Digital Commons Network^™

Cellular Trafficking And Fate Mapping Of Cells Within The Nervous System After In Utero Hematopoietic Cell Transplantation, Matthew T Grant, Hemanth Ramesh Nelvagal, Maria Tecos, Amal Hamed, Kerry Swanson, Jonathan D Cooper, Jesse D Vrecenak

2020-Current year OA Pubs

In utero hematopoietic cell transplantation (IUHCT) utilizes fetal immune tolerance to achieve durable chimerism without conditioning or immunosuppression during a unique window in fetal development. Though donor cells have been observed within the nervous system following in utero injection, the timeline and distribution of cellular trafficking across the blood-brain barrier following IUHCT is not well understood. We injected 20 × 10

A Modeling Framework For Flocculated Cohesive Sediment Transport In The Current Bottom Boundary Layer, Jorge A. Penaloza-Giraldo, Liangyi Yue, Tian Jian Hsu, Bernhard Vowinckel, Andrew Manning, Eckart Meiburgc

School of Biological and Marine Sciences

Cohesive sediment transport, where its settling velocity is controlled by the flocculation process, is a crucial component in determining biochemical cycles, fate of pollutants, and morphodynamics in many aquatic ecosystems. In this study, a modeling framework is presented to investigate how flocculation influences cohesive sediment transport in the current bottom boundary layer in dilute conditions, consistent with the calibration range of the flocculation model. From a local analysis of floc dynamics in homogenous turbulence, we identify that the floc size distribution is mainly controlled by floc cohesion and yield strength. The uncertainty in fractal dimension plays a minor role for …

How To Design A Program For The Poor That Is Not A Poor Program: Explaining The Political Sustainability Of The Guaranteed Income Supplement, Daniel Béland, Patrik Marier

Osgoode Hall Law Journal

Created in 1967 as a temporary program aimed at supporting low-income people during the maturation of the Canada and Quebec Pension Plans, the Guaranteed Income Supplement (GIS) has since become a permanent policy that remains a central component of Canada’s multi-layered public pension system. In this article, we explain why GIS is a popular and politically successful program that challenges the common wisdom in political science and policy analysis that “programs for the poor are poor programs.” The article shows that the success of GIS stems from its policy design (e.g., income-tested rather than means-tested benefits), the social construction of …

The Canada Disability Benefit Act And Women With Disabilities: Pursuing Disability Equality And Reducing Administrative Violence, Laverne Jacobs

Osgoode Hall Law Journal

Stakeholders have welcomed the Canadian Disability Benefits Act as an opportunity to rectify the long-standing socioeconomic disadvantage experienced by persons with disabilities. This article examines one specific form of marginalization that lies beneath the surface of the discussions surrounding poverty and persons with disabilities in Canada: It considers women with disabilities and disabled women from intersecting backgrounds, who face unique experiences of poverty that need to be addressed by any legislation aiming to eradicate income barriers for the disability community. By drawing on the theoretical frameworks of bureaucratic disentitlement, administrative violence, and disability equality, this article examines the lived realities …

Effect Of Yoga Therapy For Managing Migraine: A Case Series, Andrea Moran, Lori Rubenstein Fazzio

Journal of Applied Yoga Studies

Migraine is a common disabling primary headache disorder. It is characterized by symptoms lasting 4-72 hours, headache with unilateral location, pulsating quality, moderate or severe intensity, aggravation by routine physical activity, and association with nausea and/or photophobia and phonophobia. In this case series four females in the age range of 25-57 presented complaints of migraine headaches affecting their everyday lives. Additionally, they reported emotional challenges accompanying chronic pain due to migraine headaches such as stress, sleep deprivation, and anxiety. An online eight-week yoga therapy program was given for the management of migraine headaches. This program included lifestyle modifications, postures, breathing …

News From The Chapters 1999-2000, C. Nicholas Raphael

The Geographical Bulletin

News from the Chapters 1999-2000

Timss 2023 Australia: Highlights On Australian Student Performance, Nicole Wernert, Marina Schmid, Sima Rodrigues

TIMSS 2023

Australia participated in the eighth cycle of the Trends in International Mathematics and Science Study (TIMSS). TIMSS is an international sample study that assesses the mathematics and science achievement of Year 4 and Year 8 students every 4 years. Australia has participated in all cycles of TIMSS since it commenced in 1995 and over this 28-year period has collected rich data about trends in mathematics and science achievement. TIMSS 2023 expanded its scope to assess environmental knowledge and attitudes. This new component provides valuable insights into students’ understanding of environmental issues, including climate change, biodiversity, and conservation. This Highlights report …

Timss 2023 Australia. Volume 1: Student Performance, Nicole Wernert, Marina Schmid, Sima Rodrigues

TIMSS 2023

The Trends in International Mathematics and Science Study (TIMSS) is an international comparative study of student achievement directed by the International Association for the Evaluation of Educational Achievement (IEA). TIMSS was first conducted in 1995 and the 2023 assessment formed the eighth cycle, providing 28 years of trends in mathematics and science achievement at Year 4 and Year 8. In Australia, TIMSS is managed by the Australian Council for Educational Research (ACER) and is jointly funded by the Australian Government and the state and territory governments. TIMSS is a key part of Australia’s National Assessment Program. The goal of TIMSS …

Cascon 2024, College Of Arts And Sciences

SHU Faculty Publications

No abstract provided.

Healthcare For Everyone: The Critical Role Of Medical Care In Society, Ana Fernandez

INRW/Coreq Student Showcase

Summer/Fall 2024 Student Showcase

Sk609, A Novel Dopamine D3 Receptor Agonist And Norepinephrine Transporter Blocker With Putative Pro-Cognitive Actions, Does Not Induce Psychostimulant-Like Increases In Risky Choice During Probabilistic Discounting, Christopher P. Knapp, Brooke Fallon, Sandhya Kortagere, Barry D. Waterhouse, Stan B Floresco, Rachel L Navarra

Rowan-Virtua School of Osteopathic Medicine Departmental Research

RATIONALE: Psychostimulants, such as amphetamine (AMPH) and methylphenidate (MPH), non-selectively elevate extracellular concentrations of the catecholamine neurotransmitters, dopamine (DA) and norepinephrine (NE), and are common pharmacological strategies used to improve prefrontal cortex (PFC)-dependent cognitive dysfunction. However, this approach can be problematic given AMPH has been shown to increase preference for risky choices in a rodent assay of risk/reward decision making. SK609 is a novel NE reuptake blocker that selectively activates DA D3 receptors without affinity for the DA transporter. SK609 has been shown to improve cognitive performance without increasing psychostimulant-like spontaneous locomotor activity, suggesting SK609 may benefit neurocognitive function without …

Strategies For Driver Retention At Small Trucking Companies, Dariell Kendrick Cooper

Walden Dissertations and Doctoral Studies

The trucking industry faces a critical driver shortage, which threatens the stability of supply chains and the economy at large. This issue is particularly challenging for owners of small trucking companies, as they form the backbone of the industry. Grounded in Herzberg’s two-factor theory and Maslow’s hierarchy of needs theory, this qualitative pragmatic inquiry aimed to identify the strategies small trucking company owners used to retain drivers and sustain their operations. The participants included five small trucking company owners from the southeastern United States. Data were collected through semistructured interviews, public records, and company websites. Thematic analysis was used to …

Perceptions And Attitudes Of Western Michigan University Students On Antibiotic Medications, Emily Boask

Honors Theses

On a global scale, antibiotic resistance is a threat to public health. The causes of antibiotic resistance are multifaceted, including healthcare providers overprescribing antibiotics, antibiotic overuse in farming and food production, and antibiotic misuse or malpractices. The public recognizes antibiotic resistance as a significant problem but there are serious knowledge gaps regarding antibiotic resistance and antibiotic stewardship.

University students are a particularly important subpopulation of the public to understand appropriate antibiotic use because many of these individuals are navigating their health concerns on their own for the first time. Many individuals believe that antibiotics can improve cold symptoms, upper respiratory …

December 4, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Modern Bodies: Globalizing Media Cultures And The Representation Of Ideal Beauty, Michelle Sun

Comparative Literature Undergraduate Senior Theses

This project aims to examine how the image of the “modern body” is constructed, imagined, modified, and sustained by globalizing media cultures in France, Japan, and the US—investigating how factors of race, age, health, class, and gender overlap and intersect to create a vision of “ideal” beauty across different times and spaces. Previous research has focused on particular topics, such as the rise of cosmetic surgery in East Asia or the politics of modern American beauty parlors. However, my goal in this project is to evaluate these diverse studies through a broader and more comparative lens, analyzing examples of French …

A Review Of The Association Between Dietary Intake And Brain Iron Levels In Older Adults: Preliminary Findings And Future Directions., Valentinos Zachariou, Christopher E. Bauer, Colleen A. Pappas, Brian T. Gold

Behavioral Science Faculty Publications

Background/Objectives: Non-heme iron is essential for critical neuronal functions such as ATP generation, synaptogenesis, neurotransmitter synthesis, and myelin formation. However, as non-heme iron accumulates with age, excessive levels can contribute to oxidative stress, potentially disrupting neuronal integrity and contributing to cognitive decline. Despite growing evidence linking high brain iron with poorer cognitive performance, there are currently no proven methods to reduce brain iron accumulation in aging or to protect cognitive function from iron’s negative effects. Recent studies suggest that nutrition may influence brain iron levels, though the evidence remains limited and mixed. Methods: In this review, we explore recent findings, …

University Of Richmond Symphony Orchestra, Department Of Music, University Of Richmond

Music Department Concert Programs

No abstract provided.

Consistency And Flexibility Of Character In Free-Ranging Male African Elephants Across Time, Age, And Social Contexts, Caitlin E. O’Connell-Rodwell, Jodie L. Berezin, Colleen Kinzley, Patrick T. Freeman, Monica N. Sandri, Dustin Kieschnick, Timothy C. Rodwell, Mariana Abarca, Virginia Hayssen

Biological Sciences: Faculty Publications

Post-dispersal male African elephants (Loxodonta africana) live within complex social networks. To quantify the consistency of male elephant character (or personality) within these networks, we employed behavioral repeatability analysis tools across social and environmental contexts. We collected behavioral data from thirty-four individually-identified male elephants at the same waterhole over five field seasons (2007–2011) in Etosha National Park, Namibia. Using repeatability models to assess ten behavioral categories, we found five behaviors (affiliation, aggression, dominance, self-directed anxious, and self-directed comfort) were consistent at the individual level. Some of these behaviors were also repeatable, depending on social context. In particular, the …

Glutamate Receptors At The Zebrafish Neuromuscular Junction, Trenton Randall

Honors College Theses

Glutamate is the main excitatory neurotransmitter in the CNS, but at the neuromuscular junction, that role is taken by acetylcholine. However, during embryonic development, non-cholinergic receptors, including those for glutamate, are also present at the NMJ, which are not maintained unless used. These receptors can still form functional circuits, as evidenced by a process called neurotransmitter respecification, in which a neuron changes which neurotransmitter it releases, and is accompanied by the upregulation of the corresponding receptor by the muscle. This process has been observed in frogs and in rats. We predict that zebrafish also exhibit this neurotransmitter plasticity. To assess …

Multicenter Clinical Performance Evaluation Of The Neumodx™ Ct/Ng Assay 2.0, B. Van Der Pol, A. Avery, Stephanie N. Taylor, J. Miller, C. L. Emery, A. English, G. B. Lazenby, Rebecca Lillis, J. Ruth, D. Young, S. Young, S. Chavoustie, L. Crane, V. Reid, G. Wall, S. Johnson

School of Medicine Faculty Publications

Background: Given the continued increases in rates of both Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection, additional diagnostic assays may be useful in increasing access to testing for these sexually transmitted infections. We evaluated the performance of the NeuMoDx™ CT/NG Assay 2.0 on the NeuMoDx-96 and NeuMoDx-288 Molecular Systems. Methods: The clinical sensitivity and specificity of the assay was assessed when used with: 1) endocervical swabs; 2) self-, and clinician-collected vaginal swabs; and 3) first-catch urine specimens (female and male). Results were compared to a patient infection status based on US Food and Drug Administration (FDA)-cleared assays. Results: The …

Review Of Biochemistry: Free For All, Arnulfo Mar

Open Educational Resources - Reviews

No abstract provided.

Parenting Practices And Attachment Levels In Relation To Externalizing Behaviors In Children Raised By Nonparental Caregivers, Kourtney Mia Barfield

Honors Theses

Current literature supports parenting practices and the quality of child-caregiver attachments are correlated with child externalizing behavior. However, these results typically come from samples of biological parents and their children. It is unknown if parenting practices (i.e. poor supervision, inconsistent discipline, and positive parenting) predict attachment and externalizing behavior among children of grandparents and foster parents. Previous studies have also found
that attachment mediates the relation between parenting practices and externalizing behavior among children raised by biological parents. This study aims to determine if similar relations will be found among grandchildren and foster children and if the level of attachment …

How Migratory Marine Life Connects Ecosystems From New England To Florida, Nicholas Gosling

UNH Today Archive

No abstract provided.

December 4, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Chickpea Proteome Analysis Reveals Genotype-Dependent Variations Associated With Seed Traits, Utpal Bose, Sally Buck, Xavier Sirault, Mahya Bahmani, Keren Byrne, Sally Stockwell, Sean Mcwilliam, Michelle Colgrave, Angéla Juhász, Jean Philippe Ral

Research outputs 2022 to 2026

Chickpea (Cicer arietinum L.) is the second most widely grown legume crop after soybean. Here, we measured the macronutrients and performed proteome profiling of eight chickpea cultivars using two complementary protein extraction solvents. The total protein, starch, and soluble sugar contents significantly differ between cultivars, and we quantified 2434 and 1809 proteins, respectively, from urea- and water-based extraction solvents using a data-independent acquisition approach. The proteome-level differences can vary from 9-25% for the urea-extracted proteins, and the storage protein abundances significantly differed between the cultivars, where legumin content was detected as the highest, followed by vicilin and albumin. Fifty common …

Contribution Of Fish To Food And Nutrition Security In Southern Africa: Challenges And Opportunities In Fish Production, Sahya Maulu, Confred Godfrey Musuka, Montshwari Molefe, Tlou Kevin Ngoepe, Ndakalimwe Naftal Gabriel, Joseph Mphande, Msumenji Phiri, Valdemiro Muhala, Messias Alfredo Macuiane, Mzime Regina Ndebele-Murisa, Oliver Jolezya Hasimuna, Thethela Bokhutlo, Mexford Mulumpwa, Victoria Ndinelago Erasmus, Wilson Jere, Chipo Hazel Dekesa, Chipo Plaxedes Mubaya, Manecas Francisco Baloi, Johannes Angala Iitembu, Enock Siankwilimba, Lin Zhang

School of Biological and Marine Sciences

This study investigated the role of fish in addressing food and nutrition security challenges in Southern Africa, focusing on 10 countries including Angola, Zambia, Malawi, Mozambique, Namibia, Botswana, Zimbabwe, Lesotho, Eswatini, and South Africa. It examined the current state of food and nutrition security, fish production, and fish consumption patterns. Additionally, the study investigated the challenges and opportunities to enhance fish production in these countries thereby enhancing food and nutrition security. The findings revealed persistent challenges such as a high prevalence of food insecurity and malnutrition throughout the region. Fish production is hindered by overexploitation of fishery resources, inadequate fisheries …

Wearable Technology In Intercollegiate Sport: Ethical And Legal Considerations Of Collecting Student-Athlete Biometric Data, Taryn Deshane

Honors Theses

As wearable technology becomes increasingly integrated into athletic performance tracking, questions surrounding privacy, consent, and data ownership emerge. This research investigates how universities and athletic organizations navigate the complex issues surrounding athlete biometric data (ABD) collection and usage, with a particular emphasis on intercollegiate athletics. While the use of biometric data is widespread across both professional and amateur sports, this study hones in on the college sports environment, examining how ABD is collected, the ethical concerns it raises, and how it impacts student-athletes and institutions.

This pilot study centers on student-athletes at Western Michigan University, specifically focusing on Division 1 …

Integrative Human-Mouse Gene Expression And Phylogenetics Analysis To Prioritize Genes Of Evolutionary And Biomedical Importance In The Retina And Retinal Pigment Epithelium, Edson Ishengoma, Guglielmo Roma, Shola M. Richards

Tanzania Journal of Science

Mammalian models, such as mice, are often used to study human retinal diseases, but, owing to the evolutionary time-scale separating the two species, some physiological functions involved in vision differ between the two species. Here, public RNA-seq data sets were used to interrogate genome-wide gene expression patterns in mouse and human retina and retinal pigment epithelium in order to identify genes of significance underlying visual signal processing in the two species. Individual genes with distinct and conserved expression patterns across the retinal tissues were identified both within and between species, followed by an assessment of biomedical roles in visual functions, …

Lived Experiences Of Black, Indigenous, And People Of Color (Bipoc) Helping Professionals, Shairee Lackey

Walden Dissertations and Doctoral Studies

This study was focused on the experiences of Black, Indigenous, and People of Color (BIPOC) professionals in helping professions. The goal of the research was to understand the challenges BIPOC helping professionals face due to systemic racism, burnout, compassion fatigue, and secondary traumatic stress. These factors significantly impact the well-being and effectiveness of BIPOC professionals and are often overlooked in existing literature. Grounded in critical race theory, the study used a phenomenological research design, gathering data through semistructured interviews with 13 participants. The findings revealed challenges such as microaggressions, stereotypes, discrimination, lack of representation, and cultural invalidation. Participants showed resilience …

The Challenges Of Diet Generalism In A Microbial Predator, Dictyostelium Discoideum, Shreenidhi Perukkaranai Madabhushi

Arts & Sciences Graduate Student Theses and Dissertations

Organisms vary widely in their diet breadth, ranging from specialists that feed on few resources to generalists that feed on many. Specialists have honed their ability to catch and process specific prey, but generalists must deal with prey that differ in nutritional quality and defensive mechanisms. Have generalist predators overcome costs associated with consuming multiple prey species or do they experience costly trade-offs when handling different prey? Generalist predators also live in environments that vary in the type and abundance of prey species. How do generalists navigate this variation in prey abundance and profitability and seek out their preferred prey? …