Digital Commons Network^™

Pipeline Corrosion And Relevant Microbial Influence, Renee E. Bamberger

Williams Honors College, Honors Research Projects

This study investigated the role of microbial activity and oxygen availability in the corrosion of carbon steel pipelines with a focus on microbially influenced corrosion (MIC). Sediment collected from Old Woman Creek, Ohio, was used to simulate natural soil conditions, and carbon steel coupons were incubated under four treatments: nonsterile oxic, nonsterile anoxic, autoclaved oxic, and autoclaved anoxic over 85 days. Corrosion was assessed through mass loss measurements and the analysis of pH, sulfate, chloride, and dissolved iron concentrations. The greatest mass loss was observed in autoclaved oxic conditions, contrary to the initial hypothesis that microbial activity would greatly enhance …

Reconnecting The Body With Nature: Inspired By Advances In Biomimicry, Elyse M. Orosa

Williams Honors College, Honors Research Projects

Reconnecting the Body with Nature: Inspired by Advances in Biomimicry will visually address the symbiotic relationship between nature and humans. The drawing series is inspired by the growing design field of biomimicry and its technological and architectural innovations influenced by nature’s systems and physical adaptations. Just as nature is limited by human misuse, humans are physically and neurologically limited by the state of the environment, and with this, form and function of both nature and humans will be equally represented and explored throughout the body of work presented. Biomimicry can help solve environmental issues such as rising CO2 emissions and …

The Connection Between Medicaid And Obesity In Northeast Ohio, Sophie Kheder, Emmie Kelley

Williams Honors College, Honors Research Projects

Obesity is a major public health concern in the United States that is projected to increase exponentially over the next few years. Obesity is commonly associated with a lower socioeconomic status. Lower-income individuals tend to be supported by Medicaid, a federal insurance program for low-income Americans. Prior studies have shown a positive correlation between income status and obesity prevalence. Our goal was to find if there was a correlation between Medicaid patients and obesity in Northeast Ohio, to provide physicians with a set of characteristics to better combat obesity, since preventative and treatment guidelines are tailored to national trends. We …

Morphological Variation Of The Clavicular Rhomboid Fossa: Bilateral Asymmetry, Sexual Dimorphism, And Environmental Influences, Michaela Tucker, Skylar Hall

Williams Honors College, Honors Research Projects

Morphological variation on the clavicle, specifically the rhomboid fossa, may be impacted by age, sex, laterality, and mechanical stress. Occupational stress and loading conditions lead to bone remodeling and adaptation to change, altering the costoclavicular ligament site. A sample of 94 bilateral clavicles from individuals ages 16-40 years was analyzed using computer tomography (CT) and 3-dimensional reconstruction. Clavicles were categorized into five groups: flat, smooth, elevated, depressed, and pitted. Chi-squared analyses were used to test associations between morphology and age, side, and history of strenuous lifting. Significant differences were observed between class and sex for the leftsided clavicle group. Female …

An Exploration Of The Status And Legacy Of The Latin Language, Jean M. Allison

Williams Honors College, Honors Research Projects

The Latin language, widely referred to as a "dead language," has historically held a great influence throughout various cultures and dialects, still holding some of this importance in the contemporary world. This project intends to explore these influences, both modern and historical, as well as how the language is now considered dead. A variety of written material spanning several centuries will be utilized to examine these aspects of the project posed within the presented overarching theme. All of the relevant information from these texts will ultimately be summarized and critically detailed within a written report that displays the findings of …

Effects Of Warmer Springs And Urbanization On The Nest Choice Of Temnothorax Ants, Keana Royce

Williams Honors College, Honors Research Projects

Climate change is altering winter and spring conditions in northeast Ohio, with urbanization and the urban heat island effect likely intensifying these changes. This preliminary study examined how Temnothorax ants alter nest-site preference in response to climate change and urbanization. I hypothesized that colonies exposed to warmed treatments would select hickory nuts to buffer against thermal/urban stressors. Identical in situ experimental setups were deployed at a rural site and an urban site and data collection occurred from late winter to early spring. Control colonies experienced ambient temperatures while experimental colonies were warmed +4°C above ambient temperatures. Colonies had the choice …

C. Difficile Detection Method For First Responder Glove Application, Alli N. Senedak

Williams Honors College, Honors Research Projects

Clostridioides Difficile (C. diff) is a Anaerobic Gram-positive bacillus that is capable of spore formation, making it difficult to control its spread and duration in clinical environments. This phenomenon can provide danger to first responders, healthcare workers, and patients. The goal of this project is to create a biosensor capable of detecting C. diff in a clinical setting that can be applied to a glove apparatus. The project will involve the use of C. diff aptamers activated on the surface of an electrode. Once surface activation has been verified via surface analysis, the electrodes will be exposed to C. diff …

Luckett Davis Lecture Notes Collection - Accession 1846, Luckett Vanderford Davis

Manuscript Collection

The Dr. Luckett Davis Lecture Notes Collection documents the teaching and academic work of Luckett Vanderford Davis, Professor of Biology at Winthrop University, where he served from 1964 until his retirement and later held the title of Emeritus Professor of Biology. The collection consists primarily of lecture notes, seminar materials, laboratory manuals, and instructional aids used by Dr. Davis in teaching a wide range of undergraduate biology courses.

The bulk of the collection contains handwritten and typed lecture notes prepared for courses in zoology, genetics, evolution, ecology, and marine biology. These materials document Dr. Davis’s approach to teaching biological sciences …

Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu

Honors Undergraduate Theses

Oral hormonal contraceptives (OHCs) are widely used among reproductive-age women; however, their gastrointestinal (GI) side effects remain understudied. The present study examined associations between OHC use, GI, physical, and psychological symptom burden in a large sample of undergraduate women. Participants (N = 669) aged 18 to 25 years were recruited from UCF’s SONA system and classified into three groups based on self-reported contraceptive status: no birth control, combined estrogen–progestin OHC, and progestin-only OHC. Participants completed GI questionnaires, as well as physical and mental health symptoms ones.

Multivariate analyses indicated that overall GI symptom profiles did not differ significantly by birth …

Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik

Honors Undergraduate Theses

Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …

Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici

Honors Undergraduate Theses

Manuka honey is known for its vital usage in wound healing, being an agonist towards fighting infections, and is an acting antioxidant [32]. Its main constituents are flavonoids and phenolic compounds, with methyl syringate (MSYR) being a major active ingredient. The specific compounds responsible for these antioxidant effects, particularly in the CNS, remain unclear. It is hypothesized that pre-treatment of mouse neuroblastoma cells with MSYR followed by hydrogen peroxide exposure will activate the AMPK/SIRT1/PGC-1a pathway, due to MSYR’s phenolic structure, and thus reduce oxidative stress and improve mitochondrial biogenesis. Hydrogen peroxide is a standard reactive oxygen species (ROS) treatment to …

Transforming Florida Chemistry Education: Exploring Information Literacy Strategies From Singapore, Han N. Le

Honors Undergraduate Theses

This study explores the applicability of Singapore’s information literacy (IL) strategies within Central Floridian higher education environments. Singapore’s national IL framework, supported by its Ministry of Education, integrates information and communication technology (ICT), professional development, and lifelong learning initiatives through a standardized, systemwide approach. In contrast, IL instruction in the United States is largely decentralized, often limited to one-time sessions or elective courses. To investigate the feasibility of adapting Singapore’s practices, surveys were distributed to faculty and librarians across Florida’s twelve public universities, yielding responses that highlighted varying levels of IL integration, limited institutional support, and minimal professional training related …

Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke

Honors Undergraduate Theses

Insertions and deletions (indels) in DNA sequences of genes are linked with cancers such as glioblastoma (GB). Thus, indels may be used as potential cancer biomarkers. In the NANOG gene, its pseudogene NANOGP8 has a 22 base pair insertion sequence for GB patients. In this work, the NANOG gene and the insertion sequence were detected in one sample using a dual-fluorescent assay containing two multicomponent split deoxyribozyme (Dz) probe complexes. One complex used TXR fluorescence to detect the gene regardless of the insertion’s presence. The other complex used fluorescein (FAM) fluorophore to detect the insertion. The probes were able to …

Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright

Honors Undergraduate Theses

This research draws on feminist theory and monster theory to perform a close rhetorical analysis of incidents in the television show Buffy the Vampire Slayer (Buffy) where female characters are violated physically, psychologically, and/or sexually. Buffy is one of the most-analyzed television shows of all time, with a particular emphasis on the show’s engagement with feminism; however, the issue of violation has received little scholarly investigation despite multiple instances of it within the show. Through examining the rhetorical elements (such as dialogue, camerawork, body language, and character response) that surround incidents of violation, this research reveals that Buffy …

Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell

Honors Undergraduate Theses

From the fourteenth to the eighteenth centuries, European anatomical illustration underwent major transformations in response to changing scientific methods, technologies, and visual conventions, reflecting critical transitions in anatomical history. Scientific evolution allowed these images to achieve increasing structural precision and internal detail, though they frequently diverged from anatomical forms as they are understood today. This study examines how anatomical inaccuracies across five centuries emerged not from ignorance, but from deliberate mediation between purpose, observation, pedagogy, artistic convention, and cultural ideology. Through close analysis of works in visual comparison to their modern counterparts, this thesis identifies specific deviations from the twenty-first …

Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas

Honors Undergraduate Theses

Background: South Asian Americans experience disproportionately high rates of cardiovascular disease, yet the social determinants contributing to these disparities remain understudied.

Objective: This systematic review examines the role of social determinants of health (SDOH) in shaping cardiovascular outcomes among South Asian Americans.

Methods: A systematic literature search was conducted across PubMed, MEDLINE, and Web of Science using predefined search terms related to South Asian populations, cardiovascular health, and SDOH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines, and study screening and management were performed using Covidence. A total …

The Development And Implementation Of A Computational Framework To Simulate Patellofemoral Joint Mechanics, Mahmood Rashedi

Master’s Theses

Anterior knee pain affects approximately 25% of adults and is associated with altered joint mechanics. Patellofemoral joint (PFJ) models vary widely in complexity, with no established gold standard. Musculoskeletal models efficiently estimate joint loading but do not capture tissue-level mechanics, whereas finite element (FE) models provide tissue-level predictions at greater computational cost. This thesis developed a workflow to evaluate relationships between musculoskeletal model-predicted PFJ loads and FE-predicted cartilage mechanics, examined the impact of altered quadriceps activation, and introduced improved computational models.

Marker trajectories and ground reaction forces were collected from four adults (2 male, 2 female) during walking and squatting. …

Trends In Pharmaceutical Patent Settlements Since Actavis And Private Plaintiffs' Causation Requirement, Kelly Lear Nordby

Minnesota Journal of Law, Science & Technology

In January 2025, the U.S. Federal Trade Commission (FTC) reported that a new form of “possible compensation” from brand drug manufacturers to generic (or biosimilar) manufacturers, specifically “quantity restrictions,” have become “increasingly prevalent” in pharmaceutical patent settlement agreements filed with FTC under the Medicare Prescription Drug, Improvement, and Modernization Act of 2003. As the FTC noted, “quantity restrictions” may reduce the settling firm’s incentives to compete, resulting in supracompetitive prices for the brand and generic drug. This article summarizes trends in pharmaceutical patent settlement agreements and reverse-payment antitrust litigation since the Supreme Court’s landmark decision in FTC v. Actavis. Focusing …

Exploring The Role Of Dialogue In Student Development And Knowledge Generation, Alison Warren

Indiana STEM Education Conference

In classrooms where students are given the space to engage in dialogue, ask questions, and negotiate ideas, science learning comes to life. Providing opportunities for students to negotiate ideas publicly, through dialogue, then privately, through writing has the potential to maximize student idea generation. Although dialogue is widely recognized as important for engagement and communicating ideas, it has also been framed as an epistemic tool. However, the role of dialogue as a sense-making process or epistemic tool, and its relationship to other forms of language, remains under-explored. This study addresses this gap by investigating the role of dialogue and how …

Intergenerational Bible Study As A Means Of Discipleship At The Waukesha Community Seventh-Day Adventist Church, Myoung Kwon

Doctor of Ministry Projects

Problem

The Waukesha Community Seventh-day Adventist Church faced a plateau in Bible study engagement. Newly baptized members were disengaging from continuing Bible study and not reproducing disciples, resulting in a spiritual growth process that was minimal and heavily dependent on the pastor.

Method

The DMin student chose action research as a method for developing, implementing, and evaluating an intergenerational Bible study strategy to revitalize discipleship. The three-phase intervention included: (1) a sermon series featuring intergenerational activities to recruit participants; (2) a workshop to equip lay members as Bible study teachers; and (3) an eight-week program with two tracks: a one-on-one …

Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous

Honors Undergraduate Theses

Cellular senescence is a biological process in which damaged cells exit the cell cycle while remaining metabolically active and accumulating within tissues. Senescence plays a complex role in breast cancer progression, largely through the secretion of senescence-associated secretory phenotype (SASP) factors. These factors include a broad range of inflammatory cytokines, chemokines, and signaling molecules that can influence the tumor microenvironment.

Studies suggest that senescence may significantly promote cancer metastasis. Therefore, this study aims to investigate the genes involved in cancer progression and to improve understanding of how SASP is regulated, which is critical for improving breast cancer outcomes. The central …

Evaluation Of Tactile Cueing Embedded In An Aviation Headset On Pilot Altitude Control, Nicholas D. Wilson, Jessica Van Bree, Matthew Cleveland, Sunny Charakuru, Thomas Petros, Richard Ferraro, Kouhyar Tavakolian

Journal of Aviation/Aerospace Education & Research

This study evaluated the effectiveness of tactile cueing integrated into a pilot’s headset on pilot altitude control during simulated instrument conditions. Pilots typically rely on visual and auditory inputs to maintain situational awareness, but in high-workload or instrument meteorological conditions (IMC), these channels can become overloaded. One underutilized alternative for alerting is a tactile cueing apparatus. Using an X-Plane simulation of a Piper Archer equipped with a G-1000 avionics suite, 39 FAA-certified pilots flew two precision approaches. The experimental group (n = 20) received haptic cues via ear seal-embedded tactors when deviating from assigned altitude or glideslope. The control group …

Feasibility Of Telehealth-Delivered Gut-Directed Hypnotherapy For Managing Gastrointestinal Health: Exploring Specific Vs. Nonspecific Effects, Sabrina Romero

Honors Undergraduate Theses

This randomized controlled trial evaluated the feasibility and efficacy of telehealth-delivered Gut-Directed Hypnotherapy (GDH) compared to General Hypnotherapy (GH) for managing gastrointestinal symptoms associated with disorders of gut–brain interaction (DGBI). Eleven adults were randomized to receive four 1-hour hypnotherapy sessions over a 14-day period via Zoom (GH n = 5; GDH n = 6). Primary outcomes included PROMIS GI Belly Pain T-scores and Abdominal Pain Ratings assessed at baseline and post-treatment. Follow-up assessments were conducted at three months (n = 8). At post-treatment, participants receiving GDH demonstrated significantly lower PROMIS GI Belly Pain T-scores compared to GH, F(1, …

Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh

Honors Undergraduate Theses

Gastroesophageal Reflux Disease (GERD) can progress to the precancerous Barrett’s Esophagus (BE) condition, in which the normal esophageal squamous epithelium is replaced with a columnar epithelium containing goblet cells. Mucins, sticky substances, are secreted in response to bile acid exposure during reflux episodes to protect the esophageal epithelium. Goblet cells secrete these mucins, which can also scaffold microbial colonization. Probiotic Lactobacillus bacteria can use glycosidase enzymes to process mucin and metabolize them into their component sugars (glycans). This project aims to identify the role of the Lactobacillus-mucin interaction in BE, as glycan availability could confer an advantage to Lactobacillus …

Embryonic Option-Hood, Elissa Philip Gentry, Mackenzi Barrett, W. Kip Viscusi

SMU Law Review

A frozen embryo represents not merely a potential human life but a deferred decision to trigger this potential. Parties value this opportunity for deferral because it allows them to retain the option to attempt conception after any uncertainty about future events or desires has resolved. Failing to recognize this “option value” of embryos has resulted in confusion over the best approach to allocating ownership of embryos and calculating damages for reproductive harms. This Article provides a novel paradigm showing that embryos should be treated as neither persons nor mere property; instead, a significant portion of their value is in their …

Racing To Safety: Tax Policy For Ai Safety-By-Design, Mirit Eyal-Cohen, Yonathan Arbel

SMU Law Review

The White House recently announced its vision of artificial intelligence (AI) policy: AI development is a race and America must win it. To that end, a new America’s AI Action Plan directs federal agencies and states to remove regulatory barriers to AI development and accelerate innovation. This approach leaves limited room for regulatory measures that would address the safety risks of powerful AI systems: their behavior in novel domains remains unpredictable, their decision-making opaqueness, and their alignment with human values is uncertain. While experts warn of large-scale accidents, policymakers find themselves in a bind: Regulate AI and cede ground to …

The Futility Of “Genocide” In Ending A Genocide, Shannon Fyfe

Scholarly Articles

After the horrors of World War II, the Genocide Convention of 1948 sought to invest the international community in creating legal obligations that “sovereign” states commit to preventing and punishing future genocides. Unfortunately, this has not succeeded. International legal jurisprudence pertaining to identifying and punishing genocide has developed at the International Court of Justice and at other international criminal courts and tribunals. Yet the invocation of the term “genocide” in public, academic, or legal discourse has generally failed to ensure the participation of the international community in stopping a genocide. The United States, for instance, has failed to play the …

Navigating The Double Helix: Patent Law, Bioethics, And The Regulatory Future Of Gene Editing, Kayla Flanders

Cardozo Arts & Entertainment Law Journal

No abstract provided.

The Ocean Is Not A Machine: A Feminist Media Analysis Of Oceanographic Models, Simulations, And Futures, Clarissa Chevalier

Study of Women, Gender, & Sexuality: Faculty Publications

This article examines how scientific and artistic representations and technologies shape ocean futures. Dominant Western oceanography frequently engages mechanistic metaphors that conceptualize the ocean as a machine, pump, or carbon sponge. This way of visualizing the ocean, guided by the logics of control and quantification, shapes contemporary remote sensing, modeling, and prediction technologies. Alternative approaches to oceanographic representation, including Indigenous, anticolonial, Black feminist, and artistic approaches, offer critical counterweights to destabilize the authority granted to mechanistic oceanographic representations. Ocean simulations and scale models are infrastructures through which ocean futures are rendered and presented in multidimensional space. Through a comparative media …

Decoding A Decade: Evolution In Distal Radius Fracture Techniques From Past To Present, Embracing The Efcr Method, Natasha G. Dark, Ahmed S. Raihane, Laurie G. Wells, Deana Mercer

Western Journal of Orthopaedics

No abstract provided.