Digital Commons Network^™

Validity, Reliability, And Measurement Invariance Of An Adapted Short Version Of The Hiv Stigma Scale Among Perinatally Hiv Infected Adolescents At The Kenyan Coast, Stanley W. Wanjala, Derrick Ssewanyana, Patrick N. Mwangala, Carophine Nasambu, Esther Chongwo, Stanley Luchters, Charles R. J. C. Newton, Amina Abubakar

Population Health, East Africa

Background: There is a dearth of instruments that have been developed and validated for use with children living with HIV under the age of 17 years in the Kenyan context. We examined the psychometric properties and measurement invariance of a short version of the Berger HIV stigma scale administered to perinatally HIV-infected adolescents in a rural setting on the Kenyan coast.

Methods: A cross-sectional study was conducted among 201 perinatally HIV-infected adolescents aged 12-17 years between November 2017 and October 2018. A short version of the Berger HIV stigma scale (HSS-40) containing twelve items (HSS-12) covering the four dimensions of …

The Predictability Of Selected Academic Demographic And Family Related Factors On The Academic Achievement Of Middle School Students., Demetria Westmoreland

Dissertations (2016-Present)

The purpose of this study was to examine the relationship and predictability of selected demographic, academic and family related factors on the academic performance of middle school students. Specifically, this study will be concerned with the predictability of the variables gender, ethnicity, standardized mathematics scores, standardized reading scores, family income, type of household, socioeconomic status and primary language spoken in the home on the academic performance of middle school students as measured by their STAAR’s social studies scores. A quantitative correlational research design was employed in the current investigation. A linear relationship was not found between the demographic factors of …

The Impact Of Demographic Factors On The Persistence, Study Habits, And Motivation Of African American And Latino Male Community College Students, Martin Perez

Dissertations (2016-Present)

The purpose of this study was to determine the relationship and predictability of demographic factors on the persistence, study habits and motivation level among African American and Latino male community college students. Specifically, this study was concerned with the predictive power of demographic (socio-economic status, age, ethnicity, and family support) factors on the persistence, study habits, and motivation level among minority male community college students. A predictive correlated research design was utilized in the current study. Eighty-three (83) minority male college students were selected to participate in the study. An instrument entitled The Community College Survey of Student Engagement (CCSSE) …

The Impact Of Selective Cognitive And Non-Cognitive Factors On Academic Performance And Persistence Rate Of First-Year College Students: Implications For Counseling., Tanya Sharneek Jones

Dissertations (2016-Present)

The issue of first-year college students academic performance and persistence rate has recently become a focal point for policy discussions because researchers, administrators, counselors, and policymakers are increasingly interested in understanding why some students succeed while others fail. To help incoming freshmen accomplish their academic and career goals, college and universities must gain the necessary insight on how to retain these students and assist them in matriculating on their campuses. Selective cognitive and non-cognitive characteristics associated with incoming freshmen will have a significant impact on them remaining in school and graduating. The purpose of this study was to examine the …

Investigation Of Toxic Chemicals In Plant-Based Milk Alternatives, Chukwunonso A. Anakwue

Dissertations (2016-Present)

Milk is a dietary component consumed all over the world and is known to be essential for development in children. Despite all the nutritional advantages associated with milk consumption, several issues like lactose intolerance, and high lipid content, etc., negatively affects the perception of cow milk consumption, and has grown into general health concerns. Issues with cow milk consumption drove for a healthier alternative and this led to plant-based milk alternatives (PBMA). Several studies have linked consumption of these PBMAs with other negative effects such as: allergy, poor nutrient profile and the presence of other foreign chemicals. This study’s main …

Limitations Of Available Blood Products For Massive Transfusion During Mass Casualty Events At Us Level 1 Trauma Centers, James Williams, Michael Gustafson, Yu Bai, Samuel Prater, Charles E Wade, Oscar D Guillamondegui, Mansoor Khan, Megan Brenner, Paula Ferrada, Derek Roberts, Tal Horer, David Kauvar, Andrew Kirkpatrick, Carlos Ordonez, Bruno Perreira, Artai Priouzram, Juan Duchesne, Bryan A Cotton

Faculty, Staff and Student Publications

INTRODUCTION: Exsanguination remains a leading cause of preventable death in traumatically injured patients. To better treat hemorrhagic shock, hospitals have adopted massive transfusion protocols (MTPs) which accelerate the delivery of blood products to patients. There has been an increase in mass casualty events (MCE) worldwide over the past two decades. These events can overwhelm a responding hospital's supply of blood products. Using a computerized model, this study investigated the ability of US trauma centers (TCs) to meet the blood product requirements of MCEs.

METHODS: Cross-sectional survey data of on-hand blood products were collected from 16 US level-1 TCs. A discrete …

Factors Influencing Us Residents' Willingness To Engage In Domestic Medical Tourism, Hananeh Derakhshan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Domestic medical tourism is a niche market in the medical tourism industry. The purpose of this study was to determine the association of different attributes on U.S residents’ willingness to participate in domestic medical tourism. Based on the medical tourism index (MTI) components, a total of fourteen possible attributes that may impact US residents’ willingness to seek out-of-town care were created and participants were asked to rate the importance of each attribute on their willingness to seek out-of-town care on a 10-point Likert scale. Using principal component analysis, the attributes were grouped into three components: (1) quality-of-care, (2) destination attraction, …

How Can We Reduce Racism? A Mixed Method Study Of Factors That Influence Attitudes Towards Social Change, Kindy Insouvanh

UNLV Theses, Dissertations, Professional Papers, and Capstones

The resurgence of social movements such as Black Lives Matter has provoked public discourse about racial inequality and efforts towards social change. The current study sought to better understand how young adults reason about racism reduction with a focus on racial allyship and collective action. The present study used mixed methods to identify strategies young adults believe different racial groups could do to reduce racism and investigate the influence that individual factors have on reasoning about social change. Here, I present emergent themes to describe racism reduction strategies from a large and racially diverse sample of undergraduate students (N= 428). …

Patient-Derived Ipscs Link Elevated Mitochondrial Respiratory Complex I Function To Osteosarcoma In Rothmund-Thomson Syndrome, Brittany E Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L Underwood, Jun Hyoung Park, Huihui Fan, Julian A Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K Berg, Danielle A Bazer, Christopher Vellano, Philip Jones, Holger K Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L Wang, Dung-Fang Lee

Faculty, Staff and Student Publications

Rothmund-Thomson syndrome (RTS) is an autosomal recessive genetic disorder characterized by poikiloderma, small stature, skeletal anomalies, sparse brows/lashes, cataracts, and predisposition to cancer. Type 2 RTS patients with biallelic RECQL4 pathogenic variants have multiple skeletal anomalies and a significantly increased incidence of osteosarcoma. Here, we generated RTS patient-derived induced pluripotent stem cells (iPSCs) to dissect the pathological signaling leading to RTS patient-associated osteosarcoma. RTS iPSC-derived osteoblasts showed defective osteogenic differentiation and gain of in vitro tumorigenic ability. Transcriptome analysis of RTS osteoblasts validated decreased bone morphogenesis while revealing aberrantly upregulated mitochondrial respiratory complex I gene expression. RTS osteoblast metabolic assays …

Understanding The African American Male Student Experience Of Being Diagnosed With Emotional Disturbance Through The Use Of Counter-Storytelling, Sara Ordaz

Doctoral Dissertations

In the U.S. educational system, it is too common to see African American males overrepresented in special education classrooms, including segregated special education settings. African American males continuously experience disproportionate representation and placement in special education, especially under the label of ED (Harry & Anderson, 1994). Twice as many African American students in the United States are receiving services for Emotional Disturbance than their White counterparts.

Students who are labeled with ED have the lowest educational outcomes as well as lower success rates in life than any other disability classification (Merrrell & Walker, 2004). The consequences of the ED label …

Machine Learning For Unmanned Aerial System (Uas) Networking, Jian Wang

Doctoral Dissertations and Master's Theses

Fueled by the advancement of 5G new radio (5G NR), rapid development has occurred in many fields. Compared with the conventional approaches, beamforming and network slicing enable 5G NR to have ten times decrease in latency, connection density, and experienced throughput than 4G long term evolution (4G LTE). These advantages pave the way for the evolution of Cyber-physical Systems (CPS) on a large scale. The reduction of consumption, the advancement of control engineering, and the simplification of Unmanned Aircraft System (UAS) enable the UAS networking deployment on a large scale to become feasible. The UAS networking can finish multiple complex …

The Effect Of Different Methods To Identify, And Scenarios Used To Address Energy Intake Misestimation On Dietary Patterns Derived By Cluster Analysis, Geraldine Lo Siou, Alianu K. Akawung, Nathan M. Solbak, Kathryn L. Mcdonald, Ala Al Rajabi, Heather K. Whelan, Sharon I. Kirkpatrick

All Works

Background: All self-reported dietary intake data are characterized by measurement error, and validation studies indicate that the estimation of energy intake (EI) is particularly affected. Methods: Using self-reported food frequency and physical activity data from Alberta’s Tomorrow Project participants (n = 9847 men 16,241 women), we compared the revised-Goldberg and the predicted total energy expenditure methods in their ability to identify misreporters of EI. We also compared dietary patterns derived by k-means clustering under different scenarios where misreporters are included in the cluster analysis (Inclusion); excluded prior to completing the cluster analysis (ExBefore); excluded after completing the cluster analysis (ExAfter); …

Exercise And Nutrition Impact On Osteoporosis And Sarcopenia—The Incidence Of Osteosarcopenia: A Narrative Review, Sousana K. Papadopoulou, Konstantinos Papadimitriou, Gavriela Voulgaridou, Evridiki Georgaki, Eudoxia Tsotidou, Olga Zantidou, Dimitrios Papandreou

All Works

Osteoporosis and sarcopenia are diseases which affect the myoskeletal system and often occur in older adults. They are characterized by low bone density and loss of muscle mass and strength, factors which reduce the quality of life and mobility. Recently, apart from pharmaceutical interventions, many studies have focused on non-pharmaceutical approaches for the prevention of osteoporosis and sarcopenia with exercise and nutrition to being the most important and well studied of those. The purpose of the current narrative review is to describe the role of exercise and nutrition on prevention of osteoporosis and sarcopenia in older adults and to define …

Moxie : We Just Wanna Play Games, Chris Stojkos

Postgraduate

Hegemonic geek masculinity dominates video games. It has contributed to the formation of a toxic culture that is now widely perceived to consistently and aggressively prevent women and non-binary gamers from participating as equals. Gaming has historically resisted progressive change, and the industry continues to produce content for the assumed heterosexual male target audience. In more recent years, steps have been taken towards recognising these entrenched issues and implementing change, such as improving gender representation in games, however attempts are inconsistent, and other aspects of the culture are slow to adapt. The gap between the number of male, female, and …

Writing Myths: Interpreting And Translating Meaning, Naomi Robinson

Postgraduate

Myths and stories are integral communication devices that cross both lived and shared experience while manifesting through internal and external meaning-making processes. To determine the nature of myths in and as popular culture, this project sought to use practise-led methods. In addition to storytelling and thematic analysis, this project involved the interpretation and adaptation of an ancient myth into a modern television series. By considering television shows as conduits of socio-political agendas, the creative process culminating in this exegesis highlighted how the perpetual influence of myths through knowledge, reference, and experience can be manipulated to drive cultural change.

As an …

Modeling Watershed Sensitivity To Climate Change In Systems Affected By Discharge Of Mine Tailings, Johnette C. Shockley

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

For more than a century, a large volume of gold-mining tailings was deposited in Whitewood Creek and the Belle Fourche River, tributaries to the Cheyenne River in western South Dakota. Much of it still remains, and field and historical evidence indicates continued remobilization of tailings-containing alluvium in these bedrock-dominated channels. Both long-term, natural fluctuations in climate and anthropogenically driven changes can impact regional precipitation, temperature, hydrologic patterns, and ecosystem functions. Such changes have the potential to affect both the transport and distribution of arsenic-laden sediments and mechanical erosion that can undermine the stability of channel-bed and overbank material.

This study …

Ageing American Kestrels In-Hand, William S. Clark, Jill Morrow, Lance Morrow, Jeffery J. Kolodzinski

North American Bird Bander

No abstract provided.

Recent Literature, C. John Ralph

North American Bird Bander

No abstract provided.

From The New Chief Of The Bird Banding Laboratory, Antonio Celis-Murillo

North American Bird Bander

No abstract provided.

The Pest Kill Rate Of Thirteen Natural Enemies As Aggregate Evaluation Criterion Of Their Biological Control Potential Of Tuta Absoluta, Joop C. Van Lenteren, Alberto Lanzoni, Lia Hemerik, Vanda H.P. Bueno, Johanna G. Bajonero Cuervo, Antonio Biondi, Giovanni Burgio, Francisco J. Calvo, Peter W. De Jong, Silvia N. López, M. Gabriela Luna, Flavio C. Montes, Eliana L. Nieves, Pascal Osa Aigbedion-Atalor, Maria B. Riquelme Virgala, Norma E. Sánchez, Alberto Urbaneja

All Peer-Reviewed Publications

Ecologists study how populations are regulated, while scientists studying biological pest control apply population regulation processes to reduce numbers of harmful organisms: an organism (a natural enemy) is used to reduce the population density of another organism (a pest). Finding an effective biological control agent among the tens to hundreds of natural enemies of a pest is a daunting task. Evaluation criteria help in a first selection to remove clearly ineffective or risky species from the list of candidates. Next, we propose to use an aggregate evaluation criterion, the pest kill rate, to compare the pest population reduction capacity of …

Global Population Genetic Structure And Demographic Trajectories Of The Black Soldier Fly, Hermetia Illucens, Cengiz Kaya, Tomas N. Generalovic, Gunilla Ståhls, Martin Hauser, Ana C. Samayoa, Carlos G. Nunes-Silva, Heather Roxburgh, Jens Wohlfahrt, Ebenezer A. Ewusie, Marc Kenis, Yupa Hanboonsong, Jesus Orozco, Nancy Carrejo, Satoshi Nakamura, Laura Gasco, Santos Rojo, Chrysantus M. Tanga, Rudolf Meier, Clint Rhode, Christine J. Picard, Chris D. Jiggins, Florian Leiber, Jeffery K. Tomberlin, Martin Hasselmann, Wolf U. Blanckenhorn, Martin Kapun, Christoph Sandrock

All Peer-Reviewed Publications

Background: The black soldier fly (Hermetia illucens) is the most promising insect candidate for nutrient-recycling through bioconversion of organic waste into biomass, thereby improving sustainability of protein supplies for animal feed and facilitating transition to a circular economy. Contrary to conventional livestock, genetic resources of farmed insects remain poorly characterised. We present the first comprehensive population genetic characterisation of H. illucens. Based on 15 novel microsatellite markers, we genotyped and analysed 2862 individuals from 150 wild and captive populations originating from 57 countries on seven subcontinents. Results: We identified 16 well-distinguished genetic clusters indicating substantial global population structure. The data …

The Efficacy Of A Rapid Rehousing Program Serving Adults Experiencing Homelessness In West Central Texas, Unique Jackson

Electronic Theses and Dissertations

This thesis discusses the dynamics of homelessness and examines one agency (Abilene Hope Haven) that aims to help homeless individuals receive permanent housing. This study explores the characteristics that influence the likelihood of placement in permanent housing within 12 months at Abilene Hope Haven. The different types of supportive housing programs and their roles in helping homeless individuals will be discussed. Secondary data gathered from the Homeless Management Information System were entered into the Statistical Package for Social Sciences, and then a logistical regression analysis was created to explain the relationships between the different characteristics and permanency placement. A key …

The Philosophy Of Outliers: Reintegrating Rare Events Into Biological Science, Chelsea N. Cook, Angela R. Freeman, James C. Liao, Lisa A. Mangiamele

Biological Sciences: Faculty Publications

Individual variation in morphology, physiology, and behavior has been a topic of great interest in the biological sciences.While scientists realize the importance of understanding diversity in individual phenotypes, historically the minority results (i.e., outlier observations or rare events) of any given experiment have been dismissed from further analysis. We need to reframe how we view outliers to improve our understanding of biology. These rare events are often treated as problematic or spurious, when they can be real rare events or individuals driving evolution in a population. It is our perspective that to understand what outliers can tell us in our …

The Causal Effects Of Growing Up In A Two-Parent Household: Evidence From The Psid On Schooling, Earnings, And Labor Force Participation, Bob Shihao Wen

All Dissertations

The children who grew up in a two-parent household earn more than the other children reared in non-intact parental families. The causal effects of growing up in a two-parent household can be identified using two specification strategies. First, I include the parental household income and educational attainment in the model, along with the child’s demographic characteristics (age, gender, race, and state of residence), to disentangle the childhood family structure effect from the other parental influence. Second, I use the average state divorce rate over the child’s first 16 years of childhood and the childhood years of exposure to the no-fault …

Influencing The Inflammatory Response Through Multi-Scale Geometry, Antibiotic Release, And Fluid Management In A Textile-Based Biomaterial Wound Dressing, Elizabeth Gianino

All Dissertations

The total population of diagnosed and undiagnosed diabetes mellitus in the United states is expected to rise by 54% between the years of 2015 and 2030 contributing to $200 billion in health care expense. The exponential rise in common diabetic wounds, such as diabetic foot ulcers, puts a large population at risk for complications such as infection, amputation, and even death. Peripheral neuropathy leading to late diagnoses, patient non-compliance, and lack of holistic treatment options all contribute to complications with the incidence of new ulcer formation after treatment reaching 50%. This work explores the design, development, and in vitro evaluation …

Capillary Driven Transport In Soft Solids, Saiful Islam Tamim

All Dissertations

Soft solids, such as polymeric gels, are elastic materials that can be significantly deformed by capillary forces which act at the interface. The coupling between elasticity and capillarity is known as elastocapillarity and is useful to wide ranging applications, from drop pinchoff of bioinks for 3-D printing tissue scaffolds, to generating droplet patterns on microfluidic devices. In this dissertation, we develop mathematical models of elastocapillary driven motions in soft solids. The focus is on understanding the relevant physics in such complex phenomena, while also recovering the limiting cases of classical fluid mechanics and solid mechanics theories.

This dissertation investigates two …

Identification Of Biomarker Systems Of Autism Spectrum Disorder And Uterine Cancer, Allison Hickman

All Dissertations

Complex diseases and disorders pose a challenge to scientists due to their variable and often inconsistent genetic and environmental underpinnings across affected individuals. Because of this variability, large condition-specific datasets and corresponding analytical tools and approaches are being curated as resources to investigate potential genetic trends in complex diseases and disorders. In this Dissertation, I used DNA- and RNA-based resources to discover polygenic biosignatures associated with Autism Spectrum Disorder (ASD) or uterine cancer. To explore the intersection of small-effect common DNA variants and regulation in ASD, I discovered and analyzed trends in allelic associations at eQTLs within ASD-affected individuals. Association …

Understanding And Modulating Amyloid Aggregation, Yanting Xing

All Dissertations

Amyloids are the products of protein misfolding into fibril-like structures, which take place in human tissues and organs, including the human brain, heart, liver, and pancreas. As the deposition of amyloid fibrils usually leads to the dysfunction or death of cells, the formation of amyloid is associated with more than 20 human diseases, such as Alzheimer’s, Parkinson’s, and type 2 diabetes. Understanding how soluble peptides to form amyloid fibrils and how to modulate those amyloid aggregation are central to the design of rational therapeutic strategies against those diseases. Increasing experiments suggest that amyloid peptides can undergo liquid-liquid phase separation (LLPS) …

Exploring The Role Of Ampk In Nutrient Sensing And Signaling In The Human Parasite Trypanosoma Brucei, Jessica Jones

All Dissertations

African trypanosomes are protozoan parasites that cause the diseases African sleeping sickness and nagana, in humans and cattle respectively. These parasites have complex life cycles with infection of a mammalian host, ~5mM glucose, following transmission by an insect vector, essentially zero glucose. With these pathogens being exposed to rapidly changing glucose abundance in a host-dependent manner, the ability to sense and rapidly respond to changes in the availability of the hexose are critical. First, I provide a review of glucose metabolism in Trypanosoma brucei. Then, we explore the role of the catalytic α subunit of AMPK, a eukaryotic master …

Development Of Tissue Engineered Scaffolds For Cardiovascular Repair And Replacement In Pediatric Patients, Dipasha Sinha

All Dissertations

Congenital Heart Diseases (CHD) are abnormalities present in the heart and great vessels at birth. It is one of the most frequently diagnosed congenital disorders, affecting approximately 40,000 live birth each year in the United States. The incidence of new CHD patients and the relative distribution of defects have not changed over time and remain a birth rate function. Out of the new patients found to have CHD each year, an estimated 2,500 patients have a defect that requires a substitute, non-native valve, or conduit artery to replace structures that are congenitally absent or hypoplastic. Materials in current use for …