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Brief Of Amici Curiae Scholars For The Advancement Of Children's Constitutional Rights And Students Engaged In Advancing Texas In Support Of Respondents, Mahmoud V. Taylor, U.S. Supreme Court (No. 24-297), Tanya Washington, Jeremiah Chin, Sarah Medina Camiscoli, Travis F. Chance, Amalia Y. Sax-Bolder, Catherine E. Smith

Court Briefs

Amici are members of Students Engaged in Advancing Texas and United States legal scholars of children and the law, education law, family law, and anti-discrimination law.

Students Engaged in Advancing Texas is a nonprofit organization founded by young people to develop civic leadership and belonging and represents students of various faiths and identities who have an interest in the outcome of this case.

Amici draw this Court’s attention to the constitutional harms that public school students and LGBTQ+ students and students with LGBTQ+ parents would bear should the Court grant Petitioners’ injunctive relief.

Hdac5 Enzymatic Activity Regulates Scn4b Expression To Control Relapse-Like Cocaine Seeking, Daniel J. Wood

MUSC Theses and Dissertations

Substance Use Disorder (SUD) is a relapsing disorder characterized by repeated seeking and use of psychoactive substances despite negative consequences to the individual. Epigenetic changes within the medium spiny neurons (MSNs) of the nucleus accumbens (NAc) are thought to underly the lasting propensity to relapse in SUD. The epigenetic enzyme histone deacetylase 5 (HDAC5) in NAc MSNs limits the formation of reward-cue associations in rodent models of drug seeking, but not sucrose seeking, leading to decreased relapse-like behavior. However, whether HDAC5 reduces drug seeking behavior through its own deacetylase activity or through the recruitment of co-repressors is unknown. Furthermore, these …

The College Voice, Vol. 62, No. 8 [April 9, 2025], Connecticut College

2024-2025

No abstract provided.

What Is A Nation? Colonial Legacies, Identity, And Reclaiming In Métisse Autobiographical Narratives – A Case Study Of Sugar And Slate And Garçon Manqué, Thaïs Maëlle Autin

Foreign Languages & Literatures ETDs

This thesis examines the question of national belonging in autobiographical narratives of second-generation immigrant métisse women. I study the similar aesthetic manner in which individuals with different regional and cultural influences grapple with concepts of identity, gender, racism, exile, and negotiation, and the way in which the authors anchor themselves in a broader familial and national heritage. I argue that such an enterprise can be understood as part of the alternative heritage wave, based on Andrew Higson’s theory. The texts put in question traditional understandings of nation. Doing so opens the possibility of engaging in a dialogue that expands the …

Brief Of Amici Curiae Scholars For The Advancement Of Children’S Constitutional Rights And Students Engaged In Advancing Texas In Support Of Respondents: Mahmoud V. Taylor, Catherine E. Smith, Tanya Washington, Jeremiah Chin, Sarah Medina Camiscoli, Travis F. Chance

Scholarly Articles

Amici are members of Students Engaged in Advancing Texas and United States legal scholars of children and the law, education law, family law, and anti-discrimination law.

Students Engaged in Advancing Texas is a nonprofit organization founded by young people to develop civic leadership and belonging and represents students of various faiths and identities who have an interest in the outcome of this case.

Amici draw this Court’s attention to the constitutional harms that public school students and LGBTQ+ students and students with LGBTQ+ parents would bear should the Court grant Petitioners’ injunctive relief.

Prevalence Of Glucose 6-Phosphate Dehydrogenase Deficiency Among Indian Populations: A Systematic Review, Sudipta Ghosh

Human Biology Open Access Pre-Prints

Glucose 6-Phosphate Dehydrogenase (G6PD) deficiency is the most prevalent enzyme deficiency of human erythrocytes affecting more than 500 million people globally. G6PD deficiency is the most common hemolytic X-linked genetic disease, which shows a higher prevalence rate in the malarial endemic population. This review paper aims to examine the overall frequency of G6PD deficiency in the Indian population using systemic review, with a special emphasis on the differential prevalence rate across the populations. PubMed, Google Scholar, and Science Direct databases were searched to examine the scientific studies focusing on the prevalence of G6PD deficiency amongst the Indian populations. A total …

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Bio-Inspired Highest Lift-To-Drag-Ratio Fin Shape And Angle For Maximum Surfboard Stability: Flow Around Fish Fins, Megan S. Macneill, Brian Barkdoll

Michigan Tech Publications

Wave surfing is a multi-billion dollar industry involving both maneuverability and speed, yet little research has been performed regarding the highest lift-to-drag-ratio fin shape for these competing qualities. Numerical modeling and laboratory experiments were performed here to identify a bio-inspired fin shape that maximized lateral stability and minimized drag forces, in order to increase surfing maneuverability. Nine fins based on dorsal fins of real fish were tested. Both the CFD and laboratory experiments confirmed that the fin of the same shape as that of the Short-Finned Pilot Whale at an angle of attack of 10° had the greatest lift-to-drag ratios. …

Mindful Lawyering: Incorporating Mindfulness Into The American Bar Association’S Model Rules Of Professional Conduct, Lyda Creus Molanphy

St. Mary's Journal on Legal Malpractice & Ethics

No abstract provided.

Development Of Scalable Coastal And Offshore Kelp Farming For Marine Biomass Production, Michael Stekoll, Scott Lindell, Clifford A. Goudey, Hauke L. Kite-Powell, David Bailey, Kendall Barbery, Loretta Roberson, Tamsen Peeples, Nicholas Mangini, Alf Pryor, Alexandra Meyer, Charles Yarish

Faculty, Staff, and Students

The US DOE/ARPA-E MARINER program funded a 4-year project to determine an optimal way to grow kelps in large, nearshore and offshore arrays for the eventual purpose of biofuel production with the goal of keeping the cost below $80 USD per dry metric ton of kelp. This project specifically looked at how Saccharina latissima can be grown in the Gulf of Alaska to reach that goal. There were three major aspects of the research: (1) optimize nursery production and seeding lines for outplanting; (2) design an economical, modular outplanting structure; and (3) develop methods to efficiently harvest the product. Farm …

Effects Of Wetting Events On Mass Timber Surface Microbial Communities And Voc Emissions: Implications For Building Operation And Occupant Well-Being, Gwynne Á. Mhuireach, Susan Collins, Leslie Dietz, Patrick Finn Horve, Aurélie Laguerre, Dale Northcutt, Jason Stenson, Kevin Van Den Wymelenberg, Elliott Gall, Mark Fretz

Mechanical and Materials Engineering Faculty Publications and Presentations

IntroductionHumans have used wood as a construction material throughout history. Currently, mass timber products, such as cross-laminated timber (CLT), are becoming more popular as a structural material, since they are renewable and have a lower carbon footprint than concrete or steel. Nonetheless, some building types, such as healthcare, veterinary, and food manufacturing, avoid using structural mass timber due to concerns about microbial growth in the event of wetting. One solution is to use protective coatings on mass timber products to increase moisture resistance, although the coatings themselves may generate concerns about volatile organic compound (VOC) emissions. Natural uncoated wood also …

The Parthenon, April 09, 2025, Sarah Davis, Baylee Parsons, Kaitlyn Fleming, Nate Harrah, Caden Adkins, Scott Price, Ella Bumgardner, Wade Sullivan

The Parthenon

No abstract provided.

Greenhouse Gas Emissions From Flood-Irrigated Rice As Affected By Phosphorus Fertilizer Source, Chandler M. Arel, Kristofor R. Brye, Diego Della Lunga, Trenton L. Roberts, Richard Adams

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Research into alternative phosphorus (P) fertilizer sources that may be able to supplement P resources is necessary. Struvite (MgNH4PO4 · 6H2O) can be made by removing excess nutrients from waste sources and may reduce greenhouse gas (GHG) emissions from cropping systems. This study sought to quantify GHG [i.e., methane (CH4), nitrous oxide (N2O), and carbon dioxide (CO2)] fluxes, season-long emissions, and net GHG emissions from chemically precipitated struvite (CPST) and synthetic and real-wastewater-derived electrochemically precipitated struvite (ECST) compared to monoammonium phosphate (MAP) and an unamended control (UC) from flood-irrigated rice (Oryza sativa) grown in P-deficient, silt loam soil in a …

Electric Field Profiles Under High Voltage Overhead Transmission Lines With Under-Build Distribution Circuit, Aminu Haruna

Electrical Engineering Theses

The increasing use of underbuilt lines in recent transmission projects alters electric field profile under transmission lines. By assessing electric field intensity in these transmission and distribution network configurations, the study identifies regions with high electric fields that may exceed standard exposure limits, posing potential risks. This work employs the charge simulation method and the method of imaging to analyze electric fields beneath transmission lines with underbuilt distribution networks. Key objectives include calculating the electric fields at 1 meter above ground, and evaluating the field at conductor surfaces. The study considers transmission line voltages of 69kV, 161kV, 220kV, 345kV and …

The Association Of Sleep Quality And Depression On Having Three Vs. All Five Diagnostic Criteria Of Metabolic Syndrome, Nina Pollard

Walden Dissertations and Doctoral Studies

Metabolic syndrome is increasing in prevalence in the United States. To be diagnosed, three of the five diagnostic criteria must be met. There is a higher risk of metabolic syndrome due to lifestyle and social factors, with increased criteria occurring as an individual has unmet social determinants of health. This quantitative quasi-experimental/quasi-comparative study examined the association between education level, with sleep quality and depression as moderators, on a diagnosis of metabolic syndrome with all five criteria versus three criteria using a binary logistic regression while controlling for age, race, gender, income, employment, and marital status. Bronfenbrenner’s social ecological theory served …

Book Review: Wombs Of Empire: Population Discourse And Biopolitics In Modern Japan, By Sujin Lee, Bonnie Tilland

Asia Pacific Perspectives

No abstract provided.

Association Of Clonal Hematopoiesis Of Indeterminate Potential With Cardiovascular Events In Patients With Ckd, Yang Pan, Caitlyn Vlasschaert, Varun Rao, Elvis A Akwo, James E Hixson, Md Mesbah Uddin, Zhi Yu, Do-Kyun Kim, Alexander Bick, Bryan Kestenbaum, Michael Chong, Guillaume Paré, Michael Rauh, Adeera Levin, James P Lash, Manjula Kurella Tamura, Debbie L Cohen, Jiang He, Lee Hamm, Rajat Deo, Zeenat Bhat, Panduranga Rao, Dawei Xie, Pradeep Natarajan, Tanika N Kelly, Cassianne Robinson-Cohen, Matthew B Lanktree

Faculty, Staff and Student Publications

Key Points:

1. In patients with CKD, non-DNMT3A clonal hematopoiesis of indeterminate potential (CHIP) was associated with higher risk of cardiovascular events.

2. There was no significant difference in the CHIP–cardiovascular disease association based on baseline eGFR, diabetes status, or race.

3. The protective effect of IL6R p.Asp358Ala on non-DNMT3A CHIP cardiovascular risk was similar to the general population.

Background: Patients with CKD are at higher risk of cardiovascular disease. Clonal hematopoiesis of indeterminate potential (CHIP) has been associated with cardiovascular disease in the general population, with a causal role observed in animal models. In the general population, the effect of …

Can Endothelin-1 Help Address The Diagnostic And Prognostic Challenges In Multimorbid Acute Heart Failure Patients?, Bianca-Ana Dmour, Minerva Codruta Badescu, Cristina Tuchiluș, Corina Maria Cianga, Daniela Constantinescu, Nicoleta Dima, Ștefania Teodora Duca, Awad Dmour, Alexandru Dan Costache, Maria-Ruxandra Cepoi, Adrian Crișan, Sabina Andreea Leancă, Cătălin Loghin, Ionela-Lăcrămioara Șerban, Irina Iuliana Costache-Enache

Faculty, Staff and Student Publications

The management of acute heart failure (AHF) is becoming increasingly complex, especially in patients with multiple comorbidities. Endothelin-1 (ET-1), a vasoconstrictive peptide, is an important mediator of neurohormonal activation, endothelial dysfunction, and cardiac remodeling-key processes involved in the pathogenesis of AHF. The aim of our study was to evaluate the diagnostic and prognostic performance of ET-1 in multimorbid AHF patients, compared to established markers such as amino terminal pro B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin I (hs-cTnI). We conducted a single-center prospective study including 76 patients; 54 with AHF and 22 serving as controls. Upon admission, all patients …

Cell Type-Specific Multi-Omics Analysis Of Cocaine Use Disorder In The Human Caudate Nucleus, Lea Zillich, Annasara Artioli, Veronika Pohořalá, Eric Zillich, Laura Stertz, Hanna Belschner, Ammar Jabali, Josef Frank, Fabian Streit, Diana Avetyan, Maja P Völker, Svenja Müller, Anita C Hansson, Thomas D Meyer, Marcella Rietschel, Julia Ladewig, Rainer Spanagel, Ana M M Oliveira, Consuelo Walss-Bass, Rick E Bernardi, Philipp Koch, Stephanie H Witt

Faculty, Staff and Student Publications

Structural and functional alterations in the brain's reward circuitry are present in cocaine use disorder (CocUD), but their molecular underpinnings remain unclear. To investigate these mechanisms, we performed single-nuclei multiome profiling on postmortem caudate nucleus tissue from six individuals with CocUD and eight controls. We profiled 30,030 nuclei, identifying 13 cell types including D1- and D2-medium spiny neurons (MSNs) and glial cells. We observed 1485 differentially regulated genes and 10,342 differentially accessible peaks, with alterations in MSNs and astrocytes related to neurotransmitter activity and synapse organization. Gene regulatory network analysis identified transcription factors including ZEB1 as exhibiting distinct CocUD-specific subclusters, …

Geographic Divergence Of Methicillin-Resistant Staphylococcus Aureus St5-Scc Mec I In The Aftermath Of A Major Earthquake And Tsunami: Impact Of A Plasmid Harboring Heavy Metal Resistance Genes, Jose R W Martínez, Manuel Alcalde-Rico, Estefanía Jara-Videla, Jinnethe Reyes, Lina P Carvajal, Sandra Rincon, Rafael Ríos, Lorena Diaz, Ana Quesille-Villalobos, Roberto Riquelme-Neira, Lina Rivas, Ahmed M Moustafa, Blake Hanson, Eduardo A Undurraga, Jorge Olivares-Pacheco, Patricia García, Rafael Araos, Paul J Planet, César A Arias, Jose M Munita

Faculty, Staff and Student Publications

Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health menace. The global spread of MRSA is characterized by successive waves of epidemic clones dominating specific geographical regions. The acquisition of genes encoding resistance to heavy metals (HMRGs) is thought to be a key feature in the geographic divergence of MRSA. However, the cause-effect relationship between the presence of HMRGs and the divergence of MRSA clones remains to be clarified. In this study, we assessed the role that HMRGs may have played in the evolutionary divergence of the MRSA ST5-SCCmecI lineage in Latin America. We conducted a genomic characterization …

An In Vivo Microscopy Dataset For The Characterization Of Leukocyte Death, Alain Pulfer, Diego Ulisse Pizzagalli, Miguel Palomino Segura, Nina Germic, Tommaso Virgilio, Mauro Di Pilato, Pau Carrillo Barbera, Elisa Palladino, Paola Antonello, Marcus Thelen, Hans-Uwe Simon, Rolf Krause, Santiago F Gonzalez

Faculty, Staff and Student Publications

Recent advancements in intravital microscopy have enabled the study of cell death in vivo under various experimental conditions, such as infection and cancer. However, the limited throughput of this technology, together with a lack of openly accessible datasets, affects the development of algorithms for the automatic detection and characterization of cell death, which in turn require the integration of extensive and curated datasets. To address these needs, we present a curated dataset of microscopy videos depicting the death of neutrophils, eosinophils, and dendritic cells, acquired in the spleen and in the lymph node of mice under inflammatory conditions. The dataset …

Pilrα Sustains Microglial Capacity To Process Myelin In A Mouse Model Of Demyelination, Kent Lin

Arts & Sciences Graduate Student Theses and Dissertations

Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, and neurodegeneration. Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in AD pathogenesis by containing the spreading of Aβ plaques. Genetic studies have associated a variant of the receptor Paired Immunoglobulin-like Type 2 Receptor Alpha (PILRα) with reduced risk for AD. PILRα is a receptor found on myeloid cells, such as microglia, that binds to endogenous cell surface glycoproteins and sends inhibitory signals within the cell. Additionally, it serves as an entry receptor for Herpes Simplex Virus 1. To elucidate the role …

Eco-Genotoxicology: A Personal Reflection, Awadhesh N. Jha

School of Biological and Marine Sciences

This reflective commentary provides a personal viewpoint of developments, over the last 3 decades, in the relatively new, multidisciplinary field of ‘eco-genotoxicology,’ also called ‘genetic ecotoxicology’. It aims to outline the scope of the subject area in relation to the historical development of the discipline, critically categorising accomplishments made, taking into account the available information. It also recognises limitations of the existing information and difficulties encountered in this challenging field. Where appropriate, the article makes comparisons to the advances made in human genetic toxicology and radiation biology. The article critically covers the applications of prevailing and emerging tools being used …

A Review On Detection Of Drought Stress In Tea Plants Through Morphological, Physiological, And Biochemical Approaches, Intan Ratna Dewi Anjarsari, Erni Suminar, Nabila Ragil Wiharti

Jurnal Kultivasi

Tea plants (Camellia sinensis) are important commodities with high economic value, but their production is greatly affected by environmental stresses such as drought and extreme temperatures. Global warming in recent years has led to extreme weather events and an increase in the earth's temperature, which also causes drought. Drought stress is one of the most significant abiotic factors affecting crop productivity. However, despite significant progress, there remains a notable gap in research, particularly the lack of integrated studies that combine morphological, physiological, and biochemical indicators for early and precise detection of drought stress in tea plants. To identify and mitigate …

Cluster Analysis To Explore Morphological Variation Of Banana (Musa Spp.): A Case Study In Jember And Lumajang, East Java, Indonesia, Halimatus Sa'diyah, Vega Kartika Sari, Riza Yuli Rusdiana, Achmad Chaqiqotul Khofi

Jurnal Kultivasi

Banana (Musa spp.) is an important horticultural plant with a high variety in Indonesia; yet, knowledge on the morphological characteristics of indigenous bananas in East Java remains inadequate. This research aims to identify the variation and classify banana cultivars in East Java based on morphological character. The exploration was conducted using the accidental sampling method. The observations include 15 qualitative and 9 quantitative characters. Descriptive statistics were used to evaluate the data, followed by cluster analysis using the average linkage method and Euclidean distance. The exploration resulted in 15 banana cultivars with varying morphology. The cluster analysis shows banana cultivars …

Agronomic Performance And Stability Of Padjadjaran Hybrid Maize In Different Agroecosystems, Farhan Fadhillah, Fiky Yulianto Wicaksono, Yuyun Yuwariah, Dedi Ruswandi

Jurnal Kultivasi

The development of high-yielding hybrid maize is a strategic step to address global food demand amidst climate change. This study evaluates the agronomic performance of 14 maize genotypes—10 newly developed F1 hybrids and 4 commercial checks—under two planting densities (95,000 and 55,000 plants/ha) across three agroecosystems (lowland, midland, and highland). The objectives were to identify superior and adaptive genotypes and analyze genotype × environment interactions using AMMI and GGE biplot methods. Genotype G12 exhibited the highest yield (338.4 g/plant) at high density, especially in the highland, but showed poor stability. In contrast, G5 demonstrated consistent performance and stability across environments. …

Antioxidant Activity (2-2-Diphenil-1-Picrilhydrazil Radical-Scavenging Assay) And Phytochemicals Of Mimosa Invisa Colla And Mimosa Pigra L. Grown At Different Terrestrial Habitats, Irawati Chaniago, Ryan Budi Setiawan, Ardi, Doni Hariandi, Winda Purnama Sari

Jurnal Kultivasi

Giant false sensitive plants (Mimosa invisa Colla) and giant sensitive plants (Mimosa pigra L.) are invasive plant species in the tropics and native to America. They are widely distributed in different ecosystems and soil types. Apart from being considered woody shrub weeds, these plant species can be used as herbal medicine for their antioxidant activities. An experiment to study the antioxidant activities and phytochemicals of M. invisa and M. pigra grown at 200 m from the coastline and close to the riverbank (riparian abandoned land) was carried out from March to November 2023. Weed leaves were collected as purposive randomized …

Understanding Infection, Viral Exacerbation And Respiratory Symptoms At Admission-Longitudinal (Universal) Study: A Prospective Observational Cohort Study Protocol, Universal Study Group, Tommaso Morelli, Martha Purcell, Pedro Rodrigues, Charles Roberts, Olivia Cox, Paul H. Lee, Kerensa Thorne, Alexander Allen, Angelica Cazaly, Jacqueline Nuttall, James Raftery, Gareth Griffiths, Andrew Cook, Nicola White, Neil J. Greening, Matthew Pavitt, James Myerson, Stefan J. Marciniak, Cyrus Daneshvar, Michael G. Crooks, Philip Mitchelmore, James D. Chalmers, Salman Siddiqui, Karl J. Staples, Tristan William Clark, Anna Freeman, Tom Wilkinson, Emma Tilt

Peninsula Medical School

Background Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 pandemic has underscored the urgent need for a deeper understanding of RVIs to improve patient outcomes and develop effective treatment strategies. The Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal Study is an observational study which addresses this need by investigating the heterogeneity of RVIs in hospitalised adults, aiming to identify clinical and biological predictors of adverse outcomes. This study aims to bridge critical knowledge gaps in the clinical course …

Co-Designing A Web-Based And Tablet App To Evaluate Clinical Outcomes Of Early Psychosis Service Users In A Learning Health Care Network: User-Centered Design Workshop And Pilot Study, Kathleen E Burch, Adam B Wilcox, Et Al.

2020-Current year OA Pubs

BACKGROUND: The Early Psychosis Intervention Network of California project, a learning health care network of California early psychosis intervention (EPI) programs, prioritized incorporation of community partner feedback while designing its eHealth app, Beehive. Though eHealth apps can support learning health care network data collection aims, low user acceptance or adoption can pose barriers to successful implementation. Adopting user-centered design (UCD) approaches, such as incorporation of user feedback, prototyping, iterative design, and continuous evaluation, can mitigate these potential barriers.

OBJECTIVE: We aimed to use UCD during development of a data collection and data visualization web-based and tablet app, Beehive, to promote …

Activation Of Endoplasmic Reticulum-Localized Metabotropic Glutamate Receptor 5 (Mglu5) Triggers Calcium Release Distinct From Cell Surface Counterparts In Striatal Neurons, Yuh-Jiin I Jong, Steven K Harmon, Karen L O'Malley

2020-Current year OA Pubs

Metabotropic glutamate receptor 5 (mGlu