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Association Between Meal Dietary Inflammatory Potential And Postprandial Sleepiness, Samantha Beth Kalb Dec 2021

Association Between Meal Dietary Inflammatory Potential And Postprandial Sleepiness, Samantha Beth Kalb

Master's Theses

The amount and composition of food that is consumed are known to contribute toinflammation and may affect how we feel in the following hours. The aim of this research was to determine if the inflammatory potential of a single meal is associated with level of postprandial sleepiness. Participants (n = 70) recorded intake of one of their meals, then reported their degree of postprandial sleepiness (Stanford Sleepiness Scale), average activity level, average hours of nightly sleep, and daytime sleepiness (Epworth Sleepiness Scale). The Dietary Inflammatory Index (DII) of the meal was estimated by adjusting DII parameters by 26%, reflecting the …


Differential Diagnosis Of Metastatic Bone Disease: A Case Study From The Ceaf Identified Skeletal Collection Of The University Of Pernambuco, Brazil [Diagnóstico Diferencial Da Doença Óssea Metastática: Um Estudo De Caso Da Coleção Esqueleto Identificado Do Ceaf Da Universidade De Pernambuco, Brasil], Evelyne Pessoa Soriano, Marcus Vitor Diniz De Carvalho, Emília Alves Do Nascimento, Rodrigo Araújo De Queiroz, Carina Marques, Eugénia Cunha Dec 2021

Differential Diagnosis Of Metastatic Bone Disease: A Case Study From The Ceaf Identified Skeletal Collection Of The University Of Pernambuco, Brazil [Diagnóstico Diferencial Da Doença Óssea Metastática: Um Estudo De Caso Da Coleção Esqueleto Identificado Do Ceaf Da Universidade De Pernambuco, Brasil], Evelyne Pessoa Soriano, Marcus Vitor Diniz De Carvalho, Emília Alves Do Nascimento, Rodrigo Araújo De Queiroz, Carina Marques, Eugénia Cunha

Anthropology Faculty Publications

This study aims to discuss the occurrence of pathological changes found in a skeleton from the Center for Studies in Forensic Anthropology (CEAF) Identified Skeletal Collection, Faculty of Odontology, University of Pernambuco (FOP/UPE), Brazil. The skeleton of a 47-year-old male that died in 2014 was macroscopically examined, and the differential diagnosis was performed based on clinical and paleopathological criteria. Lesions that were predominantly osteoclastic were observed in a multifocal pattern, mainly on the skull (29.6% of the total of lesions observed), pelvic bones (22.2%), and vertebrae (25.9%). The lesions morphology consists of elliptical osteolytic foci and areas of coalescent porosity, …


Emerging Themes In The Molecular Pathogenesis Of Enterotoxigenic Escherichia Coli, James M Fleckenstein, Alaullah Sheikh Dec 2021

Emerging Themes In The Molecular Pathogenesis Of Enterotoxigenic Escherichia Coli, James M Fleckenstein, Alaullah Sheikh

2020-Current year OA Pubs

Enterotoxigenic Escherichia coli (ETEC) are ubiquitous diarrheal pathogens that thrive in areas lacking basic human needs of clean water and sanitation. These genetically plastic organisms cause tremendous morbidity among disadvantaged young children, in the form of both acute diarrheal illness and sequelae of malnutrition and growth impairment. The recent discovery of additional plasmid-encoded virulence factors and elucidation of their critical role in the molecular pathogenesis of ETEC may inform new approaches to the development of broadly protective vaccines. Although the pathogens have been closely linked epidemiologically with nondiarrheal sequelae, these conditions remain very poorly understood. Similarly, while canonical effects of …


A Qualitative Study On Black East Asian Women And Their Experiences Of Hypersexualization, Kalya Castillo Dec 2021

A Qualitative Study On Black East Asian Women And Their Experiences Of Hypersexualization, Kalya Castillo

Seton Hall University Dissertations and Theses (ETDs)

While the adult multiracial population in the United States accounts for approximately 6.9 % of Americans, current growth trends suggest that numbers will triple within the next 40 years. Evidence suggests that Asian multiracial and Black multiracial groups are emergent racial categories, yet little research exists on dual minority populations. Premise for this qualitative study stems from my prior research on Black Asian American identity development that revealed an emergent theme of hypersexualization experienced by Black Asian American women. This study explored how Black Asian American women experience hypersexuality and the resulting impact on their identity development. Utilizing a constructivist–interpretivist …


Intensive Care Bundle With Blood Pressure Reduction In Acute Cerebral Hemorrhage Trial (Interact3): Study Protocol For A Pragmatic Stepped-Wedge Cluster-Randomized Controlled Trial, Lili Song, Xin Hu, Lu Ma, Xiaoying Chen, Menglu Ouyang, Laurent Billot, Qiang Li, Paula Muñoz-Venturelli, Carlos Abanto, Mohammad Wasay Dec 2021

Intensive Care Bundle With Blood Pressure Reduction In Acute Cerebral Hemorrhage Trial (Interact3): Study Protocol For A Pragmatic Stepped-Wedge Cluster-Randomized Controlled Trial, Lili Song, Xin Hu, Lu Ma, Xiaoying Chen, Menglu Ouyang, Laurent Billot, Qiang Li, Paula Muñoz-Venturelli, Carlos Abanto, Mohammad Wasay

Section of Neurology

Background: Early intensive blood pressure (BP) lowering remains the most promising treatment for acute intracerebral hemorrhage (ICH), despite discordant results between clinical trials and potential variation in the treatment effects by approach to control BP. As the third in a series of clinical trials on this topic, the INTEnsive care bundle with blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT3) aims to determine the effectiveness of a goal-directed care bundle protocol of early physiological control (intensive BP lowering, glycemic control, and pyrexia treatment) and reversal of anticoagulation, in acute ICH.
Methods: INTERACT3 is a pragmatic, international, multicenter, stepped-wedge (4 …


Recurrent Stroke Prediction Using Machine Learning Algorithms With Clinical Public Datasets: An Empirical Performance Evaluation, Fadratul Hafinaz Hassan, Mohd Adib Omar Dec 2021

Recurrent Stroke Prediction Using Machine Learning Algorithms With Clinical Public Datasets: An Empirical Performance Evaluation, Fadratul Hafinaz Hassan, Mohd Adib Omar

Baghdad Science Journal

Recurrent strokes can be devastating, often resulting in severe disability or death. However, nearly 90% of the causes of recurrent stroke are modifiable, which means recurrent strokes can be averted by controlling risk factors, which are mainly behavioral and metabolic in nature. Thus, it shows that from the previous works that recurrent stroke prediction model could help in minimizing the possibility of getting recurrent stroke. Previous works have shown promising results in predicting first-time stroke cases with machine learning approaches. However, there are limited works on recurrent stroke prediction using machine learning methods. Hence, this work is proposed to perform …


Noncovalently D-Arabinitol Molecularly Imprinted Polymers (Mips) To Identify Different Sugar Alcohols, Yuni Retnaningtyas, Ganden Supriyanto, Roedi Irawan, Siswandono Siswodihardjo Dec 2021

Noncovalently D-Arabinitol Molecularly Imprinted Polymers (Mips) To Identify Different Sugar Alcohols, Yuni Retnaningtyas, Ganden Supriyanto, Roedi Irawan, Siswandono Siswodihardjo

Baghdad Science Journal

Molecularly imprinted polymers (MIPs) are an effective method for separating enantiomeric compounds. The main objective of this research is to synthesize D-arabinitol MIPs, which can selectively separate D-arabinitol and its potential application to differentiate it from its enantiomer compound through a non-covalent approach. A macroporous polymer was synthesized using D-arabinitol as a template, acrylamide as a functional monomer, ethylene glycol dimethacrylate (EGDMA) being a cross-linker, dimethylsulfoxide (DMSO) being a porogen, as well as benzoyl peroxide being an initiator. After polymer synthesis, D-arabinitol was removed by a mixture of methanol and acetic acid (4:1, v/v). Fourier-Transform Infrared spectroscopy (FT-IR) and Scanning …


Temperature Stress On Physiological And Morphological Traits In Rhizophora Apiculata, Baseem M. Tamimi, Wan Juliana W. A., Nizam M. S., Che Radziah Che Mohd. Zain Dec 2021

Temperature Stress On Physiological And Morphological Traits In Rhizophora Apiculata, Baseem M. Tamimi, Wan Juliana W. A., Nizam M. S., Che Radziah Che Mohd. Zain

Baghdad Science Journal

Global warming has had considerable effects on vital ecosystems, which has also been caused by increased temperatures and CO2 that follow changes in different abiotic factors, which poses threats to mangrove forests environment. This research was conducted to examine the physiological and morphological characteristics of the Rhizophora apiculata mangrove regarding higher air temperature for the variety of tree species that respond to climate change. Seedlings were cultivated for three months in regulated growth chambers with three varying temperatures of 38°C, 21°C under CO2 at 450 ppm, and ambient CO2 concentration i.e., 450 ± 20 ppm under average temperature at 28°C …


Analysis Of The Social Entrepreneurship Ecosystem In Guanajuato, Mexico From Complex Social Networks, Vicente Espínola-Verdín, Luis Adolfo Torres-González Dec 2021

Analysis Of The Social Entrepreneurship Ecosystem In Guanajuato, Mexico From Complex Social Networks, Vicente Espínola-Verdín, Luis Adolfo Torres-González

Journal of Management for Global Sustainability

In Mexico, the interest in social enterprises has increased in the last 20 years as an alternative to the profit maximization approach of the company. They seek to solve a social problem, improve the conditions of the population they are targeting, modify the consumption habits of their clients, and seek social transformation through a social business model. The policies to promote entrepreneurship in the State of Guanajuato have focused mainly on the creation of traditional and, recently, technology-based enterprises with limited promotion of social entrepreneurship, which is sometimes confused with projects with low added value and without a clear strategy. …


Identifying Micrornas Panel Associated With Hepatocellular Carcinoma In Serum Of Chronic Hepatitis C Patients, Areeg Dabbish Dec 2021

Identifying Micrornas Panel Associated With Hepatocellular Carcinoma In Serum Of Chronic Hepatitis C Patients, Areeg Dabbish

Theses and Dissertations

Introduction: early detection of hepatocellular carcinoma (HCC) will reduce morbidity and mortality rates of this poorly diagnosed widely-spread disease. Dysregulation in microRNA (miRNAs) expression is associated with HCC progression. Objective: Is to identify a panel of differentially expressed miRNAs (DE-miRNAs) to enhance HCC early prediction in hepatitis C virus (HCV) infected patients. Methodology: Candidate miRNAs were selected using bioinformatic analysis of microarray and RNA-sequencing datasets, resulting in nine DE- miRNAs (miR-142, miR-150, miR-183, miR-199a, miR-215, miR-217, miR-224, miR-424 and miR-3607). Their expressions were validated in the serum of 44 healthy individuals, 62 non-cirrhotic HCV patients, 67 cirrhotic-HCV and 72 HCV-associated …


A Projection Method For The Estimation Of Error Covariance Matrices For Variational Data Assimilation In Ocean Modelling, Georgy I. Shapiro, Jose M. Gonzalez-Ondina, Lewis Sampson Dec 2021

A Projection Method For The Estimation Of Error Covariance Matrices For Variational Data Assimilation In Ocean Modelling, Georgy I. Shapiro, Jose M. Gonzalez-Ondina, Lewis Sampson

School of Biological and Marine Sciences

No abstract provided.


Principal Component Analysis In Paspalum Germplasm Characterization, A. Regitano Neto, L. A. R. Batista Dec 2021

Principal Component Analysis In Paspalum Germplasm Characterization, A. Regitano Neto, L. A. R. Batista

IGC Proceedings (1977-2023)

In a survey, through principal component analyses, for the most representative descriptors to be used in Paspalum germplasm characterization, 16 agronomic traits, 16 reproductive traits and 21 vegetative traits were evaluated in 32 accessions comprising Paspalum plicatulum (19) and Paspalum compressifolium (13) from the institutional germplasm collection. ANOVA for agronomic descriptors showed significant differences among accessions, except for percentage of dry matter in winter (DMW) which was not significant. Principal component analyses allowed reduction of 69%, 69% and 62%, respectively, in the initial number of descriptors, and the election of the most important for agronomic traits: DMYS, DMYW, RGS, CPPW …


Production And Quality Of Paspalum Forage In State Of São Paulo, L. A. R. Batista, A. Regitano Neto, Rodolfo Godoy Dec 2021

Production And Quality Of Paspalum Forage In State Of São Paulo, L. A. R. Batista, A. Regitano Neto, Rodolfo Godoy

IGC Proceedings (1977-2023)

Biomass produced by accessions of 26 species, belonging to 12 botanical groups of the genus Paspalum, collected in the south and central regions of Brazil, were evaluated during the first year of establishment for quantitative characteristics: production of dry biomass (DMY), percentage of dry matter (PDM) and regrowth score and qualitative traits: concentration of neutral detergent fiber (NDF), “in vitro” dry matter digestibility (IVDMD) and crude protein percentage in dry matter (CPPDM) -, in the central area of the state of São Paulo, in a completely randomized block design with two replications. The largest averages of DMY were obtained …


Study Of The Diversity Of Soil Animals Community In The Songnen Plain Grassland Of China, Xiuqin Yin, Tingcheng Zhu Dec 2021

Study Of The Diversity Of Soil Animals Community In The Songnen Plain Grassland Of China, Xiuqin Yin, Tingcheng Zhu

IGC Proceedings (1977-2023)

This paper dealt with the diversity in eight habitat soil animals communities in Songnen plain grassland. The results showed the better habitat condition the higher diversity index of soil animals, and vice-versa. The diversity of soil animals communities correlated positively with soil organic matter, total nitrogen, and negatively with soil pH; there was a poor correlation with soil water content and total soil phosphorus. The diversity of soil animals communities decreased with increasing depth of soil layer and has surface-collection.


Evaluating Varieties Of Alfalfa And Tall Fescue For Tolerance To Over-Grazing By Cattle, Robert F. Spitaleri, Jimmy C. Henning, Charles T. Dougherty, Garry D. Lacefield, B. T. Larson Dec 2021

Evaluating Varieties Of Alfalfa And Tall Fescue For Tolerance To Over-Grazing By Cattle, Robert F. Spitaleri, Jimmy C. Henning, Charles T. Dougherty, Garry D. Lacefield, B. T. Larson

IGC Proceedings (1977-2023)

Cultivars of alfalfa (Medicago sativa L.) and tall fescue (Festuca arundinacea Schreb.) were seeded in small (1.5 m x 4.6 m) plots and harvested for estimating yield the following spring. Plots were then grazed by cattle continuously for the remainder of the season so as to keep stand heights at 7.5 cm or less. This procedure was repeated for one or two more grazing seasons, depending on stand survival. Stands were visually rated for stand in the fall and spring. Marked differences in grazing tolerance were observed among alfalfa cultivars, following closely the commercial designations as grazing-type or …


The Role Of Cattle Dung In Seed Dispersal Of Major Species In A Zoysia Japonica Pasture In Japan, K. Shimoda, S. Sakanoue Dec 2021

The Role Of Cattle Dung In Seed Dispersal Of Major Species In A Zoysia Japonica Pasture In Japan, K. Shimoda, S. Sakanoue

IGC Proceedings (1977-2023)

To evaluate the role of cattle dung in seed dispersal of major species in Zoysia japonica pasture in Japan, we investigated the species composition and density of seeds in cattle dung by means of a germination test. Of 20 major species which had a mean coverage of more than 0.1%, 90% were detected as seeds in cattle dung. In addition, the species composition and density of seeds in cattle dung differed among three sampling seasons. Seeds of the six most prevalent species in terms of coverage were detected from cattle dung during the growing season. Hence, we conclude that it …


Stimulation Of Ammonia Oxidizer And Denitrifier Abundances By Nitrogen Loading: Poor Predictability For Increased Soil N2o Emission, Yong Zhang, Feng Zhang, Diego Abalos, Yiqi Luo, Dafeng Hui, Bruce A. Hungate, Pablo García-Palacios, Yakov Kuzyakov, Jørgen Eivind Olesen, Uffe Jørgensen, Ji Chen Dec 2021

Stimulation Of Ammonia Oxidizer And Denitrifier Abundances By Nitrogen Loading: Poor Predictability For Increased Soil N2o Emission, Yong Zhang, Feng Zhang, Diego Abalos, Yiqi Luo, Dafeng Hui, Bruce A. Hungate, Pablo García-Palacios, Yakov Kuzyakov, Jørgen Eivind Olesen, Uffe Jørgensen, Ji Chen

Biology Faculty Research

Unprecedented nitrogen (N) inputs into terrestrial ecosystems have profoundly altered soil N cycling. Ammonia oxidizers and denitrifiers are the main producers of nitrous oxide (N2O), but it remains unclear how ammonia oxidizer and denitrifier abundances will respond to N loading and whether their responses can predict N-induced changes in soil N2O emission. By synthesizing 101 field studies worldwide, we showed that N loading significantly increased ammonia oxidizer abundance by 107% and denitrifier abundance by 45%. The increases in both ammonia oxidizer and denitrifier abundances were primarily explained by N loading form, and more specifically, organic N …


The Immobilization Of Ticagrelor On Implant Materials And Corrosion And Biofouling Inhibition By Novel Layered Polymer Thin Films For Marine Application, Tell Lovelace Dec 2021

The Immobilization Of Ticagrelor On Implant Materials And Corrosion And Biofouling Inhibition By Novel Layered Polymer Thin Films For Marine Application, Tell Lovelace

Electronic Theses and Dissertations

Percutaneous coronary interventions are a widely used cardiovascular surgery which is typically accompanied by the insertion of a vascular stent. After the procedure patients are put on dual anti-platelet therapy (DAPT) to prevent stent thrombosis, a common complication to this procedure in which platelets aggregate in the blood vessel on the inserted stent. Systemic deactivation of platelets in patients via oral DAPT results in patients becoming bleeding risks in future medical procedures, necessitating the development of a localized delivery system for anti-platelet medications from the surface of the stent. A novel anti-thrombogenic vascular stent coating has been prepared by covalent …


Evaluation Of Residual Herbicides Across Multiple Rice Production Systems, Lucas Connor Webster Dec 2021

Evaluation Of Residual Herbicides Across Multiple Rice Production Systems, Lucas Connor Webster

LSU Doctoral Dissertations

A field study was conducted in 2019, 2020, and 2021 at the LSU Agricultural Center H. Rouse Caffey Rice Research Station (RRS) near Crowley, LA. to evaluate the crop safety and potential weed control of very long chain fatty acid (VLCFA) inhibiting herbicides in Louisiana rice production. The study evaluated the use of acetochlor, dimethenamid, s-metolachlor, and pyroxasulfone applied preemergence (PRE), delayed PRE (DPRE), and the two- to three- leaf, early postemergence (EPOST) rice growth stage. In general, rice injury decreased as application timing was delayed with the least amount of rice injury occurring when the VLCFA inhibiting herbicides were …


The Environmental Kuznets Curve For Deforestation In Indonesia, Dara Adila, Nunung Nuryartono, Mandar Oak Dec 2021

The Environmental Kuznets Curve For Deforestation In Indonesia, Dara Adila, Nunung Nuryartono, Mandar Oak

Economics and Finance in Indonesia

This study provides empirical findings on the relationship between deforestation and income in 32 provinces in Indonesia. To enrich the discussion on deforestation, this study investigates the impact of the factors of population, roundwood production, land area, and main crop production on deforestation. The selected main crops in Indonesia are oil palm, coffee, coconut, rubber, and cacao. The results confirm the existence of the EKC relationship between deforestation and income in Indonesia. The study also finds that oil palm production positively affects tree cover loss, but the production of natural rubber has the opposite impact on deforestation.


Identification Of Candidate Genes And Genomic Regions Associated With Adult Plant Resistance To Stripe Rust In Spring Wheat, Amira M. I. Mourad, Mohamed A. Abou-Zeid, Shamseldeen Eltaher, P. Stephen Baenziger, Andreas Börner Dec 2021

Identification Of Candidate Genes And Genomic Regions Associated With Adult Plant Resistance To Stripe Rust In Spring Wheat, Amira M. I. Mourad, Mohamed A. Abou-Zeid, Shamseldeen Eltaher, P. Stephen Baenziger, Andreas Börner

Department of Agronomy and Horticulture: Faculty Publications

Wheat stripe rust (caused by Puccinia striiformis f. sp. tritici) is a major disease that damages wheat plants and affects wheat yield all over the world. In recent years, stripe rust became a major problem that affects wheat yield in Egypt. New races appeared and caused breakdowns in the resistant genotypes. To improve resistance in the Egyptian genotypes, new sources of resistance are urgently needed. In the recent research, a set of 95 wheat genotypes collected from 19 countries, including Egypt, were evaluated for their resistance against the Egyptian race(s) of stripe rust under field conditions in the two …


A Cross-Ecoregion Evaluation Of Nitrogen Fixation And Denitrification In Streams And Rivers Of The United States Of America, Amy Marcarelli, Erin K. Eberhard, Michelle Kelly, Kevin Nevorski Dec 2021

A Cross-Ecoregion Evaluation Of Nitrogen Fixation And Denitrification In Streams And Rivers Of The United States Of America, Amy Marcarelli, Erin K. Eberhard, Michelle Kelly, Kevin Nevorski

Michigan Tech Publications, Part 1

It is typically assumed that dinitrogen (N2) fixation and denitrification are mutually exclusive processes in riverine ecosystems because N2 fixation is favored in high light, low nitrogen (N) environments but denitrification is favored under anoxic, high N conditions. Yet recent work in marine and lake ecosystems has demonstrated that N2 fixation can happen under high N conditions and in sediments, challenging this assumption. We conducted a cross-ecoregion study to test the hypothesis that N2 fixation and denitrification would co-occur in streams and rivers across a range of reactive N concentrations. Between 2017 and 2019, we sampled 30 streams in 13 …


Factors Influencing Economic Empowerment In Tourism Development, Eva Rachmawati, Joanna Fountain, Michael Mackay Dec 2021

Factors Influencing Economic Empowerment In Tourism Development, Eva Rachmawati, Joanna Fountain, Michael Mackay

Economics and Finance in Indonesia

Tourism is believed to be able to empower people economically, both at the individual and community levels, by providing various employment and business opportunities to community members to help alleviate poverty. This study offers insights into community empowerment outcome, particularly in economic dimension, through a quantitative approach. This study aims to identify the level of community empowerment outcome perceived by the local communities in tourism development in their area and analyze the factors that influence the outcome. Employing a mixed-methods approach, this study collected data through household survey, field and participatory observation, and document analysis. The questionnaire responses were analyzed …


Sleep And Risk For Metabolic Syndrome, Hypertension, Diabetes And Obesity Among Community-Dwelling Older Adults, Philip Zendels, Trudy L. Moore-Harrison, Jane F. Gaultney Dec 2021

Sleep And Risk For Metabolic Syndrome, Hypertension, Diabetes And Obesity Among Community-Dwelling Older Adults, Philip Zendels, Trudy L. Moore-Harrison, Jane F. Gaultney

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 88-102, 2022. Older adults often face a variety of health problems that are found less frequently in younger populations. Metabolic syndrome and other related diseases are common due to a variety of age and lifestyle factors. Sleep, often operationalized only as duration, quality, or apnea diagnosis, is associated with worse health outcomes across the lifespan. However, sleep is multi-faceted and may require a collection of measures in order to reflect this. This study examined a suite of self-reported sleep habits (risk for sleep apnea, night time duration, nap duration, quality, timing, and consistency of …


Effects Of Low Dose Caffeine On Post-Exercise Heart Rate Variability: A Double-Blind Placebo-Controlled Trial, Cagney T. Sargent, Tareq K. Shahbal, Andres E. Carrillo, Tania Amorim, Jason R. Edsall, Emily J. Ryan, Edward J. Ryan Dec 2021

Effects Of Low Dose Caffeine On Post-Exercise Heart Rate Variability: A Double-Blind Placebo-Controlled Trial, Cagney T. Sargent, Tareq K. Shahbal, Andres E. Carrillo, Tania Amorim, Jason R. Edsall, Emily J. Ryan, Edward J. Ryan

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 103-112, 2022. Caffeine may impact post-exercise heart rate variability (HRV); although, studies have yielded inconsistent findings. We examined the effects of low dose caffeine on post-exercise HRV. Healthy, college-aged adults [n = 18; age: 22.1 ± 2.6 years; BMI: 26.9 ± 4.3 kg/m2; estimated maximal oxygen consumption (VO2max): 45.1 ± 8.3 ml∙kg-1∙min-1] participated in a repeated-measures, double-blind, placebo-controlled trial. During the experimental trials, participants were fitted with a heart rate monitor and a mouthpiece with a one-way nonrebreathing valve and then rested for 10 min …


An Overview Of Drugs For The Treatment Of Mycobacterium Kansasii Pulmonary Disease, Shashikant Srivastava, Jotam G. Pasipanodya, Scott Heysell, Gunavanthi D. Boorgula, Tawanda Gumbo, Pamela J. Mcshane, Julie V. Philley Dec 2021

An Overview Of Drugs For The Treatment Of Mycobacterium Kansasii Pulmonary Disease, Shashikant Srivastava, Jotam G. Pasipanodya, Scott Heysell, Gunavanthi D. Boorgula, Tawanda Gumbo, Pamela J. Mcshane, Julie V. Philley

School of Medical and Biological Sciences Faculty Publications and Presentations

Objectives: The aim of this study was to determine and compare the efficacy of drugs to treat Mycobacterium kansasii (Mkn) pulmonary disease by performing minimum inhibitory concentration (MIC) determination and time-kill studies. Methods: We determined the MICs to 13 drugs against the Mkn standard laboratory strain ATCC 12478 and 20 clinical isolates and performed time-kill studies with 18 drugs from different classes using the standard laboratory strain of Mkn. The β-lactam antibiotics were tested with or without the combination of the β-lactamase inhibitor avibactam. An inhibitory sigmoid Emax model was used to describe the relationship between drug concentrations and bacterial …


Commencement [Program], December 18, 2021, University Of Northern Iowa Dec 2021

Commencement [Program], December 18, 2021, University Of Northern Iowa

UNI Commencement Programs

The program of the commencement ceremonies, including a list of institutional leadership, a list of the departments by college, awards given at the ceremonies, and a list of undergraduate and graduate degree candidates.


Differential Methods In Modern Biological Data Analysis, Micah Thornton Dec 2021

Differential Methods In Modern Biological Data Analysis, Micah Thornton

Statistical Science Theses and Dissertations

Analysis of biological data for differentiation of organisms/cells within and across species or even the same organism is important to a wide variety of applications. This work considers three different biological data sets at the genome, proteome, and epigenome levels: respectively, DNA sequences, glycosalation data, and DNA methylation. We explore some statistical modeling approaches for handling these modern datasets, and provide a relevant set of experiments for explanation and illustration.

First, genomic Fourier coefficients, which capture information about the harmonics of genetic sequences in terms of nucleotide pattern recurrence are investigated as summary metrics for medium sized virus genomes from …


Bayesian Multiple Instance Learning With Application To Cancer Detection Using Tcr Repertoire Sequencing Data, Danyi Xiong Dec 2021

Bayesian Multiple Instance Learning With Application To Cancer Detection Using Tcr Repertoire Sequencing Data, Danyi Xiong

Statistical Science Theses and Dissertations

As a branch of machine learning, multiple instance learning (MIL) learns from a collection of labeled bags, each containing a set of instances. Each instance is described by a feature vector. The learning process is weakly supervised due to ambiguous instance labels. Since its emergence, MIL has been applied to solve various problems including content-based image retrieval, object tracking/detection, and computer-aided diagnosis. In biomedical research, the use of MIL has been focused on medical image analysis and molecule activity prediction.

The first part of this dissertation focuses on a comparative study of MIL methods for a novel biomedical application. To …


2021 Fall Commencement, Harding University Dec 2021

2021 Fall Commencement, Harding University

Commencement Programs

Program for the Harding University Commencement on December 18.

Commencement Speaker: Dan Davidson