Digital Commons Network^™

[Kadel] Understanding Aging In Worms Using Boolean Modeling, Brandilyn Stigler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Histamine And Serotonin Impact Anopheles Stephensi Population Dynamics And Malaria Transmission: Perspectives From Mathematical Modeling, Michael Robert

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Quantification Of Parameters To Predict The Rupture Of Intracranial Saccular Aneurysms Using Physics Informed Neural Networks, Alonso Gabriel Ogueda, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

[Lele] Early Careers In Mathematical Biology "Mathematical Analysis Of Exposure-Dependent Transmission With Environmental Reservoirs", Mohammad Mihrab Uddin Chowdhury, Angela Peace, Matthew J. Gray

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Representing Ewe-Lamb Contact Dynamics In An Agent-Based Model Of Enzootic Abortion Of Ewes, Kelly R. Buch, Cara J. Sulyok

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

[Kadel] A Multilevel Extension Of Boolean Networks Captures Topologically-Stable Hybrid Attractors, Kishore Hari

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Metapopulation Model For Oyster Restoration, Leah Shaw

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

[Lele] Understanding The Dynamics Of Legionnaires’ Disease Through Mathematical Modeling, Lihong Zhao

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

[Chu] Modelling The Effect Of Disturbed Blood-Feeding On Mosquito-Borne Disease Transmission, Kyle Dahlin, Michael Robert, Lauren Childs

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

2025-26 Women In Science Conference Schedule (Pdf), Lynn University

Women in Science Conference

No abstract provided.

Sglt2 Inhibitors For Non-Diabetic Patients With Chronic Kidney Disease: A Literature Review, Mostafa Mohrag

University of Bisha Journal for Basic and Applied Sciences

Introduction: Chronic kidney disease (CKD) pertains a sizeable burden on healthcare systems worldwide and is associated with significant morbidity and mortality. Recently, there has been compelling evidence associating SGLT2i usage with improved renal function and delayed progression in underlying CKD. Objective: To assess the efficacy of SGLT2i on the development of CKD in non-diabetic patients, with special attention to their efficacy, side effects, and “hard” renal outcomes such as progression to renal replacement therapy and worsening eGFR. Methodology: A broad search in the available medical databases (e.g MEDLINE, SCOPUS) was undertaken. Results: The available literature points strongly towards an overall …

Atmospheric Pressure Plasma Jet (Appj): A Review Of Producing Hydroxide (Oh) Radicals, And Wound Healing, A. E. Metawa

University of Bisha Journal for Basic and Applied Sciences

Atmospheric pressure plasma jet APPJ is one of the systems most used for producing chemical active reactions. Plasma jet generation uses various configurations, and power sources drive the discharge. Review and several chemical reactions can occur inside the plasma, producing several reactive species such as electrons, ions, and free radicals. There are different reactive species performed inside the plasma atmospheric pressure plays a role. hydroxyl (OH), these species have important effects in different applications, especially in medical and biological applications. Mechanism of producing the OH and O₃ radicals in different plasma jets. The chemical reactions govern the mechanism of …

Infrared Salient Object Detection And Classification With Deep Learning, Hamdan Alshehri, Haitham Assiri, Salahaldeen Duraibi, Yahya Alqahtani

University of Bisha Journal for Basic and Applied Sciences

As the complexity of large-scale infrared video images increases, traditional approaches for detecting conspicuous objects in these images continue to fail. An improved method for detecting prominent objects in infrared photos using deep learning has been created. The major parts of this model include the spatial feature extractor, the temporal feature extractor, the residual connection blocks, and the pixel-level classifier. The spatial feature extraction module was first used to collect the relevant spatial data. Once consistent spatial and temporal data was collected, the temporal feature extraction module was applied. The salient object recognition outcome was produced by jointly feeding the …

Native Bee Assemblages In Prescribed Fire-Managed Prairies: A Case Study From Arkansas, United States, Coleman Z. Little, Neelendra K. Joshi

Entomology and Plant Pathology Faculty Publications and Presentations

Native bee communities in Arkansas remain poorly documented, particularly within fire-managed prairie ecosystems that provide critical habitat for pollinators. This study surveyed bee assemblages at two native prairie remnants in the Arkansas River Valley, one large (Cherokee Prairie Natural Area, CPNA) and one small urban fragment (Jewel Moore Nature Reserve, JMNR), both managed using prescribed fire. Using pan trapping, we recorded 599 individuals representing 96 species across 25 genera, including 49% singletons. Despite differences in size and landscape context, both prairies supported similarly rich bee communities per sample day, with JMNR and CPNA averaging 16.1 and 13.75 species, respectively. However, …

Multiplexed Integrin Detection And Cancer Cell Classification Using Multicolor Gap-Enhanced Gold Nanorods And Machine Learning Algorithm, Suprava Shah, Reed Youngerman, Alberto Luis Rodriguez-Nieves, Mitchell Lee Taylor, William Rodney Bantom, David Thompson, Jingyi Chen, Yongmei Wang, Xiaohua Huang

Chemistry & Biochemistry Faculty Publications and Presentations

Integrins, cell-surface adhesion receptors involved in tumor progression, invasion, and metastasis, serve as crucial biomarkers for cancer diagnosis and therapeutic targeting. Multiplexed detection of integrins and cancer cell classification at the single-cell level allows for comprehensive profiling, facilitating precise identification and categorization of tumor cells that are heterogeneous in integrin expression and cell subtype. In this study, we developed a five-plex detection platform and demonstrated integrin profile for cancer cell classification leveraging surface-enhanced Raman scattering (SERS) with gap-enhanced gold nanorods (GENRs) in conjunction with advanced computational analysis. Specifically, we synthesized GENRs bearing five distinct Raman nanotags, each producing a unique …

Rbm39 Contributes To Mgmt Maintenance In Response To Temozolomide-Induced Dna Damage, Vahid Khalaj, Jack T Adams, Solmaz Aghaamiri, Servando Hernandez Vargas, Tyler M Bateman, Sukhen C Ghosh, Majid Momeny, Ali Azhdarinia

The Brown Foundation: Institute of Molecular Medicine

Resistance to alkylating chemotherapeutic agents such as temozolomide (TMZ) is a significant challenge in treating tumors with high MGMT expression, including MGMT-positive glioblastoma and neuroendocrine neoplasms. In this study, we investigated the effect of RNA-binding motif protein 39 (RBM39) downregulation on MGMT protein levels, based on prior observations suggesting an association between these two proteins. Pharmacological depletion or siRNA-mediated knockdown of RBM39 led to a marked reduction in MGMT protein levels in MGMT-expressing cancer cells. We further showed that dual targeting of RBM39 (using indisulam) and MGMT (with O6-benzylguanine) synergistically enhanced MGMT depletion. Functionally, combined indisulam and TMZ treatment significantly …

Untargeted Metabolomics Reveals Organ-Specific And Extraction-Dependent Metabolite Profiles In Endemic Tajik Species Ferula Violacea Korovin, Sylhiya Mavlonazarova, Kenneth Acosta, Rinat Abzalimov, Saidbeg Satorov, Vyacheslav Dushenkov

Publications and Research

Ferula violacea Korovin, an endemic Tajikistani plant with purported medicinal properties, remains understudied. This study employs untargeted metabolomics to characterize the metabolite profiles of ethanol extracts and juices from F. violacea roots and seeds. In total, 540 distinct metabolites are putatively identified, 419 of which are previously unreported in the Ferula genus, representing a substantial expansion of its known chemical diversity. The most abundant metabolites are terpenoids, amino acid derivatives, and alkaloids. A particularly abundant group of daucane sesquiterpenoids, sharing a common (6-methyl-azulen-4-yl) cyclohexanecarboxylate substructure, is identified, including known metabolites such as ferutidin and ferutinin. Comparative analysis reveals organ-specific metabolic …

Hyperoxia During Neonatal Cardiopulmonary Bypass Is Associated With Worse Clinical Outcomes: A Multi-Institutional Study, Asaad G Beshish, David M Kwiatkowski, Nathaniel Sznycer-Taub, John M Costello, Andrew Jergel, Scott Gillespie, Katherine Cashen, Ahmed Asfari, Maria Batsis, Jason R Buckley, Meghan M Chlebowski, Saul Flores, Nimrod Goldshtrom, Karl Migally, Kimberly I Mills, Monique R Radman, Chetana Reddy, Brittany Shutes, Christine M Riley, Sukumar Suguna Narasimhulu, Dana Mueller, Venugopal Amula, Raji Venkitachalam, Brian F Joy, Karan B Karki, Scott M Leopold, Jennifer E Schramm, Christine A Capone, Scott I Aydin, Adnan M Bakar, Kieran Leong, Agnieszka Kulikowska, Sarah Wing, Christopher W Mastropietro, Collaborative Research From The Pediatric Intensive Care Society (Core‐Pcics) Investigators

Faculty, Staff and Students Publications

Background: Exposure to supraphysiologic oxygen concentrations, or hyperoxia, during neonatal cardiopulmonary bypass (CPB) has been associated with worse outcomes in single-center studies. We aimed to describe variation in oxygen exposure during CPB and determine if hyperoxia is associated with worse outcomes in a multicenter cohort of neonates undergoing cardiac surgery.

Methods: We conducted a retrospective study of neonates who underwent surgery with CPB between January 2021 and December 2022 at 29 centers. Primary outcomes were operative mortality and major adverse cardiovascular events (MACE), which included CPR, extracorporeal support, stroke, and mortality. Logistic regression assessed the associations between median PaO2 during …

Glucagon-Like Peptide 1 Receptor Agonists And The Clinical Outcomes Of Inflammatory Bowel Disease: A Systematic Review And Meta-Analysis, Ahmed B Bayoumy, Lindsay M Clarke, Parakkal Deepak, Aakash Desai, Priya Sehgal, Uri Gorelik, Haggai Bar-Yoseph, Marie Villumsen, Chris J J Mulder, Dirk J Stenvers, Maarten E Tushuizen, Nanne K H De Boer

2020-Current year OA Pubs

BACKGROUND: Prior studies showed worse outcomes in obese inflammatory bowel disease (IBD) patients, especially those related to hospitalizations, surgery, and steroid-free remission. Glucagon-like peptide-1 receptor agonists (GLP1-RAs) have demonstrated significant metabolic benefits for patients with type 2 diabetes mellitus (T2DM) and obesity. Hence, GLP1-RAs may improve clinical outcomes in patients with IBD, especially those with obesity. The objective was to systematically evaluate the impact of GLP1-RAs on clinical outcomes in patients with IBD.

METHODS: A comprehensive literature search was performed using the databases PubMed, Embase, Web of Science, and Cochrane Library from inception to March 15, 2025. Studies reporting outcomes …

Understanding The Spread Of Black Sigatoka Disease: A Deterministic And Stochastic Modeling Approach, Bernard Asamoah Afful, Luis F. Gordillo

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling The Probability Of N Clonal Rosettes In A Bromeliaceae Genetic Individual, Erin N. Bodine, Layla K. Lammers

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling Probiotic Bacterial Control Of White-Nose Syndrome In Little Brown Bat Colonies, Bethany Droubay, Alex Capaldi

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Compartmental Model For Diurnal Atlantic Stingray Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Mathematically Modeling Stoichiometric Drivers Of Heterotrophic N2 Fixation, Corday R. Selden, Rebecca Everett, Halvor H. Halvorson, Megan E. Berberich, Luca Schenone, Angela Peace, Renn Schipper, Edwin Cruz-Rivera, James Powell, Keisuke Inomura, Robinson W. Fulweiler, Amy M. Marcarelli, J Thad Scott

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Analyzing Urban Space-Use Of White-Tailed Deer (Odocoileus Virginianus), Szandra A. Péter, Zehidul Hussain, Solena Kronstedt, Amira Roess, Jennifer Mullinax, Travis Gallo, Taylor Anderson

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Balancing Stability And Complexity In Boolean Models Of Biological Networks, Venkata Sai Narayana Bavisetty

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Compartmental Model For Periodic Animal Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Compartmental Model For Annual Blue Whale Migration, Leah Glasser, Christopher Hay-Jahans, Elena Wheatley, Rhianna Yates

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Spatial Strategies In Ants: Modeling Polydomy, Saya Zeleznik, Fred Adler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Optimizing The Distribution Of Fruiting Agave On Bat-Friendly Tequila Plantations, Grace Gorreck, Clarissa Azurin, Lois Carpenter

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.