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2021 Annual Report Of The Town Of Salisbury, New Hampshire For Fiscal Year Ending December 31, 2021., Salisbury Town Representatives

Salisbury, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

2021 Annual Report Town Of Deering, New Hampshire., Deering Town Representatives

Deering, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Recovery In Ten: An Inclusive Model Of Recovery For Rising Generations, Sydney Alexandra Camargo

Psychology Doctoral Specialization Projects

For decades, the 12-step model has been the go-to for substance use treatment. Programs such as Alcoholics Anonymous have given individuals in recovery the space to recover and reclaim their lives. However, research has shown this recovery to be directly influenced by the individual’s religion and his or her reliance on a higher power. For those who subscribe to a religion outside of Christianity, or have no religious backing at all, 12-step program can be disadvantageous. The lack of true inclusivity, as well as the verbal degradation of one’s self, has turned many away from this method. For those who …

Commercial Surrogacy: Building Families Outside Of Family Law, Sylvie Armstrong

UC Law SF Journal on Gender and Justice

Assisted Reproductive Technology continues to grow in popularity. Commercial surrogacy has proved no exception to this trend. However, lack of regulation at the international, federal, and state levels has given rise to a myriad of ethical and legal problems. This article considers the taxonomical question that any regulator must ask: Which field of law ought to be responsible for regulating this industry? It argues that although commercial surrogacy is often discussed as part of the family law rubric, on closer inspection, family law is fundamentally ill-suited to meet the needs of those involved in commercial surrogacy. By demonstrating the challenges …

Bostock: An Inevitable Guarantee Of Heightened Scrutiny For Sexual Orientation And Transgender Classifications, Kaleb Byars

Articles

n June 2020, the Supreme Court decided Bostock v. Clayton County. In Bostock, the Court held that discrimination on the basis of sexual orientation and transgender status per se constitutes discrimination "because of sex" for purposes of Title VIL But Bostock inspires the question of whether its holding and reasoning apply in other contexts, including the Equal Protection Clause context. While the Supreme Court has held intermediate scrutiny applies to sex classifications analyzed under the Equal Protection Clause, the Court has yet to elucidate the level of scrutiny that applies to LGBTQ classifications. Meanwhile, state and federal courts …

Predicting Cancer Immunotherapy Response From Gut Microbiomes Using Machine Learning Models, Hai Liang, Jay-Hyun Jo, Zhiwei Zhang, Margaret A Macgibeny, Jungmin Han, Diana M Proctor, Monica E Taylor, You Che, Paul Juneau, Andrea B Apolo, John A Mcculloch, Diwakar Davar, Hassane M Zarour, Amiran K Dzutsev, Isaac Brownell, Giorgio Trinchieri, James L Gulley, Heidi H Kong

Faculty, Staff and Student Publications

Cancer immunotherapy has significantly improved patient survival. Yet, half of patients do not respond to immunotherapy. Gut microbiomes have been linked to clinical responsiveness of melanoma patients on immunotherapies; however, different taxa have been associated with response status with implicated taxa inconsistent between studies. We used a tumor-agnostic approach to find common gut microbiome features of response among immunotherapy patients with different advanced stage cancers. A combined meta-analysis of 16S rRNA gene sequencing data from our mixed tumor cohort and three published immunotherapy gut microbiome datasets from different melanoma patient cohorts found certain gut bacterial taxa correlated with immunotherapy response …

Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee

Pitzer Senior Theses

Children occasionally encounter dysregulation when interacting with their parents in relatively neutral or positive scenarios. Given that the cause of dysregulation is usually relational, meaning it is often cued by someone who is seen to have power or control over the person, children could be particularly susceptible to dysregulation in the presence of their parents. However, when examining the existing literature, there appeared to be a lack of research and knowledge concerning this topic, with much of the literature focusing on the effect of child stressors on parental dysregulation. As a result, the term parent-prompted dysregulation was developed to refer …

Parent Adherence To Psychological Evaluation Recommendations, Feinstein Jessica D'Amico

All-Inclusive List of Electronic Theses and Dissertations

A psychological evaluation is often the first step towards intervention for children displaying difficulties associated with ADHD symptoms. The degree to which impairment associated with ADHD can be diminished relies in part on the extent to which patients follow through on recommendations that are provided as part of the psychological evaluation. Currently, there is little research that examines adherence to psychological evaluation recommendations. Two pioneer studies (Dreyer et al., 2010; Mucka et al., 2017) have found support for barriers and level of parent stress in predicting non-adherence to assessment recommendations. The present study expands upon previous research by examining adherence …

Access To The General Education Curriculum For Students With Significant Cognitive Disabilities, Robin Thoma

All-Inclusive List of Electronic Theses and Dissertations

As changes in legislation impact the education of students with significant cognitive disabilities, teachers must determine how to provide access to the general education curriculum. This is a particular challenge because of the intense needs of these students. Research was needed to examine the materials and instructional strategies utilized to provide access and the setting in which access was provided. In addition, factors that impact access required investigation. This qualitative, phenomenological study included five high school intense intervention educators who had lived experiences of providing access to the general education curriculum for students with significant cognitive disabilities. Observation and interviews …

Chemoresistance In Breast Cancer: Acquisition, Microtubule-Associated Proteins, And Combinatorial Therapy, Keeley Cleghorn

All-Inclusive List of Electronic Theses and Dissertations

Breast cancer remains the most diagnosed cancer in American women with a projected 44,000 women that will succumb to advanced metastatic disease in the next calendar year. Advanced and recurrent breast cancers frequently exhibit clinical resistance to therapeutic interventions including many that exhibit resistance against multiple drugs or therapies and results in chemoresistance. Chemoresistance, a common cause of therapeutic failure, can be classified as either innate or acquired, both of which result in dramatically different results following therapeutic intervention. Work in our laboratory has emphasized evaluating acquired chemoresistance against the microtubule-stabilizing drug, paclitaxel, and has demonstrated the ability to generate …

Haemosporidians & White-Throated Sparrows (Zonotrichia Albicollis): Parasite Diversity, Factors Influencing Infection, And Effects Of Infection On Fitness, Zoã© Delefortrie

All-Inclusive List of Electronic Theses and Dissertations

Host-parasite interactions play a significant role in the comprehension of co-evolutionary mechanisms such as the host-parasite arms race. Those co-evolutionary mechanisms allow a better understanding of the parasite distribution, emergence of zoonotic diseases, and the impact on hosts populations. In this Ph.D.dissertation, I study the interaction between haemosporidian parasites ( Plasmodium, Haemoproteus , and Leucocytozoon ) and a polymorphic species, the white-throated sparrow ( Zonotrichia albicollis ). First, I examined the occurrence of haemosporidian parasites in a breeding population of white-throated sparrows in the Adirondacks, NY, and assessed their parasite diversity. Then, I evaluated the landscape and individual characteristics influencing …

The Antiregulatory Arsenal, Antidemocratic Can(N)Ons, And The Waters Wars, William W. Buzbee

Case Western Reserve Law Review

No abstract provided.

The Impact Of Uncertainty Regarding Patent Eligible Subject Matter For Investment In U.S. Medical Diagnostic Technologies, A. Sasha Hoyt

Washington and Lee Law Review

Historically, 35 U.S.C. § 101, the statute governing patent eligible subject matter, has been construed broadly—with its legislative history indicating that it should cover “anything under the sun that is made by man.” The Supreme Court crafted three exceptions to § 101: (1) abstract ideas, (2) laws of nature, and (3) natural phenomena. In recent years, the Supreme Court’s eligibility jurisprudence has further narrowed § 101 to effectively exclude meritorious medical diagnostic methods. Indeed, since the Court’s decision in Mayo Collaborative Services v. Prometheus Laboratories, Inc., the Federal Circuit has held every single diagnostic method claim brought before it …

Developing A Circuit Model To Study The Mechanisms Of Dna Damage And Repair Feedback Dynamics In Cancer Cells, Thomas M. Deangelo

Honors Theses

Cancer therapies over the last decade have promoted a growing interest in the manipulation of DNA damage and repair pathways due to its beneficial consequences on cancer cell viability. Simultaneously attacking genetic code with DNA-damaging chemotherapies while eliminating mechanisms of DNA repair – the protectors of our genome – has enormous therapeutic potential. Biological circuit engineering interfaces biochemistry and systems biology with electrical engineering analyses to accurately model and simulate biological pathways such as DNA damage and repair. Circuit models can also be used to identify weaknesses within pathways, highlighting the most efficient protein targets for drugs that aim to …

Whose Nation Is This? Conceptualizing Burmese National Identity Through Case Studies Of Inter-Ethnic Conflict, Jason Leong

Honors Theses

The ongoing Rohingya Genocide is the most extreme expression of Burmese identity and has catapulted the nation of Myanmar onto the world stage. This thesis examines the development of a Burmese national identity during British colonial rule through the lens of inter-ethnic conflict between the Bamar ethnolinguistic majority and ethnic minorities living in colonial Myanmar. Through analyzing three different case studies, each representing a watershed expression of Burmese identity, this thesis illustrates how inter-ethnic conflict shaped what it means to be Burmese. Using archival material from the British Library such as political cartoons, government reports, and vernacular newspaper clippings, this …

Challenges Of Constructing Entrainment Map For Arbitrary Circadian Models, Yuxuan (Nelson) Wu

Honors Theses

The entrainment map, developed by Dr.Diekman and Dr.Bose, is claimed to be a 1-dimensional map that produces a better prediction for phase-locking than methods than the phase response curve for circadian models. In his paper, he constructs the entrainment map for the two-dimensional circadian model, the Novak-Tyson model, and the other two higher-dimensional circadian models. For this thesis, we concentrate on exploring if it is viable to construct the entrainment map for other circadian models that are not included in his paper: the Becker-Weimann model and the Relogio model. In addition, we discuss the challenges of constructing the entrainment map …

Understanding The Role Of Race In American Medicine, Fariel C. A. Lamountain

Honors Theses

Long running inequity in health care and outcomes in the United States stem from failure to acknowledge the underlying role of the Transatlantic slave trade as it manifests in all facets of American society and commerce. This paper focuses specifically on the American medical system and its foundations to understand the precursors to generational trends in lack of access to healthcare and poor health for Black communities. This paper uses a three-pronged approach to understand the racist cycle of inequity, highlighting the history and origins of racism in American medicine, personal accounts and statistical evidence of inequity, and community and …

El Cruce De Fronteras CinematográFicas De Carlos Reygadas: La Experiencia Afectiva De JapóN, Luz Silenciosa, Y Post Tenebras Lux, Minori K. Cohan

Honors Theses

El movimiento Nuevo Cine Mexicano de los años noventa marcó una nueva ola en la historia cinematográfica mexicana. Películas como Amores perros (Alejandro González Iñárritu, 2000), Y tu mamá también (Alfonso Cuarón, 2002), y Sexo, pudor, y lágrimas (Antonio Serrano, 1999), fueron dirigidas por algunos de los directores más reconocidos en México. Al mismo tiempo, Carlos Reygadas surgió en el mismo período, pero produjo películas que no podrían haber sido más diferentes a estas producciones, ya que el director empleaba actores no profesionales, filmaba en lugares rurales, y utilizó técnicas de slow cinema que crean una nueva experiencia fílmica. Sin …

Science And Sadness: Critiques On How We Handle Alzheimer’S Disease And Dementia, Katherine Martinez

Honors Theses

In our society, an individual’s worth is tied to the state of their cognitive function which affects the discourse about neurodegenerative illnesses, causing it to mostly fall under two branches: “The Dread” and “Science as the Holy Grail”. “The Dread” addresses how Alzheimer’s Disease (AD) and other dementias are typically perceived as devastating illnesses to be feared. “Science as the Holy Grail” represents the hope and faith that is invested into potential technoscientific developments without the guarantee of any consequential results. Limiting the narrative to these two categories negatively impacts the quality of life (QOL) of AD patients, caregivers, and …

The Chosen One?: Reflections On Mid-Century Egyptian Nationalism, Gamal Abdel Nasser's Charismatic Leadership, And The Suez Crisis Of 1956, Owen P.S. Hobbs

Honors Theses

This thesis considers Gamal Abdel Nasser's 1956 nationalization of the Suez Canal and the subsequent Suez Crisis in the broader context of the histories of nationalism and charismatic leadership in a decolonial setting. Chapter one synthesizes the works of notable scholars into a cohesive historiography of nationalism's emergence in Egypt and Nasser's unique role within mid-century Egyptian society. Chapter two examines the direct causes of the Suez Crisis within the previously established context of nationalism and charismatic leadership, drawing new conclusions from memos, telegrams, and the Egyptian Government's 'White Paper on the Nationalization of the Suez Canal Maritime Company' -- …

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …

Analyzing The Free Energy Of Ions Sampling A Voltage Gated Sodium Ion Channel, Isabel Varghese

Honors Theses

Voltage gated sodium ion channels are implicated in cardiac diseases, seizures, etc., and they play a role in maintaining ionic homeostasis in cells. Computational studies use prokaryotic model because they are simpler but function similarly to human voltage gated sodium ion channels. This study uses molecular dynamics (MD) to study three specific questions regarding voltage gated sodium ion channels of Magnetococcus marinus. The first question in this study is how the free energy of sodium diffusion compares to that of calcium ion diffusion. We were not able to find any physically significant information due to poor sampling and a lack …

"It’S Just Another Thing”: Perceptions Of Well Water Quality And Barriers In An Arsenic Hot Spot, Linzy Rosen

Honors Theses

Privately owned water is the primary source of drinking water for 43 million Americans. Although residential or private wells are susceptible to a variety of contaminants, the Safe Drinking Water Act of 1974 positions individuals as responsible for the testing, remediation, and management of this water. Despite the elevated presence of arsenic in Maine, which is linked to various cancers, cardiovascular disease, and neurological damage, little is known about how private well owners perceive the safety and quality of their own water.

This study takes a qualitative approach to understanding concerns and opinions by conducting semi - structured interviews with …

Double Trouble: The Development And Use Of A Novel Spatial Memory Task To Study Depression In A Female Rodent Model, Ekaterina L. Koelliker

Honors Theses

Preclinical rodent models of depression are important for improving our understanding of the behavioral and neurobiological implications of the disorder. However, the current behavioral assays used to assess depressive symptoms in rodents have substantial shortcomings; they are basic, test animals individually, and do not evaluate animals for extended periods. The primary goals of the present study, which was divided into two experiments, were to develop a novel task that could be used to study spatial memory and to apply the task to rodent models of depression. Both experiments used a circular arena with 10 identical jars to analyze the spatial …

The Multifront Battle Waged Against Female Autonomy: A Comparative Study Of Ancient Medical And Literary Texts, Leah K. Montello

Honors Theses

Male authors have long waged a multifront campaign against female independence. In this thesis, I focus on two specific fronts: literary and medical texts of the Classical Greek period. This thesis intends to explore the varying strategies in a selection of works, employed to reinforce prescribed gender norms. I approach this with a feminist lens to critique attempts made by elite educated Greek men to define what a woman ought to be like. I do not, however, explore every single tactic a medical and literary writer has applied to uphold patriarchal norms. My two body chapters revolve respectively around two …

Modeling Jadera Haematoloma’S Phenotypic Variation In The Context Of Its Developmental Plasticity, Michael C. Yorsz

Honors Theses

Phenotypic plasticity is the ability of an organism to integrate information from environmental cues to inform the development of its phenotype and remains understudied in biology. Models of plasticity are needed because evolution in the presence of plasticity is poorly understood. Jadera haematoloma, a hemimetabolous true bug, is an excellent animal model of plasticity, exhibiting a non-linear plastic response to juvenile nutrition that biases adult development into groups with differences in flight capability, wing shape, and fecundity. However, there is a lack of literature consensus regarding the range of developmental outcomes in the species. Some publications report the presence …

The Use Of Law To Address Space Debris Mitigation And Remediation: Looking Through A Science And Technology Lens, Annie Handmer, Steven Freeland

Journal of Air Law and Commerce

Increasingly over the past six decades, space exploration and technology have revolutionized the world we live in. The landscape in outer space has continued to evolve rapidly, presenting new challenges for a much slower moving legal framework as well as for peaceful uses of space more generally. In particular, space debris has emerged as a pressing global threat. In response, states have shifted towards a more informal two-pronged approach to outer space, as reflected by non-binding instruments adopted by the United Nations Committee on the Peaceful Uses of Outer Space (COPUOS), along with the development of technologies that aim to …

Remaining Human: How The Airline Deregulation Act Shields Commercial Air Carriers From Legal Liability For Mishandling Human Remains, Abigail A. Lahvis

Journal of Air Law and Commerce

The Airline Deregulation Act of 1978 (ADA) deregulated the domestic airline industry. Specifically, the ADA ended the dual administrative system, which allowed the states to regulate intrastate airfare and permitted the federal government’s Civil Aeronautics Board (CAB) to regulate interstate airfare. The Act also included a broad preemption clause to prevent the states from reimposing economic regulations on air travel. The preemption clause prohibits a “State . . . [from] enact[ing] or enforc[ing] any law, rule, regulation, standard, or other provision having the force and effect of law relating to rates, routes, or services of any air carrier.”

The Supreme …

Methodologies For Modeling Lithium-Ion Battery Capacity Degredation Based On Entropy Measures, Alireza Namdari

Doctoral Dissertations - College of Engineering

"Battery-based energy storage has been recognized as a crucial enabling technology in recent years. These energy storages are widely utilized in portable electronic devices, electric vehicles, and power grids. Appropriate battery health management facilitates avoiding catastrophic hazards and premature failure, and thus improving battery durability."

A Framework For Implementing Engineering Design For Additive Manufacturing Education, Lisa K. Murray

Doctoral Dissertations - College of Engineering

"Additive manufacturing (AM) is widely used in various industries and has transformed the way products are designed and manufactured. Training workshops in conjunction with a part assessment framework enable designers to use design for additive manufacturing (DfAM) considerations during the process of idea generation. A DfAM training framework will assist researchers, educators, and students to evaluate and improve designs and encourage exploration of changes that need to be made during the design process."