Digital Commons Network^™

Geometric Modeling, Reconstruction And Evaluation Of Maize Leaf Morphology In 3d, Zhaocheng Xiang

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Maize is a vital crop for global food security, yet quantitative characterization of its three-dimensional (3D) morphology remains a major challenge due to the geometric complexity of curved leaf structures and occlusions during data collection. This work presents an integrated framework for the digital reconstruction, parametric modeling, and functional analysis of maize leaf morphology and canopy architecture, advancing the precision and interpretability of phenotyping and modeling in smart agriculture.

First, we propose a descriptive and parametric model that represents maize leaves through three fundamental components: midrib, cross-section, and blade contour. Each is described by geometric curves and controlled by biologically …

Assessing Reproductive Health In Zoo-Managed African Elephant Bulls (Loxodonta Africana), Kaitlyn Marie Campbell

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Populations of zoo-managed African elephant (Loxodonta Africana) exhibit substantial individual- and population-level variation in reproductive success, yet research has largely focused on females, leaving male fertility poorly understood. Subfertility in bulls, characterized by low libido and inconsistent semen quality, poses significant challenges to genetic management and long-term population sustainability. This study a) systematically evaluates semen quality, b) identifies physiological, behavioral, social, and environmental determinants of fertility, and c) advances ex situ conservation through the expansion of the African elephant sperm bank. Between January 2023 and July 2025, 209 semen collection events were conducted from 13 sexually mature bulls …

Leaf-Based Varietal Categorization Of Sweetpotato (Ipomoea Batatas L. Lam.), A Potentially Healthful Vegetable, Using Image Processing And K-Means Clustering, Shahidul Islam, Md Towfiqur Rahman, Md Hamidul Rahman, Abdul Momin

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Sweetpotato (Ipomoea batatas Lam) leaves contain higher concentrations of phenolic compounds, flavonoids, and carotenoids that are remarkable in health promotion. However, the nutrient content in sweetpotato leaves varies from variety to variety, and leaf shape and color are the key identifying factors for the varietal classification of sweetpotatoes. So, detecting sweetpotato leaves is essential for the in-situ identification of sweetpotato varieties and for developing intelligent agricultural systems. This study aimed to create a leaf-shape-based varietal classification technique for sweetpotato using image processing techniques coupled with a K-means clustering algorithm. 38 leaf images (RGB) of two sweetpotato cultivars were collected …

In-Season Nitrogen Mmanagement: Leveraging Data Visualization For Precision Agriculture, Chathurika Harshani Narayana

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Effective nitrogen management is vital for sustainable agriculture, impacting both crop yield and environmental health. Traditional methods often use fixed application rates set before planting, which do not adapt to changing crop needs during the season. This can lead to over- or under-application, reducing efficiency and sustainability. While modern tools like sensors, satellites, and UAVs provide valuable real-time data on crop and field conditions, integrating and using this data to guide timely nitrogen decisions remains a major challenge. In-season nitrogen management offers a solution by allowing for dynamic adjustments to nitrogen applications, addressing crop needs as they arise. This approach …

Ber Anena’S Vagina Diaries, A Review: An African Student’S Encounter With The American Health System, Akua Agyeiwaa Denkyi-Manieson

Department of English: Dissertations, Theses, and Student Research

This work delves into the disappointment, indifference, and pretense experienced by the narrator when she sorts the American healthcare system. It also addresses the struggles immigrants face, particularly from Africa, as they navigate a healthcare system that often requires them to prove their pain and worthiness of attention. The narrative emphasizes the importance of not generalizing the entire healthcare system based on a single negative experience while acknowledging the profound impact on one's perception of the system. Furthermore, it explores the paradox between the availability of better resources in America compared to the narrator's home country and the mistreatment and …

Personalized Versus Fixed Tactile Cueing In Parkinson’S Disease: Protocol For A Randomized Controlled Trial On Gait Automaticity, Pablo Burgos

Faculty Publications - College of Physical Therapy

Background

Gait automaticity, the ability of the brain to control locomotion with minimal use of executive-attentional resources, is altered in people with Parkinson’s disease (PD). Recently, we showed that step-synchronized tactile cueing improved gait regularity and freezing of gait in PD; however, it is not known if this cueing mode also improves gait automaticity. Thus, this study investigates the effects of step-synchronized tactile cueing (versus fixed cueing) on gait automaticity in the laboratory and during daily life.

Methods

This is a pilot, randomized, double-blinded study where sixty participants with PD will be randomized into one of two, cueing interventions: 1) …

Renewal Of Cocaine Seeking Using Social And Nonsocial Contextual Stimuli, Bree A. Humburg, Michael T. Bardo

Psychology Faculty Publications

Rationale Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.

Objectives This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.

Methods In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction …

A Historic Case Of Relapsing-Remitting Alzheimer's Disease In An Adolescent Attributed To Scarlet Fever., Richard Lathe, Brian J. Balin

PCOM Scholarly Works

We draw attention to a historic case of a boy who suffered from scarlet fever (typically caused by the bacterium Streptococcus pyogenes) at age 7 years and went on to develop the symptoms of Alzheimer's disease (AD). His physicians believed that the subsequent dementia was related to the infection. After death at 24 years of age, postmortem brain examination revealed abundant AD-type senile plaques and fibrils, formally confirming AD. Other potential causes of early-onset dementia are discussed, but these are distinct from patient E.H. This case is pertinent regarding the current debate about the potential role of infection in …

The Potential Of Oral Cavity Bacterial Relative Abundance Index For Determining The Severity Of Dental Caries, Masyhudi, Krishna P. Candra, Esti H. Hardi, Aman S. Panggabean, Islamuddin Ahmad, Hadi Kuncoro, Rudy A. Nugroho

Journal of Dentomaxillofacial Science

No abstract provided.

Preliminary Evaluation Of Bahamian Botanicals For Tropical Applications, Michelle Antoinette Outten

Selected Full-Text Master Theses 2021-

This thesis explores the phytochemical composition and cosmetic potential of three Bahamian botanicals- Mosiera longipes (MLE), Tabebuia bahamensis (TBE), and Momordica charantia (MCE)---traditionally used in local bush medicine. Methanolic and aqueous extracts were prepared and incorporated into topical cream formulations. While HPLC-DAD analysis was performed, no compounds were definitively identified due to hardware limitations; chromatographic data remain preliminary, providing a foundation for future validation. Formulations were assessed for stability under centrifugation, thermal cycling, and long-term storage. All samples demonstrated acceptable initial pH values within the skin-compatible range (4.5-5.5): BWE (5.63 ± 0.04), TBE (5.47 ± 0.02), MLE (5.72 ± 0.04), …

Strategic Identification Of Prognostic Biomarkers For Knee Osteoarthritis Via Optimized Regression Techniques, Varun Sri Sai Vemuri

Selected Full-Text Master Theses 2021-

Knee Osteoarthritis (KOA) is a progressive musculoskeletal disease involving cartilage matrix degradation, subchondral bone remodeling, and systemic inflammation, significantly impairing joint function and mobility. Existing KOA prediction models are not designed to account for nonlinear multimodal biomarker interactions or to integrate biochemical and imaging data, thus limiting their clinical utility. The current method for early detection and prediction of KOA disease progression is primarily based on machine learning-based approaches using radiographic imaging data, static feature selection, and deterministic outputs. These machine learning approaches often fail to capture the pathophysiology of KOA disease progression, which involves a complex cascade of processes, …

Bs Public Health Community Health, Public Health

Program Revisions/Additions

No abstract provided.

Toll-Like Receptor Signaling In Neurons Modulates C. Elegans Feeding Behavior In A Hunger State-Dependent Manner, Neel Patel, Joseph Rios, Retwika Ganguly, Cindy Mutafoglu, Nour Shalash, Karla Gallardo, Malak Saleh, John Chahine, Emily Kopecky, Gursimran Gujral, Kamya Shah, Christos Suriano

Department of Biology Faculty Scholarship and Creative Works

Animals face the risk of encountering pathogenic microbes while foraging for resources. Assessing the risk of nutrition vs. infection can result in the behavioral regulation of immune processes. Behavioral immunity in the nematode roundworm Caenorhabditis elegans (C. elegans) is regulated, in part, by the innate immune molecule TOL-1: a homolog of vertebrate Toll-like Receptor (TLR) proteins that influences C. elegans pathogen avoidance behaviors by promoting the development of CO2-detecting chemosensory neurons. While TOL-1′s role in pathogen avoidance is well established, its role in an opposing behavior – foraging – has not been examined. In addition to pathogenic bacteria, preferred food …

Voltage-Dependent Anion-Selective Channels 1 And 2 Wild Type And Mutant Bh3-Like Domain Peptides: Analysis Of Secondary Structure And Binding Stoichiometry To Recombinant Bax, Geanell C. Adams

Electronic Theses and Dissertations

Despite national efforts to increase female participation in science, technology, engineering, and mathematics (STEM), women remain significantly underrepresented in collegiate STEM programs. This pilot study sought to identify pre-collegiate factors that influence female students’ decisions to enroll and persist in STEM collegiate programs at the University of Mississippi, a predominantly white R1 research institution using qualitative methods. Grounded in Bandura’s Social Learning Theory, the research examined the environmental, behavioral, and personal determinants that shape academic pathways for women in STEM.

Data were collected through semi-structured interviews with six sophomore female STEM majors. Thematic analysis revealed that early exposure to structured …

Working With Parents/Guardians To Provide Support And Knowledge For Structured Literacy Spelling Instruction At Home, Claire Rearick Fearn

Electronic Theses and Dissertations

This dissertation in practice explores the role of spelling instruction within the framework of the Science of Reading (SOR) and Structured Literacy (SL). This research examines how spelling, a vital yet acquired literacy skill, is foundational to reading and writing development and should be taught explicitly and systematically through SL principles. Drawing on research in cognitive neuroscience, developmental psychology, and educational research the study highlights how the brain learns to read and spell, reinforcing the need for evidence-based instruction that integrates both encoding and decoding practices. Despite research starting the importance of teaching spelling utilizing SL methods, spelling instruction and …

An Advanced Machine Learning Framework And Multi-Label Heart Disease Classification With Unet-Based Nucleus Segmentation, Md Rahat Kader Khan

Electronic Theses and Dissertations

The growing demand for accurate, rapid, and interpretable diagnostic tools in the medical field has spurred the integration of artificial intelligence into various healthcare applications. Acute Myocardial Infarction, which remains one of the primary causes of mortality in both developed and developing nations, requires timely and precise identification to prevent life-threatening complications. In response to the lack of interpretable AI models tailored to diagnosing AMI using hemogram parameters, this study presents a robust machine learning-based framework that explores the diagnostic potential of these parameters. By evaluating several machine learning techniques, the research establishes the superiority of boosting algorithms, particularly the …

The Influence Of Pressure, Intensity, And Amount Of Muscle Mass Exercised On Changes In Muscle Size, Strength, And Endurance: A Methodological Investigation, Ryo Kataoka

Electronic Theses and Dissertations

Purpose: To 1) examine the effects of low-load submaximal resistance exercise with blood flow restriction (BFR) on muscle size, strength, cross-education, and local muscular endurance while accounting for proximity to failure under restriction, and 2) determine whether changes in muscle size and strength differ based on the amount of muscle recruited during the exercise bout.

Methods: A total of 177 (18–35 years) participants were randomly assigned to one of five groups: unilateral low-load submaximal elbow flexion exercise 1) with BFR (LL+BFR, n=35), 2) without BFR (i.e., matched for a % of repetition-to-failure under restriction) (LL, n=37), 3) to failure (LL-Failure, …

論周曉楓的生態女性主義書寫──以《有如候鳥》中鳥類意象為例, Siqi Wang

Dissertations from all years

中國當代作家周曉楓以「小說式散文」著稱，其作品融合小說情節的跌宕起伏與散文的非虛構內核。動物題材是她創作的重要部分，通過動物與人的互動，揭示中國當代社會的現象和問題，並融入女性經驗書寫，探討動物與女性之間的神秘聯系及其對生存空間的影響。《有如候鳥》（2017）通過女性生命經驗，講述女性與候鳥的聯系，是中國當代文學中首次顯著體現生態女性主義的作品。

本文從生態女性主義理論出發，分析《有如候鳥》中的三個代表性鳥類意象：大雁、鷗鳥和鴿子。大雁象征女性意識的啟蒙；鷗鳥隱喻女性在當代社會中的多重生存處境；鴿子則關聯女性的離散與再生。這些意象展現了女性與自然的共同困境，反映了中國當代女性面臨的壓迫與挑戰。

本文分為五部分：緒論介紹作家背景、理論框架及研究意義；第二至四章分別分析三種鳥類意象；結語總結全文觀點。

Voting With Their (Left And Right) Feet: Are Homebuyers’ Values Of Neighborhood Environmental Amenities Consistent With Their Politics?, Corey Lang, Jarron Vanceylon

Environmental and Natural Resource Economics Faculty Publications

There exists a consistent partisan gap in preferences for public spending on the environment, with approval being 20 to 40 percentage points higher for Democrats than Republicans. In this paper, we investigate whether there is a similar partisan gap present in residential preferences for environmental amenities. We link housing data, land use, and household characteristics, including voter registration, for three distinct housing markets, and we develop a residential sorting model to estimate marginal willingness-to-pay (MWTP) for residential proximity to conserved land, allowing for preference heterogeneity by partisanship as well as other household characteristics. For all households combined, we estimate average …

Towards A Missiological Model For Reaching East Indian Muslims For Christ In Kwatta Of Suriname, Kenneth Rigobert

Dissertations DIS

The presence of Seventh-day Adventists in Suriname dates to 1894, but there is no evidence, either in literature or field research, of any specific plan or missional thinking focused on the Adventist mission among East Indian Muslims in Suriname. The field research highlights some significant missiological challenges faced by the Seventh-day Adventist mission in Suriname that account for its slow numerical growth. These missiological challenges include: (1) a lack of committed and dedicated indigenous leaders; (2) inappropriate training given to the indigenous people for the mission in Suriname's multicultural and multilingual dynamics; (3) unsuitable missional methods for Suriname’s multicultural and …

Microbial Mavericks: Turning Hazards Into Snacks, Alison G. Blanton

Biology Dissertations - Archive

Symbiotic associations with microbes are widespread across life and provide hosts with essential and beneficial functions. A growing concern in pest management is symbiont-mediated detoxification (SMD), a form of metabolic resistance to insecticides. The best-known example of SMD involves the bean bug Riptortus pedestris, where an environmentally acquired but obligate Caballeronia symbiont confers resistance to the organophosphorus insecticide fenitrothion. Motivated by this model, I began my work in another known bug-Caballeronia symbiosis: Leptoglossus phyllopus, native to the United States. I then expanded the study to include two additional U.S.-native hosts, Leptoglossus zonatus and Anasa tristis. Representative …

Interspecific Interactions And Resource Availability As Drivers Of Species Occurrences, Edita Folfas

Biology Dissertations - Archive

Understanding what forces determine species occurrence is central to studies of community ecology. Species interact with each other and their environment, and these interactions scale up to shape global patterns of diversity. In my first chapter, I examined how predation might shape patterns of Anolis lizard species richness and abundance across landscapes on islands in the Greater Antilles. I quantified predatory bird occurrence by using thousands of observations from an online citizen science database (eBird). I then obtained estimates of anole abundance and diversity by conducting local field surveys and using mark-resight methods. While predators could negatively impact anole abundance …

Comparative Effectiveness Of Conservative Versus Early Surgical Treatments On Wound Healing Outcomes Of Diabetic Foot Ulcers: A Literature Review, Paul Tran, Yasim Zafar, Andrea Piña, Stephanie N. Campbell

School of Podiatric Medicine Publications

Diabetic foot ulcers (DFUs) are a severe complication of diabetes mellitus and the leading cause of lower extremity amputations worldwide. Peripheral neuropathy and peripheral arterial disease secondary to complications of diabetes mellitus may result in ulcers going unnoticed, increasing the risk of severe osteomyelitis, necrotizing infection, hospitalization, amputation, and sepsis. While conservative management of DFUs remains the first-line approach—emphasizing wound care, infection control, glycemic management, and offloading—there is growing debate about whether delaying simple surgical interventions worsens long-term outcomes. Surgeries such as tenotomy, digital amputation, and tendo-Achilles lengthening are minimally invasive options that can correct deformities, prevent recurrence, and promote …

Membrane Filtration Of Nanoscale Biomaterials: Model System And Membrane Performance Evaluation For Aav2 Viral Vector Clarification And Recovery, Mara Leach, Kearstin Edmonds, Emily Ingram, Rebecca E. Dutch, Ranil Wickramasinghe, Malgorzata Chwatko, Dibakar Bhattacharyya

Chemical and Materials Engineering Faculty Publications

The growing demand for viral vectors as nanoscale therapeutic agents in gene therapy necessitates efficient and scalable purification methods. This study examined the role of nanoscale biomaterials in optimizing viral vector clarification through a model system mimicking real AAV2 crude harvest material. Using lysed HEK293 cells and silica nanoparticles (20 nm) as surrogates for AAV2 crude harvest, we evaluated primary (depth filters) and secondary (membrane-based) filtration processes under different process parameters and solution conditions. These filtration systems were then assessed for their ability to recover nanoscale viral vectors while reducing DNA (without the need for endonuclease treatment), protein, and turbidity. …

Cardiac Injury Regulates Neuroinflammation Through Extracellular Vesicle–Mediated Heart-Brain Crosstalk, Qingxuan Li, Ramzi H. Hamdalla, Neha Dhyani, Lijun Sun, Lie Gao, Tara L. Rudebush, Irving H. Zucker, Changhai Tian

Toxicology and Cancer Biology Faculty Publications

Cognitive impairment is common in heart failure patients, contributing to morbidity and mortality. This impairment may be linked to neuroinflammation in heart failure. However, the primacy of the heart-brain axis remains to be completely understood. Here, we elucidate the potential effects of myocardial injury on pathways and inflammatory mediators responsible for cognitive impairment using a rodent myocardial injury model. The results demonstrate direct extracellular vesicle (EV)-mediated heart-brain crosstalk and the glial uptake of cardiac EVs. In addition, brain inflammation was also elicited following myocardial injury. Moreover, cardiac EVs promote brain microglial cell activation in vitro, potentially mediated by EV-enriched micro-RNAs …

A Community Effort To Develop Common Data Elements For Pre-Clinical Spinal Cord Injury Research., Britt A. Fedor, Abel Torres-Espin, Romana Vavrek, Maryann E. Martone, John L. Bixby, John C. Gensel, Vance Lemmon, Jeffrey S. Grethe, J. Russel Huie, Adam R. Ferguson, Karim Fouad, The Preclinical Sci Common Data Elements (Cde) Workshop Participants

Spinal Cord and Brain Injury Research Center Faculty Publications

For nearly 350 years, the process of disseminating scientific knowledge has remained largely unchanged. Scientists conduct experiments, analyze the data, and publish their findings in the form of scientific articles. Since the turn of the century, this process has been challenged by numerous open science and data sharing efforts to enhance transparency, reproducibility, and replicability of scientific research. Big data approaches, together with machine learning and artificial intelligence, are frequently used to gain insight into the ever-growing complexity of biological systems and biomedical research. To utilize these approaches and harness the continuously increasing computational power requires data to be both …

Cross-Species Comparisons Between Pigs And Mice Reveal Conserved Sex-Specific Intraspinal Inflammatory Responses After Spinal Cord Injury, Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. Maclean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel

Spinal Cord and Brain Injury Research Center Faculty Publications

Objective Therapeutic translation is challenging in spinal cord injury (SCI) and large animal models with high clinical relevance may accelerate therapeutic development. Pigs have important anatomical and physiological similarities to humans. Intraspinal inflammation mediates SCI pathophysiology. The purpose of this study was to evaluate the effect of sex on inflammation and outcomes in a pig thoracic contusion/compression SCI model.

Methods Adult (gonad-intact) male and female Yucatan miniature swine were subjected to either SCI or sham (laminectomy-only) injury.

Results SCI caused locomotor dysfunction (measured with the Porcine Thoracic Injury Behavior Score) with some recovery over 6 weeks and limited tissue sparing …

Exploring The Links Among Brain Iron Accumulation, Cognitive Performance, And Dietary Intake In Older Adults: A Longitudinal Mri Study, Valentinos Zachariou, Colleen A. Pappas, Christopher E. Bauer, Elayna R. Seago, Brian T. Gold

Neurology Faculty Publications

This study evaluated longitudinal brain iron accumulation in older adults, its association with cognition, and the role of specific nutrients in mitigating iron accumulation. MRI-based, quantitative susceptibility mapping estimates of brain iron concentration were acquired from seventy-two healthy older adults (47 women, ages 60–86) at a baseline timepoint (TP1) and a follow-up timepoint (TP2) 2.5–3.0 years later. Dietary intake was evaluated at baseline using a validated questionnaire. Cognitive performance was assessed at TP2 using the uniform data set (Version 3) neuropsychological tests of episodic memory (MEM) and executive function (EF). Voxel-wise, linear mixed-effects models, adjusted for longitudinal gray matter volume …

Circulating Molecular Drivers Of Bone Remodeling In Pancreatitis, Rachel L. Hill, Dhiraj Yadav, Phil A. Hart, David C. Whitcomb, Kristen J. Mcquerry, Kelsey N. Karnik, Kimberly M. Stello, Darwin L. Conwell, Madhumathi Rao

Internal Medicine Faculty Publications

INTRODUCTION: 

Pancreatitis-associated osteopathy is a clinically significant but mechanistically underexplored complication of pancreatic disease. We aimed to characterize stage-specific alterations in bone remodeling biomarkers across the spectrum of disease: recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP).

METHODS: 

In a cross-sectional analysis of North American Pancreatitis Study 2 participants, we measured serum mechanistic (sclerostin, dickkopf-1, receptor activator of nuclear factor κβ ligand, and osteoprotegerin), hormonal (fibroblast growth factor 23, insulin, and leptin), and modulatory (osteopontin, oncostatin, and osteoactivin) markers in controls (n = 30), RAP (n = 40), and CP (n = 40) using a multiplex assay. Group differences were …

Adverse Childhood Experiences, Depression And Subjective Cognitive Decline By Gender: A Moderated Mediation Analysis, Monique J. Brown, Darlingtina K. Esiaka, Jaya Viswanathan

Behavioral Science Faculty Publications

Studies assessing depression as a mediating factor between adverse childhood experiences (ACEs) and subjective cognitive decline (SCD) are lacking. Therefore, the aims of this study were to: (1) determine the mediating role of depression in the association between ACEs and SCD; and (2) assess the moderating role of gender. Data were obtained from the 2023 Behavioral Risk Factor Surveillance Study (BRFSS) survey (N = 38,600). Crude and adjusted path analyses were used to determine the mediating role of depression between ACEs and SCD. Adjusted analyses controlled for sociodemographic confounders. ACEs were positively associated with depression (B = 0.129, p …