Digital Commons Network^™

Centrality Algorithms For Weighted Homogeneous Multilayer Networks, Ayomide Ayowole-Obi

Computer Science and Engineering Theses - Archive

Applications need to be modeled for analyses. With the availability of many alternate data Models, choosing one needs to be done carefully by considering the complexity of data to be modeled and its analyses requirements. Social networks and other newer applications are primarily relationship-oriented and also have multiple types of entities and relationships. Although simple and attributed graphs have been used historically for modeling these applications, recently, multilayer networks (or MLNs) have been shown to be more effective in preserving the semantics of the application better and further provide flexibility of analyses. However, choice of MLN as a data model …

Crime Theory Informed Agent-Based Modeling For Crime Prediction And Patrolling Route Optimization, Shohreh Moradi

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Crime reduction remains a global priority, demanding both accurate modeling of criminal dynamics and efficient allocation of scarce policing resources. To address these needs, this study presents a two‐fold framework that (1) simulates street‐level crime patterns using an agent‐based model (ABM) grounded in Routine Activity Theory (RAT), Rational Choice Theory (RCT), and Crime Pattern Theory (CPT), and (2) optimizes patrol routing through a time-dependent, multi‐visit mixed‐integer linear programming (MILP) formulation.

In the first component, we integrate real‐world crime, environmental, and census data to reproduce realistic offender, citizen, and Police behaviors, capturing where and when robbery, burglary, and larceny occur across …

Guided-Mode Resonant Nanopatterns For Raman Generation And Photonic Devices, Renjie Chen

Electrical Engineering Dissertations - Archive

This dissertation explores advanced strategies for enhancing Raman amplification in silicon photonic devices, focusing on guided-mode resonance engineering and resonant mode manipulation. Silicon, despite its indirect bandgap, exhibits a strong Raman scattering coefficient, enabling it to function as a viable gain medium for integrated photonic systems. However, the realization of efficient, compact, and low-threshold silicon Raman amplifiers and lasers necessitates innovative design approaches that overcome inherent material and structural limitations.

The first chapter provides a fundamental overview of optics, including physical principles, spectral characteristics, guided-mode resonance, simulation methods, and nanopattern fabrication methods.

The second chapter delves into silicon-based Raman amplification …

Multi-Modal Model-Based Optical Flow Estimation For Event-Based Vision, Pritam Karmokar

Computer Science and Engineering Dissertations - Archive

Event cameras offer a fundamentally different sensing paradigm by asynchronously capturing brightness changes at high temporal resolution, directly encoding motion in the scene. However, their sparse and non-traditional data format poses significant challenges for dense motion estimation, particularly in the context of optical flow. Contrast Maximization (CM) has emerged as a powerful model-based framework for estimating optical flow from event data by optimizing the sharpness of motion-compensated event representations. This dissertation builds upon and significantly advances the CM framework through two complementary contributions.

First, we propose Edge-Informed Contrast Maximization (EINCM), a hybrid approach that augments the traditional events-only CM framework …

Synthesis And Application Of Cu-Based Ultrasmall Nanoparticles For Targeted Glioblastoma Treatment, Ryan T. Hart

Material Science and Engineering Dissertations - Archive

Glioblastoma (GBM) is a highly malignant form of brain cancer with a bleak prognosis. Current maximal treatment involves surgical resection followed by chemo-or radiotherapy. Two critical barriers make treating GBM a formidable challenge. First, the tumor's tendril-like proliferation throughout healthy brain tissue often makes complete surgical removal and conventional radiation insufficient. Second, the blood-brain barrier (BBB), which protects the brain, unfortunately also shields GBM from life-saving anti-cancer drugs. Here, we develop a radioactive nanoparticle-based therapy that directly confronts these limitations, offering a new strategy for GBM treatment.

Prostate-specific membrane antigen (PSMA) is a promising target for glioblastoma (GBM) treatment because …

Improving The Reliability Of Parts Produced Via Laser Powder Bed Fusion Through A Data-Driven Geometry Optimization Methodology, Federico Venturi

Mechanical and Aerospace Engineering Dissertations - Archive

This research aims to qualify the effect of design geometry on quality metrics of additively manufactured (AM) components that define reliability. Through the use of a novel methodology to characterize these quality metrics, AM components are inspected for the presence of defects such as surface roughness notches and porosity. These directly hinder the high-cycle fatigue characteristics demonstrated through the Kitagawa-Takahashi diagram and the El-Haddad model. By demonstrating the effect of geometry through a designed experiment and the adoption of the Murakami square root area parameter and Arola-Ramulu model, the improvement to fatigue life can be quantified. Incorporating this data into …

Intelligent Microfluidic Systems For Precision Manipulation And Real-Time Recognition Via Dielectrophoresis And Deep Learning, Negar Danesh

Mechanical and Aerospace Engineering Dissertations - Archive

This dissertation introduces intelligent microfluidic platforms by combining advanced DEP-based manipulation with real-time visual feedback. A DEP device featuring circular corral traps and dual-plane electrodes enables precise submicron particle trapping, high-resolution particle separation, and cell-particle co-assembly. Simulations and experiments confirm enhanced electric field control and stable confinement. To enable adaptive operation in EWOD systems, a deep learning model (U-Net) was developed for real-time droplet meniscus segmentation. The model achieved 98% accuracy and remained robust under noisy, low-contrast conditions. A live video pipeline was implemented, enabling consistent frame-by-frame feedback for closed-loop control. Together, these innovations establish a foundation for autonomous, high-performance …

Deep Neural Network Models For Heatsink Performance Prediction And Optimization In Single Phase Immersion Cooling: Framework For Future Design Tools And Digital Twin Integration, Braxton J. Smith

Mechanical and Aerospace Engineering Theses - Archive

The rapidly rising computational power of modern computing components combined with the advanced packaging techniques being implemented has resulted in exponentially increasing thermal design powers (TDP) from CPUs and GPUs. Traditional air-cooling methods are approaching their effective cooling limits for many of these components, requiring lower supply air temperatures, higher supply air flowrates, and much larger heatsinks to remain feasible. Transitioning from air-cooling to single-phase immersion cooling offers numerous benefits in thermal performance, data-center size reduction, and energy efficiency. To leverage the merits of immersion cooling, the performance of a given heatsink must be predicted and optimized for best performance …

Validation Of Non-Invasive Methods For The Measurement Of Gonadal And Inter-Renal Steroid Hormones In A Desert-Adapted Amphibian (Scaphiopus Couchii), Alexander T. Baugh, Callie Cho , '23, Alice Onyango-Opiyo , '23, Sophie A. Rodner , '25, Senna Mieth , '25, Daniel Oakes , '24, Liam Halstead , '25

Biology Faculty Works

For aquatic and semi-aquatic vertebrates like amphibians, it is possible to estimate excreted hormone levels using non-invasive methods such as waterborne and salivary sampling. These techniques allow monitoring of endocrine activity over varying, repeated and simultaneous integration periods while minimizing handling-related stress that can ‘contaminate’ hormone estimates, including estimates of baseline glucocorticoids. Here we have validated the extraction and quantification of three steroid hormones (corticosterone, CORT; 17-b estradiol, E₂; testosterone, TST) in Couch’s spadefoots (Scaphiopus couchii)—a desert-adapted anuran of special interest for physiology, evolution and conservation—using non-invasive waterborne and minimally invasive salivary hormone methods. We combined extraction and …

Noncoding Rnas In Nuclear Organization, Thembalami Dube , '24, Dawn M. Carone

Biology Faculty Works

No abstract provided.

Strategies For Enhanced Meg Data Analysis In Clinical Practice And Emerging Frontiers, Pegah Askari

Bioengineering Dissertations - Archive

Epilepsy and dementia are debilitating neurological disorders that pose substantial challenges for patients, caregivers, and healthcare systems. Advances in magnetoencephalography (MEG) and signal processing offer new opportunities to improve diagnostic accuracy, surgical planning, and treatment monitoring. This dissertation presents a unified body of work comprising artifact removal, automated event detection, and deep learning-based biomarker discovery. These approaches collectively enhance the clinical utility of MEG for diverse patient populations.

The first study addresses a significant technical obstacle in the management of drug-resistant epilepsy. Patients receiving responsive neurostimulation (RNS) have historically been excluded from MEG as the data is contaminated by device-related …

Functional Enhancement Of Pancreatic Islets Through Photobiomodulation For Potential Diabetes Therapeutics, Kelli Fowlds

Bioengineering Dissertations - Archive

Islet transplantation is a potential therapeutic route for type 1 diabetic patients facing chronic ketoacidosis and/or hypoglycemia unable to be properly regulated with standard insulin administration. However, successful engraftment is hampered by a multitude of factors. Harvested islets face rapid, substantial degradation due to hypoxia and nutrient depletion once isolated. Transplanted islets are additionally susceptible to the instant blood-mediated inflammatory reaction (IBMIR). This combination of factors leads to more than half of transplanted islets failing to engraft post-surgery. Many areas of research are dedicated to investigating alternative approaches or supplemental treatments to improve the success rate of engraftment and insulin …

Novel Electrophysiological Biomarkers In Pediatric Drug Resistant Epilepsy And Genetic Epilepsy Syndromes, Sakar Rijal

Bioengineering Dissertations - Archive

Pediatric epilepsies, particularly those that are drug-resistant or genetically driven, represent some of the most complex neurological disorders encountered in childhood. Central to their pathophysiology is a disruption in the delicate balance between cortical excitation and inhibition (E/I), often resulting from impaired GABAergic interneuron function. This imbalance manifests as aberrant network dynamics and altered neural oscillations, giving rise to seizures and long-term cognitive impairments. In this thesis, we developed a translational framework to identify electrophysiological biomarkers that (i) assess cortical E/I imbalance and (ii) map epileptogenic zones, with the aim of enhancing diagnosis, guiding surgical planning, and informing therapeutic monitoring …

Vendor-Independent B0 Shimming Framework With Application To Metabolic Mri In Human Gliomas, Mahrshi Jani

Bioengineering Dissertations - Archive

High and ultra-high field MRI and MRSI offer markedly improved signal-to-noise ratio and spectral dispersion, enabling in-vivo characterization of tumor metabolism with unprecedented detail. However, these benefits are tightly coupled to high demands on static magnetic field (B₀) homogeneity, particularly in the brain where susceptibility interfaces near the skull base and paranasal sinuses generate complex, higher-order field perturbations. In glioma patients, additional susceptibility variations arise from surgical cavities, hemorrhage, calcifications, and cystic components, further degrading B₀ homogeneity. As a result, shimming often become the main bottleneck limiting robust, whole-brain spectroscopic imaging and, consequently, our ability to map metabolic …

Small-Scale Green Infrastructure In Urban Networks - Trinity Presbyterian Church As A Pilot Project, Selvana Getsy -

Landscape Architecture Masters & Design Theses - Archive

Rapid urbanization and increasing impervious cover in cities like those within the Dallas-Fort Worth metroplex have intensified flooding, heat, erosion, and declining ecological quality. Although large-scale green infrastructure (GI) interventions are widely recognized as solutions to these issues, small-scale institutional landscapes remain a neglected yet powerful component of urban GI networks. This study functions as a pilot/demonstration project to evaluate the potential of small-scale GI interventions at Trinity Presbyterian Church, Plano, Texas. The goals are to reduce stormwater runoff, provide ecological and microclimatic improvements, increase community engagement, biodiversity enhancement, and environmental awareness in public institutional settings.

The study utilizes a …

Engineered Biomimetic Muscle Graft For Skeletal Muscle Regeneration, Julia O. Aguirre

Bioengineering Theses - Archive

This study aims to develop a synthetic muscle graft that closely mimics the architecture, viscoelastic properties, and bio-signaling characteristics of natural skeletal muscle. By analyzing the native skeletal muscle microstructure, biochemical, and mechanical properties, we establish design parameters for a biomimetic scaffold. The engineered graft integrates tunable mechanical compliance, aligned microarchitecture, and signaling cues to promote cell recruitment, adhesion, proliferation, and maturation. To further enhance biofunctionality, an electrically conductive polymer was incorporated to improve the electrical conductivity, and the graft was loaded with the bioactive lipid signaling mediator “Prostaglandin E2” (PGE2) to support myogenesis during muscle regeneration. The grafts were …

Implementation And Performance Evaluation Of Plastic Road Mix Design In Parking Lot, Ishraq Faruk

Civil Engineering Dissertations - Archive

The uncontrolled proliferation of plastic waste has emerged as a global environmental crisis, with high-density polyethylene (HDPE) constituting a substantial fraction of the waste stream due to its extensive use in packaging and its resistance to degradation. In parallel, asphalt pavements particularly in urban infrastructure such as parking lots experience accelerated deterioration from raveling, rutting, and cracking as a result of thermal cycling, repetitive loading, and inadequate drainage. These converging challenges present an opportunity for innovative, circular-economy-based sustainable pavement technologies that simultaneously improve surface durability and mitigate plastic waste accumulation.

This research investigates the full-scale implementation and monitoring of HDPE …

Assessing Biodiversity For User Experience In Public Parks: Learning From Downtown Dallas, Texas, Amanda A. Esparza

Landscape Architecture Masters & Design Theses - Archive

Biodiversity loss is a pressing global issue, with far-reaching ecological, social, and cultural consequences (United Nations Environment Programme, 2011). The American Society of Landscape Architects (ASLA) recognizes the biodiversity crisis as equal in urgency to the climate crisis and emphasizes the importance of incorporating biodiversity conservation into design practices (Green, 2024). However, regional experiences of the relationship between biodiversity in designed urban landscapes and user experience remain unexplored. The purpose of this research is to gain a general understanding of the level of biodiversity present in downtown Dallas, Texas, public parks and to assess park users’ perceptions and interactions with …

Can Engaging In Social Activities Prolong Life?

Neurosciences

No abstract provided.

Bibliographic Instruction And The Need For “Librarian-First” Oer Repositories, Michael Kirby

Publications and Research

No abstract provided.

Gaps In Knowledge: Topological Insights Into The Structure Of Science, Gavin Engelstad

Mathematics, Statistics, and Computer Science Honors Projects

Understanding scientific development is essential to ascertaining the mechanisms leading us into the future. Building this understanding requires both methodological developments and empirical research. This thesis contributes in both aspects using a topological approach to examine scientific knowledge. The first section presents a new algorithm to find optimal cycle representatives for homological features in complex networks, a context for which we demonstrate existing algorithms can be inadequate. The second section applies a number of topological methods, including our cycle optimization algorithm, to data on individual scientific fields, demonstrating the value of topological approaches and highlighting new insights about how science …

Leveraging Crispr Technology To Model Beta-Propeller Protein Associated Neurodegeneration And Explore Mechanisms Of Neurological Dysfunction, Brandon Lee Meyerink

Dissertations and Theses

Neurons are highly compartmentalized, specialized cells that are foundational to brain function. Moreover, the neurons we have early in life are the same cells that we carry through our entire life. For these cells to stay healthy and functional over this long period, a process called autophagy is used to clear unwanted, toxic, or unneeded materials from the cell. Alterations in autophagy caused by genetic mutations can lead to the death of neurons and neurodegenerative disease. Here, we use CRISPR technology to genetically modify mouse models to generate a model of autophagy associated neurological disease and study the molecular function …

Recruitment, Reprogramming, And Function Of Trpv1+ Sensory Nerves In The Development And Progression Of Head And Neck Cancer, Anthony Restaino

Dissertations and Theses

Head and neck squamous cell carcinomas (HNSCC) are an epithelial cancer prevalent across the world and are divided into two subcategories: human papillomavirus-mediated (HPV+) and carcinogen-mediated (HPV-) HNSCC. These subgroups have distinct patient populations, divergent responses to therapy, and prognoses, however the foundational mechanisms that facilitate these differences are not well understood or defined. Recently, the presence and function of sensory neurons within the tumor environment of various solid tumors has been identified and investigated. Herein, we identify differences in the presence of TRPV1+ sensory neurons and neuron structures in the tumor environment of HPV+ and HPV- HNSCC, correlating with …

Evaluating A Novel Lifestyle Intervention Trial: Mitigating Type 2 Diabetes, Hypertension And Depression In Adults With Intellectual And Developmental Disabilities Living In Adult Family Homes, Matthew Lee Velissaris

Dissertations and Theses

This study evaluated a 90-day lifestyle intervention for nine ambulatory adults with intellectual and developmental disabilities (IDD) residing in three adult family homes (AFHs). The intervention integrated approximately 120 minutes per week of structured exercise, promotion of the Mediterranean-style eating pattern emphasizing whole foods and omega-3–rich seafood, and adjunctive mindfulness-based cognitive therapy. Using a single-group pre–post design, outcomes included a primary endpoint (A1C) and secondary endpoints (systolic and diastolic blood pressure and depressive symptoms assessed by the Glasgow Depression Scale adapted for adults with IDD). Mixed-effects regression analysis indicated that group-level change in A1C was not statistically significant at α …

The Importance Of Fauna-Mediated Sediment O2 Consumption In The Ngom Hypoxic Zone, Hannah Beck, Kanchan Maiti

Faculty Publications

The northern Gulf of Mexico (NGOM) coastal shelf adjacent to the Mississippi and Atchafalaya rivers system experiences strong seasonal hypoxia in the late summer and coupled physical-biological models suggest that hypoxia formation in the NGOM is sensitive to benthic biogeochemical processes. However, the processes driving sediment oxygen consumption and their relationship to bottom oxygen concentration remain enigmatic. This study for the first time concurrently measured in situ total oxygen uptake (TOU) and diffusive oxygen uptake (DOU) during two different hypoxia seasons. The relatively large DOU: TOU ratio of 0.33 ± 0.07 observed during this study suggests more significant benthic infauna …

Sustainable Agricultural Alternatives To Cope With Drought Effects In Semi-Arid Areas Of Southern Mozambique: Review And Strategies Proposal, Celso Mondlhane, Lawrence Munjonji, Íris Victorino, Carlos Huenchuleo, Paula Pimentel, Pablo Cornejo

All Grantees Publications

Drought, pests, soil fertility depletion, environmental challenges, and the limited use of agricultural inputs continue to plague food production in many developing countries such as Mozambique. As a response to these production constraints, sustainable strategies must be defined to cope with these problems. One strategy, largely applied worldwide, is the combination of the usage of plant growth-promoting microorganisms, conservation tillage, intercropping, and crop residue management. The above can help smallholder farmers to become more resilient, sustainable, and productive, in a framework where the limitations imposed by global climate change are being exacerbated. The impacts of these strategies are less known …

Prevalence And Factors Influencing Eating Disorders Among Post-Bariatric Surgery Patients In Saudi Arabia: A Cross-Sectional Study, Saleh A. Alghamdi, Mohammed A. Al Jaffer, Renad A. Almesned, Sadeem D. Alanazi, Alanoud W. Alhnake, Shahad M. Alkhammash, Nuran M. Baabbad

Neurosciences

ABSTRACT Objectives: To examine the occurrence and contributing factors of disordered eating patterns in individuals post-bariatric surgery. It also investigated the impact of these patterns on weight loss outcomes and long-term weight management, focusing on psychological and emotional factors. Additionally, the relationship between body image dissatisfaction and disordered eating patterns was explored. Methods: A cross-sectional study was conducted across multiple medical centers in Saudi Arabia, using self-administered questionnaires to evaluate the prevalence of eating disorders and self-esteem among patients who underwent bariatric surgery in the past five years. Out of 557 respondents, 452 met the inclusion criteria. Results: The study …

Indirect Effects And Context Dependency In Stream Fish Invasions, William K. Annis, Lily M. Thompson, Stephen R. Midway, Julian D. Olden, Brandon K. Peoples

Faculty Publications

Aim: Invasion ecology is replete with a body of well-supported yet contradictory evidence for numerous invasion hypotheses, likely as a result of context dependency. Context dependency in invasion studies can arise in two ways: (1) apparent, when results differ between studies solely due to methodical differences, or (2) mechanistic, when results truly differ due to ecological processes. One form of apparent context dependency occurs when causally linked factors associated with invasion success (hereafter, invasion drivers) either mask or enhance each other's effect on invasion success. Mechanistic context dependency can occur when regional scale processes modify the influence of local scale …

Flood Risk And Mitigation Calculator Tool To Support Decision-Making For Enhancing Community Resilience: A Case Study Of The U.S.A. Gulf Coastal Region, Rubayet Bin Mostafiz, Ayat Al Assi, Arash Taghinezhad, Carol J. Friedland, Robert V. Rohli, Md Adilur Rahim, Christopher T. Emrich, Melanie Gall, Eric Johnson

Faculty Publications

Real-estate websites make it easy to find and access information about a home. Information on property value, square footage, number of rooms, quality of schools, crime rates, and more is readily available. Some of these platforms have begun integrating climate-related risks in generic ways. However, this information provides limited if any actionable value and is unlikely to guide people’s decision-making on buying or renting a home, deciding where to vacation, or investing in a property. Making residents aware of the natural hazard risks to which their homes may be exposed is an important component of making communities more resilient. Both …

The Impact Of Seasonal Hydrological Disturbances On The Presence And Formation Of Toxic Cyanobacteria Blooms In Coastal Louisiana, Courtney Nicole Hammond, Sibel Bargu, Caitlin R.R. Turner, Matthew Hiatt, John R. White

Faculty Publications

Estuaries in the Gulf, especially Lake Pontchartrain Estuary in southeastern Louisiana, USA, are experiencing significant changes due to climate change and coastal restoration efforts. Lake Pontchartrain Estuary receives nutrient-rich Mississippi River water through a controlled diversion called Bonnet Carré Spillway (BCS), which has been associated with toxic cyanobacterial blooms (cyanoHABs). This study examines the seasonal factors influencing cyanoHABs in the Lake Pontchartrain Estuary when the BCS is closed, addressing gaps in the understanding of HABs related to other physical drivers. Field samples collected in 2021, during the closure of the spillway, revealed significant evidence of seasonal variations in cyanoHAB formation. …