Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 30871 - 30900 of 818142

Full-Text Articles in Entire DC Network

Synthesis, Characterization And Studying Mass Spectra And Thermal Analysis For Complexes Of Some Metal Ions And Determining Their Activity As Antioxidants, Fatimah Al-Zahraa Sh. H, Abbas Ali Salih Al-Hamdani Jun 2025

Synthesis, Characterization And Studying Mass Spectra And Thermal Analysis For Complexes Of Some Metal Ions And Determining Their Activity As Antioxidants, Fatimah Al-Zahraa Sh. H, Abbas Ali Salih Al-Hamdani

Baghdad Science Journal

The new azo dye was prepared from the reaction of the diazonium salt derived from 3-aminophenol with 2-hydroxyquinoline, then it was used to prepare a series of complexes with the chlorides of cobalt, chromium, copper, nickel, platinum, palladium and ammonium molybdate. The ligand was identified by a proton and carbon nuclear magnetic resonance spectroscopy, and the compounds were collected. The prepared materials were subjected to infrared, ultraviolet-visible, and mass spectrometry, as well as thermogravimetric analysis, differential calorimetry, and elemental analysis. Conductivity, magnetic susceptibility, metal content, and chlorine content of the complexes were also measured. The results showed that the ligand …


Photocatalytic Degradation Of Acid Yellow 25 Using Nanoparticle Tio2 Mediated Petai Pod Extract, Anthoni Batahan Aritonang, Reza Audina Putri, Vivi Sisca, Mohammad Jihad Madiabu, Khoiriah Khoiriah Jun 2025

Photocatalytic Degradation Of Acid Yellow 25 Using Nanoparticle Tio2 Mediated Petai Pod Extract, Anthoni Batahan Aritonang, Reza Audina Putri, Vivi Sisca, Mohammad Jihad Madiabu, Khoiriah Khoiriah

Baghdad Science Journal

Nanotechnology has significant advantages over traditional methods for degrading dyes. Plant-based nanoparticles were generated apart from other biomaterials. This work employed a green sol-gel approach to prepare titanium dioxide nanoparticles by using Petai (Parkia speciosa) peel extract. The produced TiO2 was analyzed by XRD, UV-DRS, FE-SEM, FTIR, Raman, zeta, and nanoparticle size analysis. PP-TiO2 nanoparticles having a tetragonal anatase phase, spherical, stable particles, and a small particle size (16–22 nm) were successfully produced. When exposed to UV light, the nanoparticles displayed strong photocatalytic activity, eliminating Acid Yellow 25 in less than 120 minutes. This work demonstrates …


Synthesis And Antioxidant Evaluation Of Urea, Carbamate, And Triazole Derivatives Of (2-(6-Methoxynaphthalen-2-Yl) Propanoyl) Glycinoyl Azide, Jihan A. Mustafa, Huda A. Basheer, Parween H. Saleem Jun 2025

Synthesis And Antioxidant Evaluation Of Urea, Carbamate, And Triazole Derivatives Of (2-(6-Methoxynaphthalen-2-Yl) Propanoyl) Glycinoyl Azide, Jihan A. Mustafa, Huda A. Basheer, Parween H. Saleem

Baghdad Science Journal

In this study, a novel series of compounds, derived from the drug naproxen, was synthesized, this series includes carbamates, ureas, semicarbazides, and 1,2,4-triazole derivatives, and the synthesis was achieved through a multi-step synthetic approach. Initially, hydrazide (1) was prepared by reacting naproxen amino acid ester with hydrazine hydrate, followed by its conversion to naproxen glycine azide (2) through treatment with sodium nitrite in hydrochloric acid. Azide (2) was then subjected to thermal decomposition via Curtius rearrangement to yield isocyanate (3). Isocyanate (3) was subsequently reacted with various reagents, such as water, alcohol, amine, concentrated hydrochloric acid, hydrazine, and naproxen hydrazide, …


Synthesis And Biological Study Of Schiff–Mannich Base Derived From 2-Mercaptobenzimidazole As Chelated Tridentate Ligand With Some Transition Metal Ions Complexes, Thuraya Q. Sabah, Shaymaa R. Baqer Jun 2025

Synthesis And Biological Study Of Schiff–Mannich Base Derived From 2-Mercaptobenzimidazole As Chelated Tridentate Ligand With Some Transition Metal Ions Complexes, Thuraya Q. Sabah, Shaymaa R. Baqer

Baghdad Science Journal

To prepare a new ligand, many compounds were used to synthesize Schiff-Mannich base, such as isatin, Para chloro Aniline, 2-mercaptobenzimidazole and indole. The resulting compound 1-((2-((1H-indol-1-ylthio)-1H-benzo[d]imidazol-1-yl)methyl)-3-(4-chlorophenylimino)indolin-2-one (L). (L) was used to create a series of metal ion complexes with Co (II), Ni (II), Cu (II), Pd (II), Pt (IV), and Au (III). C.H.N.S., FTIR, mass spectra UV-ViS, 1H-NMR, 13CNMR, magnetic moment, and molar conductivity were used to characterize all of these compounds. Except for the palladium(II) and gold(III) complexes, all of the produced complexes had an octahedral geometry, according to the data. The antibacterial activity of the produced compounds was …


Feed It To The Ocean: The Federal Approach To Decommissioning In Alaska Native Climate Adaptation Projects, Sophia Tidler Jun 2025

Feed It To The Ocean: The Federal Approach To Decommissioning In Alaska Native Climate Adaptation Projects, Sophia Tidler

Alaska Law Review

This Note calls on the Council on Environmental Quality (CEQ) to issue guidance clarifying that concurrent decommissioning is an in-scope “connected action” under the National Environmental Policy Act for relocation, managed retreat, and protect-in-place projects aimed at replacing infrastructure in environmentally threatened Alaska Native communities. In 2018, the Denali Commission completed the Final Environmental Impact Statement for Alaska’s first community-driven village relocation of the millennium, facilitating construction of essential infrastructure at Mertarvik, the relocation site for the village of Newtok. However, the Denali Commission chose to exclude a full-scale decommissioning plan for Newtok’s existing infrastructure. Today, more than seventy-three Alaska …


The Future Of Alaska’S Wetlands In A Post-Sackett World, Johanna Crisman Jun 2025

The Future Of Alaska’S Wetlands In A Post-Sackett World, Johanna Crisman

Alaska Law Review

In 2023, the United States Supreme Court decided Sackett v. Environmental Protection Agency, which effectively restricted the United States Army Corps of Engineers’ (“USACE”) and the Environmental Protection Agency’s (EPA) ability to regulate development of wetlands. The State of Alaska submitted an amicus brief to the Court on behalf of the petitioners, the Sackett family. In the wake of the decision, Governor Dunleavy praised the decision by the Court, emphasizing that the decision provided the state more autonomy over its own wetlands. Still, there is concern by environmentalists that the State does not have the resources to protect the wetlands …


Integrative Taxonomy Confirms The Synonymy Of Three Springsnail Species (Hydrobiidae: Pyrgulopsis), Kathryn E. Perez, Megan Solis, Michelle Flores, Chanté Lundskog Jun 2025

Integrative Taxonomy Confirms The Synonymy Of Three Springsnail Species (Hydrobiidae: Pyrgulopsis), Kathryn E. Perez, Megan Solis, Michelle Flores, Chanté Lundskog

School of Integrative Biological & Chemical Sciences Faculty Publications

The small, spring-dwelling snails, Pyrgulopsis Call & Pilsbry, 1886, form a diverse radiation in Western North America. In this study, we examine the validity of three species of Pyrgulopsis, Pyrgulopsis pilsbryana (Baily & Baily, 1952), P. nonaria Hershler, 1998, and P. transversa Hershler, 1998. These three species of Pyrgulopsis are found primarily in Utah, with ranges extending into Idaho, Wyoming, and Nevada. They were originally diagnosed primarily on the number and position of penial glands, but subsequent examination with mitochondrial DNA data suggested they should be synonymized. Here, we incorporate additional mitochondrial and nuclear DNA data, increased geographic sampling, …


Green Synthesis, Characterization, Antimicrobial And Anticancer Studies Of Vanadium Oxide Nanoparticles Using Vitex Agnus Castus Extract, Saba H. Mahdi, Lekaa K. Abdul Karem Jun 2025

Green Synthesis, Characterization, Antimicrobial And Anticancer Studies Of Vanadium Oxide Nanoparticles Using Vitex Agnus Castus Extract, Saba H. Mahdi, Lekaa K. Abdul Karem

Baghdad Science Journal

This study, vanadium oxide nanoparticles were synthesized using the biosynthesis method. The resulting VO2 NPs are characterized by their cost-effectiveness, ease of use, and safety. Vanadium Nano oxide was prepared from vanadium sulfate monohydrate with a plant extract of Vitex agnus castus at a sodium hydroxide concentration of 0.1 M. The reaction was carried out in an alkaline medium at pH range of 8–12, which were characterized by using many techniques such as; Fourier transform IR spectroscopy, ultraviolet-visible spectroscopy, x-ray diffraction XRD, transmission electron microscopy TEM, scanning electron microscopy SEM and EDX pattern. The crystal size of nanoparticles, determined …


Potential Epigenetic Impacts Of Phytochemicals On Ruminant Health And Production: Connecting Lines Of Evidence, Sebastian P. Schreiber, Juan Villalba, Mirella L. Meyer-Ficca Jun 2025

Potential Epigenetic Impacts Of Phytochemicals On Ruminant Health And Production: Connecting Lines Of Evidence, Sebastian P. Schreiber, Juan Villalba, Mirella L. Meyer-Ficca

Wildland Resources Student Research

The once mysterious “dark matter of nutrition”, comprising countless plant derived secondary compounds, also known as phytochemicals, is now understood to have significant and wide-ranging effects on consumers, including myriad health benefits in humans and livestock. The selective consumption of phytochemically rich and diverse plants, in appropriate doses, by ruminants represents an adaptive means of therapeutic and prophylactic self-medication. Due to their chemical structure, phytochemicals have long been recognized as antioxidants. However, the mechanisms that underlie numerous additional phytochemical-based health benefits are generally less understood. These effects (i.e., anti-inflammatory, immunomodulatory, and anticarcinogenic effects) are likely related to epigenetic processes. Evidence …


Slow-Growing Lung Mass In A Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor, Ramin Talebi, Charalambos C. Solomides, Nathaniel R. Evans Iii, Gregory C. Kane Jun 2025

Slow-Growing Lung Mass In A Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor, Ramin Talebi, Charalambos C. Solomides, Nathaniel R. Evans Iii, Gregory C. Kane

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

A 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging following successful basilar segmentectomy with mediastinal lymphadenectomy. Pulmonary carcinoid tumor (PCT) is a rare neoplasm in patients with MEN 1, but there is limited data on trends in atypical versus typical carcinoid tumors in these patients. This case emphasizes the need to characterize these trends given the implications for metastatic potential and 5-year survival, which can help guide …


The Effect Of Dbd-Non Thermal Plasma On Oxidative Stress And Tac In Patients With Hcv Infection, Salima K. Ahmed, Salwa H. N. Al- Rubae’I, Hamid H. Murbat, Mazin R. Mohammed Jun 2025

The Effect Of Dbd-Non Thermal Plasma On Oxidative Stress And Tac In Patients With Hcv Infection, Salima K. Ahmed, Salwa H. N. Al- Rubae’I, Hamid H. Murbat, Mazin R. Mohammed

Baghdad Science Journal

Non-thermal plasma (NTP) is a processing technique that is widely-spread in different biological and medical application which stimulates or inhibits cellular processes through releasing reactive oxygen and nitrogen species (ROS and RNS, respectively) in biological systems. In this study, it was investigated that the impact of NTP on oxidative stress and antioxidant capacity markers, as well as the effect of NTP on the copy number of Hepatitis C virus (HCV RNA). Dielectric barrier discharge (DBD) plasma was used to generate the NTP. The results showed that the exposure of HCV specimen to NTP causes oxidative stress, RNA damage, Protein denaturation, …


Changes In Aggressive Behaviors Over Time In Children With Adverse Childhood Experiences: Focusing On The Role Of School Connectedness, Sei-Young Lee, Mijin Choi Jun 2025

Changes In Aggressive Behaviors Over Time In Children With Adverse Childhood Experiences: Focusing On The Role Of School Connectedness, Sei-Young Lee, Mijin Choi

Faculty Publications

Previous research has found the link between adverse childhood experiences (ACEs) and externalizing behaviors later in adolescence and adulthood. However, limited studies have explored longitudinal trajectories of aggressive behaviors affected by ACEs. This study aimed to investigate how aggressive behaviors change over time and compare the trajectories of aggressive behaviors between children with three or fewer (low-risk ACEs) and those with four or more ACEs (high-risk ACEs) with the role of school connectedness on the trajectories of aggressive behaviors over time. The study sample consisted of 4231 children collected by the Future of Families and Child Wellbeing Study, a longitudinal …


Implications Of Neural Compression To Scientific Images, João Phillipe Cardenuto, Joshua Krinsky, Lucas Nogueira, Aparna Bharati, Daniel Moreira Jun 2025

Implications Of Neural Compression To Scientific Images, João Phillipe Cardenuto, Joshua Krinsky, Lucas Nogueira, Aparna Bharati, Daniel Moreira

Computer Science: Faculty Publications and Other Works

While neural compression has the potential to revolutionize image compression, recent studies have emphasized its ability to introduce subtle artifacts that could alter the image content. Concerned about the impact of such modifications on scientific images, this work explores the potential effects of neural compression on these images, focusing on two critical aspects: semantic understanding and forensic integrity. We use scientific image datasets to assess the performance of neural compression techniques on Visual Question Answering (VQA) and copy-move forgery detection tasks. Our findings indicate that the subtle changes introduced by neural ] compression do not significantly degrade the performance of …


Proteogenomic Analysis Of The Calgb 40601 (Alliance) Her2+ Breast Cancer Neoadjuvant Trial Reveals Resistance Biomarkers, Eric J Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi D Vashist, Matthew V Holt, Laterrica Williams, Jonathan T Lei, Chang In Moon, Beom-Jun Kim, Yongchao Dou, Haoquan Zhao, Viktoriya Korchina, Richard A Gibbs, Donna Marie Muzny, Harshavardhan Doddapaneni, Charles M Perou, Lisa A Carey, Ana I Robles, Terry Hyslop, Yujia Wen, Linda Mccart, Azra Krek, Francesca Petralia, George Miles, Shyam M Kavuri, Michael A Gillette, D R Mani, Steven A Carr, Bing Zhang, Matthew J Ellis, Shankha Satpathy, Meenakshi Anurag Jun 2025

Proteogenomic Analysis Of The Calgb 40601 (Alliance) Her2+ Breast Cancer Neoadjuvant Trial Reveals Resistance Biomarkers, Eric J Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi D Vashist, Matthew V Holt, Laterrica Williams, Jonathan T Lei, Chang In Moon, Beom-Jun Kim, Yongchao Dou, Haoquan Zhao, Viktoriya Korchina, Richard A Gibbs, Donna Marie Muzny, Harshavardhan Doddapaneni, Charles M Perou, Lisa A Carey, Ana I Robles, Terry Hyslop, Yujia Wen, Linda Mccart, Azra Krek, Francesca Petralia, George Miles, Shyam M Kavuri, Michael A Gillette, D R Mani, Steven A Carr, Bing Zhang, Matthew J Ellis, Shankha Satpathy, Meenakshi Anurag

Faculty, Staff and Students Publications

Proteogenomic analysis is applied to samples from the CALGB 40601 (Alliance) randomized neoadjuvant trial of trastuzumab, lapatinib, or the combination to identify biomarkers associated with pathological response status. Absence of ERBB2 gene amplification and human epidermal growth factor receptor 2 (HER2) protein overexpression by proteogenomics is associated with non-pathological compete response (pCR) (p < 0.05), highlighting potential false positives from standard diagnostics. Pathway analysis in proteogenomics-confirmed HER2+ samples identifies elevated epithelial-mesenchymal transition (EMT) and WNT-β-catenin signaling in non-pCR cases before treatment. Twenty-four pCR-associated proteins reproduce in a second proteomic dataset, and four (GPRC5A, TPBG, SP140L, and NEU1) are significant in a third. A meta-analysis of ten diverse neoadjuvant anti-HER2 treatment regimens from four independent studies confirms that non-pCR cases express higher levels of mRNA for G protein-coupled receptor class C group 5 member A (GPRC5A, p = 0.0002) and trophoblast glycoprotein (TPBG, p = 0.00008). Thus, proteogenomic analysis identifies negative biomarkers for pCR and alternative plasma membrane targets for treatment-resistant HER2+ breast cancer.


Btp2 Restricts Tulane Virus And Human Norovirus Replication Independent Of Store-Operated Calcium Entry, Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Jorge Villanueva, Son Pham, Soni Kaundal, Janam J Dave, B V Venkataram Prasad, Mary K Estes, Sasirekha Ramani, Joseph M Hyser Jun 2025

Btp2 Restricts Tulane Virus And Human Norovirus Replication Independent Of Store-Operated Calcium Entry, Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Jorge Villanueva, Son Pham, Soni Kaundal, Janam J Dave, B V Venkataram Prasad, Mary K Estes, Sasirekha Ramani, Joseph M Hyser

Faculty, Staff and Students Publications

Human norovirus is the leading cause of viral gastroenteritis across all age groups. While there is a need for human norovirus antivirals, therapeutic development has been hindered by a lack of cell culture systems and animal models of infection. Surrogate viruses, such as Tulane virus (TV), have provided tractable systems to screen potential antiviral compounds. Our previous work demonstrated that TV encodes a viral ion channel, which dysregulates cytosolic calcium signaling. We set out to investigate whether host pathways triggered by viral ion channel activity, including store-operated calcium entry (SOCE), play a role in virus replication. Using pharmacologic inhibitors and …


Dosimetric Advantage Of Scanning Beam Proton Therapy In Gynecologic Patients Receiving Adjuvant Radiotherapy, Rachel B Ger, Jarrod M Lentz, Joshua S Niedzielski, Sujay A Vora, Martin Bues, Danairis Hernandez Morales, Justin D Anderson, Christopher J Kutyreff, Christie A Schulz, Pedro R Lara, Ana K Ridgway, Pamela R Lemish, Justin D Gagneur, Aman Anand Jun 2025

Dosimetric Advantage Of Scanning Beam Proton Therapy In Gynecologic Patients Receiving Adjuvant Radiotherapy, Rachel B Ger, Jarrod M Lentz, Joshua S Niedzielski, Sujay A Vora, Martin Bues, Danairis Hernandez Morales, Justin D Anderson, Christopher J Kutyreff, Christie A Schulz, Pedro R Lara, Ana K Ridgway, Pamela R Lemish, Justin D Gagneur, Aman Anand

Faculty, Staff and Student Publications

Background/Objectives: Adjuvant radiation for gynecologic malignancies often exposes organs at risk (OARs), such as the bone marrow, bowel, rectum, and bladder, to radiation, leading to toxicities that impact treatment tolerance and patient quality of life. Scanning proton beam therapy, particularly with Individual Field Simultaneous Optimization (IFSO), may offer dosimetric and biological advantages over volumetric modulated arc therapy (VMAT). This study evaluates the clinical impact of IFSO-based proton planning in post-operative gynecologic cancer patients.

Materials and Methods: Fourteen patients receiving adjuvant proton therapy to 45 Gy in 25 fractions were retrospectively analyzed. Comparison VMAT plans were generated on the same datasets. …


Identification Of Hypoxia-Inducible Factor Hif1a As A Therapeutic Target During Sars-Cov-2-Associated Lung Injury, Bentley Bobrow, Samuel D Luber, Paul Potnuru, Katherine Figarella, Jieun Kim, Yanyu Wang, In Hyuk Bang, David Robinson, Paulina B Sergot, Steven K Burke, Tingting Mills, Constanza De Dios, Robert Suchting, George W Williams, Adit A Ginde, Yafen Liang, Hongfang Liu, Charles Green, Marie-Francoise Doursout, Alparslan Turan, Daniel I Sessler, Xiaoyi Yuan, Holger K Eltzschig Jun 2025

Identification Of Hypoxia-Inducible Factor Hif1a As A Therapeutic Target During Sars-Cov-2-Associated Lung Injury, Bentley Bobrow, Samuel D Luber, Paul Potnuru, Katherine Figarella, Jieun Kim, Yanyu Wang, In Hyuk Bang, David Robinson, Paulina B Sergot, Steven K Burke, Tingting Mills, Constanza De Dios, Robert Suchting, George W Williams, Adit A Ginde, Yafen Liang, Hongfang Liu, Charles Green, Marie-Francoise Doursout, Alparslan Turan, Daniel I Sessler, Xiaoyi Yuan, Holger K Eltzschig

Faculty, Staff and Student Publications

Hypoxia-inducible factors (HIFs) promote lung protection and pathogen eradication during acute lung injury. We therefore tested the theory that pharmacologic stabilization of HIFs dampens lung injury during SARS-CoV-2 pneumonia. Initial studies in murine SARS-CoV-2 models showed improved outcomes after treatment with the FDA-approved HIF-stabilizer vadadustat. Subsequent studies in genetic models implicated alveolar-expressed Hif1a in mediating lung protection. Therefore, we performed a randomized, double-blinded, multicenter phase 2 trial in patients admitted for SARS-CoV-2 infection and concomitant hypoxia (SpO2 ≤ 94%). Patients (n=448) were randomized to oral vadadustat (900 mg/day) or placebo for up to 14 days. Safety events were similar between …


Synthesis, Antibacterial Evaluation, And Prediction Of The Ability Of Corrosion Inhibition By Density Functional Theory Of Azo-Dyes Of Folic Acid, Athra G. Sager, Jawad Kadhim Abaies, Aseel F. Abdullah Jun 2025

Synthesis, Antibacterial Evaluation, And Prediction Of The Ability Of Corrosion Inhibition By Density Functional Theory Of Azo-Dyes Of Folic Acid, Athra G. Sager, Jawad Kadhim Abaies, Aseel F. Abdullah

Baghdad Science Journal

In this study, new folic acid (B9) derivatives (a–d) were synthesized by reacting diazonium salt (of folic acid) with different aromatic compounds including 1-naphthol, 2-naphthol, pyrocatechol, or resorcinol. One of Schiff bases (I) was prepared by reacting folic acid with 4-amino benzaldehyde. Then, azo compound (e) was synthesized by coupling Schiff base with 1-naphthol. The new azo compounds (a–e) were identified by FTIR, 1HNMR spectroscopy, and by measurements of some physical properties. The current work investigated the physical characteristics of compounds (a–e) in order to select the best corrosion inhibitor. 6-311G+/(d, p) base set and Density Functional …


Nutrient Dynamics In Restored And Unrestored Urban Streams In The Piedmont Ecoregion Of South Carolina, Emily J. Jordan, Debabrata Sahoo, Calvin B. Sawyer, Jeremy W. Pike, Dara M. Park, Sarah A. White, Brian E. Haggard Jun 2025

Nutrient Dynamics In Restored And Unrestored Urban Streams In The Piedmont Ecoregion Of South Carolina, Emily J. Jordan, Debabrata Sahoo, Calvin B. Sawyer, Jeremy W. Pike, Dara M. Park, Sarah A. White, Brian E. Haggard

Biological and Agricultural Engineering Faculty Publications and Presentations

The United States invests billions of dollars annually to perform stream restoration projects, yet few studies have investigated the effects this ecosystem manipulation has on nutrient cycling and associated water quality. Water quality improvement remains a substantial motivation for mitigating catchment-scale disturbances, especially in urban streams. Various urban land use practices impact the transfer and transport of nutrients such as soluble reactive phosphorus, ammonium, and nitrate plus nitrite from land into the streams and rivers. The uptake length (Sw), or the distance a dissolved nutrient travels downstream within a stream reach, can be measured using short-term nutrient injections, where shorter …


Effectiveness Of Digital Behavioral Activation Interventions For Depression And Anxiety: Systematic Review And Meta-Analysis, Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham Jun 2025

Effectiveness Of Digital Behavioral Activation Interventions For Depression And Anxiety: Systematic Review And Meta-Analysis, Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham

2020-Current year OA Pubs

BACKGROUND: As digital interventions gain prominence in mental health care, they present opportunities to improve access and scalability. Despite their potential, the overall impact of digital behavioral activation (BA) interventions across different formats and populations is not yet fully understood.

OBJECTIVE: This systematic review examines the characteristics and functions of digital BA interventions and evaluates their effectiveness for mental health and other patient-related outcomes.

METHODS: A comprehensive search of databases (PubMed, Embase, Web of Science, APA PsycInfo, and ClinicalTrials.gov) was performed in November 2023 to identify randomized controlled trials (RCTs) assessing the effectiveness of digital BA interventions for depression and …


Ldl Receptor-Mediated Endocytosis Of Escherichia Coli Α-Hemolysin Mediates Renal Epithelial Toxicity, Hunter W Kuhn, Madeleine R Smither, Rachel J Jin, Christina A Collins, Hongming Ma, Jason Sina, Joseph P Gaut, Michael S Diamond, David A Hunstad Jun 2025

Ldl Receptor-Mediated Endocytosis Of Escherichia Coli Α-Hemolysin Mediates Renal Epithelial Toxicity, Hunter W Kuhn, Madeleine R Smither, Rachel J Jin, Christina A Collins, Hongming Ma, Jason Sina, Joseph P Gaut, Michael S Diamond, David A Hunstad

2020-Current year OA Pubs

The α-hemolysin (HlyA) of uropathogenic


Advances In Molecular Imaging For Neuroendocrine Neoplasms, Bradley Girod, Vikas Prasad Jun 2025

Advances In Molecular Imaging For Neuroendocrine Neoplasms, Bradley Girod, Vikas Prasad

2020-Current year OA Pubs

Neuroendocrine neoplasms (NENs) represent a heterogenous group of tumors with significant inter- and intra-patient variability. Once considered to be rare, neuroendocrine neoplasms are being increasingly recognized through the advent of advanced diagnostic techniques, which may be contributing to the significant increase in the incidence and detection rate of these tumors. NENs can be classified into well differentiated and poorly differentiated neuroendocrine tumors (NETs) or neuroendocrine carcinomas (NECs). The proliferation rate of NETs can vary from Ki-67 1-55%. In addition, the SSTR expression can vary significantly. Because of this high "heterogeneity", their detection and characterization have become essential to disease management, …


Rethinking The Philosophy Of Religion: Toward A Better Relationship Between Religion And Science, Jovino De Guzman Miroy Jun 2025

Rethinking The Philosophy Of Religion: Toward A Better Relationship Between Religion And Science, Jovino De Guzman Miroy

Budhi: A Journal of Ideas and Culture

This paper rethinks the philosophy of religion by asking what it can learn from the less antagonistic and more dialogic relationship between science and religion. Greater heterogeneity amongst student beliefs requires that the philosophy of religion become pluralistic. Moving beyond antagonism, the task of the philosophy of religion is to improve the relationship between religion and science for the better. The paper also probes what it means to study religion scientifically. The reform of the philosophy of religion proposed here means that the field shed its apologetic nature, but continue its project of reason-giving for a synthesis of religious experience. …


How The Immediate Physical Environment Affects The Non-Physical Aspect Of Health, Katryn Noelle E. Valeriano Jun 2025

How The Immediate Physical Environment Affects The Non-Physical Aspect Of Health, Katryn Noelle E. Valeriano

Budhi: A Journal of Ideas and Culture

Human health has been closely intertwined with environmental health. By the term “environment,” I refer not only to nature or relationships found in an ecosystem but also to the immediate physical milieu of an individual or what is termed as “personal space.” Before the pandemic, the notion of personal space was more fluid and receptive due to the ease one had in “re-framing” the environment and reorienting oneself. However, during the pandemic, the personal space of humans was restricted in so many ways through lockdowns and various forms of isolation. This article intends to re-interpret concepts, such as of “physical …


Professional Sport Venue Threats, Security Measures, And Technological Solutions, Brandon Allen, Laurajean Holmgren, Stacey A. Hall Jun 2025

Professional Sport Venue Threats, Security Measures, And Technological Solutions, Brandon Allen, Laurajean Holmgren, Stacey A. Hall

Global Sport Business Journal

Several incidents involving large crowds have led venue security directors to adopt preventive strategies. Venue organizers should foster a safe and secure environment, which requires assessing risk levels, recruiting and training staff, exercising plans and protocols, and leveraging technology solutions. The purpose of this study is to explore professional sport venue threats, security measures, and technology utilization. Security directors (n=52) from five major sports leagues in the United States (MLB, MLS, NBA, NFL, and NHL) participated in the study. Key findings focus on staffing, training and development, fan behavior, and facility operations. Recommendations include investing in multiple strategies to enhance …


Using Lrr Standard Deviation As A Genotype Quality Control Measure And Its Downstream Effect On Cnv Calling., Adam Dunne Jun 2025

Using Lrr Standard Deviation As A Genotype Quality Control Measure And Its Downstream Effect On Cnv Calling., Adam Dunne

ORBioM (Open Research BioSciences Meeting)

Background:

Log R Ratio (LRR) is a genotype intensity measurement returned alongside routine genotype results and used to detect structural variation in the genome known as copy number variation (CNVs). Although LRR standard deviation (SD) is commonly applied as a quality control measure in CNV studies, limited research has explored its effect on genotype quality and the potential impact on CNV calling.

Methods:

A total of 720,152 genotypes were available on 716,234 cattle. Among these were 1,044 cattle that had duplicate genotype samples where one sample was considered gold standard (LRR SD < 0.3, Call Rate ≥ 0.95). Genotype concordance was calculated for all duplicates. PennCNV was used to call CNVs and concordance among CNV calls per duplicate animal was determined using the Jaccard index.

Results:

Across all 720,152 cattle samples, the mean …


Environmental Screening For Multidrug Resistant (Mdr) Organisms In The Surgical Ward Of An Irish Tertiary Referral Hospital., Sinead A. Fahy, Sinéad Fahy Jun 2025

Environmental Screening For Multidrug Resistant (Mdr) Organisms In The Surgical Ward Of An Irish Tertiary Referral Hospital., Sinead A. Fahy, Sinéad Fahy

ORBioM (Open Research BioSciences Meeting)

The aim of the current study was to determine the prevalence of Multidrug Resistant Organisms (MDRO) colonisation on a surgical ward of an acute tertiary hospital. MDRO determination was conducted on a patient-occupied surgical ward over a 6-month period. The screen included sink, and shower drains in bathrooms and sinks of multi-bedded and single-occupied rooms. Swabs were cultured on chromogenic agar to enable detection of methicillin resistant Staphylococcus aureus (MRSA), Carbapenemase producing enterobacterales (CPE), Vancomycin Resistant Enterococci (VRE) and Extended spectrum beta-lactamase (ESBL). Suspect resistant organisms were confirmed using NG-Carba 5 (NG Biotech, Guipry, France) lateral flow tests, Vitek 2.0 …


Artificial Intelligence And Privacy, Daniel J. Solove Jun 2025

Artificial Intelligence And Privacy, Daniel J. Solove

Florida Law Review

This Article aims to establish a foundational understanding of the intersection between artificial intelligence (AI) and privacy, outlining the current problems AI poses to privacy and suggesting potential directions for the law’s evolution in this area. Thus far, few commentators have explored the overall landscape of how AI and privacy interrelate. This Article seeks to map that territory.

Some commentators question whether privacy law is appropriate for addressing AI. In this Article, I contend that although existing privacy law falls far short of resolving the privacy problems with AI, privacy law properly conceptualized and constituted would go a long way …


Examining The Impact Of Stress On Collegiate Flight Students, Shivanee D. Cannon-Patron Jun 2025

Examining The Impact Of Stress On Collegiate Flight Students, Shivanee D. Cannon-Patron

Beyond: Undergraduate Research Journal

Stress may negatively affect the timely completion of a student pilot's flight training. A student pilot influenced by stress may be subject to what is known as "falling behind the aircraft," a condition that constantly requires minor interventions from their flight instructor. This lack of situational awareness and decreased performance may inadvertently cause the student pilot to repeat the flight lesson, increasing the time spent in the training course.


Examining The Anxiolytic Effects Of Flavonoids In Passionflower: A Gut-Brain Axis Perspective, Khelen R. Walsh Jun 2025

Examining The Anxiolytic Effects Of Flavonoids In Passionflower: A Gut-Brain Axis Perspective, Khelen R. Walsh

PSU McNair Scholars Online Journal

This literature review investigates the influence of Passiflora incarnata on the Gut-Brain Axis, focusing on the role of flavonoids and the specific biological mechanisms involved in this process. The study aims to identify Passiflora incarnata as a practical, non-harmful, and cost-effective alternative to current modern anxiety medications. This study also emphasizes the need for further clinical trials to integrate Passiflora incarnata further into healthcare settings. Using a narrative review approach, this analysis will examine pre-existing empirical articles, all of which have been found on credible sites, are peer-reviewed, and have been published within the past twenty-five years. The data discussed …