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Holos, María Álvarez Espada

Grado en Diseño de Interiores

El proyecto deberá resolver la articulación de un programa habitacional y de taller o despacho de un profesional a elección del alumno, con la sensibilidad de encontrarse en un edificio emblemático del racionalismo madrileño. Para precisar los objetivos de la transformación interior los alumnos podrán asociar a un personaje en concreto la interpretación a realizar.

Se deberán tomar como referencias de partida las características materiales y de diseño propias de los interiores de aquel periodo, actualizadas a los parámetros de confort contemporáneos y operando, en las modificaciones espaciales interiores, definiendo la organización interior, sus acabados, su iluminación y su mobiliario. …

Evaluation The Level Of Interleukin-6 And Interleukin-10 In Patients With Acute Myeloid Leukemia, Hiba Aldeen, Muna Abdulbasit Kashmoola

Iraqi Postgraduate Medical Journal

BACKGROUND: Acute Myeloid Leukemia (AML) is a hematopoietic stem cell disease. IL-6 and IL-10 play critical roles in AML pathogenesis; IL-6 regulates hematopoiesis and leukemic blast formation, and IL-10 inhibits pro-inflammatory responses in leukemic cells.OBJECTIVE: To evaluate IL-6 and IL-10 levels in AML patients and assess their correlation with clinical and laboratory parameters.METHOD: A case-control study, conducted in Nineveh Province from January to October 2024, included 30 newly diagnosed AML patients and 30 healthy controls. Hematological and biochemical tests, including Complete Blood Count, bone marrow aspirate, flow cytometry, and serum IL-6 and IL-10 levels (measured by ELISA), performed at diagnosis …

Capacity Building In The Irish Brewing And Distilling Sector For Raw Materials Utilisation, By-Products Management, And Environmental Impact Assessment, Ekene C. Umego

Doctoral

The Irish brewing and distilling sector has shown a consistent increase in number, production output, sales, and export value in the last decade. This has implications for raw materials requirements, assessment, and by-products management for the sustainability of the sector. As a result, the main aim of this research study was to evaluate the status of raw materials use and assessment within the Irish brewing and distilling sector, explore by-products management options and valorisation initiatives, and analyse the environmental impact of Irish whiskey production. The first approach was a survey study to collect data on major raw material inputs use …

Exploring Pre-Kindergarten Teachers' Experiences With Engaging Black Boys In Literacy Instruction, Airreia Faith Pierce

Walden Dissertations and Doctoral Studies

Recent studies convey the critical need for teachers to use culturally relevant pedagogy (CRP) to engage Black boys in literacy instruction. The problem was that in the Sunshine School District (SSD: a pseudonym), pre-kindergarten (pre-K) teachers found it challenging to engage Black boys in literacy instruction. Framed by Ladson-Billings’s CRP, the purpose of this basic qualitative study was to explore how pre-K teachers engaged Black boys in literacy instruction and how teachers’ instructional practices aligned with CRP. To collect data, a purposeful sample of 11 pre-K teachers from SSD participated in semistructured interviews. Thematic analysis, using open coding, was applied …

Up Los Baños Journal, Volume 23 - Regular Issue

U.P. Los Baños Journal

UP Los Baños Journal, Volume 23 - Regular Issue

Maternal Nutriture And Concurrent Wasting And Stunting Among Under-Five Children: A Systematic Review, Aileen R. De Juras, Rodesa N. Forcadilla, Mary Ann M. Ingua, Angeline A. Bueno

Journal Article

Concurrent wasting and stunting (WaSt) is a severe form of child undernutrition associated with increased morbidity and mortality. While maternal nutritional status independently influences wasting and stunting, its role in their co-occurrence among children remains insufficiently explored. This systematic review aimed to examine associations between WaSt and maternal nutritional status and related determinants, as well how WaSt is defined, measured, and reported. It was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and registered with PROSPERO International Prospective Register of Systematic Reviews (CRD42024493969). Structured searches in Scopus, Web of Science, and Cochrane databases were …

Initial Growth Of Inclusive Knowledge And Leadership Practices By Science Education Teacher-Leaders, Elizabeth B. Lewis, Elizabeth Hasseler, Rachel Benzoni, Gina S. Matkin, Wendy Smith, Daniel R. Claes, David M. Harwood, L. J. Mcelravy, Dawn Jaramillo

Department of Teaching, Learning, and Teacher Education: Presentations

Slies of a presentation given at the 2025 Annual International National Association for Research in Science Teaching (NARST) Conference on the initial results from an iterative program design for educating science education leaders.

Cover Crops Can Reduce Greenhouse Gas Emissions From No-Till Maize In Southern Brazil: Insights From A Long-Term Field Experiment, Guilherme Rosa Da Silva, Adam J. Liska, Cimélio Bayer

Adam Liska Papers

Brazil is one of the countries that has the most agricultural area under no-till (NT) management. This research study aims to evaluate life-cycle greenhouse gas (GHG) emissions from maize (M) grain production in agroecosystems that used different cover crops under NT management in southern Brazil. The data for this study were from a long-term 41-year field experiment in southern Brazil. The long-term experiment evaluated the effects of fallow (F) and cover crops (oat (O), vetch (V), cowpea (B), pigeon pea (P), and lablab (L)) on nitrous oxide and methane emissions and soil carbon (C) sequestration in maize agroecosystems. Five cropping …

Inactivation Of Zika Virus With Hydroxypropyl-Beta-Cyclodextrin, Cory R. Hewitt, Nicholas J. Wixon, Arthur Gallegos, You Zhou, Victor C. Huber, M. Scott. Killian

Nebraska Center for Biotechnology: Faculty and Staff Publications

Background/Objectives: Zika virus (ZIKV) infection is associated with life-threatening diseases in humans. To date, there are no available FDA-approved therapies or vaccines for the specific treatment or prevention of ZIKV infection. Variation in the ZIKV envelope protein (Env), along with its complex quaternary structure, presents challenges to synthetic approaches for developing an effective vaccine and broadly neutralizing antibodies (bnAbs). We hypothesized that beta-cyclodextrin (BCD) could be used to uniquely inactivate infectious ZIKV without disruption of Env.

Methods: ZIKV was propagated in Vero cells and admixed with BCD. The BCD-treated ZIKV was evaluated for infectivity using immunofluorescence and quantitative …

Archaeoparasitology Of The Colorado Plateau, Karl J. Reinhard, Morgana Caacho

Karl Reinhard Publications

Archaeoparasitology has been conducted in the Southwest for 57 years. In the first decade of the period, two pictures of parasitism emerged. Analysis of compressed organic sediments from a latrine at Elden Pueblo presented a spectrum of geohelminths not different from medieval Europe. These findings contrast pronouncedly with an analysis of coprolites from all other studies that show consistent pinworm parasitism at other sites in the Southwest. We summarize the paleoepidemiological bases for these contrasting phenomena.

Skin Color Cannot Be Confined To Six Categories: Comparing The Fitzpatrick Scale And Colorimetric Measures, Henry Lim, Kristina Kafle, Reem Ayoub, Dana Olsen, Ysabelle Martinez, Rafael Do Valle, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen E. Weis

North Texas Research Forum 2025

Purpose The Fitzpatrick Scale (FS), originally developed to dose photochemotherapy in Caucasian skin, has become widely adopted for skin color categorization. It originally included types I-IV, with types V-VI added later for darker skin. The FS was designed for UV radiation reactivity assessment. However, it is increasingly used as a proxy for objective skin color classification, despite being based on a subjective questionnaire. Individual Typology Angle (ITA), a validated colorimetric measurement, presents a potential alternative. Previous studies examining these classification systems have been limited by small sample sizes and uneven distribution across skin tones with subjects predominantly having lighter skin …

Development And Validation Of An Accurate And Precise Skin Color Scale, Henry Lim, Christina Guo, Reem Ayoub, Rafael Do Valle, Kristina Kafle, Ysabelle Martinez, Dana Olsen, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis

North Texas Research Forum 2025

Introduction: Utilization of the Fitzpatrick scale to describe skin color does not adequately account for variations in pigmentation that are reflective of skin color characteristics of persons from diverse racial and ethnic backgrounds. This study aims to create a better way to describe skin color. Methods: We developed an 11-point color scale. This Skin Color Scale (SCS) was reproduced onto a physical card that could be placed onto a research participant’s inner arms for independent scale interpretation. Participants and two investigators selected the best matching scale interpretation value for each arm. Self-acquired and investigator assessed Fitzpatrick scores were taken. These …

Filipinx Americans In U.S. Higher Education: A Mixed-Methods Critical Study Of Student Engagement Using The Culturally Engaging Campus Environments Model, Gerald Ariston Doton Corporal

Educational and Organizational Learning and Leadership Dissertations

Who are Filipinx American college students and what are their experiences in U.S. higher education? The academic literature emphasizes the importance of disaggregating empirical data on sub-populations within the Asian American and Pacific Islander racial diaspora to fully understand their experiences in a variety of contexts (Teranishi et al., 2015). In higher education administration, there is limited empirical data on Asian American and Pacific Islander college students and it is further limited when examining specific racial subgroups, such as Filipinx Americans (Museus & Maramba, 2011). This has implications for administrators in U.S. postsecondary institutions, particularly regarding their capacity to appropriately …

Fishing For Empathy: Fishbowls And Neurorhetorics For Mitigating Bias, Prejudice, And Hate In Human Relations, Shalina Jasmine Akins, Steven Ray Krivanek

Educational and Organizational Learning and Leadership Dissertations

This study explored bias, prejudice, and hate from anthropological, neurobiological, and social-cognitive psychological lenses to better understand dehumanization of the “other.” The concept of neurorhetorics was introduced as a framework for understanding and mitigating our natural propensity to disparage and ridicule that which is not us. Neurorhetorics was explored as a means to mitigate bias, build bridges, and promote empathy and understanding across any and all differences. The Fishbowl model of communication was used as an intervention framework and this study examined its efficacy as an alternative to traditional rhetorical methods of discourse such as interviews, debates, and focus groups …

Exploring Leadership Capabilities Developed As A Mother: Toward A New Theory Of Mother-Leader Intuitionship, Melinda Abel Ursino, Laura Marie Rivera

Educational and Organizational Learning and Leadership Dissertations

Your perspective as a Mom changes the way you lead in every aspect.

— Liuba Grechen Shirley, VoteMama Founder

Throughout the history of the United States, there has never been such a substantial rise in the number of Mothers in the paid workforce as in the last 3 decades. Yet, despite this growth they remain underrepresented in leadership positions. This underscores why we, as both researchers and Mothers, believe it is critical to apply a Mother's lens to conversations about workplace leadership. Our research begins by examining contemporary leadership theories, focusing on parallels between Motherhood and four of the popular …

"Baby-Steps For Baby Business": Diverse Market, Challenges, And Workable International Regulation For Cross-Border Commercial Surrogacy, Ellene Ko

Cardozo International & Comparative Law Review

The note examines the rapid growth of transnational commercial surrogacy as a multibillion-dollar industry, driven by assisted reproductive technologies and fertility tourism. It highlights the legal conflicts and challenges arising from the patchwork of international surrogacy regulations, including issues of citizenship, exploitation, and enforcement of cross-border contracts. The analysis advocates for an international convention to establish a clear legal framework for transnational surrogacy, emphasizing the need for shared responsibility between global and national oversight bodies to prevent exploitation and ensure ethical practices.

A Hybrid Cloud Data Lake Architecture Supporting The Integration Of Clinical And Genomics Data, Apollo Mcowiti, Heidi Dowst, Fei Zheng, Susan Hilsenbeck, Christopher Amos

Center for Medical Ethics and Health Policy Staff Publications

Objective: Cancer centers must quickly integrate clinical genomics data from different vendors for oncology operations and research. Clinical data warehouse architectures are costly to construct and brittle, and they are not readily amenable to the rapid changes in oncology research. We introduce a cost-effective hybrid cloud Data Lake architecture for storing clinical genomic data from different vendors, aiding both clinical and research workflows.

Methods: We created a Data Lake architecture based on the zone architecture, with four layers: ingestion, storage, transformation, and interaction. The layers are implemented with a hybrid cloud architecture. Rich metadata created from patient and genomic data …

The Demodex Expert Panel On Treatment And Eyelid Health (Depth) Consensus Regarding The Preferred Treatment For Demodex Blepharitis, Eric Donnenfeld, Kelly K Nichols, Brandon D Ayres, Marjan Farid, Preeya K Gupta, Richard Lyndon Lindstrom, Stephen Pflugfelder, Christopher E Starr, Nandini Venkateswaran, Ian Benjamin Gaddie, Paul M Karpecki, Cecelia Koetting, Selina Mcgee, Laura M Periman, Elizabeth Yeu

Faculty, Staff and Students Publications

Purpose: To reach consensus on Demodex blepharitis (DB) treatment approaches using a modified Delphi process involving 15 ocular surface disease experts.

Methods: The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) consisted of 15 well-published ocular surface disease experts. Panelists completed two online surveys, a live consensus meeting, and a follow-up survey. The surveys consisted of scaled and multiple-choice questions related to the clinical and patient-reported outcomes of DB and its treatment. For the scaled questions using a 1 to 9 Likert scale, consensus was defined as weighted mean scores of 1-3 and 7-9, whereas for multiple-choice questions, consensus …

Using Fungal Dna Barcoding To Identify Fungal Species In A James River Park System Soil Microbiome, Erwin Murray, D Jennings

Undergraduate Research Posters

Fungi in the soil have the ability to form mutualistic relationships with plant roots and improve the way they resist a variety of plant diseases and abiotic stressors, influencing the survivability of the plants. The James River Park System (JRPS) is home to a variety of ecosystems that support diverse plant and fungal populations, including native plants and invasive plants. Therefore, it is important to identify what is present in the soil microbiome. The purpose of this project is to isolate fungal sequences from soil samples collected in the JRPS to identify what fungal species are present in the JRPS …

Two-Dimensional Speckle Tracking Of The Ascending Aorta: A Novel Approach To Evaluate Arterial Stiffness In Pediatric Patients With Repaired Conotruncal Anomalies Using Echocardiography, Anmol Goyal, Anitha Parthiban, David A White, Daniel Forsha, Doaa Aly

Faculty, Staff and Students Publications

Background: Children with repaired conotruncal abnormalities (CTA) are at risk of progressive aortic dilation and deteriorating aortic elasticity even after surgical correction. Strain imaging, using a 2-dimensional speckle tracking echocardiography (2D-STE), has been used for arterial stiffness assessment, but pediatric data are still lacking. We investigated the feasibility, reproducibility, and clinical value of 2D-STE derived ascending aorta (AAo) stiffness in children with repaired CTA.

Methods: 22 pediatric patients with repaired CTA were included along with 25 age- and sex- matched healthy controls (mean age 10.2 ± 4.5 years). Conventional 2D echocardiographic and 2D-STE assessment of AAo mechanics was performed. M-mode …

Initiating Insulin Pumps In Youth With New-Onset Type 1 Diabetes: A Quality Improvement Initiative, Mili Vakharia, Sarah K Lyons, Don Buckingham, Mark Rittenhouse, Siripoom Mckay, Rona Sonabend, Grace Kim

Faculty, Staff and Students Publications

Introduction: Insulin pump therapy is recommended for youth with type 1 diabetes (T1D) as it enhances quality of life and improves glycemic management. We led a quality improvement initiative to increase insulin pump use in youth younger than 18 years of age with recently diagnosed T1D (duration < 1 y) from a baseline of 17% to 27% from January 2021 to December 2023. As a balancing measure, we evaluated the diabetes-related ketoacidosis (DKA) rate in the same cohort as nonpump users.

Methods: We implemented the following plan-do-study-act cycles: (1) development and implementation of pump initiation algorithm, including minimal safe start criteria and education on ketosis management with pump action plan, (2) establishing clinic follow-up within 90 days of pump start, (3) expansion of the pump algorithm at additional clinic locations, (4) early patient/caregiver education …

Prospective Multicenter Longitudinal Measurement Of Liver Stiffness In School-Age Children With Cholestatic Liver Disease, Benjamin L Shneider, Nathan P Goodrich, Wen Ye, Jean P Molleston, Daniel H Leung, Ronald J Sokol, Laurel Cavallo, Kasper Wang, Pamela L Valentino, Jeffery H Teckman, James E Squires, Shikha S Sundaram, Philip Rosenthal, Rene Romero, Alexander G Miethke, Kathleen M Loomes, Rohit Kohli, Saul J Karpen, Binita M Kamath, M Kyle Jensen, Jorge A Bezerra, Lee M Bass, John C Magee, Children

Faculty, Staff and Students Publications

Background and aims: A multicenter prospective longitudinal study of vibration-controlled transient elastography (VCTE) in school-age children with biliary atresia (BA), alpha-1 antitrypsin deficiency (a1-AT) and Alagille syndrome (ALGS) was undertaken to test the hypothesis that there would be measurable disease progression over 2 years.

Methods: Vibration-controlled transient elastography was performed annually for 2 years in children with BA, a1-AT and ALGS.

Results: Valid liver stiffness measurement (LSM) was determined at baseline/second follow-up in 254/180 (71%), 104/58 (56%) and 100/61 (61%) participants (mean elapsed time 2.27 years) with BA, a1-AT and ALGS, respectively. Modeling did not reveal a relationship between LSM …

Risk Scores For Choledocholithiasis Perform Poorly In Patients With Hemolytic Diseases: A Pedi Database Report, Jennifer Thompson, Wenly Ruan, Douglas S Fishman, Matthew Giefer, Kyung Mo Kim, Mercedes Martinez, Luigi Dall'oglio, Valerio Balassone, Filippo Torroni, Paola De Angelis, Simona Faraci, Cynthia Tsai, Michael Wilsey, Racha Khalaf, Petar Mamula, Quin Liu, Yuhua Zheng, Bradley A Barth, David Michael Troendle

Faculty, Staff and Students Publications

Patients with hemolytic diseases are at increased risk for gallstone-related complications. Modified scoring systems have been developed to assess which pediatric patients would benefit from endoscopic retrograde cholangiopancreatography (ERCP) to treat choledocholithiasis. This study aimed to evaluate the ability of the available criteria to determine which pediatric patients with hemolytic diseases are likely to benefit from ERCP. A secondary analysis was performed using the Pediatric ERCP Database Initiative database, which contains prospectively collected data from 1,124 ERCPs at tertiary-care institutions. We compared patients with a hemolytic disease to those without. Data was analyzed by two-tailed Fisher’s exact test and paired …

Comment On “Effectiveness And Safety Of Oral Vancomycin For The Treatment Of Inflammatory Bowel Disease Associated With Primary Sclerosing Cholangitis: A Systematic Review And Pooled Analysis”, Richard Kellermayer, Peter Lewindon, Cynthia Buness, James Tabibian, Kevin Johnson, Shamita Shah, Parambir Dulai, Ahmad H Ali, Ayesha Shah, Gerald Holtmann, Harland S Winter

Faculty, Staff and Students Publications

No abstract provided.

Interval Advanced Adenomas And Neoplasia In Patients With Negative Colonoscopy Following Positive Stool-Based Colorectal Cancer Screening Test, Kyle S Liu, Rollin George, Caleb Shin, Jia Q Xiong, Taher Jamali, Yan Liu, Priya Roy, Sonia Singh, Samuel Ma, Hashem B El-Serag, Mimi C Tan

Faculty, Staff and Students Publications

BACKGROUND/AIMS: Fecal occult blood test (FOBT) and fecal immunohistochemical test (FIT) are used for colorectal cancer (CRC) screening. However, when no adenomas are found following a positive FOBT/FIT, the future risk of advanced adenomas or colorectal cancer (CRC) is unclear. We determined the incidence and determinants of advanced adenomas or CRC after a negative index colonoscopy following a positive FOBT/FIT.

METHODS: We identified patients in the Harris Health System (Houston, Texas) who underwent a colonoscopy following a positive FOBT/FIT from 01/2010 to 01/2013. We compared the incidence rates of advanced adenomas (≥ 1 cm, villous histopathology, or high-grade dysplasia) or …

Resilience Of The Gut Microbiome To Short Proton Pump Inhibitor Therapy With Or Without High-Dosage L Reuteri In H Pylori-Infected Adults, Stefano Bibbò, Gustav Ahlström, Giovanni Mario Pes, David Y Graham, Lars Engstrand, Elettra Merola, Maria Pina Dore

Faculty, Staff and Students Publications

Background: Helicobacter pylori eradication therapy typically consists of a combination of antibiotics and an antisecretory drug. Probiotics may be added to reduce side effects and possibly improve outcomes.

Materials and methods: We conducted a double-blind, randomized trial of pantoprazole plus either Lactobacillus reuteri (Gastrus) (high dose) or a matching placebo to assess the impact on the gut microbiota of H. pylori-positive adults. Fecal samples were collected at baseline and after one and 2 months for shotgun metagenomic sequencing.

Results: A total of 26 patients were recruited and completed therapy. L. reuteri was only detected in the group that received supplemental …

Recessive Loss-Of-Function Variants In Dph1 Identified As The Molecular Cause In A Sibling Pair Previously Diagnosed With Fine-Lubinsky Syndrome, Emily R Waskow, Lisa T Emrick, Jill A Rosenfeld, Shamika Ketkar, Lindsay C Burrage, Daryl A Scott

Faculty, Staff and Students Publications

Fine-Lubinsky syndrome is a rare clinically defined syndrome sometimes referred to as brachycephaly, deafness, cataract, microstomia, and impaired intellectual development syndrome. Here we provide a clinical and molecular update for a sibling pair diagnosed with Fine-Lubinsky syndrome. An extensive genetic work-up, including chromosomal microarray analysis and quad exome sequencing, was nondiagnostic. However, a research reanalysis of their exome sequencing data revealed that both were homozygous for an intronic c.749+39G>A [NM_001383.6] variant in DPH1. RNAseq analysis performed on RNA from fibroblasts revealed significantly reduced expression of DPH1 transcripts suggestive of abnormal splicing followed by nonsense mediated mRNA decay. Since the …

Id-Gba: Subgraph Extension With Information Distance Guilt By Association In Complex Networks, Predrag Obradovic, Vladimir Kovacevic, Aleksandar Milosavljevic, Varduhi Petrosyan

Faculty, Staff and Students Publications

Here, we introduce the ID-GBA (Information Distance Guilt By Association) method to expand highly connected sets of nodes by deploying a novel algorithm for subgraph extension based on the guilt-by-association principle and information distance. In this study, ID-GBA was utilized to expand disease clusters, and identify novel disease genes. We first validate its ability to expand related disease sets from disease/disease graphs built using Open Targets' gene association scores. We then analyze disease/control gene expression networks and show that ID-GBA recaptures known disease genes in nine disease/control graphs. Compared to existing methods such as Random Walk with Restarts and Personalized …

A Natural Small Molecule Isoginkgetin Alleviates Hypercholesterolemia And Atherosclerosis By Targeting Acly, Zhidan Zhang, Meijie Chen, Yitong Xu, Zhihua Wang, Zhenghong Liu, Chenyang He, Fanshun Zhang, Xiaojun Feng, Xiayun Ni, Yuanli Chen, Jixia Wang, Xinmiao Liang, Zhifu Xie, Jingya Li, Maciej Banach, Jaroslav Pelisek, Yuqing Huo, Yunhui Hu, Paul C Evans, Li Wang, Xiao-Yu Tian, Jianbo Xiao, Yuhua Shang, Yijun Zheng, Xunde Xian, Jianping Weng, Suowen Xu

Faculty, Staff and Students Publications

Rationale: Atherosclerotic cardiovascular disease (ASCVD) represents the predominant cause of mortality and morbidity globally. Given the established role of hypercholesterolemia as a significant risk factor for ASCVD, the discovery of new lipid-lowering medications is of paramount importance. ATP citrate lyase (ACLY) is a crucial enzyme in cellular metabolism, providing acetyl-CoA as the building block for the biosynthesis of fatty acids and cholesterol. Consequently, it has emerged as a promising drug target for innovative treatments of lipid metabolic disorders.

Methods: Virtual screening of a natural product library was performed to identify small-molecule ACLY inhibitors, leading to the discovery of isoginkgetin (ISOGK). …

Diagnostic Delay In Type I Autoimmune Pancreatitis: Clinical, Imaging, Endoscopic And Histologic Predictors Of Timely Diagnosis, Andres Urias Rivera, Travis Josephs, Shilpa Jain, Wasseem Skef, Tara Keihanian, Salmaan Jawaid, Wasif Abidi, Kalpesh Patel, Mohamed O Othman, Fares Ayoub

Faculty, Staff and Students Publications

Background: The diagnosis of autoimmune pancreatitis (AIP) can be challenging due to nonspecific symptoms, low sensitivity of serologic markers, and some overlap in presentation with pancreatic ductal adenocarcinoma (PDAC). We aimed to quantify delays in the diagnosis of AIP and identify factors associated with diagnostic delay.

Methods: This was a single-center retrospective study between 2013 and 2023 of adult patients diagnosed with type 1 AIP based on HISORt criteria. Patients were compared to a randomly selected group of controls with PDAC. Data on clinical presentation, lab results, imaging, procedures, and initial treatment regimen were collected. Timing to diagnosis and predictive …