Digital Commons Network^™

Psychotherapy And Changes In Adult Attachment: A Systematic Review, Meghan Kussman

Theses and Dissertations

Attachment insecurity is a transdiagnostic vulnerability factor linked to a wide range of emotional and relational difficulties. Although early attachment patterns tend to be relatively stable, research indicates that attachment orientations can change over time, particularly in response to significant relational or therapeutic experiences. This systematic review examined 39 empirical studies published between 2000 and 2024 to determine whether engagement in psychotherapy is associated with changes in adult attachment security. Eligible studies assessed attachment both pre- and post-treatment using validated self-report measures (e.g., Experiences in Close Relationships Scale; ECR) or interview-based measures (e.g., Adult Attachment Interview; AAI), and reported statistically …

Purpose-Driven Curriculum For 9th-12th Grades For Adulthood Careers & Life Gratification, Destiny Krystle Chioma Nnadozie

Theses and Dissertations

A purpose-driven or purpose-based curriculum is not the standard required for high schools in the United States. Students in grades 9th-12th are educated based on a curriculum that covers mathematics, English, science, and social studies (De Roux & Riehl, 2022; Xiao et al., 2018). The unique individual purpose of each student, realized while in high school, is not considered a priority, leaving students to enter their adult careers lacking true career fulfillment due to this misalignment (Baroudi et al., 2017; S. Lyons et al., 2015; H. Wu, 2024).  Using a qualitative systematic review research design, this study aimed to explore …

The Influence Of Fictional Storytelling On The Student Experience In A Gamified Classroom, Arrash Jaffarzadeh

Theses and Dissertations

This exploratory case study evaluated how the use of gamification and game-based learning (GBL) with the added element of storytelling affected engagement and attitudes of children ages 9 to 13 as they participated in quests to complete their learning objectives.  Archived artifacts of a computer technology class in a northern California private school using the Applied Computer Technology Education (ACTE) framework taught to grade 4-8 provided the data for the study.  Each quest was comprised of a fictional story that tied to the lesson. These stories involved the three archetypes of the warrior (herald), healer (ally), and mage (trickster) on …

Best Practices Of Vietnamese Catholic Priests Leading Vietnamese Community Parishes In Orange Diocese, Phuc Viet Nguyen

Theses and Dissertations

The Catholic Church is the largest church all over the world and is also the largest one in the United States (Pew Research Center, 2013). Over the past decades, great crises inside the Catholic Church have raised significant concerns for its leadership practices, especially for its governance and administration on the diocese and parish level. Moreover, the issue of immigrants also compounds the problem when there are different ethnic communities inside one single parish. In some dioceses like Orange County, which is one of the most culturally diverse dioceses in the United States (Diocese of Orange, 2018), the urgency of …

Upskilling California’S Public Health: An Assessment Of An Online Data Science Program, Michelle Ruiz

Theses and Dissertations

The COVID-19 pandemic exposed critical gaps in public health workforce data capabilities, prompting increased investment in data science training. This instrumental case study examined the effectiveness of University of California, Berkeley School of Public Health's online data science training program, developed in partnership with the California Department of Public Health to strengthen the state's public health workforce. The study analyzed program artifacts collected between October 2023 and September 2024, including Course Analytics Reports documenting enrollment patterns and Course Evaluation Reports structured according to considering the first two levels of Kirkpatrick's Four-Level Training Evaluation Model (1994). Analysis of nine courses revealed …

Lifelong Learning And Perceived Quality Of Life: An Exploratory Study Of Older Adult Learners In Southern California, Guadalupe Salgado-Shower

Theses and Dissertations

This exploratory study examines the impact of lifelong learning programs (LLPs) on the perceived quality of life among older adults (OAs) against a global demographic shift towards an aging population (Narushima et al., 2018). With the number of people aged 60 and above projected to nearly double by 2050, understanding and enhancing the well-being of OAs has become imperative (United Nations, 2019). Lifelong learning (LL), involving the continuous acquisition of knowledge and skills irrespective of age, emerges as a promising avenue for improving cognitive functioning, social engagement, and emotional well-being among OAs (Longworth & Davies, 2017). This exploratory study adopts …

Student Success, Suicide Rates: A Correlational Study Of Pressures On, And Expectations For High School Students In The United States, Matthew Baham

Theses and Dissertations

Suicide among high school students has become a growing health crisis, with mental health issues such as anxiety, depression, and suicidal ideation increasing at an alarming rate. The purpose of this quantitative research is to explore the correlation between high school graduation requirements, pressures associated with college applications, and rising suicide rates among high school aged students in grades 9 through 12. With the increase in academic demands, standardized tests, extracurricular activities and a competitive college admissions process, has created an enormously high-pressure environment in high school education. These stressors are shown to have an intense impact on high school …

Latina Physician Assistants In Clinical Leadership Roles: Motivations, Challenges, And Insights, Ana Ruiz-Peña

Theses and Dissertations

Despite the rapidly growing Latino population in the United States, only a few of them are physicians, physician assistants (PAs), or nurses. This limited representation becomes smaller with Latina PAs in clinical leadership roles, leading to a health disparity that could negatively impact the health care of the Latino community. To gain a deeper understanding of this issue, the researcher conducted a phenomenological qualitative study examining the lived experiences of Latina PAs in clinical leadership roles, focusing on their motivations, challenges, and strategies for overcoming these barriers. The study was theoretically grounded in theories related to culture, gender, and socioeconomic …

Teacher Stress, Well-Being, And Adaptation To Innovation, Amanda Leanore Pelloth

Theses and Dissertations

Teachers face many sources of stress; however, a consistent source is prompted by the need to cope with change as districts adapt to shifting paradigms. This study intended to fill Rogers’ (2003) KAP gap and the failure of innovations by infusing the study of well-being and emotion into the narrative by incorporating the transactional relationship between technostress and implementation efforts into the technochange process. The study investigated teachers’ cognitive appraisals of technochange (primary appraisal) and their adaptational coping processes (secondary appraisal) to understand how implementation impacts teachers’ well-being and their adaptive processes. A parallel convergent mixed methods approach with an …

R&D Efficiency Of Drug Development At Universities, John Aylworth

Theses and Dissertations

Research and development (R&D) efficiency in the pharmaceutical industry is a measure of the relative value of new and novel products cast against the costs required to make them. For six decades, the R&D efficiency of large pharmaceutical companies has declined to critical levels. Most recently, nearly half of the companies studied were experiencing negative R&D efficiency, or products whose costs to bring to market outweigh the value they offer both commercially as well as to the health and well-being of society (Schuhmacher et al., 2023). One of the most prominent consequences of the inefficiencies plaguing the drug development industry …

The Cognitive And Positive Aspects Of Language Brokering Among Latinx Individuals: An Integrative Systematic Review, Jacqueline Juarez

Theses and Dissertations

English has been the prominent language spoken in the United States; however, with the rise of the Spanish language, it is imperative to address how Spanish speakers navigate spaces. Research has found mixed findings about the outcomes of serving as a language broker. This integrative systematic review aimed to identify and analyze literature on Latinx language brokers regarding cognitive strategies and abilities and the positive processes and perceptions that contribute to enhancing mental health. This review also sought to focus on factors that may contribute to resiliency over time for Latinx language brokers. A total of 31 studies were included …

The Use Of Humor In Mental Healthcare: A Systematic Review, Blake Song

Theses and Dissertations

Humor has been observed, practiced, and documented as an essential feature of society for thousands of years. However, there is still no formalized or widely referenced clinical guidance on how to effectively and appropriately utilize humor in mental healthcare despite ample research over the last 70 years noting the many potential benefits. This lack of guidance may, at least in part, be due to unresolved concerns pertaining to the use of humor in counseling and healthcare settings. For instance, humor is believed by some to be potentially distracting or undermining to the counseling process if used inappropriately. This continued absence …

Self-Compassion And Leadership Effectiveness At Work, Janette Muñoz

Theses and Dissertations

Leaders are currently facing unprecedented times in the workforce, with rapid technological advancements, complexity with geopolitical implications and economic fluctuations, and employee disengagement. Through these changes, leaders are expected to make business decisions, guide their teams, and deliver business results. To navigate these complexities, the role of business leaders is evolving, making self-compassion and associated practices potentially important for leaders. Complexity and the speed of change may lead to an increase in challenges and mistakes experienced at work, actual or perceived, which may lead to decreased internal capacity, higher stress and potentially burnout. This study explores the relationship between self-compassion …

Structural And Functional Analysis Of Translation Inhibition By Betacoronavirus Non-Structural Protein 1, Michael Brandon Vetick

Yale Graduate School of Arts and Sciences Dissertations

humans: SARS-CoV, SARS-CoV-2, and MERS-CoV. Key to their viral lifecycle is Non-structural protein 1 (Nsp1), an essential pathogenicity factor that potently restricts the cell’s antiviral response. Despite poor protein sequence conservation of Nsp1 between evolutionarily distant β-CoVs, these proteins have proven to be highly conserved both functionally and structurally. Nsp1 functions by inhibiting host gene expression through contacts made with two mRNA ribonucleoprotein (mRNP) complexes: the initiating ribosome and the Nxf1/Nxt1 mRNA nuclear export complex. It is believed that two Nsp1 functions occur on the ribosome: Nsp1 is able to coordinate cleavage of the host mRNA and Nsp1 is able …

On Developing A Behavioral Paradigm To Measure Intolerance Of Uncertainty: The Ambiguous Approach Index, Heather Clark

Electronic Theses and Dissertations

Research in clinical psychology over the last 40 years has solidified intolerance of uncertainty (IU) as an important transdiagnostic etiological and maintenance factor of affective psychopathology. Theoretically, IU is the dispositional cognitive tendency underlying anxiety related avoidance behaviors, such as worry, checking, and hypervigilance which lead to increased functional impairment. IU is associated with increased severity of numerous psychological concerns including anxiety, depression, and other commonly comorbid conditions. Further, higher levels of IU are found in clinical than non-clinical samples, emphasizing its role in mental health outcomes. However, behavioral paradigms used to differentiate between individuals of different diagnostic groups or …

Structure And Function Of Sulfated Fucans And Fucosylated Chondroitin Sulfates: Therapeutic And Mechanistic Insights, Marwa Farrag

Electronic Theses and Dissertations

Glycosaminoglycans (GAGs) are heteropolysaccharides widely exploited in the clinic and as molecular models in biomedical research. Marine-derived GAG analogs, particularly sulfated fucans and fucosylated chondroitin sulfates exhibit unique and diverse glycan motifs that are not found in the typical mammalian GAGs. The distinctive structures of the marine sulfated glycans (MSGs) not only expand the structural landscape of GAG-like molecules but also provide valuable platforms to elucidate structure-activity relationships and explore their potential as novel scaffolds for glycan-based therapeutic development. This dissertation presents the isolation, structural characterization, controlled depolymerization, and functional evaluation of several MSGs, highlighting their therapeutic potential, particularly those …

On Planar Brownian Motion Singularly Tilted Through A Point Potential, Barkat Mian

Electronic Theses and Dissertations

We construct a family of time-inhomogeneous two-dimensional diffusion processes, defined over a finite time interval [0, T]. These diffusions have transition density functions that are given by the integral kernels of the semigroup corresponding to the two-dimensional Schrödinger operator with a point potential at the origin. Although, in a few ways, our processes of interest are closely related to two-dimensional Brownian motion, they have a singular drift pointing in the direction of the origin that is strong enough to enable the possibility of visiting there with positive probability. Our main focus is on characterizing a local time process at the …

"Keep Coming Back!": How Recovering Addicts Use Narcotics Anonymous For Social Rehabilitation., Taylor Leigh Ransom

Electronic Theses and Dissertations

This study examines the role of Narcotics Anonymous (NA) in shaping identity transformation and social reintegration among individuals in recovery. Using an ethnographic approach, including participant observation at NA meetings and semi-structured interviews with members, along with textual analysis of Narcotics Anonymous literature, this research explores how NA fosters social recovery by providing a structured yet flexible space for identity reconstruction. Through shared narratives, rituals, and peer support, members navigate the transition from an “addict” identity to one centered on personal accountability, community, and long-term abstinence from drugs.

By situating NA within broader sociological discussions of addiction recovery, social capital, …

Beyond Guns Vs. Butter: Gendered Dynamics In Security Policy Preferences, Elaine Elizabeth Tagert

Electronic Theses and Dissertations

This dissertation challenges the foundational assumptions of the “guns versus butter” debate by recentering gender, insecurity, and state legitimacy in the analysis of public opinion. Drawing on over 300,000 individual responses across 80 countries, and original survey data from post-conflict Colombia, it demonstrates that the commonly held belief that women are more likely to prioritize welfare over security is both context-dependent and empirically unstable. Rather than reflecting innate preferences, gendered policy attitudes emerge from lived experiences of violence, inequality, and institutional trust.

The first empirical chapter reveals a striking reversal of conventional expectations in the Global South: in regions where …

Measurement Of Forces In Standing Wave Ultrasonic Fields, Milan Rai

Electronic Theses and Dissertations

The acoustic radiation force provides the physical mechanism for the non-contact levitation and manipulation of particles in ultrasonic standing wave fields. This thesis presents a study on the measurement, simulation, and validation of acoustic radiation forces acting on spherical particles levitated in air. The motivation for this work is to provide high-precision measurements of acoustic radiation forces in trapping systems, which are of particular interest in biomedical manipulation, materials science, and contactless assembly.

The study employs a three-part methodology: theoretical analysis, experimental observation, and numerical simulation. Theoretically, the acoustic radiation force was derived from Gor’kov’s potential (valid for ka « …

Navigating The Neighborhood: Community, Identity, And Gentrification In Crown Heights, Brooklyn, Kayla Karyl Thomas

Yale Graduate School of Arts and Sciences Dissertations

Crown Heights, Brooklyn, New York. This dissertation is a multi-method community study focusing on 21st century gentrification, concurrent socio-political changes, and their relationship to the ways residents understand and negotiate routine interpersonal relationships. The empirical core of the dissertation consists of three distinct yet interrelated papers on the social landscape of the contemporary Crown Heights neighborhood. These papers detail a range of approaches that residents adopt to better understand their own experiences of discrimination, gentrification, and efforts at reconstructing community and responding to change. Complemented by a chapter on the history of a single ‘representative’ Crown Heights apartment building, its …

Majority Dynamics On Random Graphs With Almost Balanced Initial Settings: The Power Of Few, Hoang Bao Linh Tran

Yale Graduate School of Arts and Sciences Dissertations

A community of n people participate in a parliamentary election with two major parties. Every person initially supports one side, and with each day, changes their opinion to match the majority among their friends. This process, commonly known as Majority Dynamics in literature, and similar processes, have been studied in many different contexts, including Statistical Physics, Computer Science, Economics and Ecology, as discussed in the influential survey by Mossel and Tamuz (2014).

Tran and Vu (2019) considered the process on a Erdös-Rényi G(n, p) random graph and discovered the "Power of Few" phenomenon: Starting from a …

Leveraging Large-Language Models As Collaborative Reasoning Partners To Enhance Scientific Workflow, Douglas B. Craig

Wayne State University Dissertations

The rise of Large Language Models (LLMs) has transformed artificial intelligence, offering advanced capabilities in text generation, natural language understanding, and multi-modal interactions. However, their use as standalone tools or as perceived repositories of static knowledge has limited their potential in real-world applications, especially in critical domains like healthcare and scientific research, where transparency, explainability, and accountability are paramount. This research addresses these limitations by conceptualizing LLMs as reasoning engines within a hybrid framework that integrates retrieval-augmented generation (RAG) and case-based reasoning (CBR) within a note-taking application.

The study introduces a novel system, LmRaC, designed to enhance the reliability, explainability, …

Using Genetically Heterogenous Mice To Identify Regulators Of Immune Checkpoint Blockade Response, Justin Hackett

Wayne State University Dissertations

Immune Checkpoint Inhibitors (ICI) have dramatically improved patient outcomes in metastatic lung cancer, metastatic melanoma, subtypes of renal cancer and others. However, despite the clinical success, most patients still fail to have a durable response. Understanding what determines response and predicting who will respond to therapy is essential to improving patient outcomes. To investigate genetic underpinnings of ICI response we utilized F1 crosses of C57Bl/6 with Diversity Outbred mice (DOB6F1) and multiple Collaborative Cross (CC) strains to identify and validate (respectively) genetic loci that associated with response to ICI. The genomic data suggested that the lactation and immunomodulatory peptide prolactin …

The Role Of Fruiting Bodies In Protecting A Community Of Myxococcus Xanthus Spores From The Environment, Dave Lall

Wayne State University Dissertations

Environmental microorganisms have evolved a variety of strategies to survive fluctuations in environmental conditions, including the production of biofilms and differentiation into spores. Myxococcus xanthus are ubiquitous soil bacteria that produce starvation-induced multicellular fruiting bodies filled with environmentally resistant spores (a specialized biofilm). Isolated spores have been shown to be more resistant than vegetative cells to heat, ultraviolet radiation, and desiccation. The evolutionary advantage of producing spores inside of fruiting bodies is not clear. Here, we examine a hypothesis that the fruiting body provides additional protection from environmental insults. We developed a high-throughput method to compare the recovery (outgrowth) of …

Environmental Pollution And Early-Life Metabolic Programming, Lisa Koshko

Wayne State University Dissertations

Substantial evidence demonstrates that parental pollutant exposures can induce harmful health effects in the offspring, including the predisposition to Type II Diabetes. As rates of Type II Diabetes continue to rise in younger populations, a crucial gap lies in understanding the role of parental influence in the etiology of later-life metabolic disease. Therefore, the central goal of this work was to determine how early life exposure to smoking level benzene, an endocrine-disrupting air pollutant, affects the metabolic health of offspring, and to identify potential developmental mechanisms involved in disease susceptibility. This goal was achieved using two models of early life …

The Category Is: Body: A Pcsim Approach To Culture-Specific Bid Healing Programming For Bgcm, Gabriel A. Delong

Wayne State University Dissertations

Black gay cismen (BGCM) are among the highest population demographics to experience body image dissatisfaction (BID) and among the least likely to seek healing programming. Culture-specific experiences such as sexual racism have been linked to body image dissatisfaction among BGCM. While the harmful experiences of sexual racism have been studied among BGCM, body image healing programming continues to address the needs of predominantly White straight ciswomen. Additionally, medical mistrust, identity preservation, and culturally incongruent healing practices have been linked to reasons BGCM are reluctant to seek healing practices. This dissertation aims to address the gap in existing literature by employing …

The Association Of Vitamin D Status In Us Adults With Depression: Nhanes 2011 - 2018, Joshua A. Yearout

All Master's Theses

ABSTRACT

Background: Vitamin D (VD), essential for bone health and various physiological processes, has been increasingly associated with mental health, particularly depression. Depression is the most common and prevalent of disorders regarding mental health. It is influenced by biological, psychological, and socioeconomic factors. This study examines association and the interplay of both vitamin D deficiency (VDD) and depression among adults 18- 70+ residing in the U.S, focusing on disparities across demographic and socioeconomic groups.

Methods: Data was taken from the National Health and Nutrition Examination Survey (NHANES) 2011–2018. The present study utilized a cross-sectional analysis included 7,981 participants aged 18 …

Phytochemistry Of Dalea Candida Var. Oligophylla, Ryan E. Galperin

All Master's Theses

The focus of this project was the plant Dalea candida and its phytochemistry. The plant compounds were isolated and purified by an array of chromatographic techniques. The structures of the pure compounds were determined by one-dimensional and two-dimensional ¹H and ¹³C NMR spectroscopy, supported by infrared and ultraviolet spectroscopy, experimental and calculated circular dichroism spectroscopy, and mass spectrometry. Plant parts were worked on separately since they typically differ in content. Purified compounds will be tested for biological activities. Based on our results, eight new or known compound were isolated, specifically four new compounds and four known compounds. Compound …

Designing For Neurodiversity In Web Spaces, Kelly Getz, Kimberly Shotick

Faculty Books & Book Chapters

In this chapter, we share how we carried out library website usability studies with neurodivergent students. The research is situated within the Social Model of Disability and places value on students' experiences challenges. Through usability studies and inclusive web service redesign plans, we center the opinions and expectations of neurodivergent student users in ways neurotypical users have been centered and designed around in the past. The chapter will share methods and best practices for conducting usability studies with neurodivergent individuals as well as findings from our own study.