Digital Commons Network^™

Teaching Machine Learning In The Context Of Critical Quantitative Information Literacy, Carrie Diaz Eaton

All Faculty Scholarship

Bates College, is a small liberal arts postsecondary institution in the northeast United States. An information literacy course, Calling Bull, serves as an introductory data science class as well as a prerequisite-free quantitative literacy class. In this context, we spend a week discussing machine learning, with an emphasis on facial recognition algorithms. The emphasis is on the general algorithmic approach, critical inquiry of the process and careful interpretation of results presented in research or decision-making. This module relies on the use of open educational materials, discussion, and careful attention to issues of marginalization and algorithmic justice.

Open Science Via Hubzero: Exploring Five Science Gateways Supporting And Growing Their Open Science Communities, Sandra Gesing, Claire Stirm, Gerhard Klimeck, Lynn Zentner, Su Wang, Braulio Misael Villegas Martinez, Carrie Diaz Eaton, Sam Donovan, Lan Zhao, Carol Song, Et Al.

All Faculty Scholarship

The research landscape applying computational methods has become increasingly interdisciplinary and complex regarding the research computing ecosystem with novel hardware, software, data, and lab instruments. Reproducibility of research results, the usability of tools, and sharing of methods are all crucial for timely collaboration for research and teaching. HUBzero is a widely used science gateway framework designed to support online communities with efficient sharing and publication processes. The paper discusses the growth of communities for the five science gateways nanoHUB, MyGeoHub, QUBEShub & SCORE, CUE4CHNG, and HubICL using the HUBzero Platform to foster open science and tackling education with a diverse …

Exertional Heat Stroke In A Male High School Runner With Disordered Eating: A Disablement Model Case Study, Brittni G. Hoover, Rebecca M. Hirschhorn, Allison B. Smith, Amy F. Hand

Clinical Practice in Athletic Training

A 16-year-old male high school cross country athlete collapsed at the end of an afternoon 5K cross country meet. The patient was unable to stand, and after outwardly displaying confusion and agitation, his coaches sought assistance from the athletic trainers (ATs). The patient consumed one cup of water and a granola bar on the day of the meet. The ambient air temperature was 90°F with 69% humidity. Differential diagnoses included exertional heat stroke (EHS), exertional heat exhaustion, exertional collapse associated with sickle cell trait, heat syncope, dehydration, malnutrition, and hypoglycemia. Approximately 20 minutes passed between activation of the emergency action …

Characteristics Of Sickle Cell Trait Policies And Procedures At Ncaa Division I Institutions, H Parker, B J. Warner, D M. Gallegos, S A. Cage

Clinical Practice in Athletic Training

Context: In 2010, the National Collegiate Athletic Association (NCAA) introduced a proposal addressing sickle cell trait screening. This proposal later became a policy that required student-athletes in their first year of eligibility to provide their institution with accurate information regarding their sickle cell trait status. There does not appear to be a recent study published that has examined the sickle cell trait policies and procedures currently being used by NCAA Division I institutions. The purpose of this study was to describe the characteristics of sickle cell trait policies and procedures at NCAA Division I institutions. Methods: We used a web-based …

Rocky Mountain Forests Are Poised To Recover Following Bark Beetle Outbreaks But With Altered Composition, Kyle C. Rodman, Robert A. Andrus, Amanda R. Carlson, Trevor A. Carter, Teresa B. Chapman, Jonathan D. Coop, Paula J. Fornwalt, Nathan S. Gill, Brian J. Harvey, Ashley E. Hoffman, Katharine C. Kelsey, Dominik Kulakowski, Daniel C. Laughlin, Jenna E. Morris, José F. Negrón, Katherine M. Nigro, Gregory S. Pappas, Miranda D. Redmond, Charles C. Rhoades, Monique E. Rocca, Zoe H. Schapira, Jason S. Sibold, Camille S. Stevens-Rumann, Thomas T. Veblen, Jianmin Wang, Xiaoyang Zhang, Sarah J. Hart

Geography

Amplified by warming temperatures and drought, recent outbreaks of native bark beetles (Curculionidae: Scolytinae) have caused extensive tree mortality throughout Europe and North America. Despite their ubiquitous nature and important effects on ecosystems, forest recovery following such disturbances is poorly understood, particularly across regions with varying abiotic conditions and outbreak effects. To better understand post-outbreak recovery across a topographically complex region, we synthesized data from 16 field studies spanning subalpine forests in the Southern Rocky Mountains, USA. From 1997 to 2019, these forests were heavily affected by outbreaks of three native bark beetle species (Dendroctonus ponderosae, Dendroctonus rufipennis and Dryocoetes …

Raman Spectroscopy Reveals Phenotype Switches In Breast Cancer Metastasis, Santosh Kumar Paidi, Joel Rodriguez Troncoso, Mason G. Harper, Zhenhui Liu, Khue G. Nguyen, Sruthi Ravindranathan, Lisa Rebello, David E. Lee, Jesse D. Ivers, David A. Zaharoff, Narasimhan Rajaram, Ishan Barman

Biomedical Engineering Faculty Publications and Presentations

The accurate analytical characterization of metastatic phenotype at primary tumor diagnosis and its evolution with time are critical for controlling metastatic progression of cancer. Here, we report a label-free optical strategy using Raman spectroscopy and machine learning to identify distinct metastatic phenotypes observed in tumors formed by isogenic murine breast cancer cell lines of progressively increasing metastatic propensities. Methods: We employed the 4T1 isogenic panel of murine breast cancer cells to grow tumors of varying metastatic potential and acquired label-free spectra using a fiber probe-based portable Raman spectroscopy system. We used MCR-ALS and random forests classifiers to identify putative spectral …

The Influence Of Burn Severity On Post-Fire Spectral Recovery Of Three Fires In The Southern Rocky Mountains, Jaclyn Guz, Florencia Sangermano, Dominik Kulakowski

Geography

Increased wildfire activity and altered post-fire climate in the Southern Rocky Mountains has the potential to influence forest resilience. The Southern Rocky Mountains are a leading edge of climate change and have experienced record-breaking fires in recent years. The change in post-fire regeneration and forest resilience could potentially include future ecological trajectories. In this paper, we examined patterns of post-fire spectral recovery using Landsat time series. Additionally, we utilized random forest models to analyze the impact of climate and burn severity on three fire events in the Southern Rocky Mountains. Fifteen years following the fires, none of the burned stands …

Applying Landscape Fragmentation Analysis To Icescape Environments: Potential Impacts For The Pacific Walrus (Odobenus Rosmarus Divergens), Anthony Himmelberger, K E. Frey, Florencia Sangermano

Geography

Sea-ice cover across the Arctic has declined rapidly over the past several decades owing to amplified climate warming. The Pacific walrus (Odobenus rosmarus divergens) relies on sea-ice floes in the St. Lawrence Island (SLI) and Wainwright regions of the Bering and Chukchi seas surrounding Alaska as a platform for rest, feeding and reproduction. Lower concentrations of thick ice floes are generally associated with earlier seasonal fragmentation and shorter annual persistence of sea-ice cover, potentially affecting the life history of the Pacific walrus. In this study, 24 Landsat satellite images were classified into thick ice, thin ice or open water to …

Stress, Stress Appraisal And Coping In Athletic Trainers During The Covid-19 Pandemic, Lawson Holton

College of Graduate Studies: Theses & Dissertations

Introduction: There have been many studies conducted on the stress and mental health of frontline healthcare workers (HCWs) over the past months since the COVID-19 pandemic began. Very limited literature has examined the effect of the pandemic on athletic trainers (ATs). Objective: The aim of this investigation was to examine the stress, stress appraisal, and coping measures of ATs during the COVID-19 pandemic. Methods: Participants were recruited members from the National Athletic Trainers’ Association (NATA). The Perceived Stress Scale-10 was used to measure stress, the Stress Appraisal Measure was used to measure stress appraisal, and the Brief COPE was used …

The Need For Social Support From Law Schools During The Era Of Social Distancing, Michele Okoh, Inès Ndonko Nnoko

Faculty Scholarship

Law students have been faced with unparalleled stress during the syndemic. They must cope with being students during the COVID-19 pandemic but also must deal with stress related to social and political unrest. This essay recommends that law schools apply social support theory in developing interventions to effectively address the needs of law students now and in the future.

Social support theory focuses on the value and benefits one receives from positive interpersonal relationships. These positive relationships impact both mental and physical health and promote beneficial short and long-term overall health. However, not all supports are the same, and social …

Common Use, Lineage, And Lethality, Darrell A. H. Miller, Jennifer Tucker

Faculty Scholarship

Political and legal debates over assault rifles, large-capacity magazines, and other lethal technology are characterized by increasing rancor and hostility. Lack of a common vocabulary to describe the topics of debate, much less facilitate a constructive dialogue, only aggravates this trend. Sorely missing from the current debate is a shared vocabulary for what the public policy and the constitutional doctrine are aiming to achieve. Part I of this Article outlines the state of Second Amendment doctrine with respect to which and what type of arms are protected, and the confused language and goals of that doctrine. Part II provides a …

States' Public Health Funding And Population Health Outcomes: An Examination Through A Socio-Ecological Lens, Maureen K. Akubu-Odero

College of Graduate Studies: Theses & Dissertations

The US public health system has been underfunded for decades, despite its significant mandate of improving overall population health outcomes. This ecological study evaluates the association between state public health funding and population health outcomes and the role of state public health funding in reducing state-level health disparities. The findings show that the relationships between public health investments and improvements in health outcomes and health disparity in states are moderated by socioeconomic contextual factors. The findings suggest a need for continued and increased public health investments, tailored to community needs and context

Highway Stormwater Runoff On-Site Treatment Using Bioslope With New Media Of Biochar Amended Topsoils, Ahmed I. Yunus

College of Graduate Studies: Theses & Dissertations

Georgia Department of Transportation (GDOT) has constructed various treatment facilities on its right-of-way (ROW) to collect and treat highway stormwater runoff, emphasizing total suspended solids (TSS) removal. The permit performance goal set by the Georgia Environmental Protection Division (EPD) is 80% TSS removal. Current stormwater best management practice (BMP) treatment facilities include complex and permanent infrastructures such as bioslope, bioretention basins, sand filters, infiltration trenches, and grass channels. Among these BMPs, bioslope has been becoming more popular due to its applicability for roadway embankments and areas with limited ROW constraints. It removes pollutants effectively by physical filtration and chemical adsorption …

Nitrate Removal During The Shoulder Months In The Occoquan Reservoir: A Comprehensive Study, Km Risaduzzaman

College of Graduate Studies: Theses & Dissertations

The artificial nitrate addition by the Upper Occoquan Service Authority (UOSA)’s Water Reclamation Facility (WRF) to the Occoquan Reservoir during the warmer months has been proven to be an efficient way of maintaining the water quality of the reservoir. During the warmer months, the water body became thermally stratified, resulting in hypolimnetic anoxia and the subsequent release of undesired matters from the reduced sediments. At the end of the warmer months, the temperature began to decrease, and by the beginning of winter, oxygen became ubiquitous in water because of fall turnover. This condition remained stable until the following thermal stratification; …

Behavior And Chemical Signals As Markers Of Colony Identification In Argentine Ants (Linepithema Humile), Stephanie A. Rohrbach

College of Graduate Studies: Theses & Dissertations

Argentine ants, Linepithema humile, are a highly successful invasive species around the globe and are especially prominent in states such as California and the southeastern United States. L.humile have a unique form of unicoloniality, called “supercolonies”. L. humile can detect colonymates through scent markers in their outer cuticle. With these chemical markers, ants will exhibit high aggression if they smell different from one another. In our study, we performed aggression assays among ten different nest sites and analyzed their CHCs through gas chromatography mass spectrometry, or GC-MS, analysis. For our behavior results, while within-nest interactions displayed low aggression as …

Machine Learning Based Real-Time Quantification Of Production From Individual Clusters In Shale Wells, Ayodeji Luke Aboaba

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the last two decades, there has been advances in downhole monitoring in oil and gas wells with the use of Fiber-Optic sensing technology such as the Distributed Temperature Sensing (DTS). Unlike a conventional production log that provides only snapshots of the well performance, DTS provides continuous temperature measurements along the entire wellbore.

Whether by fluid extraction or injection, oil and gas production changes reservoir conditions, and continuous monitoring of downhole conditions is highly desirable. This research study presents a tool for real-time quantification of production from individual perforation clusters in a multi-stage shale well using Artificial Intelligence and Machine …

Microvascular Consequences Of Engineered Nanomaterial Inhalation Exposure And Subsequent Reproductive Outcomes, Krista Lee Garner

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nano-titanium dioxide (nano-TiO₂) is a commonly utilized engineered nanomaterial found ubiquitously in consumer products. While benefits of ENM utilization in are undeniable, nanoparticle inhalation has been linked to cardiovascular consequences and altered microvascular responses. Given these outcomes, it is important to explore vulnerable timepoints, such as gestation, as robust vascular adaptations are essential for maternofetal health.

The first aim of this dissertation was to assess myogenic responsiveness following maternal nano-TiO₂ inhalation. Fetal aortic responses were evaluated on gestational day (GD) 20 to assess how exposure may impact the F1 generation. Myogenic responsiveness within the uterine radial arteries …

Tetramerization Of Stat5 Has Opposing Roles In Governing Autoimmune Pathogenesis, Kelly Lynn Monaghan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Signal transducers and activators of transcription 5 (STAT5A and STAT5B) are members of the STAT protein family. STAT5 plays a critical role in mediating cellular responses following cytokine stimulation. Critical STAT5 signaling is achieved following functional dimerization, which occurs via SH2 domain interactions. The binding of two STAT5 dimers to tandemly linked TTCN₃GAA γ-interferon-activated sequence (GAS) motifs and N-terminal domain interactions, facilitates functional tetramerization. The biological role of STAT5 tetramers has been investigated using the Stat5a-Stat5b N-domain double knock-in (DKI) mouse strain, in which STAT5 tetramers cannot be formed due to substitutions in critical amino acid …

Evaluating Effects Of Sediment On Microbial Loading In A Drinking Water Distribution System, Erika Osborne

Graduate Theses, Dissertations, and Problem Reports (ETD)

Drinking water distribution systems (DWDS) are critical for protecting public health by ensuring safe water is transported from centralized treatment facilities to consumers. Sediment accumulation in DWDS is a common challenge that water utilities face that may pose some health risks when waterborne pathogens colonize biofilms formed on the sediment surface. Water utilities often establish flushing routines to help mitigate sediment accumulation in their system but the role that sediment plays in contributing to the total microbial loading in the system is unclear. The main objective of this study was to determine if sediment in a DWDS presents a significant …

Electronic Cigarette Dependence: User And Device Characteristic Predictors, Ashley E. Douglas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding the dependence potential of electronic cigarettes (ECIGs) is critical to informing prevention and regulatory efforts. Extant work on ECIG dependence is limited, in part due to the vast number of products that differ on their ability to deliver nicotine. Further, existing research is based largely on former/current cigarette smokers, and thus confounds dependence on nicotine via ECIGs versus cigarettes. This study evaluated ECIG device/liquid characteristics and use behaviors as predictors of ECIG dependence in a sample of experienced ECIG users who never smoked cigarettes. Participants completed an online survey that assessed ECIG device/liquid features, use behavior, and ECIG dependence. …

Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright

Graduate Theses, Dissertations, and Problem Reports (ETD)

The prevalence of chronic inflammatory diseases is on the rise. Some have posited the permeability of tight junctions in gastrointestinal epithelium tissues as a potential mechanism for precipitating inflammatory processes throughout the body. Zonulin is the only known modulator of tight junction permeability and has been implicated in numerous chronic inflammatory processes (e.g., proinflammatory cytokine production) and diseases, more generally. The role of zonulin in oral inflammation, however, has yet to be explored. Periodontal disease is the most common oral inflammatory condition and primary perpetrator of tooth loss. Periodontal disease also is associated with a number of other health problems …

A Domain Adaptation Approach For Segmenting Cell Instances In Microscopy Data, Matthew R. Keaton

Graduate Theses, Dissertations, and Problem Reports (ETD)

Automated cellular instance segmentation is a process that has been utilized for accelerating biological research since before the deep learning era, and recent advancements have produced higher quality results with less effort from the biologist. Most current endeavors focus on completely cutting the researcher out of the picture by generating highly generalized models. However, these models invariably fail when faced with novel data and effectively opt to miss out on the full capabilities of deep learning in pursuit of this goal. In our work, we demonstrate how, with even a minimal amount of annotated data, dominant approaches in this space …

Cytotoxic Effects Of Potential Irrigants For Endodontic Surgery, Kaiying Haggard

Graduate Theses, Dissertations, and Problem Reports (ETD)

Purpose: The aim of this study is to investigate if hypochlorous acid (Vashe and Endocyn), Ozone, sodium hypochlorite (0.5% NaOCl), chlorhexidine (0.12% CHX), and MTAD can be used as a disinfectant for endodontic surgery without causing bone tissue toxicity by comparing their cytotoxic effects to saline on osteoblasts in vitro.

Methods: Human Fetal Osteoblast Cells (hFOB 1.19, ATCC CRL-11372) were used. The cells viability after 10-minute exposure of Vashe, Endocyn, Ozone, NaOCl (0.5%), CHX (0.12%), MTAD, and saline at concentrations of 10, 30, 60, 90 % volume ratio were measured using CCK8 analysis and the absorbance were measured at 450 …

Healing Gardens For Assisted Living Facility At Cortland Acres, Thomas, Wv, Pooja Keshav Pawar

Graduate Theses, Dissertations, and Problem Reports (ETD)

The affection humans feel for nature is called biophilia. Connecting with nature helps in healing. The connection with nature can be established by incorporating biophilic elements like air, water, plants, and views of nature into the design. (Kellert,2018). According to Kaplan’s Attention Restoration theory, exposure to nature improves focus and the ability to concentrate. (Kaplan,1989)

Connecting with nature provides to be helpful in health care facilities for frail elderly, people with Alzheimer’s and Other Dementias, Hospice care facilities, Mental and Behavioral Health Facilities, and Assisted living facilities. (Marcus,2013)

The aim of this project is to create comfortable, safe, and accessible …

Epithelial Morphogenesis In The Drosophila Egg Chamber Requires Parvin And Ilk, Athina Keramidioti, Evgenia Golegou, Eleni Psarra, Nikolaos Paschalidis, Konstantina Kalodimou, Shinya Yamamoto, Christos Delidakis, Katerina M Vakaloglou, Christos G Zervas

Duncan NRI Faculty and Staff Publications

Integrins are the major family of transmembrane proteins that mediate cell-matrix adhesion and have a critical role in epithelial morphogenesis. Integrin function largely depends on the indirect connection of the integrin cytoplasmic tail to the actin cytoskeleton through an intracellular protein network, the integrin adhesome. What is currently unknown is the role of individual integrin adhesome components in epithelia dynamic reorganization. Drosophila egg chamber consists of the oocyte encircled by a monolayer of somatic follicle epithelial cells that undergo specific cell shape changes. Egg chamber morphogenesis depends on a developmental array of cell-cell and cell-matrix signalling events. Recent elegant work …

Emerging Roles Of Alternative Cleavage And Polyadenylation (Apa) In Human Disease, Prakash Dharmalingam, Rajasekaran Mahalingam, Hari Krishna Yalamanchili, Tingting Weng, Harry Karmouty-Quintana, Ashrith Guha, Rajarajan A Thandavarayan

Duncan NRI Faculty and Staff Publications

In the messenger RNA (mRNA) maturation process, the 3'-end of pre-mRNA is cleaved and a poly(A) sequence is added, this is an important determinant of mRNA stability and its cellular functions. More than 60%-70% of human genes have three or more polyadenylation (APA) sites and can be cleaved at different sites, generating mRNA transcripts of varying lengths. This phenomenon is termed as alternative cleavage and polyadenylation (APA) and it plays role in key biological processes like gene regulation, cell proliferation, senescence, and also in various human diseases. Loss of regulatory microRNA binding sites and interactions with RNA-binding proteins leading to …

Borderlands And Mestiza Consciousness In Appalachia: Latina Undergraduate Experiences In A Predominantly White Institution, Susana Mazuelas Quirce

Graduate Theses, Dissertations, and Problem Reports (ETD)

This qualitative phenomenological study explores the experiences of eight undergraduate Latinas in a Predominantly White Institution in the Appalachian region using Gloria Anzaldúa’s insights on Borderlands and Mestiza consciousness. A vast majority of the studies focused on the Latinx college student population that takes place in states and tertiary institutions with a dense concentration of Latinx population, leaving rural areas—especially the Appalachian region— unexplored. There is, as well, a scarcity of studies in research focused on four-year-degree-granting institutions in which Latinx are highly underrepresented. A substantial number of studies continue presenting Latinx students as a homogenous group despite their heterogeneity …

Examining Evolutionary Rate In Xiphosura, Samantha B. Ocon

Graduate Theses, Dissertations, and Problem Reports (ETD)

Horseshoe crabs, a group of aquatic chelicerate arthropods of the class Xiphosura, are strongly linked with the concept of “living fossils” – a term colloquially used to refer to clades that display a consistently low rate of morphological evolution through time. The concept of living fossils has been hotly debated, as it is considered to simplify or obscure millennia of evolutionary change. Recent methodological and computational advances in the paleobiological sciences have allowed for the investigation of these claims. Xiphosura are a model taxon for this type of investigative study because they exhibit a complex evolutionary history, despite their reputation …

Examining The Pulmonary Response To Repeated Vishniacozyma Victoriae Exposure And Its Association With Allergic Airway Disease, Rachael Erin Rush

Graduate Theses, Dissertations, and Problem Reports (ETD)

Allergic airway diseases such as asthma continue to increase in incidence in industrialized nations like the United States. These diseases are complex inflammatory processes involving numerous cells and mediators and are strongly influenced by fungal exposures. Recent developments in fungal detection methods have highlighted the contribution of Basidiomycota yeast species in indoor environments such as Vishniacozyma (syn. Cryptococcus) victoriae. However, despite the high levels of this yeast detected in indoor environments, very little is known about it or its role in respiratory morbidity. V. victoriae is phylogenetically similar to pathogenic Cryptococcus neoformans but lacks a capsule and is …

Evaluating Potential Soil Amendments And Geomorphic Methods For Mine Land Reclamation, Amanda Rodrigues Silva

Graduate Theses, Dissertations, and Problem Reports (ETD)

The United States has approximately 22% of the world’s coal reserves. Since 1961, the electric power sector has been the major user of coal in the U.S., accounting for 91.9% of the coal consumed in the country in 2021. Sixty-two percent of total U.S. coal production in 2021 was sourced from surface mining, and Wyoming, West Virginia, Pennsylvania, Illinois, and Montana were responsible for 74% of this total production.

Coal-mining activities expose sulfide minerals in rocks that, when in contact with oxidizing conditions, produce sulfate-rich drainage known as acid mine drainage (AMD). AMD treatment typically involves chemical treatments to raise …