Digital Commons Network^™

Establishing A Comprehensive Cancer Center: Integrating Holistic Care To Enhance The Well-Being Of Patients Undergoing Cancer Treatment, Morgan Rae Nelson

Architecture Theses

Cancer treatment is both physically and emotionally taxing, often intensified by care environments that prioritize clinical efficiency over holistic patient well-being. Thoughtful architectural design has the potential to transform these spaces into therapeutic environments that address the mental, emotional, and physical needs of patients. While holistic care models have gained traction, many facilities lack design elements that promote mental resilience, relaxation, and community connection.

Despite advancements in cancer care, a significant gap remains in how design addresses the mental and emotional well-being of patients. Many facilities continue to prioritize functionality over creating environments that foster holistic healing. This thesis investigates …

The Barefoot Lifestyle: Bringing Nature Back Into Health, Rachel Murray

Senior Honors Theses

The Barefoot lifestyle has many research questions revolving around the topic. Throughout the introduction, new solutions, such as natural way, will be spoken about broadly. The questions asked are to figure out why going barefoot has so many benefits physically, mentally, emotionally, and spiritually while introducing examples and other supportive studies and or cases. Additionally, the purpose of this research is to find a way back to a natural way of healing with specific examples of barefoot scenarios, trials of barefoot running and walking, and specific techniques to enhance the effects.

Exploring Variability Factors In Bur Oak Morphology, Karyn Morrissey

Celebrating Scholarship and Creativity Day (2018-)

This project, completed for Dr. Kate Cary in the Biology department, investigates how bur oak (Quercus macrocarpa) leaf morphology varies geographically. Using digitized herbarium specimens and provided data which included latitude, longitude, collection moth and year, leaf dissection, petiole length, temperature, and precipitation, the project visualizes patterns in morphology with a focus on leaf dissection (cm). Maps were generated both at the state level (Minnesota) and national level, depicting bur oak locations and morphology trends across different seasons (January-May and June-December) over the past century.  The importance of this data lies in its ability to reveal how environmental factors like …

The Effect Of Calorie Restriction On Humoral Responses Towards The Influenza Vaccine, Grayson Kobluk

Celebrating Scholarship and Creativity Day (2018-)

Calorie restriction (CR) - a reduction in caloric intake without malnutrition - has been widely studied for its impact on lifespan and the onset of age-related diseases. Emerging research indicates that CR also influences immune function, though its effects can vary depending on the degree of restriction, duration, and individual characteristics. This study examined how CR effects vaccine-specific antibody responses following influenza vaccination. Male and female mice were maintained on either a control diet or a calorie-restricted diet and vaccinated with an inactivated influenza virus vaccine. Antibody titers were measured 28 days post-vaccination to evaluate the magnitude of the humoral …

Effect Of Glycation On The Binding Interactions Of Serum Albumin And Silver Nanoparticles, Megan Kirk

Celebrating Scholarship and Creativity Day (2018-)

Nanoparticles are particles ranging from 1-100 nanometers in size. Most nanoparticles, upon contact with biological matrices, are immediately coated with proteins, forming the protein corona, which can alter the structure and function of proteins. Despite the tremendous advancement of nanotechnology over the last decade, the interactions of nanoparticles with proteins are not well characterized. This project investigates the effect of glycation on the binding interactions of HSA, the most abundant protein in human blood, with silver nanoparticles using various spectroscopic techniques. This is important because in diabetic patients, HSA is exposed to high concentrations of glucose over extended periods of …

Life In Plastic? Not So Fantastic: Marine Plastic Pollution On San Salvador Island, Dayna Wiley

Celebrating Scholarship and Creativity Day (2018-)

Marine plastic pollution, also known as marine macroplastic debris (MMD), impacts many aspects of marine ecosystems. MMD is defined as macroplastic (> 5mm) objects that are deposited in the ocean and are found floating in the water column or washed up on beaches. MMD washup is significantly affected by ocean and wind currents. The Antilles Oceanic Current and the Trade Winds move west across the Atlantic Ocean, and thus were predicted to cause more MMD deposition on the eastern side of San Salvador Island, Bahamas. Beaches on the North (Graham’s Harbor), South (French Bay), East (East Beach), and West (Columbus …

Exercise Physiological Insights Into Exercise-Induced Muscle Cramping: Blood Lactate And Creatine Kinase As Biomarkers In College Students, William Yu

Celebrating Scholarship and Creativity Day (2018-)

Creatine kinase (CK) is an enzyme that's found in the skeletal muscle, heart muscle and brain. When any of these tissues are damaged, they leak creatine kinase into your bloodstream. Elevated CK levels may indicate muscle injuries, cramping, or disease1. There are different types of CK, which are also known as isozymes for the cytoplasm, CK-MM, CK-MB, and CK-BB. CK-MM focuses on musculoskeletal, CK-MB focuses on heart muscles, and CK-BB focuses on the brain tissue. There are also two isozymes in the mitochondria15. Cramping is common problem amongst runners and can be described as “painful, spasmodic contraction of the skeletal …

The Effects Of Climate Change On The Spread Of Mosquito-Borne Diseases, Lauren Provoncha, Sarah Franta, Portia Lawrence

Celebrating Scholarship and Creativity Day (2018-)

This paper examines the impact of climate change on the spread of mosquito-borne diseases, focusing on how rising temperatures, altered precipitation patterns, and extreme weather events influence mosquito habitats and disease transmission. It explores the ecological and public health implications of these shifts and highlights the importance of understanding climate-disease dynamics to inform effective prevention and intervention strategies.

Ecological Consequences Of Variable Glacial Melting On Arctic Biodiversity: Trophic Shifts And Community Dynamics, Aislyn Malone, Audrey Swart

Celebrating Scholarship and Creativity Day (2018-)

Our project investigated the profound impacts of increasing glacial melting on various trophic levels, habitats, and other ecological processes.

Psychology Across The Spectrum: Self-Regulation And Emotional Control In Autism Spectrum Disorder, Emily Oswald

Celebrating Scholarship and Creativity Day (2018-)

This paper explores the complex relationship between self-regulation, emotional control, and autism spectrum disorder (ASD), emphasizing the cognitive, behavioral, and emotional challenges autistic individuals often face. Drawing on contemporary research, it highlights how self-regulation is linked to cognitive and language development, while difficulties in emotional control can result in increased behavioral problems and mental health issues. The paper examines the dual role of behaviors like stimming—both as coping mechanisms and as forms of authentic self-expression—and addresses the tension between traditional behavioral interventions such as Applied Behavior Analysis (ABA) and emerging neurodiversity-affirming practices. This paper also discusses the neurodiversity movement, noting …

Korean Adoptees: Peer And Parental Socialization, Internalized Racism, And Diasporic Identity, Josie Braun, Majel Baker, Jae Kim, Richard Lee

Celebrating Scholarship and Creativity Day (2018-)

There have been approximately 110,000 Korean children adopted to the United States since the end of the Korean War in the 1950s (as cited in O. M. Kim et al., 2024). Many of these transracial adoptees were, and still are, placed into white, middle-class, Judeo-Christian families (Reynolds et al., 2017), resulting in what is termed transnational, transracial adoption (Lee, 2003). Historically, these white adoptive parents were advised to raise their Asian adoptee(s) no differently than a white biological child, with the goal of assimilation (as cited in Lee & Miller, 2009). As a result, Korean Adoptees may internalize harmful, White …

Highly Pathogenic Avian Influenza Outbreak Preparedness In The United States: A Scoping Review, Emma J. Gurley

Honors Theses

In order to gauge preparedness for an outbreak of highly pathogenic avian influenza (H5N1) in the United States, a scoping review of the current literature was conducted. This process involved (1) identifying the research question, (2) identifying studies relevant to the topic, (3) selecting studies for inclusion (4) charting the data, and (5) analyzing and reporting the final data. Ultimately, seventeen studies were deemed appropriate for examination within this scoping review and several key themes were identified. The results emphasize the importance of adopting a One Health approach, the key role that vaccination may well play in preventing the spread …

Neutrosophic Wald Distribution With Applications To Reliability Analysis, Afrah Al Bossly, Adnan Amin

Neutrosophic Sets and Systems

No abstract provided.

Tree Soft Set And Decision-Making Approaches For Tourist Satisfaction Assessment Of Tourist Attractions, Yuxia Yan

Neutrosophic Sets and Systems

No abstract provided.

Estimating The Prevalence Of Delay In Comprehensive And Expressive Language Development In Preschool Children In Pichincha, Ecuador Based On Plithogenic Statistics, Andino-Acosta María Soledad, Guerrero-Olalla Mercy Paulina, Lima-Rosero Patricia Elizabeth, Moreno-Pramatárova Mila, Ruales-Paredes Salomé Shayana, Tapia-Tapia Sylvia Ibeth, Unda-Vargas Ivonne Cristina

Neutrosophic Sets and Systems

No abstract provided.

Evaluating Risk And Return Of Corn And Soybean Marketing Strategies Using Monte Carlo Simulation Methods, Johanna Ilves

Department of Agricultural Economics: Dissertations, Theses, and Student Research

This study evaluates the performance of pre-harvest marketing strategies for corn and soybeans, using Monte Carlo simulation techniques. Given the increasing volatility in commodity prices and the evolving landscape of agricultural markets, producers face growing challenges in developing effective marketing plans that manage risk and enhance profitability. This thesis examines thirteen marketing strategies from 2008 to 2024, including benchmark harvest-only sales and various pre-harvest futures contract approaches. Historical futures price data for December corn and November soybean contracts were used to simulate 1,000 marketing outcomes per strategy per year, capturing a broad range of market conditions. Key performance indicators such …

Treading Lightly: The Ethics Of Instructor Il/Legibility And Neutrality In The Classroom, Marcus A. Woodman

Department of English: Dissertations, Theses, and Student Research

Instructors in the classroom often describe their experiences teaching as being a performance, which often combines authenticity with boundaries to keep certain aspects of the instructor’s life out of the classroom. For queer instructors, their performance may be especially complicated; since queer identity is less visible than other types of identities, instructors must also weigh whether or not to come out to their students. In our current political moment, where queerness has yet again become a scrutinized topic (especially when in proximity to youth), teachers have an even more difficult decision to make.

This thesis uses queer theory and queer …

Walleye And Sauger Movement And Entrainment In Lewis And Clark Lake, William Joseph Radigan

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Walleye Sander vitreus and Sauger Sander canadensis are both socioeconomically important sportfish species in Lewis and Clark Lake, an interjurisdictionally managed mainstem Missouri River reservoir fishery. Since 2011, adult catch per unit effort (CPUE) of both Walleye and Sauger has remained at approximately 50% of pre-2011 levels. A presumed reason for the suppressed CPUE of adult Walleye and Sauger is substantial entrainment of larval and adult fish resulting from the reservoir’s high turnover rate (7.2 d). Acoustic telemetry was used to quantify adult movement and entrainment and ichthyoplankton trawls were used to assess larval entrainment. Relative importance of factors driving …

“As If The Devil Was In Her”: Fanny Fern’S Remaking Of Authorship In The Nineteenth Century, Rowan S. Q. Havranek

Honors Program: Senior Projects (Public)

Fanny Fern revolutionized nineteenth-century literature with her unapologetically blunt and insightful commentary on social norms, education, women’s rights, and more. As a columnist for The New York Ledger, Fern challenged the conventional boundaries placed on women, blending her personal observations and experiences with sharp social critique. Because of her unflinching style and writings that addressed a wide range of topics, she became one of the most well-paid and widely read authors of her time. Yet, she was also subjected to harsh judgment. The media, particularly in the hands of her second husband, was used to damage her reputation, yet Fern …

Illustrating Insects: Using Art To Encourage Experiences In Entomology, Nia Kaufmann

Honors Program: Senior Projects (Public)

The goal of this creative project is to use art to highlight the diversity of our insect neighbors and encourage others to explore their local environments. In order to accomplish this, I created a poster-sized illustration of five insects I’ve encountered on the University of Nebraska-Lincoln’s City Campus. All insects are posted within the silhouette of Memorial Stadium, each with an ecological and personal significance. The contrast of a well-known building with less popular insects invokes the audience to reconsider how much attention they pay to the wilderness around them.

Keywords: Entomology, Natural Biodiversity, Illustration, Insects, Appreciation of Nature

Landscape Effects On The Beneficial Arthropod Community In Agriculturally Dominated Environments, Hannah E. Stowe

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Ecosystem services in agriculturally dominated regions rely, at least in part, on arthropods. Environment and biodiversity influence beneficial arthropods in population size, community structure, diversity, and ecosystem service provisioning. Predation is among the most important services provided by arthropods in agroecosystems. Understanding what alters predation and predator activity can support the successful application of biological control and, more broadly, integrated pest management. Land use and edge adjacency, field characteristics, landscape, seasonality, and diel period all alter predatory behavior. Crop fields dominate Nebraska agroecosystems, although interspersed perennial grasslands persist through the Conservation Reserve Program (CRP). Such grasslands supply crucial resources and …

A Case Study On Readiness Of Engineers In Agricultural Technology Start-Ups, Katie Marie Mowat

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation explores the perceptions of practicing engineers regarding the skills necessary to be workforce-ready at agricultural technology (ag-tech) start-ups in the Midwestern United States. A qualitative case study methodology is leveraged, combining both interview and job description data. Given their uniqueness, the study divides the ag-tech start-up industry into two subcases: livestock and cropping systems. The Work Readiness Integrated Competence Model (WRICM) is used as the theoretical framework for this study and informs the conceptual framework and analysis processes. The study identified skills that fit into thirteen distinct categories, which are further grouped into four overarching resource groups. Skills …

Gene Editing Approaches To Improving Grain Amino Acid Profiles In Maize And Sorghum, Joseph Preston Hurst

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Maize grain is deficient in lysine. While the opaque2 mutation increases grain lysine, o2 is a transcription factor that regulates a wide network of genes beyond zeins, which leads to pleiotropic and often negative effects. Additionally, the drastic reduction in 19kDa and 22kDa alpha-zeins causes a floury kernel, unsuitable for agricultural use. Sorghum, closely related to maize, has a similar lack of lysine that can be corrected with prolamin alteration and also subject to the same deleterious kernel texture. CRISPR/cas9 gives researchers the ability to directly target genes of interest. In this research, gene editing was used to specifically target …

Understanding The Context Of Bullying: Examination Of The Healthy Context Paradox And Peer Acceptance For Students With Disabilities, Catherine Mae Carney

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The purpose of this dissertation study was to examine how perceptions of school climate and social acceptance influence the relationship between bullying victimization and anxious and depressive symptoms for youth with and without disabilities. Students with disabilities are at increased risk for involvement in the bullying dynamic, both by bullying others and by experiencing victimization. Victims of bullying are more likely to experience peer rejection and greater internalizing problems, including higher levels of anxious and depressive symptoms. Research suggests that school-wide efforts to reduce bullying may leave some youth vulnerable to worse psychosocial outcomes, which has been called, “the healthy …

Belly Dance In Nebraska: Identity, Social Acceptance, And Perseverance, Alex R. Mohr

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Belly dance is an art form as well as an often-contested practice due to tensions over dress, terminology and cultural practices within the belly dance community because the dance originated outside the United States. Additionally, there is often a need to prove the legitimacy of the dance to those outside its sphere because it is often stigmatized due to the early association with exotic dancing. Belly dance is inherently geographic, as seen through its places of origin, music and movement styles, global spread, practitioners, and spaces of practice. However, it has not been well-represented in geography, and there is also …

Optimizing Nitrogen Management: Assessing Nitrate Transport In The Deep Vadose Zone And Its Impact On Groundwater Quality In East-Central Nebraska, Muili O. Lawal

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Groundwater contamination by nitrate (NO₃-N) is a growing environmental and public health concern driven largely by intensive agricultural fertilizer applications. The vadose zone plays an important role in NO₃-N transport, influencing groundwater quality and agricultural sustainability. This study investigated NO₃-N leaching dynamics in the deep vadose zone of Water Quality Sub-Area 30 (WQA30) within the Lower Loup Natural Resources District (LLNRD), northeast of Columbus, Nebraska (mean groundwater NO₃-N: 20.3 mg/L), using soil cores from 16 shallow (to 6.1 m) and four deep (down to 25.9 m) across four zones, two with inorganic fertilizer (Zones 1 and 4) and two with …

Constructing An Attractive Targeted Sugar Bait For Reducing Mosquito Populations, Xi Xian Ng

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Mosquito-borne pathogen transmission continues to pose a significant burden to global public health, well-being, and economic productivity. In the absence of universally available vaccines and amidst rising insecticide resistance that leads to product failures, there is an urgent need to develop new tools to mitigate mosquito-borne disease risk. Two general strategies exist to reduce transmission risk: personal protective measures and area-wide chemical interventions. Attractive Targeted Sugar Bait (ATSB) systems leverage the sugar-feeding behavior of mosquitoes—critical for sustaining their flight, metabolism, development, and fecundity—by delivering oral toxicants through attractively formulated sugar baits. This study aimed to develop an optimized ATSB formulation …

“Re-Storying” Anne Shirley And The Adhd Child: A Crip Genealogy Of Anne Of Green Gables, Darian Aleyna Wilson

Department of English: Dissertations, Theses, and Student Research

This thesis explores the contested nature of Attention Deficit Hyperactivity Disorder (ADHD), focusing on its cultural and historical constructions. While ADHD has been included in the Diagnostic and Statistical Manual of Mental Disorders since 1980, its legitimacy remains a subject of debate across medical, disability studies, and historical scholarship. Using Eli Clare’s critique of diagnosis as a tool rather than a fact, this project examines how ADHD is both pathologized and re-storied within societal and medical discourses. It highlights the tension between medical classifications and lived experiences of those diagnosed with ADHD, particularly in the context of girlhood.

The central …

Association Of Nucleoside Reverse Transcriptase Inhibitor Use With Reduced Risk Of Alzheimer's Disease Risk, Joseph Magagnoli Ph.D., Ms, Meenakshi Ambati, Tammy H. Cummings, Joseph Nguyen, Claire C. Thomas, Vidya L. Ambati, S. Scott Sutton, Bradley D. Gelfand, Jayakrishna Ambati

Faculty Publications

INTRODUCTION

Inflammasome activation is implicated in Alzheimer's disease (AD). We previously demonstrated that nucleoside reverse transcriptase inhibitors (NRTIs), drugs approved to treat human immunodeficiency virus (HIV) and hepatitis B, also inhibit inflammasome activation.

METHODS

We evaluated the association between NRTI exposure and subsequent development of AD in the United States Veterans Health Administration over a 24-year period and in the MarketScan database over a 14-year period using propensity score-matched multivariate Cox hazards regression and Kaplan–Meier analyses.

RESULTS

We report that in humans, NRTI exposure was associated with a significantly lower incidence of AD in two of the largest health insurance …

Unsupervised Machine Learning Techniques To Categorize Genomic Islands, Lijie Zhou

All Theses

Unsupervised Machine Learning (ML) techniques are powerful tools for identifying similarity patterns and can be utilized to categorize the data into related groups. This study showcased the applications of unsupervised methods, namely hierarchical clustering to carefully determine related groups of newly identified genomic islands (GIs). Genomic islands are mobile genetic elements integrated into bacterial chromosomes. Gis can impact the evolution of bacteria for example by carrying virulence or metabolic genes. Precisely identifying Gis calls for a sophisticated process which we recently implemented as an already-published tool called TIGER which stands for Target/Integrative Genetic Element Retriever (TIGER). TIGER identifies mobile DNAs …