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Complex Emotions, Jessica Choe, Lisa K. Lashley, Charles J. Golden Apr 2025

Complex Emotions, Jessica Choe, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Complex emotions are ways in which an individual reacts and respond to complex social situations when encountering people and situations in the social world. Thus, complex emotions are ways of coping and adapting to complex social situations. Complex emotions are mental representations that have been studied on a three-level analysis surrounding the body, mind, and society, which translates to the biological and the evolutionary, the mental and the psychological, and the social and the cultural. This approach has been referred to as the neurocognitive sociology of emotions.


Psychomotor Speed In Old Age, Cheryl Chakranarayan, Nathan C. Weed Apr 2025

Psychomotor Speed In Old Age, Cheryl Chakranarayan, Nathan C. Weed

Essays in Developmental Psychology

Psychomotor ability is defined in terms of the relationship between cognitive functions and motor activities. It plays an important role in acquiring and carrying out a broad range of physical skills and coordinated behaviors, such as playing a sport, or in everyday activities like pouring a glass of milk or applying makeup. Psychomotor speed therefore is the rate at which a certain psychomotor behavior can be carried out. Because of the relevance of psychomotor speed to many areas of personal functioning, it has been extensively studied in a wide variety of applied contexts including sports performance, personnel selection within the …


Detection Of Mthfr C677t Genotyping For Spina Bifida Defects Using Arms-Pcr Technique, Halah Kamal Al-Qazzaz, Zahraa F. Al-Khero, Hameed Husham Hameed Apr 2025

Detection Of Mthfr C677t Genotyping For Spina Bifida Defects Using Arms-Pcr Technique, Halah Kamal Al-Qazzaz, Zahraa F. Al-Khero, Hameed Husham Hameed

Baghdad Science Journal

Neural tube defects (NTDs) are complex structural deformities in newborn infants. These defects are caused by a blend of genetic and environmental factors in the abnormal phenotype. The current study aims to determine the genetic variation polymorphism for methylenetetrahydrofolate reductase (MTHFR) C677T rs180133 genotyping and to detect single nucleotide polymorphisms (SNPs) in a DNA sample of Spinal Bifida (SB) and compare it with control newborn children. Blood samples were collected from newborns (50 children under one year old) (25 cases of spinal bifida (SB) and 25 controls). The DNA was extracted and amplified by the tetra ARMS-PCR technique (Amplification Refractory …


The Dynamic Immune Behavior Of Primary And Metastatic Ovarian Carcinoma, Elaine Stur, Fuduan Peng, Pang-Ning Teng, Emine Bayraktar, Min Hu, Sara Corvigno, David J Brown, Sanghoon Lee, Kathleen N Moore, Nicholas W Bateman, Kathleen M Darcy, George L Maxwell, Thomas P Conrads, Nidhi Sahni, Ignacio Vázquez-García, Sohrab P Shah, Joseph Celestino, Nicole D Fleming, Nicholas E Navin, Linghua Wang, Anil K Sood Apr 2025

The Dynamic Immune Behavior Of Primary And Metastatic Ovarian Carcinoma, Elaine Stur, Fuduan Peng, Pang-Ning Teng, Emine Bayraktar, Min Hu, Sara Corvigno, David J Brown, Sanghoon Lee, Kathleen N Moore, Nicholas W Bateman, Kathleen M Darcy, George L Maxwell, Thomas P Conrads, Nidhi Sahni, Ignacio Vázquez-García, Sohrab P Shah, Joseph Celestino, Nicole D Fleming, Nicholas E Navin, Linghua Wang, Anil K Sood

Faculty, Staff and Student Publications

Patients with high-grade serous ovarian carcinoma (HGSC) are usually diagnosed with advanced-stage disease, and the tumors often have immunosuppressive characteristics. Together, these factors are important for disease progression, drug resistance, and mortality. In this study, we used a combination of single-cell sequencing and spatial transcriptomics to identify the molecular mechanisms that lead to immunosuppression in HGSC. Primary tumors consistently showed a more active immune microenvironment than did omental tumors. In addition, we found that untreated primary tumors were mostly populated by dysfunctional CD4 and CD8 T cells in later stages of differentiation; this, in turn, was correlated with expression changes …


David F. Bjorklund, Rhonda Douglas Brown Apr 2025

David F. Bjorklund, Rhonda Douglas Brown

Essays in Developmental Psychology

David F. Bjorklund is an eminent scholar in the field of developmental psychology.  He was born on June 13, 1949 in Worcester, Massachusetts.  He received his bachelor’s degree cum laude in psychology from the University of Massachusetts, Amherst in 1971.  His graduate degrees include a master’s in psychology from the University of Dayton in 1973 and a doctorate in developmental psychology from the University of North Carolina at Chapel Hill in 1976, as well as a Distinguished Alumnus Award in 2002.  He received an Honorary Doctorate from the University of Bern, Switzerland in 2015.  Bjorklund is currently a Professor of …


Lifespan Perspective, Leila Eikevik Apr 2025

Lifespan Perspective, Leila Eikevik

Essays in Developmental Psychology

Psychologists who study human development have adopted the lifespan perspective, which maintains that important changes occur during every period of development and that these changes must be interpreted in terms of the culture and context in which they occur (Boyd and Bee, 2009). Prior to this understanding, the subject of development was limited to childhood. This view has shifted because it is evident adults continue to experience major life changes and there has been a significant increase in age expectancy. Therefore, all stages of life are equally important. Lifespan development begins at the time of conception and continues up until …


Naïve Theories, Ethan Fleuchaus, Heidi Kloos Apr 2025

Naïve Theories, Ethan Fleuchaus, Heidi Kloos

Essays in Developmental Psychology

While the idea of the mind as a blank slate has long been abandoned, the question of what exactly a “non-blank slate” might look like is still debated. In this entry we discuss the claim that children are equipped with naïve theories—primitive, incomplete, or otherwise ill-formed, but nevertheless systematic, mental representations of cause-effect relations. Other terms that reflect this idea include ‘misconceptions’, ‘naïve beliefs’, ‘prior theories’, ‘alternative conceptions’, or ‘intuitive theories’. Their main characteristic is that they interfere with an open-minded exploration of the surrounding. The unfortunate result of such biased exploration is that children ignore evidence that conflicts with …


Heinz Werner, Ethan Fleuchaus, Katie Cunningham, Heidi Kloos Apr 2025

Heinz Werner, Ethan Fleuchaus, Katie Cunningham, Heidi Kloos

Essays in Developmental Psychology

Heinz Werner (February 11, 1890 – May 14, 1964) was an Austrian psychologist who played an active role in defining the field of developmental psychology at the start of the 20th century. While initially seeking to become a composer and music historian, he changed his mind after listening to a lecture on Immanuel Kant at the University of Vienna. Werner became engrossed in topics of philosophy and psychology (which were combined at the time), and he wrote his dissertation on the psychology of aesthetic experiences. Subsequently he worked at the University of Hamburg, where he published the first edition of …


Patriarchal Violence, Fallon Flowers, Lisa K. Lashley, Charles J. Golden Apr 2025

Patriarchal Violence, Fallon Flowers, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Patriarchal violence has been described as a pattern of behavior by men perpetuated against women in order to maintain control over women and their behavior. Ultimately, it is meant to oppress them; resulting in women being relegated to a lower position in society. The need for men to exert control over women via Patriarchal violence has roots in one’s cultural, societal, and moral beliefs. Such beliefs pertain to what is considered appropriate and what is considered inappropriate in a cultural context.  One of the burgeoning examples of this form of violence against women is the “honor killing”, the killing of …


Apigenin Attenuates Ischemia–Reperfusion-Induced Pulmonary Ferroptosis And Fibrosis By Activating The Nrf2/Ho-1/Gpx4 Axis In Mice, Liang Zhang, Haojie Li, Shichen Xu, Hao Wen, Chaoxiao Yu Apr 2025

Apigenin Attenuates Ischemia–Reperfusion-Induced Pulmonary Ferroptosis And Fibrosis By Activating The Nrf2/Ho-1/Gpx4 Axis In Mice, Liang Zhang, Haojie Li, Shichen Xu, Hao Wen, Chaoxiao Yu

Turkish Journal of Biology

Background/aim: Acute lung injury (ALI) is a major cause of morbidity and mortality after lung ischemia-reperfusion injury (LIRI). In recent years, pulmonary ferroptosis and its associated fibrosis have been recognized as important causes of LIRI. The purpose of this study is to investigate apigenin (APG) as a potential therapeutic target for treating LIRI-induced pulmonary ferroptosis and fibrosis.

Materials and methods: A rat model of LIRI was established and the rats were randomly divided into three groups, a sham group, a LIRI group, and an APG group. The pathological changes of the lung tissue were evaluated using hematoxylin-eosin staining and …


Progression Of Electrophysiological Impairments In Diabetic Cardiomyopathy And Intervention Using Enicostemma Axillare, Victor Arokia Doss, Dharaniyambigai Kuberapandian Apr 2025

Progression Of Electrophysiological Impairments In Diabetic Cardiomyopathy And Intervention Using Enicostemma Axillare, Victor Arokia Doss, Dharaniyambigai Kuberapandian

Turkish Journal of Biology

Earlier studies widely reported advanced ventricular impairments only at the later stages of diabetic cardiomyopathy (DCM). The present study aimed to understand the duration-based early to late stages of cardiac electrophysiological impairments using electrocardiography (ECG) and intervention using Enicostema axillare subsp. littorale. The experimental rats were streptozotocin (SZ)-induced diabetic rats that were administered E. axillare formulations as follows: (1) normal; (2) SZ - 40 mg/kg, single, i.p.); (3) SZ + insulin (2 U/day) + losartan (10 mg/kg); (4) SZ + insulin + losartan + E. axillare decoction (2 mL/day); (5) SZ + E. axillare decoction; (6) SZ + E. axillare …


Resveratrol Modulates Triosephosphate Isomerase And Mineralization In Osteosarcoma Cells: Potential Target For Novel Therapeutic Strategies, Gonca Tuna, Si̇bel Çinar Asa, Eli̇f Ertürk, Yaren Yildiz, Ferda Ari Apr 2025

Resveratrol Modulates Triosephosphate Isomerase And Mineralization In Osteosarcoma Cells: Potential Target For Novel Therapeutic Strategies, Gonca Tuna, Si̇bel Çinar Asa, Eli̇f Ertürk, Yaren Yildiz, Ferda Ari

Turkish Journal of Biology

Background/aim: Osteosarcoma, a primary malignant bone tumor, is challenging to treat due to its aggressive nature and limited therapies. Resveratrol (RES), a natural polyphenol, has potential anticancer properties. Hence, we investigated RES’s impact on osteosarcoma cells, focusing on triosephosphate isomerase (TPI) and related mechanisms.

Materials and methods: RES was applied to osteosarcoma (SaOS-2) and healthy fetal osteoblast (hFOB 1.19) cells for 48 h, and cell viability was measured by SRB assay. The mode of cell death was examined using Hoechst 33342/annexin V/propidium iodide. TPI and methylglyoxal (MG) enzyme levels were determined by ELISA. The effect of RES on …


Knockdown Of Plexin C1 Induces Epithelial-To-Mesenchymal Transition And Confers Resistance To Multikinase Inhibitors In Hepatocellular Carcinoma Cells, Gamze Güngör Topcu, Arzu Aysan, Şevval Di̇k, Mai̇de Şeker, Meli̇ke Bi̇nnur Bahçekapili, Sude Topkaraoğlu, Di̇lek Yavuzer, Tamer Yağci Apr 2025

Knockdown Of Plexin C1 Induces Epithelial-To-Mesenchymal Transition And Confers Resistance To Multikinase Inhibitors In Hepatocellular Carcinoma Cells, Gamze Güngör Topcu, Arzu Aysan, Şevval Di̇k, Mai̇de Şeker, Meli̇ke Bi̇nnur Bahçekapili, Sude Topkaraoğlu, Di̇lek Yavuzer, Tamer Yağci

Turkish Journal of Biology

Background/aim: HCC is a common and lethal malignancy and multi-kinase inhibitors (MKIs) are among the therapeutic options for unresectable cases. However, response rates to MKIs remained variable, necessitating the identification of predictive biomarkers. Plexin C1 (PLXNC1), a receptor involved in cell signaling, has emerged as a potential candidate to regulate tumor responses. This study aims to evaluate the impact of PLXNC1 expression on the sensitivity of HCC cells to MKI therapy.

Materials and methods: shRNA-mediated PLXNC1 knock-down and control clones of HCC cell lines PLC/PRF/5 and Hep3B were generated, and downregulation of PLXNC1 was confirmed using Western blotting. …


Synergetic Effects Of Spironolactone And Dehydro-Cortistatin A On Hiv Suppression, Alexander Lopez Apr 2025

Synergetic Effects Of Spironolactone And Dehydro-Cortistatin A On Hiv Suppression, Alexander Lopez

Harriet L Wilkes Honors College Theses

HIV remains a significant challenge due to its ability to establish latent reservoirs in CD4+ T cells, requiring lifelong antiretroviral therapy (ART). As part of the general effort to find a functional cure for HIV, this study investigated the effects of spironolactone (SP) and dehydro-cortistatin A (dCA) on HIV expression, both individually and in combination, using J-Lat 10.6 cell models. Cells were treated with SP (10 μM), dCA (20 nM), and a combination of both drugs in a longitudinal study, with samples collected at multiple time points. Results indicate that both SP and dCA individually suppress HIV expression compared to …


Modeling Cis/Trans Preferences Of Sn("Acac")2cl2 Complexes, Luke L. Rising, Hanna Sunsdahl, Matthew Burrows, Juan Carlos Feregrino Ponce Apr 2025

Modeling Cis/Trans Preferences Of Sn("Acac")2cl2 Complexes, Luke L. Rising, Hanna Sunsdahl, Matthew Burrows, Juan Carlos Feregrino Ponce

Research & Creative Achievement Day

Tin(IV) complexes bearing two chloride ligands and two symmetric β-diketonate ligands exhibit octahedral geometries. As such, they can theoretically present in two geometric isomer forms, cis and trans. Modeling of isomeric forms of these Sn(IV) complexes with five different β-diketonate ligands has been conducted to identify overall preference as well as to attempt to ascertain any influence the ligand's own electronic properties has on exhibited isomeric preference. Additionally, modeled IR spectra of cis and trans forms were compared to determine the utility of that characterization method in distinguishing these isomers.


Disparities In Women's Healthcare, Allie Sonnleitner Apr 2025

Disparities In Women's Healthcare, Allie Sonnleitner

Research & Creative Achievement Day

Purpose: Women's health care disparities remain an understudied topic within the scientific community, despite the emergence of the Women's Health Movement in the 1960s. It wasn't until 1986 that women were allowed to participate in clinical research and trials. In 2017, the National Institutes of Health launched its first dedicated program to address disparities among women. Studies have consistently found disparities between biological men and women in areas such as pain management, treatment and diagnostics, and inclusion in clinical trials. These studies highlight significant differences in care and provide substantial evidence to support their findings.

Methods and Results: To address …


Comparison Of Morphological Characteristics And Dna Sequences Of Platyhelminthes Within Dabbling And Diving Ducks Species, Elise A. Betcher, Karolyn M. Kolstad, Ashley L. Marks, Marguerite C. Reitano, Alexander J. Train Apr 2025

Comparison Of Morphological Characteristics And Dna Sequences Of Platyhelminthes Within Dabbling And Diving Ducks Species, Elise A. Betcher, Karolyn M. Kolstad, Ashley L. Marks, Marguerite C. Reitano, Alexander J. Train

Research & Creative Achievement Day

Platyhelminthes, also known as flatworms, are among the most common parasites found in North American duck species. This phylum of parasites includes tapeworms and flukes. This study focused on identifying various Platyhelminthes found in Minnesota and Wisconsin wild ducks using both morphological characteristics and genetic sequencing. Both diving and dabbling species of ducks were used for this study, including green winged-teal (Anas carolinensis) and ring-necked ducks (Aythya collaris). Platyhelminthes were removed from legally harvested ducks and stained before examining and imaging under the microscope to identify key morphologic features for a presumptive identification. Subsequently, DNA was extracted …


Empowering Youth: Risk Factors Of Juvenile Delinquency, Shannon Keenan Apr 2025

Empowering Youth: Risk Factors Of Juvenile Delinquency, Shannon Keenan

Academic Festival

No abstract provided.


Mortality In Nasonia F2 Female Hybrid Wasps, Alettah Pegues Apr 2025

Mortality In Nasonia F2 Female Hybrid Wasps, Alettah Pegues

GS4 Student Scholars Symposium

No abstract provided.


Synthesis And Analysis Of 3,4- Diphenyl Pyridazines Derivatives As Breast Cancer Therapeutics, Joshua Osaghae Apr 2025

Synthesis And Analysis Of 3,4- Diphenyl Pyridazines Derivatives As Breast Cancer Therapeutics, Joshua Osaghae

GS4 Student Scholars Symposium

No abstract provided.


Modeling Sod1 Enzyme Mutations: Biochemistry Ii Lab Class Project, Jenna Bolduan, Elle K. Haumont Apr 2025

Modeling Sod1 Enzyme Mutations: Biochemistry Ii Lab Class Project, Jenna Bolduan, Elle K. Haumont

Research & Creative Achievement Day

Superoxide Dismutase 1 (SOD1) is an enzyme that catalyzes the detoxification of reactive oxygen species that cause damage to the body. Mutations of this protein can cause diseases, such as Amyotrophic Lateral Sclerosis (ALS). The structures of the SOD1 wild type and two of its deleterious mutations (A4V and L126*) were digitally modeled using the AI program AlphaFold3. Although a literature structure exists for A4V, no experimental structure data has been collected for L126*. The wild type and A4V structures were virtually identical, whereas the wild type and L126* structures had quite different features, with the mutant being smaller and …


Development Of A Qpcr For Detecting Borrelia Burgdorferi And Ixodes Tick Dna Simultaneously, Jenna Junker, Anthony J. Appicelli Apr 2025

Development Of A Qpcr For Detecting Borrelia Burgdorferi And Ixodes Tick Dna Simultaneously, Jenna Junker, Anthony J. Appicelli

Research & Creative Achievement Day

Black-legged ticks (Ixodes scapularis) and Lyme disease, caused by the bacterium Borrelia burgdorferi, are prevalent in the upper Midwest. Accurate determination of the percentage of Ixodes ticks that carry Lyme disease could help physicians and health experts develop treatment and prevention plans to curb the prevalence of disease. The purpose of this study was to see if accurate results for both Ixodes DNA and Borrelia DNA could be analyzed in the same qPCR assay for faster Lyme disease testing. Current testing in humans is achieved by running two separate diagnostic assays, an ELISA and Western Blot, both …


Female Acceptance Of Mates Is Consistent Across Different Sex Ratios And Male Proximities In Wood Frog (Rana Sylvatica) Breeding Aggregations, Alia Kabbaj, Laura Bousaid, Gabriella Lowney, Lindsey Swierk Apr 2025

Female Acceptance Of Mates Is Consistent Across Different Sex Ratios And Male Proximities In Wood Frog (Rana Sylvatica) Breeding Aggregations, Alia Kabbaj, Laura Bousaid, Gabriella Lowney, Lindsey Swierk

Binghamton University Undergraduate Journal

Sexual selection plays a crucial role in shaping reproductive strategies. We investigated the influence of sex ratio and male proximity on female acceptance of mates in wood frogs (Rana sylvatica). We hypothesized that females at a more even sex ratio would exhibit higher acceptance of males due to reduced male competition when compared to females at a more male-skewed sex ratio. Using digital video analysis of mating trials (n = 39), we quantified male proximity to females and female acceptance of males at two sex ratios – 1:4 (F:M) and 1:7. Males at a 1:4 sex ratio maintained …


Factors Influence Homeless People’S Psychological Well-Being And Suicidal Ideation, Pi-Ming Yeh Apr 2025

Factors Influence Homeless People’S Psychological Well-Being And Suicidal Ideation, Pi-Ming Yeh

Epsilon Sigma at-Large Research Conference

Introduction/Significance: About 582,462 individuals are experiencing homelessness in America. Homelessness is devastating, regardless of age. But for children, it can have serious physical, emotional, and psychological implications.

Purpose: The purpose of this study was to examine the influences of spiritual well-being, coping strategies, family interaction, and personality on psychological well-being, and suicidal ideation among people with homelessness.

Methods: Sixty people with homelessness were recruited in the Eastern Tennessee Downtown Day Center, USA. IRB was approved. This was a cross-sectional descriptive research design. Questionnaires were used to do data collection. SPSS 28.0 was used to do the data analysis. Descriptive …


A Comparison Of The Bacterial Communities Of The Yamuna River (India) And Mississippi River (Usa), Jacob Gareis, Osvaldo Martinez, Silas Bergen Apr 2025

A Comparison Of The Bacterial Communities Of The Yamuna River (India) And Mississippi River (Usa), Jacob Gareis, Osvaldo Martinez, Silas Bergen

Research & Creative Achievement Day

This study compared the bacteria in the Yamuna River in India and the Mississippi River in the USA. Water samples were taken from 11 sites (2 in the Mississippi River and 9 in the Yamuna River). The bacteria were identified using 16S rRNA gene sequencing. Some phyla such as Proteobacteria and Bacteroidetes were seen in abundance regardless of country. However, principal-component analysis showed three distinct groupings: Mississippi/Ganga/Tons and other Yamuna River locations (7 sites), Yamuna River at Delhi (2 sites), Yamuna River below Glacier (2 sites) Additionally, the Yamuna River below Glacier had the highest bacterial diversity, with a Shannon …


The Economic Impact Of The Emerald Ash Borer In Inver Grove Heights Mn, Nicholas Ruch, Noah Anderson Apr 2025

The Economic Impact Of The Emerald Ash Borer In Inver Grove Heights Mn, Nicholas Ruch, Noah Anderson

Research & Creative Achievement Day

Emerald Ash Borer (EAB) is an insect that bores under the ash tree's bark. This effectively kills the tree by girdling its cambium. In this analysis of EAB, we looked at the financial effect it had on Inver Grove Heights, Minnesota. Expert Tree Service removed most of their ash trees and provided us with data to help calculate how much it cost. Brian Swoboda, the head forester for Inver Grove Heights, provided us with all of the information about their plan to reforest.

In total, for the years 2022 and 2023, the removals done by Expert Tree Service cost $83,690.68 …


Plasma Profiling Reveals Proteins Specific To Primary Disease Origin Of Retroperitoneal Fibrosis, Thomas J. Pelowitz, Benjamin Hurr, Matthew Koster, Jaeyun Sung Apr 2025

Plasma Profiling Reveals Proteins Specific To Primary Disease Origin Of Retroperitoneal Fibrosis, Thomas J. Pelowitz, Benjamin Hurr, Matthew Koster, Jaeyun Sung

Research & Creative Achievement Day

Retroperitoneal fibrosis (RPF) is a rare inflammatory disease characterized by the formation of scar-like tissue in the retroperitoneum, which can lead to life-threatening obstructive nephropathy. RPF is typically a secondary disease, arising from various underlying conditions. Currently, no objective and highly accurate diagnostic methods exist. Identifying blood protein biomarkers specific to RPF could facilitate the development of objective minimally invasive diagnostic tests.

In this study, blood plasma samples were collected from 45 participants spanning 5 different primary causes of RPF, including idiopathic cases where no underlying condition was identified. Six participants without significant diseases at the time of sample collection …


The Shorthorn: May 11, 1954 Apr 2025

The Shorthorn: May 11, 1954

The Shorthorn Newspaper Collection: 1950s

No abstract provided.


The Shorthorn: April 20, 1954 Apr 2025

The Shorthorn: April 20, 1954

The Shorthorn Newspaper Collection: 1950s

No abstract provided.


The Shorthorn: March 2, 1954 Apr 2025

The Shorthorn: March 2, 1954

The Shorthorn Newspaper Collection: 1950s

No abstract provided.