Digital Commons Network^™

Visual Prototypes In The Ventral Stream Are Attuned To Complexity And Gaze Behavior, Olivia Rose, James Johnson, Binxu Wang, Carlos R Ponce

Open Access Publications

Early theories of efficient coding suggested the visual system could compress the world by learning to represent features where information was concentrated, such as contours. This view was validated by the discovery that neurons in posterior visual cortex respond to edges and curvature. Still, it remains unclear what other information-rich features are encoded by neurons in more anterior cortical regions (e.g., inferotemporal cortex). Here, we use a generative deep neural network to synthesize images guided by neuronal responses from across the visuocortical hierarchy, using floating microelectrode arrays in areas V1, V4 and inferotemporal cortex of two macaque monkeys. We hypothesize …

Dasatinib And Dexamethasone Followed By Hematopoietic Cell Transplantation For Adults With Ph-Positive All, Matthew J. Wieduwilt, Geoffrey L. Uy, Et Al

Open Access Publications

No abstract provided.

Nrf1 Association With Auts2-Polycomb Mediates Specific Gene Activation In The Brain, Sanxiong Liu, Kimberly A Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K Mcnamara, Wukui Zhao, James M Stafford, Nicolas Descostes, Pedro Lee, Stefano G Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S Papavasiliou, M Scott Perry, Jennifer Humberson, Megan T Cho, Astrid Weber, Andrew Swale, Tudor C Badea, Chai-An Mao, Livia Garavelli, William B Dobyns, Danny Reinberg

Faculty, Staff and Student Publications

The heterogeneous family of complexes comprising Polycomb repressive complex 1 (PRC1) is instrumental for establishing facultative heterochromatin that is repressive to transcription. However, two PRC1 species, ncPRC1.3 and ncPRC1.5, are known to comprise novel components, AUTS2, P300, and CK2, that convert this repressive function to that of transcription activation. Here, we report that individuals harboring mutations in the HX repeat domain of AUTS2 exhibit defects in AUTS2 and P300 interaction as well as a developmental disorder reflective of Rubinstein-Taybi syndrome, which is mainly associated with a heterozygous pathogenic variant in CREBBP/EP300. Moreover, the absence of AUTS2 or mutation in its …

Development Of A Novel Algorithm To Remove Spurious Edges From Biological Networks Through Functional Enrichment, Jeffrey Page

Theses

The field of systems biology has facilitated the modelling of large and complex biological networks. These networks, generated from prior knowledge contained in the corpus of medical and scientific literature, or from experimental data are being used to model differing macromolecule networks associated with distinct disease states. While these networks are vital in understanding disease pathology and possible treatment options, they are rife with spurious interactions. These interactions arise from the methods used to create such networks, where the ability to discriminate between direct and indirect relationships is a challenge. To combat these spurious interactions an algorithm that leverages functional …

November 2021 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.

Faculty Senate Agenda

Faculty Senate Agendas

No abstract provided.

Micronutrient Supplements Can Promote Disruptive Protozoan And Fungal Communities In The Developing Infant Gut, Ana Popovic, Celine Bourdon, Pauline W. Wang, David S. Guttman, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta, Robert H J. Bandsma, John Parkinson, Lisa G. Pell

Centre of Excellence in Women and Child Health

Supplementation with micronutrients, including vitamins, iron and zinc, is a key strategy to alleviate child malnutrition. However, association of gastrointestinal disorders with iron has led to ongoing debate over their administration. To better understand their impact on gut microbiota, we analyse the bacterial, protozoal, fungal and helminth communities of stool samples collected from a subset of 80 children at 12 and 24 months of age, previously enrolled into a large cluster randomized controlled trial of micronutrient supplementation in Pakistan (ClinicalTrials.gov identifier NCT00705445). We show that while bacterial diversity is reduced in supplemented children, vitamins and iron (as well as …

Pelagic Tunicate Grazing On Marine Microbes Revealed By Integrative Approaches, Kelly R. Sutherland, Anne W. Thompson

Biology Faculty Publications and Presentations

Marine microorganisms comprise a large fraction of ocean carbon and are central players in global biogeochemical cycling. Significant gaps remain, however, in our understanding of processes that determine the fate, distribution, and community structure of microbial communities. Protists and viruses are accepted as being part of the microbial loop and a source of microbial mortality. However, pelagic tunicates (salps, doliolods, pyrosomes, and appendicularians), which are abundant in oceanic and coastal environments and consume microorganisms with higher individual grazing rates than other common grazers, remain underappreciated in their role controlling microbial communities, distributions, and flux through ecosystems. In spite of sampling …

Optimization Of Non-Coding Regions For A Non-Modified Mrna Covid-19 Vaccine, Makda S Gebre, Susanne Rauch, Adrianus C M Boon, Et Al

Open Access Publications

The CVnCoV (CureVac) mRNA vaccine for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was recently evaluated in a phase 2b/3 efficacy trial in humans

Genetic Studies Of Metabolic Syndrome In Arab Populations: A Systematic Review And Meta-Analysis, Zahrah Al-Homedi, Nariman Afify, Mashal Memon, Habiba Alsafar, Guan Tay, Herbert F. Jelinek, Mira Mousa, Nadia Abu-Samra, Wael Osman

Research outputs 2014 to 2021

Background:

The metabolic syndrome (MetS) is prevalent in Arabian populations. Several small-scale studies have been performed to investigate the genetic basis of MetS. This systematic review and meta-analysis aimed to examine whether candidate gene polymorphisms are associated with MetS susceptibility among ethnic groups of the Arabian world and to suggest possible directions for future research regarding genetic markers and MetS.

Methods:

A search was conducted for peer-reviewed articles that examined the genetic association of MetS in Arabian populations in the following databases: Medline, Embase, Scopus, Direct Science, Web of Science, ProQuest, and Google Scholar until March 31, 2021. Articles were …

Breeding And Feeding Habitat Selection By An Island Endemic Bird May Increase Its Vulnerability To Climate Change, Paul M. Radley, Eddie J. B. Van Etten, David Blake, Robert A. Davis

Research outputs 2014 to 2021

Characterizing patterns of habitat use is an important first step for effective conservation planning. Species restricted to low-lying islands are at greatest risk from climate change-related sea level rise, and requirements for breeding and foraging habitat may determine their risk from tidal inundation. The endangered Micronesian Scrubfowl (Megapodius laperouse senex) is a model species for understanding these impacts. This species faces the cumulative challenges of tourist visitation, invasive species, and rising sea levels, yet little is understood about its habitat use in the Rock Islands Southern Lagoon Conservation Area (RISL) of Palau. We studied the habitat requirements of this mound-nesting …

Case Report: Pafah1b1 Mutation And Posterior Band Heterotopia With Focal Temporal Lobe Epilepsy Treated By Responsive Neurostimulation, Frank G. Gilliam, Paddy Ssentongo, Michael Sather, Yuka I. Kawasawa

School of Medicine Publications

Subcortical band heterotopia (SBH), also known as double cortex syndrome, is a malformation of cortical development caused by inherited or somatic gene variants. We present a case of a young adult with posterior SBH and electroclinical features of focal neocortical temporal lobe epilepsy. Genomic blood analysis identified a pathogenic somatic mosaicism duplication variant of the PAFAH1B1 gene. Despite bilateral cortical MRI abnormalities, the interictal and ictal EEG findings indicated a focal epileptogenic region in the left posterior temporal region. Chronic responsive cortical neurostimulation across two four-contact depth electrodes placed 5mm on either side of the maximal interictal spiking identified during …

The Contribution Of Racism-Related Stress And Adversity To Disparities In Birth Outcomes: Evidence And Research Recommendations, Sabrina R. Liu, Laura M. Glynn

Psychology Faculty Articles and Research

Currently, racial and ethnic differences in adverse birth outcomes and infant mortality are some of the largest and most persistent health disparities in the United States. This narrative review article synthesizes existing literature to present a conceptual model of how racism-related stress and adversity are critical determinants of such disparities. We describe how historical and ongoing racism has created conditions wherein women of color are disproportionately exposed to chronic, multilayered stress and adversity and how the biological consequences of exposure to these stressors confers risk for adverse birth outcomes. Next, we identify important priorities and considerations for future research, including …

Application Of Artificial Intelligence In Academic Libraries In Nigeria, Augustine Alhaji Adejo Phd, Ali Yakubu Misau

Library Philosophy and Practice (e-journal)

Application of Artificial Intelligence is now evidence in all spheres of life, in the educational, medical, economy sectors likewise in the library to ensure prudence of available resources for better output. This research focused on the application of Artificial intelligence in Academic libraries in Nigeria. The research design adopted was qualitative research method, using expository approach for this study. The research objective set to guide this study is how the application of Artificial Intelligence could be used in Nigerian Academic Libraries. Literatures were reviewed in relation to AI study. Findings from the present study showed that AI could be applied …

The Islamic Creed Is A Rational ‎Belief That Instinctively Leads ‎Humanity And Calls For ‎Psychological Stability, Wijdan Karaki

Jerash for Research and Studies Journal مجلة جرش للبحوث والدراسات

Man had come to the earth as a worshipper and successor to Allah. The faith in Allah and worshipping ‎Him represent a means of spiritual and psychological balance. This research aims at explaining the ‎feeling of human being and faith in Him for the biological viewpoint which represents the instinct ‎based on the concept of the (DNA) which scientists have declared the description of its symbols in the ‎year 2000. In addition to clarification that faith in Allah is a reasonable logic, according to the theory of ‎the Swiss (piaget) concerning cognitive development which explains the development of human ‎thought …

Honors Symposium Fall 2021, Georgia Southern University Honors College

Honors Symposium (2020-2022)

Program for the Fall 2021 Honors Symposium hosted by the Honors College of Georgia Southern University.

The Honors College is an inclusive community of scholars that fosters intellectual and professional development through undergraduate research and creative scholarship, experiential learning, global engagement, and personalized mentorship.

Every honors student, in order to graduate as an honors scholar, must complete an honors thesis or project. Thesis presentations feature graduating seniors who are delivering oral presentations of the results of their honors thesis work. As the titles and abstracts in this program indicate, these projects span the realms of inquiry and creativity available here …

Finding Our Stride – A Health System Repository 4 Years In / “Providence Patents – Using An Institutional Repository To Promote Technology Transfer, Heather J. Martin, Amanda Schwartz

Medical Institutional Repositories in Libraries (MIRL)

In 2018 Providence launched its Digital Commons Institutional Repository (IR) becoming one of only a small group of large health systems providing such a service. In nearing the end of Year 4 there has been sustained growth and continued engagement of this initiative. Expanding on the initial ask from senior leadership to simply track and compile Providence scholarly activity, subsequent years saw significant development in scope and scale of the IR. New projects included the creation of special collections, including: COVID-19 Research; Environmental Stewardship; Genomics; Diversity & Inclusion; and a Patents collection. The library partnered with nursing and graduate medical …

Characteristics And Causal Factors For The Receptive-Expressive Gap In Typically Developed Spanish-English Adult Bilinguals, Rachael Janelle Javaherian

LSU Master's Theses

A receptive-expressive language gap occurs when a standardized receptive score is statistically greater than an expressive score in either a primary or a second language. In bilingual children, gap studies already exist for determining language impairment. In adults, there are few studies; nevertheless, one needs to distinguish between typical language patterns of bilingualism due to non-pathological loss of L1 skills versus problems resulting from accidents, disease, or age. To this end, the present study attempted to expand findings of studies by Gibson et al. (2012 and 2014) that focused on analysis of the gap and possible factors influencing its existence …

Effect Of Concentrate Supplementation On Milk Yield Of Crossbred Holstein X Zebu Cows Grazing Elephantgrass, Fermino Deresz, Antonio Carlos Cóser, Rui Da Silva Verneque

IGC Proceedings (1977-2023)

The study was carried out using 12 ha of Elephantgrass (Pennisetum purpureum Schum.) pasture, fertilized with 660 kg/ha/year of 20.05.20 formula, during the rainy season of 1999. It was used eight cows per treatment/site in a completely randomized block design. Blocks were based on milk yield and date of calving. Pasture was managed with 30 days of resting period using a stocking rate of five cows/ha. The objective of the study was to evaluate the effects of feeding concentrate for the first 60 (T60) or 120 days (T120) post-partum on milk yield, in relation to the control-group (T0), fed …

Supplementation Of Dairy Cows Under Alfalfa Grazing Conditions With Ground Corn, A. R. Castillo, L. A. Romero, O. R. Quaino, E. A. Comeron, M. C. Gaggiotti

IGC Proceedings (1977-2023)

Two trials were carried out during the Autumn of 1991 and 1992 to investigate the effects of corn supplementation on lactational performance of dairy cows under alfalfa grazing. Forty two multiparous Holstein cows with 30-60 days in milk were used in a randomized continuous design with covariance analysis. The treatments were 0.0, 3.5 and 7.0 kg.day^-1 of corn grain supplementation (T1, T2 and T3 respectively) in 1991 and 0.0, 3.0, 6.0 and 9.0 kg.day^-1 (T1, T2, T3 and T4 respectively) in 1992. Six cows per treatment were used divided in 3 cows per grazing paddock. Dry matter (DM) …

Animal Production From Tree-Pasture Association Systems In Brazil, João C. Saibro

IGC Proceedings (1977-2023)

Agroforestry systems (AFS) in general and silvipastoral systems (SPS) in particular, have been studied intensively in Brazil since the 1980’s. The majority of the research work has been conducted in the wet tropical Amazon region, in the semi-arid conditions of the Northeast, and under subtropical soil and climatic conditions in the Southeast or in the South. Research emphasis has been placed on interactions between the main components of AFS: tree, pasture, soil and microclimatic elements. Evaluation of animal performance in SPS generally has not been the main objective of experiments. A recent survey of research on SPS using Eucalyptus spp …

Mediterranizing Gauguin. Giuseppe Biasi’S Africa And Sardinia, Giuliana Altea

Artl@s Bulletin

Looking at the North- African stay of the artist Giuseppe Biasi (1885–1945), the paper deals with a brand of Mediterraneism marked by issues of national and regional identity. A key figure of the regionalist movement in his native Sardinia, in Egypt Biasi sympathized with the painters Mukhtar and Said’s nationalist ideals. Back in Italy, his works showed a conflation of the African and Sardinian worlds, implicitly confirming the theories of the anthropologist Giuseppe Sergi about the Italians as Mediterranean race and contributing to spread the fascist notion of a mediterraneism aimed at justifying colonialism.

Beyond Noucentisme: Joaquim Sunyer’S Mediterranean Pastoral, Maria Lluïsa Faxedas

Artl@s Bulletin

Taking as case study the painting Pastoral (1910–11), one of the iconic works of the Catalan artist Joaquim Sunyer (1874–1956), this paper examines the established link between Mediterraneanism and Noucentisme in Catalan culture in the first decades of the twentieth century. A look at how this work was received when it was first exhibited, and the sub-sequent re- reading of its iconography, enables us to understand Pastoral nowadays not as much as a symbol of Noucentisme, but more as a potential meeting point between the different aesthetic trends of the period.

“Dusty” Arcadias: Pastoral Visions And Greek Landscape In The Work Of Fred Boissonnas In The Context Of Mediterranean Cultural Myth, Marianna Karali

Artl@s Bulletin

In the following paper, I examine the possible affiliation the Swiss commercial photographer Fred Boissonnas shared with certain groups of Greek-French Nationalists as early as in 1903-1907 and the way this particular nexus inspired the integrity of his work on Greek landscape, forming as well his naturalistic vision on photography. Within the visionary spectrum of a northerner excursionist and the aesthetic eye of a Pictorialist photographer, Boissonnas marked an Innovative gaze upon Mediterranean Arcadian Imagery, altering the Symbolic Classicism of von Gloeden paradigm of Italian South.

Gray's Mill: Fish America Application Requesting Funding For Gray's Mill Pond Habitat Improvement, 2005

Documentation

An application to Fish America requesting $23,500 in funds for Gray's Mill habitat restoration by increasing the overall area of deep water habitat by "dredging those portions of the pond where sediment has collected." Detailed information on the Project's description and need, activities, objectives, timeline, environmental concerns, and budget. Application submitted in anticipation of work to be done in 2005.

The State Of Animal- Assisted Interventions In France: Is The Iahaio Model Relevant?, Alice Mignot, Gérard Leboucher, Véronique Servais, Karelle De Luca

People and Animals: The International Journal of Research and Practice

Animal- assisted interventions (AAI) became more generalized in health care settings and their development in Europe is increasing. In France, the practice has grown in the absence of official recognition and regulation. In this context, we aim to identify the main characteristics of the French practice of AAI that can influence the establishment of a local regulation. Second, we aim to question the relevance of the model proposed by the International Association of Human- Animal Interaction Organizations (IAHAIO) distinguishing animal- assisted therapies (AAT) and (AAA) animal- assisted activities from the French practice of AAI. We interviewed 111 French handlers in …

Physiological Responses To Water Deficit By Sorghum Bicolor Genotypes Varying In Expression Of The Limited Transpiration Trait, Marylou C. Machingura

Georgia Journal of Science

The ability by land plants to partially close their stomata in response to high vapor pressure deficit, called the limited transpiration trait, is a rare phenomenon in crop plants. The characteristic has been demonstrated in several crop species including Sorghum bicolor. The molecular and physiological basis for the limited transpiration trait is however, not clear. This study was conducted to determine the physiological attributes associated with the limited transpiration trait in three sorghum genotypes SC1345, SC35 and Macia. Plants of these three sorghum genotypes were established in a greenhouse and subjected to water deficit stress. Chlorophyll fluorescence and relative …

Effect Of Estrogen Pretreatment On Glial-Like Cell Viability Following Stress Response Hormone Treatment, Bridget N. Smith, Kevin S. Burgess, Kathleen S. Hughes

Georgia Journal of Science

The role of steroid hormones is critical in cellular function. Previous studies have found a positive correlation between the endogenous estrogen 17β-estradiol and cellular protection. Conversely, exogenous conjugated equine estrogens provide less protective mechanisms than endogenous hormones, and little is known about the role of estrogens in cellular protection during a stress response. In the present study, we compare the effects of short-term estrogen pretreatments (alone and in combination) on cell viability when cells with glial cell morphology are exposed to either epinephrine or cortisol. Results showed that 1 µM 17β-estradiol resulted in decreased cell viability following the epinephrine treatment; …

Comparing Allelochemicals Of ​English Ivy And Native Georgia Plants​, Rebecca Senft

Symposium of Student Scholars

English Ivy (Hedera helix L.) is a common invasive plant causing biodiversity losses across the southeast and parts of the northwestern US. The mechanisms by which Ivy invades native ecosystems are not well understood but may include allelopathy, a process through which one species produces biochemicals that disrupt competitors. These biochemicals are often produced and exuded by roots into soil, making them difficult to isolate. This study used a soil-less hydroponic system and gas-chromatography mass spectroscopy to examine differences in the chemicals produced by roots of native Georgia plants and English Ivy. Our results suggest there are differences in the …

Snake Venom Peptides And Toxin Targeting The Main Protease Of Sars-Cov-2, Breauna Strawder, James Stewart, Mohammad A. Halim

Symposium of Student Scholars

The corona virus began to spread in Wuhan, China which caused it to spread worldwide creating a global pandemic in the beginning of 2020, infecting over 243 million and killing over 4.5 million people worldwide. Significant efforts were made to produce vaccines against the virus, which led the recognition of a few vaccines that has been approved by FDA. These vaccines, Pfizer-BioNTech, Moderna and Johnson & Johnson, which all have efficacy against Covid-19. Despite having vaccines, COVID-19 is still present and infecting millions and killing thousands of people every day. Multiple therapeutic options would allow us to slow down or …