Digital Commons Network^™

The Potential Effect Of Ginger As An Adjuvant Treatment In Mice With Induced Multiple Sclerosis: Histological And Physiological Studies, Abdulkader M. A. Shaikh Omar, Salim M. El-Hamidy, Dalia Mohammed Kenani, Safa Hassan Qahl, Ghadah Alshahrani

The Journal of King Abdulaziz University: Science

Objectives: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system that affect liver and kidneys. Newer treatments for MS were developed such as drug Ibudilast (IBD) and natural plants such as 6-Shogaols (Ginger components). The current study investigates the protective effects of IBD, 6-Shogaols, and their combination on the liver and kidneys of MS mice model.

Methods: Thirty-five mice were used. The study duration was 9 weeks; 5 weeks for demyelination induction by Cuprizone (CPZ) followed by 4 weeks for remyelination. At demyelination, mice were assigned into; Control group (n = 10) and CPZ group (n = …

Reducing Delirium In Older Adults: The Role Of Quiet Hours During Hospitalization, Kelly Hermawan Bsn, Rn

Nurse Residency

In older adults how does the implementation of quiet hours compared to no quiet hours affect the incidence of delirium as measured by positive cam score during hospitalization?

The Honors Oracle, November 2025, Honors College

Honors Oracle

Marshall University’s Honors College newsletter.

Beyond Phonics: Neuroaesthetic And Symbolic Divergence In Culturally Responsive Dyslexia Screening, Piper Hutson, James Hutson

Faculty Scholarship

Recent advances in neuroscience and educational technology have challenged the traditional phonological-deficit model of dyslexia, revealing the profound influence of visual-symbolic processing, neuroaesthetic resonance, and cultural context in the reading brain. This article interrogates prevailing assessment paradigms by synthesizing research on the Visual Word Form Area (VWFA), cross-linguistic literacy systems, and emerging neurodiversity frameworks. The study addresses the urgent need to reconceptualize dyslexia as a heterogeneous divergence in symbolic processing—rooted as much in neuroaesthetic and visuospatial alignment as in phonemic awareness. Existing screeners, predominantly optimized for English and other Latin-based scripts, systematically neglect the cognitive realities of learners in multilingual …

Flea News 96 (November 2025), R. L. Bossard

Flea News

Flea News is a twice-yearly newsletter about fleas (Siphonaptera). Before including in publications any of the citations given here, please review for accuracy and correct formatting. Many of our sources are abstracting journals and current literature sources, and editors have not necessarily checked citations.

Announcements

Obituary: Lane Douglas Foil (June 16, 1949 - June 22, 2025)

Siphonaptera Literature (2025): Taxonomy, Conservation, Hosts and Distributions, Physiology and Morphology, Evolution, Ecology, Pathology and Control, Microbial Symbionts

Resonant Body Communication For Neurodivergent Contexts: A Multimodal, Temporally Elastic Blueprint For Inclusive Biometric Systems, Piper Hutson, James Hutson

Faculty Scholarship

Prevailing emotion-sensing systems privilege a facial-and-gaze paradigm that encodes neurotypical tempo, channel priority, and expression classes, thereby mischaracterizing or erasing neurodivergent communication. This article advances a design-oriented framework for biometric sensing that centers resonant body communication: temporally extended, multimodal, and environmentally situated patterns of posture, gesture, rhythm, and interoception that carry affective meaning. Through an integrative methodology that synthesizes cognitive neuroscience, embodied arts practices, and human–computer interaction, the study formalizes a theoretical model with four pillars: temporal elasticity, multimodal sensory hierarchies, resonant gestures and rhythmic entrainment, and environmental attunement. Building on this model, the article specifies technical requirements for next-generation …

Fisheries Research Report No. 360: Best Practice And Policy In Australian Abalone Stock Enhancement, Frdc Project No. 2019/110, Lachlan W. Strain, Anthony M. Hart

Fisheries Research Reports

This report provides the most comprehensive evaluation of abalone stock enhancement in Australia to date. The review demonstrates the significant advancements in abalone stock enhancement and concludes that the knowledge and expertise to undertake large-scale (commercial) abalone stock enhancement is present within Australia. The development of policy/guidelines on marine stock enhancement has occurred across all jurisdictions but is still limited in abalone specific policy that could facilitate commercial enhancement programs effectively. Unfortunately, there is a high degree of variability between jurisdictions in both capacity and policy, which was reflected in the jurisdictional scoring against current “best practice” on marine stock …

Identifying Superior Finger Millet (Eleusine Coracana L.) Landraces Using The Multi-Trait Genotype-Ideotype Distance Index (Mgidi), Sujan Chapagaina, Bishnu Prasad Kandela, Sudikshya Shresthaa, Ankur Poudela, Shubh Pravat Singh Yadavb

Extension Publications

Genetic variability and selection are crucial for finger millet breeding programs to maximize genetic gain and productivity. This study evaluated 18 finger millet landraces cultivated in the mid-hills of Nepal, along with ‘Kavre Kodo 2’ as a check variety, assessing 14 agro-morphological traits. The objective was to identify superior finger millet landraces using a multivariate approach based on the multi-trait genotype– ideotype distance index (MGIDI). The experiment was conducted in a randomized complete block design (RCBD) with three replications. Principal component analysis revealed that the first five components collectively accounted for 80.8% of the total variation, reflecting the genetic relatedness …

Characterization Of Colorectal Cancer Cell Responses Using A Wound-Healing Scratch Assay Model On Wild-Type (P53 +/+) And Knockout (P53 -/-), Mehrael Faragalla, Karen Barsoum, Erick Spears

Science University Research Symposium (SURS)

Colorectal cancer progression is driven in part by dysregulated signaling pathways that alter cell growth and migration. One key pathway is the Wnt signaling pathway, a key regulator in colorectal tumorigenesis, which promotes MYC overexpression, leading to uncontrolled proliferation. Interestingly, in the absence of p53, MYC has been found to induce expression of the tumor suppressor gene EGR1, shifting the cellular response toward apoptosis rather than growth. This study investigates the MYC–EGR1 pathway in HCT116 colorectal cancer cells with either wild-type (p53+/+) or knockout of the TP53 gene (p53−/−). Early findings indicate that p53+/+ cells exhibit faster initial growth compared …

Impact Of Height On Primrose Leaf Litter Decomposition, Lilianna Wrenne, Jacey Cardenas, Danner Brown, Wyatt Fooks, Darlene Panvini

Science University Research Symposium (SURS)

Decomposition is a crucial process in nutrient cycling, where dead organic matter turns into nutrients for the environment. Height is a significant abiotic factor that can influence these factors. Dried primrose was chosen for this experiment to test how much height affects decomposition; 8 mesh bags were filled with 4.0g of dried primrose leaves. Four bags were placed at ground level, and four were placed on top of a plant, 2ft above the ground. Using the fishing line, the bags at each site were tied together to prevent them from blowing away. By changing the height of the plants, the …

Comparative Decomposition Rates Of Prickly Pear And Sage Using Litterbags, Curtis Jang, Vy Ly, Ashlyn Reagan, Ellie Sebaugh, Darlene Panvini

Science University Research Symposium (SURS)

Litterbags are used to study nutrient cycling and track the rate of decomposition over time. Decomposition rates may vary between plant species due to various factors. One factor includes the abundance of lignin, or a structural component that provides support to a plant, which can slow the rate of decomposition. This study compared the decomposition rate of sage (Salvia officinalis), which has higher lignin levels, and prickly pear (Opuntia humifusa), which has higher water content and thus lower lignin levels. Four samples of each species, with two replicates each, were initially weighed and then placed in …

Presence Of Ophiognomonia Clavivignenti-Juglandacearum On Juglans Cinerea At Beaman Park In Nashville, Tennessee, Corinne Parker, Kidist Aklile, Darlene Panvini

Science University Research Symposium (SURS)

Butternut trees, (white walnut, Juglans cinerea), are infected by a fatal canker, Ophiognomonia clavigignenti-juglandacearum (O-cj), which impacts the survival and population density of the species. Once found throughout the eastern United States, the species has decreased considerably. Due to its uncommon occurrence in Middle Tennessee, the conditions of J. cinerea were investigated at Beaman Park in Nashville, TN. All butternut trees were hypothesized to be infected by O-cj. Each known tree in the park was examined to assess its bark health and determine the presence of the canker. Ecosystem analyses around each tree included surveys of soil characteristics, …

Capacity Maximization Through Production Lead Time Reduction Of Company Xyz With The Use Of Dmaic Methodology, Aaron Will G. Delmo, Julius Angelo D.J. Galang, Maria Liezel C. Eusebio

Journal Article

Company XYZ, an industrial printing company, has been declining in capacity and actual output resulting in monthly unrealized revenue. The goal of this study is to maximize the current capacity, decreasing production lead time by at least 12%, with the use of Define, Measure, Analyze, Improve and Control methodology. The focus was set on the offset machine and packaging process which are the most crucial steps based on Pareto Analysis. Fishbone diagram was then utilized to identify the root cause of the problems with the aforementioned processes. These root causes are further assessed using the CNX analysis. The main root …

Gut Bacterial Dysbiosis In Pediatric Severe Malaria Associates With Post-Discharge Mortality, Olivia Bednarski, Sawyer Lehman, David Mzinza, Caroline Kazinga, Ruth Namazzi, Robert Opoka, Jie Ren, Tuan Tran, Terrie Taylor, Karl Seydel

Paediatrics and Child Health, East Africa

Gut microbiota have been implicated in severe malaria in murine models, but their contribution to the pathogenesis of severe malaria in children is unknown. Here we show through analysis of gut bacteria in stool samples from two separate African studies enrolling children with severe malaria, and children from local communities, that children with severe malaria have gut bacteria dysbiosis. Among children with severe malaria, there is increased abundance of Enterobacteriaceae that associates with multiple clinical complications of severe malaria. Moreover, increased abundance of Escherichia coli was a predictor of post-discharge mortality. Metagenome analysis identify elevated metabolic pathways and genes supporting …

Provost's Scholarly Dissemination Report: October 2025, Une Office Of The Provost, Sonya Durney

UNE Provost's Reports

Scholarly dissemination report of UNE-authored publications during the period of May through October, 2025. Prepared for the Academic, Student, and Research Affairs Committee Report November 2025.

Provost’S Media Report May 1 – Oct. 9, 2025, Une Office Of The Provost

UNE Provost's Reports

Report of UNE media appearances during the period of May 1, 2025 through October 9, 2025. Prepared for the Academic, Student, and Research Affairs Committee Report November 2025.

Numerous Emerging Applications In N-Cylindrical Fuzzy Neutrosophic Topological Spaces, Basker P, Vennila J, Prakash V S, Ranjitha M, Shivakumar B. N, Thenmozhi K

Neutrosophic Sets and Systems

No abstract provided.

Gamma Sigma Delta, Nebraska Chapter Newsletter, Issue #68 November 2025

Gamma Sigma Delta, Nebraska Chapter: Newsletters

President's message, Deb VanOverbeke
Membership Information
2025 Outstanding Graduate Student Award Nomination Solicitation
2025 Teaching Award nomination solicitation
2025 Research Award nomination solicitation
2025 Extension Award nomination solicitation
2025 Award of Merit nomination solicitation
Gamma Sigma Delta Committees 2025
Annual Dues Notice
Membership Info and Dues
Student Award Fund solicitation
In Memoriam: Wayne W. Oberg (September 8, 1948 - February 21, 2025); Robert M. "Bob" Scriven (June 26, 1936 - August 29, 2025)
Pledge and Honor Cords
Save the Date: Initiation and Awards Reception

Oesophageal Cancer And Its Associated Factors Among Patients Attending Surgical And Oncology Clinics At Garissa County Referral Hospital, Kenya: A Case-Control Study, Abdi Bashir, Moses Ngari, Berrick Otieno, Makorani Y’Dhidha-A-Mjidho, Osman Abdullahi, Symon Kariuki

Institute for Human Development, East Africa

Background Oesophageal cancer (EC) is a common cause of cancer mortality. Evidence on the burden, risk factors and treatment outcomes is limited in low-income and middle-income countries. This study aimed to describe the features of EC cases and determine associated factors among patients attending surgical and oncology clinics in Garissa County Referral Hospital (GCRH).

Methods We conducted a case–control study in which cases were patients with EC and positive histological confirmation and controls were patients admitted to GCRH for other diseases. Data on exposures were extracted from patient files. Data on tobacco and alcohol use were based on current or …

Multiscale 3d Whole Joint Cellular And Molecular Mapping Reveals Disease-Specific Neurovascular Plasticity Underlying The Structure-Pain Relationship, Peng Chen, Jiaxin Chai, Abirami Soundararajan, R. Glenn Hepfer, Benjamin Kheyfets, Jiaxin Hu, Ishraq Alshanqiti, Swarnalakshmi Raman, Ikue Tosa, Jun Tae Huh, Matthew Yee, Brooke J. Damon, Shangping Wang, Yu Shin Kim, Man-Kyo Chung, Mildred C. Embree, Janice S. Lee, Tong Ye, Hai Yao

Publications

Understanding musculoskeletal joints from a 3D multiscale perspective, from molecular to anatomical levels, is essential for resolving the confounding relationships between structure and pain, elucidating mechanisms regulating joint health and diseases, and developing new treatment strategies. Here, a musculoskeletal joint immunostaining and clearing (MUSIC) method specifically developed to overcome key challenges of immunostaining and optical clearing of intact joints are introduced. Coupled with large-field light sheet microscopy, this approach achieves 3D high-resolution, microscale neurovascular mapping within the context of whole-joint anatomy without the need for image coregistration across various joints, including temporomandibular joints, knees, and spines, and multiple species, including …

Investigating The Effect Of Nacl Stress In Raphanus Sativus, Allison Norton

Undergraduate Research

Presentation at the Arkansas INBRE Research Conference, November 7-8, 2025

Investigating The Effect Of Cacl2 Stress In Raphanus Sativus, Justin Contreras-Portillo, Stephanie N. Nelms, Kai Herring, Amanda Munoz, Gisel Cardenas, Grace Cogswell, Tatum Simms, Aniruddha Acharya

Undergraduate Research

Presented by Justin Contreras-Portillo at the Arkansas INBRE Conference on November 7-8, 2025.

Avasopasem Manganese Treatment For Severe Oral Mucositis From Chemoradiotherapy For Locally Advanced Head And Neck Cancer: Phase 3 Randomized Controlled Trial (Roman), Carryn Anderson, Christopher M. Lee, Joseph Randall Kelley, Gary V. Walker, Neal E. Dunlap, Voichita Bar-Ad, Douglas A. Miller, Vernon J. King, Abhinand V. Peddada, Douglas F. Ciuba, Francois Vincent, Brian C. Muzyka, Amanda Lynn Gillespie-Twardy, Stephen T. Sonis, Jon Holmlund, Robert A Beardsley, Eugene P Kennedy, Deborah Saunders

Jefferson Hospital Staff Papers and Presentations

BACKGROUND: Of patients who receive standard concomitant chemoradiation (CRT; intensity-modulated radiation therapy [IMRT] plus cisplatin) for locally advanced head and neck cancer (HNC), approximately two-thirds will develop severe oral mucositis (SOM), limiting their ability to eat solids (WHO grade 3) or drink liquids (WHO grade 4). In a randomized, double-blind phase 2b trial, avasopasem manganese substantially reduced duration and incidence of SOM versus placebo. This phase 3 trial further assessed avasopasem's reduction of SOM due to CRT.

METHODS: In this double-blind, placebo-controlled trial (Clinicaltrials.gov: NCT03689712), patients receiving 60-72 Gy IMRT (>50 Gy to ≥2 oral mucosal sites) plus cisplatin …

Photochemical And Electrochemical Assessment Of Uio-66-Nh₂/G-C₃N₄ Thin-Film Heterostructures As Potential Candidates For Hydrogen Evolution: An Experimental Study Augmented By Dft Insights, Nour Abouseada, Maryam Galal, Sameh O. Abdellatif, Khaled Kirah

Electrical Engineering

The global shift towards carbon-neutral energy systems has catalyzed an intensified focus on sustainable hydrogen production, with photo and electrochemical water splitting emerging as a particularly promising pathway. This study elucidates the design, simulation, and synthesis of advanced photo and electrocatalytic materials tailored for the hydrogen evolution reaction (HER), concentrating on heterostructures formed by zirconium-based metal-organic frameworks (MOFs)— specifically, UiO-66 and its amine-functionalized derivative, UiO-66-NH₂—in conjunction with graphitic carbon nitride (g-C₃N₄). Employing density functional theory (DFT) simulations, we pre-screened the electronic properties of the MOFs, revealing that amine functionalization significantly narrows the bandgap and optimizes band alignment, thereby enhancing photocatalytic …

New Judicial Federalism And The Establishment Clause: Classroom Ten Commandments As A Case Study In State Constitutional Protection, Caroline Mala Corbin

Articles

Louisiana recently enacted a law requiring a Ten Commandments display in every public school classroom from kindergarten to college. Forty-five years ago, the U.S. Supreme Court ruled that a nearly identical attempt to introduce Christianity into the public schools violated the Establishment Clause—the clause in the U.S. Constitution’s First Amendment that requires some degree of separation between church and state.

Unfortunately, the U.S. Supreme Court has since reduced the Establishment Clause to a shadow of its former self. It replaced doctrinal tests that protected religious minorities with a history and tradition test that is easily manipulated and that presumes the …

Variation In Cycling Exercise Mechanical Efficiency In The Heritage Family Study, Angelo Tremblay, Claude Bouchard, Mark A. Sarzynski Facsm, James S. Skinner, Élisa Marin-Couture, Patrick Schrauwen, Guy Thibault, Marie-Eve Mathieu, Louis Pérusse

Faculty Publications

The objectives of the study were to assess the effects of cycling endurance exercise training and sex on cycling exercise mechanical efficiency (ME) and to explore its associations with body composition, glycemic profile, and skeletal muscle characteristics. Subjects were males (n = 371) and females (n = 465) of European (ED) and African descent (AD) of the HERITAGE Family Study. The measurements were repeated after a 20-week controlled endurance exercise program. A substudy involving 78 participants from 19 ED families was used to evaluate associations between skeletal muscle traits and variations in ME. An increase in ME of …

Prenatal Metabolomics Analysis And Fetal Congenital Anomalies And Genetic Conditions: A Review Of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, Tracy Ashby, Ignatia B Van Den Veyver

Library Staff Publications

Fetal congenital anomalies and genetic disorders complicate 3%-5% of pregnancies and can have a significant impact on pregnancy outcomes. Precise and individualized prenatal diagnosis is crucial for effective counseling and management. The identification of new biomarkers holds promise for enhancing prenatal screening, diagnosis, and prognostic counseling in affected pregnancies. Recently, metabolomics has emerged as a potential adjunct in the interpretation of genetic variants identified through genome-wide sequencing for rare genetic conditions. To assess the potential of metabolomic profiling as a functional assay capable of providing deeper insights into the pathological processes and genetic findings associated with prenatal congenital anomalies, we …

Thalamocortical Structural Covariation Networks Are Related To Familial Risk For Schizophrenia In The Context Of Lower Nuclei Volume Estimates In Patients: An Enigma Study, Annalisa Lella, Linda A. Antonucci, Roberta Passiatore, Loredana Bellantuono, Pierluigi Selvaggi, Teresa Popolizio, Guido Di Sciascio, Alessandro Saponaro, Patrizia Ricci, John Blangero

School of Medicine Publications

Background

Structural brain differences in the thalamus and the cortex have been widely reported in schizophrenia (SCZ) relative to neurotypical control individuals (NCs). Most previous studies examined the thalamusas a whole as a single region of interest. In addition, findings in individuals at familial high risk for SCZ (FHRs) remain inconclusive. Here, we investigated whether local and network-wide thalamic-related structural alterations vary as a function of familial risk for SCZ.

Methods

Structural magnetic resonance imaging scans were obtained from 5197 participants (NC, n = 3409; FHR, n = 257; SCZ, n = 1531) across 32 cross-sectional samples within the …

Une Library Services Quarterly Report November 2025, Une Library Services

Quarterly Reports

Highlights of accomplishments of the University of New England's Library Services department.

Impact Of Lignin Content On Decomposition Rates, Lindsey Powell, Olivia Fawkes, Moses Elijah Cadawas, Isaac Paul Dent, Darlene Panvini

Science University Research Symposium (SURS)

This study aimed to analyze decomposition rates of plants containing different amounts of lignin. Lignin can be found within cell wall structures in plants and aids in natural rigidity. Opuntia humifusa was chosen to represent plants with high levels of lignin, and Allium schoenoprasum was chosen in contrast because of its significantly lower levels of lignin. Due to these characteristics, A. schoenoprasum is hypothesized to decompose at a quicker rate than O. humifusa. To test this hypothesis, eight samples of O. humifusa and eight samples of A. schoenoprasum were placed in litter bags to prevent macroorganisms from aiding in …