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Maternal Investment, Life-History Trajectory Of The Off-Spring And Cardiovascular Disease Risk In Emirati Females In The United Arab Emirates, Rola Al Ghali, Linda Smail, Maryam Muqbel, Dalia Haroun

All Works

Background: Variations in cardiovascular disease risk (CVD) are suggested to be partly influenced by factors that affect prenatal growth patterns and outcomes, namely degree of maternal investment (proxied by birth weight and gestational age). Using the life history trajectory model, this study investigates whether maternal investment in early prenatal life associates with menarcheal age and whether maternal investment affects CVD risk in adulthood and predicts adult size and adiposity levels. Methods: A cross-sectional study was conducted among 94 healthy Emirati females. Birth weight, gestational age and menarcheal age were obtained. Anthropometrical measurements, body composition analysis, and blood pressure values were …

The Role Of The Next Generation Science Standards In Teachers' Curricular Choices In The Life Science Classroom, Amy Tankersley

Department of Teaching, Learning, and Teacher Education: Theses and Other Student Research

In 2013 a group of experts used A Framework for K-12 Science Education (NRC, 2012) to draft the Next Generation Science Standards (NGSS), which aims to increase science literacy through integrating the concepts and practices of science into comprehensive standards for science (NGSS Lead States, 2013). As students learn to explore the content and practices of scientists, ideally, they should increase their ability to think and reason in ways that will benefit their ability to participate in society. Because of the complex nature of systematic education reform, teachers need to put significant time into implementing NGSS to fulfill the goals …

The Association Of Step-Based Metrics And Adiposity In The Hispanic Community Health Study/Study Of Latinos., Samantha Schilsky, Daniela Sotres-Alvarez, Wayne D. Rosamond, Gerardo Heiss, June Stevens, Nicole Butera, Jianwen Cai, Jordan A. Carlson, Carmen Cuthbertson, Martha Daviglus, Madison N. Lecroy, Amber Pirzada, Kelly R. Evenson

Manuscripts, Articles, Book Chapters and Other Papers

Objective: Examine cross-sectional and longitudinal associations of accelerometer measured step volume (steps/day) and cadence with adiposity and six-year changes in adiposity in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Methods: HCHS/SOL's target population was 60% female with a mean age of 41 years. Cross-sectional (n = 12,353) and longitudinal analyses (n = 9,077) leveraged adjusted complex survey regression models to examine associations between steps/day, and cadence with weight (kg), waist circumference (cm) and body mass index (kg/m2). Effect measure modification by covariates was examined.

Results: Lower steps/day and intensity was associated with higher adiposity at baseline. Compared to those …

Prenatal Risk Factors And Neonatal Dna Methylation In Very Preterm Infants, Marie Camerota, Stefan Graw, Todd M. Everson, Elisabeth C. Mcgowan, Julie A. Hofheimer, T. Michael O’Shea, Brian S. Carter, Jennifer B. Helderman, Jennifer Check, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Lynne M. Dansereau, Sheri A. Dellagrotta, Carmen J. Marsit, Barry M. Lester

Manuscripts, Articles, Book Chapters and Other Papers

Background: Prenatal risk factors are related to poor health and developmental outcomes for infants, potentially via epigenetic mechanisms. We tested associations between person-centered prenatal risk profiles, cumulative prenatal risk models, and epigenome-wide DNA methylation (DNAm) in very preterm neonates. Methods: We studied 542 infants from a multi-center study of infants born < 30 weeks postmenstrual age. We assessed 24 prenatal risk factors via maternal report and medical record review. Latent class analysis was used to define prenatal risk profiles. DNAm was quantified from neonatal buccal cells using the Illumina MethylationEPIC Beadarray. Results: We identified three latent profiles of women: a group with few risk factors (61%) and groups with elevated physical (26%) and psychological (13%) risk factors. Neonates born to women in higher risk subgroups had differential DNAm at 2 CpG sites. Higher cumulative prenatal risk was associated with methylation at 15 CpG sites, 12 of which were located in genes previously linked to physical and mental health and neurodevelopment. Conclusion: We observed associations between prenatal risk factors and DNAm in very preterm infants using both person-centered and cumulative risk approaches. Epigenetics offers a potential biological indicator of prenatal risk exposure.

Cdk5 Drives Formation Of Heterogeneous Pancreatic Neuroendocrine Tumors, Angela M. Carter, Nilesh Kumar, Brendon Herring, Chunfeng Tan, Rachael Guenter, Rahul Telange, Wayne Howse, Fabrice Viol, Tyler R. Mccaw, Hayden H. Bickerton, Priyanka Gupta, Frank Gillardon, Eugene A. Woltering, Deepti Dhall, John Totenhagen, Ronadip R. Banerjee, Elizabeth M. Kurian, Sushanth Reddy, Herbert Chen, Joerg Schrader

School of Medicine Faculty Publications

Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous population of neoplasms that arise from hormone-secreting islet cells of the pancreas and have increased markedly in incidence over the past four decades. Non-functional PanNETs, which occur more frequently than hormone-secreting tumors, are often not diagnosed until later stages of tumor development and have poorer prognoses. Development of successful therapeutics for PanNETs has been slow, partially due to a lack of diverse animal models for pre-clinical testing. Here, we report development of an inducible, conditional mouse model of PanNETs by using a bi-transgenic system for regulated expression of the aberrant activator of Cdk5, …

Passive Immunity Trial For Our Nation (Passiton): Study Protocol For A Randomized Placebo-Control Clinical Trial Evaluating Covid-19 Convalescent Plasma In Hospitalized Adults, Wesley H. Self, Thomas G. Stewart, Allison P. Wheeler, Wissam El Atrouni, Amanda J. Bistran-Hall, Jonathan D. Casey, Vince D. Cataldo, James D. Chappell, Claudia S. Cohn, Jessica B. Collins, Mark R. Denison, Marjolein De Wit, Sheri L. Dixon, Abhijit Duggal, Terri L. Edwards, Magali J. Fontaine, Adit A. Ginde, Michelle S. Harkins, Thelma Harrington, Estelle S. Harris

School of Medicine Faculty Publications

Background: Convalescent plasma is being used widely as a treatment for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of COVID-19 convalescent plasma is unclear. Methods: The Passive Immunity Trial for Our Nation (PassITON) is a multicenter, placebo-controlled, blinded, randomized clinical trial being conducted in the USA to provide high-quality evidence on the efficacy of COVID-19 convalescent plasma as a treatment for adults hospitalized with symptomatic disease. Adults hospitalized with COVID-19 with respiratory symptoms for less than 14 days are eligible. Enrolled patients are randomized in a 1:1 ratio to 1 unit (200–399 mL) of COVID-19 convalescent plasma that has …

Phenology Dictates The Impact Of Climate Change On Geographic Distributions Of Six Co-Occurring North American Grasshoppers, Nathan P. Lemoine

Biological Sciences Faculty Research and Publications

Throughout the last century, climate change has altered the geographic distributions of many species. Insects, in particular, vary in their ability to track changing climates, and it is likely that phenology is an important determinant of how well insects can either expand or shift their geographic distributions in response to climate change. Grasshoppers are an ideal group to test the hypothesis that phenology correlates with range expansion, given that co-occurring confamilial, and even congeneric, species can differ in phenology. Here, I tested the hypothesis that early- and late-season species should possess different range expansion potentials, as estimated by habitat suitability …

Herbivores Alleviate The Negative Effects Of Extreme Drought On Plant Community By Enhancing Dominant Species, Chong Xu, Yuguang Ke, Honghui Wu, Melinda D. Smith, Nathan P. Lemoine, Weiguo Zhang, Qiang Yu

Biological Sciences Faculty Research and Publications

Aims

Both extreme drought and insect herbivores can suppress plant growth in grassland communities. However, most studies have examined extreme drought and insects in isolation, and there is reason to believe that insects might alter the ability of grasslands to withstand drought. Unfortunately, few studies have tested the interactive effects of extreme drought and insect herbivores in grassland communities.

Methods

Here, we tested the drought–herbivore interactions using a manipulative experiment that factorially crossed extreme drought with the exclusion of insect herbivores in a temperate semiarid grassland in Inner Mongolia.

Important Findings

Our results demonstrated that both extreme drought and insect …

Co-Option Of The Yolkless Oocyte Receptor For Crispr/Cas9 May Induce Transient Sterility In Female Drosophila Grimshawi Flies, Bronwyn Miller

LSU New Orleans Theses and Dissertations

Evolutionary developmental biology has historically used generalist model organisms like Drosophila melanogaster. The Hawaiian Drosophilidae radiation, which occurred just 25 million years ago, is an ideal lineage for work in Evo-Devo. Hawaiian flies make up 25% of the world’s Drosophila species and extreme diversity is seen throughout the group. D. grimshawi is a generalist Hawaiian picture-wing fly that has served as a model for the Hawaiian Drosophilidae radiation. However, D. grimshawi’s power and use as a model organism is constrained by our lack of ability to manipulate its genome. In this work, I attempted to edit the genome of …

Kudzu Invasion And Control In Southern Upland Forests Of Mississippi, Gina M. Profetto

LSU New Orleans Theses and Dissertations

Kudzu, Pueraria montana var. lobata (Willd.), is a common invasive species throughout the American South. In southern upland mixed oak-pine forests of Mississippi, kudzu invasion generally and indiscriminately suppressed the pre-invasion plant community. Three different control methods reduced kudzu density but differed in the level of reduction achieved and in their effects on the pre-existing plant community. A combination of burning and herbicides produced the most desirable outcome in terms of restoring the pre-invasion community. Kudzu invasion significantly increased nitrate pools compared to control sites, but had no effect on ammonium or nitrite, or on the microbial processes of mineralization …

Alterations In Excitatory And Inhibitory Synaptic Development Within The Mesolimbic Dopamine Pathway In A Mouse Model Of Prenatal Drug Exposure, Taylor Boggess, James C. Williamson, Ethan B. Niebergall, Hannah Sexton, Richard D. Egleton, Larry Grover, Chris Risher

Biomedical Sciences

The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved understanding of NAS and its acute symptoms, there remains a paucity of information regarding the long-term effects of prenatal exposure to drugs of abuse on neurological development. The primary goal of this study was to investigate the effects of prenatal drug exposure on synaptic connectivity within brain regions associated with the mesolimbic dopamine pathway, the primary reward pathway associated with drug abuse and addiction, in a mouse model. Our secondary …

Socio-Economic And Environmental Issues: Implications For Food Security In Nigeria, Isaiah O. Olurinola, Evans Osabuohien

Economic and Financial Review

Socio-economic activities within the agricultural sector have witnessed significant changes in recent times. Two major factors account for this recent development. Available evidence shows that over the last four decades, environmental challenges (such as pollution, extreme weather, fire disaster and deforestation, among others) have been on the increase in Nigeria. This is complicated by a weak institutional framework to stem the tide (Egbetokun et al., 2018; 2020). Also, the information from Nigeria Meteorological Agency (NIMET) shows that the annual mean climatic conditions (that is rainfall and temperature) in Nigeria have witnessed huge variation (NIMET, 2020; Egbetokun et al., 2020), which …

Socio-Economic And Environmental Issues: Implications For Food Security In Nigeria, Isaiah O. Olurinola, Evans Osabuohien

Economic and Financial Review

Nigeria has made many policies toward improving the contribution of the agricultural sector in the economy; however, there is a need to fine-tune some of the policies, particularly regarding food security.

There is a need for systemic intervention in the transformation of the agricultural sector including the modernisation/formalisation of the informal sector. T

Therefore, this paper sets out to, among others, investigate the state of food security in Nigeria, especially in relation to the current socio-economic and environmental issues affecting agricultural productivity, and then proffers some policy analytical models and recommendations for ensuring food security in the country.

(R1412) Stability And Bifurcation Of A Cholera Epidemic Model With Saturated Recovery Rate, Huda Abdul-Satar, Raid K. Naji

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, a Cholera epidemic model is proposed and studied analytically as well as numerically. It is assumed that the disease is transmitted by contact with Vibrio cholerae and infected person according to dose-response function. However, the saturated treatment function is used to describe the recovery process. Moreover, the vaccine against the disease is assumed to be utterly ineffective. The existence, uniqueness and boundedness of the solution of the proposed model are discussed. All possible equilibrium points and the basic reproduction number are determined. The local stability and persistence conditions are established. Lyapunov method and the second additive compound …

A Linear Dynamical Perspective On Epidemiology: Interplay Between Early Covid-19 Outbreak And Human Mobility, Shakib Mustavee

Electronic Theses and Dissertations, 2020-2023

This research investigates the impact of human activity and mobility (HAM) in the spreading dynamics of an epidemic. Specifically, it explores the interconnections between HAM and its effect on the early spread of the COVID-19 virus. During the early stages of the pandemic, effective reproduction numbers exhibited a high correlation with human mobility patterns, leading to a hypothesis that the HAM system can be studied as a coupled system with disease spread dynamics. This study applies the generalized Koopman framework with control inputs to determine the nonlinear disease spread dynamics and the input-output characteristics as a locally linear controlled dynamical …

Serine/Threonine Protein Phosphatase 1-Α (Stpp1-Α) From Black Tiger Shrimp, Penaeus Monodon, An Immune-Related Gene, Jacqueline Marjorie Pereda, Neil Andrew Bascos, Mudjekeewis Santos

The Philippine Agricultural Scientist

Reversible protein phosphorylation is a significant regulatory mechanism in many cellular functions, such as the dephosphorylation of Serine/Threonine protein residues catalyzed by protein phosphatase. In this study, the full-length STPP1-α gene from Penaeus monodon was cloned, characterized, and analyzed for its constitutive expression in WSSV-negative P. monodon organs. The gene was originally an isotig isolated from the gills of P. monodon that survived WSSV infection. PmSTPP1-α gene (GenBank: KX385833) has a total of 2 171 bp, with a 990 open reading frame (ORF) that encodes 329 amino acids (aa), sharing a 93% sequence identity with human Serine/Threonine PP1-α …

Rearing Silver Therapon Leiopotherapon Plumbeus (Teleostei: Terapontidae) Larvae Using Euryhaline Rotifers As Starter Food, Frolan A. Aya, Vicar Stella Nillasca, Luis Maria B. Garcia

The Philippine Agricultural Scientist

The silver therapon Leiopotherapon plumbeus is an important but dwindling freshwater food commodity in the Philippine freshwater habitats. The influence of feeding regimes on growth performance and survival of first-feeding silver therapon larvae fed euryhaline rotifers (Brachionus rotundiformis and B. plicatilis) as starter food was examined. Larvae at two days post-hatch (DPH) (1.93 ± 0.07 mm; 200 larvae/basin) were initially reared on rotifers for 12 days followed by Artemia nauplii from 14 to 35 DPH as follows: (A) B. rotundiformis from 2-13 DPH; (B) B. rotundiformis from 2-7 DPH and Moina micrura from 8-13 DPH; and (C) B. …

Association Of Serum Magnesium With Blood Pressure In Patients With Hypertensive Crises: A Retrospective Cross-Sectional Study, Ifeanyichukwu O. Onor, Lashira M. Hill, Modupe M. Famodimu, Mallory R. Coleman, Carolkim H. Huynh, Robbie A. Beyl, Casey J. Payne, Emily K. Johnston, John I. Okogbaa, Christopher J. Gillard, Daniel F. Sarpong, Amne Borghol, Samuel C. Okpechi, Ifeyinwa Norbert, Shane E. Sanne, Shane G. Guillory

School of Graduate Studies Faculty Publications

The role of magnesium in blood pressure has been studied among hypertensive patients; however, there is a dearth of studies exploring the role of magnesium in hypertensive crises. The primary objective of this study was to evaluate the relationship between serum magnesium and blood pressure in patients with hypertensive crises. This was a singlecenter, retrospective, chart review, cross-sectional study of patients with hypertensive crises. Patients were included if they were eighteen years of age or older, with an international classification disease ninth revision (ICD-9) code of 401.9 (hypertensive crises: emergency or urgency) and a documented magnesium level on their electronic …

Ampk Modulation Ameliorates Dominant Disease Phenotypes Of Ctrp5 Variant In Retinal Degeneration, Kiyoharu J. Miyagishima, Ruchi Sharma, Malika Nimmagadda, Katharina Clore-Gronenborn, Zoya Qureshy, Davide Ortolan, Devika Bose, Mitra Farnoodian, Congxiao Zhang, Andrew Fausey, Yuri V. Sergeev, Mones Abu-Asab, Bokkyoo Jun, Khanh V. Do, Marie Audrey Kautzman Guerin, Jorgelina Calandria, Aman George, Bin Guan, Qin Wan, Rachel C. Sharp

School of Graduate Studies Faculty Publications

Late-onset retinal degeneration (L-ORD) is an autosomal dominant disorder caused by a missense substitution in CTRP5. Distinctive clinical features include sub-retinal pigment epithelium (RPE) deposits, choroidal neovascularization, and RPE atrophy. In induced pluripotent stem cells-derived RPE from L-ORD patients (L-ORD-iRPE), we show that the dominant pathogenic CTRP5 variant leads to reduced CTRP5 secretion. In silico modeling suggests lower binding of mutant CTRP5 to adiponectin receptor 1 (ADIPOR1). Downstream of ADIPOR1 sustained activation of AMPK renders it insensitive to changes in AMP/ATP ratio resulting in defective lipid metabolism, reduced Neuroprotectin D1(NPD1) secretion, lower mitochondrial respiration, and reduced ATP production. These metabolic …

Winter Cover Crop Mixes: Effects On Strip-Tilled Plasticulture And No-Till Watermelon Production In Arkansas, Alden Neil Hotz

Graduate Theses and Dissertations

Watermelon, Citrullus lanatus (Thunb.) Matsum. & Nakai, producers in Arkansas grow watermelons in either plasticulture or bare-ground systems. Both systems can benefit from the use of winter cover crops for weed control and to supply nitrogen (N) to the watermelon crop. Currently, the use of cover crops in watermelon production in AR is mostly limited to either cereal rye (Secale cereale L.) or winter wheat (Triticum aestivum L). The objective of this research is to evaluate the potential benefits of growing a mix of a legume and grass cover crops before watermelon production in both a strip-till plasticulture and a …

Higher Habitual Flavonoid Intakes Are Associated With A Lower Risk Of Peripheral Artery Disease Hospitalizations, Nicola P. Bondonno, Kevin Murray, Aedin Cassidy, Catherine P. Bondonno, Joshua Lewis, Kevin D. Croft, Cecilie Kyro, Gunnar Gislason, Christian Torp-Pedersen, Augustin Scalbert, Anne Tjonneland, Jonathan M. Hodgson, Frederik Dalgaard

Research outputs 2014 to 2021

Background

The role of nutrition in the primary prevention of peripheral artery disease (PAD), the third leading cause of atherosclerotic cardiovascular disease, is undetermined. Flavonoids may attenuate atherosclerosis and therefore persons who consume flavonoid-rich foods may have a lower risk of developing PAD.

Objectives

We aimed to examine the association between flavonoid intake and PAD hospitalizations and investigate if the association differs according to established risk factors for PAD.

Methods

Baseline data from 55,647 participants of the Danish Diet, Cancer, and Health Study without PAD, recruited from 1993 to 1997, were cross-linked with Danish nationwide registries. Flavonoid intake was calculated …

The Use Of Singlebeam Echo-Sounder Depth Data To Produce Demersal Fish Distribution Models That Are Comparable To Models Produced Using Multibeam Echo-Sounder Depth, Marcela Montserrat Landero Figueroa, Miles J. G. Parsons, Benjamin J. Saunders, Ben Radford, Chandra Salgado-Kent, Iain M. Parnum

Research outputs 2014 to 2021

Seafloor characteristics can help in the prediction of fish distribution, which is required for fisheries and conservation management. Despite this, only 5%–10% of the world's seafloor has been mapped at high resolution, as it is a time-consuming and expensive process. Multibeam echo-sounders (MBES) can produce high-resolution bathymetry and a broad swath coverage of the seafloor, but require greater financial and technical resources for operation and data analysis than singlebeam echo-sounders (SBES). In contrast, SBES provide comparatively limited spatial coverage, as only a single measurement is made from directly under the vessel. Thus, producing a continuous map requires interpolation to fill …

Analysis Of Circulating Tumour Cells In Early-Stage Uveal Melanoma: Evaluation Of Tumour Marker Expression To Increase Capture, Aaron B. Beasley, Timothy W. Isaacs, Tersia Vermeulen, James Freeman, Jean-Louis De Sousa, Riyaz Bhikoo, Doireann Hennessy, Anna Reid, Fred K. Chen, Jacqueline Bentel, Daniel Mckay, R. Max Conway, Michelle R. Pereira, Bob Mirzai, Leslie Calapre, Wendy N. Erber, Melanie R. Ziman, Elin S. Gray

Research outputs 2014 to 2021

Background:

The stratification of uveal melanoma (UM) patients into prognostic groups is critical for patient management and for directing patients towards clinical trials. Current classification is based on clinicopathological and molecular features of the tumour. Analysis of circulating tumour cells (CTCs) has been proposed as a tool to avoid invasive biopsy of the primary tumour. However, the clinical utility of such liquid biopsy depends on the detection rate of CTCs.

Methods:

The expression of melanoma, melanocyte, and stem cell markers was tested in a primary tissue microarray (TMA) and UM cell lines. Markers found to be highly expressed in primary …

Multi-Marker Immunofluorescent Staining And Pd-L1 Detection On Circulating Tumour Cells From Ovarian Cancer Patients, Du-Bois Asante, Michael Morici, Ganendra R. K. A. Mohan, Emmanuel Acheampong, Isaac Spencer, Weitao Lin, Paula Van Miert, Samantha Gibson, Aaron B. Beasley, Melanie Ziman, Leslie Calapre, Tarek M. Meniawy, Elin S. Gray

Research outputs 2014 to 2021

Detection of ovarian cancer (OC) circulating tumour cells (CTCs) is primarily based on targeting epithelial markers, thus failing to detect mesenchymal tumour cells. More importantly, the immune checkpoint inhibitor marker PD-L1 has not been demonstrated on CTCs from OC patients. An antibody staining protocol was developed and tested using SKOV-3 and OVCA432 OC cell lines. We targeted epithelial (cytokeratin (CK) and EpCAM), mesenchymal (vimentin), and OC-specific (PAX8) markers for detection of CTCs, and CD45/16 and CD31 were used for the exclusion of white blood and vascular endothelial cells, respectively. PD-L1 was used for CTC characterisation. CTCs were enriched using the …

Host Defence Peptides In Diabetes Mellitus Type 2 Patients With Periodontal Disease. A Systematic Review, Muhammad Saad Shaikh, Muhammad Sohail Zafar, Farhan Saleem, Ahmad Alnazzawi, Mohid Abrar Lone, Syed Jawad Ali Bukhari, Zohaib Khurshid

Research outputs 2014 to 2021

The aim of the study was to critically assess and review the latest evidence relating the associations between host defence peptides (HDPs), periodontal diseases (PD) and diabetes mellitus type 2 (DM2). To explore studies on HDPs, periodontal disease, and DM2, researchers utilised specific key phrases to search the electronic databases PubMed (National Library of Medicine), Embase (Ovid), Medline (EBSCO), and Dentistry and Oral Sciences (EBSCO). Quality assessment was conducted by means of the Newcastle Ottawa scale and the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) tool. Following a thorough screening process, a total of 12 papers (4 case‐control, 6 …

Nano-Grating Assisted Light Absorption Enhancement For Msm-Pds Performance Improvement: An Updated Review, Narottam Das, Mohammad Nur-E-Alam, Alif Islam, Ain Zulaikha Maslihan Ain

Research outputs 2014 to 2021

The primary focus of this review article mainly emphasizes the light absorption enhancement for various nanostructured gratings assisted metal-semiconductor-metal photodetectors (MSM-PDs) that are so far proposed and developed for the improvement of light capturing performance. The MSM-PDs are considered as one of the key elements in the optical and high-speed communication systems for applications such as faster optical fiber communication systems, sensor networks, high-speed chip-to-chip interconnects, and high-speed sampling. The light absorption enhancement makes the MSM-PDs an ideal candidate due to their excellent performances in detection, especially in satisfying the high-speed or high-performance device requirements. The nano-grating assisted MSM-PDs are …

Augmented Reality-Assisted Problem-Based Learning E-Module To Improve Problem-Solving Skills, Zurienia Mimi Bibiyana, Fatchur Rohman, Mimien Henie Irawati Al-Muhdhar

Jurnal Pendidikan Sains

Problem-solving skills in the field of biology play an important role in representing problems, identifying relationships, making predictions, and verifying or evaluating solutions. This study aimed to implement an augmented reality-assisted problem-based learning e-module on bioindicator materials to improve students’ problem-solving skills. The research method used was a pre-experimental one-group pretest-posttest design involving 29 biology students at the State University of Malang in the 2020/2021 academic year. The results of the paired t-test showed that the significance value (p) for the pretest and posttest was 0.000 (< 0.05), indicating that the e-module had a significant effect on improving students’ problem-solving skills.

Literature Review: Analysis Of Physical Activity In Physical Education Learning On Optimizing Students’ Neuromuscular System, Prima Suci Ibar Wati Ningrum, Sugiharto Sugiharto, Sapto Adi

Jurnal Pendidikan Sains

This literature review aimed to analyze the optimization of students’ neuromuscular systems through physical activity in physical education learning. Articles were collected from four databases—Google Scholar, ScienceDirect, Hindawi, and PubMed—covering publications from the last ten years (2011–2021). The keywords used in searching and analyzing the relevant articles included physical education, physical activity, neuromuscular, neurotransmitters, acetylcholine, dopamine, motor function, and student. Data extraction and analysis were conducted using the PRISMA flowchart method. The analysis of 30 articles showed that physical education learning influences the optimization of acetylcholine and dopamine, as well as the optimization of the neuromuscular system in performing movement …

Recapture And Reuse Of Nitrogen And Phosphorus From Rendered Animal Materials To Enhance Nutrient Use Efficiency And Produce Quality In Agricultural Crop, Bhupinder Jatana

All Dissertations

The current fertilizer regime heavily relies on inorganic fertilizers to meet the crop nitrogen (N) and phosphorus (P) demand. However, the United States has a limited N production capacity, with 50% N demand met through imports. On the other hand, the nonrenewable natural reserves of P are being depleted at an unprecedented rate and are expected to be exhausted with in next 100 years. Additionally, high solubility/liability of the field applied inorganic fertilizers often results in lower nutrient use efficiency (NUE;

The MBM led to rapid N mineralization, with 35% of the applied N mineralized within the first five days …

Characterization Of The Respiratory Syncytial Virus (Rsv) Attachment Protein Mucin Domains, Molly Kathleen Roe

Undergraduate Honors Thesis Collection

Respiratory Syncytial Virus (RSV) is currently a leading cause of acute lower respiratory infection (ALRI). Despite contributing to a significant mortality rate in young children and immunocompromised populations, it still lacks a vaccine. Live-attenuated vaccines are the preferred vaccination model for RSV, but achieving attenuation, immunogenicity, and stability can be difficult. Previous studies have indicated that deletion of the RSV G protein attenuates viral replication, but the role of the protein’s mucin domains has not been fully explored. We generate two new RSV strains here with varying G protein deletions: A2-line19F-G155 with deletion of the G-protein mucin domains, and A2- …