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Sga 57 Senate 2025-10-03 Minutes, Niu Student Government Association Senate Oct 2025

Sga 57 Senate 2025-10-03 Minutes, Niu Student Government Association Senate

Student Government Association Archives

No abstract provided.


Covid-19 Resilience In Indigenous Communities: A Community Capitals Approach, Kristin A. Drexler, Michelle Watts, Casey Skvorc, Bridget Kimsey Oct 2025

Covid-19 Resilience In Indigenous Communities: A Community Capitals Approach, Kristin A. Drexler, Michelle Watts, Casey Skvorc, Bridget Kimsey

Journal of Indigenous Research

The COVID-19 pandemic has had a profound impact on rural American Indian/Alaska Native communities. During our multi-year study, in-depth interview data was collected in Indigenous communities from over 160 Tribal leaders and members in Alaska, New Mexico, Belize and Guatemala. In interviews, participants shared their lived experience during the pandemic, both negative impacts and factors of resilience. This article focuses on the methodology and theoretical framework of Community Capitals Framework (CCF). Using CCF, interview data was coded and analyzed using a modified CCF model. Our study aims to better understand how Indigenous communities and leaders drew on human and socio-cultural …


Spiritual Grounding In Sacred Soil: The Picuris/Peñasco Valley As A Model For Catholic Unity Across Cultures, Gabriel Antonio Gonzales Oct 2025

Spiritual Grounding In Sacred Soil: The Picuris/Peñasco Valley As A Model For Catholic Unity Across Cultures, Gabriel Antonio Gonzales

Master of Theological Studies Honors Theses

This thesis examines the Picuris/Peñasco Valley of Northern New Mexico as a unique case study for understanding Catholic unity amidst cultural plurality and historical tension. The study investigates how the confluence of Picuris Pueblo (Tiwa) Indigenous spirituality and Hispano/Spanish Colonial Catholic traditions has forged a profoundly localized and resilient faith community. Drawing upon historical analysis of colonial resistance, cultural anthropology, and theological reflection, this work argues that the concept of sacred land (sacred soil) functions as the central unifying principle. It reveals how the shared commitment to the land facilitated a process of religious and cultural syncretism, creating a form …


The Indiana Statesman, October 2, 2025, Indiana State University Oct 2025

The Indiana Statesman, October 2, 2025, Indiana State University

Student Newspaper

20th annual Bat Festival; Student Market coming to the fountain


Oncopacket: Integration Of Cancer Research Data Using Ga4gh Phenopackets., Michael Sierk, Daniel Danis, Sujay Patil, Nobal Kishor, Rajdeep Mondal, Abhishek Jha, Qingrong Chen, Chunhua Yan, Monica Munoz-Torres, Daoud Meerzaman, Peter N Robinson, Justin T Reese Oct 2025

Oncopacket: Integration Of Cancer Research Data Using Ga4gh Phenopackets., Michael Sierk, Daniel Danis, Sujay Patil, Nobal Kishor, Rajdeep Mondal, Abhishek Jha, Qingrong Chen, Chunhua Yan, Monica Munoz-Torres, Daoud Meerzaman, Peter N Robinson, Justin T Reese

Faculty Research 2025

SUMMARY: Lack of data integration remains a significant impediment to cancer research, and many analyses still require customized software to transform and prepare cancer data. We describe a software package to harmonize genetic and clinical cancer data into the GA4GH Phenopacket schema, an ISO standard for representing clinical case data. We integrated demographic, mutation, morphology, diagnosis, intervention, and survival data using case data from the National Cancer Institute for 12 cancer types. The Phenopacket standard provides a foundation for downstream use, including sophisticated statistical and AI/ML analyses. We demonstrate fitness for purpose by using the integrated data to recapitulate a …


Automating Candidate Gene Prioritization With Large Language Models: From Naive Scoring To Literature-Grounded Validation., Taushif Khan, Mohammed Toufiq, Marina Yurieva, Nitaya Indrawattana, Akanitt Jittmittraphap, Nathamon Kosoltanapiwat, Pornpan Pumirat, Passanesh Sukphopetch, Muthita Vanaporn, Karolina Palucka, Basirudeen Syed Ahamed Kabeer, Darawan Rinchai, Damien Chaussabel Oct 2025

Automating Candidate Gene Prioritization With Large Language Models: From Naive Scoring To Literature-Grounded Validation., Taushif Khan, Mohammed Toufiq, Marina Yurieva, Nitaya Indrawattana, Akanitt Jittmittraphap, Nathamon Kosoltanapiwat, Pornpan Pumirat, Passanesh Sukphopetch, Muthita Vanaporn, Karolina Palucka, Basirudeen Syed Ahamed Kabeer, Darawan Rinchai, Damien Chaussabel

Faculty Research 2025

MOTIVATION: Identifying promising therapeutic targets from thousands of genes in transcriptomic studies remains a major bottleneck in biomedical research. While large language models (LLMs) show potential for gene prioritization, they suffer from hallucination and lack systematic validation against expert knowledge.

RESULTS: The framework identified 609 sepsis-relevant genes with >94% filtering efficiency, demonstrating strong enrichment for inflammatory pathways including TNF-α signaling, complement activation, and interferon responses. Literature validation yielded 30 ultra-high confidence therapeutic candidates, including both established sepsis genes (IL10, TREM1, S100A9, NLRP3) and novel targets warranting investigation. Benchmark validation against expert-curated databases achieved 71.2% recall, with systematic correlation between computational …


October 2, 2025, Caa Oct 2025

October 2, 2025, Caa

Minutes

No abstract provided.


Growth Mindset In The Mathematics Classroom: Studying The Effects Of A Growth Mindset Intervention On High School Students In A Geometry Classroom, Katelyn Strauss Oct 2025

Growth Mindset In The Mathematics Classroom: Studying The Effects Of A Growth Mindset Intervention On High School Students In A Geometry Classroom, Katelyn Strauss

Mathematics Graduate Theses

Having a growth mindset is crucial to being successful in a mathematics classroom. However, many students believe themselves to be either “mathematics people” or “not mathematics people”. When students believe they are not a mathematics person, they are far less likely to engage in material where they face struggles, and thus they miss out on valuable learning. A review of the literature has show that students have been able to shift their mindset from fixed to growth through a series of interventions. I used a unit in Geometry to see how a growth mindset intervention would affect the mindset of …


The Current - Volume 36 Issue 3, Nova Southeastern University Oct 2025

The Current - Volume 36 Issue 3, Nova Southeastern University

Student Newspapers

No abstract provided.


Editorial: Decoding Vascular Aging: Unraveling The Enigma Of Pathological Conditions And Pre-Mature Vascular Aging, Mitra Esfandiarei, Roshanak Rahimian Oct 2025

Editorial: Decoding Vascular Aging: Unraveling The Enigma Of Pathological Conditions And Pre-Mature Vascular Aging, Mitra Esfandiarei, Roshanak Rahimian

Pacific Faculty Work

No abstract provided.


The Colby Echo (2025-10-02), Colby College Oct 2025

The Colby Echo (2025-10-02), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly during the academic year, 1898-present.


Functional Effects Of Heavy Metal Exposures On N6-Methyladenosine (M6a) Methylation And Other Epitranscriptomic Modifications In The Central Nervous System, Niraj Lodhi, Lauren Powell, Jay S. Schneider Oct 2025

Functional Effects Of Heavy Metal Exposures On N6-Methyladenosine (M6a) Methylation And Other Epitranscriptomic Modifications In The Central Nervous System, Niraj Lodhi, Lauren Powell, Jay S. Schneider

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Among different RNA methylations, N6-methyladenosine (m6A) is the most abundant in the brain and determines the fate of RNA through reversible processes using methyltransferases, demethylases, and methyl-binding proteins. The reversibility of m6A is an emerging regulatory mechanism for gene expression, regulating many aspects of RNA metabolism and influencing learning and memory processes. Global m6A profiles are dynamically modified via the activity of various writers, readers, and erasers. However, m6A alterations from exposure to heavy metals, including the metals lead (Pb), cadmium (Cd), cobalt (Co), and manganese (Mn) and the metalloid arsenic (As), and the impact on brain function, are not …


A Needed Nomenclature For Nucleosomes, Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Sung Hee Baek, Mark T Bedford, Emily Bernstein, Jacques Côté, Yael David, John M Denu, Beat Fierz, Benjamin A Garcia, Karen C Glass, Or Gozani, Kristian Helin, Steven Henikoff, Ole N Jensen, Steven Z Josefowicz, Neil L Kelleher, Tatiana G Kutateladze, Herbert H Lindner, Chao Lu, Karolin Luger, Parag Mallick, Catherine A Musselman, Tom W Muir, Ljiljana Paša-Tolić, Robert Schneider, Xiaobing Shi, Yang Shi, Simone Sidoli, Lloyd M Smith, Jessica K Tyler, Cynthia Wolberger, Jerry L Workman, Brian D Strahl, Nicolas L Young Oct 2025

A Needed Nomenclature For Nucleosomes, Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Sung Hee Baek, Mark T Bedford, Emily Bernstein, Jacques Côté, Yael David, John M Denu, Beat Fierz, Benjamin A Garcia, Karen C Glass, Or Gozani, Kristian Helin, Steven Henikoff, Ole N Jensen, Steven Z Josefowicz, Neil L Kelleher, Tatiana G Kutateladze, Herbert H Lindner, Chao Lu, Karolin Luger, Parag Mallick, Catherine A Musselman, Tom W Muir, Ljiljana Paša-Tolić, Robert Schneider, Xiaobing Shi, Yang Shi, Simone Sidoli, Lloyd M Smith, Jessica K Tyler, Cynthia Wolberger, Jerry L Workman, Brian D Strahl, Nicolas L Young

Faculty, Staff and Student Publications

Histone post-translational modifications (PTMs) are crucial to eukaryotic genome regulation, with a range of reported functions and mechanisms of action. Though often studied individually, it has long been recognized that the modifications function by combinatorial synergy or antagonism. Interplay may involve PTMs on the same histone, within the same nucleosome (containing a histone octamer), or between nucleosomes in higher-order chromatin. Given this, the field must distinguish ever greater complexity, and the context in which it is studied, with brevity and precision. The proteoform was introduced to define individual forms of a protein by sequence and PTMs, followed by the nucleoform …


Genome-Wide Analysis Of Dna Methylation Signatures Linking Prenatal Exposure To The Chinese Great Famine And Blood Lipids In Late Adulthood: The Genomic Research Of The Chinese Famine (Grecf) Study, Huan Wang, Luqi Shen, Tingting Liu, Ruiyuan Zhang, Zhenghe Wang, Jingkai Wei, Ye Shen, Jinzhen Guo, Toni Miles, Changwei Li, Zhiyong Zou Oct 2025

Genome-Wide Analysis Of Dna Methylation Signatures Linking Prenatal Exposure To The Chinese Great Famine And Blood Lipids In Late Adulthood: The Genomic Research Of The Chinese Famine (Grecf) Study, Huan Wang, Luqi Shen, Tingting Liu, Ruiyuan Zhang, Zhenghe Wang, Jingkai Wei, Ye Shen, Jinzhen Guo, Toni Miles, Changwei Li, Zhiyong Zou

Faculty, Staff and Student Publications

Background/objectives: Prenatal exposure to famine can lead to lasting health effects through changes in DNA methylation. This study aims to evaluate the impact of prenatal exposure to the Chinses Great Famine (1959-1961) on human epigenome and the subsequent influence on blood lipids.

Methods: We conducted an epigenome-wide association study (EWAS) of peripheral blood-based DNA methylation and prenatal exposure to the Chinese Great Famine as well as blood lipids among eight participants exposed to famine and eight sex-matched participants (born ≤ 3 years after the famine). Genome-wide DNA methylation sites were profiled using the Illumina EPIC BeadChip, which covers 850K methylation …


October 2, 2025, The Daily Mississippian Oct 2025

October 2, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Quaker Campus, October 2, 2025 (Vol. 24, Issue 3), Whittier College Oct 2025

Quaker Campus, October 2, 2025 (Vol. 24, Issue 3), Whittier College

Quaker Campus

No abstract provided.


Spatially Variable Response Of Antarctica's Ice Sheets To Orbital Forcing During The Pliocene, Molly P. Patterson, Christiana Rosenberg, Masanobu Yamamoto, Oscar Romero, Mei Nelissen, Francesca Sangiorigi, Nick Golledge, Georgia Grant, William Arnuk, Benjamin Keisling, Tim Naish, Richard Levy, Stephen Meyers, Nicholas Sullivan, Jeanine Ash, Denise Kulhanek, Brian Romans, Natalia Verela, Harold Jones, Francois Beny, Imogene Browne, Giuseppe Cortese, Isabela Cordeiro De Sousa, Justin Dodd, Oliver Esper, Jenny Gales, David Harwood, Saki Ishino, Sookwan Kim, Sunghan Kim Oct 2025

Spatially Variable Response Of Antarctica's Ice Sheets To Orbital Forcing During The Pliocene, Molly P. Patterson, Christiana Rosenberg, Masanobu Yamamoto, Oscar Romero, Mei Nelissen, Francesca Sangiorigi, Nick Golledge, Georgia Grant, William Arnuk, Benjamin Keisling, Tim Naish, Richard Levy, Stephen Meyers, Nicholas Sullivan, Jeanine Ash, Denise Kulhanek, Brian Romans, Natalia Verela, Harold Jones, Francois Beny, Imogene Browne, Giuseppe Cortese, Isabela Cordeiro De Sousa, Justin Dodd, Oliver Esper, Jenny Gales, David Harwood, Saki Ishino, Sookwan Kim, Sunghan Kim

School of Biological and Marine Sciences

Variations in Earth’s orbit pace global ice-volume/sea-level changes, but the variability in the response for different sectors of the Antarctic Ice Sheet (AIS) to orbitally-forced climate change remains unclear. We present geological records of iceberg-rafted debris (IBRD) and other proxies from locations adjacent to the West Antarctic Ice Sheet (WAIS) and East Antarctic Ice Sheet (EAIS) spanning ~3.3-2.3 Ma. Iceberg calving events from the WAIS recorded in Ross Sea sediment cores show a linear response to orbital forcing at timescales corresponding to obliquity (40 kyr) and precession (23-19 kyr) modulated by eccentricity (100 kyr). This contrasts with records adjacent to …


Disabilities Project Initial Report, Enaya Othman Oct 2025

Disabilities Project Initial Report, Enaya Othman

Journal of Gender, Ethnic, and Cross-Cultural Studies

This report describes the processes, aims, and outcomes of the Disabilities Digital Archive, a project conducted as part of Arab and Muslim Women’s Research and Resource Institute’s vision to create data and oral histories regarding women’s experiences and transform them into meaningful information. To this end, this project seeks to explore gendered disability and facilitate more complex understandings of disability at the intersection of gender, culture, immigration, and other modes of identity. By collecting data from Muslim community members in Milwaukee, including people with differences of ability and their families, caregivers, Imams and religious scholars, community organization leaders, and health …


Gendered Disabilities Project Report, Enaya Othman Oct 2025

Gendered Disabilities Project Report, Enaya Othman

Journal of Gender, Ethnic, and Cross-Cultural Studies

This report presents our yearly progress in the third year of the Gendered Disabilities Project that aims to collect data and create a digital database on the experiences of Muslim women as people with disability or caretakers, including their access to healthcare services. With the outbreak of the COVID-19 pandemic, which has influenced the structure of our research and has strong implications for our research topic, we have integrated the issue into our themes. Meanwhile, we adapted our methodology to the measures and thus conducted the interviews virtually. The remainder of this report first focuses on the integration of COVID19 …


Educating Future Nurse Practitioners And Physician Associates On Pretreatment Of Swallowing In Head And Neck Cancer, Hannah M. Berk, Erin L. O'Bryan, Imran Musaji, Carly A. Thomas, Jamie Harrington Oct 2025

Educating Future Nurse Practitioners And Physician Associates On Pretreatment Of Swallowing In Head And Neck Cancer, Hannah M. Berk, Erin L. O'Bryan, Imran Musaji, Carly A. Thomas, Jamie Harrington

Teaching and Learning in Communication Sciences & Disorders

Head and neck cancer treatment frequently results in long-term severe swallowing deficits, often requiring feeding tube dependency. Patients who have completed swallowing exercise programs before and during cancer treatment experienced more positive swallowing outcomes, but most patients are not referred for swallowing intervention early enough in their care to prevent long-term deficits. This student research project aimed to measure health profession students’ knowledge of swallowing pretreatment for head and neck cancer patients and to investigate the impact of an educational module developed and presented by a Communication Sciences and Disorders graduate student to improve knowledge and awareness of this clinical …


Blood Lines, Sherry Coman Oct 2025

Blood Lines, Sherry Coman

Journal of Religion & Film

This is a film review of Blood Lines (2025), directed by Gail Maurice.


Lived Islam In Films: Faith-Based Resilient Responses Of Syrian Refugees, Jumana S. Al-Ahmad Oct 2025

Lived Islam In Films: Faith-Based Resilient Responses Of Syrian Refugees, Jumana S. Al-Ahmad

Journal of Religion & Film

This article provides educators in fields such as Middle Eastern studies, refugee studies, cultural and Islamic studies with a framework from documentaries to challenge stereotypes about Muslim refugees and migrants. Using the framework of lived Islam, the article explores how Syrian Muslim migrants, as seen in documentaries, draw on their faith to build resilience that enables them to continue striving for better lives. Resilience is defined as the ability to overcome challenges and catastrophes, envision solutions, and lead a purposeful life. This article conceptualizes resilience not only as a personal trait but also as a collective tool for survival and …


Monstrous Girls And Celestial Lovers: Fantasy, Fear, And Female Adolescence In The Malayalam Films Ennu Swantham Janakikutty And Njan Gandharvan, Helena Reddington Oct 2025

Monstrous Girls And Celestial Lovers: Fantasy, Fear, And Female Adolescence In The Malayalam Films Ennu Swantham Janakikutty And Njan Gandharvan, Helena Reddington

Journal of Religion & Film

The Malayalam films Ennu Swantham Janakikutty and Njan Gandharvan reimagine figures from Kerala folklore, namely the Yakṣi and the Gandharva, within coming-of-age narratives. Both films position the characters of the Yakṣi and the Gandharva as fantastical figures who usher the young female protagonist into maturity. Rather than offering a pan-Hindu survey, this study focuses specifically on Kerala’s unique reimaginings of these celestial beings, where these figures carry distinct cultural meanings. This interpretive analysis is situated at the intersection of film studies, religious studies, as well as gender and sexuality studies, drawing particularly on feminist theory and critical approaches to vernacular …


Folinic Acid For Impaired Folate Metabolism To Improve Communication Deficits In Children With Autism Spectrum Disorder, Cheri L. Collins Oct 2025

Folinic Acid For Impaired Folate Metabolism To Improve Communication Deficits In Children With Autism Spectrum Disorder, Cheri L. Collins

Lynchburg Journal of Medical Science

The purpose of this review is to evaluate the efficacy of folinic acid supplementation in addressing communication deficits in children with autism spectrum disorder (ASD). ASD is characterized by persistent deficiency in social communication and interaction, accompanied by restricted and repetitive patterns of behavior. Communication impairments are a core challenge in ASD and remain difficult to treat. Although there is no confirmed etiology, emerging evidence suggests that a subset of children with ASD may have underlying abnormalities in folate metabolism. Folate receptor alpha autoantibodies (FRAAs) are immunoglobulins that interfere with folate metabolism. When present, they can disrupt the transfer of …


Problematic Smartphone Use Experiences Of Students, Gbolahan Olasina Oct 2025

Problematic Smartphone Use Experiences Of Students, Gbolahan Olasina

The African Journal of Information Systems

Smartphones extend people's opportunities by improving their daily living and well-being. Hence, given the tool’s features and affordances that promote human development, smartphones facilitate the achievement of the individual liberties and freedoms of ordinary people. However, there are serious concerns about the emotional, social and cultural factors underlying smartphone usage patterns and their association with problematic use and depressive behaviors. Therefore, the overriding goal of the research reported on in this paper was to investigate how smartphone use influences individuals’ emotional wellness, interpersonal relationships and sociocultural contexts. Existing academic literature indicated that there was a need to investigate the intricate …


Biocompatibility And Anti-Inflammatory Effects Of Thai Cannabidiol-Containing Topical Anesthetic Gel Prototype In A Dermal Irritation Test, Pasutha Thunyakitpisal, Supattarayan Thongjit, Apitchaya Pruksametanan, Wijit Banlunara Assoc. Prof. Oct 2025

Biocompatibility And Anti-Inflammatory Effects Of Thai Cannabidiol-Containing Topical Anesthetic Gel Prototype In A Dermal Irritation Test, Pasutha Thunyakitpisal, Supattarayan Thongjit, Apitchaya Pruksametanan, Wijit Banlunara Assoc. Prof.

The Thai Journal of Veterinary Medicine

The objective of this study is to investigate and compare the effect of cannabidiol (CBD)-containing and non-CBD topical anesthetic gel prototypes on skin irritation in rabbits at 24, 48, and 72 h post-application. Topical anesthetic gel prototypes containing 0.1% CBD and without CBD were developed. Six rabbits (Oryctolagus cuniculus) were used for skin irritation testing according to ISO 10993-23: 2021. The animals were randomly and equally divided into two groups (CBD and non-CBD gel groups). The gels were applied to the animals’ skin at the dorsal area of the flank with good contact for 4 h. Distilled water …


Exploring The Experience Of Nursing Students During Their Community Health Nursing Clinical Placement At Schools, Lina Ghosn Nouwayhed Oct 2025

Exploring The Experience Of Nursing Students During Their Community Health Nursing Clinical Placement At Schools, Lina Ghosn Nouwayhed

Dissertations

Community health nursing is an exciting, challenging, and evolving field that creatively integrates various areas of nursing practice with public health knowledge (Stanhope & Lancaster, 2016). Learning in practical settings is invaluable for student nurses; that is why clinical placements account for 50% of nursing curriculum requirements (Henderson, 2011). At Makassed University of Beirut, the community nursing practicum takes place in schools, with school nurses serving as mentors during these placements.

This research study aims to:

  • Explore the experiences of student nurses during community clinical practice.
  • Develop guidelines to enhance learning during community clinical practice.

The study sample consisted of …


The Model Of The Formation Of Adolescent Sexual Orientation In Indonesia: Case-Control Study, Putri Azzahroh, Arni Amir, Adang Bachtiar, Firdawati Firdawati Oct 2025

The Model Of The Formation Of Adolescent Sexual Orientation In Indonesia: Case-Control Study, Putri Azzahroh, Arni Amir, Adang Bachtiar, Firdawati Firdawati

Journal of Health Research

Background: This study examines the social construction of sexual orientation among adolescents, particularly non-heterosexual, in Daerah Khusus Ibukota (DKI) Jakarta, Indonesia. Currently, non-heterosexual adolescents tend to recognize their sexual attraction earlier than previous generations.

Methods: A mixed methods approach was used. We conducted in-depth interviews with foundations focused on HIV/AIDS management and groups with non-heterosexual orientations. For the quantitative portion, 267 adolescents (89 non-heterosexual and 178 heterosexual) completed a validated questionnaire. We conducted univariate and bivariate analyses examining gender distribution as well as the association between social construction factors and the formation of sexual orientation.

Results: Logistic regression identified key …


High Occurrence Of Long Bone Nonunion : Assessing Significant Biological Risk Factors And Management Results, Bimo Sasono, Aldy Dion Oct 2025

High Occurrence Of Long Bone Nonunion : Assessing Significant Biological Risk Factors And Management Results, Bimo Sasono, Aldy Dion

Journal of Health Research

Background: A comprehensive study evaluated the risk of nonunion per fracture in a population of over four million adults and determined that rates vary depending on patients' risk factors, nonunion rates can reach in excess of 10%. This study aims to address the issue by scrutinizing the demographic characteristics of patients, pinpointing the biological risk factors for long bone nonunion and evaluating the nonunion management effectiveness.

Methods: This analytical, observational retrospective cohort study used medical record data from a regional hospital in Surabaya, Indonesia (2020–2023), involving 147 eligible patients. Data were analyzed using logistic regression with a significance level of …


Methylation Of The Dat1 Dopamine Transporter Gene In Combat Sport Athletes: Associations With Impulsivity And Reward Sensitivity, Milena Lachowicz, Remigiusz Recław, Aleksandra Suchanecka, Krzysztof Chmielowiec, Elżbieta Grzywacz, Jolanta Chmielowiec, Kinga Łosińska, Anna Grzywacz Oct 2025

Methylation Of The Dat1 Dopamine Transporter Gene In Combat Sport Athletes: Associations With Impulsivity And Reward Sensitivity, Milena Lachowicz, Remigiusz Recław, Aleksandra Suchanecka, Krzysztof Chmielowiec, Elżbieta Grzywacz, Jolanta Chmielowiec, Kinga Łosińska, Anna Grzywacz

Baltic Journal of Health and Physical Activity

Epigenetic mechanisms, such as DNA methylation, modulate behavioral traits, including impulsivity and reward sensitivity. The dopamine transporter gene (DAT1) plays a key role in dopaminergic function and is associated with self-regulation, attention, and the trait of addiction. This study summarized the DAT1 methylation status in patients practicing combat sports and its association with impulsivity, ADHD symptoms, and consequence sensitivity. One hundred control subjects were recruited using the Barratt Impulsivity Scale (BIS), the ADHD scale, and the Opportunity Response Scale. DAT1 methylation was measured using the bisulfite ionization method. A correlation analysis was performed with the comparison group. Athletes …