Digital Commons Network^™

Population: The Who Of Biodiversity Law, Andrew W. Torrance, Bill Tomlinson

Texas A&M Journal of Property Law

This Article investigates the impacts of human population, including distribution and growth, on biodiversity at every level—the biosphere, ecosystems, communities, populations, and individual organisms. It assesses how legal frameworks around the world address the pressures of human population on biodiversity. This Article explores how factors such as population size and migration contribute to biodiversity loss, with a focus on diverse regions around the globe. This Article offers a comparative overview of population-related laws in regions including North and South America, Europe, Oceania, Asia, and Africa. Key legislation, like the U.S. National Environmental Policy Act, the UK’s Environment Act 2021, …

Assessing The Status And Distribution Of The Many-Lined Salamander (Stereochilus Marginatus) In Florida, Aubrey Heupel Greene, Kevin W. Christman, Jonathan D. Mays, Daniel U. Greene, David A. Steen

Florida Field Naturalist

To better understand the contemporary status and distribution of the many-lined salamander (Stereochilus marginatus) at the southern extent of the species’ range, we surveyed for the species within Florida between 2022 and early 2024, including both known historical locations and additional sites with apparently suitable habitat within occupied drainages. Prior to our study, many-lined salamanders had not been documented in the state since 1991 but we recorded 23 observations (eight adults and 15 juveniles) from two sites; the relatively few detections precluded analyses to better understand activity patterns or evaluate habitat quality. Many-lined salamanders remain extant in Florida but face …

Arthropods Collected From Common Yellowthroats (Geothlypis Trichas) On Vaca Key, Florida, Lawrence J. Hribar

Florida Field Naturalist

No abstract provided.

Veracity Enhancement Using Non-Invasive Brain Stimulation: A Systematic Review, Alice Hou, Shahrukh Naseer, Abram Brummett

Posters

For decades, non-invasive brain stimulation (NIBS) techniques like Transcranial Magnetic Stimulation (TMS) and Transcranial directcurrent stimulation (tDCS) have been used in clinical settings as forms of neuromodulatory treatment for depression and other neurodivergent disorders. In recent years, there has been increased research in utilizing the non-invasive techniques to enhance cognition beyond one’s baseline, including language, memory, moral, and veracity enhancements. Due to the lack of systematic reviews in the growing field of veracity enhancement, we aim to provide a concise, summative overview of current research studying the impacts of NIBS on truthfulness, as well as its ethical dilemmas and future …

Investigation Into The Microbiome Of Blow Fly Eggs Using Microseqtm Id, Samantha S. Davis, Drusilla Sheridan, Jennifer Rosati

Undergraduate Research

There is little published research characterizing the microbiome associated with blow fly eggs and how they may affect the colonization behaviors of certain blow fly species. Once deposited, blow fly eggs are rapidly introduced to a diverse range of microorganisms, which can vary depending on the species of blow fly, the environment, and the decomposition stage of the substrate (Junqueira et al., 2017). Since blow flies are among the first insects to colonize decomposing remains, the microbial communities present on their eggs could serve as key indicators of the decomposition stage at the time of egg-laying, thus providing a potential …

Decoding Oncology-Focused Biotechnology Firms: Lifecycle Analysis And Predictive Insights For Valuation From A Junior Associate's Perspective, Kesav P. Chandrasekhar

Finance Undergraduate Honors Theses

Oncology-focused biotechnology firms present unique valuation challenges due to high R&D costs, long development timelines, and uncertain clinical outcomes. This thesis addresses such challenges by integrating the clinical development lifecycle with financial valuation models to provide predictive insights into company value. A structured framework is developed that primarily focuses on stage-specific probabilities of success (PoS) for drug candidates and their impact on firm valuation, embedded in techniques such sum-of-the-parts (SOTP) analysis. By quantitatively linking clinical trial phases and likelihoods of approval to cash flow projections, the model enables a more realistic, risk-adjusted estimation of a biotech firm's worth. Through lifecycle …

Dental Microwear Of Miocene Primates From The Carpathian Basin, Rudabánya, Hungary, Anna K. Wilcox

Biological Sciences Undergraduate Honors Theses

This study reconstructs and compares the dietary habits of the late Miocene primates Anapithecus hernyaki and Rudapithecus hungaricus by analyzing dental microwear patterns on fossilized teeth recovered from Rudabánya, Hungary. Previous research suggested that these sympatric species were both primarily frugivores but were unable to separate them by diet. However, earlier studies were limited by smaller sample sizes and less advanced methodologies. This study used an expanded sample and modern microwear texture analysis techniques to compare molar and incisor microwear patterns between the two species. Results revealed that Rudapithecus molars exhibited higher complexity compared to Anapithecus molar complexity, suggesting a …

Phosphatase Activity And Structure Of The Spoiie Protein In Clostridioides Difficile, Kathryn Wootten

Biological Sciences Undergraduate Honors Theses

Clostridioides difficile is a major cause of severe gastrointestinal infections and diseases, particularly in healthcare settings. Because of its ability to produce infectious endospores by sporulation, the protein SpoIIE, which is known to play a role in the regulation of this process, is being explored as a potential therapeutic target. In order to gain better insight into the structure and function of this protein, a concentrated and purified sample of the protein must be obtained. The goal of this study was to determine the conditions that would yield the highest amount of SpoIIE. The density of the cultures of bacteria …

Identifying Novel Molecular Targets To Induce Ferroptosis In Drug-Tolerant Cancer Cells Through Computational Modeling, Haris J. Rana

Biological Sciences Undergraduate Honors Theses

Ferroptosis is an iron-dependent, reactive oxygen species (ROS)-driven form of regulated cell death in which the cell membrane is degraded by lipid peroxidation. It is regulated by multiple enzymes, such as glutathione peroxidase 4 (GPX4), which prevents membrane degradation by reducing lipid peroxides and protecting cells from oxidative damage. When inhibitors like RSL3 target GPX4, lipid peroxides build up, and toxic ROS compromises membrane integrity. Traditional anticancer treatments, such as most chemotherapies, aim to eliminate tumor cells by damaging DNA and triggering apoptosis. However, resistance to apoptosis is a “hallmark of cancer,” often resulting in treatment failure. As a distinct …

Structural Stability Of Fgf1-Fgf2 Dimer Established Via Salt Bridges With Mutation K296q, Ashleigh Letterman

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast Growth Factors (FGFs) are a family of cell-signaling proteins. FGF, specifically the FGF-1 subfamily, which contains FGF-1 and FGF-2, is important in several biological functions such as wound healing, cell proliferation, and angiogenesis. FGF-1 has cell proliferation properties and FGF-2 has angiogenic properties. These FGFs have great potential for wound-healing therapy medications...

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Temperament And Screen Time Into Adulthood, Kareem Barbis

Electronic Theses and Dissertations

The possible correlation between language skills, temperament, and screen time in adulthood is understudied. It was hypothesized that high effortful control scores and low childhood screentime would corelate with higher cognitive reflection scores and higher language skills. Using a correlational design, 162 participants were studied (M age = 19.17 years old, 80% female, 86% White, 6% Hispanic). Participants completed an adapted version of the Adult Temperament Questionnaire (Evans & Rothbart, 2007), Cognitive Reflection Test (CRT; Fredrick, 2005), the Cognitive Reflection Test 2 (CRT-2; Thompson & Oppenheimer, 2016), Thompson & Oppenheimer, 2016), a childhood screen time questionnaire, a bilingualism questionnaire, and …

Studies To Delineate The Structure And Function Of The Human Ventricular Myocardium In Subjects With Type-Ii Diabetic Cardiomyopathy, Haritha Keerthi

Open Access Theses & Dissertations

Heart failure, an abnormal heartbeat, and sudden death are all possible outcomes of preexisting or underlying cardiac disease. Heart disease is highly correlated with diabetes, causing heart pain and shortness of breath. In patients without other cardiac conditions, diabetic cardiomyopathy is a process that affects the myocardium over a long period of time. This disease has a complicated pathophysiology that can be broken down into processes that lead to diastolic and/or systolic dysfunction. However, the pathophysiological differences between normal, diabetic, and diseased cardiac tissues have not been thoroughly studied. Therefore, in this research, we directed our efforts to perform a …

Overcoming Barriers: Reducing Prostate Cancer Disparities For Black Men, Hallie Klein-Immroth, Ola Brown, Shamara Colley, Rebecca Paredes, Susan Lee

Research Methods Poster Session 2025

No abstract provided.

Life History Inhibits Deleterious Effects Of Dams On Genetic Health And Structure Of A Headwater Stream Fish, Riley Phelps

Electronic Theses and Dissertations

Habitat loss, fragmentation, and land use changes in river networks are common globally. The resulting fragmentation of landscapes and riverscapes threatens biodiversity and can affect dispersal and subsequently, gene flow and genetic health of species. Headwater streams are an integral part of river networks and contribute to biodiversity by providing habitat for temporary and permanent residents, yet they are easily altered and fragmented. The sandhills chub (Semotilus lumbee) is an endemic headwater leuciscid that lives in highly fragmented streams of the sandhills ecoregion in North and South Carolina, USA. New knowledge on the population genetics of the sandhills chub is …

Modeling Dna Repair In Escherichia Coli Using A Boolean And Stochastic Framework, Gabrianne Ivey

All Theses

DNA can be damaged through both internal and external sources. Therefore, cells have created methods to repair DNA damage. In Escherichia coli, the system responsible for DNA repair is termed the SOS response. This system consists of more than 50 genes and contains three main repair pathways: nucleotide excision repair, translesion synthesis, and homologous recombination. The response is initiated when DNA lesions result in the accumulation of single-stranded DNA (ssDNA). The protein RecA is activated by binding to ssDNA and is then denoted RecA*. RecA* assists in the auto-cleavage of LexA which is the primary repressor protein involved in …

Soil-Based Emissions And Context-Specific Climate Change Planning To Support The United Nations (Un) Sustainable Development Goal (Sdg) On Climate Action: A Case Study Of Georgia (Usa), Davis G. Nelson

All Theses

Soil-based emissions from land conversions are often overlooked in climate planning. The objectives of this study were to use quantitative data on soil-based greenhouse gas (GHG) emissions for the state of Georgia (GA) (USA) to examine context-specific (temporal, biophysical, economic, and social) climate planning and legal options to deal with these emissions. Currently, 30% of the land in GA has experienced anthropogenic land degradation (LD) primarily due to agriculture (64%). All seven soil orders were subject to various degrees of anthropogenic LD. Increases in overall LD between 2001 and 2021 indicate a lack of land degradation neutrality (LDN) in GA. …

Don’T Be A Big Baby: Phenotypic Novelty In The Facultative Paedomorph Ambystoma Talpoideum., Andrew S. Kanes

All Theses

This thesis explores the relationship between heterokairy and the skin microbiota of amphibians, specifically focusing on the facultatively paedomorphic salamander, Ambystoma talpoideum. Heterokairy refers to variations in developmental timing that generate phenotypic novelty within life stages. The first chapter investigates how reordering metamorphosis relative to sexual maturation affects the skin microbiota in this species. By sampling different life stages—larval, paedomorphic, and metamorphic—results show the emergence of novel microbial combinations, resulting from both microbial gain and loss in the heterokairic paedomorphic stage. These findings suggest that changes in microbial communities may lead to phenotypic novelty and have broader eco-evolutionary implications. …

Tradespace Exploration With Statistical Modeling Techniques And Immersive Visual Representation In Virtual Environments, Nikhil Raj

All Theses

Statistical modeling techniques combined with virtual reality (VR) visualization offer powerful new approaches to tradespace exploration in engineering design. The research presented addresses the challenge of analyzing and communicating insights from complex multidimensional datasets, particularly for autonomous ground vehicle systems.

Beginning with a review of statistical methods—including Principal Component Analysis (PCA), Analysis of Variance (ANOVA), and correlation analysis—the study examines their applications in tradespace exploration. Building on this foundation, three distinct visualization pathways connecting MATLAB data to virtual environments are developed and evaluated: VRML representation, STL conversion, and Blender integration. Each approach is assessed for its ability to maintain data …

Investigating Stress Hormone Variations In Green Frogs (Lithobates Clamitans) During The Mating Season, Abby Mciver

Electronic Theses and Dissertations

Monitoring stress hormones in wildlife populations is increasingly used to understand how human activities may impact the environment. The goal of this study was to quantify corticosterone in green frogs (Lithobates clamitans) at baseline levels and in response to an acute stressor throughout the mating season. The project was conducted from May to September of 2024 at Bays Mountain Park in Kingsport, Tennessee. Corticosterone levels were determined over six consecutive days each month from May to September using a non-invasive dermal swab technique. Additionally, body metrics, water chemistry, and weather and habitat conditions were evaluated on each sampling …

Evaluating The Effects Of Co₂ And Uv-B On Sporobolus Virginicus (L.) Kunth Growth Under Open Top Chamber: A Comparison Of Silicon Nanoparticle-Treated And Untreated Plants, Suhaila Humaid Ablooshi

Theses

The study focused at how silicon nanoparticles (SiNPs; 50 mg/L) affected the growth, photosynthetic efficiency, and biochemical responses of the salt-tolerant halophyte Sporobolus virginicus in four different environments. They are control, high CO₂, UV-B radiation, and a mix of high CO₂ and UV-B. Plants that were treated with SiNPs showed big changes in their shape, such as more biomass, bigger leaf area, and better root systems in all conditions. The use of combined stress treatments caused a big increase in the levels of chlorophyll a, chlorophyll b, total chlorophyll, and carotenoids. As a result, that the plants were better at …

Encapsulation Of Lactobacillus Reuteri Dsm 17938 In W/O/W Emulsion: Influence Of Oil Type On Viability And Oxidative Stability, Nora Mohamed Alantali

Theses

Probiotics, known for their wide range of health benefits, have been gaining recognition on their effects on the gut-brain axis. This axis, operated via various pathways, can be modulated by the type and functions of probiotics found in the gut microflora. However, probiotics face several stress factors before reaching the gut which hinders them from being functional. The main objective of this thesis was to construct a stable double-emulsion-based delivery system for probiotics, which can act as a barrier against the harsh conditions of the digestive system. Lactobacillus reuteri DSM 17938 was loaded in a water-in-oil-in-water Pickering double emulsion system, …

Structural And Functional Characterization Of The Sos Pathway Genes (Sos1, Sos2, And Sos3) In Avicennia Marina: Insights Into Salinity Stress Tolerance, Mariam Obaid Alzaabi

Dissertations

Abiotic stress is a major challenge for agricultural productivity. Salinity stress is a vital environmental constraint that significantly limits plant growth and reduces crop yield worldwide. Halophytes, such as Avicennia marina, offer unique opportunities to dissect adaptive mechanisms underlying salt tolerance. This study focuses on the structural and functional characterization of the Salt Overly Sensitive (SOS) pathway genes (SOS1, SOS2, and SOS3) from A. marina. Full-length cDNAs of AmSOS1, AmSOS2, and AmSOS3 were cloned and characterized. The sequence analysis of these genes compared to the respective orthologs revealed high similarities and conservation of all …

Origins: Nutritional Profile Of Children Aged One Year In A Longitudinal Birth Cohort, Sarah Whalan, Poonam K. Pannu, Rachelle A. Pretorius, Alexander J.J. Scherini, Sonia Gregory, Susan L. Prescott, Desiree Silva

Research outputs 2022 to 2026

Background: Dietary intake during the first year of life is a key determinant of a child’s growth and development. ORIGINS is a longitudinal birth cohort study investigating factors that contribute to a ‘healthy start to life’ and the prevention of non-communicable diseases. Methods: This descriptive cross-sectional study aims to describe the dietary intakes of one-year-old children participating in ORIGINS and compare these to the Australian Dietary Guidelines and Nutrient Reference Values (NRVs). Between 2020 and 2023, dietary intake data were collected on 779 one-year-old children using a Food Frequency Questionnaire (FFQ). The analysis explored milk intake (breastmilk, infant formula, and …

Revised Phylogeography Of The Common Brushtail Possum (Trichosurus Vulpecula) Reveals New Insights Into Genetic Structure Across Australia, Shelby C. Middleton, Robert A. Davis, Kenny J. Travouillon, Anna J.M. Hopkins, Harriet R. Mills, Linette S. Umbrello

Research outputs 2022 to 2026

Understanding genetic relationships within species is essential for identifying distinct genetic lineages and informing conservation strategies, particularly for species with fragmented or widespread geographic distributions. One such widespread species that has suffered declines across Australia, despite remaining common in some areas, is the common brushtail possum (Trichosurus vulpecula), a nocturnal and arboreal marsupial. Previous genetic studies on brushtail possums had limited sampling, which has precluded a comprehensive assessment of the relationships within the species and genus. Using both single nucleotide polymorphism markers and the mitochondrial cytochrome b gene, this study employed phylogenetics, ancestry coefficients, and tested genetic differentiation, to examine …

Effect Of Relative Age On Gross Motor Coordination Development, Considering Biological Maturity And Sex, Xiaoyu Zhang, Gaël Ennequin, Anthony J. Blazevich, Sébastien Ratel

Research outputs 2022 to 2026

Objective: This study aimed to investigate the effect of relative age on gross motor coordination (GMC) development, taking into account biological maturity and sex. Methods: 729 participants aged 10 to 16 years completed three GMC tests newly designed to minimize the potentially confounding effects of physical fitness. The tests included a Hand-Foot coordination test, Dribbling-Targeting test (DT test), and a T balance and agility test (T test). Relative age was determined using birth quartiles: BQ1 (January–March); BQ2 (April–June); BQ3 (July–September); and BQ4 (October–December). Regarding biological maturity, the participants were categorized according to their estimated peak height velocity (pre- and post-PHV). …

Risk Factors For Mismatches In The Art Laboratory: An Analysis Of 73,719 Electronic Witnessing Points, Maria Forbrig, Kelli Peirce, Chris Copeland, Jay Natalwala, Vincent Chapple, Yanhe Liu

Research outputs 2022 to 2026

Research question: What are the risk factors for mismatches (involving or not involving biological material) and critical mismatches (CMM; involving biological material) in an assisted reproductive technology laboratory equipped with an electronic witnessing system (EWS)? Design: In total, 73,719 witnessing points were extracted retrospectively from an EWS database, representing 11,210 consecutive treatment cycles performed at Fertility North between January 2016 and July 2023. Results: Overall, 138 (0.19%) mismatches and 16 (0.02%) CMM were identified during the study period. Significant differences were detected in both mismatch (P = 0.003) and CMM (P = 0.038) rates between different time periods of the …

Useful Measures Of Adult Attachment And Object Relations In Psychotherapy, Matilde A. Torallas Huerta

Dissertations

This is a literature review of objective and projective measures of attachment and object relations in adults, with the objective of reviewing outstanding research to identify the key factors for adult attachment assessment considered within attachment and object relations theories, what measures of adult attachment styles and dysfunction work best, and to provide key themes of assistance in the measurement of attachment and object relations in adult clients in psychotherapy. Theoretical foundations of attachment and object relations theory are reviewed as well as objective and projective instruments grouped by format. The 10 themes found to be useful in the assessment …

Shades Of Families: Exploring Intersectionalities Of Cross-Cultural Parenting Experiences In The U.S., Shu-Han Huang

Dissertations

As multiracial and multicultural families continue to grow across the United States, parents must navigate evolving cultural identities, systemic inequities, and increasing social and emotional pressures. These realities underscore the need for parenting resources that are both culturally responsive and emotionally supportive. This transcendental phenomenological study explored the lived experiences of 11 cross-cultural parents raising children in the U.S., with a focus on how intersecting identities and systemic forces shape parenting practices.

Guided by Critical Multiracial Theory and Intersectionality Theory, this study investigated parenting at the personal, familial, societal, and structural levels. Data were collected through semi-structured interviews and analyzed …

Tumor-Specific Surface Marker–Independent Targeting Of Tumors Through Nanotechnology And Bioorthogonal Glycochemistry, Hyesun Hyun, Bo Sun, Mostafa Yazdimamaghani, Albert Wielgus, Yue Wang, Stephanie Ann Montgomery, Tian Zhang, Jianjun Cheng, Jonathan S. Serody, Andrew Z. Wang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Biological targeting is crucial for effective cancer treatment with reduced toxicity but is limited by the availability of tumor surface markers. To overcome this, we developed a nanoparticle-based (NP-based), tumor-specific surface marker–independent (TRACER) targeting approach. Utilizing the unique biodistribution properties of NPs, we encapsulated Ac4ManNAz (Maz) to selectively label tumors with azide-reactive groups. Surprisingly, while NP-delivered Maz was cleared by the liver, it did not label macrophages, potentially reducing off-target effects. To exploit this tumor-specific labeling, we functionalized anti–4-1BB Abs with dibenzo cyclooctyne to target azide-labeled tumor cells and activate the immune response. In syngeneic B16F10 melanoma and orthotopic 4T1 …

Risky Genes: The Impact Of Social Determinants Of Health On Dna Methylation In Indigenous Communities, Ella Martin

Celebrating Scholarship and Creativity Day (2018-)

Epigenetics is the study of molecular modifications to DNA structure that do not impact the sequence of the DNA itself. This biological study works to link health outcomes later in life with environmental interactions that affect our genetic predispositions. These complex factors can greatly impact longevity and quality of life. DNA methylation is one type of epigenetic mark that happens through natural biological processes. However, this marking has been shown to be detrimental to the process of aging and can be accelerated by harmful exposures such as stress, substance-use, or chemicals in the environment. Exposure to these compounds is exasperated …