Digital Commons Network^™

Possibilities In Simulated Reality, Yuan Yuan

Theses

This thesis work is based on two simple questions- what is reality, and is there any way to determine if you live in a real world. Whether from ancient times or the present, the east or the west, or fiction movies to philosophical reflection, countless people have ruminated on these questions. The answer seems obvious that reality is anything we can perceive based on our perceptions, but it’s not necessarily factual even though it feels very real. A philosophical viewpoint called epistemological skepticism indicates that we cannot be certain of anything, and there is a philosophy hypothesis named simulation theory …

How Do Genetic Relatedness And Spatial Proximity Shape African Swine Fever Infections In Wild Boar?, Tomasz Podgórski, Kim M. Pepin, Anna Radko, Angelika Podbielska, Magdalena Łyjak, Grzegorz Woźniakowski, Tomasz Borowik

United States Department of Agriculture Wildlife Services: Staff Publications

The importance of social and spatial structuring of wildlife populations for disease spread, though widely recognized, is still poorly understood in many host-pathogen systems. In particular, system-specific kin relationships among hosts can create contact heterogeneities and differential disease transmission rates. Here, we investigate how distance-dependent infection risk is influenced by genetic relatedness in a novel host-pathogen system: wild boar (Sus scrofa) and African swine fever (ASF).We hypothesized that infection risk would correlate positively with proximity and relatedness to ASF-infected individuals but expected those relationships to weaken with the distance between individuals due to decay in contact rates and …

Genotoxicity Evaluation Of Medical Devices: A Regulatory Perspective, Awadhesh N. Jha, Tirukalikundram S. Kumaravel, Tiruvathipuram N. Sathya, Ramalingam Balaje, Pitchaipillai Pradeepa, Desikan Yogaraj, Malliga R. Murali, K. R. Navaneethakrishnan, Sivasubramanian Murugan

School of Biological and Marine Sciences

This review critically evaluates our current regulatory understanding of genotoxicity testing and risk assessment of medical devices. Genotoxicity risk assessment of these devices begins with the evaluation of materials of construction, manufacturing additives and all residual materials for potential to induce DNA damage. This is followed by extractable and/or leachable (E&L) studies to understand the worst case and/or clinical exposures, coupled with risk assessment of extractables or leachables. The TTC (Threshold of Toxicological Concern) approach is used to define acceptable levels of genotoxic chemicals, when identified. Where appropriate, in silico predictions may be used to evaluate the genotoxic potentials of …

The Role Of Decorin And Biglycan Signaling In Tumorigenesis, Valentina Diehl, Lisa Sophie Huber, Jonel Trebicka, Malgorzata Wygrecka, Renato V. Iozzo, Liliana Schaefer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The complex and adaptive nature of malignant neoplasm constitute a major challenge for the development of effective anti-oncogenic therapies. Emerging evidence has uncovered the pivotal functions exerted by the small leucine-rich proteoglycans, decorin and biglycan, in affecting tumor growth and progression. In their soluble forms, decorin and biglycan act as powerful signaling molecules. By receptor-mediated signal transduction, both proteoglycans modulate key processes vital for tumor initiation and progression, such as autophagy, inflammation, cell-cycle, apoptosis, and angiogenesis. Despite of their structural homology, these two proteoglycans interact with distinct cell surface receptors and thus modulate distinct signaling pathways that ultimately affect cancer …

Active And Covert Infections Of Cricket Iridovirus And Acheta Domesticus Densovirus In Reared Gryllodes Sigillatus Crickets, Scott K. Sakaluk, Kristin Duffield, John Hunt, Ben M. Sadd, Brenda Oppert, José L. Ramirez, Karyna Rosario, Robert W. Behle

Faculty Publications – Biological Sciences

Interest in developing food, feed, and other useful products from farmed insects has gained remarkable momentum in the past decade. Crickets are an especially popular group of farmed insects due to their nutritional quality, ease of rearing, and utility. However, production of crickets as an emerging commodity has been severely impacted by entomopathogenic infections, about which we know little. Here, we identified and characterized an unknown entomopathogen causing mass mortality in a lab-reared population of Gryllodes sigillatus crickets, a species used as an alternative to the popular Acheta domesticus due to its claimed tolerance to prevalent entomopathogenic viruses. Microdissection of …

Seeding Rate Effects On Forage Mass And Vegetation Dynamics Of Cool-Season Grass Sod Interseeded With Sorghum-Sudangrass, John A. Guretzky, D. D. Redfearn

Department of Agronomy and Horticulture: Faculty Publications

Interseeding annual warm-season grasses into perennial cool-season grasses has the potential to increase summer forage mass and nutritive value. Knowledge of how seeding rate affects annual warm-season grass establishment, forage mass, and vegetation dynamics remains limited. From 2016–2017, we conducted a field experiment evaluating the effects of seeding rates on sorghum-sudangrass (Sorghum bicolor x S. bicolor var. sudanense) density and forage mass and on the frequency of occurrence of plant species in cool-season grass sod in Lincoln, NE. The experiment had a completely randomized design consisting of six replicates of four seeding rates [0, 14, 28, and 35 …

Celebrating Faculty Excellence, Keith Testa

UNH Today Archive

No abstract provided.

World-Changing, Ali Goldstein

UNH Today Archive

No abstract provided.

State V. Krueger Respondent's Brief Dckt. 48175

Not Reported

No abstract provided.

Performance Of A Validated Spontaneous Preterm Delivery Predictor In South Asian And Sub-Saharan African Women: A Nested Case Control Study, Rasheda Khanam, Tracy C. Fleischer, Nansi Boghossian, Imran Nisar, Usha Dhingra, Sayedur Rahman, Angela C. Fox, Muhammad Iiyas, Arup Dutta, Nurun Naher, Ashoka D. Polpitiya, Usma Mehmood, Saikat Deb, Aziz Ahmed Choudhury, Md Bahadur Badsha, Karim Muhammad, Said Mohammed Ali, Salahuddin Ahmed, Durlin E. Hickok, Najeeha Iqbal, Et. Al.

Faculty Publications

Objectives

To address the disproportionate burden of preterm birth (PTB) in low- and middle-income countries, this study aimed to (1) verify the performance of the United States-validated spontaneous PTB (sPTB) predictor, comprised of the IBP4/SHBG protein ratio, in subjects from Bangladesh, Pakistan and Tanzania enrolled in the Alliance for Maternal and Newborn Health Improvement (AMANHI) biorepository study, and (2) discover biomarkers that improve performance of IBP4/SHBG in the AMANHI cohort.

Study design

The performance of the IBP4/SHBG biomarker was first evaluated in a nested case control validation study, then utilized in a follow-on discovery study performed on the same samples. …

Addressing The Role Of Climate Change In Agriculture And Mexico-Us Immigration, Xiaoxin Liang

Binghamton University Undergraduate Journal

Among the greatest threats of climate change is the significant impact on mass displacement, particularly as it relates to Mexico-US immigration. Low crop yields from worsening climate conditions have been linked to increased migration of Mexican farmers. With a projected 4.2 million additional migrants in the foreseeable future, it poses a contemporary environmental, social, and political dilemma. This policy brief analyzes several provision proposals to be adopted into the United States-Mexico-Canada Agreement (USMCA), as evaluated under economic cost, equity, environmental impact, and feasibility criteria. My research concludes that the most effective and direct provision proposal is the implementation of adaptive …

Outer Surface Protein C Typing Of Borrelia Burgdorferi In The Tick Populations Of The Upper Susquehanna River Basin, New York, Neha Shaikh, Emilie Ernst, Ariel S. Makower, Christine M. Hurley, Ralph M. Garruto, Michel Shamoon-Pour

Binghamton University Undergraduate Journal

Lyme disease, the most common zoonotic disease in the United States, is caused by the spirochete Borrelia burgdorferi. In order to manage and confront the notable rise in Lyme disease cases, it is crucial to cultivate a deeper understanding of B. burgdorferi and its genes. The outer surface protein C (ospC) gene is highly polymorphic and commonly used as a genetic marker due to its crucial role in establishing mammalian infection. We report novel data on the prevalence of B. burgdorferi ospC genotypes in the infected tick populations of the Upper Susquehanna River Basin of New York …

States, Preemption, And Patented Drug Prices, Rebecca E. Wolitz

Seton Hall Law Review

No abstract provided.

Teach And Question Data, Rachel Tomco Novak

ScholarsArchive Data

Data collected from a Teach-and-Question assignment in 11 sections of an introductory science course, during Winter semester 2021.

Digital Markers Of Autism, Ivonne Monarca, Franceli L. Cibrian, Monica Tentori

Engineering Faculty Articles and Research

Autism Spectrum Disorder (ASD) is a neurological condition that affects how a people communicate and interact with others. The use of screening tools during childhood is very important to detect those children who need to be referred for a diagnosis of ASD. However, most screening tools are based on parents' responses so the result can be subjective. In addition, most screening tools focus on social and communicative skills leaving aside sensory features, which have shown to have the potential to be ASD markers. Tactile processing has been little explored due to lack of tools to asses it, however with the …

A Seventeenth-Century Air History In Conversation With Antony And Cleopatra, Laura S. Deluca

Binghamton University Undergraduate Journal

This article works to unpack the recurrences of air-related language utilized in Shakespeare’s Antony and Cleopatra. Throughout this play, the notions of breath, wind, air, and vapor are consistently referenced, demonstrating the way in which atmospheric intangibility was a key point of exploration for contemporary scientists and philosophers. Through this analysis, it is clear that Shakespeare employs breath in three ways: the breath of (public) life, a lack of breath, and, most importantly, breath as a symbol of power and autonomy, which at times overlaps with the breath of life in ways that demonstrate contemporary conceptualizations of living beings. The …

Demigods And Gender Roles: Non-Heteronormative Gender Expressions And The Works Of Rick Riordan, Lee M. Witkowski

Binghamton University Undergraduate Journal

Gender serves as a powerful ideology to systematically oppress minorities, such as women and people within the LGBTQ+ community. This ideology is learned at a young age through media such as fantasy literature. By analyzing several fantasy texts through a lens of gender politics, I track the history of gender in the fantasy genre and posit that inclusive works such as those of Rick Riordan influence children and adolescents to become more accepting of sexual and gender minorities.

Managing Editor's Note, Vanessa Jaeger

Binghamton University Undergraduate Journal

A note from the managing editor about BUUJ 7.1

Elite Women As Tools Of Power In First-Century C.E. Rome, Catherine Manolian

Binghamton University Undergraduate Journal

For the patrician class, marriage was a form of power intended to uphold Roman patriarchy by providing opportunity for social, political, and economic advancement. However, history has shown that the power of marriage also extended to the women involved in these couplings as well. Through marriage, elite Roman women had the power to perpetuate or decimate Rome’s social order. Thus, gender norms were created and enforced in order to maintain patriarchy. Women who did not live up to the social expectations set by these norms were met with opposition. By examining Roman poetry and literature, Roman politics, and profiling the …

Parallel Pandemics: The American Problem Of Anti-Enforcement, Rational Distrust, And Covid-19, Najarian Peters

Seton Hall Law Review

No abstract provided.

Kemampuan Literasi Sains Siswa Sma Topik Usaha Dan Energi, Sigit Triwibowo, Parno Parno, Eny Latifah

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Scientific literacy is an important skill needed in the 21st century. Scientific literacy is encouraged by many countries to deal with economic and technological developments. Scientific literacy is the someones’ capability when solve a problem using the knowledge and scientific thinking. The purpose of this study is to explain student’s scientific literacy on work and energy. The research was conducted on 72 students in class XI MIPA at SMAN 4 MADIUN for the 2020/2021 academic year. The method of data collection was a test. The form of scientific literacy question was essays with a reliability of 0.608. The result of …

The Influence Of Contextual Teaching And Learning (Ctl) Learning Model On 21st Century Skills Of Students In Class X Biology Learning, Enicgia Shantia, Lufri Lufri

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

The low 21st century skills of students in learning biology, because the learning process is still teacher-centered, teachers are still dominant in applying conventional learning. Efforts that can be made to overcome these problems are by applying the Contextual Teaching and Learning (CTL) model. The purpose of this study was to see the effect of the CTL model on the 21st Century skills of students. This research is quasi-experimental research. The population of this study were students of class X SMAN 12 Kerinci. Hypothesis test data analysis was carried out using the t-test. The results showed that the value of …

Bahan Ajar Ipa Berbasis Stem Dalam Menciptakan Paikem Untuk Meningkatkan Kemampuan Berpikir Kreatif Siswa Kelas Iv Pada Tema 2 Selalu Berhemat Energi Sub Tema 1 Sumber Energi, Haerul Salam, Parno Parno, Mohammad Zainuddin

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

The purpose of this research and development is to produce STEM-based science teaching materials in creating PAIKEM to improve students' creative thinking skills in Theme 2 Sub-theme 1 Energy Sources. The method used in developing the product uses the ADDIE model. The results of product development research get a score of 86.38% in the very valid/feasible category to use. The results of product attractiveness get a score percentage of 98.21%. The results of the practicality of the product get a score percentage of 98.50%. Based on the results, the average pretest score got a score of 33.83 which increased to …

Plasma Homocysteine And Insulin Resistance In Patients With Polycystic Ovary Syndrome, Zahraa Ali Hussain, Anwar Jafar, Abdul H. Al-Nakash

Iraqi Postgraduate Medical Journal

BACKGROUND: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder characterized by multiple hormonal imbalances, reflecting on a clinical presentation dominated by manifestations of hyperandrogenism and insulin resistance. Plasma homocysteine is a non-protein sulfur-containing                α-amino acid plays a role in cardiovascular morbidity and mortality due to its atherogenic and prothrombotic properties. OBJECTIVE: To assess the association between insulin resistance and homocysteine level in women suffering from polycystic ovary syndrome. Study design: A case control study. Setting: Department of Obstetrics and Gynecology at Al-Elwiya Maternity Teaching Hospital during the period from 1st of March 2017 to end of April 2018. MATERIALS AND …

Upconversion, Mri Imaging And Optical Trapping Studies Of Silver Nanoparticle Decorated Multifunctional Nagdf4:Yb,Er Nanocomposite, S. Yamini, M. Gunaseelan, Ajithkumar Gangadharan, Silverio A. Lopez, Karen S. Martirosyan, Agnishwar Girigoswami, Basudev Roy, J. Manonmani, Senthilselvan Jayaraman

Physics & Astronomy Faculty Publications

The multifunctional upconversion nanoparticles (UCNPs) are fascinating tool for biological applications. In the present work, photon upconverting NaGdF4:Yb,Er and Ag nanoparticles decorated NaGdF4:Yb,Er (NaGdF4:Yb,Er@Ag) nanoparticles were prepared using a simple polyol process. Rietveld refinement was performed for detailed crystal structural and phase fraction analysis. The morphology of the NaGdF4:Yb,Er@Ag was examined using high-resolution transmission electron microscope, which reveals silver nanoparticles of 8 nm in size were decorated over spherical shaped NaGdF4:Yb,Er nanoparticles with a mean particle size of 90 nm. The chemical compositions were confirmed by EDAX and inductively coupled plasma-optical emission spectrometry analyses. The upconversion luminescence (UCL) of NaGdF4:Yb,Er …

Pharmacist-Directed Vancomycin Therapeutic Drug Monitoring In Pediatric Patients: A Collaborative-Practice Model, Kashif Hussain, Rahila Ikram, Gul Ambreen, Muhammad Sohail Salat

Department of Biological & Biomedical Sciences

Background: Therapeutic drug monitoring (TDM) of Vancomycin (VCM) is required to prevent inappropriate dosage-associated bacterial resistance, therapeutic failure, and toxicities in pediatrics. Anecdotal experience and studies show that many healthcare institutions confront barriers while implementing TDM services, this study aimed to assess a pharmacist-directed VCM-TDM service for optimizing patient care in our institution.
Materials and methods: Patients aged 1 month-18 years who received intravenous VCM were included in this quasi-experimental study. The pre-implementation phase (March-June 2018) consisted of retrospective assessment of pediatric patients, the interventional phase (July 2018 to February 2020) included educational programs and the post-implementation phase (March-June 2020) …

Bay Leaf Extract‐Based Near‐Infrared Fluorescent Probe For Tissue And Cellular Imaging, Benilde Adriano, Nycol Cotto, Neeraj Chauhan, Vinitha Karumuru, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu

School of Medicine Publications

The development of fluorescence dyes for near‐infrared (NIR) fluorescence imaging has been a significant interest for deep tissue imaging. Among many imaging fluoroprobes, indocyanine green (ICG) and its analogues have been used in oncology and other medical applications. However, these imaging agents still experience poor imaging capabilities due to low tumor targetability, photostability, and sensitivity in the biological milieu. Thus, developing a biocompatible NIR imaging dye from natural resources holds the potential of facilitating cancer cell/tissue imaging. Chlorophyll (Chl) has been demonstrated to be a potential candidate for imaging purposes due to its natural NIR absorption qualities and its wide …

Microplastics Fouling And Interaction With Polymeric Membranes: A Review, Mitra Golgoli, Mehdi H. Khiadani, Abdellah Shafieian, Tushar K. Sen, Y. Hartanto, M. L. Johns, Masoumeh Zargar

Research outputs 2014 to 2021

The emergence and accumulation of microplastics (MPs) in various aquatic environments have recently raised significant concerns. Wastewater treatment plants (WWTPs) have been identified as one of the major sources of MPs discharge to the environment, implying a substantial need to improve advanced techniques for more efficient removal of MPs. Polymeric membranes have been proven effective in MPs removal. However, fouling is the main drawback of membrane processes and MPs can foul the membranes due to their small size and specific surface properties. Hence, it is important to investigate the impacts of MPs on membrane fouling to develop efficient membrane-based techniques …

Clustering Of Aromatic Residues In Prion-Like Domains Can Tune The Formation, State, And Organization Of Biomolecular Condensates, Alex S Holehouse, Garrett M Ginell, Daniel Griffith, Elvan Böke

2020-Current year OA Pubs

In immature oocytes, Balbiani bodies are conserved membraneless condensates implicated in oocyte polarization, the organization of mitochondria, and long-term organelle and RNA storage. In

Berseem Clover In Binary Mixtures With Oats, Triticale Or Barley For Silage And Late Season Grazing, S. M. Ross, J. R. King

IGC Proceedings (1977-2023)

An experiment was conducted at northerly latitudes with berseem clover (Trifolium alexandrinum L) in binary mixtures with oats (Avena sativa L.), barley (Hordeum vulgare L.) and triticale (X Triticosecale Wittmack). The effects of cereal species, variety and density were assessed for a two cut harvest. Total dry matter yields were 11.7 to 14.5 t ha^-1, with 7.8 to 10.2 t ha^-1 as silage, and 2.0 to 6.0 t ha^-1 as berseem regrowth. Berseem regrowth added an average of 4.0 t ha^-1 in forage yield. Total yields did not differ with cereal …