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Quantum Immortality: A Perspective If Ai Doomers Are Probably Right, Alexey Turchin, James Miller Jan 2025

Quantum Immortality: A Perspective If Ai Doomers Are Probably Right, Alexey Turchin, James Miller

Economics: Faculty Publications

What should you believe will be the likely cause of your survival if you are an AI Doomer who believes in quantum immortality? An AI Doomer believes that if their understanding of AI existential risks is correct, humanity must get extremely lucky to survive. A person who believes in quantum immortality thinks that the many-worlds interpretation of quantum physics implies that their consciousness will necessarily continue in some branch of the multiverse. This article shows that combining these two beliefs requires rejecting or going beyond simple Bayesian reasoning when estimating one's most likely cause of survival. Such estimates may have …


Natural Bone Human Education Skeletons: Investigating Restoration And Ancestry, Emelye Josko Jan 2025

Natural Bone Human Education Skeletons: Investigating Restoration And Ancestry, Emelye Josko

Annual Research Symposium

•Three real human skeletons owned by DSU were restored to a fully functional state for classroom usage, using anatomical guides and museum preservation techniques. •These skeletons have inspired the development of a new curriculum that promotes interactive learning, allowing students to engage with the skeletal remains in a hands-on environment. •Non-invasive DNA extraction methods are being employed to gather additional information about the heritage of the skeletons, enhancing the understanding of their origins and significance.


Social Behavior & Personality In Corn Snakes, Maggie-Rose Johnston Jan 2025

Social Behavior & Personality In Corn Snakes, Maggie-Rose Johnston

Theses and Dissertations (Comprehensive)

The sociality of snakes, long thought simplistic, has been shown to be governed by a host of different factors such as kinship, experience, sex, weight and personality. There is, however, still a need to untangle how snakes prioritize different kinds of information when interacting. I hypothesized that examining each dyad that composes a group could partly predict how individuals would behave in a larger group context, providing insight into the mechanisms governing aggregation. Six groups of six corn snakes (Pantherophis guttatus) had their personalities tested, then underwent dyadic interactions with each member of their cohort followed by a …


Can Fungal Endophytes Suppress Trialeurodes Vaporariorum And The Transmission Of Tomato Infectious Chlorosis And Chlorosis Viruses In Field Conditions?, Marial Makur Zechariah Paweer, Everlyne Samita Namikoye, Shem Bonuke Nchore, Komivi Senyo Akutse Jan 2025

Can Fungal Endophytes Suppress Trialeurodes Vaporariorum And The Transmission Of Tomato Infectious Chlorosis And Chlorosis Viruses In Field Conditions?, Marial Makur Zechariah Paweer, Everlyne Samita Namikoye, Shem Bonuke Nchore, Komivi Senyo Akutse

All Peer-Reviewed Publications

Field trials were conducted for two seasons in two experimental sites (Mwea in Kirinyaga and Ngoliba in Kiambu counties of Kenya) to assess the efficacy of fungal endophytes Hypocrea lixii F3ST1 and Trichoderma asperellum M2RT4 in the control of Trialeurodes vaporariorum vector of tomato infectious chlorosis virus (TICV) and tomato chlorosis virus (ToCV) through seeds inoculation. TICV and ToCV’s disease incidence, severity and the yield were also evaluated. All the fungal endophytes successfully colonized all the tomato plant parts, but the highest root colonization was observed in H. lixii F3ST1 compared to the T. asperellum M2RT4 in both seasons. The …


Nuclear Intron Sequence Variation Of The Bulinus Globosus Complex (Mollusca: Planorbidae): Implications For Molecular Systematic Analyses, Chairat Tantrawatpan, Kotchaphon Vaisusuk, Chrysantus M. Tanga, Warayutt Pilap, Naruemon Bunchom, Ross H. Andrews, Tongjit Thanchomnang, Wanchai Maleewong, Weerachai Saijuntha Jan 2025

Nuclear Intron Sequence Variation Of The Bulinus Globosus Complex (Mollusca: Planorbidae): Implications For Molecular Systematic Analyses, Chairat Tantrawatpan, Kotchaphon Vaisusuk, Chrysantus M. Tanga, Warayutt Pilap, Naruemon Bunchom, Ross H. Andrews, Tongjit Thanchomnang, Wanchai Maleewong, Weerachai Saijuntha

All Peer-Reviewed Publications

Urinary schistosomiasis is caused by the blood fluke Schistosoma haematobium, which is predominantly found in Africa. The freshwater snail Bulinus globosus is its main intermediate host. The species that make up the B. globosus group are genetically complex, and their taxonomic status remains controversial. Genetic variation, heterozygosity, and DNA recombination in B. globosus were examined using the mitochondrial cytochrome c oxidase subunit 1 (COI) and the intron 3 region of the arginine kinase gene (AkInt3). A total of 81 B. globosus snails were collected from three different localities in Kwale County, Kenya. Genomic diversity, heterozygosity, DNA recombination, and haplotype network …


Swatting Flies: Biting Insects As Non-Invasive Samplers For Mammalian Population Genomics, Anubhab Khan, Ryan Carter, Chengetai D. Mpamhanga, Daniel Masiga, Manun Channumsin, Marc Ciosi, Oliva Manangwa, Furaha Mramba, Umer Zeeshan Ijaz, Harriet Auty, Barbara K. Mable Jan 2025

Swatting Flies: Biting Insects As Non-Invasive Samplers For Mammalian Population Genomics, Anubhab Khan, Ryan Carter, Chengetai D. Mpamhanga, Daniel Masiga, Manun Channumsin, Marc Ciosi, Oliva Manangwa, Furaha Mramba, Umer Zeeshan Ijaz, Harriet Auty, Barbara K. Mable

All Peer-Reviewed Publications

Advances in next-generation sequencing have allowed the use of DNA obtained from unusual sources for wildlife studies. However, these samples have been used predominantly to sequence mitochondrial DNA for species identification while population genetics analyses have been rare. Since next-generation sequencing allows indiscriminate detection of all DNA fragments in a sample, technically it should be possible to sequence whole genomes of animals from environmental samples. Here we used a blood-feeding insect, tsetse fly, to target whole genome sequences of wild animals. Using pools of flies, we compared the ability to recover genomic data from hosts using the short-read sequencing (Illumina) …


The Impact Of Stem Self-Efficacy And Sense Of Belonging On Academic Performance For Students Of Color In Introductory Stem Courses, Danyelle Nichole Stokes Jan 2025

The Impact Of Stem Self-Efficacy And Sense Of Belonging On Academic Performance For Students Of Color In Introductory Stem Courses, Danyelle Nichole Stokes

UNF Graduate Theses and Dissertations

The study explores the interplay between STEM identity development, race and gender in relation to academic performance in STEM at the beginning of post-secondary education. Statistical analyses of this study included descriptive statistics, independent sample t-tests and a multiple linear regression. The quantitative results indicated no statistically significant differences in self-efficacy and sense of belonging scores between White students and students of color. However, participants’ open-ended responses warranted a holistic examination to look for qualitative differences in the STEM identities of students of color and White students. The findings supported existing literature on disparities in support, inclusion and access to …


Long-Term Abundance Estimates Of A Northeast Florida Estuarine Dolphin Community: Evaluating The Impacts Of The 2013–2015 Cetacean Morbillivirus Unusual Mortality Event, Allison L. Wilkins Jan 2025

Long-Term Abundance Estimates Of A Northeast Florida Estuarine Dolphin Community: Evaluating The Impacts Of The 2013–2015 Cetacean Morbillivirus Unusual Mortality Event, Allison L. Wilkins

UNF Graduate Theses and Dissertations

Tamanend's bottlenose dolphins (Tursiops erebennus) in the St. Johns River (SJR), Jacksonville, FL, are subjected to substantial anthropogenic stressors (e.g., vessel traffic, dredging, fisheries interactions) and were heavily impacted by the 2013-2015 Mid-Atlantic cetacean morbillivirus unusual mortality event (UME). High prevalence of skin lesions and frequent sightings of emaciated dolphins suggest declining health and viability of the SJR dolphin community. Sighting data from Jul. 2011 to Oct. 2019 provided the rare opportunity to investigate long-term changes in dolphin abundance surrounding the UME. This study produced the first dolphin abundance estimate within the Jacksonville Estuarine System stock since 1997, …


Comparison Of Post-Exercise Lipid Oxidation Rates Between Lower And 1 Upper-Body Resistance Training In Well-Trained Females, Alyssa L. Parten Jan 2025

Comparison Of Post-Exercise Lipid Oxidation Rates Between Lower And 1 Upper-Body Resistance Training In Well-Trained Females, Alyssa L. Parten

Dissertations

INTRODUCTION: Lipid oxidation (LOx) is a relevant physiological process linked to metabolic health. Despite growing interest in resistance training (RT) as a means to influence substrate utilization LOx responses in females remain poorly characterized, with no study examining whether lower- and upper body RT elicits different LOx patterns during the recovery period following exercise. This distinction may  be relevant because lower-body exercises involves greater fat-free mass (FFM) and energy expenditure,  whereas upper-body exercises recruit less FFM, potentially influencing metabolic effects.

PURPOSE: To  determine if LOx rates after exercise differ between lower- and upper-body RT in well-trained females.

METHODS: Twenty-two females …


Menstrual Cycle Phase Exerts No Influence On Running Economy Parameters In Recreational Female Runners, Savanna K. Knight Jan 2025

Menstrual Cycle Phase Exerts No Influence On Running Economy Parameters In Recreational Female Runners, Savanna K. Knight

Dissertations

Hormonal fluctuations that occur throughout the menstrual cycle (MC) have been shown to affect substrate utilization and oxygen uptake when running. These MC induced changes could manifest as altered running economy (RE) when expressed as energy cost (Ec) and oxygen cost (O2c). Therefore, the current study aimed to determine if RE differs between MC phases, the early follicular phase (E-FP) and the mid-luteal phase (M-LP). Twelve eumenorrheic female recreational runners (ages 25 ± 4y; VO2peak 40.9±4.6 ml/kg/min) completed submaximal RE bouts (60%, 70%, 80% of VO2peak) during the E-FP and M-LP. During each bout, oxygen consumption (VO2), respiratory exchange ratio …


Unique Challenges Of Small Special Educator Preparation Program Faculty At Hbcus, Priscilla Spencer, Rachel Juergensen Jan 2025

Unique Challenges Of Small Special Educator Preparation Program Faculty At Hbcus, Priscilla Spencer, Rachel Juergensen

Journal of Case Learning & Exceptional Learners

Evolving special educator preparation programs face distinct challenges that impact faculty and influence the quality of the programs for preservice teachers. This unique challenge case study is designed to describe the experiences of two special educator preparation faculty members serving at Historically Black Universities with small, evolving special educator preparation programs. This paper discusses challenges such as mentorship, course loads, resources, service to the community, and collaboration that these faculty members face and the methods that have been developed to moderate these challenges. This case also highlights the value of acknowledging challenges that exist in small special educator preparation programs …


From Misinformation To Policy Solutions: Teaching Herd Immunity And Vaccine Hesitancy Through Real-World Case Studies Of Measles Outbreaks, Laurieann Klockow Jan 2025

From Misinformation To Policy Solutions: Teaching Herd Immunity And Vaccine Hesitancy Through Real-World Case Studies Of Measles Outbreaks, Laurieann Klockow

Biomedical Sciences Faculty Research and Publications

Vaccine hesitancy threatens herd immunity, contributing to the resurgence of measles outbreaks. This lesson engages upper-level biomedical science students in analyzing the complex interplay between vaccination rates, herd immunity and vaccine exemption policies through examination of the 2019 New York measles outbreak that threatened the United States’ measles elimination status. Students critically evaluate anti-vaccine misinformation, analyze epidemiological data and develop evidence-based policy recommendations to increase vaccination rates. The lesson combines team-based learning with authentic assessment through vaccine policy development, moving beyond knowledge acquisition and content to building scientific literacy and evidence-based reasoning skills essential for scientifically literate citizens and future …


Modifying The Miller Test To Supplement Board Of Education V. Pico: A Novel Approach For Resolving Censorship Cases In School Libraries, Michael Lee Jan 2025

Modifying The Miller Test To Supplement Board Of Education V. Pico: A Novel Approach For Resolving Censorship Cases In School Libraries, Michael Lee

Southern Illinois University Law Journal

In recent years, the increase in book censorship laws and attempts in school libraries across the United States has led to concerns about the propriety of such censorships. This has drawn much attention to the Supreme Court’s decision in Board of Education v. Pico, which established the standard for evaluating the constitutionality of removing books from school libraries. Yet, by analyzing, under the Pico standard, the constitutionality of Texas, Florida, and Illinois’s laws pertaining to book censorship, this Note demonstrates that the Pico standard is practically limited and difficult to apply. Therefore, a more applicable test for analyzing the …


Design Thinking For Health Environments: Case Study Research On Innovation, Design Leadership, And Healthcare Complexity, Diana S. Nicholas Jan 2025

Design Thinking For Health Environments: Case Study Research On Innovation, Design Leadership, And Healthcare Complexity, Diana S. Nicholas

Antioch University Dissertations & Theses

As healthcare costs are skyrocketing, of the 6,093 hospitals in America, 53% will lose money in the current year (Coleman-Lochner, 2022). Design health innovation centers (DHICs) are formed in Europe and the United States to create efficiencies in healthcare related to budget challenges. DHICs exist in unique contexts both in America and Europe that are not yet well understood. These efforts are difficult to lead due to the lack of understanding of their worth and how their process is valuable to healthcare settings (Bhattacharyya et al., 2022). The specific problem examined here is that little is known about how DHIC …


Distal Effects Of Teenage Pregnancy And Childbirth, Amy M. Sutherland Jan 2025

Distal Effects Of Teenage Pregnancy And Childbirth, Amy M. Sutherland

Antioch University Dissertations & Theses

While pregnancy during adolescence is declining, research on the topic continues, particularly regarding: the reasons teenagers become pregnant and choose parenthood; their experiences as teen parents; and near-term outcomes for themselves and their children. The focus of this dissertation has received little study: how the experience of having been a birthing parent in adolescence continues to affect the personal experiences of individuals in midlife, if it does at all. Eight individuals between the ages of 30 and 43 who gave birth as teens were interviewed, and interpretative phenomenological analysis (IPA) was used to identify how they interpreted and made meaning …


Professional Development Needs In Educational Support For The Waldorf Teacher, Leah M. Mrozinski Jan 2025

Professional Development Needs In Educational Support For The Waldorf Teacher, Leah M. Mrozinski

Antioch University Dissertations & Theses

In the past few years of immersion into the Waldorf world through both my work and my educational pursuits, I have recognized that there is an absence of basic special education knowledge in the practice of Waldorf education. My research sought to answer the question: What topics of educational support are most relevant and needed for Waldorf teachers and trainees today? My literature review explored best practices in special education and Waldorf education and connections with polyvagal theory. More specifically, it includes a basic review of special education law, best practices in special education, how a Waldorf education meets the …


Heart-Thinking Leadership: A Transformative Approach To Binary Hierarchies In Waldorf Schools, Chiaki Uchiyama Jan 2025

Heart-Thinking Leadership: A Transformative Approach To Binary Hierarchies In Waldorf Schools, Chiaki Uchiyama

Antioch University Dissertations & Theses

This study explores heart-thinking leadership as a transformative approach to dismantling elitism, hierarchy, and binary structures in education, leadership, and diversity, equity, and inclusion (DEI). Grounded in insights from Damásio, Spinoza, Emerson, Hegelian dialectics, and wisdom traditions such as Manichaeism, African spirituality, and Indigenous feminism, it examines how third space thinking fosters inclusivity and dynamic leadership. By integrating intuition, intellect, and relational awareness, heart-thinking leadership moves beyond rigid dualisms—mind and body, self and other, power and subjugation—to cultivate a holistic way of knowing. This perspective critiques conventional DEI models that reinforce binaries of oppressor and oppressed, advocating instead for an …


Experiences Of Dissertating Students: What Works?, Laura Durkin Jan 2025

Experiences Of Dissertating Students: What Works?, Laura Durkin

Antioch University Dissertations & Theses

This study explores the experiences of doctoral graduates from Council for Accreditation of Counseling and Related Educational Programs (CACREP)-accredited Counselor Education and Supervision (CES) programs. Guided by theoretical frameworks on student attrition and institutional racism, the research investigates three primary questions: (1) What dissertation- specific programmatic factors influence time to completion for CES doctoral students? (2) What interventions most strongly promote a sense of social integration and belonging? and (3) What interventions most strongly promote academic integration and confidence in students’ ability to succeed? Data were collected anonymously through an online survey, which included demographic and open-ended questions. Twelve participants …


Empowering Futures Together: The Role Of Emotional Intelligence In Postsecondary Outcomes For Young Adults With Autism, Olivia Bliss Jan 2025

Empowering Futures Together: The Role Of Emotional Intelligence In Postsecondary Outcomes For Young Adults With Autism, Olivia Bliss

Antioch University Dissertations & Theses

Autistic young adults are disproportionately excluded from postsecondary education and employment opportunities, with significantly lower rates of college completion and higher levels of unemployment than their non-disabled peers. While social and emotional learning (SEL) has been widely promoted as a vehicle for student success, research on how emotional intelligence (EQ) shapes the postsecondary experiences of neurodivergent individuals remains limited. This explanatory sequential mixed methods study explores how emotional intelligence competencies influence postsecondary outcomes and satisfaction among autistic young adults. Participants completed the Six Seconds Emotional Intelligence Assessment (SEI), and their results were analyzed alongside demographic and outcome data. The second …


Ethical Imperatives For Rational Paternalism In Advisor-Client Relationships, Igor A. Zey Jan 2025

Ethical Imperatives For Rational Paternalism In Advisor-Client Relationships, Igor A. Zey

Antioch University Dissertations & Theses

This study seeks to understand the role of ethics and rational paternalism in the practice of financial advising. A significant amount of research examines the effects of rational paternalism on the governmental and institutional levels. Very little research has addressed the issues associated with rational paternalistic behavior by advisors toward their clients. Investopedia (2013) focuses on advisors’ ethics and moral responsibilities, underscoring the ethical standards clients should expect from their financial advisors. However, practically none of the literature examines the ethics, morals, and practical aspects of individual paternalism. In response, this study examines the concept of rational paternalism in advisor-client …


Childhood Aggression: A New Conceptualization, Hannah G. Harrison Jan 2025

Childhood Aggression: A New Conceptualization, Hannah G. Harrison

Antioch University Dissertations & Theses

Childhood aggression is a frequently observed behavioral phenomenon, yet lacks a precise
definition in both the DSM-5-TR and current research literature. Definitional ambiguity and
construct enmeshment continue to create construct confusion for researchers, clinicians, and
informants. This empirical review of the current literature and diagnostic criteria examines how
childhood aggression has been historically conceptualized, defined, and described. The primary
aim was to identify and clarify inconsistencies in current definitions and to address knowledge
gaps to improve diagnostic clarity. Through a thematic synthesis of recent literature, several key
issues emerged: the absence of a precise definition of childhood aggression; reliance on …


Mapping Kirtland’S Warbler (Setophaga Kirtlandii) Stationary Non-Breeding Habitat: Characterizing Land Cover Within The South-Central Bahamas And Evaluating The Impacts Of Sea Level Rise, Cole Anthony Scrivner Jan 2025

Mapping Kirtland’S Warbler (Setophaga Kirtlandii) Stationary Non-Breeding Habitat: Characterizing Land Cover Within The South-Central Bahamas And Evaluating The Impacts Of Sea Level Rise, Cole Anthony Scrivner

Antioch University Dissertations & Theses

Understanding the spatial distribution of current and future habitat for the Kirtland’s Warbler (Setophaga kirtlandii) and other threatened species is critical for guiding conservation planning in The Bahamas. Our study mapped land cover and impacts of sea level rise across the south-central Bahamian islands, as an initial step to determine suitable areas for Kirtland’s Warblers in the region. We used a Random Forest (RF) classification of multispectral satellite image bands and indices from Landsat and Sentinel-2 image composites to predict land cover. The classification identified tropical dry forest communities (broadleaved, semi-evergreen trees and shrubs known as coppice) as …


Embracing The Suck: Overcoming Moral Injury-Related Attachment Trauma Through Outdoor Adventure, Emerald D. Ralston Jan 2025

Embracing The Suck: Overcoming Moral Injury-Related Attachment Trauma Through Outdoor Adventure, Emerald D. Ralston

Antioch University Dissertations & Theses

Moral injury is increasingly recognized as a distinct and debilitating consequence of military service, arising when individuals engage in, witness, or are unable to prevent actions that transgress their deeply held moral beliefs. In this dissertation, I argue that this form of trauma can be experienced as an attachment rupture, particularly when the military—functioning as an institutional attachment figure—betrays the servicemember’s trust. Such experiences compromise internal working models (IWMs) of self, others, and the world, and may result in complex trauma symptoms, including dissociation, depersonalization, and profound relational disconnection. These injuries are frequently stored in the body, rendering traditional cognitive …


University Of Richmond Magazine - Summer 2025 Jan 2025

University Of Richmond Magazine - Summer 2025

University of Richmond Magazine

The University of Richmond's Alumni Magazine was first published as The Alumni Bulletin in 1936 and continues to this day as the University of Richmond Magazine.


University Of Richmond Magazine - Autumn 2025 Jan 2025

University Of Richmond Magazine - Autumn 2025

University of Richmond Magazine

No abstract provided.


Stigma Of Obesity And Healthcare Utilization, Moya A. O'Leary Jan 2025

Stigma Of Obesity And Healthcare Utilization, Moya A. O'Leary

Antioch University Dissertations & Theses

The impact of personal factors on healthcare utilization is an essential area of research to improve overall health outcomes among the population. This study explored the relationship between perceived stigma and healthcare avoidance among men and evaluated the relationship between self-reported body mass index (BMI) and avoidance of healthcare appointments due to weight-related stigma and other reasons. This study found no significant relationship between BMI and avoidance of preventive medical appointments due to perceived stigma. However, men from all weight categories endorsed avoiding preventive healthcare appointments due to weight-related reasons and for other reasons. This study explored the reported reasons …


The Lived Experiences Of Trauma In Autistic Adults: A Thematic Analysis, Briana Trageser Jan 2025

The Lived Experiences Of Trauma In Autistic Adults: A Thematic Analysis, Briana Trageser

Antioch University Dissertations & Theses

A qualitative research study focused on Autistic adults explored the lived experiences of trauma. Participants included Autistic adults who have either been professionally diagnosed with Autism Spectrum Disorder or who self-identify as Autistic. Data was collected through a survey with 12 open-ended questions. A thematic analysis revealed six themes: (a) adverse childhood experiences, (b) exposure to violence and loss, (c) difficulty relating to others, (d) complex mind and sensory experiences, (e) medical and mental health challenges, and (f) autistic identity. The themes revealed instances of Autistic people experiencing trauma in ways that differ and vary in clinical presentation from their …


Working With Physical And Virtual Manipulatives: A Systematic Review Of Affordance And Cognitive Engagement Manifested Through Implementation, Seokmin Kang, Chun-Hao Chang, Sungyeun Kim Jan 2025

Working With Physical And Virtual Manipulatives: A Systematic Review Of Affordance And Cognitive Engagement Manifested Through Implementation, Seokmin Kang, Chun-Hao Chang, Sungyeun Kim

Teaching and Learning Faculty Publications

Virtual tools are rapidly supplementing physical tools in classrooms. Although extensive research has compared the benefits of using virtual and physical manipulatives, few studies have systematically explored the learning benefits of using a physical and a virtual tool. As the major learning goal in science, technology, engineering, and mathematics (STEM) education is to help students better understand scientific and mathematical concepts and processes, this study reviewed empirical studies comparing learning performance between working with physical and virtual manipulatives published between 2000 and 2022 in Education and Psychology journals. The results revealed inconsistent patterns in learning comparison across studies even with …


Multi-Risk Governance Of Solar Radiation Modification, Jonathan B. Wiener, Tyler Felgenhauer, Mark E. Borsuk Jan 2025

Multi-Risk Governance Of Solar Radiation Modification, Jonathan B. Wiener, Tyler Felgenhauer, Mark E. Borsuk

Faculty Scholarship

Solar radiation modification (SRM) presents important challenges to risk regulation and governance, arising from the array of multiple risks that SRM may influence. SRM would not simply reverse climate change, but could pose further ancillary impacts, depending on the method of SRM, such as stratospheric aerosol injection (SAI), marine cloud brightening (MCB), or a space-based planetary sunshade system (PSS). We identify multiple risks that SRM may influence, both biophysical and sociopolitical, to be compared to the multiple risks that may be affected by greenhouse gas (GHG) mitigation and climate adaptation. This multi-risk framework helps analysts and decision makers identify, evaluate, …


Recent Changes In Discretionary Denials Of Drug Patent Challenges, S. Sean Tu, Arti K. Rai, Aaron S. Kesselheim Jan 2025

Recent Changes In Discretionary Denials Of Drug Patent Challenges, S. Sean Tu, Arti K. Rai, Aaron S. Kesselheim

Faculty Scholarship

Recent policy shifts at the U.S. Patent and Trademark Office (USPTO) have sharply limited the use of two administrative pathways for patent reviews, inter partes review (IPR) and post-grant review (PGR). Congress created these administrative pathways to provide a faster and less costly way to challenge weak patents. Recently, the USPTO has expanded the use of “discretionary denials,” invoking a new “settled expectations” rationale that blocks IPR petitions for patents more than about six years old. From May to September 2025, 60% of 506 requests for discretionary denial were granted, triple historical levels, including one-third involving drug patents. These changes …