Digital Commons Network^™

From Policy To Pedagogy: Applying Infodemic Governance To Instructional Design, Bethany S. Mcgowan

Libraries Faculty and Staff Scholarship and Research

This article presents a Delphi study that defines key ethical and regulatory principles underpinning Finland’s national strategy for managing infodemics. Drawing on three rounds of consultation with Finnish experts from health, policy, and library sectors, the study surfaces foundational elements of national infodemic management—including transparency, accountability, inclusion, and adaptability—as well as gaps in digital equity, curricular responsiveness, and cross-sector collaboration. These expert-defined priorities are analyzed alongside the World Health Organization’s Infodemic Management Agenda, which serves as a pedagogical scaffold for identifying instructional tensions in health information literacy education. Findings are further interpreted through four information diplomacy anchors: agenda-setting, persuasive framing, …

Independence Beyond Sight: Occupational Therapy's Role In Promoting Functional Independence In Low Vision Communities, Kristina Holcomb

Occupational Therapy Student Capstones

Many individuals with low vision experience a multitude of barriers limiting access to community and healthcare services. Interviews highlighted the need to expand outreach to youth, build an updated community resource guide, and the need for community events for all programs.

Enhancing Health Literacy Among Spanish-Speaking Individuals With Parkinson’S Disease, Christie Ledezma

Occupational Therapy Student Capstones

Parkinson’s disease may be significantly under-represented and inadequately treated in rural areas, specifically in the Spanish-speaking community due to lower health literacy levels and limited resources. Project: Determine barriers faced by Spanish-speaking individuals with Parkinson’s disease and implement into solutions.

From Plan To Practice: Enhancing Lifestyle Management Through Effective Carry Over Strategies Using Occupational Therapy Perspective, Josephine Hernandez

Occupational Therapy Student Capstones

Explore and build on existing knowledge of occupational therapy’s role in lifestyle management techniques through embodied experience. Explore evidence-based research on embodied interventions with multidisciplinary care. Explore and exercise advocacy skills within a multidisciplinary team. Explore and apply marketing and outreach initiatives for increased community awareness of resources.

Acute Toxicity Of Arsenate And Arsenite In Two Scleractinian Coral Species: Acropora Cervicornis And Orbicella Faveolata, Cailey Dorman

All HCAS Student Capstones, Theses, and Dissertations

Inorganic arsenic (As), specifically arsenate (As(V)) and arsenite (As(III)) are well-documented toxicants to a range of marine organisms. However, their specific impacts on coral reef species remain largely unstudied. This study is the first to assess the acute and subacute toxicity of inorganic arsenic on two threatened scleractinian coral species, Acropora cervicornis and Orbicella faveolata. Corals were exposed for 96 hours to five analytically verified concentrations and a negative control of either arsenate or arsenite. Toxicity was evaluated through three endpoints: mortality (LC50), coral condition (EC50), and photosynthetic efficiency (IC50). The lethal concentrations to result in 50% mortality (LC50) …

Immediate-Use Rescue Medication And The Epilepsy Monitoring Unit: Experiences From An Expert Panel, Evelyn K. Shih, Brin E. Freund, Michael R. Sperling, Danielle A. Becker, Proleta Datta, Sandra Dewar, Edward Faught, Tracy Glauser, R. Edward Hogan, Randa Jarrar, Andres M. Kanner, David King-Stephens, Rebecca E. Matthews, Patricia Penovich, M. Scott Perry, Eric B. Segal, Joseph Sirven, John M. Stern, James W. Wheless, Enrique Carrazana, Adrian L. Rabinowicz, William O. Tatum

Department of Neurology Faculty Papers

BACKGROUND: People with epilepsy (PWE) may experience seizure clusters, broadly defined as ≥2 seizures that occur in close proximity. In epilepsy monitoring units (EMUs), seizure clusters can spontaneously occur during long-term videoelectroencephalogram monitoring (LTVEM) or as a result of antiseizure medication dose adjustments. In this survey, we examined the experiences and practices of expert clinicians with seizure clusters in EMUs.

METHODS: A 55-item survey was sent to members of an Epilepsy Education Council who are epilepsy experts. Items described experiences, treatment practices, and negative outcomes with seizure clusters in EMUs.

RESULTS: Of the 15 experts (aged 43-77 y), 14 are …

Spatio-Temporal Variability Of San Francisco Bay Plume From Space, Piero L. F. Mazzini, Cassia Pianca, L. Fernando Pareja-Roman, Kelly L. Cole, Ryan K. Walter, Renato M. Castelao, Elias J. Hunter, Robert J. Chant

Physics

As brackish turbid waters exit San Francisco Bay, one of the largest estuaries in the U.S. West Coast, they form the San Francisco Bay Plume (SFBP), which spreads offshore and influences the Gulf of the Farallones (GoF), an ecologically significant region in the California Current System that is also home to three National Marine Sanctuaries. This paper provides the first observationally based investigation of the spatio-temporal variability of the SFBP, using a plume tracking algorithm applied to more than two decades (2002-2023) of ocean color data from the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor onboard satellites Aqua and Terra. The …

Edna Surveillance And Population Genomics Of The Invasive Loaches Introduced To The United States, Tobin J. Davidson

Theses and Dissertations

Invasive species represent a growing threat to the ecosystems and economies of the United States. The southeastern United States is an aquatic biodiversity hotspot, and the decline of multiple native species already facing extinction is attributed to a rapidly growing number of nonindigenous freshwater fishes. Next-generation sequencing was used to analyze the population genomics of several populations of Pond Loach (Misgurnus anguillicaudatus) introduced to the United States. Three evolutionarily significant units of Misgurnus loaches were found, suggesting the invasion of multiple different species in the United States. Additionally, noninvasive environmental DNA (eDNA) protocol designed for early detection of invasive freshwater …

Interspecific Competition Effects On Biomass Allocation In A Young, Fertilized Longleaf Pine Stand In Central Mississippi, Baylor Doughty

Theses and Dissertations

Restoration of longleaf pine (Pinus palustris Mill.) can be challenging on sites with high densities of naturally regenerated loblolly pine (Pinus taeda L.). This study aims to understand how interspecific competition impacts early establishment of planted longleaf pine. The study area was a complete block design to evaluate two different fertilization methods and application of diazotrophic endophytes. While the site was chemically prepared, high densities of loblolly pine established from adjacent stands. Measurements included survival, root collar diameter, height, and neighboring competition. Soil properties, including texture and nitrogen mineralization rates, were also evaluated. Results indicate that fertilization had a significant …

The Interplay Of Biomarkers And Psychosocial Variables In Ipv Perpetration, Arturo L. Cantos, María L. Mondolfi, K. Daniel O'Leary

Psychological Science Faculty Publications

Relevant biopsychosocial factors, including testosterone (T) and cortisol (C) levels, adverse childhood experiences (ACEs), and difficulties in emotion regulation, have been implicated in IPV perpetration. However, further research is needed to clarify how biomarkers and psychosocial variables interact. The authors herein predicted that emotion regulation difficulties would moderate the association between ACES and IPV perpetration. The sample consisted of 30 IPV perpetrators aged 18 to 51 (M = 30.80, SD = 8.43) and 30 control non-perpetrator participants aged 18–35 (M = 24.13; SD = 4.28). All participants provided saliva samples to assess T and C levels and completed a sociodemographic …

Bridging Physics And Machine Learning: Physics-Informed Neural Networks (Pinn) For Wire-Arc Additive Manufacturing (Waam) Thermal Prediction, Haiye (Justin) Xie

Theses and Dissertations

Over the past decade, additive manufacturing (AM) has gained substantial use in industry and research. It is a promising alternative to traditional subtractive and casting manufacturing. AM not only saves time and materials but can also construct intricate structures within components for specific purposes. Wire-Arc Directed Energy Deposition (WA-DED) is one of the additive manufacturing technologies that offers a high extrusion rate of metal wire materials to fabricate near-net-shape metal components. Accurate temperature control is crucial for controlling the microstructure of metal components fabricated through the AM process. Machine learning has the ability to analyze real-time sensor data, such as …

The Effect Of Coadministration Of D156844 And Ar42 (Rec-2282) On The Survival And Motor Phenotype Of Mice With Spinal Muscular Atrophy, Ashlee W. Harris, Rod C. Scott, Matthew E. R. Butchbach

Department of Pediatrics Faculty Papers

Spinal muscular atrophy (SMA) is characterized by degeneration of spinal motor neurons and is a leading genetic cause of pediatric death worldwide. SMA results from the loss of or pathological variant in the survival motor neuron 1 (SMN1) gene. Disease severity is dependent on the number of copies of the orthologous SMN2 gene, which is nearly identical to SMN1 except for some key nucleotide differences. As disease severity is inversely related to SMN2 copy number, most SMA therapeutics trials have focused on identifying ways to increase SMN2 expression at different levels of gene regulation. Other studies have investigated compounds which …

Amputation Trends Among People Who Use Drugs In The Context Of Philadelphia’S Increasingly Xylazine Adulterated Drug Supply, Rose Laurano, Monika Pogorzelska-Maziarz, Traci C. Green, Sara Beachy, Kristin L. Rising, Jeffrey K. Hom, Megan K. Reed

Jefferson Center for Connected Care Faculty Papers

BACKGROUND: Xylazine-adulterated fentanyl has rapidly spread across the United States and has been increasingly detected in overdose deaths in Philadelphia, PA through medical examiner reports, clinical testing, and widescale drug checking. Xylazine use has been associated with wounds which may lead to amputation, but the extent of this outcome has not been explored.

METHODS: Utilizing the 10th revision of the International Classification of Diseases (ICD-10) codes, we conducted a de-identified retrospective analysis of data for patients identified with opioid related disorders (ICD-10 code F11) admitted to four different hospitals in Philadelphia, PA between 2018 and 2023. Exposure to xylazine use …

Tet2-Mutant Myeloid Cells Mitigate Alzheimer’S Disease Progression Via Cns Infiltration And Enhanced Phagocytosis In Mice, Katie A Matatall, Trisha K Wathan, Minh Nguyen, Hu Chen, Alexandra Mcdonald, Guantong Qi, Julia A Belk, Marcus A Florez, Duy T Le, Temitope Olarinde, Caitlyn Vlasschaert, Marco M Buttigieg, Chih-Wei Fan, Saul Carcamo, Ruoqiong Cao, Daniel E Kennedy, Arushana A Maknojia, Apoorva Thatavarty, Josaura V Fernandez Sanchez, Hind Bouzid, Surabi Veeraragavan, Susan Crocker, Margaret A Goodell, Antony Rodriguez, Siddhartha Jaiswal, Michael J Rauh, Eirini P Papapetrou, Samuele G Marro, Katherine Y King

Faculty, Staff and Students Publications

Clonal hematopoiesis (CH) is associated with many age-related diseases, but its interaction with Alzheimer's disease (AD) remains unclear. Here, we show that TET2-mutant CH is associated with a 47% reduced risk of late-onset AD (LOAD) in the UK Biobank, whereas other drivers of CH do not confer protection. In a mouse model of AD, transplantation of Tet2-mutant bone marrow reduced cognitive decline and β-amyloid plaque formation, effects not observed with Dnmt3a-mutant marrow. Bone-marrow-derived microglia-like cells were detected at an increased rate in Tet2-mutant marrow recipients, and TET2-mutant human induced pluripotent stem cell (iPSC)-derived microglia were more phagocytic and hyperinflammatory than …

Histologic And Immune Characterization Of Cutaneous Immune-Related Adverse Events Induced By Immune Checkpoint Inhibitors, Omar Pacha, Anisha B Patel, Jonathan L Curry, Cara L Haymaker, Nejla Ozirmak Lermi, Dzifa Yawa Duose, Ken Chen, Joud Hajjar, Aung Naing

Faculty, Staff and Student Publications

Background: Although immune checkpoint inhibitors (ICIs) are efficacious, they often cause immune-related adverse events (irAEs), most commonly cutaneous irAEs (CirAEs). The mechanisms underlying CirAEs remain unclear.

Methods: Attempting to better understand their mechanisms and histology we conducted a prospective study of 15 patients with advanced cancers treated with ICIs who developed grade 2 or higher CirAEs. Clinical and histologic characterization of biopsy specimens of CirAEs was performed. Histologic analysis of patient biopsy specimens were subdivided by epidermal reaction patterns that included spongiotic, lichenoid, and interface dermatitis patterns. A targeted RNA expression assay was used to identify immune markers in CirAE …

The Trophic Ecology Of The Snipe Eel Avocettina Infans (Anguilliformes: Nemichthyidae) In The Deep-Pelagic Gulf Of Mexico, Emma N. Schindler

All HCAS Student Capstones, Theses, and Dissertations

The Nemichthyidae (snipe eels) are ubiquitous in the deep-pelagic waters of tropical and temperate latitudes, and in some ecosystems are among the dominant fishes. In the deep waters of the Gulf of Mexico, the nemichthyid species Avocettina infans is one of the dominant large predators. This prompted the current study, where an extensive sample set was utilized to characterize the abundance of the family in total, and the vertical distribution and trophic ecology of A. infans specifically. The nemichthyid abundance from 0 – 1500 m was estimated at 1,106.58 individuals per billion cubic meters, the largest portion of which was …

Transcription Fidelity In The Face Of Oxidative Damage, Eastilan Gyiwah Appiah

Theses and Dissertations

It is very important that the process of transcription is correctly carried out in the cell for the faithful expression of the genetic code. However, should mistakes happen, they can result in transcription errors which interfere with the protein-making machinery of the cell. This will result in accumulation of proteins and dysfunctional proteins that have the potential of causing diseases like Alzheimer’s. Oxidative damage caused by hydrogen peroxide is known to cause transcription errors in organisms like yeast. It is therefore important to investigate the extent to which hydrogen peroxide can damage cells.

Fungal Resistance Of Citric Acid Crosslinked Chitosan Treated Wood, Samuel Jacob Barton

Theses and Dissertations

Chitosan (CH), a linear polysaccharide biopolymer derived from chitin, is known for its antimicrobial and antifungal properties. However, its natural hydrophilicity limits its application as a wood preservative. This study explores the crosslinking of chitosan with citric acid (CA) to improve its stability and hydrophobicity, aiming to enhance its efficacy as a wood preservative. The study investigates fungal resistance against Gloeophyllum trabeum (brown-rot) and Trametes versicolor (white-rot) fungi using the AWPA E-10 soil block test for pine and gum samples vacuum-treated and dip-treated with CH-CA concentrations (CH 6%/CA 3%, CH 4%/CA 3%, CH 2%/CA 3%, and CH 1.5%/CA 3%). The …

Determining The Toxic Threshold And Other Use Characteristics For Industrial Hemp Seed Oil Used For Wood Product Protection, Daylan M. Barnes

Theses and Dissertations

Plant-based wood treatments have been utilized for many years, with varying success. Oils such as those extracted from linseed (flax), tung, and hemp plants have been used for thousands of years as finishes on wood. These are all drying oils, which dry to a film when exposed to air. Hemp seed oil has a high fatty acid content and can take a long time to dry on wood products but is valued in woodworking for being easy to use, food-safe, and having little to no odor. In this study, cold-pressed hemp seed oil, blended with a soybean carrier oil, is …

Effects Of Psychological Arousal And Relaxation On Muscle Performance, Activation, And Heart Rate Variability During Maximal Muscle Strength And Precision Tasks, Allison Ann Brown

Theses and Dissertations

Psychological arousal plays a vital role in athletic performance, with the optimal point of arousal and performance level varying by task complexity. A common manipulator of arousal is music, which can produce multiple physiological effects. This study investigated whether unfamiliar arousing or relaxing music influences heart rate variability, muscle activation, maximal muscle strength, and muscle precision. Theoretically, if participants are found to have differing muscle performance responses as a result of differing music selections, this would further support the notion that the optimal point of arousal and performance is dependent upon the complexity of the task at hand. Thus, coaches …

Integrated Analysis Of Untargeted Liver, Serum Metabolome And Gut Microbiome Following Selenium Deficiency Diet In Selenoh Knockout And Wildtype Mice, Richard Eugene Baird

Theses and Dissertations

Selenoprotein H (SELENOH) is an oxidoreductase located in the nucleolus, and its biochemical levels decrease with selenium (Se) deficiency, as reported in mammalian research. This current investigation aimed to understand the impact of nutritional Se deficiency on gut microbial composition and metabolomic profiles. The Firmicutes/Bacteroidota (F/B) ratio, linked to various health conditions, was balanced for wildtype (WT) mice (1.06). In contrast, selenoh knockout (KO) mice associated with dietary Se deprivation had a significantly (p < 0.002) lower ratio (0.56), suggesting dysbiosis. It is believed that SELENOH levels decreased due to the Se deficient diet, and the selenoh KO mice exhibited alterations in microbial community composition and metabolite profiles, as supported by correlative analyses. With respect to the bacterial communities, significant differences between diets occurred for three taxa, including Akkemansia mucinphila, Bacteroides caecimuris, and Parabacteroides goldsteinii. Candida tropicalis, Malassezia restricta, and Cyberlindnera jadinii were three abundant fungal yeasts. Only Cyberlindnera jadinii exhibited significantly greater relative abundance between genotypes and was more abundant in the selenoh KO versus WT mice. Correlation analyses between bacterial and fungal taxa revealed both positive and negative relationships, but no specific trends were observed. The liver and serum metabolomic data contained similar amino acids, lipids, proteins, and carbohydrates. Using NMR spectroscopy, 112 liver metabolites were detected, while GC-TOF-MS analysis of the serum revealed the presence of 172, comprising both polar and nonpolar compounds. The metabolite levels varied significantly when analyzed using multivariate models such as PCA and PLS-DA (VIP scores), particularly for glucose, taurine, lactate, and UDP-glucose, which are associated with energy production and cellular health. Overall, the Se deficient diet had the most significant impact on the microbial community structure and the concentration of key metabolites within liver tissues and serum. Correlation analyses conducted across studies revealed significant linear relationships between metabolites and the microbiome. However, these differences were associated with bacterial and fungal taxa containing low relative abundances. Based on these findings, further investigation into the impact of SELENOH homeostasis on microbial and metabolite profiles should be conducted using selenoh KO mice under various nutritional Se dietary levels.

Characterizing The Impact Of Cover Crop On Soil Microbiome Function Affecting C And N Inputs In Corn Production System, Durga Purushotham Mahesh Chinthalapudi

Theses and Dissertations

Cover cropping (CC) is a widely adopted strategy to improve soil health and microbial diversity in agroecosystems. However, its influence on microbial community dynamics and ecosystem functions remains context-dependent, particularly under variable nitrogen (N) inputs. This dissertation integrates a three-year field study (2021-2024) in corn-based systems with a meta-analysis of 473 soil samples from diverse Mississippi cropping systems to evaluate CC effects on soil microbial structure, function, and ecosystem multifunctionality. In the field study, soil bacterial and fungal communities were profiled using high-throughput amplicon sequencing (16S rRNA for bacteria, ITS2 for fungi). Seven CC treatments ryegrass, balansa, radish, red clover, …

Influence Of Diverse Forage Environments On Honey Bee Colony Health, Angus Catchot Iii

Theses and Dissertations

Honey bees are important pollinators that face a multitude of stressors in their environment such as pathogens, parasite pressure, forage availability and pesticide exposure. This study examined how the makeup of different environments and the stressors related to those environments are affecting honey bee health in Mississippi. A field experiment was conducted during the first year of the study across four distinct landscapes ranging from intensively cultivated cropland to predominantly natural forage habitats to assess the impact of landscape availability on varying honey bee colony health parameters. Locations that had cultivated crops within foraging range produced more honey and brood …

Social Validity Of Functional Analysis Variations, Rita M. Druffner

Theses and Dissertations

The functional analysis was developed to systematically identify the antecedent and consequent conditions mediating challenging behavior. Modifications to the traditional procedures have been developed to address barriers to implementation, including duration, environmental control, and safety. Much of the research surrounding functional analyses addresses effectiveness, barriers to implementation, and practitioner acceptability. However, there is a lack of research assessing caregiver social validity of functional analysis procedures. Social validity is the assessment of the goals, procedures, and outcomes of behavior analytic practice. Even though there has been advocacy for including measures of social within behavior analytic research and practice, there is limited …

Evaluation Of Furrow-Irrigation And Agronomic Management In Mississippi Rice (Oryza Sativa L.), Thomas W. Eubank Iv

Theses and Dissertations

A new non-transgenic rice has been developed called ROXY, which is resistant to formulations of oxyfluorfen. Utilizing the ROXY rice production system in a furrow-irrigated system could help combat troublesome terrestrial weeds and be a viable option for producers. To evaluate the performance of oxyfluorfen in furrow-irrigated ROXY rice production system, two concurrent field studies were conducted at the Delta Research and Extension Center in Stoneville, MS, from 2022 to 2024. The first study evaluated residual grass and broadleaf weed control with oxyfluorfen applied delayed-preemergence (DPRE). Factor A was oxyfluorfen rates of 0, 700, and 981 g ai ha-1. Factor …

Strategic Use Of Exogenous Feed Enzymes And Sodium Bisulfate To Optimize Broiler Production, Spencer Thomas Karn

Theses and Dissertations

Poultry producers must continually evaluate nutritional strategies to enhance broiler performance and sustainability. Chapter II assessed sodium bisulfate (SB) applied to litter, feed, and water across a 42-day grow-out. Applying SB to litter reduced pH, while 0.3% and 0.4% dietary SB improved feed conversion ratio (FCR). Water acidification with SB during the final week did not impair performance, supporting its use as a preharvest intervention. Chapter III evaluated phytase at 500, 1500, and 2000 FTU/kg, with or without protease, in reduced amino acid diets over 56 days. Birds fed a nutrient-adequate diet with 1500 FTU/kg phytase outperformed all reduced-amino acid …

Understanding Pollinator-Forb Interactions And Evaluating Trapping Methods For Pollinator Monitoring In Lawns Of The Southeastern United States, Sara Rose Kirby

Theses and Dissertations

Urban turfgrass landscapes are widespread across the southeastern United States but offer limited ecological value under conventional management. This thesis evaluates the pollinator support potential of ten forb species commonly found in low-maintenance lawns and assesses the effectiveness of two insect sampling methods, sweep netting and pan trapping. Over two years of field surveys, native forbs such as Symphyotrichum divaricatum and Claytonia virginica supported significantly greater insect abundance and diversity than introduced species. Network and modularity analyses revealed that native plants facilitated more specialized pollinator interactions, including those involving oligolectic bee species. In a complementary study, pan traps effectively sampled …

Finite Element Modeling Of Plasma Membrane Injury From Mechanical Stress: A Combined Finite Element And Machine Learning Approach, Eric Flynn Mabowitz

Theses and Dissertations

Low back pain is a leading cause of disability across a wide range of occupations and environments. Exposure to whole-body vibration (WBV) has been linked to an increased prevalence of low back pain, as well as certain neurophysiological complications. While current understanding of WBV effects is largely based on tissue- and whole-body-level studies, a significant gap remains in knowledge regarding how vibrational forces propagate through individual cells. This knowledge gap limits a comprehensive understanding of how these forces affect the human body at the microscopic level. To address this, the present study employs both two-dimensional (2D) and three-dimensional (3D) finite …

My Grandparents Raised Me: The Role Of Formative Individual And Family Experiences In Predicting Emerging Adult Substance Use, Attachment, And Mental Health Outcomes, Acacia Lopez

Theses and Dissertations

Individuals raised in a grandfamily, or family structure in which a grandparent raises their grandchildren, experience higher rates of adverse childhood experiences (ACEs), insecure attachment, and negative mental health outcomes during childhood. Literature on outcomes of these individuals across the lifespan is extremely limited, however, and it is unclear how formative individual and family experiences of being raised by grandparents carry into emerging adulthood (e.g., 18 to 25-years-old). Emerging adulthood is a developmental stage marked by significant instability and unpredictability that is linked with increased vulnerability to mental health concerns and substance use. It has been identified as an important …

Impact Of Buffered Dry Vinegar And Fermented Onion Juice On The Quality And Shelf-Life Of Fresh Pork Breakfast Sausage, Emily M. Little

Theses and Dissertations

The demand for clean-label meat products has increased interest in natural alternatives to synthetic antioxidants and antimicrobials. This study evaluated the effects of buffered dry vinegar (BDV), fermented onion juice (FOJ), and their combination (CMB) on microbial stability and sensory quality of pork sausage during 9 days of refrigerated storage. Sausages were assigned to control, FOJ (0.5%), BDV (0.5%), or CMB (0.25% each) treatments. BDV and CMB significantly reduced aerobic and psychrotrophic counts by days 7-9, while yeast increased across all treatments over time, reaching ~7 Log CFU/g by day 9. Sensory analysis revealed lower oxidation and off-note intensity in …