforus, Sovian Aritonang

Journal of Mechanical Engineering Science and Technology (JMEST)

This study aimed to develop biodegradable Mg-6Zn hydroxyapatite (Mg-6Zn HAp) biocomposites for potential use in bone replacement applications. The hydroxyapatite (HAp) powders, sourced from cow bone, were synthesized through an eco-friendly and cost-effective process, leveraging bioresources for material sustainability. The Mg-6Zn and HAp powders were mechanically mixed through ball milling for six hours to ensure homogeneity. The resultant powder mixture was then subjected to isostatic pressing at a high pressure of 570 MPa, forming a dense coin-shaped composite with a 1.5 cm diameter. This coin was consolidated in a capsule furnace at elevated temperatures for one hour to enhance material …

Characterization Of Hydroxyapatite Derived From Scallop Shell Waste Synthesized By Sonochemical Method With Different Temperature Calcination, Diki Dwi Pramono, Poppy Puspitasari, Aminnudin Aminnudin, Jeefferie Abd Razak

Journal of Mechanical Engineering Science and Technology (JMEST)

One common bio-ceramic material used in the biomedical industry is hydroxyapatite. Because of its crystallographic and molecular resemblance to the hard tissues of the human body, hydroxyapatite is thought to form. Scallop shells are one natural source of hydroxyapatite, which is high in calcium. This study examines how the calcination temperature affects the characteristics of hydroxyapatite made from leftover scallop shell. Hydroxyapatite was synthesized via the sonochemical method, with calcination conducted at temperatures of 900°C, 1000°C, and 1100°C. The hydroxyapatite that was prepared was assessed using Xray diffraction (XRD) to determine the phase and crystallite size, Scanning Electron Microscopy (SEM) …

Analysis Of Titanium Mesh Ti6al4v Formation Using Die Press Forming Machine For Cranioplasty, Ahmad Ayyub Syaiful Rizal, Mahros Darsin, Robertoes Koekoeh K. Wibowo, Khairul Anam

Journal of Mechanical Engineering Science and Technology (JMEST)

Cranioplasty is required for patients with head defects, where the deformed part of the head is replaced with Ti6Al4V titanium wire implants. The titanium wire forming process is usually done manually, which can take a long time and give results that do not match the anatomical shape of the head. Therefore, it is important to develop domestic technology that can produce titanium wire automatically. This study aims to analyze the frame and mold of the automatic wire mesh molding machine before production. The tool is made using press forming method and finite element analysis with ANSYS software. The machine frame …

From Shocks To Solidarity And Superstition: Exploring The Foundations Of Faith, Aidin Hajikhameneh, Laurence R. Iannaccone

ESI Publications

Additive shocks can substantially increase cooperation in otherwise standard public goods game experiments. We study shocks that randomly adjust players’ earnings by a fixed positive or negative amount reported at the end of each round. These adjustments change neither the return to players’ contributions nor the information about other group members. We compare results across four treatments that employ the same group-level adjustment algorithm but frame it differently, with pre-play descriptions that range from omitting all useful information to accurately revealing its 50/50 random nature. In each treatment, overall contributions run about 50% higher than those obtained in the standard …

Carbon And Biodiversity Co-Benefits In Tropical Forest And Agroforestry Ecosystems: A Review, Anna N Mwambala

Tanzania Journal of Science

Global efforts to mitigate climate change are focused on the protection and restoration of forest carbon. These efforts do not only hold promise for climate protection but also other benefits including conservation of biodiversity, the majority of which is sheltered in the forest. These include actions to combat climate change and land degradation and actions to halt biodiversity loss through sustainable forest management. However, the challenge remains as to what extent forest conservation that optimizes carbon storage will conserve biodiversity. Understanding synergies between climate change mitigation and biodiversity conservation could be the basis for attaining sustainable development goals. Library catalogues …

Mammalian Mitochondrial Inorganic Polyphosphate (Polyp) And Cell Signaling: Crosstalk Between Polyp And The Activity Of Ampk, Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, Maria E. Solesio

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

UNLABELLED: Inorganic polyphosphate (polyP) is an evolutionary and ancient polymer composed by orthophosphate units linked by phosphoanhydride bonds. In mammalian cells, polyP shows a high localization in mammalian mitochondria, and its regulatory role in various aspects of bioenergetics has already been demonstrated, via molecular mechanism(s) yet to be fully elucidated. In recent years, a role for polyP in signal transduction, from brain physiology to the bloodstream, has also emerged.

OBJECTIVE: In this manuscript, we explored the intriguing possibility that the effects of polyP on signal transduction could be mechanistically linked to those exerted on bioenergetics.

METHODS: To conduct our studies, …

Lifestyle, Values, And The Meaning Of Life, Ashok Vohra

Budhi: A Journal of Ideas and Culture

There are alternative lifestyles. We choose the one which in our opinion will help us to fulfill our voluntarily chosen purpose or meaning of our life. The paper explores the meaning of “meaning of life.” To understand the notion of meaning of life, I have made an exhaustive and critical survey of the philosophical literature of both Eastern and Western philosophy. I have argued that one finds the meaning of one’s life and fulfills it, if and only if one follows one’s true nature and does not blindly follow what others are doing.

Chiron And The Machines Of Loving Grace: On Optimism, Pessimism, And Singularity, John T. Giordano

Budhi: A Journal of Ideas and Culture

Singularity has been a concern of the developers of cybernetics and artificial intelligence (AI) since the pioneering writings of such thinkers as Norbert Weiner. Yet many accept the inevitability of systems of AI surpassing human control and are optimistic that machine intelligence will harmonize human life with our environment. This essay examines this optimism against a reading of two poets: Richard Brautigan and Friedrich Hölderlin. Through these readings, it will attempt to show that the eclipse of nature by human beings can be used to examine the eclipse of the human being by machine intelligence. Thus, what is missing in …

Exploring The Philosophy Of Development Through UexküLl's Notion Of Umwelt, Yuhi Fujita

Budhi: A Journal of Ideas and Culture

This paper aims to depict the development of human beings as a transformative relationship between individuals and their world. Anchored on Uexküll’s concept of the environment, “Umwelt,” and further developed through the works of Heidegger, Kokubun, and Merleau-Ponty, I present the relationship between man and the world through the formation of the world and the movement of organisms between Umwelts. For Heidegger, humans live while forming their own world whereas animals can only be “poor in world.” Kokubun further emphasizes that human beings live while moving through various Umwelts. But according to Merleau-Ponty, human bodies reconfigure their fields of action, …