Digital Commons Network^™

Biob 109n.50: Montana Ecosystems - Online, Gregory D. Peters

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Chmy 123.Vh1: Introduction To Organic And Biochemistry, Julia Michelle Kotler

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ptrm 141y.01: National Parks And American Culture, Alejandrina R. Ocanas

University of Montana Course Syllabi, 2021-2025

No abstract provided.

A Neutrosophic Logic Ruled Based Machine Learning Approaches For Chronic Kidney Disease Risk Prediction, Bhabani S.Mohanty, Krishna Priya R, Liya Alias, R. Vijaya Kumar Reddy, Prasanta Kumar Raut, Samson Isaac, Manibharathi D, C. Saravanakumar, Nihar Ranjan Panda, Said Broumi

Neutrosophic Sets and Systems

Chronic kidney disease (CKD) represents a significant global health challenge in society, and early detection of risk is essential for on-time treatment and intervention. This research suggests a novel machine-learning technique to create a reliable and accurate CKD risk prediction model by combining neutrosophic logic with various classification algorithms. We use neutrosophic logic to address the inherent imprecision and uncertainty in medical data, resulting in a more realistic portrayal of real-world scenarios. We measure the effectiveness of the proposed neutrosophic logic-based models using various metrics, including precision, specificity, and sensitivity. The results show that the neutrosophic logic method is better …

Analytical Solutions Of Heat Transfer Model In Two-Dimensional Case Of Neutrosophic Fredholm Integro-Di Erential Equations, Amer Darweesh, Kamel Al- Khaled, Marwan Alquran, Adel Almalki, Sohad Al-Omari

Neutrosophic Sets and Systems

This article uses the fractional residual power series (FRPS) method to solve a linear neutrosophic fractional integro-di erential equation in two dimensions. In what context does the term fractional derivative appeared, we presented the modi ed fractional power series method, a new technique that uses fractional power series expansion to approximate neutrosophic fractional integro-di erential equations. A modi ed new method has been formulated, which is an improvement on the RPS, named as Modi ed Fractional Power Series Method (MFPSM), to solve the same problem under investigation. Novel results associated with the rate of convergent and error order of the …

Bayesian Population Pharmacokinetic Modeling Of Ondansetron For Neonatal Opioid Withdrawal Syndrome, Kevin Lam, John Mondick, Gary Peltz, Manhong Wu, Walter Kraft

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Ondansetron is an anti-emetic 5-HT3 receptor antagonist being investigated for treating neonatal opioid withdrawal syndrome (NOWS). Sparse PK data were analyzed from a multicenter, double-blind clinical trial with 98 mother/neonate dyads. Pregnant women with opioid use disorder were randomized to receive either placebo or ondansetron 8 mg intravenously within 4 h of delivery. Neonates born to mothers who were randomized to ondansetron received 0.07 mg/kg orally once every 24 h for up to five doses. Using current PK data, model parameters from a two-compartmental structural model from the literature (i.e., a priori model) were updated with the Metropolis-Hastings Markov-chain Monte …

Anty 101h.80: Anthropology And The Human Experience - Honors, David Garret Kerr

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Chmy 121n.00: Introduction To General Chemistry, Eric A. John

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Neur 110n.01: Introduction To Brain Diseases, Beverly J. Piggot

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Membrane Filtration Of Nanoscale Biomaterials: Model System And Membrane Performance Evaluation For Aav2 Viral Vector Clarification And Recovery, Mara Leach, Kearstin Edmonds, Emily Ingram, Rebecca Dutch, Sumith R. Wickramasinghe, Malgorzata Chwatko, Dibakar Bhattacharyya

Chemical Engineering Faculty Publications and Presentations

The growing demand for viral vectors as nanoscale therapeutic agents in gene therapy necessitates efficient and scalable purification methods. This study examined the role of nanoscale biomaterials in optimizing viral vector clarification through a model system mimicking real AAV2 crude harvest material. Using lysed HEK293 cells and silica nanoparticles (20 nm) as surrogates for AAV2 crude harvest, we evaluated primary (depth filters) and secondary (membrane-based) filtration processes under different process parameters and solution conditions. These filtration systems were then assessed for their ability to recover nanoscale viral vectors while reducing DNA (without the need for endonuclease treatment), protein, and turbidity. …

Magnetic Nanoparticles: Advances In Synthesis, Sensing, And Theragnostic Applications, Adeyemi O. Adeeyo, Mercy A. Alabi, Joshua A. Oyetade, Thabo T.I. Nkambule, Bhekie B. Mamba, Adewale O. Oladipo, Rachel Makungo, Titus A.M. Msagati

All Rsif Scholars' Publications

The synthesis of magnetic nanoparticles (MNPs) via the chemical, biological, and physical routes has been reported on along with advantages and attendant limitations. This study focuses on the sensing and emerging theragnostic applications of this category of nanoparticles (NPs) in clinical sciences by unveiling the unique performance of these NPs in the biological sensing of bacteria and nucleotide sequencing. Also, in terms of medicine and clinical science, this review analyzes the emerging theragnostic applications of NPs in drug delivery, bone tissue engineering, deep brain stimulation, therapeutic hyperthermia, tumor detection, magnetic imaging and cell tracking, lymph node visualization, blood purification, and …

Prediction Models Of Basal Energy Expenditure In Children And Adolescents Across The Bmi Spectrum Based On Room Calorimetry: A Cross-Sectional Cohort Study, Maurice Puyau, Roman Shypailo, Nancy F Butte, Salma Musaad, Fida Bacha

Children’s Nutrition Research Center Staff Publications

Background: Existing equations for prediction of basal energy expenditure (BEE) may not be accurate in children with overweight or obesity (OW/OB).

Objectives: We aimed to develop BEE prediction equations applicable to children and adolescents across a wide BMI spectrum using gold standard room calorimetry.

Methods: We measured weight, height, waist and hip circumferences, body composition (DXA), and BEE (whole room calorimetry) in a cross-sectional cohort of 1155 healthy children, 5-19 years of age. 67% of the males and 51% of the females were classified as OW/OB. We applied multiple linear regression analyses to develop BEE prediction models for each sex. …

Association Between Maternal Stress And Child Sleep Quality: A Nationwide Echo Prospective Cohort Study, Sarah Dee Geiger, Aruna Chandran, Marie L Churchill, Maxwell Mansolf, Cai Zhang, Salma Musaad, Courtney K Blackwell, Stephanie M Eick, Dana E Goin, Susan Korrick, Akram Alshawabkeh, Patricia A Brennan, Carrie V Breton, Jose F Cordero, Sean Deoni, Viren D'Sa, Anne L Dunlop, Amy J Elliott, Assiamira Ferrara, Arlene Keddie, Monique Lebourgeois, Kaja Z Lewinn, Daphne Koinis-Mitchell, Maristella Lucchini, Sara S Nozadi, Thomas O'Connor, Yeyi Zhu, Emily Zimmerman, Susan L Schantz

Children’s Nutrition Research Center Staff Publications

Background: Childhood sleep quality is associated with physical, cognitive, and behavioral health and predicts later sleep quality; it has many determinants, including developmental exposures.

Objectives: To examine associations between maternal stress during pregnancy and childhood sleep quality and determine whether postnatal stress mediates the association.

Method: Data from the Environmental Influences on Child Health Outcomes cohort were used. Perceived Stress Scale (PSS) T-scores were the exposure measure. Outcome measures were preschool Child Behavior Checklist (CBCL) sleep syndrome scale and Patient-Reported Outcomes Measurement Information System Sleep Disturbance Parent Proxy short form 4a (PSD4a) T-scores at ages 4-8 years. Linear mixed-effects regression …

Childhood Religious Participation As Mediator For Posttraumatic Symptoms And A Joyful Disposition In Adulthood, Kara S. Mccoy

Walden Dissertations and Doctoral Studies

Individuals who have experienced trauma may have varying life experience outcomes based on trauma histories and other factors. Little to no study has been done to determine whether childhood religious involvement can be a mediating factor. The purpose of this quantitative study was to test if any potential mediating effects exist between childhood religious attendance, the presence of joyfulness in life, and adult posttraumatic symptoms. The theoretical framework utilized in this study was Kenneth Pargament’s theory of religious coping. Data were collected in a secure fashion utilizing Survey Monkey, and all participants voluntarily answered questions that utilized the short posttraumatic …

Relationship Between Parental Neglect, Socioeconomic Status, And Aggression In Adolescents, Chemarin Eve Boyd

Walden Dissertations and Doctoral Studies

Aggressive behavior among adolescents poses significant challenges for families, educators, and communities, often stemming from complex interactions between parental behavior and environmental factors. This quantitative nonexperimental study examined the relationship between parental neglect, socioeconomic status (SES), and adolescent aggression, guided by the parental acceptance-rejection theory. Data were collected from 250 parents of adolescents age 12-18 divided into two groups: those reporting no to low levels of aggression and those reporting moderate to high levels. Binary logistic regression was employed to predict the likelihood of adolescent aggression based on parental neglect (categorical) and SES (scale). The results demonstrated that parental neglect …

The Role Of Marine Co2 Removal In Combating Climate Change, Sarah Vican, Meghan Gavin, Wil Burns, Douglas Edwards, Romany M. Webb

Sabin Center for Climate Change Law

Combating climate change requires not only rapid reduction of greenhouse gas emissions, but also removal of significant amounts of carbon dioxide (CO2) from the atmosphere. CO2 removal (CDR) comes in many different forms, but climate scientists and policymakers are focusing on the potentially important role of large-scale use of emerging ocean-based techniques, often referred to as marine CDR (mCDR). In the United States, mCDR in domestic waters is governed by a patchwork of laws and regulations. There are also major uncertainties concerning regulation of mCDR in the open ocean, where international treaty regimes have struggled to develop coherent rules. On …

Reducing Pollution From Concentrated Animal Feeding Operations By Enforcing National Pollutant Discharge Elimination System Permit Requirements Under The Clean Water Act, Shelby White

Colorado Environmental Law Journal

No abstract provided.

Challenges And Opportunities For Data Integration To Improve Estimation Of Migratory Connectivity, Jeffrey A. Hostetler, Emily B. Cohen, Christen M. Bossu, Amy L. Scarpignato, Kristen Ruegg, Andrea Contina, Clark S. Rushing, Michael T. Hallworth

School of Integrative Biological & Chemical Sciences Faculty Publications

1. Understanding migratory connectivity, or the linkage of populations between seasons, is critical for effective conservation and management of migratory wildlife. A growing number of tools are available for understanding where migratory individuals and populations occur throughout the annual cycle. Integration of the diverse measures of migratory movements can help elucidate migratory connectivity patterns with methodology that accounts for differences in sampling design, directionality, effort, precision and bias inherent to each data type.
2. The R package MigConnectivity was developed to estimate population-specific connectivity and the range-wide strength of those connections. New functions allow users to integrate intrinsic markers, tracking and long-distance …

Six-Month Follow-Up Comparing Ait And Eft In The Reduction Of Negative Emotions Associated With A Past Memory, Gregory Brown, Kavita Batra, Emily Dorin, Andrew Han, Arianna Palermini, Robert Sottile, Sherine Khanbijian

Psychiatry & Behavioral Health Faculty Research

The field of Energy Psychology [EP] has amassed hundreds published research studies over its thirty year history which includes both systematic review and meta-analysis level data. These have consistently demonstrated significant effect sizes equivalent to EMDR and trauma based CBT (Church et al., 2022; Feinstein, 2021). Energy Psychology Techniques typically include an energetic component, an emotional component, a somatic component, focus upon a specific memory, which lead to automatic secondary cognitive shifts. Memory Reconsolidation may be a primary psycho-biological explanation for effectiveness. Emotional Freedom Technique [EFT] is the most studied EP technique to date, and considered an evidenced based treatment …

Hydrolysis Of The Acetyl-Coa Allosteric Activator By Staphylococcus Aureus Pyruvate Carboxylase, Amanda J. Laseke, Jeremy R. Lohman, Martin St. Maurice

Biological Sciences Faculty Research and Publications

Pyruvate carboxylase (PC) catalyzes the carboxylation of pyruvate to oxaloacetate which serves as an important anaplerotic reaction to replenish citric acid cycle intermediates. In most organisms, the PC-catalyzed reaction is allosterically activated by acetyl-coenzyme A. It has previously been reported that vertebrate PC can catalyze the hydrolysis of acetyl-CoA, offering a potential means for the enzyme to attenuate its allosteric activation. However, in the years since this initial report, there has been no further investigation of this phenomenon. The allosteric binding site for acetyl-CoA is now well characterized, enabling more detailed studies on acetyl-CoA hydrolysis at the allosteric site. Here, …

Attenuation Of Vitamin E On Haloxyfop-R-Methyl Ester-Induced Hepatic Oxidative Stress In Orally Exposed Rats., Omolara D. Falodun

STEM for Success Resources

No abstract provided.

When Anti-Fraud Laws Become A Barrier To Computer Science Research, Madelyne Xiao, Andrew Sellars, Sarah Scheffler

Faculty Scholarship

Computer science research sometimes brushes with the law, from red-team exercises that probe the boundaries of authentication mechanisms, to AI research processing copyrighted material, to platform research measuring the behavior of algorithms and users. U.S.-based computer security research is no stranger to the Computer Fraud and Abuse Act (CFAA) and the Digital Millennium Copyright Act (DMCA) in a relationship that is still evolving through case law, research practices, changing policies, and legislation

Amid the landscape computer scientists, lawyers, and policymakers have learned to navigate, anti-fraud laws are a surprisingly under-examined challenge for computer science research. Fraud brings separate issues that …

Proving The Future In Criminal Cases, Christopher Slobogin

Vanderbilt Law School Faculty Publications

Expert opinion about dangerousness—the risk of reoffending—is commonly introduced at sentencing, criminal commitment proceedings, and some types of pretrial detention hearings. This Essay argues that the rules governing the admissibility of scientific evidence should apply to this testimony and that, on that assumption, such evidence must be (1) “material” (logically relevant, empirically generalizable, and epistemologically germane), (2) “probative” (a measure of accuracy, which is more stringent when the evidence is from an expert), (3) helpful to the factfinder (through promoting “incremental validity”), and (4) presented in a non-prejudicial manner (i.e., in a way that minimizes the possibility it will be …

Characterizing Prodrome (Premonitory Phase) In Migraine: Results From The Prodrome Trial Screening Period, Todd Schwedt, Richard Lipton, Peter Goadsby, Chia-Chun Chiang, Brad Klein, Cory Hussar, Chengcheng Liu, Sung Yun Yu, Michelle Finnegan, Joel Trugman

College of Nursing Faculty Papers & Presentations

BACKGROUND AND OBJECTIVE: Limited data are available describing the frequency, severity, and consistency of prodromal symptoms followed by headache. This analysis of the PRODROME trial screening period characterized prodromal symptoms in people with migraine, including the most common symptoms and their severity, and the frequency and consistency with which prodromal symptoms were followed by headache.

METHODS: PRODROME was a multicenter, randomized, double-blind, placebo-controlled, crossover trial conducted in the United States that enrolled adults with 2-8 migraine attacks per month who stated they could identify prodromal symptoms that were reliably followed by a headache. The trial included a 60-day screening period …

Bioh 447.01: Genes And Development Lab, Ekaterina Voronina

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Bioo 335.04: Rocky Mountain Flora Lab, Evan Stark-Dykema

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Biob 375.01: General Genetics, Sarah J. Certel

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Biob 491.01: Watershed Science Education & Practice, Dalit Guscio

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Bioe 447.01: Ecosystem Ecology, Benjamin P. Colman

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Biomanipulation, Laura K. Donohue

Georgetown Law Faculty Publications and Other Works

Scientific and technological advances in the latter part of the twentieth century transformed the field of biometrics. Carleton Simon, for instance, first postulated using retinal vasculature for biometric identification in 1935, but it was not until forty years later that an Eyedentify patent brought the idea to fruition. In 1937, John Henry Wigmore anticipated using oscilloscopes to identify individuals by speech patterns. Decades later, digitization and speech processors made voiceprint identification possible. In the 1970s, biological discoveries similarly led to the development of deoxyribonucleic acid (DNA) sequencing. And while Alphonse Bertillon in the late nineteenth century postulated iris distinctions, it …