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New Common Fixed Points For Total Asymptotically Nonexpansive Mapping In Cat(0) Space, Ahmed Jameel Kadhim Dec 2021

New Common Fixed Points For Total Asymptotically Nonexpansive Mapping In Cat(0) Space, Ahmed Jameel Kadhim

Baghdad Science Journal

Strong and ∆-convergence for a two-step iteration process utilizing asymptotically nonexpansive and total asymptotically nonexpansive noneslf mappings in the CAT(0) spaces have been studied. As well, several strong convergence theorems under semi-compact and condition (M) have been proved. Our results improve and extend numerous familiar results from the existing literature.


Biological Evaluation And Theoretical Study Of Bi-Dentate Ligand For Amoxicillin Derivative With Some Metal Ions, Sahar S. Hassan, Nidhal M. Hassan, Shaymaa Rajab Baqer, Asmaa M. Saleh Dec 2021

Biological Evaluation And Theoretical Study Of Bi-Dentate Ligand For Amoxicillin Derivative With Some Metal Ions, Sahar S. Hassan, Nidhal M. Hassan, Shaymaa Rajab Baqer, Asmaa M. Saleh

Baghdad Science Journal

In this paper, the complexes of Shiff base of Methyl -6-[2-(diphenylmethylene)amino)-2-(4-hydroxyphenyl)acetamido]-2,2-dimethyl-5-oxo-1-thia-4-azabicyclo[3.2.0]heptane-3-carboxylate (L) with Cobalt(II), Nickel(II), Cupper(II) and Zinc(II) have been prepared. The compounds have been characterized by different means such as FT-IR, UV-Vis, magnetic moment, elemental microanalyses (C.H.N), atomic absorption, and molar conductance. It is obvious when looking at the spectral study that the overall complexes obtained as monomeric structure as well as the metals center moieties are two-coordinated with octahedral geometry excepting Co complexes that existed as a tetrahedral geometry. Hyper Chem-8.0.7 program was employed, after calculating the heat of formation (ΔH°f), binding energy (ΔEb), dipole moment( µ ), …


A Systematic Review Of Parent Training Effects Children's Use Of Augmentative And Alternative Communication Systems, Mia Constransitch Dec 2021

A Systematic Review Of Parent Training Effects Children's Use Of Augmentative And Alternative Communication Systems, Mia Constransitch

Undergraduate Honors Theses

Augmentative and Alternative Communication (AAC) are communication systems used when someone cannot express their needs with naturally spoken speech. For children who use AAC, parent training is an essential part because it teaches the parents how to use the device and encourages their child to use the device. A systematic review was completed to explore the literature regarding parent training for parents whose children are AAC users, and how the training impacts the child's success using the AAC system. The results from this can be used to explore if parent training is effective and if there is a need for …


Ahr Activation And T-Cell Expression In Eyfp Mice, Claire M. Hamilton Dec 2021

Ahr Activation And T-Cell Expression In Eyfp Mice, Claire M. Hamilton

Undergraduate Honors Theses

The objective of this study was to determine what blood cell types express the B lymphocyte-induced maturation protein-1 (BLIMP-1) gene. Such findings would be instrumental in research regarding the aryl hydrocarbon receptor (AhR) which is important in immune responses. The experimental model was a transgenic mouse that expresses the enhanced yellow fluorescent protein (eYFP) under the control of the BLIMP-1 promoter. Testing was carried out in two parts; (1) testing mice for eYFP presence and (2) testing mice for phenotypic cell markers. Cell samples were tested via flow cytometry. During phase one of testing it was found that positive mice …


Spatial Distribution Of Conspecific Genotypes Within Chimeras Of The Branching Coral Stylophora Pistillata, Gabriele Guerrini, Dor Shefy, Jacob Douek, Nadav Shashar, Tamar L. Goulet, Baruch Rinkevich Dec 2021

Spatial Distribution Of Conspecific Genotypes Within Chimeras Of The Branching Coral Stylophora Pistillata, Gabriele Guerrini, Dor Shefy, Jacob Douek, Nadav Shashar, Tamar L. Goulet, Baruch Rinkevich

Faculty and Student Publications

Chimerism is a coalescence of conspecific genotypes. Although common in nature, fundamental knowledge, such as the spatial distribution of the genotypes within chimeras, is lacking. Hence, we investigated the spatial distribution of conspecific genotypes within the brooding coral Stylophora pistillata, a common species throughout the Indo-Pacific and Red Sea. From eight gravid colonies, we collected planula larvae that settled in aggregates, forming 2–3 partner chimeras. Coral chimeras grew in situ for up to 25 months. Nine chimeras (8 kin, 1 non-related genotypes) were sectioned into 7–17 fragments (6–26 polyps/fragment), and genotyped using eight microsatellite loci. The discrimination power of each …


Rcb Initiates Arabidopsis Thermomorphogenesis By Stabilizing The Thermoregulator Pif4 In The Daytime, Yongjian Qiu, Elise K. Pasoreck, Chan Yul Yoo, Jiangman He, He Wang, Abhishesh Bajracharya, Meina Li, Haley D. Larsen, Stacey Cheung, Meng Chen Dec 2021

Rcb Initiates Arabidopsis Thermomorphogenesis By Stabilizing The Thermoregulator Pif4 In The Daytime, Yongjian Qiu, Elise K. Pasoreck, Chan Yul Yoo, Jiangman He, He Wang, Abhishesh Bajracharya, Meina Li, Haley D. Larsen, Stacey Cheung, Meng Chen

Faculty and Student Publications

Daytime warm temperature elicits thermomorphogenesis in Arabidopsis by stabilizing the central thermoregulator PHYTOCHROME INTERACTING transcription FACTOR 4 (PIF4), whose degradation is otherwise promoted by the photoreceptor and thermosensor phytochrome B. PIF4 stabilization in the light requires a transcriptional activator, HEMERA (HMR), and is abrogated when HMR’s transactivation activity is impaired in hmr-22. Here, we report the identification of a hmr-22 suppressor mutant, rcb-101, which surprisingly carries an A275V mutation in REGULATOR OF CHLOROPLAST BIOGENESIS (RCB). rcb-101/hmr-22 restores thermoresponsive PIF4 accumulation and reverts the defects of hmr-22 in chloroplast biogenesis and photomorphogenesis. Strikingly, similar to hmr, the null rcb-10 mutant impedes …


Climate And Seasonality Drive The Richness And Composition Of Tropical Fungal Endophytes At A Landscape Scale, Shuzo Oita, Alicia Ibáñez, François Lutzoni, Jolanta Miadlikowska, József Geml, Louise A. Lewis, Erik F. Y. Hom, Ignazio Carbone, Jana M. U’Ren, A. Elizabeth Arnold Dec 2021

Climate And Seasonality Drive The Richness And Composition Of Tropical Fungal Endophytes At A Landscape Scale, Shuzo Oita, Alicia Ibáñez, François Lutzoni, Jolanta Miadlikowska, József Geml, Louise A. Lewis, Erik F. Y. Hom, Ignazio Carbone, Jana M. U’Ren, A. Elizabeth Arnold

Faculty and Student Publications

Understanding how species-rich communities persist is a foundational question in ecology. In tropical forests, tree diversity is structured by edaphic factors, climate, and biotic interactions, with seasonality playing an essential role at landscape scales: wetter and less seasonal forests typically harbor higher tree diversity than more seasonal forests. We posited that the abiotic factors shaping tree diversity extend to hyperdiverse symbionts in leaves—fungal endophytes—that influence plant health, function, and resilience to stress. Through surveys in forests across Panama that considered climate, seasonality, and covarying biotic factors, we demonstrate that endophyte richness varies negatively with temperature seasonality. Endophyte community structure and …


Publisher Correction: The Genome Of The Stable Fly, Stomoxys Calcitrans, Reveals Potential Mechanisms Underlying Reproduction, Host Interactions, And Novel Targets For Pest Control (Bmc Biology, (2021), 19, 1, (41), 10.1186/S12915-021-00975-9), Pia U. Olafson, Serap Aksoy, Geoffrey M. Attardo, Greta Buckmeier, Xiaoting Chen, Craig J. Coates, Megan Davis, Justin Dykema, Scott J. Emrich, Markus Friedrich, Christopher J. Holmes, Panagiotis Ioannidis, Evan N. Jansen, Emily C. Jennings, Daniel Lawson, Ellen O. Martinson, Gareth L. Maslen, Richard P. Meisel, Terence D. Murphy, Dana Nayduch, David R. Nelson, Kennan J. Oyen, Tyler J. Raszick, José M.C. Ribeiro, Hugh M. Robertson, Andrew J. Rosendale, Timothy B. Sackton, Perot Saelao, Sonja L. Swiger, Sing Hoi Sze, Aaron M. Tarone, David B. Taylor, Wesley C. Warren, Robert M. Waterhouse, Matthew T. Weirauch, John H. Werren, Richard K. Wilson, Evgeny M. Zdobnov, Joshua B. Benoit Dec 2021

Publisher Correction: The Genome Of The Stable Fly, Stomoxys Calcitrans, Reveals Potential Mechanisms Underlying Reproduction, Host Interactions, And Novel Targets For Pest Control (Bmc Biology, (2021), 19, 1, (41), 10.1186/S12915-021-00975-9), Pia U. Olafson, Serap Aksoy, Geoffrey M. Attardo, Greta Buckmeier, Xiaoting Chen, Craig J. Coates, Megan Davis, Justin Dykema, Scott J. Emrich, Markus Friedrich, Christopher J. Holmes, Panagiotis Ioannidis, Evan N. Jansen, Emily C. Jennings, Daniel Lawson, Ellen O. Martinson, Gareth L. Maslen, Richard P. Meisel, Terence D. Murphy, Dana Nayduch, David R. Nelson, Kennan J. Oyen, Tyler J. Raszick, José M.C. Ribeiro, Hugh M. Robertson, Andrew J. Rosendale, Timothy B. Sackton, Perot Saelao, Sonja L. Swiger, Sing Hoi Sze, Aaron M. Tarone, David B. Taylor, Wesley C. Warren, Robert M. Waterhouse, Matthew T. Weirauch, John H. Werren, Richard K. Wilson, Evgeny M. Zdobnov, Joshua B. Benoit

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Following publication of the original article [1], it was reported that the article copyright was incorrect. The correct copyright statement is: © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021. The original article [1] has been corrected.


Genetic Fingerprinting And Aflatoxin Production Of Aspergillus Section Flavi Associated With Groundnut In Eastern Ethiopia, Abdi Mohammed, Paola C. Faustinelli, Alemayehu Chala, Mashilla Dejene, Chemeda Fininsa, Amare Ayalew, Chris O. Ojiewo, David A. Hoisington, Victor S. Sobolev, Jaime Martínez-Castillo, Renee S. Arias Dec 2021

Genetic Fingerprinting And Aflatoxin Production Of Aspergillus Section Flavi Associated With Groundnut In Eastern Ethiopia, Abdi Mohammed, Paola C. Faustinelli, Alemayehu Chala, Mashilla Dejene, Chemeda Fininsa, Amare Ayalew, Chris O. Ojiewo, David A. Hoisington, Victor S. Sobolev, Jaime Martínez-Castillo, Renee S. Arias

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: Aspergillus species cause aflatoxin contamination in groundnut kernels, being a health threat in agricultural products and leading to commodity rejection by domestic and international markets. Presence of Aspergillus flavus and A. parasiticus colonizing groundnut in eastern Ethiopia, as well as presence of aflatoxins have been reported, though in this region, no genetic studies have been done of these species in relation to their aflatoxin production. Results: In this study, 145 Aspergillus isolates obtained from groundnut kernels in eastern Ethiopia were genetically fingerprinted using 23 Insertion/Deletion (InDel) markers within the aflatoxin-biosynthesis gene cluster (ABC), identifying 133 ABC genotypes. Eighty-four isolates …


Spatiotemporal Pattern Detection With Neuromorphic Circuits, Robert C. Ivans Dec 2021

Spatiotemporal Pattern Detection With Neuromorphic Circuits, Robert C. Ivans

Boise State University Theses and Dissertations

In this dissertation, neuromorphic circuits are used to implement spiking neural networks in order to detect spatiotemporal patterns. Unsupervised training and detection-by-design techniques were used to attain the appropriate connectomes and perform pattern detection.

Unsupervised training was performed by feeding random digital spikes with a repeating embedded spatiotemporal pattern to a spiking neural network composed of leaky integrate-and-fire neurons and memristor-R(t) element circuits which implement spike-timing-dependent plasticity learning rules.

Detection-by-design was achieved using neuromporphic circuits and digital logic gates. When detection-by-design was achieved using both neuromorphic circuits and digital logic gates, a network was created of spatiotemporal pattern detector circuits, …


Nuclear Envelope Mechanobiology: Linking The Nuclear Structure And Function, Matthew Goelzer, Julianna Goelzer, Matthew L. Ferguson, Corey P. Neu, Gunes Uzer Dec 2021

Nuclear Envelope Mechanobiology: Linking The Nuclear Structure And Function, Matthew Goelzer, Julianna Goelzer, Matthew L. Ferguson, Corey P. Neu, Gunes Uzer

Mechanical and Biomedical Engineering Faculty Publications and Presentations

The nucleus, central to cellular activity, relies on both direct mechanical input as well as its molecular transducers to sense external stimuli and respond by regulating intra-nuclear chromatin organization that determines cell function and fate. In mesenchymal stem cells of musculoskeletal tissues, changes in nuclear structures are emerging as a key modulator of their differentiation and proliferation programs. In this review we will first introduce the structural elements of the nucleoskeleton and discuss the current literature on how nuclear structure and signaling are altered in relation to environmental and tissue level mechanical cues. We will focus on state-of-the-art techniques to …


2021 Summer-Fall Graduate Recognition Program, Propulsion Research Center, Robert Frederick Dec 2021

2021 Summer-Fall Graduate Recognition Program, Propulsion Research Center, Robert Frederick

PRC Graduate Recognition

This program includes the graduate recognition program for summer and fall 2021. Includes photographs, upcoming events, recent publications, and student profiles.


Developing Strategy For A Successful Antioxidant, Anticancer Activity Via An Improved Method Prepared To Porous Silicon Nanoparticles, Kareem Jawad, Butheina Hasson Dec 2021

Developing Strategy For A Successful Antioxidant, Anticancer Activity Via An Improved Method Prepared To Porous Silicon Nanoparticles, Kareem Jawad, Butheina Hasson

Journal of Applied Sciences and Nanotechnology

Porous silicon nanoparticles, or PSNPs, are one of the most common NPS with distinct characteristics. PSNPs were created using an enhanced approach known as the electrochemical etching process. The nanoparticles were treated with a post-laser to obtain the nanoparticles, which were subsequently analyzed using (SEM), (UV-Vis), and (XRD). The size refers to porous silicon with a nanostructure. Because of the differences in interaction between the HF electrolyzed and silicon and crystal structure, PS (100) offers better NP properties than directional silicon (111). PSNPs' antioxidant activity was measured using the DPPH test, while cytotoxicity was measured using the MTT assay on …


Sequencing Analysis Of Cvac Gene In Acinetobacter Baumannii That Isolates From Different Infections, Rana Abdullah, Rasha Ahmed Dec 2021

Sequencing Analysis Of Cvac Gene In Acinetobacter Baumannii That Isolates From Different Infections, Rana Abdullah, Rasha Ahmed

Journal of Applied Sciences and Nanotechnology

Acinetobacter baumannii is one of the opportunistic nurses responsible for many acquired infections in hospitals due to its ability to resist many antibiotics. This is one of the problems facing hospitals in the world. Identification of the cvaC gene and sequence analysis in Acinetobacter baumannii isolates from various infections, and mutation detection in this gene. From 1st of September to 30th of November, 2016, 200 Acinetobacter baumannii isolates were obtained from various clinical samples. Follow fifty isolates from blood, twenty isolates from urinary tract infections, thirty isolates from wound infections, forty isolates from burn infections and twenty-five isolates from stool …


Evidence Of Antioxidant Activity Of Novel L-Glutaminase Purified From L. Gasseri Brlhm, Butheina Hasson, Likaa Mahdi, Rajwa Essa Dec 2021

Evidence Of Antioxidant Activity Of Novel L-Glutaminase Purified From L. Gasseri Brlhm, Butheina Hasson, Likaa Mahdi, Rajwa Essa

Journal of Applied Sciences and Nanotechnology

Probiotic strains have the potential to be used as bio-preservatives and functional radical scavenging treatments in the future.  Antioxidant tests, including DPPH radical scavenging, were used to evaluate the antioxidant effects of extracellular L- Glutaminase isolated from L. gasseri BRLHM. Parameters for the promoted production of the enzyme under minimal production media were optimized.    The importance of this study lies in enhancing the production of the L- Glutaminase isolated from L. gasseri BRLHM with a high activity using these L. gasseri bacterial as antioxidant activity. In ion-exchange chromatography, the specific activity was 14.7U/mg protein, with 58.8% yield and 4.6 purification …


The Effect Of Current Density On The Properties Of Porous Silicon Gas Sensor For Ethanol And Methanol Vapour Detection, Muna Kareem, Adi M., Haitham Hussein Dec 2021

The Effect Of Current Density On The Properties Of Porous Silicon Gas Sensor For Ethanol And Methanol Vapour Detection, Muna Kareem, Adi M., Haitham Hussein

Journal of Applied Sciences and Nanotechnology

In this paper, Gas sensors for ethanol and methanol were created utilizing porous silicon (PSi).n-type silicon was employed for all PSi samples, photo-electrochemical etching technique (PECE) was used to prepare porous surface. The intensity of the three etchings current densities was 12, 24 and 30 mA / cm2, with 40% hydrofluoric acid concentration (HF) and a time of etching 10 minutes. Porous silicon (100) has been strictly studied by the structure and formation of surface bonding of the PSi layer; the structural properties, morphological characteristics, pore diameter, and roughness were described using X-ray diffraction (XRD), atomic force microscopy (AFM) and …


Obtaining L - Glutamate Oxidase Enzyme From Streptomyces And Estimation Its Toxicity On Blood Components, Dina Abdul Hameed, Entesar Ali Dec 2021

Obtaining L - Glutamate Oxidase Enzyme From Streptomyces And Estimation Its Toxicity On Blood Components, Dina Abdul Hameed, Entesar Ali

Journal of Applied Sciences and Nanotechnology

Streptomyces was isolated from the soil and then tested to diagnose morphologically and microscopically. Also, cultivated in the production medium of the L-glutamate oxidase enzyme, for which the wheat bran culture media was used, and then the extracellular L-glutamate oxidase enzyme was extracted using a cooling centrifuge at 8000 rpm for 20 minutes. The optimal temperature and pH for the production of the enzyme’s conditions were studied. Research results revealed that the optimum temperature for enzyme production was 30°C, and the best pH for the enzyme’s production was 7.0 later on, the enzyme was purified using common purification techniques represented …


Preparation Of V2o5 And Sno2 Nanoparticles And Their Application As Pollutant Removal, Zahra Hassan, Rashed Rasheed Dec 2021

Preparation Of V2o5 And Sno2 Nanoparticles And Their Application As Pollutant Removal, Zahra Hassan, Rashed Rasheed

Journal of Applied Sciences and Nanotechnology

Vanadium pentoxide and Tin dioxide nanoparticles were prepared by hydrothermal methods to remove methylene blue (MB) and bromothymol blue (BTB) dyes). First the prepared nanoparticles were heated at different temperature (90 oC and 500 oC). Then these nanoparticles were characterized by different methods such as UV/Visible, FT-IR Spectroscopy, X-Ray Diffraction (XRD), Atomic Force Microscopy (AFM), and Scanning Electron Microscopy (SEM). Our results explain that vanadium pentoxide nanoparticles appeared high remove activity against both types of organic dyes (MB and BTB) compared to tin dioxide nanoparticles. Furthermore,vanadium pentoxide heating at 90 oC has grain size (86.02 nm) more than that of …


A Generalization Of The Concave Integral In Terms Of Decomposition Of The Integrated Function For Bipolar Scales, Fadheela Kareem, Jabbar Abbas Dec 2021

A Generalization Of The Concave Integral In Terms Of Decomposition Of The Integrated Function For Bipolar Scales, Fadheela Kareem, Jabbar Abbas

Journal of Applied Sciences and Nanotechnology

In the context of the multiple-criteria decision aid (MCDA), several fuzzy integrals concerning capacities (non-additive measures) have been introduced by various researchers in the last sixty years.  Recently, Lehrer has proposed a new integral for capacities known as concave integral. The concave integral is based on the decomposition of random variables into simple ingredients. The concave integral concerning capacity is defined as the maximum value obtained among all its decompositions. The paper aims to model a new integration based on the decomposition of random variables into simple ingredients for multi-criteria decision making support when underlying scales are bipolar.  This paper …


Iris Magazine: Omens, Iris Magazine Staff Dec 2021

Iris Magazine: Omens, Iris Magazine Staff

Iris Magazine

ARTICLES

PAGE 1-3…….HUMANIZING GENESEO, MADISON WRIGHT AND NEVAEH TUCKER

PAGE 4-5…….STRIPPING MENSTRUATION OF GENDERED LANGUAGE, SARAH SHARPLES

CREATIVE ENTRIES

PAGE 1……….FIREWATCH, SAGE KEARNEY

PAGE 2……….MESS, LIDABEL GUZMAN AVILA

PAGE 3……….SELF SACRIFICIAL, LIDABEL GUZMAN AVILA

PAGE 4-6…….LIFE AFTER, AL TEJERA

PAGE 7-8…….SERAPH, SOL RIVERA

PAGE 9……….PLAYLIST, KAMAL LYTHCOTT

VISUAL ART

PAGE 1……….CEOS ON SUNDAYS, AL TEJERA

PAGE 2……….CHURCH, MIKAYLA ANDERSON

PAGE 3……….ENTRANCED, NOEL GUIDRY

PAGE 4……….THE WITCHING HOUR, NOEL GUIDRY

PAGE 5……….IF YOU WORE THESE SHORTS AS A KID YOU’RE GAY NOW, ANONYMOUS

PAGE 6……….LION, SIERRE ETKIN


December 2021 News Releases, University Of Montana--Missoula. Office Of University Relations Dec 2021

December 2021 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.


Science Communication In The Time Of Covid-19, Inez Z. Ponce De Leon Dec 2021

Science Communication In The Time Of Covid-19, Inez Z. Ponce De Leon

Department of Communication Faculty Publications

No abstract provided.


Detecting Gsr Indicative Particles On Decayed Bones Using A Novel Field Kit, Sven Engling Dec 2021

Detecting Gsr Indicative Particles On Decayed Bones Using A Novel Field Kit, Sven Engling

Student Theses

Decomposed human remains are complex forensic puzzles, escalating in difficulty as the remains’ age obscures evidence, like trauma. Research has shown that scanning electron microscopes with energy dispersive X-ray spectrometers (SEM-EDX) are capable of detecting and identifying gunshot residue (GSR) particles on bones. However, SEM-EDX work is time consuming, expensive, and not accessible to every forensic department. Therefore, a preliminary field test capable of detecting GSR indicative particles, like lead, could save departments money and assist in trauma identification. This study examines the viability of using either the 3M Lead Check Test swabs or a sodium rhodizonate solution as part …


Development And Validation Of A Method For The Determination Of Designer Benzodiazepines In Hair By Liquid Chromatography Tandem Mass Spectrometry (Lc-Ms/Ms), Laura C. Defreitas Dec 2021

Development And Validation Of A Method For The Determination Of Designer Benzodiazepines In Hair By Liquid Chromatography Tandem Mass Spectrometry (Lc-Ms/Ms), Laura C. Defreitas

Student Theses

In recent years, new designer benzodiazepines have become a challenge in forensic toxicology. These substances are analogues of the classic benzodiazepines, but their pharmacology is not well known, and many of them have been associated with overdoses and deaths. As a result, there has been a surge in efforts to develop ways to accurately test for these compounds in different biological matrices. This study focused to develop and validate a method for determining 17 new designer benzodiazepines in hair by liquid chromatography tandem mass spectrometry (LC-MS/MS). Hair samples were decontaminated, pulverized, and 20 mg of the sample was incubated in …


Impact Of Blood Collection Tubes In Cannabinoid Quantitative Analysis, Tega E. Obruche-Akponah Dec 2021

Impact Of Blood Collection Tubes In Cannabinoid Quantitative Analysis, Tega E. Obruche-Akponah

Student Theses

In forensic toxicological cases, sample stability and storage are pivotal for obtaining adequate analytical results. Currently, limited information is available about the impact of different preservatives and anticoagulants present in the blood tubes used in the collection of blood samples containing cannabinoids. This study investigated the impact of sodium fluoride (gray top) and sodium citrate (blue top) blood collection tubes on the concentrations of tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN) and 5 THC metabolites (THC-OH, THC-COOH, THC-diOH, THC-glucuronide, THCCOOH-glucuronide) in whole blood samples, stored at room temperature, 4ºC and -20ºC for up to 3.5 months. The samples were extracted using …


Support For Militant U.S. Foreign Policy: The Role Of Authoritarianism And International Xenophobia, Brandon M. Garcia Dec 2021

Support For Militant U.S. Foreign Policy: The Role Of Authoritarianism And International Xenophobia, Brandon M. Garcia

Student Theses

Right-Wing Authoritarianism (RWA) has been studied extensively in the domestic socio-political context, but its potential impact on foreign policy is still poorly understood. The current study replicated the putative two-factor model of the construct (Authoritarian Aggression/Submission and Conventionalism) and examined the associations of each factor with perceptions of overall danger to the U.S. posed by other countries and with the support for more militant U.S. foreign policy. As expected, both RWA factors correlated with self-reported levels of political conservatism (r = 0.32, r = 0.33; p < .001) Additionally, Authoritarian Aggression and Submission (but not Conventionalism) were correlated with increased perceived danger from foreign countries (r = .35; p < .001) and increased support for a more militant U.S. foreign policy (r = .25; p < .001). Participants higher in RWA were more likely to view the world as a hostile and threatening place, and in turn support more aggressive military action in response to those fears.


Effects Of Improper Ammunition Storage, Victoria S. Andre Dec 2021

Effects Of Improper Ammunition Storage, Victoria S. Andre

Student Theses

Firearms are commonly used by law enforcement, hunters, and civilians either for protection, sport or criminal activity. Ammunition is used in traditional firearms such as rifles and handguns, and consists of a cartridge case, propellant, a bullet (projectile), and primer. The two types of priming systems within the cartridge that are commonly used today are rimfire and centerfire cartridges. There are several types of malfunctions that can occur with ammunition. Improper ammunition storage is one major factor that plays a role in ammunition failure. One form of improper ammunition storage is where the storage environment being used abruptly changes due …


Investigating Therapeutic Strategies To Target Metabolic Vulnerabilities Of Nsclc Tumors With Mutant Keap1 Gene, Pranavi Koppula Dec 2021

Investigating Therapeutic Strategies To Target Metabolic Vulnerabilities Of Nsclc Tumors With Mutant Keap1 Gene, Pranavi Koppula

Dissertations and Theses (Open Access)

The metabolic vulnerability of cancers has long been envisaged as an attractive window to develop novel therapeutic strategies. Metabolic flexibility at the cellular level encompasses the efficient rerouting of anabolic and catabolic pathways in response to varying environmental stimuli to maintain cellular homeostasis and sustain proliferation. The primary objective of this study is to identify metabolic vulnerabilities bestowed by KEAP1/NRF2 signaling axis through SLC7A11. SLC7A11 is a transcriptional target of NRF2, an essential regulator of cellular anti-oxidant response. Under unstressed basal conditions, NRF2 interacts with KEAP1, a tumor suppressor gene and a substrate adaptor protein of the Cullin3-dependent ubiquitin ligase …


Stat3 Inhibits Type I Interferon Signaling In Type I Conventional Dendritic Cells, Taylor Chrisikos Dec 2021

Stat3 Inhibits Type I Interferon Signaling In Type I Conventional Dendritic Cells, Taylor Chrisikos

Dissertations and Theses (Open Access)

Conventional dendritic cells (cDCs) are an essential immune population, responsible for controlling adaptive immunity and tolerance. Recently, type I cDCs (cDC1s) have been delineated as a distinct cDC subset, uniquely responsible for coordinating T cell-mediated immunity against pathogens and tumors. Although the importance of cDC1s is now well established, the mechanisms that regulate cDC1 function remain largely unknown. Signal Transducer and Activator of Transcription 3 (STAT3) mediates the intracellular signaling of interleukin 10 (IL-10), an immunosuppressive cytokine. Therefore, we hypothesized that STAT3 and IL-10 inhibit cDC1 function and induction of T cell-mediated immunity. Herein, we show that IL-10 inhibits polyinosinic:polycytidylic …


Modulation Of The Receptor Gating Mechanism And Allosteric Communication In Ionotropic Glutamate Receptors, Nabina Paudyal, Nabina Paudyal Dec 2021

Modulation Of The Receptor Gating Mechanism And Allosteric Communication In Ionotropic Glutamate Receptors, Nabina Paudyal, Nabina Paudyal

Dissertations and Theses (Open Access)

Ionotropic glutamate receptors (iGluRs) found in mammalian brain are primarily known to mediate excitatory synaptic transmission crucial for learning and memory formation. The family of iGluRs consists of AMPA receptors, NMDA receptors and kainate receptors with each member having distinct physiological role. In the recent years, significant progress has been made in understanding the biophysical, and functional properties of iGluRs. The development of Cryo-EM and X-Ray crystallography techniques have further facilitated in the structural understanding of these receptors. However, the multidomain nature, large size of the protein, complex gating mechanism and inadequate knowledge regarding the conformational dynamics of the receptors …